Rapamycin has age-, treatment paradigm-, and model-specific anticonvulsant effects and modulates neuropeptide y expression in rats

Epilepsia

Volumn 53, Issue 11, 2012, Pages 2015-2025

  Chachua, Tamar ^a,f   Poon, Ka Lai ^b,f   Yum, Mi Sun ^c,f   Nesheiwat, Leigh ^a,d   DeSantis, Kara ^a,e   Velíšková, Jana ^a   Velíšek, Libor ^a,f  

^a NEW YORK MEDICAL COLLEGE   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

^c University of Ulsan College of Medicine   (South Korea)

^d Department of Obstetrics Gynecology   (United States)

^e STATE UNIVERSITY OF NEW YORK   (United States)

^f ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Flurothyl; Kainic acid; N Methyl d aspartate; Pentylenetetrazole; Seizures

Indexed keywords

FLUROTHYL; KAINIC ACID; N METHYL DEXTRO ASPARTIC ACID; NEUROPEPTIDE Y; PENTETRAZOLE; RAPAMYCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DENTATE GYRUS; DRUG EFFICACY; DRUG TARGETING; HIPPOCAMPAL CA1 REGION; LONG TERM CARE; MALE; NONHUMAN; PRIMARY MOTOR CORTEX; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SEIZURE; SINGLE DRUG DOSE;

AGE FACTORS; ANIMALS; ANIMALS, NEWBORN; ANTICONVULSANTS; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; MALE; NEUROPEPTIDE Y; RATS; RATS, SPRAGUE-DAWLEY; SEIZURES; SIROLIMUS; TREATMENT OUTCOME;

EID: 84869080559     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/j.1528-1167.2012.03674.x     Document Type: Article

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