Rapamycin suppresses PTZ-induced seizures at different developmental stages of zebrafish

Pharmacology Biochemistry and Behavior

Volumn 139, Issue , 2015, Pages 163-168

  Siebel, Anna Maria ^a   Menezes, Fabiano Peres ^b   Da Costa Schaefer, Isabel ^b   Petersen, Bárbara Dutra ^b   Bonan, Carla Denise ^b  

^a Universidade Comunitaria Regional de Chapeco   (Brazil)

^b PONTIFICAL CATHOLIC UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

mTOR; Pentylenetetrazole; Rapamycin; Seizures; Zebrafish

Indexed keywords

RAPAMYCIN; VALPROIC ACID; ANTICONVULSIVE AGENT; CONVULSANT AGENT; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MULTIPROTEIN COMPLEX; PENTETRAZOLE; TARGET OF RAPAMYCIN KINASE; ZEBRAFISH PROTEIN;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DEVELOPMENTAL STAGE; FERTILIZATION; JUVENILE; LARVA; LATENT PERIOD; LOCOMOTION; NONHUMAN; PENTYLENETETRAZOLE-INDUCED SEIZURE; PRIORITY JOURNAL; TONIC CLONIC SEIZURE; ZEBRA FISH; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMICALLY INDUCED; DISEASE MODEL; DRUG EFFECTS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MOTOR ACTIVITY; PHYSIOLOGY; SEIZURES; SIGNAL TRANSDUCTION;

ANIMALS; ANTICONVULSANTS; CONVULSANTS; DISEASE MODELS, ANIMAL; LARVA; MOTOR ACTIVITY; MULTIPROTEIN COMPLEXES; PENTYLENETETRAZOLE; SEIZURES; SIGNAL TRANSDUCTION; SIROLIMUS; TOR SERINE-THREONINE KINASES; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 84949532978     PISSN: 00913057     EISSN: 18735177     Source Type: Journal    
DOI: 10.1016/j.pbb.2015.05.022     Document Type: Article

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