Selective pharmacogenetic inhibition of mammalian target of Rapamycin complex I (mTORC1) blocks long-term synaptic plasticity and memory storage

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 9, 2011, Pages 3791-3796

  Stoica, Loredana ^a   Zhu, Ping Jun ^a   Huang, Wei ^a   Zhou, Hongyi ^a   Kozma, Sara C ^b   Costa Mattioli, Mauro ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

Behavioral learning; Fear conditioning; Pharmacology

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; RAPAMYCIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONCENTRATION (PARAMETERS); DRUG ACTIVITY; GENETIC ANALYSIS; GENETIC MANIPULATION; LONG TERM MEMORY; LONG TERM POTENTIATION; LOW DRUG DOSE; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; PHARMACOGENETICS; PRIORITY JOURNAL; PROTEIN FUNCTION; SYNAPSE;

ACOUSTIC STIMULATION; ANIMALS; FEAR; LONG-TERM POTENTIATION; MEMORY, LONG-TERM; MICE; PHARMACOGENETICS; PROTEINS; SIROLIMUS; TRANS-ACTIVATORS;

MAMMALIA; MUS;

EID: 79952763934     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1014715108     Document Type: Article

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