Cell-permeable peptide antioxidants targeted to inner mitochondrial membrane inhibit mitochondrial swelling, oxidative cell death, and reperfusion injury

Journal of Biological Chemistry

Volumn 279, Issue 33, 2004, Pages 34682-34690

  Zhao, Kesheng ^a   Zhao, Guo Min ^a   Wu, Dunli ^a   Soong, Yi ^a   Birk, Alex V ^a   Schiller, Peter W ^b   Szeto, Hazel H ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOLOGICAL ORGANS; CELL MEMBRANES; DISSOCIATION; MECHANICAL PERMEABILITY; PIGMENTS; POLYPEPTIDES; TOXICITY;

APOPTOSIS; CELL DEATH; CELLULAR TOXICITY; REACTIVE OXYGEN SPECIES (ROS);

ANTIOXIDANTS;

2',6' DIMETHYLTYROSINE; 3 NITROPROPIONIC ACID; ANTIOXIDANT; AROMATIC AMINO ACID; CALCIUM ION; CYTOCHROME C; REACTIVE OXYGEN METABOLITE; TERT BUTYL HYDROPEROXIDE; TYROSINE DERIVATIVE; UNCLASSIFIED DRUG; 2',6'-DIMETHYLTYROSINE; 3-NITROPROPIONIC ACID; CALCIUM; CARDIOLIPIN; DRUG DERIVATIVE; HYDROGEN PEROXIDE; NITRO DERIVATIVE; OXYGEN; PEPTIDE; PROPIONIC ACID DERIVATIVE; TYROSINE;

ADENOCARCINOMA; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL DEATH; CELL LINE; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; DEPOLARIZATION; EX VIVO STUDY; HEART MUSCLE ISCHEMIA; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE; MITOCHONDRION SWELLING; MODEL; MOUSE; NEUROBLASTOMA CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN SECRETION; PROTEIN TRANSPORT; RAT; REPERFUSION INJURY; STUNNED HEART MUSCLE; ANIMAL; CELL STRAIN CACO 2; CELL SURVIVAL; CHEMISTRY; INTRACELLULAR MEMBRANE; LIVER; LIVER MITOCHONDRION; MALE; METABOLISM; MITOCHONDRION; OXIDATIVE STRESS; OXYGEN CONSUMPTION; PROTEIN MOTIF; REPERFUSION; TIME;

ANIMALIA;

AMINO ACID MOTIFS; ANIMALS; ANTIOXIDANTS; CACO-2 CELLS; CALCIUM; CARDIOLIPINS; CELL DEATH; CELL SURVIVAL; CYTOCHROMES C; HUMANS; HYDROGEN PEROXIDE; INTRACELLULAR MEMBRANES; LIVER; MALE; MICE; MITOCHONDRIA; MITOCHONDRIA, LIVER; NITRO COMPOUNDS; OXIDATIVE STRESS; OXYGEN; OXYGEN CONSUMPTION; PEPTIDES; PROPIONIC ACIDS; REACTIVE OXYGEN SPECIES; REPERFUSION; REPERFUSION INJURY; TERT-BUTYLHYDROPEROXIDE; TIME FACTORS; TYROSINE;

EID: 4544370680     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M402999200     Document Type: Article

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