-
1
-
-
34547877924
-
Mitochondrial medicine: pharmacological targeting of mitochondria in disease
-
Armstrong J.S. Mitochondrial medicine: pharmacological targeting of mitochondria in disease. Br. J. Pharmacol. 2007, 151:1154-1165.
-
(2007)
Br. J. Pharmacol.
, vol.151
, pp. 1154-1165
-
-
Armstrong, J.S.1
-
2
-
-
33748460635
-
Design of manganese porphyrin modified with mitochondrial signal peptide for a new antioxidant
-
Asayama S., Kawamura E., Nagaoka S., Kawakami H. Design of manganese porphyrin modified with mitochondrial signal peptide for a new antioxidant. Mol. Pharm. 2006, 3:468-470.
-
(2006)
Mol. Pharm.
, vol.3
, pp. 468-470
-
-
Asayama, S.1
Kawamura, E.2
Nagaoka, S.3
Kawakami, H.4
-
3
-
-
33745274726
-
Mitochondria: dynamic organelles in disease, aging, and development
-
Chan D.C. Mitochondria: dynamic organelles in disease, aging, and development. Cell 2006, 125:1241-1252.
-
(2006)
Cell
, vol.125
, pp. 1241-1252
-
-
Chan, D.C.1
-
4
-
-
49149124239
-
Nanocarrier-assisted sub-cellular targeting to the site of mitochondria improves the pro-apoptotic activity of paclitaxel
-
D'Souza G.G.M., Cheng S.M., Boddapati S.V., Horobin R.W., Weissig V. Nanocarrier-assisted sub-cellular targeting to the site of mitochondria improves the pro-apoptotic activity of paclitaxel. J. Drug Target. 2008, 16:578-585.
-
(2008)
J. Drug Target.
, vol.16
, pp. 578-585
-
-
D'Souza, G.G.M.1
Cheng, S.M.2
Boddapati, S.V.3
Horobin, R.W.4
Weissig, V.5
-
5
-
-
77649184822
-
Mitochondrial medicine for neurodegenerative diseases
-
Du H., Yan S.S.D. Mitochondrial medicine for neurodegenerative diseases. Int. J. Biochem. Cell Biol. 2010, 42:560-572.
-
(2010)
Int. J. Biochem. Cell Biol.
, vol.42
, pp. 560-572
-
-
Du, H.1
Yan, S.S.D.2
-
6
-
-
0028859492
-
Avidin fusion protein as a tool to generate a stable translocation intermediate spanning the mitochondrial membranes
-
Endo T., Nakayama Y., Nakai M. Avidin fusion protein as a tool to generate a stable translocation intermediate spanning the mitochondrial membranes. J. Biochem. (Tokyo) 1995, 118:753-759.
-
(1995)
J. Biochem. (Tokyo)
, vol.118
, pp. 753-759
-
-
Endo, T.1
Nakayama, Y.2
Nakai, M.3
-
7
-
-
0032718476
-
Two distinct mechanisms drive protein translocation across the mitochondrial outer membrane in the late step of the cytochrome b(2) import pathway
-
Esaki M., Kanamori T., Nishikawa S., Endo T. Two distinct mechanisms drive protein translocation across the mitochondrial outer membrane in the late step of the cytochrome b(2) import pathway. Proc. Natl. Acad. Sci. U. S. A. 1999, 96:11770-11775.
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 11770-11775
-
-
Esaki, M.1
Kanamori, T.2
Nishikawa, S.3
Endo, T.4
-
8
-
-
0038365420
-
Targeted delivery of DNA to the mitochondrial compartment via import sequence-conjugated peptide nucleic acid
-
Flierl A., Jackson C., Cottrell B., Murdock D., Seibel P., Wallace D.C. Targeted delivery of DNA to the mitochondrial compartment via import sequence-conjugated peptide nucleic acid. Mol. Ther. 2003, 7:550-557.
-
(2003)
Mol. Ther.
, vol.7
, pp. 550-557
-
-
Flierl, A.1
Jackson, C.2
Cottrell, B.3
Murdock, D.4
Seibel, P.5
Wallace, D.C.6
-
10
-
-
84856547009
-
Mitochondrial calcium homeostasis as potential target for mitochondrial medicine
-
Giorgi C., Agnoletto C., Bononi A., Bonora M., De Marchi E., Marchi S., Missiroli S., Patergnani S., Poletti F., Rimessi A., Suski J.M., Wieckowski M.R., Pinton P. Mitochondrial calcium homeostasis as potential target for mitochondrial medicine. Mitochondrion 2012, 12:77-85.
-
(2012)
Mitochondrion
, vol.12
, pp. 77-85
-
-
Giorgi, C.1
Agnoletto, C.2
Bononi, A.3
Bonora, M.4
De Marchi, E.5
Marchi, S.6
Missiroli, S.7
Patergnani, S.8
Poletti, F.9
Rimessi, A.10
Suski, J.M.11
Wieckowski, M.R.12
Pinton, P.13
-
12
-
-
0028922431
-
A novel intermediate on the import pathway of cytochrome b2 into mitochondria: evidence for conservative sorting
-
Gruhler A., Ono H., Guiard B., Neupert W., Stuart R.A. A novel intermediate on the import pathway of cytochrome b2 into mitochondria: evidence for conservative sorting. EMBO J. 1995, 14:1349-1359.
-
(1995)
EMBO J.
, vol.14
, pp. 1349-1359
-
-
Gruhler, A.1
Ono, H.2
Guiard, B.3
Neupert, W.4
Stuart, R.A.5
-
13
-
-
0023973250
-
Cloning and sequencing of the cytoplasmic precursor to the alpha subunit of rat liver mitochondrial succinyl-CoA synthetase
-
Henning W.D., Upton C., McFadden G., Majumdar R., Bridger W.A. Cloning and sequencing of the cytoplasmic precursor to the alpha subunit of rat liver mitochondrial succinyl-CoA synthetase. Proc. Natl. Acad. Sci. U. S. A. 1988, 85:1432-1436.
-
(1988)
Proc. Natl. Acad. Sci. U. S. A.
, vol.85
, pp. 1432-1436
-
-
Henning, W.D.1
Upton, C.2
McFadden, G.3
Majumdar, R.4
Bridger, W.A.5
-
14
-
-
34447558681
-
Interaction of the mitochondria-targeted antioxidant MitoQ with phospholipid bilayers and ubiquinone oxidoreductases
-
James A.M., Sharpley M.S., Manas A.R., Frerman F.E., Hirst J., Smith R.A., Murphy M.P. Interaction of the mitochondria-targeted antioxidant MitoQ with phospholipid bilayers and ubiquinone oxidoreductases. J. Biol. Chem. 2007, 282:14708-14718.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 14708-14718
-
-
James, A.M.1
Sharpley, M.S.2
Manas, A.R.3
Frerman, F.E.4
Hirst, J.5
Smith, R.A.6
Murphy, M.P.7
-
15
-
-
77949324031
-
Cell-targeting and cell-penetrating peptides for delivery of therapeutic and imaging agents
-
Juliano R.L., Alam R., Dixit V., Kang H.M. Cell-targeting and cell-penetrating peptides for delivery of therapeutic and imaging agents. Wiley Interdiscip. Rev. Nanomed. Nanobiotechnol. 2009, 1:324-335.
-
(2009)
Wiley Interdiscip. Rev. Nanomed. Nanobiotechnol.
, vol.1
, pp. 324-335
-
-
Juliano, R.L.1
Alam, R.2
Dixit, V.3
Kang, H.M.4
-
16
-
-
0036293267
-
Fluorescent lipid probes: some properties and applications (a review)
-
Maier O., Oberle V., Hoekstra D. Fluorescent lipid probes: some properties and applications (a review). Chem. Phys. Lipids 2002, 116:3-18.
-
(2002)
Chem. Phys. Lipids
, vol.116
, pp. 3-18
-
-
Maier, O.1
Oberle, V.2
Hoekstra, D.3
-
17
-
-
84858642577
-
Rational design of smart supramolecular assemblies for gene delivery: chemical challenges in the creation of artificial viruses
-
Miyata K., Nishiyama N., Kataoka K. Rational design of smart supramolecular assemblies for gene delivery: chemical challenges in the creation of artificial viruses. Chem. Soc. Rev. 2012, 41:2562-2574.
-
(2012)
Chem. Soc. Rev.
, vol.41
, pp. 2562-2574
-
-
Miyata, K.1
Nishiyama, N.2
Kataoka, K.3
-
18
-
-
78650875977
-
Receptor mediated tumor targeting: an emerging approach for cancer therapy
-
Mohanty C., Das M., Kanwar J.R., Sahoo S.K. Receptor mediated tumor targeting: an emerging approach for cancer therapy. Curr. Drug Dev. 2011, 8:45-58.
-
(2011)
Curr. Drug Dev.
, vol.8
, pp. 45-58
-
-
Mohanty, C.1
Das, M.2
Kanwar, J.R.3
Sahoo, S.K.4
-
19
-
-
34548240181
-
Delivery of drugs and macromolecules to mitochondria
-
Mukhopadhyay A., Weiner H. Delivery of drugs and macromolecules to mitochondria. Adv. Drug Deliv. Rev. 2007, 59:729-738.
-
(2007)
Adv. Drug Deliv. Rev.
, vol.59
, pp. 729-738
-
-
Mukhopadhyay, A.1
Weiner, H.2
-
20
-
-
22144447455
-
Design and development of polymers for gene delivery
-
Pack D.W., Hoffman A.S., Pun S., Stayton P.S. Design and development of polymers for gene delivery. Nat. Rev. Drug Discov. 2005, 4:581-593.
-
(2005)
Nat. Rev. Drug Discov.
, vol.4
, pp. 581-593
-
-
Pack, D.W.1
Hoffman, A.S.2
Pun, S.3
Stayton, P.S.4
-
21
-
-
57649210205
-
Mitochondrial DNA mutations in disease, aging, and neurodegeneration
-
Reeve A.K., Krishnan K.J., Turnbull D. Mitochondrial DNA mutations in disease, aging, and neurodegeneration. Ann. N. Y. Acad. Sci. 2008, 1147:21-29.
-
(2008)
Ann. N. Y. Acad. Sci.
, vol.1147
, pp. 21-29
-
-
Reeve, A.K.1
Krishnan, K.J.2
Turnbull, D.3
-
22
-
-
33745410626
-
Mitochondrial disease
-
Schapira A.H. Mitochondrial disease. Lancet 2006, 368:70-82.
-
(2006)
Lancet
, vol.368
, pp. 70-82
-
-
Schapira, A.H.1
-
23
-
-
0029774146
-
The protein import system of mitochondria
-
Schatz G. The protein import system of mitochondria. J. Biol. Chem. 1996, 271:31763-31766.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 31763-31766
-
-
Schatz, G.1
-
24
-
-
0019874707
-
Use of resonance energy transfer to monitor membrane fusion
-
Struck D.K., Hoekstra D., Pagano R.E. Use of resonance energy transfer to monitor membrane fusion. Biochemistry 1981, 20:4093-4099.
-
(1981)
Biochemistry
, vol.20
, pp. 4093-4099
-
-
Struck, D.K.1
Hoekstra, D.2
Pagano, R.E.3
-
25
-
-
0036194529
-
Mitochondria as a pharmacological target
-
Szewczyk A., Wojtczak L. Mitochondria as a pharmacological target. Pharmacol. Rev. 2002, 54:101-127.
-
(2002)
Pharmacol. Rev.
, vol.54
, pp. 101-127
-
-
Szewczyk, A.1
Wojtczak, L.2
-
26
-
-
23644433329
-
The mitochondrial genome in human adaptive radiation and disease: on the road to therapeutics and performance enhancement
-
Wallace D.C. The mitochondrial genome in human adaptive radiation and disease: on the road to therapeutics and performance enhancement. Gene 2005, 354:169-180.
-
(2005)
Gene
, vol.354
, pp. 169-180
-
-
Wallace, D.C.1
-
27
-
-
84255193135
-
Design of multifunctional non-viral gene vectors to overcome physiological barriers: dilemmas and strategies
-
Wang T., Upponi J.R., Torchilin V.P. Design of multifunctional non-viral gene vectors to overcome physiological barriers: dilemmas and strategies. Int. J. Pharm. 2012, 427:3-20.
-
(2012)
Int. J. Pharm.
, vol.427
, pp. 3-20
-
-
Wang, T.1
Upponi, J.R.2
Torchilin, V.P.3
-
28
-
-
24744454824
-
Mitochondrial targeting of selective electron scavengers: synthesis and biological analysis of hemigramicidin-TEMPO conjugates
-
Wipf P., Xiao J., Jiang J., Belikova N.A., Tyurin V.A., Fink M.P., Kagan V.E. Mitochondrial targeting of selective electron scavengers: synthesis and biological analysis of hemigramicidin-TEMPO conjugates. J. Am. Chem. Soc. 2005, 127:12460-12461.
-
(2005)
J. Am. Chem. Soc.
, vol.127
, pp. 12460-12461
-
-
Wipf, P.1
Xiao, J.2
Jiang, J.3
Belikova, N.A.4
Tyurin, V.A.5
Fink, M.P.6
Kagan, V.E.7
-
29
-
-
84860743683
-
Multifunctional envelope-type nano device (MEND) for organelle targeting via a stepwise membrane fusion process
-
Yamada Y., Akita H., Harashima H. Multifunctional envelope-type nano device (MEND) for organelle targeting via a stepwise membrane fusion process. Methods Enzymol. 2012, 509:301-326.
-
(2012)
Methods Enzymol.
, vol.509
, pp. 301-326
-
-
Yamada, Y.1
Akita, H.2
Harashima, H.3
-
30
-
-
38349036163
-
MITO-Porter: a liposome-based carrier system for delivery of macromolecules into mitochondria via membrane fusion
-
Yamada Y., Akita H., Kamiya H., Kogure K., Yamamoto T., Shinohara Y., Yamashita K., Kobayashi H., Kikuchi H., Harashima H. MITO-Porter: a liposome-based carrier system for delivery of macromolecules into mitochondria via membrane fusion. Biochim. Biophys. Acta 2008, 1778:423-432.
-
(2008)
Biochim. Biophys. Acta
, vol.1778
, pp. 423-432
-
-
Yamada, Y.1
Akita, H.2
Kamiya, H.3
Kogure, K.4
Yamamoto, T.5
Shinohara, Y.6
Yamashita, K.7
Kobayashi, H.8
Kikuchi, H.9
Harashima, H.10
-
31
-
-
33847618832
-
Mitochondrial drug delivery and mitochondrial disease therapy - an approach to liposome-based delivery targeted to mitochondria
-
Yamada Y., Akita H., Kogure K., Kamiya H., Harashima H. Mitochondrial drug delivery and mitochondrial disease therapy - an approach to liposome-based delivery targeted to mitochondria. Mitochondrion 2007, 7:63-71.
-
(2007)
Mitochondrion
, vol.7
, pp. 63-71
-
-
Yamada, Y.1
Akita, H.2
Kogure, K.3
Kamiya, H.4
Harashima, H.5
-
32
-
-
79961023252
-
Dual function MITO-Porter, a nano carrier integrating both efficient cytoplasmic delivery and mitochondrial macromolecule delivery
-
Yamada Y., Furukawa R., Yasuzaki Y., Harashima H. Dual function MITO-Porter, a nano carrier integrating both efficient cytoplasmic delivery and mitochondrial macromolecule delivery. Mol. Ther. 2011, 19:1449-1456.
-
(2011)
Mol. Ther.
, vol.19
, pp. 1449-1456
-
-
Yamada, Y.1
Furukawa, R.2
Yasuzaki, Y.3
Harashima, H.4
-
33
-
-
51249109260
-
Mitochondrial drug delivery systems for macromolecule and their therapeutic application to mitochondrial diseases
-
Yamada Y., Harashima H. Mitochondrial drug delivery systems for macromolecule and their therapeutic application to mitochondrial diseases. Adv. Drug Deliv. Rev. 2008, 60:1439-1462.
-
(2008)
Adv. Drug Deliv. Rev.
, vol.60
, pp. 1439-1462
-
-
Yamada, Y.1
Harashima, H.2
-
34
-
-
83555164614
-
Delivery of bioactive molecules to the mitochondrial genome using a membrane-fusing, liposome-based carrier, DF-MITO-Porter
-
Yamada Y., Harashima H. Delivery of bioactive molecules to the mitochondrial genome using a membrane-fusing, liposome-based carrier, DF-MITO-Porter. Biomaterials 2012, 33:1589-1595.
-
(2012)
Biomaterials
, vol.33
, pp. 1589-1595
-
-
Yamada, Y.1
Harashima, H.2
-
35
-
-
77955480347
-
Mitochondrial matrix delivery using MITO-Porter, a liposome-based carrier that specifies fusion with mitochondrial membranes
-
Yasuzaki Y., Yamada Y., Harashima H. Mitochondrial matrix delivery using MITO-Porter, a liposome-based carrier that specifies fusion with mitochondrial membranes. Biochem. Biophys. Res. Commun. 2010, 397:181-186.
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.397
, pp. 181-186
-
-
Yasuzaki, Y.1
Yamada, Y.2
Harashima, H.3
-
36
-
-
79851514312
-
Newly developed strategies for multifunctional mitochondria-targeted agents in cancer therapy
-
Zhang E., Zhang C., Su Y., Cheng T., Shi C. Newly developed strategies for multifunctional mitochondria-targeted agents in cancer therapy. Drug Discov. Today 2011, 16:140-146.
-
(2011)
Drug Discov. Today
, vol.16
, pp. 140-146
-
-
Zhang, E.1
Zhang, C.2
Su, Y.3
Cheng, T.4
Shi, C.5
|