MKT-077, a novel rhodacyanine dye in clinical trials, exhibits anticarcinoma activity in preclinical studies based on selective mitochondrial accumulation

Cancer Research

Volumn 56, Issue 3, 1996, Pages 538-543

  Koya, Keizo ^a   Li, Yang ^a   Wang, Hong ^a   Ukai, Toshinao ^b   Tatsuta, Noriaki ^b   Kawakami, Masayuki ^b   Shishido, Tadao ^b   Chen, Lan Bo ^a,c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b FUJIFILM CORPORATION   (Japan)

^c DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 ETHYL 2 [[3 ETHYL 5 (3 METHYL 2 BENZOTHIAZOLINYLIDENE)] 4 OXO 2 THIAZOLIDINYLIDENEMETHYL]PYRIDINIUM CHLORIDE; 1 ETHYL 2 [[3 ETHYL 5 (3 METHYLBENZOTHIAZOLIN 2 YLIDENE) 4 OXOTHIAZOLIDIN 2 YLIDENE]METHYL]PYRIDINIUM CHLORIDE; ANTINEOPLASTIC AGENT; CISPLATIN; CYANINE DYE; DOXORUBICIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BLADDER CARCINOMA; BREAST CARCINOMA; CANCER CELL CULTURE; CANCER SURVIVAL; CELLULAR DISTRIBUTION; COLON CARCINOMA; CONTROLLED STUDY; DRUG SOLUBILITY; DRUG STABILITY; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; INTRAVENOUS DRUG ADMINISTRATION; MALE; MELANOMA; MITOCHONDRIAL MEMBRANE; MOUSE; NONHUMAN; NUDE MOUSE; PANCREAS CARCINOMA; PRIORITY JOURNAL;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL DIVISION; CELL LINE; CERCOPITHECUS AETHIOPS; CISPLATIN; DOXORUBICIN; DRUG SCREENING ASSAYS, ANTITUMOR; ETHANOL; FEMALE; FLOW CYTOMETRY; HUMANS; KIDNEY; MALE; MICE; MICE, NUDE; MICROSCOPY, CONFOCAL; MICROSCOPY, VIDEO; MITOCHONDRIA; NEOPLASM TRANSPLANTATION; NEOPLASMS; PYRIDINES; SOLUBILITY; THIAZOLES; TUMOR CELLS, CULTURED;

EID: 0030064081     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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