Enzyme-responsive cell-penetrating peptide conjugated mesoporous silica quantum dot nanocarriers for controlled release of nucleus-targeted drug molecules and real-time intracellular fluorescence imaging of tumor cells

Advanced Healthcare Materials

Volumn 3, Issue 8, 2014, Pages 1230-1239

  Li, Jinming ^a   Liu, Fang ^a   Shao, Qing ^a   Min, Yuanzeng ^a   Costa, Marianne ^a   Yeow, Edwin K L ^a   Xing, Bengang ^a  

^a Nanyang Technological University   (Singapore)

Author keywords

Cell penetrating peptides; Enzyme responsive; Intracellular imaging; Mesoporous quantum dots; Nucleus targeted delivery

Indexed keywords

CELLS; CONTROLLED DRUG DELIVERY; CYTOLOGY; ENZYMES; FLUORESCENCE IMAGING; MESOPOROUS MATERIALS; MOLECULES; NANOCRYSTALS; NANOPARTICLES; PEPTIDES; SEMICONDUCTOR QUANTUM DOTS; SILICA; TUMORS;

ACTIVATABLE CELL PENETRATING PEPTIDES; ANTI-TUMOR ACTIVITIES; ANTITUMOR DRUG DELIVERIES; CELL-PENETRATING PEPTIDE; INTRACELLULAR FLUORESCENCE; INTRACELLULAR IMAGING; MESOPOROUS; TARGETED DELIVERY;

TARGETED DRUG DELIVERY;

CATHEPSIN B; CELL PENETRATING PEPTIDE; DOXORUBICIN; NANOCARRIER; QUANTUM DOT; SILICON DIOXIDE; ANTINEOPLASTIC AGENT; DELAYED RELEASE FORMULATION; DRUG CARRIER;

ARTICLE; CELL NUCLEUS; CELL VIABILITY; CONFOCAL LASER MICROSCOPY; CONJUGATION; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG CYTOTOXICITY; DRUG TARGETING; FLUORESCENCE IMAGING; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR CELL; 3T3 CELL LINE; AMINO ACID SEQUENCE; ANIMAL; CELL SURVIVAL; CHEMISTRY; CONFOCAL MICROSCOPY; DELAYED RELEASE FORMULATION; DRUG EFFECTS; HUMAN; METABOLISM; MOUSE; POROSITY; TUMOR CELL LINE;

AMINO ACID SEQUENCE; ANIMALS; ANTINEOPLASTIC AGENTS; CATHEPSIN B; CELL LINE, TUMOR; CELL NUCLEUS; CELL SURVIVAL; CELL-PENETRATING PEPTIDES; DELAYED-ACTION PREPARATIONS; DOXORUBICIN; DRUG CARRIERS; HUMANS; MICE; MICROSCOPY, CONFOCAL; NIH 3T3 CELLS; POROSITY; QUANTUM DOTS; SILICON DIOXIDE;

EID: 84906087666     PISSN: 21922640     EISSN: 21922659     Source Type: Journal    
DOI: 10.1002/adhm.201300613     Document Type: Article

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