Impact of rapamycin on status epilepticus induced hippocampal pathology and weight gain

Experimental Neurology

Volumn 280, Issue , 2016, Pages 1-12

  Hester, Michael S ^a   Hosford, Bethany E ^a,b   Santos, Victor R ^a,c   Singh, Shatrunjai P ^a   Rolle, Isaiah J ^a,b   LaSarge, Candi L ^a   Liska, John P ^a   Garcia Cairasco, Norberto ^c   Danzer, Steve C ^a,b  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^b UNIVERSITY OF CINCINNATI   (United States)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Dentate granule cell; Dentate gyrus; Epilepsy; Epileptogenesis; Hippocampus; Inflammation; Mossy fiber sprouting; MTOR; Neurogenesis; Obesity; Rapamycin

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; PILOCARPINE; PROTEIN S6; RAPAMYCIN; CARRIER PROTEIN; GLI PROTEIN, MOUSE; IMMUNOSUPPRESSIVE AGENT; MEMBRANE PROTEIN; S6 KINASE; SLC30A3 PROTEIN, MOUSE; TRANSCRIPTION FACTOR GLI1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTOSIS; CELL FATE; CELL MATURATION; CONTROLLED STUDY; DENDRITE; DENTATE GYRUS; DENTATE HILUS; ENCEPHALITIS; ENZYME ACTIVATION; ENZYME INHIBITION; EPILEPTIC STATE; EPILEPTOGENESIS; FEMALE; GENETIC FATE MAPPING; GENETIC PROCEDURES; GRANULE CELL; HIPPOCAMPAL MOSSY FIBER; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NERVE CELL NECROSIS; NERVE SPROUTING; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; TRANSGENIC MOUSE; WEIGHT GAIN; ANIMAL; C57BL MOUSE; CELL MOTION; CHEMICALLY INDUCED; COMPLICATION; DISEASE MODEL; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; NERVE CELL; NERVOUS SYSTEM DEVELOPMENT; PATHOLOGY; SIGNAL TRANSDUCTION; STATUS EPILEPTICUS;

ANIMALS; CARRIER PROTEINS; CELL MOVEMENT; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; HIPPOCAMPUS; IMMUNOSUPPRESSIVE AGENTS; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MOSSY FIBERS, HIPPOCAMPAL; NEUROGENESIS; NEURONS; PILOCARPINE; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; SIGNAL TRANSDUCTION; SIROLIMUS; STATUS EPILEPTICUS; WEIGHT GAIN; ZINC FINGER PROTEIN GLI1;

EID: 84962323390     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2016.03.015     Document Type: Article

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