-
1
-
-
0011909346
-
Macromolecular therapeutics: emerging strategies for drug discovery in the postgenome era
-
Juliano R.L., Astriab-Fisher A., and Falke D. Macromolecular therapeutics: emerging strategies for drug discovery in the postgenome era. Mol. Interv. 1 (2001) 40-53
-
(2001)
Mol. Interv.
, vol.1
, pp. 40-53
-
-
Juliano, R.L.1
Astriab-Fisher, A.2
Falke, D.3
-
2
-
-
0141907718
-
Destination 'lysosome': a target organelle for tumour cell killing?
-
Castino R., Demoz M., and Isidoro C. Destination 'lysosome': a target organelle for tumour cell killing?. J. Mol. Recognit. 16 (2003) 337-348
-
(2003)
J. Mol. Recognit.
, vol.16
, pp. 337-348
-
-
Castino, R.1
Demoz, M.2
Isidoro, C.3
-
3
-
-
33746579876
-
Targeting the role of the endosome in the pathophysiology of Alzheimer's disease: a strategy for treatment
-
Tate B.A., and Mathews P.M. Targeting the role of the endosome in the pathophysiology of Alzheimer's disease: a strategy for treatment. Sci. Aging Knowl. Environ. 2006 (2006) re2
-
(2006)
Sci. Aging Knowl. Environ.
, vol.2006
-
-
Tate, B.A.1
Mathews, P.M.2
-
4
-
-
0037197831
-
Brain-directed gene therapy for lysosomal storage disease: going well beyond the blood-brain barrier
-
Sly W.S., and Vogler C. Brain-directed gene therapy for lysosomal storage disease: going well beyond the blood-brain barrier. Proc. Natl. Acad. Sci. U. S. A. 99 (2002) 5760-5762
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 5760-5762
-
-
Sly, W.S.1
Vogler, C.2
-
5
-
-
0037072555
-
Folate-mediated delivery of macromolecular anticancer therapeutic agents
-
Lu Y., and Low P.S. Folate-mediated delivery of macromolecular anticancer therapeutic agents. Adv. Drug Deliv. Rev. 54 (2002) 675-693
-
(2002)
Adv. Drug Deliv. Rev.
, vol.54
, pp. 675-693
-
-
Lu, Y.1
Low, P.S.2
-
6
-
-
33646798446
-
A mechanistic study of enhanced doxorubicin uptake and retention in multidrug resistant breast cancer cells using a polymer-lipid hybrid nanoparticle system
-
Wong H.L., Bendayan R., Rauth A.M., Xue H.Y., Babakhanian K., and Wu X.Y. A mechanistic study of enhanced doxorubicin uptake and retention in multidrug resistant breast cancer cells using a polymer-lipid hybrid nanoparticle system. J. Pharmacol. Exp. Ther. 317 (2006) 1372-1381
-
(2006)
J. Pharmacol. Exp. Ther.
, vol.317
, pp. 1372-1381
-
-
Wong, H.L.1
Bendayan, R.2
Rauth, A.M.3
Xue, H.Y.4
Babakhanian, K.5
Wu, X.Y.6
-
8
-
-
0346670126
-
Clathrin and caveolin-1 expression in primary pigmented rabbit conjunctival epithelial cells: role in PLGA nanoparticle endocytosis
-
Qaddoumi M.G., Gukasyan H.J., Davda J., Labhasetwar V., Kim K.J., and Lee V.H. Clathrin and caveolin-1 expression in primary pigmented rabbit conjunctival epithelial cells: role in PLGA nanoparticle endocytosis. Mol. Vis. 9 (2003) 559-568
-
(2003)
Mol. Vis.
, vol.9
, pp. 559-568
-
-
Qaddoumi, M.G.1
Gukasyan, H.J.2
Davda, J.3
Labhasetwar, V.4
Kim, K.J.5
Lee, V.H.6
-
9
-
-
33750957656
-
Cytoskeletal scaffolds regulate riboflavin endocytosis and recycling in placental trophoblasts
-
D'Souza V.M., Bareford L.M., Ray A., and Swaan P.W. Cytoskeletal scaffolds regulate riboflavin endocytosis and recycling in placental trophoblasts. J. Nutr. Biochem. 17 (2006) 821-829
-
(2006)
J. Nutr. Biochem.
, vol.17
, pp. 821-829
-
-
D'Souza, V.M.1
Bareford, L.M.2
Ray, A.3
Swaan, P.W.4
-
10
-
-
0037147281
-
Structure of the LDL receptor extracellular domain at endosomal pH
-
Rudenko G., Henry L., Henderson K., Ichtchenko K., Brown M.S., Goldstein J.L., and Deisenhofer J. Structure of the LDL receptor extracellular domain at endosomal pH. Science 298 (2002) 2353-2358
-
(2002)
Science
, vol.298
, pp. 2353-2358
-
-
Rudenko, G.1
Henry, L.2
Henderson, K.3
Ichtchenko, K.4
Brown, M.S.5
Goldstein, J.L.6
Deisenhofer, J.7
-
11
-
-
0038402693
-
Mannose receptor-mediated gene delivery into antigen presenting dendritic cells
-
Diebold S.S., Plank C., Cotten M., Wagner E., and Zenke M. Mannose receptor-mediated gene delivery into antigen presenting dendritic cells. Somat. Cell Mol. Genet. 27 (2002) 65-74
-
(2002)
Somat. Cell Mol. Genet.
, vol.27
, pp. 65-74
-
-
Diebold, S.S.1
Plank, C.2
Cotten, M.3
Wagner, E.4
Zenke, M.5
-
12
-
-
0033564268
-
Targeted delivery of oligodeoxynucleotides to parenchymal liver cells in vivo
-
Biessen E.A., Vietsch H., Rump E.T., Fluiter K., Kuiper J., Bijsterbosch M.K., and van Berkel T.J. Targeted delivery of oligodeoxynucleotides to parenchymal liver cells in vivo. Biochem. J. 340 Pt 3 (1999) 783-792
-
(1999)
Biochem. J.
, vol.340
, Issue.PART 3
, pp. 783-792
-
-
Biessen, E.A.1
Vietsch, H.2
Rump, E.T.3
Fluiter, K.4
Kuiper, J.5
Bijsterbosch, M.K.6
van Berkel, T.J.7
-
13
-
-
0037731636
-
Epidermal growth factor receptor (EGFR)-targeted immunoliposomes mediate specific and efficient drug delivery to EGFR- and EGFRvIII-overexpressing tumor cells
-
Mamot C., Drummond D.C., Greiser U., Hong K., Kirpotin D.B., Marks J.D., and Park J.W. Epidermal growth factor receptor (EGFR)-targeted immunoliposomes mediate specific and efficient drug delivery to EGFR- and EGFRvIII-overexpressing tumor cells. Cancer Res. 63 (2003) 3154-3161
-
(2003)
Cancer Res.
, vol.63
, pp. 3154-3161
-
-
Mamot, C.1
Drummond, D.C.2
Greiser, U.3
Hong, K.4
Kirpotin, D.B.5
Marks, J.D.6
Park, J.W.7
-
14
-
-
4644274938
-
Chemokine receptor-mediated delivery directs self-tumor antigen efficiently into the class II processing pathway in vitro and induces protective immunity in vivo
-
Biragyn A., Ruffini P.A., Coscia M., Harvey L.K., Neelapu S.S., Baskar S., Wang J.M., and Kwak L.W. Chemokine receptor-mediated delivery directs self-tumor antigen efficiently into the class II processing pathway in vitro and induces protective immunity in vivo. Blood 104 (2004) 1961-1969
-
(2004)
Blood
, vol.104
, pp. 1961-1969
-
-
Biragyn, A.1
Ruffini, P.A.2
Coscia, M.3
Harvey, L.K.4
Neelapu, S.S.5
Baskar, S.6
Wang, J.M.7
Kwak, L.W.8
-
15
-
-
0345714785
-
Current perspectives on the cellular uptake and trafficking of riboflavin
-
Foraker A.B., Khantwal C.M., and Swaan P.W. Current perspectives on the cellular uptake and trafficking of riboflavin. Adv. Drug Deliv. Rev. 55 (2003) 1467-1483
-
(2003)
Adv. Drug Deliv. Rev.
, vol.55
, pp. 1467-1483
-
-
Foraker, A.B.1
Khantwal, C.M.2
Swaan, P.W.3
-
16
-
-
33645781775
-
Targeted brain delivery of AZT via transferrin anchored pegylated albumin nanoparticles
-
Mishra V., Mahor S., Rawat A., Gupta P.N., Dubey P., Khatri K., and Vyas S.P. Targeted brain delivery of AZT via transferrin anchored pegylated albumin nanoparticles. J. Drug Target. 14 (2006) 45-53
-
(2006)
J. Drug Target.
, vol.14
, pp. 45-53
-
-
Mishra, V.1
Mahor, S.2
Rawat, A.3
Gupta, P.N.4
Dubey, P.5
Khatri, K.6
Vyas, S.P.7
-
17
-
-
0036889760
-
Targeted drug delivery via the transferrin receptor-mediated endocytosis pathway
-
Qian Z.M., Li H., Sun H., and Ho K. Targeted drug delivery via the transferrin receptor-mediated endocytosis pathway. Pharmacol. Rev. 54 (2002) 561-587
-
(2002)
Pharmacol. Rev.
, vol.54
, pp. 561-587
-
-
Qian, Z.M.1
Li, H.2
Sun, H.3
Ho, K.4
-
18
-
-
0032718104
-
Elevation of serum riboflavin carrier protein in breast cancer
-
Rao P.N., Levine E., Myers M.O., Prakash V., Watson J., Stolier A., Kopicko J.J., Kissinger P., Raj S.G., and Raj M.H. Elevation of serum riboflavin carrier protein in breast cancer. Cancer Epidemiol. Biomark. Prev. 8 (1999) 985-990
-
(1999)
Cancer Epidemiol. Biomark. Prev.
, vol.8
, pp. 985-990
-
-
Rao, P.N.1
Levine, E.2
Myers, M.O.3
Prakash, V.4
Watson, J.5
Stolier, A.6
Kopicko, J.J.7
Kissinger, P.8
Raj, S.G.9
Raj, M.H.10
-
19
-
-
33748922791
-
Cell adhesion molecules for targeted drug delivery
-
Dunehoo A.L., Anderson M., Majumdar S., Kobayashi N., Berkland C., and Siahaan T.J. Cell adhesion molecules for targeted drug delivery. J. Pharm. Sci. 95 (2006) 1856-1872
-
(2006)
J. Pharm. Sci.
, vol.95
, pp. 1856-1872
-
-
Dunehoo, A.L.1
Anderson, M.2
Majumdar, S.3
Kobayashi, N.4
Berkland, C.5
Siahaan, T.J.6
-
20
-
-
28844463125
-
Lysosomal enzyme delivery by ICAM-1-targeted nanocarriers bypassing glycosylation- and clathrin-dependent endocytosis
-
Muro S., Schuchman E.H., and Muzykantov V.R. Lysosomal enzyme delivery by ICAM-1-targeted nanocarriers bypassing glycosylation- and clathrin-dependent endocytosis. Molec. Ther. 13 (2006) 135-141
-
(2006)
Molec. Ther.
, vol.13
, pp. 135-141
-
-
Muro, S.1
Schuchman, E.H.2
Muzykantov, V.R.3
-
21
-
-
11244353770
-
ICAM-1 recycling in endothelial cells: a novel pathway for sustained intracellular delivery and prolonged effects of drugs
-
Muro S., Gajewski C., Koval M., and Muzykantov V.R. ICAM-1 recycling in endothelial cells: a novel pathway for sustained intracellular delivery and prolonged effects of drugs. Blood 105 (2005) 650-658
-
(2005)
Blood
, vol.105
, pp. 650-658
-
-
Muro, S.1
Gajewski, C.2
Koval, M.3
Muzykantov, V.R.4
-
22
-
-
0030925772
-
Differences between fluid-phase endocytosis (pinocytosis) and receptor-mediated endocytosis in isolated rat hepatocytes
-
Stromhaug P.E., Berg T.O., Gjoen T., and Seglen P.O. Differences between fluid-phase endocytosis (pinocytosis) and receptor-mediated endocytosis in isolated rat hepatocytes. Eur. J. Cell Biol. 73 (1997) 28-39
-
(1997)
Eur. J. Cell Biol.
, vol.73
, pp. 28-39
-
-
Stromhaug, P.E.1
Berg, T.O.2
Gjoen, T.3
Seglen, P.O.4
-
23
-
-
3242715122
-
Technetium-99m-labeled N-(2-hydroxypropyl) methacrylamide copolymers: synthesis, characterization, and in vivo biodistribution
-
Mitra A., Nan A., Ghandehari H., McNeill E., Mulholland J., and Line B.R. Technetium-99m-labeled N-(2-hydroxypropyl) methacrylamide copolymers: synthesis, characterization, and in vivo biodistribution. Pharm. Res. 21 (2004) 1153-1159
-
(2004)
Pharm. Res.
, vol.21
, pp. 1153-1159
-
-
Mitra, A.1
Nan, A.2
Ghandehari, H.3
McNeill, E.4
Mulholland, J.5
Line, B.R.6
-
24
-
-
0024847554
-
Increase of poly(l-lysine) uptake but not fluid phase endocytosis in neuraminidase pretreated Madin-Darby canine kidney (MDCK) cells
-
Persiani S., and Shen W.C. Increase of poly(l-lysine) uptake but not fluid phase endocytosis in neuraminidase pretreated Madin-Darby canine kidney (MDCK) cells. Life Sci. 45 (1989) 2605-2610
-
(1989)
Life Sci.
, vol.45
, pp. 2605-2610
-
-
Persiani, S.1
Shen, W.C.2
-
25
-
-
0026980122
-
Targeted delivery of human recombinant superoxide dismutase by chemical modification with mono- and polysaccharide derivatives
-
Fujita T., Nishikawa M., Tamaki C., Takakura Y., Hashida M., and Sezaki H. Targeted delivery of human recombinant superoxide dismutase by chemical modification with mono- and polysaccharide derivatives. J. Pharmacol. Exp. Ther. 263 (1992) 971-978
-
(1992)
J. Pharmacol. Exp. Ther.
, vol.263
, pp. 971-978
-
-
Fujita, T.1
Nishikawa, M.2
Tamaki, C.3
Takakura, Y.4
Hashida, M.5
Sezaki, H.6
-
26
-
-
0036015564
-
Indole-3-acetic acids and horseradish peroxidase: a new prodrug/enzyme combination for targeted cancer therapy
-
Wardman P. Indole-3-acetic acids and horseradish peroxidase: a new prodrug/enzyme combination for targeted cancer therapy. Curr. Pharm. Des. 8 (2002) 1363-1374
-
(2002)
Curr. Pharm. Des.
, vol.8
, pp. 1363-1374
-
-
Wardman, P.1
-
27
-
-
0021807555
-
Endocytosis of cationized ferritin in human peripheral blood by resting T-lymphocytes
-
Renau-Piqueras J., Miragall F., and Cervera J. Endocytosis of cationized ferritin in human peripheral blood by resting T-lymphocytes. Cell Tissue Res. 240 (1985) 743-746
-
(1985)
Cell Tissue Res.
, vol.240
, pp. 743-746
-
-
Renau-Piqueras, J.1
Miragall, F.2
Cervera, J.3
-
28
-
-
0033934883
-
Involvement of a receptor-mediated component in cellular translocation of riboflavin
-
Huang S.N., and Swaan P.W. Involvement of a receptor-mediated component in cellular translocation of riboflavin. J. Pharmacol. Exp. Ther. 294 (2000) 117-125
-
(2000)
J. Pharmacol. Exp. Ther.
, vol.294
, pp. 117-125
-
-
Huang, S.N.1
Swaan, P.W.2
-
29
-
-
0035265834
-
Interleukin 2 receptors and detergent-resistant membrane domains define a clathrin-independent endocytic pathway
-
Lamaze C., Dujeancourt A., Baba T., Lo C.G., Benmerah A., and Dautry-Varsat A. Interleukin 2 receptors and detergent-resistant membrane domains define a clathrin-independent endocytic pathway. Mol. Cell 7 (2001) 661-671
-
(2001)
Mol. Cell
, vol.7
, pp. 661-671
-
-
Lamaze, C.1
Dujeancourt, A.2
Baba, T.3
Lo, C.G.4
Benmerah, A.5
Dautry-Varsat, A.6
-
30
-
-
0035017308
-
Caveolar endocytosis of simian virus 40 reveals a new two-step vesicular-transport pathway to the ER
-
Pelkmans L., Kartenbeck J., and Helenius A. Caveolar endocytosis of simian virus 40 reveals a new two-step vesicular-transport pathway to the ER. Nat. Cell Biol. 3 (2001) 473-483
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 473-483
-
-
Pelkmans, L.1
Kartenbeck, J.2
Helenius, A.3
-
31
-
-
0036239115
-
Endocytosis via caveolae
-
Pelkmans L., and Helenius A. Endocytosis via caveolae. Traffic 3 (2002) 311-320
-
(2002)
Traffic
, vol.3
, pp. 311-320
-
-
Pelkmans, L.1
Helenius, A.2
-
32
-
-
0026625261
-
Lowering the cholesterol content of MA104 cells inhibits receptor-mediated transport of folate
-
Chang W.J., Rothberg K.G., Kamen B.A., and Anderson R.G. Lowering the cholesterol content of MA104 cells inhibits receptor-mediated transport of folate. J. Cell Biol. 118 (1992) 63-69
-
(1992)
J. Cell Biol.
, vol.118
, pp. 63-69
-
-
Chang, W.J.1
Rothberg, K.G.2
Kamen, B.A.3
Anderson, R.G.4
-
33
-
-
0036071884
-
Intracellular delivery of nanometric DNA particles via the folate receptor
-
Dauty E., Remy J.S., Zuber G., and Behr J.P. Intracellular delivery of nanometric DNA particles via the folate receptor. Bioconjug. Chem. 13 (2002) 831-839
-
(2002)
Bioconjug. Chem.
, vol.13
, pp. 831-839
-
-
Dauty, E.1
Remy, J.S.2
Zuber, G.3
Behr, J.P.4
-
34
-
-
0035963903
-
Caveolae: from basic trafficking mechanisms to targeting transcytosis for tissue-specific drug and gene delivery in vivo
-
Schnitzer J.E. Caveolae: from basic trafficking mechanisms to targeting transcytosis for tissue-specific drug and gene delivery in vivo. Adv. Drug Deliv. Rev. 49 (2001) 265-280
-
(2001)
Adv. Drug Deliv. Rev.
, vol.49
, pp. 265-280
-
-
Schnitzer, J.E.1
-
35
-
-
0038402594
-
Design and synthesis of pH-responsive polymeric carriers that target uptake and enhance the intracellular delivery of oligonucleotides
-
Murthy N., Campbell J., Fausto N., Hoffman A.S., and Stayton P.S. Design and synthesis of pH-responsive polymeric carriers that target uptake and enhance the intracellular delivery of oligonucleotides. J. Control. Release 89 (2003) 365-374
-
(2003)
J. Control. Release
, vol.89
, pp. 365-374
-
-
Murthy, N.1
Campbell, J.2
Fausto, N.3
Hoffman, A.S.4
Stayton, P.S.5
-
38
-
-
0036094927
-
A distinct class of endosome mediates clathrin-independent endocytosis to the Golgi complex
-
Nichols B.J. A distinct class of endosome mediates clathrin-independent endocytosis to the Golgi complex. Nat. Cell Biol. 4 (2002) 374-378
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 374-378
-
-
Nichols, B.J.1
-
39
-
-
0031750101
-
Filipin-dependent inhibition of cholera toxin: evidence for toxin internalization and activation through caveolae-like domains
-
Orlandi P.A., and Fishman P.H. Filipin-dependent inhibition of cholera toxin: evidence for toxin internalization and activation through caveolae-like domains. J. Cell Biol. 141 (1998) 905-915
-
(1998)
J. Cell Biol.
, vol.141
, pp. 905-915
-
-
Orlandi, P.A.1
Fishman, P.H.2
-
40
-
-
0030949124
-
Functional rafts in cell membranes
-
Simons K., and Ikonen E. Functional rafts in cell membranes. Nature 387 (1997) 569-572
-
(1997)
Nature
, vol.387
, pp. 569-572
-
-
Simons, K.1
Ikonen, E.2
-
41
-
-
0029153663
-
Conjugation of cholera toxin or its B subunit to liposomes for targeted delivery of antigens
-
Harokopakis E., Childers N.K., Michalek S.M., Zhang S.S., and Tomasi M. Conjugation of cholera toxin or its B subunit to liposomes for targeted delivery of antigens. J. Immunol. Methods 185 (1995) 31-42
-
(1995)
J. Immunol. Methods
, vol.185
, pp. 31-42
-
-
Harokopakis, E.1
Childers, N.K.2
Michalek, S.M.3
Zhang, S.S.4
Tomasi, M.5
-
42
-
-
27744606539
-
The alpha- and beta-subunits of the human UDP-N-acetylglucosamine:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase [corrected] are encoded by a single cDNA
-
Kudo M., Bao M., D'Souza A., Ying F., Pan H., Roe B.A., and Canfield W.M. The alpha- and beta-subunits of the human UDP-N-acetylglucosamine:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase [corrected] are encoded by a single cDNA. J. Biol. Chem. 280 (2005) 36141-36149
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 36141-36149
-
-
Kudo, M.1
Bao, M.2
D'Souza, A.3
Ying, F.4
Pan, H.5
Roe, B.A.6
Canfield, W.M.7
-
43
-
-
34248578374
-
Autophagy, mitochondria and cell death in lysosomal storage diseases
-
Kiselyov K., Jennigs Jr. J.J., Rbaibi Y., and Chu C.T. Autophagy, mitochondria and cell death in lysosomal storage diseases. Autophagy 3 (2007)
-
(2007)
Autophagy
, vol.3
-
-
Kiselyov, K.1
Jennigs Jr., J.J.2
Rbaibi, Y.3
Chu, C.T.4
-
44
-
-
26844534412
-
Overcoming the blood-brain barrier with high-dose enzyme replacement therapy in murine mucopolysaccharidosis VII
-
Vogler C., Levy B., Grubb J.H., Galvin N., Tan Y., Kakkis E., Pavloff N., and Sly W.S. Overcoming the blood-brain barrier with high-dose enzyme replacement therapy in murine mucopolysaccharidosis VII. Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 14777-14782
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 14777-14782
-
-
Vogler, C.1
Levy, B.2
Grubb, J.H.3
Galvin, N.4
Tan, Y.5
Kakkis, E.6
Pavloff, N.7
Sly, W.S.8
-
45
-
-
33646594456
-
cAMP-coupled riboflavin trafficking in placental trophoblasts: a dynamic and ordered process
-
D'Souza V.M., Foraker A.B., Free R.B., Ray A., Shapiro P.S., and Swaan P.W. cAMP-coupled riboflavin trafficking in placental trophoblasts: a dynamic and ordered process. Biochemistry 45 (2006) 6095-6104
-
(2006)
Biochemistry
, vol.45
, pp. 6095-6104
-
-
D'Souza, V.M.1
Foraker, A.B.2
Free, R.B.3
Ray, A.4
Shapiro, P.S.5
Swaan, P.W.6
-
46
-
-
0022400508
-
Transit of receptors for epidermal growth factor and transferrin through clathrin-coated pits. Analysis of the kinetics of receptor entry
-
Hanover J.A., Beguinot L., Willingham M.C., and Pastan I.H. Transit of receptors for epidermal growth factor and transferrin through clathrin-coated pits. Analysis of the kinetics of receptor entry. J. Biol. Chem. 260 (1985) 15938-15945
-
(1985)
J. Biol. Chem.
, vol.260
, pp. 15938-15945
-
-
Hanover, J.A.1
Beguinot, L.2
Willingham, M.C.3
Pastan, I.H.4
-
47
-
-
0030711713
-
Alzheimer's disease. The ins and outs of amyloid-beta
-
Beyreuther K., and Masters C.L. Alzheimer's disease. The ins and outs of amyloid-beta. Nature 389 (1997) 677-678
-
(1997)
Nature
, vol.389
, pp. 677-678
-
-
Beyreuther, K.1
Masters, C.L.2
-
48
-
-
0034304390
-
The endosomal-lysosomal system of neurons in Alzheimer's disease pathogenesis: a review
-
Nixon R.A., Cataldo A.M., and Mathews P.M. The endosomal-lysosomal system of neurons in Alzheimer's disease pathogenesis: a review. Neurochem. Res. 25 (2000) 1161-1172
-
(2000)
Neurochem. Res.
, vol.25
, pp. 1161-1172
-
-
Nixon, R.A.1
Cataldo, A.M.2
Mathews, P.M.3
-
49
-
-
0642316039
-
Nerve growth factor: structure, function and therapeutic implications for Alzheimer's disease
-
Lad S.P., Neet K.E., and Mufson E.J. Nerve growth factor: structure, function and therapeutic implications for Alzheimer's disease. Curr. Drug Targets CNS Neurol. Disord. 2 (2003) 315-334
-
(2003)
Curr. Drug Targets CNS Neurol. Disord.
, vol.2
, pp. 315-334
-
-
Lad, S.P.1
Neet, K.E.2
Mufson, E.J.3
-
50
-
-
0037138438
-
Lysosomal proteases as potential targets for the induction of apoptotic cell death in human neuroblastomas
-
Castino R., Pace D., Demoz M., Gargiulo M., Ariatta C., Raiteri E., and Isidoro C. Lysosomal proteases as potential targets for the induction of apoptotic cell death in human neuroblastomas. Int. J. Cancer 97 (2002) 775-779
-
(2002)
Int. J. Cancer
, vol.97
, pp. 775-779
-
-
Castino, R.1
Pace, D.2
Demoz, M.3
Gargiulo, M.4
Ariatta, C.5
Raiteri, E.6
Isidoro, C.7
-
51
-
-
0037184909
-
Taking the study of cancer cell survival to a new dimension
-
Jacks T., and Weinberg R.A. Taking the study of cancer cell survival to a new dimension. Cell 111 (2002) 923-925
-
(2002)
Cell
, vol.111
, pp. 923-925
-
-
Jacks, T.1
Weinberg, R.A.2
-
52
-
-
18444380859
-
Photochemical internalisation: a novel drug delivery system
-
Selbo P.K., Hogset A., Prasmickaite L., and Berg K. Photochemical internalisation: a novel drug delivery system. Tumour Biol. 23 (2002) 103-112
-
(2002)
Tumour Biol.
, vol.23
, pp. 103-112
-
-
Selbo, P.K.1
Hogset, A.2
Prasmickaite, L.3
Berg, K.4
-
53
-
-
13844269029
-
Polymeric micellar pH-sensitive drug delivery system for doxorubicin
-
Hruby M., Konak C., and Ulbrich K. Polymeric micellar pH-sensitive drug delivery system for doxorubicin. J. Control. Release 103 (2005) 137-148
-
(2005)
J. Control. Release
, vol.103
, pp. 137-148
-
-
Hruby, M.1
Konak, C.2
Ulbrich, K.3
-
54
-
-
18244399644
-
Photochemical disruption of endocytic vesicles before delivery of drugs: a new strategy for cancer therapy
-
Prasmickaite L., Hogset A., Selbo P.K., Engesaeter B.O., Hellum M., and Berg K. Photochemical disruption of endocytic vesicles before delivery of drugs: a new strategy for cancer therapy. Br. J. Cancer 86 (2002) 652-657
-
(2002)
Br. J. Cancer
, vol.86
, pp. 652-657
-
-
Prasmickaite, L.1
Hogset, A.2
Selbo, P.K.3
Engesaeter, B.O.4
Hellum, M.5
Berg, K.6
-
55
-
-
21644459862
-
Transferrin-oligomers as potential carriers in anticancer drug delivery
-
Lim C.J., and Shen W.C. Transferrin-oligomers as potential carriers in anticancer drug delivery. Pharm. Res. 21 (2004) 1985-1992
-
(2004)
Pharm. Res.
, vol.21
, pp. 1985-1992
-
-
Lim, C.J.1
Shen, W.C.2
-
56
-
-
0025340966
-
Transferrin-polycation conjugates as carriers for DNA uptake into cells
-
Wagner E., Zenke M., Cotten M., Beug H., and Birnstiel M.L. Transferrin-polycation conjugates as carriers for DNA uptake into cells. Proc. Natl. Acad. Sci. U. S. A. 87 (1990) 3410-3414
-
(1990)
Proc. Natl. Acad. Sci. U. S. A.
, vol.87
, pp. 3410-3414
-
-
Wagner, E.1
Zenke, M.2
Cotten, M.3
Beug, H.4
Birnstiel, M.L.5
-
57
-
-
0036245040
-
Pharmacokinetics and brain uptake of biotinylated basic fibroblast growth factor conjugated to a blood-brain barrier drug delivery system
-
Wu D., Song B.W., Vinters H.V., and Pardridge W.M. Pharmacokinetics and brain uptake of biotinylated basic fibroblast growth factor conjugated to a blood-brain barrier drug delivery system. J. Drug Target. 10 (2002) 239-245
-
(2002)
J. Drug Target.
, vol.10
, pp. 239-245
-
-
Wu, D.1
Song, B.W.2
Vinters, H.V.3
Pardridge, W.M.4
-
58
-
-
0027318762
-
Binding, internalization, and degradation of mannose-terminated glucocerebrosidase by macrophages
-
Sato Y., and Beutler E. Binding, internalization, and degradation of mannose-terminated glucocerebrosidase by macrophages. J. Clin. Invest. 91 (1993) 1909-1917
-
(1993)
J. Clin. Invest.
, vol.91
, pp. 1909-1917
-
-
Sato, Y.1
Beutler, E.2
-
59
-
-
0028248444
-
A polymeric drug delivery system for the simultaneous delivery of drugs activatable by enzymes and/or light
-
Krinick N.L., Sun Y., Joyner D., Spikes J.D., Straight R.C., and Kopecek J. A polymeric drug delivery system for the simultaneous delivery of drugs activatable by enzymes and/or light. J. Biomater. Sci., Polym. Ed. 5 (1994) 303-324
-
(1994)
J. Biomater. Sci., Polym. Ed.
, vol.5
, pp. 303-324
-
-
Krinick, N.L.1
Sun, Y.2
Joyner, D.3
Spikes, J.D.4
Straight, R.C.5
Kopecek, J.6
-
60
-
-
0027469593
-
Decreased expression of the human folate receptor mediates transport-defective methotrexate resistance in KB cells
-
Saikawa Y., Knight C.B., Saikawa T., Page S.T., Chabner B.A., and Elwood P.C. Decreased expression of the human folate receptor mediates transport-defective methotrexate resistance in KB cells. J. Biol. Chem. 268 (1993) 5293-5301
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 5293-5301
-
-
Saikawa, Y.1
Knight, C.B.2
Saikawa, T.3
Page, S.T.4
Chabner, B.A.5
Elwood, P.C.6
-
61
-
-
9444279605
-
Ligand binding and kinetics of folate receptor recycling in vivo: impact on receptor-mediated drug delivery
-
Paulos C.M., Reddy J.A., Leamon C.P., Turk M.J., and Low P.S. Ligand binding and kinetics of folate receptor recycling in vivo: impact on receptor-mediated drug delivery. Mol. Pharmacol. 66 (2004) 1406-1414
-
(2004)
Mol. Pharmacol.
, vol.66
, pp. 1406-1414
-
-
Paulos, C.M.1
Reddy, J.A.2
Leamon, C.P.3
Turk, M.J.4
Low, P.S.5
-
62
-
-
0037742256
-
Selective delivery of CB300638, a cyclopenta[g]quinazoline-based thymidylate synthase inhibitor into human tumor cell lines overexpressing the alpha-isoform of the folate receptor
-
Theti D.S., Bavetsias V., Skelton L.A., Titley J., Gibbs D., Jansen G., and Jackman A.L. Selective delivery of CB300638, a cyclopenta[g]quinazoline-based thymidylate synthase inhibitor into human tumor cell lines overexpressing the alpha-isoform of the folate receptor. Cancer Res. 63 (2003) 3612-3618
-
(2003)
Cancer Res.
, vol.63
, pp. 3612-3618
-
-
Theti, D.S.1
Bavetsias, V.2
Skelton, L.A.3
Titley, J.4
Gibbs, D.5
Jansen, G.6
Jackman, A.L.7
-
63
-
-
15244354054
-
Design, synthesis, and biological evaluation of folic acid targeted tetraphenylporphyrin as novel photosensitizers for selective photodynamic therapy
-
Schneider R., Schmitt F., Frochot C., Fort Y., Lourette N., Guillemin F., Muller J.F., and Barberi-Heyob M. Design, synthesis, and biological evaluation of folic acid targeted tetraphenylporphyrin as novel photosensitizers for selective photodynamic therapy. Bioorg. Med. Chem. 13 (2005) 2799-2808
-
(2005)
Bioorg. Med. Chem.
, vol.13
, pp. 2799-2808
-
-
Schneider, R.1
Schmitt, F.2
Frochot, C.3
Fort, Y.4
Lourette, N.5
Guillemin, F.6
Muller, J.F.7
Barberi-Heyob, M.8
-
64
-
-
29144450682
-
Rerouting lipoprotein nanoparticles to selected alternate receptors for the targeted delivery of cancer diagnostic and therapeutic agents
-
Zheng G., Chen J., Li H., and Glickson J.D. Rerouting lipoprotein nanoparticles to selected alternate receptors for the targeted delivery of cancer diagnostic and therapeutic agents. Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 17757-17762
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 17757-17762
-
-
Zheng, G.1
Chen, J.2
Li, H.3
Glickson, J.D.4
-
65
-
-
0031669047
-
Effectiveness of liposomes possessing surface-linked recombinant B subunit of cholera toxin as an oral antigen delivery system
-
Harokopakis E., Hajishengallis G., and Michalek S.M. Effectiveness of liposomes possessing surface-linked recombinant B subunit of cholera toxin as an oral antigen delivery system. Infect. Immun. 66 (1998) 4299-4304
-
(1998)
Infect. Immun.
, vol.66
, pp. 4299-4304
-
-
Harokopakis, E.1
Hajishengallis, G.2
Michalek, S.M.3
-
66
-
-
26244454363
-
Studies on the targeted delivery of the antifibrogenic compound mycophenolic acid to the hepatic stellate cell
-
Greupink R., Bakker H.I., Reker-Smit C., van Loenen-Weemaes A.M., Kok R.J., Meijer D.K., Beljaars L., and Poelstra K. Studies on the targeted delivery of the antifibrogenic compound mycophenolic acid to the hepatic stellate cell. J. Hepatol. 43 (2005) 884-892
-
(2005)
J. Hepatol.
, vol.43
, pp. 884-892
-
-
Greupink, R.1
Bakker, H.I.2
Reker-Smit, C.3
van Loenen-Weemaes, A.M.4
Kok, R.J.5
Meijer, D.K.6
Beljaars, L.7
Poelstra, K.8
-
67
-
-
0034075131
-
Targeted drug delivery to C6 glioma by transferrin-coupled liposomes
-
Eavarone D.A., Yu X., and Bellamkonda R.V. Targeted drug delivery to C6 glioma by transferrin-coupled liposomes. J. Biomed. Mater. Res. 51 (2000) 10-14
-
(2000)
J. Biomed. Mater. Res.
, vol.51
, pp. 10-14
-
-
Eavarone, D.A.1
Yu, X.2
Bellamkonda, R.V.3
-
68
-
-
1642457351
-
Anticancer drug delivery with transferrin targeted polymeric chitosan vesicles
-
Dufes C., Muller J.M., Couet W., Olivier J.C., Uchegbu I.F., and Schatzlein A.G. Anticancer drug delivery with transferrin targeted polymeric chitosan vesicles. Pharm. Res. 21 (2004) 101-107
-
(2004)
Pharm. Res.
, vol.21
, pp. 101-107
-
-
Dufes, C.1
Muller, J.M.2
Couet, W.3
Olivier, J.C.4
Uchegbu, I.F.5
Schatzlein, A.G.6
-
69
-
-
0032927596
-
Riboflavin-mediated delivery of a macromolecule into cultured human cells
-
Holladay S.R., Yang Z., Kennedy M.D., Leamon C.P., Lee R.J., Jayamani M., Mason T., and Low P.S. Riboflavin-mediated delivery of a macromolecule into cultured human cells. Biochim. Biophys. Acta 1426 (1999) 195-204
-
(1999)
Biochim. Biophys. Acta
, vol.1426
, pp. 195-204
-
-
Holladay, S.R.1
Yang, Z.2
Kennedy, M.D.3
Leamon, C.P.4
Lee, R.J.5
Jayamani, M.6
Mason, T.7
Low, P.S.8
-
70
-
-
33751520576
-
Nanocarriers for nuclear imaging and radiotherapy of cancer
-
Mitra A., Nan A., Line B.R., and Ghandehari H. Nanocarriers for nuclear imaging and radiotherapy of cancer. Curr. Pharm. Des. 12 (2006) 4729-4749
-
(2006)
Curr. Pharm. Des.
, vol.12
, pp. 4729-4749
-
-
Mitra, A.1
Nan, A.2
Line, B.R.3
Ghandehari, H.4
-
71
-
-
0034524889
-
Effect of nicotinic acid conjugated to DNA-transfecting complexes targeted at the transferrin receptor of HeLa cells
-
Quick G., van Zyl J., Hawtrey A., and Ariatti M. Effect of nicotinic acid conjugated to DNA-transfecting complexes targeted at the transferrin receptor of HeLa cells. Drug Deliv. 7 (2000) 231-236
-
(2000)
Drug Deliv.
, vol.7
, pp. 231-236
-
-
Quick, G.1
van Zyl, J.2
Hawtrey, A.3
Ariatti, M.4
-
72
-
-
0347382501
-
Receptor-mediated endocytosis by the asialoglycoprotein receptor: effect of ethanol administration on endosomal distribution of receptor and ligand
-
Dalton S.R., Wiegert R.L., and Casey C.A. Receptor-mediated endocytosis by the asialoglycoprotein receptor: effect of ethanol administration on endosomal distribution of receptor and ligand. Liver Int. 23 (2003) 484-491
-
(2003)
Liver Int.
, vol.23
, pp. 484-491
-
-
Dalton, S.R.1
Wiegert, R.L.2
Casey, C.A.3
|