Activation of mTOR signaling pathway is secondary to neuronal excitability in a mouse model of mesio-temporal lobe epilepsy

European Journal of Neuroscience

Volumn 41, Issue 7, 2015, Pages 974-986

  Shima, Ayako ^a,b   Nitta, Naoki ^a,c,d   Suzuki, Fumio ^b   Laharie, Anne Marie ^c,d   Nozaki, Kazuhiko ^a   Depaulis, Antoine ^c,d,e  

^a SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

^b Department of Neurosurgery   (Japan)

^c GRENOBLE INSTITUT DES NEUROSCIENCES   (France)

^d UNIV GRENOBLE ALPES   (France)

^e HÔPITAL MICHALLON   (France)

Author keywords

GABA; BDNF; Epileptogenesis; Granule cell dispersion; Mossy fiber sprouting

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; GLUTAMATE DECARBOXYLASE 67; MAMMALIAN TARGET OF RAPAMYCIN; S6 KINASE; CENTRAL NERVOUS SYSTEM AGENTS; KAINIC ACID; MIDAZOLAM; MTOR PROTEIN, MOUSE; RAPAMYCIN; TARGET OF RAPAMYCIN KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; BRAIN REGION; CELL LOSS; EPILEPTOGENESIS; FOCAL EPILEPSY; GLIOSIS; GRANULE CELL; HIPPOCAMPAL CA1 REGION; HIPPOCAMPAL CA3 REGION; HIPPOCAMPAL SCLEROSIS; IMMUNOREACTIVITY; INTERNEURON; MALE; MESIAL TEMPORAL LOBE EPILEPSY; MOUSE; NERVE CELL EXCITABILITY; NERVE CELL PLASTICITY; NERVE SPROUTING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PYRAMIDAL NERVE CELL; ANIMAL; C57BL MOUSE; DISEASE MODEL; DRUG EFFECTS; EPILEPSY, TEMPORAL LOBE; HIPPOCAMPUS; METABOLISM; NERVE CELL; NERVE CELL INHIBITION; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; ASTROCYTES; BRAIN-DERIVED NEUROTROPHIC FACTOR; CENTRAL NERVOUS SYSTEM AGENTS; DISEASE MODELS, ANIMAL; EPILEPSY, TEMPORAL LOBE; GLIOSIS; HIPPOCAMPUS; KAINIC ACID; MALE; MICE, INBRED C57BL; MIDAZOLAM; NEURAL INHIBITION; NEURONS; SIGNAL TRANSDUCTION; SIROLIMUS; TOR SERINE-THREONINE KINASES;

EID: 84926410419     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/ejn.12835     Document Type: Article

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