메뉴 건너뛰기




Volumn 13, Issue 1, 2016, Pages 49-70

Intracellular delivery of nanocarriers and targeting to subcellular organelles

Author keywords

cell penetrating peptides; cytoplasm; intracellular delivery; liposomes; macromolecules; mitochondria; nanocarriers; nuclei; polymeric micelles

Indexed keywords

DRUG CARRIER; LIGAND; NANOPARTICLE;

EID: 84955195063     PISSN: 17425247     EISSN: 17447593     Source Type: Journal    
DOI: 10.1517/17425247.2015.1086745     Document Type: Article
Times cited : (107)

References (165)
  • 1
    • 33748126226 scopus 로고    scopus 로고
    • Recent approaches to intracellular delivery of drugs and DNA and organelle targeting
    • Torchilin VP. Recent approaches to intracellular delivery of drugs and DNA and organelle targeting. Ann Rev Biomed Engineering 2006; 8: 343-75
    • (2006) Ann Rev Biomed Engineering , vol.8 , pp. 343-375
    • Torchilin, V.P.1
  • 2
    • 74049133619 scopus 로고    scopus 로고
    • Subcellular targeting strategies for drug design and delivery
    • Rajendran L, Knolker HJ, Simons K. Subcellular targeting strategies for drug design and delivery. Nat Rev Drug Discov 2010; 9 (1): 29-42
    • (2010) Nat Rev Drug Discov , vol.9 , Issue.1 , pp. 29-42
    • Rajendran, L.1    Knolker, H.J.2    Simons, K.3
  • 3
    • 75349103697 scopus 로고    scopus 로고
    • Subcellular targeting: A new frontier for drug-loaded pharmaceutical nanocarriers and the concept of the magic bullet
    • D'Souza GG, Weissig V. Subcellular targeting: a new frontier for drug-loaded pharmaceutical nanocarriers and the concept of the magic bullet. Exp Opin Drug Deliv 2009; 6 (11): 1135-48
    • (2009) Exp Opin Drug Deliv , vol.6 , Issue.11 , pp. 1135-1148
    • D'Souza, G.G.1    Weissig, V.2
  • 4
    • 84884819138 scopus 로고    scopus 로고
    • Reversing multidrug resistance by intracellular delivery of Pluronic(R) P85 unimers
    • Hong W, Chen D, Zhang X, et al. Reversing multidrug resistance by intracellular delivery of Pluronic(R) P85 unimers. Biomaterials 2013; 34 (37): 9602-14
    • (2013) Biomaterials , vol.34 , Issue.37 , pp. 9602-9614
    • Hong, W.1    Chen, D.2    Zhang, X.3
  • 6
    • 84858665557 scopus 로고    scopus 로고
    • Endocytosis at the nanoscale
    • Canton I, Battaglia G. Endocytosis at the nanoscale. Chem Soc Rev 2012; 41 (7): 2718-39
    • (2012) Chem Soc Rev , vol.41 , Issue.7 , pp. 2718-2739
    • Canton, I.1    Battaglia, G.2
  • 7
    • 84865967844 scopus 로고    scopus 로고
    • Endocytosis and intracellular trafficking as gateways for nanomedicine delivery: Opportunities and challenges
    • Duncan R, Richardson SC. Endocytosis and intracellular trafficking as gateways for nanomedicine delivery: opportunities and challenges. Mol Pharm 2012; 9 (9): 2380-402
    • (2012) Mol Pharm , vol.9 , Issue.9 , pp. 2380-2402
    • Duncan, R.1    Richardson, S.C.2
  • 8
    • 0037422066 scopus 로고    scopus 로고
    • Regulated portals of entry into the cell
    • Conner SD, Schmid SL. Regulated portals of entry into the cell. Nature 2003; 422 (6927): 37-44
    • (2003) Nature , vol.422 , Issue.6927 , pp. 37-44
    • Conner, S.D.1    Schmid, S.L.2
  • 10
    • 84893816004 scopus 로고    scopus 로고
    • Endosomal escape: A bottleneck in intracellular delivery
    • Shete HK, Prabhu RH, Patravale VB. Endosomal escape: a bottleneck in intracellular delivery. J Nanosci Nanotechnol 2014; 14 (1): 460-74
    • (2014) J Nanosci Nanotechnol , vol.14 , Issue.1 , pp. 460-474
    • Shete, H.K.1    Prabhu, R.H.2    Patravale, V.B.3
  • 11
    • 79957460418 scopus 로고    scopus 로고
    • Endosomal escape pathways for delivery of biologicals
    • Varkouhi AK, Scholte M, Storm G, et al. Endosomal escape pathways for delivery of biologicals. J Controlled Release 2011; 151 (3): 220-8
    • (2011) J Controlled Release , vol.151 , Issue.3 , pp. 220-228
    • Varkouhi, A.K.1    Scholte, M.2    Storm, G.3
  • 12
    • 84883290732 scopus 로고    scopus 로고
    • Microfluidic electroporation for cellular analysis and delivery
    • Geng T, Lu C. Microfluidic electroporation for cellular analysis and delivery. Lab Chip 2013; 13 (19): 3803-21
    • (2013) Lab Chip , vol.13 , Issue.19 , pp. 3803-3821
    • Geng, T.1    Lu, C.2
  • 13
    • 84883306486 scopus 로고    scopus 로고
    • Bombarding cancer: Biolistic delivery of therapeutics using porous Si carriers
    • Zilony N, Tzur-Balter A, Segal E, et al. Bombarding cancer: biolistic delivery of therapeutics using porous Si carriers. Scientific Rep 2013; 3: 2499
    • (2013) Scientific Rep , vol.3 , pp. 2499
    • Zilony, N.1    Tzur-Balter, A.2    Segal, E.3
  • 14
    • 84890501693 scopus 로고    scopus 로고
    • Interleukin-27 gene delivery for modifying malignant interactions between prostate tumor and bone
    • Zolochevska O, Ellis J, Parelkar S, et al. Interleukin-27 gene delivery for modifying malignant interactions between prostate tumor and bone. Hum Gene Ther 2013; 24 (12): 970-81
    • (2013) Hum Gene Ther , vol.24 , Issue.12 , pp. 970-981
    • Zolochevska, O.1    Ellis, J.2    Parelkar, S.3
  • 15
    • 84901030049 scopus 로고    scopus 로고
    • Multifunctional polymeric micelles for delivery of drugs and siRNA
    • Jhaveri AM, Torchilin VP. Multifunctional polymeric micelles for delivery of drugs and siRNA. Front Pharmacol 2014; 5: 77
    • (2014) Front Pharmacol , vol.5 , pp. 77
    • Jhaveri, A.M.1    Torchilin, V.P.2
  • 16
    • 34249820576 scopus 로고    scopus 로고
    • Multifunctional nanocarriers
    • Torchilin VP. Multifunctional nanocarriers. Advanced Drug Deliv Rev 2006; 58 (14): 1532-55
    • (2006) Advanced Drug Deliv Rev , vol.58 , Issue.14 , pp. 1532-1555
    • Torchilin, V.P.1
  • 17
    • 1642575957 scopus 로고    scopus 로고
    • Size-dependent internalization of particles via the pathways of clathrin-And caveolae-mediated endocytosis
    • Rejman J, Oberle V, Zuhorn IS, et al. Size-dependent internalization of particles via the pathways of clathrin-And caveolae-mediated endocytosis. Biochem J 2004; 377 (Pt 1): 159-69
    • (2004) Biochem J , vol.377 , pp. 159-169
    • Rejman, J.1    Oberle, V.2    Zuhorn, I.S.3
  • 18
    • 51049092308 scopus 로고    scopus 로고
    • Factors affecting the clearance and biodistribution of polymeric nanoparticles
    • Alexis F, Pridgen E, Molnar LK, et al. Factors affecting the clearance and biodistribution of polymeric nanoparticles. Mol Pharm 2008; 5 (4): 505-15
    • (2008) Mol Pharm , vol.5 , Issue.4 , pp. 505-515
    • Alexis, F.1    Pridgen, E.2    Molnar, L.K.3
  • 19
    • 0028470454 scopus 로고
    • Barriers to drug delivery in solid tumors
    • Jain RK. Barriers to drug delivery in solid tumors. Scientific Am 1994; 271 (1): 58-65
    • (1994) Scientific Am , vol.271 , Issue.1 , pp. 58-65
    • Jain, R.K.1
  • 20
    • 0023481357 scopus 로고
    • Transport of molecules across tumor vasculature
    • Jain RK. Transport of molecules across tumor vasculature. Cancer Metastat Rev 1987; 6 (4): 559-93
    • (1987) Cancer Metastat Rev , vol.6 , Issue.4 , pp. 559-593
    • Jain, R.K.1
  • 21
    • 0032516078 scopus 로고    scopus 로고
    • Regulation of transport pathways in tumor vessels: Role of tumor type and microenvironment
    • Hobbs SK, Monsky WL, Yuan F, et al. Regulation of transport pathways in tumor vessels: role of tumor type and microenvironment. Proc Natl Acad Sci USA 1998; 95 (8): 4607-12
    • (1998) Proc Natl Acad Sci USA , vol.95 , Issue.8 , pp. 4607-4612
    • Hobbs, S.K.1    Monsky, W.L.2    Yuan, F.3
  • 22
    • 0022858683 scopus 로고
    • A new concept for macromolecular therapeutics in cancer chemotherapy: Mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs
    • Matsumura Y, Maeda H. A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs. Cancer Res 1986; 46 (12 Pt 1): 6387-92
    • (1986) Cancer Res , vol.46 , Issue.12 , pp. 6387-6392
    • Matsumura, Y.1    Maeda, H.2
  • 23
    • 0032879653 scopus 로고    scopus 로고
    • Size-dependent extravasation and interstitial localization of polyethyleneglycol liposomes in solid tumor-bearing mice
    • Ishida O, Maruyama K, Sasaki K, et al. Size-dependent extravasation and interstitial localization of polyethyleneglycol liposomes in solid tumor-bearing mice. Int J Pharm 1999; 190 (1): 49-56
    • (1999) Int J Pharm , vol.190 , Issue.1 , pp. 49-56
    • Ishida, O.1    Maruyama, K.2    Sasaki, K.3
  • 24
    • 77955175216 scopus 로고    scopus 로고
    • Strategies in the design of nanoparticles for therapeutic applications
    • Petros RA, DeSimone JM. Strategies in the design of nanoparticles for therapeutic applications. Nat Rev Drug Discov 2010; 9 (8): 615-27
    • (2010) Nat Rev Drug Discov , vol.9 , Issue.8 , pp. 615-627
    • Petros, R.A.1    DeSimone, J.M.2
  • 25
    • 28844488494 scopus 로고    scopus 로고
    • Opsonization, biodistribution, and pharmacokinetics of polymeric nanoparticles
    • Owens DE, Peppas NA. Opsonization, biodistribution, and pharmacokinetics of polymeric nanoparticles. Int J Pharm 2006; 307 (1): 93-102
    • (2006) Int J Pharm , vol.307 , Issue.1 , pp. 93-102
    • Owens, D.E.1    Peppas, N.A.2
  • 26
    • 23444444512 scopus 로고
    • Biodegradable long-circulating polymeric nanospheres
    • Gref R, Minamitake Y, Peracchia MT, et al. Biodegradable long-circulating polymeric nanospheres. Science 1994; 263 (5153): 1600-3
    • (1994) Science , vol.263 , Issue.5153 , pp. 1600-1603
    • Gref, R.1    Minamitake, Y.2    Peracchia, M.T.3
  • 27
    • 79953066932 scopus 로고    scopus 로고
    • A multifunctional envelope type nano device (MEND) for gene delivery to tumours based on the EPR effect: A strategy for overcoming the PEG dilemma
    • Hatakeyama H, Akita H, Harashima H. A multifunctional envelope type nano device (MEND) for gene delivery to tumours based on the EPR effect: a strategy for overcoming the PEG dilemma. Advanced Drug Deliv Rev 2011; 63 (3): 152-60
    • (2011) Advanced Drug Deliv Rev , vol.63 , Issue.3 , pp. 152-160
    • Hatakeyama, H.1    Akita, H.2    Harashima, H.3
  • 28
    • 84891821723 scopus 로고    scopus 로고
    • Doxorubicin in TAT peptide-modified multifunctional immunoliposomes demonstrates increased activity against both drug-sensitive and drug-resistant ovarian cancer models
    • Apte A, Koren E, Koshkaryev A, et al. Doxorubicin in TAT peptide-modified multifunctional immunoliposomes demonstrates increased activity against both drug-sensitive and drug-resistant ovarian cancer models. Cancer Biol Ther 2014; 15 (1): 69-80
    • (2014) Cancer Biol Ther , vol.15 , Issue.1 , pp. 69-80
    • Apte, A.1    Koren, E.2    Koshkaryev, A.3
  • 29
    • 84887346589 scopus 로고    scopus 로고
    • Active targeting of block copolymer micelles with trastuzumab Fab fragments and nuclear localization signal leads to increased tumor uptake and nuclear localization in HER2-overexpressing xenografts
    • Hoang B, Ekdawi SN, Reilly RM, et al. Active targeting of block copolymer micelles with trastuzumab Fab fragments and nuclear localization signal leads to increased tumor uptake and nuclear localization in HER2-overexpressing xenografts. Mol Pharm 2013; 10 (11): 4229-41
    • (2013) Mol Pharm , vol.10 , Issue.11 , pp. 4229-4241
    • Hoang, B.1    Ekdawi, S.N.2    Reilly, R.M.3
  • 30
    • 84885381042 scopus 로고    scopus 로고
    • Intracellular observation of nanocarriers modified with a mitochondrial targeting signal peptide
    • Kawamura E, Yamada Y, Yasuzaki Y, et al. Intracellular observation of nanocarriers modified with a mitochondrial targeting signal peptide. J Biosci Bioengn 2013; 116 (5): 634-7
    • (2013) J Biosci Bioengn , vol.116 , Issue.5 , pp. 634-637
    • Kawamura, E.1    Yamada, Y.2    Yasuzaki, Y.3
  • 31
    • 34548591713 scopus 로고    scopus 로고
    • Efficient generation of antigen-specific cellular immunity by vaccination with poly(γ-glutamic acid) nanoparticles entrapping endoplasmic reticulum-Targeted peptides
    • Matsuo K, Yoshikawa T, Oda A, et al. Efficient generation of antigen-specific cellular immunity by vaccination with poly(γ-glutamic acid) nanoparticles entrapping endoplasmic reticulum-Targeted peptides. Biochem Biophys Res Commun 2007; 362 (4): 1069-72
    • (2007) Biochem Biophys Res Commun , vol.362 , Issue.4 , pp. 1069-1072
    • Matsuo, K.1    Yoshikawa, T.2    Oda, A.3
  • 32
    • 79960550642 scopus 로고    scopus 로고
    • Surface modification of liposomes with rhodamine-123-conjugated polymer results in enhanced mitochondrial targeting
    • Biswas S, Dodwadkar NS, Sawant RR, et al. Surface modification of liposomes with rhodamine-123-conjugated polymer results in enhanced mitochondrial targeting. J Drug Targeting 2011; 19 (7): 552-61
    • (2011) J Drug Targeting , vol.19 , Issue.7 , pp. 552-561
    • Biswas, S.1    Dodwadkar, N.S.2    Sawant, R.R.3
  • 33
    • 84878451456 scopus 로고    scopus 로고
    • Octa-Arginine-modified pegylated liposomal doxorubicin: An effective treatment strategy for non-small cell lung cancer
    • Biswas S, Deshpande PP, Perche F, et al. Octa-Arginine-modified pegylated liposomal doxorubicin: an effective treatment strategy for non-small cell lung cancer. Cancer Lett 2013; 335 (1): 191-200
    • (2013) Cancer Lett , vol.335 , Issue.1 , pp. 191-200
    • Biswas, S.1    Deshpande, P.P.2    Perche, F.3
  • 34
    • 78650379518 scopus 로고    scopus 로고
    • Strategies for the intracellular delivery of nanoparticles
    • Chou LY, Ming K, Chan WC. Strategies for the intracellular delivery of nanoparticles. Chem Soc Rev 2011; 40 (1): 233-45
    • (2011) Chem Soc Rev , vol.40 , Issue.1 , pp. 233-245
    • Chou, L.Y.1    Ming, K.2    Chan, W.C.3
  • 35
    • 34548267667 scopus 로고    scopus 로고
    • Endocytic mechanisms for targeted drug delivery
    • Bareford LM, Swaan PW. Endocytic mechanisms for targeted drug delivery. Advanced Drug Deliv Rev 2007; 59 (8): 748-58
    • (2007) Advanced Drug Deliv Rev , vol.59 , Issue.8 , pp. 748-758
    • Bareford, L.M.1    Swaan, P.W.2
  • 37
    • 0022517619 scopus 로고
    • Receptor-mediated endocytosis: The intracellular journey of transferrin and its receptor
    • Dautry-Varsat A. Receptor-mediated endocytosis: the intracellular journey of transferrin and its receptor. Biochimie 1986; 68 (3): 375-81
    • (1986) Biochimie , vol.68 , Issue.3 , pp. 375-381
    • Dautry-Varsat, A.1
  • 38
    • 50849144942 scopus 로고    scopus 로고
    • Cell penetrating peptide-modified pharmaceutical nanocarriers for intracellular drug and gene delivery
    • Torchilin VP. Cell penetrating peptide-modified pharmaceutical nanocarriers for intracellular drug and gene delivery. Biopolymers 2008; 90 (5): 604-10
    • (2008) Biopolymers , vol.90 , Issue.5 , pp. 604-610
    • Torchilin, V.P.1
  • 39
    • 84955201275 scopus 로고    scopus 로고
    • Intracellular delivery of nanoparticles with cpps
    • In: Langel Ü editor. Second Edition. CRC/Taylor&Francis, Boca Raton
    • Gupta B, Torchilin VP. Intracellular Delivery of Nanoparticles with CPPs. In: Langel Ü.,. editor. Handbook of Cell-Penetrating Peptides. Second Edition. CRC/Taylor&Francis, Boca Raton; 2006. p. 439-54
    • (2006) Handbook of Cell-Penetrating Peptides , pp. 439-454
    • Gupta, B.1    Torchilin, V.P.2
  • 40
    • 2642680830 scopus 로고    scopus 로고
    • Cell penetration by transportan
    • Pooga M, Hallbrink M, Zorko M, et al. Cell penetration by transportan. FASEB 1998; 12 (1): 67-77
    • (1998) FASEB , vol.12 , Issue.1 , pp. 67-77
    • Pooga, M.1    Hallbrink, M.2    Zorko, M.3
  • 41
    • 0031471203 scopus 로고    scopus 로고
    • Intercellular trafficking and protein delivery by a herpesvirus structural protein
    • Elliott G, OHare P. Intercellular trafficking and protein delivery by a herpesvirus structural protein. Cell 1997; 88 (2): 223-33
    • (1997) Cell , vol.88 , Issue.2 , pp. 223-233
    • Elliott, G.1    O'Hare, P.2
  • 42
    • 0032508926 scopus 로고    scopus 로고
    • Cellular uptake of an alpha-helical amphipathic model peptide with the potential to deliver polar compounds into the cell interior non-endocytically
    • Oehlke J, Scheller A, Wiesner B, et al. Cellular uptake of an alpha-helical amphipathic model peptide with the potential to deliver polar compounds into the cell interior non-endocytically. Biochim Biophys Acta 1998; 1414 (1-2): 127-39
    • (1998) Biochim Biophys Acta , vol.1414 , Issue.12 , pp. 127-139
    • Oehlke, J.1    Scheller, A.2    Wiesner, B.3
  • 43
    • 0035937124 scopus 로고    scopus 로고
    • Arginine-rich peptides. An abundant source of membrane-permeable peptides having potential as carriers for intracellular protein delivery
    • Futaki S, Suzuki T, Ohashi W, et al. Arginine-rich peptides. An abundant source of membrane-permeable peptides having potential as carriers for intracellular protein delivery. J Biol Chem 2001; 276 (8): 5836-40
    • (2001) J Biol Chem , vol.276 , Issue.8 , pp. 5836-5840
    • Futaki, S.1    Suzuki, T.2    Ohashi, W.3
  • 44
    • 84863099046 scopus 로고    scopus 로고
    • Cell-penetrating peptides: Breaking through to the other side
    • Koren E, Torchilin VP. Cell-penetrating peptides: breaking through to the other side. Trends Mol Med 2012; 18 (7): 385-93
    • (2012) Trends Mol Med , vol.18 , Issue.7 , pp. 385-393
    • Koren, E.1    Torchilin, V.P.2
  • 45
    • 84889970066 scopus 로고    scopus 로고
    • Recent progress of cell-penetrating peptides as new carriers for intracellular cargo delivery
    • Wang F, Wang Y, Zhang X, et al. Recent progress of cell-penetrating peptides as new carriers for intracellular cargo delivery. J Controlled Release 2014; 174: 126-36
    • (2014) J Controlled Release , vol.174 , pp. 126-136
    • Wang, F.1    Wang, Y.2    Zhang, X.3
  • 46
    • 84896830779 scopus 로고    scopus 로고
    • In vitro transfection of bone marrow-derived dendritic cells with TATp-liposomes
    • Pappalardo JS, Langellotti CA, Di Giacomo S, et al. In vitro transfection of bone marrow-derived dendritic cells with TATp-liposomes. Int J Nanomed 2014; 9: 963-73
    • (2014) Int J Nanomed , vol.9 , pp. 963-973
    • Pappalardo, J.S.1    Langellotti, C.A.2    Di Giacomo, S.3
  • 47
    • 84885716472 scopus 로고    scopus 로고
    • Enhanced anticancer activity of nanopreparation containing an MMP2-sensitive PEG-drug conjugate and cell-penetrating moiety
    • Zhu L, Wang T, Perche F, et al. Enhanced anticancer activity of nanopreparation containing an MMP2-sensitive PEG-drug conjugate and cell-penetrating moiety. Proc Natl Acad Sci USA 2013; 110 (42): 17047-
    • (2013) Proc Natl Acad Sci USA , vol.110 , Issue.42 , pp. 17047
    • Zhu, L.1    Wang, T.2    Perche, F.3
  • 48
    • 84861670821 scopus 로고    scopus 로고
    • Multifunctional PEGylated 2C5-immunoliposomes containing pH-sensitive bonds and TAT peptide for enhanced tumor cell internalization and cytotoxicity
    • Koren E, Apte A, Jani A, et al. Multifunctional PEGylated 2C5-immunoliposomes containing pH-sensitive bonds and TAT peptide for enhanced tumor cell internalization and cytotoxicity. J Controlled Release 2012; 160 (2): 264-73
    • (2012) J Controlled Release , vol.160 , Issue.2 , pp. 264-273
    • Koren, E.1    Apte, A.2    Jani, A.3
  • 49
    • 25444484384 scopus 로고    scopus 로고
    • Protamine as an efficient membrane-Translocating peptide
    • Reynolds F, Weissleder R, Josephson L. Protamine as an efficient membrane-Translocating peptide. Bioconjugate Chem 2005; 16 (5): 1240-5
    • (2005) Bioconjugate Chem , vol.16 , Issue.5 , pp. 1240-1245
    • Reynolds, F.1    Weissleder, R.2    Josephson, L.3
  • 50
    • 84870716717 scopus 로고    scopus 로고
    • Structure and dynamics of the two amphipathic arginine-rich peptides RW9 and RL9 in a lipid environment investigated by solid-state NMR and MD simulations
    • Witte K, Olausson BE, Walrant A, et al. Structure and dynamics of the two amphipathic arginine-rich peptides RW9 and RL9 in a lipid environment investigated by solid-state NMR and MD simulations. Biochim Biophys Acta 2013; 1828 (2): 824-33
    • (2013) Biochim Biophys Acta , vol.1828 , Issue.2 , pp. 824-833
    • Witte, K.1    Olausson, B.E.2    Walrant, A.3
  • 51
    • 67650607435 scopus 로고    scopus 로고
    • Multifunctional prenylated peptides for live cell analysis
    • Wollack JW, Zeliadt NA, Mullen DG, et al. Multifunctional prenylated peptides for live cell analysis. J Am Chem Soc 2009; 131 (21): 7293-303
    • (2009) J Am Chem Soc , vol.131 , Issue.21 , pp. 7293-7303
    • Wollack, J.W.1    Zeliadt, N.A.2    Mullen, D.G.3
  • 52
    • 84857478229 scopus 로고    scopus 로고
    • Targeting CXCR4 with cell-penetrating pepducins in lymphoma and lymphocytic leukemia
    • OCallaghan K, Lee L, Nguyen N, et al. Targeting CXCR4 with cell-penetrating pepducins in lymphoma and lymphocytic leukemia. Blood 2012; 119 (7): 1717-25
    • (2012) Blood , vol.119 , Issue.7 , pp. 1717-1725
    • O'Callaghan, K.1    Lee, L.2    Nguyen, N.3
  • 53
    • 0029999551 scopus 로고    scopus 로고
    • Identification of a functionally important sequence in the cytoplasmic tail of integrin beta 3 by using cell-permeable peptide analogs
    • Liu XY, Timmons S, Lin YZ, et al. Identification of a functionally important sequence in the cytoplasmic tail of integrin beta 3 by using cell-permeable peptide analogs. Proc Natl Acad Sci USA 1996; 93 (21): 11819-24
    • (1996) Proc Natl Acad Sci USA , vol.93 , Issue.21 , pp. 11819-11824
    • Liu, X.Y.1    Timmons, S.2    Lin, Y.Z.3
  • 54
    • 20444403719 scopus 로고    scopus 로고
    • Effects of cargo molecules on the cellular uptake of arginine-rich cell-penetrating peptides
    • Maiolo JR, Ferrer M, Ottinger EA. Effects of cargo molecules on the cellular uptake of arginine-rich cell-penetrating peptides. Biochim Biophys Acta 2005; 1712 (2): 161-72
    • (2005) Biochim Biophys Acta , vol.1712 , Issue.2 , pp. 161-172
    • Maiolo, J.R.1    Ferrer, M.2    Ottinger, E.A.3
  • 55
    • 58149099412 scopus 로고    scopus 로고
    • Comparison of cellular uptake using 22 CPPs in 4 different cell lines
    • Mueller J, Kretzschmar I, Volkmer R, et al. Comparison of cellular uptake using 22 CPPs in 4 different cell lines. Bioconjugate Chem 2008; 19 (12): 2363-74
    • (2008) Bioconjugate Chem , vol.19 , Issue.12 , pp. 2363-2374
    • Mueller, J.1    Kretzschmar, I.2    Volkmer, R.3
  • 56
    • 28444464129 scopus 로고    scopus 로고
    • Membrane surface-Associated helices promote lipid interactions and cellular uptake of human calcitonin-derived cell penetrating peptides
    • Herbig ME, Weller K, Krauss U, et al. Membrane surface-Associated helices promote lipid interactions and cellular uptake of human calcitonin-derived cell penetrating peptides. Biophys J 2005; 89 (6): 4056-66
    • (2005) Biophys J , vol.89 , Issue.6 , pp. 4056-4066
    • Herbig, M.E.1    Weller, K.2    Krauss, U.3
  • 57
    • 38949192863 scopus 로고    scopus 로고
    • Tat peptide-mediated intracellular delivery of pharmaceutical nanocarriers
    • Torchilin VP. Tat peptide-mediated intracellular delivery of pharmaceutical nanocarriers. Advanced Drug Deliv Rev 2008; 60 (4-5): 548-58
    • (2008) Advanced Drug Deliv Rev , vol.60 , Issue.45 , pp. 548-558
    • Torchilin, V.P.1
  • 58
    • 84862618219 scopus 로고    scopus 로고
    • SiRNA and pharmacological inhibition of endocytic pathways to characterize the differential role of macropinocytosis and the actin cytoskeleton on cellular uptake of dextran and cationic cell penetrating peptides octaarginine (R8) and HIV-Tat
    • Al Soraj M, He L, Peynshaert K, et al. siRNA and pharmacological inhibition of endocytic pathways to characterize the differential role of macropinocytosis and the actin cytoskeleton on cellular uptake of dextran and cationic cell penetrating peptides octaarginine (R8) and HIV-Tat. J Controlled Release 2012; 161 (1): 132-41
    • (2012) J Controlled Release , vol.161 , Issue.1 , pp. 132-141
    • Al Soraj, M.1    He, L.2    Peynshaert, K.3
  • 59
    • 84855733169 scopus 로고    scopus 로고
    • The role of endocytosis on the uptake kinetics of luciferin-conjugated cell-penetrating peptides
    • Mager I, Langel K, Lehto T, et al. The role of endocytosis on the uptake kinetics of luciferin-conjugated cell-penetrating peptides. Biochim Biophys Acta 2012; 1818 (3): 502-11
    • (2012) Biochim Biophys Acta , vol.1818 , Issue.3 , pp. 502-511
    • Mager, I.1    Langel, K.2    Lehto, T.3
  • 60
    • 84891351398 scopus 로고    scopus 로고
    • Internalization routes of cell-penetrating melanoma antigen peptides into human dendritic cells
    • Buhl T, Braun A, Forkel S, et al. Internalization routes of cell-penetrating melanoma antigen peptides into human dendritic cells. Exp Dermatol 2014; 23 (1): 20-6
    • (2014) Exp Dermatol , vol.23 , Issue.1 , pp. 20-26
    • Buhl, T.1    Braun, A.2    Forkel, S.3
  • 61
    • 84871325412 scopus 로고    scopus 로고
    • Cellular internalization mechanism and intracellular trafficking of filamentous M13 phages displaying a cell-penetrating transbody and TAT peptide
    • Kim A, Shin TH, Shin SM, et al. Cellular internalization mechanism and intracellular trafficking of filamentous M13 phages displaying a cell-penetrating transbody and TAT peptide. PLoS One 2012; 7 (12): e51813
    • (2012) PLoS One , vol.7 , Issue.12 , pp. e51813
    • Kim, A.1    Shin, T.H.2    Shin, S.M.3
  • 62
    • 84901343834 scopus 로고    scopus 로고
    • Cell penetrating peptides: Efficient vectors for delivery of nanoparticles, nanocarriers, therapeutic and diagnostic molecules
    • Epub ahead of print]
    • Farkhani SM, Valizadeh A, Karami H, et al. Cell penetrating peptides: Efficient vectors for delivery of nanoparticles, nanocarriers, therapeutic and diagnostic molecules. Peptides 2014. [Epub ahead of print]
    • (2014) Peptides
    • Farkhani, S.M.1    Valizadeh, A.2    Karami, H.3
  • 63
    • 77749297971 scopus 로고    scopus 로고
    • Activatable cell penetrating peptides linked to nanoparticles as dual probes for in vivo fluorescence and MR imaging of proteases
    • Olson ES, Jiang T, Aguilera TA, et al. Activatable cell penetrating peptides linked to nanoparticles as dual probes for in vivo fluorescence and MR imaging of proteases. Proc Natl Acad Sci USA 2010; 107 (9): 4311-16
    • (2010) Proc Natl Acad Sci USA , vol.107 , Issue.9 , pp. 4311-4316
    • Olson, E.S.1    Jiang, T.2    Aguilera, T.A.3
  • 64
    • 84879116229 scopus 로고    scopus 로고
    • Surface functionalization of doxorubicin-loaded liposomes with octa-Arginine for enhanced anticancer activity
    • Biswas S, Dodwadkar NS, Deshpande PP, et al. Surface functionalization of doxorubicin-loaded liposomes with octa-Arginine for enhanced anticancer activity. Eur J Pharm Biopharm 2013; 84 (3): 517-25
    • (2013) Eur J Pharm Biopharm , vol.84 , Issue.3 , pp. 517-525
    • Biswas, S.1    Dodwadkar, N.S.2    Deshpande, P.P.3
  • 65
    • 84879588579 scopus 로고    scopus 로고
    • Synthesis, characterization and applications of carboxylated and polyethylene-glycolated bifunctionalized InP/ZnS quantum dots in cellular internalization mediated by cell-penetrating peptides
    • Liu BR, Winiarz JG, Moon JS, et al. Synthesis, characterization and applications of carboxylated and polyethylene-glycolated bifunctionalized InP/ZnS quantum dots in cellular internalization mediated by cell-penetrating peptides. Colloids and surfaces B, Biointerfaces 2013; 111C: 162-70
    • (2013) Colloids and Surfaces B, Biointerfaces , vol.111 C , pp. 162-170
    • Liu, B.R.1    Winiarz, J.G.2    Moon, J.S.3
  • 66
    • 84871652149 scopus 로고    scopus 로고
    • Harnessing the power of cell-penetrating peptides: Activatable carriers for targeting systemic delivery of cancer therapeutics and imaging agents
    • MacEwan SR, Chilkoti A. Harnessing the power of cell-penetrating peptides: activatable carriers for targeting systemic delivery of cancer therapeutics and imaging agents. Wiley Interdisciplinary Rev Nanomed Nanobiotechnol 2013; 5 (1): 31-48
    • (2013) Wiley Interdisciplinary Rev Nanomed Nanobiotechnol , vol.5 , Issue.1 , pp. 31-48
    • MacEwan, S.R.1    Chilkoti, A.2
  • 67
    • 47349097049 scopus 로고    scopus 로고
    • Super pH-sensitive multifunctional polymeric micelle for tumor pH(e) specific TAT exposure and multidrug resistance
    • Lee ES, Gao Z, Kim D, et al. Super pH-sensitive multifunctional polymeric micelle for tumor pH(e) specific TAT exposure and multidrug resistance. J Controlled Release 2008; 129 (3): 228-36
    • (2008) J Controlled Release , vol.129 , Issue.3 , pp. 228-236
    • Lee, E.S.1    Gao, Z.2    Kim, D.3
  • 68
    • 79960598683 scopus 로고    scopus 로고
    • Design of acid-Activated cell penetrating peptide for delivery of active molecules into cancer cells
    • Zhang W, Song J, Zhang B, et al. Design of acid-Activated cell penetrating peptide for delivery of active molecules into cancer cells. Bioconjugate Chem 2011; 22 (7): 1410-15
    • (2011) Bioconjugate Chem , vol.22 , Issue.7 , pp. 1410-1415
    • Zhang, W.1    Song, J.2    Zhang, B.3
  • 69
    • 58549107779 scopus 로고    scopus 로고
    • Development of an optimized activatable MMP-14 targeted SPECT imaging probe
    • Watkins GA, Jones EF, Scott Shell M, et al. Development of an optimized activatable MMP-14 targeted SPECT imaging probe. Bioorganic Med Chem 2009; 17 (2): 653-9
    • (2009) Bioorganic Med Chem , vol.17 , Issue.2 , pp. 653-659
    • Watkins, G.A.1    Jones, E.F.2    Scott Shell, M.3
  • 70
    • 84862277231 scopus 로고    scopus 로고
    • Digital switching of local arginine density in a genetically encoded self-Assembled polypeptide nanoparticle controls cellular uptake
    • Macewan SR, Chilkoti A. Digital switching of local arginine density in a genetically encoded self-Assembled polypeptide nanoparticle controls cellular uptake. Nano Lett 2012; 12 (6): 3322-8
    • (2012) Nano Lett , vol.12 , Issue.6 , pp. 3322-3328
    • Macewan, S.R.1    Chilkoti, A.2
  • 71
    • 0029160083 scopus 로고
    • A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: Polyethylenimine
    • Boussif O, Lezoualch F, Zanta MA, et al. A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine. Proc Natl Acad Sci USA 1995; 92 (16): 7297-301
    • (1995) Proc Natl Acad Sci USA , vol.92 , Issue.16 , pp. 7297-7301
    • Boussif, O.1    Lezoualch, F.2    Zanta, M.A.3
  • 72
    • 78650476432 scopus 로고    scopus 로고
    • The proton sponge: A trick to enter cells the viruses did not exploit
    • Behr J-P. The proton sponge: a trick to enter cells the viruses did not exploit. CHIMIA Int J Chem 1997; 51 (1-2): 34-6
    • (1997) CHIMIA Int J Chem , vol.51 , Issue.12 , pp. 34-36
    • Behr, J.-P.1
  • 73
    • 68549087087 scopus 로고    scopus 로고
    • Cationic nanoparticles induce nanoscale disruption in living cell plasma membranes
    • Chen J, Hessler JA, Putchakayala K, et al. Cationic nanoparticles induce nanoscale disruption in living cell plasma membranes. J Phys Chem B 2009; 113 (32): 11179-85
    • (2009) J Phys Chem B , vol.113 , Issue.32 , pp. 11179-11185
    • Chen, J.1    Hessler, J.A.2    Putchakayala, K.3
  • 74
    • 34548209237 scopus 로고    scopus 로고
    • Biodegradable nanoparticles for cytosolic delivery of therapeutics
    • Vasir JK, Labhasetwar V. Biodegradable nanoparticles for cytosolic delivery of therapeutics. Advanced Drug Deliv Rev 2007; 59 (8): 718-28
    • (2007) Advanced Drug Deliv Rev , vol.59 , Issue.8 , pp. 718-728
    • Vasir, J.K.1    Labhasetwar, V.2
  • 75
    • 77951168054 scopus 로고    scopus 로고
    • Breaking down the barriers: SiRNA delivery and endosome escape
    • Dominska M, Dykxhoorn DM. Breaking down the barriers: siRNA delivery and endosome escape. J Cell Sci 2010; 123 (Pt 8): 1183-9
    • (2010) J Cell Sci , vol.123 , pp. 1183-1189
    • Dominska, M.1    Dykxhoorn, D.M.2
  • 76
    • 14144250911 scopus 로고    scopus 로고
    • Recent advances with liposomes as pharmaceutical carriers
    • Torchilin VP. Recent advances with liposomes as pharmaceutical carriers. Nat Rev Drug Discov 2005; 4 (2): 145-60
    • (2005) Nat Rev Drug Discov , vol.4 , Issue.2 , pp. 145-160
    • Torchilin, V.P.1
  • 77
    • 0033973288 scopus 로고    scopus 로고
    • Cholesteryl hemisuccinate exhibits pH sensitive polymorphic phase behavior
    • Hafez IM, Cullis PR. Cholesteryl hemisuccinate exhibits pH sensitive polymorphic phase behavior. Biochim Biophys Acta 2000; 1463 (1): 107-14
    • (2000) Biochim Biophys Acta , vol.1463 , Issue.1 , pp. 107-114
    • Hafez, I.M.1    Cullis, P.R.2
  • 78
    • 84865849224 scopus 로고    scopus 로고
    • Phosphatase-Triggered fusogenic liposomes for cytoplasmic delivery of cell-impermeable compounds
    • Motion JP, Nguyen J, Szoka FC. Phosphatase-Triggered fusogenic liposomes for cytoplasmic delivery of cell-impermeable compounds. Angew Chem Int Ed Engl 2012; 51 (36): 9047-51
    • (2012) Angew Chem Int Ed Engl , vol.51 , Issue.36 , pp. 9047-9051
    • Motion, J.P.1    Nguyen, J.2    Szoka, F.C.3
  • 79
    • 84955189243 scopus 로고    scopus 로고
    • Plasma stable, pH-sensitive fusogenic polymer-modified liposomes: A promising carrier for mitoxantrone
    • epub ahead of print
    • Ghanbarzadeh S, Arami S, Pourmoazzen Z, et al. Plasma stable, pH-sensitive fusogenic polymer-modified liposomes: A promising carrier for mitoxantrone. J Biomaterials Applications 2013; Epub ahead of print
    • (2013) J Biomaterials Applications
    • Ghanbarzadeh, S.1    Arami, S.2    Pourmoazzen, Z.3
  • 80
    • 84873432793 scopus 로고    scopus 로고
    • A liposome-based antigen delivery system using pH-sensitive fusogenic polymers for cancer immunotherapy
    • Yuba E, Harada A, Sakanishi Y, et al. A liposome-based antigen delivery system using pH-sensitive fusogenic polymers for cancer immunotherapy. Biomaterials 2013; 34 (12): 3042-52
    • (2013) Biomaterials , vol.34 , Issue.12 , pp. 3042-3052
    • Yuba, E.1    Harada, A.2    Sakanishi, Y.3
  • 81
    • 77958063571 scopus 로고    scopus 로고
    • Rapid cytosolic delivery of luminescent nanocrystals in live cells with endosome-disrupting polymer colloids
    • Bayles AR, Chahal HS, Chahal DS, et al. Rapid cytosolic delivery of luminescent nanocrystals in live cells with endosome-disrupting polymer colloids. Nano Lett 2010; 10 (10): 4086-92
    • (2010) Nano Lett , vol.10 , Issue.10 , pp. 4086-4092
    • Bayles, A.R.1    Chahal, H.S.2    Chahal, D.S.3
  • 82
    • 84902087150 scopus 로고    scopus 로고
    • Direct cytosolic siRNA delivery by reconstituted high density lipoprotein for target-specific therapy of tumor angiogenesis
    • Ding Y, Wang Y, Zhou J, et al. Direct cytosolic siRNA delivery by reconstituted high density lipoprotein for target-specific therapy of tumor angiogenesis. Biomaterials 2014; 35 (25): 7214-27
    • (2014) Biomaterials , vol.35 , Issue.25 , pp. 7214-7227
    • Ding, Y.1    Wang, Y.2    Zhou, J.3
  • 83
    • 0033575267 scopus 로고    scopus 로고
    • Mechanism of scavenger receptor class B type I-mediated selective uptake of cholesteryl esters from high density lipoprotein to adrenal cells
    • Rodrigueza WV, Thuahnai ST, Temel RE, et al. Mechanism of scavenger receptor class B type I-mediated selective uptake of cholesteryl esters from high density lipoprotein to adrenal cells. J Biol Chem 1999; 274 (29): 20344-50
    • (1999) J Biol Chem , vol.274 , Issue.29 , pp. 20344-20350
    • Rodrigueza, W.V.1    Thuahnai, S.T.2    Temel, R.E.3
  • 84
    • 0030046797 scopus 로고    scopus 로고
    • Identification of scavenger receptor SR-BI as a high density lipoprotein receptor
    • Acton S, Rigotti A, Landschulz KT, et al. Identification of scavenger receptor SR-BI as a high density lipoprotein receptor. Science 1996; 271 (5248): 518-20
    • (1996) Science , vol.271 , Issue.5248 , pp. 518-520
    • Acton, S.1    Rigotti, A.2    Landschulz, K.T.3
  • 85
    • 84902147940 scopus 로고    scopus 로고
    • Imaging the cytosolic drug delivery mechanism of hdl-like nanoparticles
    • Lin Q, Chen J, Ng KK, et al. Imaging the Cytosolic Drug Delivery Mechanism of HDL-Like Nanoparticles. Pharm Res 2014; 31 (6): 1438-49
    • (2014) Pharm Res , vol.31 , Issue.6 , pp. 1438-1449
    • Lin, Q.1    Chen, J.2    Ng, K.K.3
  • 86
    • 84884131045 scopus 로고    scopus 로고
    • Cytoplasm-responsive nanocarriers conjugated with a functional cell-penetrating peptide for systemic siRNA delivery
    • Tanaka K, Kanazawa T, Horiuchi S, et al. Cytoplasm-responsive nanocarriers conjugated with a functional cell-penetrating peptide for systemic siRNA delivery. Int J Pharm 2013; 455 (1-2): 40-7
    • (2013) Int J Pharm , vol.455 , Issue.12 , pp. 40-47
    • Tanaka, K.1    Kanazawa, T.2    Horiuchi, S.3
  • 87
    • 84896708224 scopus 로고    scopus 로고
    • Matrix metalloproteinase 2-sensitive multifunctional polymeric micelles for tumor-specific co-delivery of siRNA and hydrophobic drugs
    • Zhu L, Perche F, Wang T, et al. Matrix metalloproteinase 2-sensitive multifunctional polymeric micelles for tumor-specific co-delivery of siRNA and hydrophobic drugs. Biomaterials 2014; 35 (13): 4213-22
    • (2014) Biomaterials , vol.35 , Issue.13 , pp. 4213-4222
    • Zhu, L.1    Perche, F.2    Wang, T.3
  • 88
    • 0030994111 scopus 로고    scopus 로고
    • A gene delivery system activatable by disease-Associated matrix metalloproteinases
    • Peng KW, Morling FJ, Cosset FL, et al. A gene delivery system activatable by disease-Associated matrix metalloproteinases. Hum Gene Ther 1997; 8 (6): 729-38
    • (1997) Hum Gene Ther , vol.8 , Issue.6 , pp. 729-738
    • Peng, K.W.1    Morling, F.J.2    Cosset, F.L.3
  • 89
    • 13844275977 scopus 로고    scopus 로고
    • Nuclear delivery of macromolecules: Barriers and carriers
    • Belting M, Sandgren S, Wittrup A. Nuclear delivery of macromolecules: barriers and carriers. Advanced Drug Deliv Rev 2005; 57 (4): 505-27
    • (2005) Advanced Drug Deliv Rev , vol.57 , Issue.4 , pp. 505-527
    • Belting, M.1    Sandgren, S.2    Wittrup, A.3
  • 90
    • 80054108776 scopus 로고    scopus 로고
    • Nuclear drug delivery for cancer chemotherapy
    • Sui M, Liu W, Shen Y. Nuclear drug delivery for cancer chemotherapy. J Controlled Release 2011; 155 (2): 227-36
    • (2011) J Controlled Release , vol.155 , Issue.2 , pp. 227-236
    • Sui, M.1    Liu, W.2    Shen, Y.3
  • 91
    • 0034717044 scopus 로고    scopus 로고
    • Gatekeepers of the nucleus
    • Wente SR. Gatekeepers of the nucleus. Science 2000; 288 (5470): 1374-7
    • (2000) Science , vol.288 , Issue.5470 , pp. 1374-1377
    • Wente, S.R.1
  • 92
    • 0033279841 scopus 로고    scopus 로고
    • Transport between the cell nucleus and the cytoplasm
    • Gorlich D, Kutay U. Transport between the cell nucleus and the cytoplasm. Ann Rev Cell Develop Biol 1999; 15: 607-60
    • (1999) Ann Rev Cell Develop Biol , vol.15 , pp. 607-660
    • Gorlich, D.1    Kutay, U.2
  • 93
    • 0039115156 scopus 로고    scopus 로고
    • Transport into and out of the cell nucleus
    • Gorlich D. Transport into and out of the cell nucleus. EMBO J 1998; 17 (10): 2721-7
    • (1998) EMBO J , vol.17 , Issue.10 , pp. 2721-2727
    • Gorlich, D.1
  • 94
    • 0021716406 scopus 로고
    • A short amino acid sequence able to specify nuclear location
    • Kalderon D, Roberts BL, Richardson WD, et al. A short amino acid sequence able to specify nuclear location. Cell 1984; 39 (3 Pt 2): 499-509
    • (1984) Cell , vol.39 , Issue.3 , pp. 499-509
    • Kalderon, D.1    Roberts, B.L.2    Richardson, W.D.3
  • 95
    • 84856904042 scopus 로고    scopus 로고
    • Block copolymer micelles target Auger electron radiotherapy to the nucleus of HER2-positive breast cancer cells
    • Hoang B, Reilly RM, Allen C. Block copolymer micelles target Auger electron radiotherapy to the nucleus of HER2-positive breast cancer cells. Biomacromolecules 2012; 13 (2): 455-65
    • (2012) Biomacromolecules , vol.13 , Issue.2 , pp. 455-465
    • Hoang, B.1    Reilly, R.M.2    Allen, C.3
  • 96
    • 84860355186 scopus 로고    scopus 로고
    • Direct observation of nanoparticle-cancer cell nucleus interactions
    • Dam DH, Lee JH, Sisco PN, et al. Direct observation of nanoparticle-cancer cell nucleus interactions. ACS Nano 2012; 6 (4): 3318-26
    • (2012) ACS Nano , vol.6 , Issue.4 , pp. 3318-3326
    • Dam, D.H.1    Lee, J.H.2    Sisco, P.N.3
  • 97
    • 84887940690 scopus 로고    scopus 로고
    • Drug-loading capacity and nuclear targeting of multiwalled carbon nanotubes grafted with anionic amphiphilic copolymers
    • Tsai HC, Lin JY, Maryani F, et al. Drug-loading capacity and nuclear targeting of multiwalled carbon nanotubes grafted with anionic amphiphilic copolymers. Int J Nanomed 2013; 8: 4427-40
    • (2013) Int J Nanomed , vol.8 , pp. 4427-4440
    • Tsai, H.C.1    Lin, J.Y.2    Maryani, F.3
  • 98
    • 11144331073 scopus 로고    scopus 로고
    • Steroids dilate nuclear pores imaged with atomic force microscopy
    • Shahin V, Albermann L, Schillers H, et al. Steroids dilate nuclear pores imaged with atomic force microscopy. J Cell Physiol 2005; 202 (2): 591-601
    • (2005) J Cell Physiol , vol.202 , Issue.2 , pp. 591-601
    • Shahin, V.1    Albermann, L.2    Schillers, H.3
  • 99
    • 84870342369 scopus 로고    scopus 로고
    • Transferrin-PEG-PE modified dexamethasone conjugated cationic lipid carrier mediated gene delivery system for tumor-Targeted transfection
    • Wang W, Zhou F, Ge L, et al. Transferrin-PEG-PE modified dexamethasone conjugated cationic lipid carrier mediated gene delivery system for tumor-Targeted transfection. Int J Nanomed 2012; 7: 2513-22
    • (2012) Int J Nanomed , vol.7 , pp. 2513-2522
    • Wang, W.1    Zhou, F.2    Ge, L.3
  • 101
    • 24044464534 scopus 로고    scopus 로고
    • Mitochondria and reactive oxygen species: An evolution in function
    • Gutterman DD. Mitochondria and reactive oxygen species: an evolution in function. Circulation Res 2005; 97 (4): 302-4
    • (2005) Circulation Res , vol.97 , Issue.4 , pp. 302-304
    • Gutterman, D.D.1
  • 102
    • 0032575752 scopus 로고    scopus 로고
    • Mitochondria and apoptosis
    • Green DR, Reed JC. Mitochondria and apoptosis. Science 1998; 281 (5381): 1309-12
    • (1998) Science , vol.281 , Issue.5381 , pp. 1309-1312
    • Green, D.R.1    Reed, J.C.2
  • 103
    • 0036140053 scopus 로고    scopus 로고
    • Mitochondrial calcium homeostasis: Mechanisms and molecules
    • Vandecasteele G, Szabadkai G, Rizzuto R. Mitochondrial calcium homeostasis: mechanisms and molecules. IUBMB Life 2001; 52 (3-5): 213-19
    • (2001) IUBMB Life , vol.52 , Issue.35 , pp. 213-219
    • Vandecasteele, G.1    Szabadkai, G.2    Rizzuto, R.3
  • 104
    • 34249671789 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and molecular pathways of disease
    • Pieczenik SR, Neustadt J. Mitochondrial dysfunction and molecular pathways of disease. Exp Mol Pathol 2007; 83 (1): 84-92
    • (2007) Exp Mol Pathol , vol.83 , Issue.1 , pp. 84-92
    • Pieczenik, S.R.1    Neustadt, J.2
  • 105
    • 33746891176 scopus 로고    scopus 로고
    • Mitochondrial DNA mutations in human cancer
    • Chatterjee A, Mambo E, Sidransky D. Mitochondrial DNA mutations in human cancer. Oncogene 2006; 25 (34): 4663-74
    • (2006) Oncogene , vol.25 , Issue.34 , pp. 4663-4674
    • Chatterjee, A.1    Mambo, E.2    Sidransky, D.3
  • 106
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011; 144 (5): 646-74
    • (2011) Cell , vol.144 , Issue.5 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 107
    • 79955591914 scopus 로고    scopus 로고
    • Recent advances in apoptosis, mitochondria and drug resistance in cancer cells
    • Indran IR, Tufo G, Pervaiz S, et al. Recent advances in apoptosis, mitochondria and drug resistance in cancer cells. Biochim Biophys Acta 2011; 1807 (6): 735-45
    • (2011) Biochim Biophys Acta , vol.1807 , Issue.6 , pp. 735-745
    • Indran, I.R.1    Tufo, G.2    Pervaiz, S.3
  • 108
    • 41149105722 scopus 로고    scopus 로고
    • Mitochondria in cancer cells: What is so special about them?
    • Gogvadze V, Orrenius S, Zhivotovsky B. Mitochondria in cancer cells: what is so special about them? Trends Cell Biol 2008; 18 (4): 165-73
    • (2008) Trends Cell Biol , vol.18 , Issue.4 , pp. 165-173
    • Gogvadze, V.1    Orrenius, S.2    Zhivotovsky, B.3
  • 109
    • 14344250256 scopus 로고    scopus 로고
    • Imbalance of the mitochondrial pro-And anti-Apoptotic mediators in neuroblastoma tumours with unfavourable biology
    • Abel F, Sjoberg RM, Nilsson S, et al. Imbalance of the mitochondrial pro-And anti-Apoptotic mediators in neuroblastoma tumours with unfavourable biology. Eur J Cancer 2005; 41 (4): 635-46
    • (2005) Eur J Cancer , vol.41 , Issue.4 , pp. 635-646
    • Abel, F.1    Sjoberg, R.M.2    Nilsson, S.3
  • 110
    • 84896719524 scopus 로고    scopus 로고
    • Nanopreparations for organelle-specific delivery in cancer
    • Biswas S, Torchilin VP. Nanopreparations for organelle-specific delivery in cancer. Advanced Drug Deliv Rev 2014; 66: 26-41
    • (2014) Advanced Drug Deliv Rev , vol.66 , pp. 26-41
    • Biswas, S.1    Torchilin, V.P.2
  • 111
    • 77953131908 scopus 로고    scopus 로고
    • Targeting mitochondria for cancer therapy
    • Fulda S, Galluzzi L, Kroemer G. Targeting mitochondria for cancer therapy. Nat Rev Drug Discov 2010; 9 (6): 447-64
    • (2010) Nat Rev Drug Discov , vol.9 , Issue.6 , pp. 447-464
    • Fulda, S.1    Galluzzi, L.2    Kroemer, G.3
  • 112
    • 84867089289 scopus 로고    scopus 로고
    • Engineering of blended nanoparticle platform for delivery of mitochondria-Acting therapeutics
    • Marrache S, Dhar S. Engineering of blended nanoparticle platform for delivery of mitochondria-Acting therapeutics. Proc Natl Acad Sci USA 2012; 109 (40): 16288-93
    • (2012) Proc Natl Acad Sci USA , vol.109 , Issue.40 , pp. 16288-16293
    • Marrache, S.1    Dhar, S.2
  • 113
    • 0030064081 scopus 로고    scopus 로고
    • MKT-077, a novel rhodacyanine dye in clinical trials, exhibits anticarcinoma activity in preclinical studies based on selective mitochondrial accumulation
    • Koya K, Li Y, Wang H, et al. MKT-077, a novel rhodacyanine dye in clinical trials, exhibits anticarcinoma activity in preclinical studies based on selective mitochondrial accumulation. Cancer Res 1996; 56 (3): 538-43
    • (1996) Cancer Res , vol.56 , Issue.3 , pp. 538-543
    • Koya, K.1    Li, Y.2    Wang, H.3
  • 114
    • 70350462567 scopus 로고    scopus 로고
    • Potential use of cetrimonium bromide as an apoptosis-promoting anticancer agent for head and neck cancer
    • Ito E, Yip KW, Katz D, et al. Potential use of cetrimonium bromide as an apoptosis-promoting anticancer agent for head and neck cancer. Mol Pharmacol 2009; 76 (5): 969-83
    • (2009) Mol Pharmacol , vol.76 , Issue.5 , pp. 969-983
    • Ito, E.1    Yip, K.W.2    Katz, D.3
  • 116
    • 34147167044 scopus 로고    scopus 로고
    • Imaging of mitochondrial polarization and depolarization with cationic fluorophores
    • In: Liza AP, Eric AS, editors. Elsevier/Academic Press, Amsterdam; Boston
    • Lemasters JJ, Ramshesh VK. Imaging of Mitochondrial Polarization and Depolarization with Cationic Fluorophores. In: Liza AP, Eric AS.,. editors. Methods in cell biology. Elsevier/Academic Press, Amsterdam; Boston; 2007. p. 283-95
    • (2007) Methods in Cell Biology , pp. 283-295
    • Lemasters, J.J.1    Ramshesh, V.K.2
  • 117
    • 0031916033 scopus 로고    scopus 로고
    • DQAsomes: A novel potential drug and gene delivery system made from Dequalinium
    • Weissig V, Lasch J, Erdos G, et al. DQAsomes: a novel potential drug and gene delivery system made from Dequalinium. Pharm Res 1998; 15 (2): 334-7
    • (1998) Pharm Res , vol.15 , Issue.2 , pp. 334-337
    • Weissig, V.1    Lasch, J.2    Erdos, G.3
  • 118
    • 26444444018 scopus 로고    scopus 로고
    • Mitochondrial leader sequence-Plasmid DNA conjugates delivered into mammalian cells by DQAsomes co-localize with mitochondria
    • D'Souza GG, Boddapati SV, Weissig V. Mitochondrial leader sequence-plasmid DNA conjugates delivered into mammalian cells by DQAsomes co-localize with mitochondria. Mitochondrion 2005; 5 (5): 352-8
    • (2005) Mitochondrion , vol.5 , Issue.5 , pp. 352-358
    • D'Souza, G.G.1    Boddapati, S.V.2    Weissig, V.3
  • 119
    • 49149124239 scopus 로고    scopus 로고
    • Nanocarrier-Assisted sub-cellular targeting to the site of mitochondria improves the pro-Apoptotic activity of paclitaxel
    • D'Souza GG, Cheng SM, Boddapati SV, et al. Nanocarrier-Assisted sub-cellular targeting to the site of mitochondria improves the pro-Apoptotic activity of paclitaxel. J Drug Target 2008; 16 (7): 578-85
    • (2008) J Drug Target , vol.16 , Issue.7 , pp. 578-585
    • D'Souza, G.G.1    Cheng, S.M.2    Boddapati, S.V.3
  • 120
    • 0141763942 scopus 로고    scopus 로고
    • DQAsome-mediated delivery of plasmid DNA toward mitochondria in living cells
    • D'Souza GG, Rammohan R, Cheng SM, et al. DQAsome-mediated delivery of plasmid DNA toward mitochondria in living cells. J Controlled Release 2003; 92 (1-2): 189-97
    • (2003) J Controlled Release , vol.92 , Issue.12 , pp. 189-197
    • D'Souza, G.G.1    Rammohan, R.2    Cheng, S.M.3
  • 121
    • 38349036163 scopus 로고    scopus 로고
    • MITO-Porter: A liposome-based carrier system for delivery of macromolecules into mitochondria via membrane fusion
    • Yamada Y, Akita H, Kamiya H, et al. MITO-Porter: A liposome-based carrier system for delivery of macromolecules into mitochondria via membrane fusion. Biochim Biophys Acta 2008; 1778 (2): 423-32
    • (2008) Biochim Biophys Acta , vol.1778 , Issue.2 , pp. 423-432
    • Yamada, Y.1    Akita, H.2    Kamiya, H.3
  • 122
    • 83555164614 scopus 로고    scopus 로고
    • Delivery of bioactive molecules to the mitochondrial genome using a membrane-fusing, liposome-based carrier, DF-MITO-Porter
    • Yamada Y, Harashima H. Delivery of bioactive molecules to the mitochondrial genome using a membrane-fusing, liposome-based carrier, DF-MITO-Porter. Biomaterials 2012; 33 (5): 1589-95
    • (2012) Biomaterials , vol.33 , Issue.5 , pp. 1589-1595
    • Yamada, Y.1    Harashima, H.2
  • 123
    • 79961023252 scopus 로고    scopus 로고
    • Dual function MITO-Porter, a nano carrier integrating both efficient cytoplasmic delivery and mitochondrial macromolecule delivery
    • Yamada Y, Furukawa R, Yasuzaki Y, et al. Dual function MITO-Porter, a nano carrier integrating both efficient cytoplasmic delivery and mitochondrial macromolecule delivery. Mol Ther 2011; 19 (8): 1449-56
    • (2011) Mol Ther , vol.19 , Issue.8 , pp. 1449-1456
    • Yamada, Y.1    Furukawa, R.2    Yasuzaki, Y.3
  • 124
    • 4544370680 scopus 로고    scopus 로고
    • Cell-permeable peptide antioxidants targeted to inner mitochondrial membrane inhibit mitochondrial swelling, oxidative cell death, and reperfusion injury
    • Zhao K, Zhao GM, Wu D, et al. Cell-permeable peptide antioxidants targeted to inner mitochondrial membrane inhibit mitochondrial swelling, oxidative cell death, and reperfusion injury. J Biol Chem 2004; 279 (33): 34682-90
    • (2004) J Biol Chem , vol.279 , Issue.33 , pp. 34682-34690
    • Zhao, K.1    Zhao, G.M.2    Wu, D.3
  • 125
    • 33646369165 scopus 로고    scopus 로고
    • Cell-permeable, mitochondrial-Targeted, peptide antioxidants
    • Szeto HH. Cell-permeable, mitochondrial-Targeted, peptide antioxidants. AAPS J 2006; 8 (2): E277-83
    • (2006) AAPS J , vol.8 , Issue.2 , pp. E277-E283
    • Szeto, H.H.1
  • 126
    • 41949083981 scopus 로고    scopus 로고
    • Mitochondria-penetrating peptides
    • Horton KL, Stewart KM, Fonseca SB, et al. Mitochondria-penetrating peptides. Chem Biol 2008; 15 (4): 375-82
    • (2008) Chem Biol , vol.15 , Issue.4 , pp. 375-382
    • Horton, K.L.1    Stewart, K.M.2    Fonseca, S.B.3
  • 127
    • 79955385201 scopus 로고    scopus 로고
    • Rerouting chlorambucil to mitochondria combats drug deactivation and resistance in cancer cells
    • Fonseca SB, Pereira MP, Mourtada R, et al. Rerouting chlorambucil to mitochondria combats drug deactivation and resistance in cancer cells. Chem Biol 2011; 18 (4): 445-53
    • (2011) Chem Biol , vol.18 , Issue.4 , pp. 445-453
    • Fonseca, S.B.1    Pereira, M.P.2    Mourtada, R.3
  • 128
    • 0035344460 scopus 로고    scopus 로고
    • Versatility of the mitochondrial protein import machinery
    • Pfanner N, Geissler A. Versatility of the mitochondrial protein import machinery. Nat Rev Mol Biol 2001; 2 (5): 339-49
    • (2001) Nat Rev Mol Biol , vol.2 , Issue.5 , pp. 339-349
    • Pfanner, N.1    Geissler, A.2
  • 129
    • 84921534709 scopus 로고    scopus 로고
    • Dual peptide conjugation strategy for improved cellular uptake and mitochondria targeting
    • Lin R, Zhang P, Cheetham AG, et al. Dual peptide conjugation strategy for improved cellular uptake and mitochondria targeting. Bioconjugate Chem 2015; 26 (1): 71-7
    • (2015) Bioconjugate Chem , vol.26 , Issue.1 , pp. 71-77
    • Lin, R.1    Zhang, P.2    Cheetham, A.G.3
  • 130
    • 84882827086 scopus 로고    scopus 로고
    • Enhancement in selective mitochondrial association by direct modification of a mitochondrial targeting signal peptide on a liposomal based nanocarrier
    • Yamada Y, Harashima H. Enhancement in selective mitochondrial association by direct modification of a mitochondrial targeting signal peptide on a liposomal based nanocarrier. Mitochondrion 2013; 13 (5): 526-32
    • (2013) Mitochondrion , vol.13 , Issue.5 , pp. 526-532
    • Yamada, Y.1    Harashima, H.2
  • 131
    • 84881565288 scopus 로고    scopus 로고
    • The lysosome: From waste bag to potential therapeutic target
    • Appelqvist H, Waster P, Kagedal K, et al. The lysosome: from waste bag to potential therapeutic target. J Mol Cell Biol 2013; 5 (4): 214-26
    • (2013) J Mol Cell Biol , vol.5 , Issue.4 , pp. 214-226
    • Appelqvist, H.1    Waster, P.2    Kagedal, K.3
  • 132
    • 84861671713 scopus 로고    scopus 로고
    • Lysosomal pathways to cell death and their therapeutic applications
    • Cesen MH, Pegan K, Spes A, et al. Lysosomal pathways to cell death and their therapeutic applications. Experimental Cell Res 2012; 318 (11): 1245-51
    • (2012) Experimental Cell Res , vol.318 , Issue.11 , pp. 1245-1251
    • Cesen, M.H.1    Pegan, K.2    Spes, A.3
  • 133
    • 62949128915 scopus 로고    scopus 로고
    • Lysosomal involvement in cell death and cancer
    • Kirkegaard T, Jaattela M. Lysosomal involvement in cell death and cancer. Biochim Biophys Acta 2009; 1793 (4): 746-54
    • (2009) Biochim Biophys Acta , vol.1793 , Issue.4 , pp. 746-754
    • Kirkegaard, T.1    Jaattela, M.2
  • 134
    • 84892963544 scopus 로고    scopus 로고
    • Cancer therapy: Targeting mitochondria and other sub-cellular organelles
    • Ubah OC, Wallace HM. Cancer therapy: Targeting mitochondria and other sub-cellular organelles. Current Pharm Des 2014; 20 (2): 201-22
    • (2014) Current Pharm des , vol.20 , Issue.2 , pp. 201-222
    • Ubah, O.C.1    Wallace, H.M.2
  • 135
    • 28544435485 scopus 로고    scopus 로고
    • Lysosomes and autophagy in cell death control
    • Kroemer G, Jaattela M. Lysosomes and autophagy in cell death control. Nat Rev Cancer 2005; 5 (11): 886-97
    • (2005) Nat Rev Cancer , vol.5 , Issue.11 , pp. 886-897
    • Kroemer, G.1    Jaattela, M.2
  • 136
    • 84903709001 scopus 로고    scopus 로고
    • Targeting lysosomal membrane permeabilization to induce and image apoptosis in cancer cells by multifunctional Au-ZnO hybrid nanoparticles
    • Gao W, Cao W, Zhang H, et al. Targeting lysosomal membrane permeabilization to induce and image apoptosis in cancer cells by multifunctional Au-ZnO hybrid nanoparticles. Chem Commun (Camb) 2014; 50 (60): 8117-20
    • (2014) Chem Commun (Camb) , vol.50 , Issue.60 , pp. 8117-8120
    • Gao, W.1    Cao, W.2    Zhang, H.3
  • 137
    • 84856384153 scopus 로고    scopus 로고
    • Increased apoptosis in cancer cells in vitro and in vivo by ceramides in transferrin-modified liposomes
    • Koshkaryev A, Piroyan A, Torchilin VP. Increased apoptosis in cancer cells in vitro and in vivo by ceramides in transferrin-modified liposomes. Cancer Biol Ther 2012; 13 (1): 50-60
    • (2012) Cancer Biol Ther , vol.13 , Issue.1 , pp. 50-60
    • Koshkaryev, A.1    Piroyan, A.2    Torchilin, V.P.3
  • 138
    • 17144361820 scopus 로고    scopus 로고
    • Lysosomes as Targets for Cancer Therapy
    • Fehrenbacher N, Jäättelä M. Lysosomes as Targets for Cancer Therapy. Cancer Res 2005 2005; 65 (8): 2993-95
    • (2005) Cancer Res 2005 , vol.65 , Issue.8 , pp. 2993-2995
    • Fehrenbacher, N.1    Jäättelä, M.2
  • 139
    • 84905757850 scopus 로고    scopus 로고
    • A lysosome-Targeted drug delivery system based on sorbitol backbone towards efficient cancer therapy
    • Maniganda S, Sankar V, Nair JB, et al. A lysosome-Targeted drug delivery system based on sorbitol backbone towards efficient cancer therapy. Organic Biomol Chem 2014; 12 (34): 6564-9
    • (2014) Organic Biomol Chem , vol.12 , Issue.34 , pp. 6564-6569
    • Maniganda, S.1    Sankar, V.2    Nair, J.B.3
  • 140
    • 4344651318 scopus 로고    scopus 로고
    • Heat shock protein 70 promotes cell survival by inhibiting lysosomal membrane permeabilization
    • Nylandsted J, Gyrd-Hansen M, Danielewicz A, et al. Heat shock protein 70 promotes cell survival by inhibiting lysosomal membrane permeabilization. J Exp Med 2004; 200 (4): 425-35
    • (2004) J Exp Med , vol.200 , Issue.4 , pp. 425-435
    • Nylandsted, J.1    Gyrd-Hansen, M.2    Danielewicz, A.3
  • 141
    • 0034608892 scopus 로고    scopus 로고
    • Selective depletion of heat shock protein 70 (Hsp70) activates a tumor-specific death program that is independent of caspases and bypasses Bcl-2
    • Nylandsted J, Rohde M, Brand K, et al. Selective depletion of heat shock protein 70 (Hsp70) activates a tumor-specific death program that is independent of caspases and bypasses Bcl-2. Proc Natl Acad Sci USA 2000; 97 (14): 7871-6
    • (2000) Proc Natl Acad Sci USA , vol.97 , Issue.14 , pp. 7871-7876
    • Nylandsted, J.1    Rohde, M.2    Brand, K.3
  • 142
    • 84885050263 scopus 로고    scopus 로고
    • Hsp70 silencing with siRNA in nanocarriers enhances cancer cell death induced by the inhibitor of Hsp90
    • Matokanovic M, Barisic K, Filipovic-Grcic J, et al. Hsp70 silencing with siRNA in nanocarriers enhances cancer cell death induced by the inhibitor of Hsp90. Eur J Pharm Sci 2013; 50 (1): 149-58
    • (2013) Eur J Pharm Sci , vol.50 , Issue.1 , pp. 149-158
    • Matokanovic, M.1    Barisic, K.2    Filipovic-Grcic, J.3
  • 143
    • 84896759012 scopus 로고    scopus 로고
    • PEGylated liposomes with NGR ligand and heat-Activable cell-penetrating peptide-doxorubicin conjugate for tumor-specific therapy
    • Yang Y, Xie X, Cai X, et al. PEGylated liposomes with NGR ligand and heat-Activable cell-penetrating peptide-doxorubicin conjugate for tumor-specific therapy. Biomaterials 2014; 35 (14): 4368-81
    • (2014) Biomaterials , vol.35 , Issue.14 , pp. 4368-4381
    • Yang, Y.1    Xie, X.2    Cai, X.3
  • 144
    • 84894556749 scopus 로고    scopus 로고
    • Cell-penetrating peptide-conjugated lipid nanoparticles for siRNA delivery
    • Asai T, Tsuzuku T, Takahashi S, et al. Cell-penetrating peptide-conjugated lipid nanoparticles for siRNA delivery. Biochem Biophys Res Commun 2014; 444 (4): 599-604
    • (2014) Biochem Biophys Res Commun , vol.444 , Issue.4 , pp. 599-604
    • Asai, T.1    Tsuzuku, T.2    Takahashi, S.3
  • 145
    • 84924964682 scopus 로고    scopus 로고
    • Dual-modified liposomes with a two-photon-sensitive cell penetrating peptide and NGR ligand for siRNA targeting delivery
    • Yang Y, Xie X, Wang Z, et al. Dual-modified liposomes with a two-photon-sensitive cell penetrating peptide and NGR ligand for siRNA targeting delivery. Biomaterials 2015; 48: 84-96
    • (2015) Biomaterials , vol.48 , pp. 84-96
    • Yang, Y.1    Xie, X.2    Wang, Z.3
  • 146
    • 84921949683 scopus 로고    scopus 로고
    • Conjugation of cell-penetrating peptides with poly(lactic-co-glycolic acid)-polyethylene glycol nanoparticles improves ocular drug delivery
    • Vasconcelos A, Vega E, Perez Y, et al. Conjugation of cell-penetrating peptides with poly(lactic-co-glycolic acid)-polyethylene glycol nanoparticles improves ocular drug delivery. Int J Nanomed 2015; 10: 609-31
    • (2015) Int J Nanomed , vol.10 , pp. 609-631
    • Vasconcelos, A.1    Vega, E.2    Perez, Y.3
  • 147
    • 84923376183 scopus 로고    scopus 로고
    • Synthesis and characterization of an octaarginine functionalized graphene oxide nano-carrier for gene delivery applications
    • Imani R, Emami SH, Faghihi S. Synthesis and characterization of an octaarginine functionalized graphene oxide nano-carrier for gene delivery applications. Phys Chem Chem Phys 2015; 17 (9): 6328-39
    • (2015) Phys Chem Chem Phys , vol.17 , Issue.9 , pp. 6328-6339
    • Imani, R.1    Emami, S.H.2    Faghihi, S.3
  • 148
    • 84923197343 scopus 로고    scopus 로고
    • Enzyme responsive mesoporous silica nanoparticles for targeted tumor therapy in vitro and in vivo
    • Liu J, Zhang B, Luo Z, et al. Enzyme responsive mesoporous silica nanoparticles for targeted tumor therapy in vitro and in vivo. Nanoscale 2015; 7 (8): 3614-26
    • (2015) Nanoscale , vol.7 , Issue.8 , pp. 3614-3626
    • Liu, J.1    Zhang, B.2    Luo, Z.3
  • 149
    • 84902551145 scopus 로고    scopus 로고
    • Matrix metalloproteinase 2-responsive micelle for siRNA delivery
    • Wang HX, Yang XZ, Sun CY, et al. Matrix metalloproteinase 2-responsive micelle for siRNA delivery. Biomaterials 2014; 35 (26): 7622-34
    • (2014) Biomaterials , vol.35 , Issue.26 , pp. 7622-7634
    • Wang, H.X.1    Yang, X.Z.2    Sun, C.Y.3
  • 150
    • 84877040295 scopus 로고    scopus 로고
    • Tumor targeting and microenvironment-responsive nanoparticles for gene delivery
    • Huang S, Shao K, Kuang Y, et al. Tumor targeting and microenvironment-responsive nanoparticles for gene delivery. Biomaterials 2013; 34 (21): 5294-302
    • (2013) Biomaterials , vol.34 , Issue.21 , pp. 5294-5302
    • Huang, S.1    Shao, K.2    Kuang, Y.3
  • 151
    • 84858718533 scopus 로고    scopus 로고
    • Dual peptide nucleic acid-And peptide-functionalized shell crosslinked nanoparticles designed to target mRNA toward the diagnosis and treatment of acute lung injury
    • Shrestha R, Shen Y, Pollack KA, et al. Dual peptide nucleic acid-And peptide-functionalized shell crosslinked nanoparticles designed to target mRNA toward the diagnosis and treatment of acute lung injury. Bioconjugate Chem 2012; 23 (3): 574-85
    • (2012) Bioconjugate Chem , vol.23 , Issue.3 , pp. 574-585
    • Shrestha, R.1    Shen, Y.2    Pollack, K.A.3
  • 152
    • 84906087666 scopus 로고    scopus 로고
    • Enzyme-responsive cell-penetrating peptide conjugated mesoporous silica quantum dot nanocarriers for controlled release of nucleus-Targeted drug molecules and real-Time intracellular fluorescence imaging of tumor cells
    • Li J, Liu F, Shao Q, et al. Enzyme-responsive cell-penetrating peptide conjugated mesoporous silica quantum dot nanocarriers for controlled release of nucleus-Targeted drug molecules and real-Time intracellular fluorescence imaging of tumor cells. Advanced healthcare materials 2014; 3 (8): 1230-9
    • (2014) Advanced Healthcare Materials , vol.3 , Issue.8 , pp. 1230-1239
    • Li, J.1    Liu, F.2    Shao, Q.3
  • 153
    • 84878230631 scopus 로고    scopus 로고
    • Bleomycin in octaarginine-modified fusogenic liposomes results in improved tumor growth inhibition
    • Koshkaryev A, Piroyan A, Torchilin VP. Bleomycin in octaarginine-modified fusogenic liposomes results in improved tumor growth inhibition. Cancer Lett 2013; 334 (2): 293-301
    • (2013) Cancer Lett , vol.334 , Issue.2 , pp. 293-301
    • Koshkaryev, A.1    Piroyan, A.2    Torchilin, V.P.3
  • 154
    • 84870354356 scopus 로고    scopus 로고
    • PH-sensitive poly(histidine)-PEG/DSPE-PEG co-polymer micelles for cytosolic drug delivery
    • Wu H, Zhu L, Torchilin VP. pH-sensitive poly(histidine)-PEG/DSPE-PEG co-polymer micelles for cytosolic drug delivery. Biomaterials 2013; 34 (4): 1213-22
    • (2013) Biomaterials , vol.34 , Issue.4 , pp. 1213-1222
    • Wu, H.1    Zhu, L.2    Torchilin, V.P.3
  • 155
    • 77955236446 scopus 로고    scopus 로고
    • Cytoplasmic delivery of liposomes into MCF-7 breast cancer cells mediated by cell-specific phage fusion coat protein
    • Wang T, Yang S, Petrenko VA, et al. Cytoplasmic delivery of liposomes into MCF-7 breast cancer cells mediated by cell-specific phage fusion coat protein. Mol Pharm 2010; 7 (4): 1149-58
    • (2010) Mol Pharm , vol.7 , Issue.4 , pp. 1149-1158
    • Wang, T.1    Yang, S.2    Petrenko, V.A.3
  • 156
    • 84865593616 scopus 로고    scopus 로고
    • Smart multilayered assembly for biocompatible siRNA delivery featuring dissolvable silica, endosome-disrupting polycation, and detachable PEG
    • Suma T, Miyata K, Anraku Y, et al. Smart multilayered assembly for biocompatible siRNA delivery featuring dissolvable silica, endosome-disrupting polycation, and detachable PEG. ACS Nano 2012; 6 (8): 6693-705
    • (2012) ACS Nano , vol.6 , Issue.8 , pp. 6693-6705
    • Suma, T.1    Miyata, K.2    Anraku, Y.3
  • 157
    • 84860662855 scopus 로고    scopus 로고
    • Liposomes loaded with paclitaxel and modified with novel triphenylphosphonium-PEG-PE conjugate possess low toxicity, target mitochondria and demonstrate enhanced antitumor effects in vitro and in vivo
    • Biswas S, Dodwadkar NS, Deshpande PP, et al. Liposomes loaded with paclitaxel and modified with novel triphenylphosphonium-PEG-PE conjugate possess low toxicity, target mitochondria and demonstrate enhanced antitumor effects in vitro and in vivo. J Controlled Release 2012; 159 (3): 393-402
    • (2012) J Controlled Release , vol.159 , Issue.3 , pp. 393-402
    • Biswas, S.1    Dodwadkar, N.S.2    Deshpande, P.P.3
  • 158
    • 84859827353 scopus 로고    scopus 로고
    • Surface conjugation of triphenylphosphonium to target poly(amidoamine) dendrimers to mitochondria
    • Biswas S, Dodwadkar NS, Piroyan A, et al. Surface conjugation of triphenylphosphonium to target poly(amidoamine) dendrimers to mitochondria. Biomaterials 2012; 33 (18): 4773-82
    • (2012) Biomaterials , vol.33 , Issue.18 , pp. 4773-4782
    • Biswas, S.1    Dodwadkar, N.S.2    Piroyan, A.3
  • 159
    • 84890852662 scopus 로고    scopus 로고
    • Targeted surface-functionalized gold nanoclusters for mitochondrial imaging
    • Zhuang Q, Jia H, Du L, et al. Targeted surface-functionalized gold nanoclusters for mitochondrial imaging. Biosensors Bioelectron 2014; 55: 76-82
    • (2014) Biosensors Bioelectron , vol.55 , pp. 76-82
    • Zhuang, Q.1    Jia, H.2    Du, L.3
  • 160
    • 84902972220 scopus 로고    scopus 로고
    • Rhodamine based plasmid DNA nanoparticles for mitochondrial gene therapy
    • Santos J, Sousa F, Queiroz J, et al. Rhodamine based plasmid DNA nanoparticles for mitochondrial gene therapy. Colloids and surfaces B, Biointerfaces 2014; 121: 129-40
    • (2014) Colloids and Surfaces B, Biointerfaces , vol.121 , pp. 129-140
    • Santos, J.1    Sousa, F.2    Queiroz, J.3
  • 161
    • 84856224083 scopus 로고    scopus 로고
    • Expression of GFP in the mitochondrial compartment using DQAsome-mediated delivery of an artificial mini-mitochondrial genome
    • Lyrawati D, Trounson A, Cram D. Expression of GFP in the mitochondrial compartment using DQAsome-mediated delivery of an artificial mini-mitochondrial genome. Pharm Res 2011; 28 (11): 2848-62
    • (2011) Pharm Res , vol.28 , Issue.11 , pp. 2848-2862
    • Lyrawati, D.1    Trounson, A.2    Cram, D.3
  • 162
    • 80051718862 scopus 로고    scopus 로고
    • Targeting of lysosomes by liposomes modified with octadecyl-rhodamine B
    • Koshkaryev A, Thekkedath R, Pagano C, et al. Targeting of lysosomes by liposomes modified with octadecyl-rhodamine B. Journal Drug Targeting 2011; 19 (8): 606-14
    • (2011) Journal Drug Targeting , vol.19 , Issue.8 , pp. 606-614
    • Koshkaryev, A.1    Thekkedath, R.2    Pagano, C.3
  • 163
    • 84879624770 scopus 로고    scopus 로고
    • Lysosome-Targeted octadecyl-rhodamine B-liposomes enhance lysosomal accumulation of glucocerebrosidase in Gauchers cells in vitro
    • Thekkedath R, Koshkaryev A, Torchilin VP. Lysosome-Targeted octadecyl-rhodamine B-liposomes enhance lysosomal accumulation of glucocerebrosidase in Gauchers cells in vitro. Nanomedicine (Lond) 2013; 8 (7): 1055-65
    • (2013) Nanomedicine (Lond) , vol.8 , Issue.7 , pp. 1055-1065
    • Thekkedath, R.1    Koshkaryev, A.2    Torchilin, V.P.3
  • 164
    • 84862680834 scopus 로고    scopus 로고
    • Enhanced delivery of alpha-glucosidase for Pompe disease by ICAM-1-Targeted nanocarriers: Comparative performance of a strategy for three distinct lysosomal storage disorders
    • Hsu J, Northrup L, Bhowmick T, et al. Enhanced delivery of alpha-glucosidase for Pompe disease by ICAM-1-Targeted nanocarriers: comparative performance of a strategy for three distinct lysosomal storage disorders. Nanomed 2012; 8 (5): 731-9
    • (2012) Nanomed , vol.8 , Issue.5 , pp. 731-739
    • Hsu, J.1    Northrup, L.2    Bhowmick, T.3
  • 165
    • 79951920175 scopus 로고    scopus 로고
    • Enhanced endothelial delivery and biochemical effects of alpha-galactosidase by ICAM-1-Targeted nanocarriers for Fabry disease
    • Hsu J, Serrano D, Bhowmick T, et al. Enhanced endothelial delivery and biochemical effects of alpha-galactosidase by ICAM-1-Targeted nanocarriers for Fabry disease. J Controlled Release 2011; 149 (3): 323-31
    • (2011) J Controlled Release , vol.149 , Issue.3 , pp. 323-331
    • Hsu, J.1    Serrano, D.2    Bhowmick, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.