메뉴 건너뛰기




Volumn 31, Issue 6, 2011, Pages 2337-2347

Rapamycin suppresses mossy fiber sprouting but not seizure frequency in a mouse model of temporal lobe epilepsy

Author keywords

[No Author keywords available]

Indexed keywords

RAPAMYCIN;

EID: 79951531485     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4852-10.2011     Document Type: Article
Times cited : (201)

References (114)
  • 1
    • 0024322622 scopus 로고
    • Glutamate decarboxylase-immunoreactive neurons are preserved in human epileptic hippocampus
    • Babb TL, Pretorius JK, Kupfer WR, Crandall PH (1989) Glutamate decarboxylase-immunoreactive neurons are preserved in human epileptic hippocampus. J Neurosci 9:2562-2574. (Pubitemid 19193586)
    • (1989) Journal of Neuroscience , vol.9 , Issue.7 , pp. 2562-2574
    • Babb, T.L.1    Pretorius, J.K.2    Kupfer, W.R.3    Crandall, P.H.4
  • 4
    • 8644280387 scopus 로고    scopus 로고
    • Contributions of mossy fiber and CA1 pyramidal cell sprouting to dentate granule cell hyperexcitability in kainic acid-treated hippocampal slice cultures
    • DOI 10.1152/jn.01028.2003
    • Bausch SB, McNamara JO (2004) Contributions of mossy fiber and CA1 pyramidal cell sprouting to dentate granule cell hyperexcitability in kainic acid-treated hippocampal slice cultures. J Neurophysiol 92:3582-3595. (Pubitemid 39506334)
    • (2004) Journal of Neurophysiology , vol.92 , Issue.6 , pp. 3582-3595
    • Bausch, S.B.1    McNamara, J.O.2
  • 6
    • 0032940256 scopus 로고    scopus 로고
    • Recurrent seizures and hippocampal sclerosis following intrahippocampal kainate injection in adult mice: Electroencephalography, histopathology and synaptic reorganization similar to mesial temporal lobe epilepsy
    • DOI 10.1016/S0306-4522(98)00401-1, PII S0306452298004011
    • Bouilleret V, Ridoux V, Depaulis A, Marescaux C, Nehlig A, Le Gal La Salle G (1999) Recurrent seizures and hippocampal sclerosis following intrahippocampal kainate injection in adult mice: electroencephalography, histopathology and synaptic reorganization similar to mesial temporal lobe epilepsy. Neuroscience 89:717-729. (Pubitemid 29070998)
    • (1999) Neuroscience , vol.89 , Issue.3 , pp. 717-729
    • Bouilleret, V.1    Ridoux, V.2    Depaulis, A.3    Marescaux, C.4    Nehlig, A.5    Le Gal La Salle, G.6
  • 7
    • 44249113841 scopus 로고    scopus 로고
    • Design logic of a cannabinoid receptor signaling network that triggers neurite outgrowth
    • Bromberg KD, Ma'ayan A, Neves SR, Iyengar R (2008) Design logic of a cannabinoid receptor signaling network that triggers neurite outgrowth. Science 320:903-909.
    • (2008) Science , vol.320 , pp. 903-909
    • Bromberg, K.D.1    Ma'ayan, A.2    Neves, S.R.3    Iyengar, R.4
  • 8
    • 0030773376 scopus 로고    scopus 로고
    • Neuron loss, granule cell axon reorganization, and functional changes in the dentate gyrus of epileptic kainate-treated rats
    • DOI 10.1002/(SICI)1096-9861(19970901)385:3<385::AID-CNE4>3.0.CO;2-#
    • Buckmaster PS, Dudek FE (1997) Neuron loss, granule cell axon reorganization, and functional changes in the dentate gyrus of epileptic kainatetreated rats. J Comp Neurol 385:385-404. (Pubitemid 27417924)
    • (1997) Journal of Comparative Neurology , vol.385 , Issue.3 , pp. 385-404
    • Buckmaster, P.S.1    Dudek, F.E.2
  • 9
    • 0033232724 scopus 로고    scopus 로고
    • Highly specific neuron loss preserves lateral inhibitory circuits in the dentate gyrus of kainate-induced epileptic rats
    • Buckmaster PS, Jongen-Rêlo AL (1999) Highly specific neuron loss preserves lateral inhibitory circuits in the dentate gyrus of kainate-induced epileptic rats. J Neurosci 19:9519-9529. (Pubitemid 30228103)
    • (1999) Journal of Neuroscience , vol.19 , Issue.21 , pp. 9519-9529
    • Buckmaster, P.S.1    Jongen-Relo, A.L.2
  • 10
    • 0036703768 scopus 로고    scopus 로고
    • Axon sprouting in a model of temporal lobe epilepsy creates a predominantly excitatory feedback circuit
    • Buckmaster PS, Zhang GF, Yamawaki R (2002) Axon sprouting in a model of temporal lobe epilepsy creates a predominantly excitatory feedback circuit. J Neurosci 22:6650-6658. (Pubitemid 35386421)
    • (2002) Journal of Neuroscience , vol.22 , Issue.15 , pp. 6650-6658
    • Buckmaster, P.S.1    Zhang, G.F.2    Yamawaki, R.3
  • 11
    • 67649382228 scopus 로고    scopus 로고
    • Inhibition of the mammalian target of rapamycin signaling pathway suppresses dentate granule cell axon sprouting in a rodent model of temporal lobe epilepsy
    • Buckmaster PS, Ingram EA, Wen X (2009) Inhibition of the mammalian target of rapamycin signaling pathway suppresses dentate granule cell axon sprouting in a rodent model of temporal lobe epilepsy. J Neurosci 29:8259-8269.
    • (2009) J Neurosci , vol.29 , pp. 8259-8269
    • Buckmaster, P.S.1    Ingram, E.A.2    Wen, X.3
  • 12
    • 0035924590 scopus 로고    scopus 로고
    • Chemotropic responses of retinal growth cones mediated by rapid local protein synthesis and degradation
    • DOI 10.1016/S0896-6273(01)00551-7
    • Campbell DS, Holt CE (2001) Chemotropic responses of retinal growth cones mediated by rapid local protein synthesis and degradation. Neuron 32:1013-1026. (Pubitemid 34075393)
    • (2001) Neuron , vol.32 , Issue.6 , pp. 1013-1026
    • Campbell, D.S.1    Holt, C.E.2
  • 13
    • 0024988456 scopus 로고
    • Progressive neuronal loss induced by kindling: A possible mechanism for mossy fiber synaptic reorganization and hippocampal sclerosis
    • DOI 10.1016/0006-8993(90)91054-K
    • Cavazos JE, Sutula TP (1990) Progressive neuronal loss induced by kindling: a possible mechanism for mossy fiber synaptic reorganization and hippocampal sclerosis. Brain Res 527:1-6. (Pubitemid 20290578)
    • (1990) Brain Research , vol.527 , Issue.1 , pp. 1-6
    • Cavazos, J.E.1    Sutula, T.P.2
  • 14
    • 0037424670 scopus 로고    scopus 로고
    • Ultrastructural features of sprouted mossy fiber synapses in kindled and kainic acid-treated rats
    • DOI 10.1002/cne.10581
    • Cavazos JE, Zhang P, Qazi R, Sutula TP (2003) Ultrastructural features of sprouted mossy fiber synapses in kindled and kainic acid-treated rats. J Comp Neurol 458:272-292. (Pubitemid 36297916)
    • (2003) Journal of Comparative Neurology , vol.458 , Issue.3 , pp. 272-292
    • Cavazos, J.E.1    Zhang, P.2    Qazi, R.3    Sutula, T.P.4
  • 15
    • 25144480287 scopus 로고    scopus 로고
    • Stereological analysis of forebrain regions in kainate-treated epileptic rats
    • DOI 10.1016/j.brainres.2005.07.058, PII S0006899305010991
    • Chen S, Buckmaster PS (2005) Stereological analysis of forebrain regions in kainate-treated epileptic rats. Brain Res 1057:141-152. (Pubitemid 41338097)
    • (2005) Brain Research , vol.1057 , Issue.1-2 , pp. 141-152
    • Chen, S.1    Buckmaster, P.S.2
  • 18
    • 0034002585 scopus 로고    scopus 로고
    • Cell damage and neurogenesis in the dentate granule cell layer of adult rats after pilocarpine- Or kainate-induced status epilepticus
    • DOI 10.1002/(SICI)1098-1063(2000)10:2<169::AID-HIPO6>3.0.CO;2-W
    • Covolan L, Ribeiro LTC, Longo BM, Mello LEAM (2000) Cell damage and neurogenesis in the dentate granule cell layer of adult rats after pilocarpine- or kainate-induced status epilepticus. Hippocampus 10:169-180. (Pubitemid 30216354)
    • (2000) Hippocampus , vol.10 , Issue.2 , pp. 169-180
    • Covolan, L.1    Ribeiro, L.T.C.2    Longo, B.M.3    Mello, L.E.A.M.4
  • 19
    • 0024208367 scopus 로고
    • Chronic seizures and collateral sprouting of dentate mossy fibers after kainic acid treatment in rats
    • DOI 10.1016/0006-8993(88)90681-6
    • Cronin J, Dudek FE (1988) Chronic seizures and collateral sprouting of dentate mossy fibers after kainic acid treatment in rats. Brain Res 474:181-184. (Pubitemid 19001195)
    • (1988) Brain Research , vol.474 , Issue.1 , pp. 181-184
    • Cronin, J.1    Dudek, F.E.2
  • 20
    • 34247111348 scopus 로고    scopus 로고
    • Rapamycin: Brain excitability studied in vitro
    • DOI 10.1111/j.1528-1167.2006.00976.x
    • Daoud D, Scheld HH, Speckmann E-J, Gorji A (2007) Rapamycin: brain excitability studied in vitro. Epilepsia 48:834-836. (Pubitemid 46587621)
    • (2007) Epilepsia , vol.48 , Issue.4 , pp. 834-836
    • Daoud, D.1    Scheld, H.H.2    Speckmann, E.-J.3    Gorji, A.4
  • 21
    • 0035793422 scopus 로고    scopus 로고
    • Ultrastructural features and synaptic connections of hilar ectopic granule cells in the rat dentate gyrus are different from those of granule cells in the granule cell layer
    • DOI 10.1016/S0006-8993(00)03119-X, PII S000689930003119X
    • Dashtipour K, Tran PH, Okazaki MM, Nadler JV, Ribak CE (2001) Ultrastructural features and synaptic connections of hilar ectopic granule cells in the rat dentate gyrus are different from those of granule cells in the granule cell layer. Brain Res 890:261-271. (Pubitemid 32115478)
    • (2001) Brain Research , vol.890 , Issue.2 , pp. 261-271
    • Dashtipour, K.1    Tran, P.H.2    Okazaki, M.M.3    Nadler, J.V.4    Ribak, C.E.5
  • 22
    • 0024412565 scopus 로고
    • Hippocampal interneuron loss and plasticity in human temporal lobe epilepsy
    • DOI 10.1016/0006-8993(89)90234-5
    • de Lanerolle NC, Kim JH, Robbins RJ, Spencer DD (1989) Hippocampal interneuron loss and plasticity in human temporal lobe epilepsy. Brain Res 495:387-395. (Pubitemid 19213577)
    • (1989) Brain Research , vol.495 , Issue.2 , pp. 387-395
    • De, L.N.C.1    Kim, J.H.2    Robbins, R.J.3    Spencer, D.D.4
  • 23
    • 0012882416 scopus 로고    scopus 로고
    • Comparison of commissural sprouting in the mouse and rat fascia dentata after entorhinal cortex lesion
    • DOI 10.1002/hipo.10118
    • Del Turco D, Woods AG, Gebhardt C, Phinney AL, Jucker M, Frotscher M, Deller T (2003) Comparison of commissural sprouting in the mouse rat fascia dentata after entorhinal cortex lesion. Hippocampus 13:685-699. (Pubitemid 37098757)
    • (2003) Hippocampus , vol.13 , Issue.6 , pp. 685-699
    • Del, T.D.1    Woods, A.G.2    Gebhardt, C.3    Phinney, A.L.4    Jucker, M.5    Frotscher, M.6    Deller, T.7
  • 24
    • 33846938488 scopus 로고    scopus 로고
    • Topological determinants of epileptogenesis in large-scale structural and functional models of the dentate gyrus derived from experimental data
    • DOI 10.1152/jn.00950.2006
    • Dyhrfjeld-Johnsen J, Santhakumar V, Morgan RJ, Huerta R, Tsimring L, Soltesz I (2007) Topological determinants of epileptogenesis in largescale structural and functional models of the dentate gyrus derived from experimental data. J Neurophysiol 97:1566-1587. (Pubitemid 46239529)
    • (2007) Journal of Neurophysiology , vol.97 , Issue.2 , pp. 1566-1587
    • Dyhrfjeld-Johnsen, J.1    Santhakumar, V.2    Morgan, R.J.3    Huerta, R.4    Tsimring, L.5    Soltesz, I.6
  • 25
    • 0035801604 scopus 로고    scopus 로고
    • Differential regulation of basic helix-loop-helix mRNAs in the dentate gyrus following status epilepticus
    • DOI 10.1016/S0306-4522(01)00198-1, PII S0306452201001981
    • Elliott RC, Khademi S, Pleasure SJ, Parent JM, Lowenstein DH (2001) Differential regulation of basic helix-loop-helix mRNAs in the dentate gyrus following status epilepticus. Neuroscience 106:79-88. (Pubitemid 32831075)
    • (2001) Neuroscience , vol.106 , Issue.1 , pp. 79-88
    • Elliott, R.C.1    Khademi, S.2    Pleasure, S.J.3    Parent, J.M.4    Lowenstein, D.H.5
  • 26
    • 0029042668 scopus 로고
    • Physiologic and morphologic characteristics of granule cell circuitry in human epileptic hippocampus
    • Franck JE, Pokorny J, Kunkel DD, Schwartzkroin PA (1995) Physiologic and morphologic characteristics of granule cell circuitry in human epileptic hippocampus. Epilepsia 36:543-558.
    • (1995) Epilepsia , vol.36 , pp. 543-558
    • Franck, J.E.1    Pokorny, J.2    Kunkel, D.D.3    Schwartzkroin, P.A.4
  • 29
    • 34248581590 scopus 로고    scopus 로고
    • Cyclicity of spontaneous recurrent seizures in pilocarpine model of temporal lobe epilepsy in rat
    • DOI 10.1016/j.expneurol.2007.03.008, PII S0014488607001045
    • Goffin K, Nissinen J, Van Laere K, Pitkänen A (2007) Cyclicity of spontaneous recurrent seizures in pilocarpine model of temporal lobe epilepsy in rat. Exp Neurol 205:501-505. (Pubitemid 46755770)
    • (2007) Experimental Neurology , vol.205 , Issue.2 , pp. 501-505
    • Goffin, K.1    Nissinen, J.2    Van Laere, K.3    Pitkanen, A.4
  • 30
    • 0035118635 scopus 로고    scopus 로고
    • Progression of spontaneous seizures after status epilepticus is associated with mossy fibre sprouting and extensive bilateral loss of hilar parvalbumin and somatostatin-immunoreactive neurons
    • DOI 10.1046/j.1460-9568.2001.01428.x
    • Gorter JA, van Vliet EA, Aronica E, Lopes da Silva FH (2001) Progression of spontaneous seizures after status epilepticus is associated with mossy fibre sprouting and extensive bilateral loss of hilar parvalbumin and somatostatin-immunoreactive neurons. Eur J Neurosci 13:657-669. (Pubitemid 32174791)
    • (2001) European Journal of Neuroscience , vol.13 , Issue.4 , pp. 657-669
    • Gorter, J.A.1    Van Vliet, E.A.2    Aronica, E.3    Lopes Da Silva, F.H.4
  • 31
    • 70449473508 scopus 로고    scopus 로고
    • Lipid raft-targeted Akt promotes axonal branching and growth cone expansion via mTOR and Rac1, respectively
    • Grider MH, Park D, Spencer DM, Shine HD (2009) Lipid raft-targeted Akt promotes axonal branching and growth cone expansion via mTOR and Rac1, respectively. J Neurosci Res 87:3033-3042.
    • (2009) J Neurosci Res , vol.87 , pp. 3033-3042
    • Grider, M.H.1    Park, D.2    Spencer, D.M.3    Shine, H.D.4
  • 32
    • 21644443575 scopus 로고    scopus 로고
    • Hippocampal granule cell activity and c-Fos expression during spontaneous seizures in awake, chronically epileptic, pilocarpine-treated rats: Implications for hippocampal epileptogenesis
    • DOI 10.1002/cne.20594
    • Harvey BD, Sloviter RS (2005) Hippocampal granule cell activity and c-fos expression during spontaneous seizures in awake, chronically epileptic, pilocarpine-treated rats: implications for hippocampal epileptogenesis. J Comp Neurol 488:442-463. (Pubitemid 40934682)
    • (2005) Journal of Comparative Neurology , vol.488 , Issue.4 , pp. 442-463
    • Harvey, B.D.1    Sloviter, R.S.2
  • 33
    • 0016167439 scopus 로고
    • Light microscopical mapping of the hippocampal region, the piriform cortex and the corticomedial amygdaloid nuclei of the rat with Timm's sulphide silver method
    • Haug, F-M Š (1974) Light microscopical mapping of the hippocampal region, the piriform cortex and the corticomedial amygdaloid nuclei of the rat with Timm's sulphide silver method. Z Anat Entwickl-Gesch 145:1-27.
    • (1974) Z Anat Entwickl-Gesch , vol.145 , pp. 1-27
    • Haug, F.-M.Š.1
  • 34
    • 0025203933 scopus 로고
    • Granule cell dispersion in the dentate gyrus of humans with temporal lobe epilepsy
    • Houser CR (1990) Granule cell dispersion in the dentate gyrus of humans with temporal lobe epilepsy. Brain Res 535:195-204.
    • (1990) Brain Res , vol.535 , pp. 195-204
    • Houser, C.R.1
  • 36
  • 37
    • 34248549590 scopus 로고    scopus 로고
    • Stereological analysis of GluR2-immunoreactive hilar neurons in the pilocarpine model of temporal lobe epilepsy: Correlation of cell loss with mossy fiber sprouting
    • DOI 10.1016/j.expneurol.2007.03.025, PII S0014488607001343
    • Jiao Y, Nadler JV (2007) Stereological analysis of GluR2-immunoreactive hilar neurons in the pilocarpine model of temporal lobe epilepsy: correlation of cell loss with mossy fiber sprouting. Exp Neurol 205:569-582. (Pubitemid 46755779)
    • (2007) Experimental Neurology , vol.205 , Issue.2 , pp. 569-582
    • Jiao, Y.1    Nadler, J.V.2
  • 38
    • 3042748274 scopus 로고    scopus 로고
    • Continuous cytosine-b-D-arabinofuranoside infusion reduces ectopic granule cells in adult rat hippocampus with attenuation of spontaneous recurrent seizures following pilocarpine-induced status epilepticus
    • DOI 10.1111/j.0953-816X.2004.03412.x
    • Jung K-H, Chu K, Kim M, Jeong S-W, Song Y-M, Lee S-T, Kim J-Y, Lee SK, Roh J-K (2004) Continuous cytosine-b-D-arabinofuranoside infusion reduces ectopic granule cells in adult rat hippocampus with attenuation of spontaneous recurrent seizures following pilocarpine-induced status epilepticus. Eur J Neurosci 19:3219-3226. (Pubitemid 38859539)
    • (2004) European Journal of Neuroscience , vol.19 , Issue.12 , pp. 3219-3226
    • Jung, K.-H.1    Chu, K.2    Kim, M.3    Jeong, S.-W.4    Song, Y.-M.5    Lee, S.-T.6    Kim, J.-Y.7    Lee, S.K.8    Roh, J.-K.9
  • 39
    • 37049032110 scopus 로고    scopus 로고
    • Neuropathogical features of a rat model for perinatal hypoxic-ischemic encephalopathy with associated epilepsy
    • DOI 10.1002/cne.21533
    • Kadam SD, Dudek FE (2007) Neuropathological features of a rat model for perinatal hypoxic-ischemic encephalopathy with associated epilepsy. J Comp Neurol 505:716-737. (Pubitemid 350247135)
    • (2007) Journal of Comparative Neurology , vol.505 , Issue.6 , pp. 716-737
    • Kadam, S.D.1    Dudek, F.E.2
  • 40
    • 33646504833 scopus 로고    scopus 로고
    • A model of posttraumatic epilepsy induced by lateral fluid-percussion brain injury in rats
    • Kharatishvili I, Nissinen JP, McIntosh TK, Pitkänen A (2006) A model of posttraumatic epilepsy induced by lateral fluid-percussion brain injury in rats. Neuroscience 140:685-697.
    • (2006) Neuroscience , vol.140 , pp. 685-697
    • Kharatishvili, I.1    Nissinen, J.P.2    McIntosh, T.K.3    Pitkänen, A.4
  • 44
    • 0028838991 scopus 로고
    • Suppression of pilocarpine-induced status epilepticus and the late development of epilepsy in rats
    • Lemos T, Cavalheiro EA (1995) Suppression of pilocarpine-induced status epilepticus and the late development of epilepsy in rats. Exp Brain Res 102:423-428.
    • (1995) Exp Brain Res , vol.102 , pp. 423-428
    • Lemos, T.1    Cavalheiro, E.A.2
  • 45
    • 68349100270 scopus 로고    scopus 로고
    • Rapamycin suppresses seizures and neuronal hypertrophy in a mouse model of cortical dysplasia
    • Ljungberg MC, Sunnen CN, Lugo JN, Anderson AE, D'Arcangelo G (2009) Rapamycin suppresses seizures and neuronal hypertrophy in a mouse model of cortical dysplasia. Dis Model Mech 2:389-398.
    • (2009) Dis Model Mech , vol.2 , pp. 389-398
    • Ljungberg, M.C.1    Sunnen, C.N.2    Lugo, J.N.3    Anderson, A.E.4    D'Arcangelo, G.5
  • 46
    • 0030909238 scopus 로고    scopus 로고
    • Blockade of pilocarpine- Or kainate-induced mossy fiber sprouting by cycloheximide does not prevent subsequent epileptogenesis in rats
    • DOI 10.1016/S0304-3940(97)00267-X, PII S030439409700267X
    • Longo BM, Mello LEAM (1997) Blockade of pilocarpine- or kainate-induced mossy fiber sprouting by cycloheximide does not prevent subsequent epileptogenesis in rats. Neurosci Lett 226:163-166. (Pubitemid 27201969)
    • (1997) Neuroscience Letters , vol.226 , Issue.3 , pp. 163-166
    • Longo, B.M.1    Mello, L.E.A.M.2
  • 47
    • 0032168481 scopus 로고    scopus 로고
    • Supragranular mossy fiber sprouting is not necessary for spontaneous seizures in the intrahippocampal kainate model of epilepsy in the rat
    • DOI 10.1016/S0920-1211(98)00049-7, PII S0920121198000497
    • Longo BM, Mello LEAM (1998) Supragranular mossy fiber sprouting is not necessary for spontaneous seizures in the intrahippocampal kainate model of epilepsy in the rat. Epilepsy Res 32:172-182. (Pubitemid 28419487)
    • (1998) Epilepsy Research , vol.32 , Issue.1-2 , pp. 172-182
    • Longo, B.M.1    Mello, L.E.A.M.2
  • 48
    • 0037403820 scopus 로고    scopus 로고
    • Sprouting of mossy fibers and the vacating of postsynaptic targets in the inner molecular layer of the dentate gyrus
    • DOI 10.1016/S0014-4886(02)00046-8
    • Longo BM, Covolan L, Chadi G, Mello LEAM (2003) Sprouting of mossy fibers and the vacating of postsynaptic targets in the inner molecular layer of the dentate gyrus. Exp Neurol 181:57-67. (Pubitemid 36438676)
    • (2003) Experimental Neurology , vol.181 , Issue.1 , pp. 57-67
    • Longo, B.1    Covolan, L.2    Chadi, G.3    Mello, L.E.A.M.4
  • 49
    • 0033975195 scopus 로고    scopus 로고
    • Recurrent excitatory connectivity in the dentate gyrus of kindled and kainic acid-treated rats
    • Lynch M, Sutula T (2000) Recurrent excitatory connectivity in the dentate gyrus of kindled and kainic acid-treated rats. J Neurophysiol 83:693-704. (Pubitemid 30091281)
    • (2000) Journal of Neurophysiology , vol.83 , Issue.2 , pp. 693-704
    • Lynch, M.1    Sutula, T.2
  • 50
    • 2342565072 scopus 로고    scopus 로고
    • AMPA receptor alterations precede mossy fiber sprouting in young children with temporal lobe epilepsy
    • DOI 10.1016/j.neuroscience.2004.03.004, PII S0306452204001769
    • Lynd-Balta E, Pilcher WH, Joseph SA (2004) AMPA receptor alterations precede mossy fiber sprouting in young children with temporal lobe epilepsy. Neuroscience 126:105-114. (Pubitemid 38609110)
    • (2004) Neuroscience , vol.126 , Issue.1 , pp. 105-114
    • Lynd-Balta, E.1    Pilcher, W.H.2    Joseph, S.A.3
  • 51
    • 0013950709 scopus 로고
    • Epilepsy and the temporal lobes
    • Margerison JH, Corsellis JAN (1966) Epilepsy and the temporal lobes. Brain 89:499-530.
    • (1966) Brain , vol.89 , pp. 499-530
    • Margerison, J.H.1    Corsellis, J.A.N.2
  • 52
    • 0026579324 scopus 로고
    • The functional relationship between antidromically evoked field responses of the dentate gyrus and mossy fiber reorganization in temporal lobe epileptic patients
    • Masukawa LM, Uruno K, Sperling M, O'Connor MJ, Burdette LJ (1992) The functional relationship between antidromically evoked field responses of the dentate gyrus and mossy fiber reorganization in temporal lobe epileptic patients. Brain Res 579:119-127.
    • (1992) Brain Res , vol.579 , pp. 119-127
    • Masukawa, L.M.1    Uruno, K.2    Sperling, M.3    O'Connor, M.J.4    Burdette, L.J.5
  • 53
    • 0027442075 scopus 로고
    • Hippocampal EEG excitability and chronic spontaneous seizures are associated with aberrant synaptic reorganization in the rat intrahippocampal kainate model
    • DOI 10.1016/0013-4694(93)90186-Y
    • Mathern GW, Cifuentes F, Leite JP, Pretorius JK, Babb TL (1993) Hippocampal EEG excitability and chronic spontaneous seizures are associated with aberrant synaptic reorganization in the rat intrahippocampal kainate model. EEG Clin Neurophysiol 87:326-339. (Pubitemid 23328867)
    • (1993) Electroencephalography and Clinical Neurophysiology , vol.87 , Issue.5 , pp. 326-339
    • Mathern, G.W.1    Cifuentes, F.2    Leite, J.P.3    Pretorius, J.K.4    Babb, T.L.5
  • 54
    • 0028870168 scopus 로고
    • Quantified patterns of mossy fiber sprouting and neuron densities in hippocampal and lesional seizures
    • Mathern GW, Pretorius JK, Babb TL (1995) Quantified patterns of mossy fiber sprouting and neuron densities in hippocampal and lesional seizures. J Neurosurg 82:211-219.
    • (1995) J Neurosurg , vol.82 , pp. 211-219
    • Mathern, G.W.1    Pretorius, J.K.2    Babb, T.L.3
  • 56
    • 33750286710 scopus 로고    scopus 로고
    • Stereological methods reveal the robust size and stability of ectopic hilar granule cells after pilocarpine-induced status epilepticus in the adult rat
    • DOI 10.1111/j.1460-9568.2006.05101.x
    • McCloskey DP, Hintz TM, Pierce JP, Scharfman HE (2006) Stereological methods reveal the robust size and stability of ectopic hilar granule cells after pilocarpine-induced status epilepticus in the adult rat. Eur J Neurosci 24:2203-2210. (Pubitemid 44622341)
    • (2006) European Journal of Neuroscience , vol.24 , Issue.8 , pp. 2203-2210
    • McCloskey, D.P.1    Hintz, T.M.2    Pierce, J.P.3    Scharfman, H.E.4
  • 57
    • 34250626014 scopus 로고    scopus 로고
    • A mouse model of tuberous sclerosis: Neuronal loss of Tsc1 causes dysplastic and ectopic neurons, reduced myelination, seizure activity, and limited survival
    • DOI 10.1523/JNEUROSCI.5540-06.2007
    • Meikle L, Talos DM, Onda H, Pollizzi K, Rotenberg A, Sahin M, Jensen FE, Kwiatkowski DJ (2007) A mouse model of tuberous sclerosis: neuronal loss of Tsc1 causes dysplastic and ectopic neurons, reduced myelination, seizure activity, and limited survival. J Neurosci 27:5546-5558. (Pubitemid 350021088)
    • (2007) Journal of Neuroscience , vol.27 , Issue.21 , pp. 5546-5558
    • Meikle, L.1    Talos, D.M.2    Onda, H.3    Pollizzi, K.4    Rotenberg, A.5    Sahin, M.6    Jensen, F.E.7    Kwiatkowski, D.J.8
  • 59
    • 0029963894 scopus 로고    scopus 로고
    • Lack of Fos-like immunoreactivity after spontaneous seizures or reinduction of status epilepticus by pilocarpine in rats
    • DOI 10.1016/0304-3940(96)12562-3
    • Mello LEAM, Kohman CM, Tan AM, Cavalheiro EA, Finch DM (1996) Lack of Fos-like immunoreactivity after spontaneous seizures or reinduction of status epilepticus by pilocarpine in rats. Neurosci Lett 208:133-137. (Pubitemid 26128123)
    • (1996) Neuroscience Letters , vol.208 , Issue.2 , pp. 133-137
    • Mello, L.E.A.M.1    Kohman, C.M.2    Tan, A.M.3    Cavalheiro, E.A.4    Finch, D.M.5
  • 60
    • 0032857293 scopus 로고    scopus 로고
    • Mossy fiber-granule cell synapses in the normal and epileptic rat dentate gyrus studied with minimal laser photostimulation
    • Molnár P, Nadler JV (1999) Mossy fiber-granule cell synapses in the normal and epileptic rat dentate gyrus studied with minimal laser photostimulation. J Neurophysiol 82:1883-1894. (Pubitemid 29471276)
    • (1999) Journal of Neurophysiology , vol.82 , Issue.4 , pp. 1883-1894
    • Molnar, P.1    Nadler, J.V.2
  • 61
    • 0019258781 scopus 로고
    • Epilepsy and neuron loss in the hippocampus
    • Mouritzen Dam A (1980) Epilepsy and neuron loss in the hippocampus. Epilepsia 21:617-629.
    • (1980) Epilepsia , vol.21 , pp. 617-629
    • Mouritzen Dam, A.1
  • 62
    • 0018907951 scopus 로고
    • Selective innervation of hippocampal area CA1 and the fascia dentata after destruction of CA3-CA4 afferents with kainic acid
    • DOI 10.1016/0006-8993(80)90825-2
    • Nadler JV, Perry BW, Cotman CW (1980) Selective reinnervation of hippocampal area CA1 and the fascia dentata after destruction of CA3-CA4 afferents with kainic acid. Brain Res 182:1-9. (Pubitemid 10173688)
    • (1980) Brain Research , vol.182 , Issue.1 , pp. 1-9
    • Nadler, J.V.1    Perry, B.W.2    Cotman, C.W.3
  • 64
    • 0034939296 scopus 로고    scopus 로고
    • Is mossy fiber sprouting present at the time of the first spontaneous seizures in rat experimental temporal lobe epilepsy?
    • Nissinen J, Lukasiuk K, Pitkänen A (2001) Is mossy fiber sprouting present at the time of the first spontaneous seizures in rat experimental temporal lobe epilepsy? Hippocampus 11:299-310.
    • (2001) Hippocampus , vol.11 , pp. 299-310
    • Nissinen, J.1    Lukasiuk, K.2    Pitkänen, A.3
  • 65
    • 0028911542 scopus 로고
    • Hippocampal mossy fiber sprouting and synapse formation after status epilepticus in rats: Visualization after retrograde transport of biocytin
    • Okazaki MM, Evenson DA, Nadler JV (1995) Hippocampal mossy fiber sprouting and synapse formation after status epilepticus in rats: visualization after retrograde transport of biocytin. J Comp Neurol 352:515-534.
    • (1995) J Comp Neurol , vol.352 , pp. 515-534
    • Okazaki, M.M.1    Evenson, D.A.2    Nadler, J.V.3
  • 66
    • 0030907041 scopus 로고    scopus 로고
    • Dentate granule cell neurogenesis is increased by seizures and contributes to aberrant network reorganization in the adult rat hippocampus
    • Parent JM, Yu TW, Leibowitz RT, Geschwind DH, Sloviter RS, Lowenstein DH (1997) Dentate granule cell neurogenesis is increased by seizures and contributes to aberrant network reorganization in the adult rat hippocampus. J Neurosci 17:3727-3738. (Pubitemid 27200597)
    • (1997) Journal of Neuroscience , vol.17 , Issue.10 , pp. 3727-3738
    • Parent, J.M.1    Yu, T.W.2    Leibowitz, R.T.3    Geschwind, D.H.4    Sloviter, R.S.5    Lowenstein, D.H.6
  • 69
    • 0031952614 scopus 로고    scopus 로고
    • Physiological unmasking of new glutamatergic pathways in the dentate gyrus of hippocampal slices from kainate-induced epileptic rats
    • Patrylo PR, Dudek FE (1998) Physiological unmasking of new glutamatergic pathways in the dentate gyrus of hippocampal slices form kainate-induced epileptic rats. J Neurophysiol 79:418-429. (Pubitemid 28133832)
    • (1998) Journal of Neurophysiology , vol.79 , Issue.1 , pp. 418-429
    • Patrylo, P.R.1    Dudek, F.E.2
  • 70
    • 23444450278 scopus 로고    scopus 로고
    • Temporal patterns of Fos expression in the dentate gyrus after spontaneous seizures in a mouse model of temporal lobe epilepsy
    • DOI 10.1523/JNEUROSCI.0838-05.2005
    • Peng Z, Houser CR (2005) Temporal patterns of fos expression in the dentate gyrus after spontaneous seizures in a mouse model of temporal lobe epilepsy. J Neurosci 25:7210-7220. (Pubitemid 41113937)
    • (2005) Journal of Neuroscience , vol.25 , Issue.31 , pp. 7210-7220
    • Peng, Z.1    Houser, C.R.2
  • 71
    • 27744516874 scopus 로고    scopus 로고
    • Mossy fibers are the primary source of afferent input to ectopic granule cells that are born after pilocarpine-induced seizures
    • DOI 10.1016/j.expneurol.2005.08.007, PII S0014488605002815
    • Pierce JP, Melton J, Punsoni M, McCloskey DP, Scharfman HE (2005) Mossy fibers are the primary source of afferent input to ectopic granule cells that are born after pilocarpine-induced seizures. Exp Neurol 196:316-331. (Pubitemid 41607820)
    • (2005) Experimental Neurology , vol.196 , Issue.2 , pp. 316-331
    • Pierce, J.P.1    Melton, J.2    Punsoni, M.3    McCloskey, D.P.4    Scharfman, H.E.5
  • 73
    • 13444291401 scopus 로고    scopus 로고
    • Administration of diazepam during status epilepticus reduces development and severity of epilepsy in rat
    • DOI 10.1016/j.eplepsyres.2004.10.003
    • Pitkänen A, Kharatishvili I, Narkilahti S, Lukasiuk K, Nissinen J (2005) Administration of diazepam during status epilepticus reduces development and severity of epilepsy in rat. Epilepsy Res 63:27-42. (Pubitemid 40215778)
    • (2005) Epilepsy Research , vol.63 , Issue.1 , pp. 27-42
    • Pitkanen, A.1    Kharatishvili, I.2    Narkilahti, S.3    Lukasiuk, K.4    Nissinen, J.5
  • 74
    • 0034663303 scopus 로고    scopus 로고
    • Unique expression patterns of cell fate molecules delineate sequential stages of dentate gyrus development
    • Pleasure SJ, Collins AE, Lowenstein DH (2000) Unique expression patterns of cell fate molecules delineate sequential stages of dentate gyrus development. J Neurosci 20:6095-6105. (Pubitemid 30658403)
    • (2000) Journal of Neuroscience , vol.20 , Issue.16 , pp. 6095-6105
    • Pleasure, S.J.1    Collins, A.E.2    Lowenstein, D.H.3
  • 75
    • 0037756764 scopus 로고    scopus 로고
    • Associational sprouting in the mouse fascia dentata after entorhinal lesion in vitro
    • DOI 10.1016/S0006-8993(03)02836-1
    • Prang P, Del Turco D, Deller T (2003) Associational sprouting in the mouse fascia dentata after entorhinal lesion in vitro. Brain Res 978:205-212. (Pubitemid 36776640)
    • (2003) Brain Research , vol.978 , Issue.1-2 , pp. 205-212
    • Prang, P.1    Del, T.D.2    Deller, T.3
  • 76
    • 0015309163 scopus 로고
    • Modification of seizure activity by electrical stimulation: II. Motor seizure
    • Racine RJ (1972) Modification of seizure activity by electrical stimulation: II. Motor seizure. Electroencephalogr Clin Neurophysiol 32:281-294.
    • (1972) Electroencephalogr Clin Neurophysiol , vol.32 , pp. 281-294
    • Racine, R.J.1
  • 77
    • 33645865872 scopus 로고    scopus 로고
    • Hippocampal neurodegeneration, spontaneous seizures, and mossy fiber sprouting in the F344 rat model of temporal lobe epilepsy
    • Rao MS, Hattiangady B, Reddy DS, Shetty AK (2006) Hippocampal neurodegeneration, spontaneous seizures, and mossy fiber sprouting in the F344 rat model of temporal lobe epilepsy. J Neurosci Res 83:1088-1105.
    • (2006) J Neurosci Res , vol.83 , pp. 1088-1105
    • Rao, M.S.1    Hattiangady, B.2    Reddy, D.S.3    Shetty, A.K.4
  • 78
    • 0037380708 scopus 로고    scopus 로고
    • Epilepsy after early-life seizures can be independent of hippocampal injury
    • DOI 10.1002/ana.10490
    • Raol VSH, Budreck EC, Brooks-Kayal AR (2003) Epilepsy after early-life seizures can be independent of hippocampal injury. Ann Neurol 53:503-511. (Pubitemid 36373262)
    • (2003) Annals of Neurology , vol.53 , Issue.4 , pp. 503-511
    • Raol, Y.S.H.1    Budreck, E.C.2    Brooks-Kayal, A.R.3
  • 79
    • 0027184309 scopus 로고
    • Epilepsy induced collateral sprouting of hippocampal mossy fibers: Does it induce the development of ectopic synapses with granule cell dendrites?
    • Represa A, Jorquera I, Le Gal La Salle G, Ben-Ari Y (1993) Epilepsy induced collateral sprouting of hippocampal mossy fibers: does it induce the development of ectopic synapses with granule cell dendrites? Hippocampus 3:257-268.
    • (1993) Hippocampus , vol.3 , pp. 257-268
    • Represa, A.1    Jorquera, I.2    Le Gal La Salle, G.3    Ben-Ari, Y.4
  • 80
    • 36249023723 scopus 로고    scopus 로고
    • Effects of rapamycin on gene expression, morphology, and electrophysiological properties of rat hippocampal neurons
    • DOI 10.1016/j.eplepsyres.2007.09.009, PII S0920121107002513
    • Rüegg S, Baybis M, Juul H, Dichter M, Crino PB (2007) Effects of rapamycin on gene expression, morphology, and electrophysiological properties of rat hippocampal neurons. Epilepsy Res 77:85-92. (Pubitemid 350137689)
    • (2007) Epilepsy Research , vol.77 , Issue.2-3 , pp. 85-92
    • Ruegg, S.1    Baybis, M.2    Juul, H.3    Dichter, M.4    Crino, P.B.5
  • 81
    • 16644368127 scopus 로고    scopus 로고
    • Role of mossy fiber sprouting and mossy cell loss in hyperexcitability: A network model of the dentate gyrus incorporating cell types and axonal topography
    • DOI 10.1152/jn.00777.2004
    • Santhakumar V, Aradi I, Soltesz I (2005) Role of mossy fiber sprouting and mossy cell loss in hyperexcitability: a network model of the dentate gyrus incorporating cell types and axonal topography. J Neurophysiol 93:437-453. (Pubitemid 40626852)
    • (2005) Journal of Neurophysiology , vol.93 , Issue.1 , pp. 437-453
    • Santhakumar, V.1    Aradi, I.2    Soltesz, I.3
  • 82
    • 0034663012 scopus 로고    scopus 로고
    • Granule-like neurons at the hilar/CA3 border after status epilepticus and their synchrony with area CA3 pyramidal cells: Functional implications of seizure-induced neurogenesis
    • Scharfman HE, Goodman JH, Sollas AL (2000) Granule-like neurons at the hilar/CA3 border after status epilepticus and their synchrony with area CA3 pyramidal cells: functional implications of seizure-induced neurogenesis. J Neurosci 20:6144-6158. (Pubitemid 30658408)
    • (2000) Journal of Neuroscience , vol.20 , Issue.16 , pp. 6144-6158
    • Scharfman, H.E.1    Goodman, J.H.2    Sollas, A.L.3
  • 83
    • 0142059006 scopus 로고    scopus 로고
    • Electrophysiological evidence of monosynaptic excitatory transmission between granule cells after seizure-induced mossy fiber sprouting
    • DOI 10.1152/jn.00251.2003
    • Scharfman HE, Sollas AL, Berger RE, Goodman JH (2003) Electrophysiological evidence of monosynaptic excitatory transmission between granule cells after seizure-induced mossy fiber sprouting. J Neurophysiol 90:2536-2547. (Pubitemid 37266522)
    • (2003) Journal of Neurophysiology , vol.90 , Issue.4 , pp. 2536-2547
    • Scharfman, H.E.1    Sollas, A.L.2    Berger, R.E.3    Goodman, J.H.4
  • 84
    • 0027655167 scopus 로고
    • Cycloheximide prevents kainate-induced neuronal death and c-fos expression in adult rat brain
    • Schreiber SS, Tocco G, Najm I, Thompson RF, Baudry M (1993) Cycloheximide prevents kainate-induced neuronal death and c-fos expression in adult rat brain. J Mol Neurosci 4:149-159.
    • (1993) J Mol Neurosci , vol.4 , pp. 149-159
    • Schreiber, S.S.1    Tocco, G.2    Najm, I.3    Thompson, R.F.4    Baudry, M.5
  • 85
    • 33846915925 scopus 로고    scopus 로고
    • Kainic acid induces early and transient autophagic stress in mouse hippocampus
    • DOI 10.1016/j.neulet.2006.12.025, PII S0304394006013140
    • Shacka JJ, Lu J, Xie Z-L, Uchiyama Y, Roth KA, Zhang J (2007) Kainic acid induces early and transient autophagic stress in mouse hippocampus. Neurosci Lett 414:57-60. (Pubitemid 46241649)
    • (2007) Neuroscience Letters , vol.414 , Issue.1 , pp. 57-60
    • Shacka, J.J.1    Lu, J.2    Xie, Z.-L.3    Uchiyama, Y.4    Roth, K.A.5    Zhang, J.6
  • 86
    • 29044448863 scopus 로고    scopus 로고
    • CA3 axonal sprouting in kainate-induced chronic epilepsy
    • DOI 10.1016/j.brainres.2005.10.066, PII S000689930501512X
    • Siddiqui AH, Joseph SA (2005) CA3 axonal sprouting in kainate-induced chronic epilepsy. Brain Res 1066:129-146. (Pubitemid 41790737)
    • (2005) Brain Research , vol.1066 , Issue.1-2 , pp. 129-146
    • Siddiqui, A.H.1    Joseph, S.A.2
  • 87
    • 0033821248 scopus 로고    scopus 로고
    • The role of mossy cell death and activation of protein synthesis in the sprouting of dentate mossy fibers: Evidence from calretinin and neo-Timm staining in pilocarpine-epileptic mice
    • Silva JG, Mello LEAM (2000) The role of mossy cell death and activation of protein synthesis in the sprouting of dentate mossy fibers: evidence from calretinin and neo-Timm staining in pilocarpine-epileptic mice. Epilepsia 41 [Suppl 6]:S18-S23.
    • (2000) Epilepsia , vol.41 , Issue.SUPPL. 6
    • Silva, J.G.1    Mello, L.E.A.M.2
  • 88
    • 0026594823 scopus 로고
    • Possible functional consequences of synaptic reorganization in the dentate gyrus of kainate-treated rats
    • Sloviter RS (1992) Possible functional consequences of synaptic reorganization in the dentate gyrus of kainate-treated rats. Neurosci Lett 137:91-96.
    • (1992) Neurosci Lett , vol.137 , pp. 91-96
    • Sloviter, R.S.1
  • 89
    • 0037459837 scopus 로고    scopus 로고
    • "Dormant basket cell" hypothesis revisited: Relative vulnerabilities of dentate gyrus mossy cells and inhibitory interneurons after hippocampal status epilepticus in the rat
    • DOI 10.1002/cne.10630
    • Sloviter RS, Zappone CA, Harvey BD, Bumanglag AV, Bender RA, Frotscher M (2003) "Dormant basket cell" hypothesis revisited: relative vulnerabilities of dentate gyrus mossy cells and inhibitory interneurons after hippocampal status epilepticus in the rat. J Comp Neurol 459:44-76. (Pubitemid 36348864)
    • (2003) Journal of Comparative Neurology , vol.459 , Issue.1 , pp. 44-76
    • Sloviter, R.S.1    Zappone, C.A.2    Harvey, B.D.3    Bumanglag, A.V.4    Bender, R.A.5    Frotscher, M.6
  • 90
    • 30344481350 scopus 로고    scopus 로고
    • Kainic acid-induced recurrent mossy fiber innervation of dentate gyrus inhibitory interneurons: Possible anatomical substrate of granule cell hyperinhibition in chronically epileptic rats
    • DOI 10.1002/cne.20850
    • Sloviter RS, Zappone CA, Harvey BD, Frotscher M (2006) Kainic acid-induced recurrent mossy fiber innervation of dentate gyrus inhibitory interneurons: possible anatomical substrate of granule cell hyperinhibition in chronically epileptic rats. J Comp Neurol 494:944-960. (Pubitemid 43063988)
    • (2006) Journal of Comparative Neurology , vol.494 , Issue.6 , pp. 944-960
    • Sloviter, R.S.1    Zappone, C.A.2    Harvey, B.D.3    Frotscher, M.4
  • 91
    • 0033046714 scopus 로고    scopus 로고
    • Differential neuronal and glial relations with parameters of ictal discharge in mesial temporal lobe epilepsy
    • DOI 10.1111/j.1528-1157.1999.tb00767.x
    • Spencer SS, Kim J, de Lanerolle N, Spencer DD (1999) Differential neuronal and glial relations with parameters of ictal discharge in mesial temporal lobe epilepsy. Epilepsia 40:708-712. (Pubitemid 29260708)
    • (1999) Epilepsia , vol.40 , Issue.6 , pp. 708-712
    • Spencer, S.S.1    Kim, J.2    DeLanerolle, N.3    Spencer, D.D.4
  • 92
    • 0024444281 scopus 로고
    • Mossy fiber synaptic reorganization in the epileptic human temporal lobe
    • Sutula T, Cascino G, Cavazos J, Parada I, Ramirez L (1989) Mossy fiber synaptic reorganization in the epileptic human temporal lobe. Ann Neurol 26:321-330. (Pubitemid 19230299)
    • (1989) Annals of Neurology , vol.26 , Issue.3 , pp. 321-330
    • Sutula, T.1    Cascino, G.2    Cavazos, J.3    Parada, I.4    Ramirez, L.5
  • 93
    • 0021917797 scopus 로고
    • Evidence of functional mossy fiber sprouting in hippocampal formation of kainic acid-treated rats
    • Tauck DL, Nadler JV (1985) Evidence of functional mossy fiber sprouting in hippocampal formation of kainic acid-treated rats. J Neurosci 5:1016-1022. (Pubitemid 15123049)
    • (1985) Journal of Neuroscience , vol.5 , Issue.4 , pp. 1016-1022
    • Tauck, D.L.1    Nadler, J.V.2
  • 94
    • 77649269555 scopus 로고    scopus 로고
    • Initial loss but later excess of GABAergic synapses with dentate granule cells in a rat model of temporal lobe epilepsy
    • Thind KK, Yamawaki R, Phanwar I, Zhang G, Wen X, Buckmaster PS (2010) Initial loss but later excess of GABAergic synapses with dentate granule cells in a rat model of temporal lobe epilepsy. J Comp Neurol 518:647-667.
    • (2010) J Comp Neurol , vol.518 , pp. 647-667
    • Thind, K.K.1    Yamawaki, R.2    Phanwar, I.3    Zhang, G.4    Wen, X.5    Buckmaster, P.S.6
  • 95
    • 0033003430 scopus 로고    scopus 로고
    • Dissociation of mossy fiber sprouting and electrically-induced seizure sensitivity: Rapid kindling versus adaptation
    • DOI 10.1016/S0920-1211(98)00078-3, PII S0920121198000783
    • Timofeeva OA, Peterson GM (1999) Dissociation of mossy fiber sprouting and electrically-induced seizure sensitivity: rapid kindling versus adaptation. Epilepsy Res 33:99-115. (Pubitemid 29143348)
    • (1999) Epilepsy Research , vol.33 , Issue.2-3 , pp. 99-115
    • Timofeeva, O.A.1    Peterson, G.M.2
  • 97
    • 12144254738 scopus 로고    scopus 로고
    • Axonal protein synthesis and degradation are necessary for efficient growth cone regeneration
    • DOI 10.1523/JNEUROSCI.3073-04.2005
    • Verma P, Chierzi S, Codd AM, Campbell DS, Meyer RL, Holt CE, Fawcett JW (2005) Axonal protein synthesis and degradation are necessary for efficient growth cone regeneration. J Neurosci 25:331-342. (Pubitemid 40105603)
    • (2005) Journal of Neuroscience , vol.25 , Issue.2 , pp. 331-342
    • Verma, P.1    Chierzi, S.2    Codd, A.M.3    Campbell, D.S.4    Meyer, R.L.5    Holt, C.E.6    Fawcett, J.W.7
  • 98
    • 63149114250 scopus 로고    scopus 로고
    • Loss of Tsc2 in radial glia models the brain pathology of tuberous sclerosis complex in the mouse
    • Way SW, McKenna J III, Mietzsch U, Reith RM, Wu HC, Gambello MJ (2009) Loss of Tsc2 in radial glia models the brain pathology of tuberous sclerosis complex in the mouse. Hum Mol Genet 18:1252-1265.
    • (2009) Hum Mol Genet , vol.18 , pp. 1252-1265
    • Way, S.W.1    McKenna III, J.2    Mietzsch, U.3    Reith, R.M.4    Wu, H.C.5    Gambello, M.J.6
  • 101
    • 0033935375 scopus 로고    scopus 로고
    • Kainic acid-induced mossy fiber sprouting and synapse formation in the dentate gyrus of rats
    • DOI 10.1002/1098-1063(2000)10:3<244::AID-HIPO5>3.0.CO;2-7
    • Wenzel HJ, Woolley CS, Robbins CA, Schwartzkroin PA (2000b) Kainic acid-induced mossy fiber sprouting and synapse formation in the dentate gyrus of rats. Hippocampus 10:244-260. (Pubitemid 30438660)
    • (2000) Hippocampus , vol.10 , Issue.3 , pp. 244-260
    • Wenzel, H.J.1    Woolley, C.S.2    Robbins, C.A.3    Schwartzkroin, P.A.4
  • 102
    • 0026339976 scopus 로고
    • Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator
    • West MJ, Slomianka L, Gundersen HJG (1991) Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator. Anat Rec 231:482-497.
    • (1991) Anat Rec , vol.231 , pp. 482-497
    • West, M.J.1    Slomianka, L.2    Gundersen, H.J.G.3
  • 103
    • 5344239006 scopus 로고    scopus 로고
    • Epilepsy and synaptic reorganization in a perinatal rat model of hypoxia-ischemia
    • DOI 10.1111/j.0013-9580.2004.60403.x
    • Williams PA, Dou P, Dudek FE (2004) Epilepsy and synaptic reorganization in a perinatal rat model of hypoxia-ischemia. Epilepsia 45:1210-1218. (Pubitemid 39350333)
    • (2004) Epilepsia , vol.45 , Issue.10 , pp. 1210-1218
    • Williams, P.A.1    Dou, P.2    Dudek, F.E.3
  • 105
    • 2142824184 scopus 로고    scopus 로고
    • Recurrent excitation in the dentate gyrus of a murine model of temporal lobe epilepsy
    • DOI 10.1016/j.eplepsyres.2004.01.002, PII S0920121104000245
    • Winokur RS, Kubal T, Liu D, Davis SF, Smith BN (2004) Recurrent excitation in the dentate gyrus of a murine model of temporal lobe epilepsy. Epilepsy Res 48:93-105. (Pubitemid 38553946)
    • (2004) Epilepsy Research , vol.58 , Issue.2-3 , pp. 93-105
    • Winokur, R.S.1    Kubal, T.2    Liu, D.3    Davis, S.F.4    Smith, B.N.5
  • 106
    • 0029937283 scopus 로고    scopus 로고
    • Electrographic seizures and new recurrent excitatory circuits in the dentate gyrus of hippocampal slices from kainate-treated epileptic rats
    • Wuarin J-P, Dudek FE (1996) Electrographic seizures and new recurrent excitatory circuits in the dentate gyrus of hippocampal slices from kainate-treated epileptic rats. J Neurosci 16:4438-4448. (Pubitemid 26243039)
    • (1996) Journal of Neuroscience , vol.16 , Issue.14 , pp. 4438-4448
    • Wuarin, J.-P.1    Dudek, F.E.2
  • 107
    • 0035096870 scopus 로고    scopus 로고
    • Excitatory synaptic input to granule cells increases with time after kainate treatment
    • Wuarin J-P, Dudek FE (2001) Excitatory synaptic input to granule cells increases with time after kainate treatment. J Neurophysiol 85:1067-1077. (Pubitemid 32209594)
    • (2001) Journal of Neurophysiology , vol.85 , Issue.3 , pp. 1067-1077
    • Wuarin, J.-P.1    Dudek, F.E.2
  • 108
    • 42949140259 scopus 로고    scopus 로고
    • Rapamycin prevents epilepsy in a mouse model of tuberous sclerosis complex
    • DOI 10.1002/ana.21331
    • Zeng L-H, Xu L, Gutmann DH, Wong M (2008) Rapamycin prevents epilepsy in a mouse model of tuberous sclerosis complex. Ann Neurol 63:444-453. (Pubitemid 351614710)
    • (2008) Annals of Neurology , vol.63 , Issue.4 , pp. 444-453
    • Zeng, L.-H.1    Xu, L.2    Gutmann, D.H.3    Wong, M.4
  • 109
    • 66149169973 scopus 로고    scopus 로고
    • The mammalian target of rapamycin signaling pathway mediates epileptogenesis in a model of temporal lobe epilepsy
    • Zeng L-H, Rensing NR, Wong M (2009) The mammalian target of rapamycin signaling pathway mediates epileptogenesis in a model of temporal lobe epilepsy. J Neurosci 29:6964-6972.
    • (2009) J Neurosci , vol.29 , pp. 6964-6972
    • Zeng, L.-H.1    Rensing, N.R.2    Wong, M.3
  • 110
    • 68149180641 scopus 로고    scopus 로고
    • Enhanced tonic GABA current in normotopic and hilar ectopic dentate granule cells after pilocarpine-induced status epilepticus
    • Zhan R-Z, Nadler JV (2009) Enhanced tonic GABA current in normotopic and hilar ectopic dentate granule cells after pilocarpine-induced status epilepticus. J Neurophysiol 102:670-681.
    • (2009) J Neurophysiol , vol.102 , pp. 670-681
    • Zhan, R.-Z.1    Nadler, J.V.2
  • 111
    • 0033594229 scopus 로고    scopus 로고
    • Ultrastructural localization of dynorphin in the dentate gyrus in human temporal lobe epilepsy: A study of reorganized mossy fiber synapses
    • Zhang N, Houser CR (1999) Ultrastructural localization of dynorphin in the dentate gyrus in human temporal lobe epilepsy: a study of reorganized mossy fiber synapses. J Comp Neurol 405:472-490. (Pubitemid 29124065)
    • (1999) Journal of Comparative Neurology , vol.405 , Issue.4 , pp. 472-490
    • Zhang, N.1    Houser, C.R.2
  • 112
    • 70449678682 scopus 로고    scopus 로고
    • Surviving hilar somatostatin interneurons enlarge, sprout axons, and form new synapses with granule cells in a mouse model of temporal lobe epilepsy
    • Zhang W, Yamawaki R, Wen X, Uhl J, Diaz J, Prince DA, Buckmaster PS (2009) Surviving hilar somatostatin interneurons enlarge, sprout axons, and form new synapses with granule cells in a mouse model of temporal lobe epilepsy. J Neurosci 29:14247-14256.
    • (2009) J Neurosci , vol.29 , pp. 14247-14256
    • Zhang, W.1    Yamawaki, R.2    Wen, X.3    Uhl, J.4    Diaz, J.5    Prince, D.A.6    Buckmaster, P.S.7
  • 114
    • 60849109211 scopus 로고    scopus 로고
    • Pharmacological inhibition of mTORC1 suppresses anatomical, cellular, and behavioral abnormalities in neural-specific Pten knockout mice
    • Zhou J, Blundell J, Ogawa S, Kwon C-H, Zhang W, Sinton C, Powell CM, Parada LF (2009) Pharmacological inhibition of mTORC1 suppresses anatomical, cellular, and behavioral abnormalities in neural-specific Pten knockout mice. J Neurosci 29:1773-1783.
    • (2009) J Neurosci , vol.29 , pp. 1773-1783
    • Zhou, J.1    Blundell, J.2    Ogawa, S.3    Kwon, C.-H.4    Zhang, W.5    Sinton, C.6    Powell, C.M.7    Parada, L.F.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.