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Volumn 6, Issue NOV, 2015, Pages

The timing of T cell priming and cycling

Author keywords

Cell cycle; Clonal selection; Differentiation; Expansion; Primary immune response; T cells

Indexed keywords

CD103 ANTIGEN; CD11B ANTIGEN; CD24 ANTIGEN; CYCLIN D3; CYCLIN DEPENDENT KINASE 5; CYCLIN DEPENDENT KINASE 6; CYCLIN DEPENDENT KINASE INHIBITOR 1B; FC RECEPTOR; INTERFERON CONSENSUS SEQUENCE BINDING PROTEIN; INTERFERON REGULATORY FACTOR 4; INTERLEUKIN 2; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PROTEIN KINASE ZAP 70; STAT5 PROTEIN; T LYMPHOCYTE RECEPTOR;

EID: 84949545957     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2015.00563     Document Type: Review
Times cited : (76)

References (185)
  • 1
    • 0001152394 scopus 로고
    • Allergy and immunology
    • Talmage DW. Allergy and immunology. Annu Rev Med (1957) 8:239-56. doi: 10.1146/annurev.me.08.020157.001323.
    • (1957) Annu Rev Med , vol.8 , pp. 239-256
    • Talmage, D.W.1
  • 2
    • 0000590741 scopus 로고
    • Genes and antibodies
    • Lederberg J. Genes and antibodies. Science (1959) 129:1649-53. doi:10.1126/science.129.3364.1649.
    • (1959) Science , vol.129 , pp. 1649-1653
    • Lederberg, J.1
  • 3
    • 0002225186 scopus 로고
    • A modification of Jerne's theory of antibody production using the concept of clonal selection
    • Burnet FM. A modification of Jerne's theory of antibody production using the concept of clonal selection. Aust J Sci (1957) 20:67-9.
    • (1957) Aust J Sci , vol.20 , pp. 67-69
    • Burnet, F.M.1
  • 4
    • 0000952544 scopus 로고
    • The fate of parental strain small lymphocytes in F1 hybrid rats
    • Gowans JL. The fate of parental strain small lymphocytes in F1 hybrid rats. Ann N Y Acad Sci (1962) 99:432-55. doi:10.1111/j.1749-6632.1962.tb45326.x.
    • (1962) Ann N Y Acad Sci , vol.99 , pp. 432-455
    • Gowans, J.L.1
  • 5
    • 73849181433 scopus 로고
    • Transformation of adult allogeneic small lymphocytes after transfusion into newborn rats
    • Porter KA, Cooper EH. Transformation of adult allogeneic small lymphocytes after transfusion into newborn rats. J Exp Med (1962) 115:997-1008. doi:10.1084/jem.115.5.997.
    • (1962) J Exp Med , vol.115 , pp. 997-1008
    • Porter, K.A.1    Cooper, E.H.2
  • 6
    • 36949079491 scopus 로고
    • Antigen-dependent stimulation of synthesis of deoxyribonucleic acid in spleen cells from immunized rabbits
    • Dutton RW, Pearce JD. Antigen-dependent stimulation of synthesis of deoxyribonucleic acid in spleen cells from immunized rabbits. Nature (1962) 194:93-4. doi:10.1038/194093a0.
    • (1962) Nature , vol.194 , pp. 93-94
    • Dutton, R.W.1    Pearce, J.D.2
  • 7
    • 0014031210 scopus 로고
    • One-way stimulation in mixed leukocyte cultures
    • Bach FH, Voynow NK. One-way stimulation in mixed leukocyte cultures. Science (1966) 153:545-7. doi:10.1126/science.153.3735.545.
    • (1966) Science , vol.153 , pp. 545-547
    • Bach, F.H.1    Voynow, N.K.2
  • 8
    • 0021849733 scopus 로고
    • Stimulation of the T3-T cell receptor complex induces a membrane-potential-sensitive calcium influx
    • Oettgen HC, Terhorst C, Cantley LC, RosoffPM. Stimulation of the T3-T cell receptor complex induces a membrane-potential-sensitive calcium influx. Cell (1985) 40:583-90. doi:10.1016/0092-8674(85)90206-5.
    • (1985) Cell , vol.40 , pp. 583-590
    • Oettgen, H.C.1    Terhorst, C.2    Cantley, L.C.3    Rosoff, P.M.4
  • 9
    • 0021958592 scopus 로고
    • Early steps of lymphocyte activation bypassed by synergy between calcium ionophores and phorbol ester
    • Truneh A, Albert F, Golstein P, Schmitt-Verhulst AM. Early steps of lymphocyte activation bypassed by synergy between calcium ionophores and phorbol ester. Nature (1985) 313:318-20. doi:10.1038/313318a0.
    • (1985) Nature , vol.313 , pp. 318-320
    • Truneh, A.1    Albert, F.2    Golstein, P.3    Schmitt-Verhulst, A.M.4
  • 10
    • 0021245601 scopus 로고
    • The role of T3 surface molecules in the activation of human T cells: a two-stimulus requirement for IL 2 production reflects events occurring at a pre-translational level
    • Weiss A, Wiskocil RL, Stobo JD. The role of T3 surface molecules in the activation of human T cells: a two-stimulus requirement for IL 2 production reflects events occurring at a pre-translational level. J Immunol (1984) 133:123-8.
    • (1984) J Immunol , vol.133 , pp. 123-128
    • Weiss, A.1    Wiskocil, R.L.2    Stobo, J.D.3
  • 11
    • 1842631103 scopus 로고    scopus 로고
    • Jurkat T cells and development of the T-cell receptor signalling paradigm
    • Abraham RT, Weiss A. Jurkat T cells and development of the T-cell receptor signalling paradigm. Nat Rev Immunol (2004) 4:301-8. doi:10.1038/nri1330.
    • (2004) Nat Rev Immunol , vol.4 , pp. 301-308
    • Abraham, R.T.1    Weiss, A.2
  • 12
    • 0028466130 scopus 로고
    • Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo
    • Kearney ER, Pape KA, Loh DY, Jenkins MK. Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo. Immunity (1994) 1:327-39. doi:10.1016/1074-7613(94)90084-1.
    • (1994) Immunity , vol.1 , pp. 327-339
    • Kearney, E.R.1    Pape, K.A.2    Loh, D.Y.3    Jenkins, M.K.4
  • 13
    • 0028262128 scopus 로고
    • Determination of lymphocyte division by flow cytometry
    • Lyons AB, Parish CR. Determination of lymphocyte division by flow cytometry. J Immunol Methods (1994) 171:131-7. doi:10.1016/0022-1759(94)90236-4.
    • (1994) J Immunol Methods , vol.171 , pp. 131-137
    • Lyons, A.B.1    Parish, C.R.2
  • 14
    • 0032007065 scopus 로고    scopus 로고
    • Massive expansion of antigen-specific CD8+ T cells during an acute virus infection
    • Butz EA, Bevan MJ. Massive expansion of antigen-specific CD8+ T cells during an acute virus infection. Immunity (1998) 8:167-75. doi:10.1016/S1074-7613(00)80469-0.
    • (1998) Immunity , vol.8 , pp. 167-175
    • Butz, E.A.1    Bevan, M.J.2
  • 15
    • 0032005477 scopus 로고    scopus 로고
    • Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection
    • Murali-Krishna K, Altman JD, Suresh M, Sourdive DJ, Zajac AJ, Miller JD, et al. Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection. Immunity (1998) 8:177-87. doi:10.1016/S1074-7613(00)80470-7.
    • (1998) Immunity , vol.8 , pp. 177-187
    • Murali-Krishna, K.1    Altman, J.D.2    Suresh, M.3    Sourdive, D.J.4    Zajac, A.J.5    Miller, J.D.6
  • 16
    • 84880434526 scopus 로고    scopus 로고
    • The interdisciplinary science of T-cell recognition
    • Huppa JB, Davis MM. The interdisciplinary science of T-cell recognition. Adv Immunol (2013) 119:1-50. doi:10.1016/B978-0-12-407707-2.00001-1.
    • (2013) Adv Immunol , vol.119 , pp. 1-50
    • Huppa, J.B.1    Davis, M.M.2
  • 17
    • 84927653551 scopus 로고    scopus 로고
    • Early T cell activation: integrating biochemical, structural, and biophysical cues
    • Malissen B, Bongrand P. Early T cell activation: integrating biochemical, structural, and biophysical cues. Annu Rev Immunol (2015) 33:539-61. doi:10.1146/annurev-immunol-032414-112158.
    • (2015) Annu Rev Immunol , vol.33 , pp. 539-561
    • Malissen, B.1    Bongrand, P.2
  • 18
    • 84906241799 scopus 로고    scopus 로고
    • Insights into the initiation of TCR signaling
    • Chakraborty AK, Weiss A. Insights into the initiation of TCR signaling. Nat Immunol (2014) 15:798-807. doi:10.1038/ni.2940.
    • (2014) Nat Immunol , vol.15 , pp. 798-807
    • Chakraborty, A.K.1    Weiss, A.2
  • 19
    • 84867896903 scopus 로고    scopus 로고
    • + T cell differentiation
    • + T cell differentiation. Nat Rev Immunol (2012) 12:749-61. doi:10.1038/nri3307.
    • (2012) Nat Rev Immunol , vol.12 , pp. 749-761
    • Kaech, S.M.1    Cui, W.2
  • 20
    • 84922260071 scopus 로고    scopus 로고
    • The role of T cell receptor signaling thresholds in guiding T cell fate decisions
    • Zikherman J, Au-Yeung B. The role of T cell receptor signaling thresholds in guiding T cell fate decisions. Curr Opin Immunol (2015) 33:43-8. doi:10.1016/j.coi.2015.01.012.
    • (2015) Curr Opin Immunol , vol.33 , pp. 43-48
    • Zikherman, J.1    Au-Yeung, B.2
  • 21
    • 84863599237 scopus 로고    scopus 로고
    • TCR signaling requirements for activating T cells and for generating memory
    • Zehn D, King C, Bevan MJ, Palmer E. TCR signaling requirements for activating T cells and for generating memory. Cell Mol Life Sci (2012) 69:1565-75. doi:10.1007/s00018-012-0965-x.
    • (2012) Cell Mol Life Sci , vol.69 , pp. 1565-1575
    • Zehn, D.1    King, C.2    Bevan, M.J.3    Palmer, E.4
  • 22
    • 77649220954 scopus 로고    scopus 로고
    • + T cells
    • + T cells. Science (2010) 327:1098-102. doi:10.1126/science.1178334.
    • (2010) Science , vol.327 , pp. 1098-1102
    • O'Shea, J.J.1    Paul, W.E.2
  • 23
    • 85027948869 scopus 로고    scopus 로고
    • Distinct TCR signaling pathways drive proliferation and cytokine production in T cells
    • Guy CS, Vignali KM, Temirov J, Bettini ML, Overacre AE, Smeltzer M, et al. Distinct TCR signaling pathways drive proliferation and cytokine production in T cells. Nat Immunol (2013) 14:262-70. doi:10.1038/ni.2538.
    • (2013) Nat Immunol , vol.14 , pp. 262-270
    • Guy, C.S.1    Vignali, K.M.2    Temirov, J.3    Bettini, M.L.4    Overacre, A.E.5    Smeltzer, M.6
  • 25
    • 42649101626 scopus 로고    scopus 로고
    • Choreography of cell motility and interaction dynamics imaged by two-photon microscopy in lymphoid organs
    • Cahalan MD, Parker I. Choreography of cell motility and interaction dynamics imaged by two-photon microscopy in lymphoid organs. Annu Rev Immunol (2008) 26:585-626. doi:10.1146/annurev.immunol.24.021605.090620.
    • (2008) Annu Rev Immunol , vol.26 , pp. 585-626
    • Cahalan, M.D.1    Parker, I.2
  • 26
    • 84888141725 scopus 로고    scopus 로고
    • Visualizing how T cells collect activation signals in vivo
    • Moreau HD, Bousso P. Visualizing how T cells collect activation signals in vivo. Curr Opin Immunol (2014) 26:56-62. doi:10.1016/j.coi.2013.10.013.
    • (2014) Curr Opin Immunol , vol.26 , pp. 56-62
    • Moreau, H.D.1    Bousso, P.2
  • 27
    • 84930211068 scopus 로고    scopus 로고
    • Spatiotemporal basis of innate and adaptive immunity in secondary lymphoid tissue
    • Qi H, Kastenmüller W, Germain RN. Spatiotemporal basis of innate and adaptive immunity in secondary lymphoid tissue. Annu Rev Cell Dev Biol (2014) 30:141-67. doi:10.1146/annurev-cellbio-100913-013254.
    • (2014) Annu Rev Cell Dev Biol , vol.30 , pp. 141-167
    • Qi, H.1    Kastenmüller, W.2    Germain, R.N.3
  • 29
    • 84868608267 scopus 로고    scopus 로고
    • How many dendritic cells are required to initiate a T-cell response?
    • Celli S, Day M, Muller AJ, Molina-Paris C, Lythe G, Bousso P. How many dendritic cells are required to initiate a T-cell response? Blood (2012) 120:3945-8. doi:10.1182/blood-2012-01-408260.
    • (2012) Blood , vol.120 , pp. 3945-3948
    • Celli, S.1    Day, M.2    Muller, A.J.3    Molina-Paris, C.4    Lythe, G.5    Bousso, P.6
  • 30
    • 0037501371 scopus 로고    scopus 로고
    • + T cell priming by dendritic cells in intact lymph nodes
    • + T cell priming by dendritic cells in intact lymph nodes. Nat Immunol (2003) 4:579-85. doi:10.1038/ni928.
    • (2003) Nat Immunol , vol.4 , pp. 579-585
    • Bousso, P.1    Robey, E.2
  • 31
    • 0030888235 scopus 로고    scopus 로고
    • Antigen receptor engagement delivers a stop signal to migrating T lymphocytes
    • Dustin ML, Bromley SK, Kan Z, Peterson DA, Unanue ER. Antigen receptor engagement delivers a stop signal to migrating T lymphocytes. Proc Natl Acad Sci U S A (1997) 94:3909-13. doi:10.1073/pnas.94.8.3909.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 3909-3913
    • Dustin, M.L.1    Bromley, S.K.2    Kan, Z.3    Peterson, D.A.4    Unanue, E.R.5
  • 32
    • 0347717903 scopus 로고    scopus 로고
    • T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases
    • Mempel TR, Henrickson SE, von Andrian UH. T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases. Nature (2004) 427:154-9. doi:10.1038/nature02238.
    • (2004) Nature , vol.427 , pp. 154-159
    • Mempel, T.R.1    Henrickson, S.E.2    von Andrian, U.H.3
  • 33
    • 0742323358 scopus 로고    scopus 로고
    • T cell repertoire scanning is promoted by dynamic dendritic cell behavior and random T cell motility in the lymph node
    • Miller MJ, Hejazi AS, Wei SH, Cahalan MD, Parker I. T cell repertoire scanning is promoted by dynamic dendritic cell behavior and random T cell motility in the lymph node. Proc Natl Acad Sci U S A (2004) 101:998-1003. doi:10.1073/pnas.0306407101.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 998-1003
    • Miller, M.J.1    Hejazi, A.S.2    Wei, S.H.3    Cahalan, M.D.4    Parker, I.5
  • 34
    • 3142696783 scopus 로고    scopus 로고
    • The mitogen-induced increase in T cell size involves PKC and NFAT activation of Rel/NF-kappaB-dependent c-myc expression
    • Grumont R, Lock P, Mollinari M, Shannon FM, Moore A, Gerondakis S. The mitogen-induced increase in T cell size involves PKC and NFAT activation of Rel/NF-kappaB-dependent c-myc expression. Immunity (2004) 21:19-30. doi:10.1016/j.immuni.2004.06.004.
    • (2004) Immunity , vol.21 , pp. 19-30
    • Grumont, R.1    Lock, P.2    Mollinari, M.3    Shannon, F.M.4    Moore, A.5    Gerondakis, S.6
  • 37
    • 84875494365 scopus 로고    scopus 로고
    • Metabolic regulation of T lymphocytes
    • MacIver NJ, Michalek RD, Rathmell JC. Metabolic regulation of T lymphocytes. Annu Rev Immunol (2013) 31:259-83. doi:10.1146/annurev-immunol-032712-095956.
    • (2013) Annu Rev Immunol , vol.31 , pp. 259-283
    • MacIver, N.J.1    Michalek, R.D.2    Rathmell, J.C.3
  • 40
    • 84947591002 scopus 로고    scopus 로고
    • T cell metabolism drives immunity
    • Buck MD, O'Sullivan D, Pearce EL. T cell metabolism drives immunity. J Exp Med (2015) 212:1345-60. doi:10.1084/jem.20151159.
    • (2015) J Exp Med , vol.212 , pp. 1345-1360
    • Buck, M.D.1    O'Sullivan, D.2    Pearce, E.L.3
  • 41
    • 39449094869 scopus 로고    scopus 로고
    • T cell sensing of antigen dose governs interactive behavior with dendritic cells and sets a threshold for T cell activation
    • Henrickson SE, Mempel TR, Mazo IB, Liu B, Artyomov MN, Zheng H, et al. T cell sensing of antigen dose governs interactive behavior with dendritic cells and sets a threshold for T cell activation. Nat Immunol (2008) 9:282-91. doi:10.1038/ni1559.
    • (2008) Nat Immunol , vol.9 , pp. 282-291
    • Henrickson, S.E.1    Mempel, T.R.2    Mazo, I.B.3    Liu, B.4    Artyomov, M.N.5    Zheng, H.6
  • 42
    • 0033666324 scopus 로고    scopus 로고
    • Antigen presentation in extracellular matrix: interactions of T cells with dendritic cells are dynamic, short lived, and sequential
    • Gunzer M, Schafer A, Borgmann S, Grabbe S, Zanker KS, Brocker EB, et al. Antigen presentation in extracellular matrix: interactions of T cells with dendritic cells are dynamic, short lived, and sequential. Immunity (2000) 13:323-32. doi:10.1016/S1074-7613(00)00032-7.
    • (2000) Immunity , vol.13 , pp. 323-332
    • Gunzer, M.1    Schafer, A.2    Borgmann, S.3    Grabbe, S.4    Zanker, K.S.5    Brocker, E.B.6
  • 43
    • 0042847271 scopus 로고    scopus 로고
    • T lymphocyte activation by repeated immunological synapse formation and intermittent signaling
    • Faroudi M, Zaru R, Paulet P, Muller S, Valitutti S. T lymphocyte activation by repeated immunological synapse formation and intermittent signaling. J Immunol (2003) 171:1128-32. doi:10.4049/jimmunol.171.3.1128.
    • (2003) J Immunol , vol.171 , pp. 1128-1132
    • Faroudi, M.1    Zaru, R.2    Paulet, P.3    Muller, S.4    Valitutti, S.5
  • 44
    • 4644323006 scopus 로고    scopus 로고
    • A spectrum of biophysical interaction modes between T cells and different antigen-presenting cells during priming in 3-D collagen and in vivo
    • Gunzer M, Weishaupt C, Hillmer A, Basoglu Y, Friedl P, Dittmar KE, et al. A spectrum of biophysical interaction modes between T cells and different antigen-presenting cells during priming in 3-D collagen and in vivo. Blood (2004) 104:2801-9. doi:10.1182/blood-2004-03-1193.
    • (2004) Blood , vol.104 , pp. 2801-2809
    • Gunzer, M.1    Weishaupt, C.2    Hillmer, A.3    Basoglu, Y.4    Friedl, P.5    Dittmar, K.E.6
  • 45
    • 79955738613 scopus 로고    scopus 로고
    • A role for the immediate early gene product c-fos in imprinting T cells with short-term memory for signal summation
    • Clark CE, Hasan M, Bousso P. A role for the immediate early gene product c-fos in imprinting T cells with short-term memory for signal summation. PLoS One (2011) 6:e18916. doi:10.1371/journal.pone.0018916.
    • (2011) PLoS One , vol.6
    • Clark, C.E.1    Hasan, M.2    Bousso, P.3
  • 46
    • 84874273811 scopus 로고    scopus 로고
    • The transcription factor NFAT exhibits signal memory during serial T cell interactions with antigen-presenting cells
    • Marangoni F, Murooka TT, Manzo T, Kim EY, Carrizosa E, Elpek NM, et al. The transcription factor NFAT exhibits signal memory during serial T cell interactions with antigen-presenting cells. Immunity (2013) 38:237-49. doi:10.1016/j.immuni.2012.09.012.
    • (2013) Immunity , vol.38 , pp. 237-249
    • Marangoni, F.1    Murooka, T.T.2    Manzo, T.3    Kim, E.Y.4    Carrizosa, E.5    Elpek, N.M.6
  • 47
    • 0344029278 scopus 로고
    • Nature of alloreactivity. Frequency of responding cells
    • Klein J. New York, NY: Wiley-Interscience
    • Klein J. Nature of alloreactivity. Frequency of responding cells. In: Klein J. Natural History of the Major Histocompatibility Complex. New York, NY: Wiley-Interscience (1986). p. 417-21.
    • (1986) Natural History of the Major Histocompatibility Complex , pp. 417-421
    • Klein, J.1
  • 49
    • 0035863825 scopus 로고    scopus 로고
    • Quantifying the frequency of alloreactive T cells in vivo: new answers to an old question
    • Suchin EJ, Langmuir PB, Palmer E, Sayegh MH, Wells AD, Turka LA. Quantifying the frequency of alloreactive T cells in vivo: new answers to an old question. J Immunol (2001) 166:973-81. doi:10.4049/jimmunol.166.2.973.
    • (2001) J Immunol , vol.166 , pp. 973-981
    • Suchin, E.J.1    Langmuir, P.B.2    Palmer, E.3    Sayegh, M.H.4    Wells, A.D.5    Turka, L.A.6
  • 52
    • 84949567457 scopus 로고    scopus 로고
    • Lower affinity T cells are critical components and active participants of the immune response
    • Martinez RJ, Evavold BD. Lower affinity T cells are critical components and active participants of the immune response. Front Immunol (2015) 6:468. doi:10.3389/fimmu.2015.00468.
    • (2015) Front Immunol , vol.6 , pp. 468
    • Martinez, R.J.1    Evavold, B.D.2
  • 53
    • 84919681010 scopus 로고    scopus 로고
    • Antibody stabilization of peptide-MHC multimers reveals functional T cells bearing extremely low-affinity TCRs
    • Tungatt K, Bianchi V, Crowther MD, Powell WE, Schauenburg AJ, Trimby A, et al. Antibody stabilization of peptide-MHC multimers reveals functional T cells bearing extremely low-affinity TCRs. J Immunol (2015) 194:463-74. doi:10.4049/jimmunol.1401785.
    • (2015) J Immunol , vol.194 , pp. 463-474
    • Tungatt, K.1    Bianchi, V.2    Crowther, M.D.3    Powell, W.E.4    Schauenburg, A.J.5    Trimby, A.6
  • 54
    • 84860346184 scopus 로고    scopus 로고
    • The role of naive T cell precursor frequency and recruitment in dictating immune response magnitude
    • Jenkins MK, Moon JJ. The role of naive T cell precursor frequency and recruitment in dictating immune response magnitude. J Immunol (2012) 188:4135-40. doi:10.4049/jimmunol.1102661.
    • (2012) J Immunol , vol.188 , pp. 4135-4140
    • Jenkins, M.K.1    Moon, J.J.2
  • 55
    • 84921278229 scopus 로고    scopus 로고
    • T cell receptor cross-reactivity between similar foreign and self peptides influences naive cell population size and autoimmunity
    • Nelson RW, Beisang D, Tubo NJ, Dileepan T, Wiesner DL, Nielsen K, et al. T cell receptor cross-reactivity between similar foreign and self peptides influences naive cell population size and autoimmunity. Immunity (2015) 42:95-107. doi:10.1016/j.immuni.2014.12.022.
    • (2015) Immunity , vol.42 , pp. 95-107
    • Nelson, R.W.1    Beisang, D.2    Tubo, N.J.3    Dileepan, T.4    Wiesner, D.L.5    Nielsen, K.6
  • 60
    • 77953195865 scopus 로고    scopus 로고
    • Primary CTL response magnitude in mice is determined by the extent of naive T cell recruitment and subsequent clonal expansion
    • La Gruta NL, Rothwell WT, Cukalac T, Swan NG, Valkenburg SA, Kedzierska K, et al. Primary CTL response magnitude in mice is determined by the extent of naive T cell recruitment and subsequent clonal expansion. J Clin Invest (2010) 120:1885-94. doi:10.1172/JCI41538.
    • (2010) J Clin Invest , vol.120 , pp. 1885-1894
    • La Gruta, N.L.1    Rothwell, W.T.2    Cukalac, T.3    Swan, N.G.4    Valkenburg, S.A.5    Kedzierska, K.6
  • 61
    • 84916603649 scopus 로고    scopus 로고
    • The control of the specificity of CD4 T cell responses: thresholds, breakpoints, and ceilings
    • Sant AJ, Chaves FA, Leddon SA, Tung J. The control of the specificity of CD4 T cell responses: thresholds, breakpoints, and ceilings. Front Immunol (2013) 4:340. doi:10.3389/fimmu.2013.00340.
    • (2013) Front Immunol , vol.4 , pp. 340
    • Sant, A.J.1    Chaves, F.A.2    Leddon, S.A.3    Tung, J.4
  • 62
    • 84920683669 scopus 로고    scopus 로고
    • Determinants of immunodominance for CD4 T cells
    • Kim A, Sadegh-Nasseri S. Determinants of immunodominance for CD4 T cells. Curr Opin Immunol (2015) 34:9-15. doi:10.1016/j.coi.2014.12.005.
    • (2015) Curr Opin Immunol , vol.34 , pp. 9-15
    • Kim, A.1    Sadegh-Nasseri, S.2
  • 63
    • 84874244135 scopus 로고    scopus 로고
    • T cell-positive selection uses self-ligand binding strength to optimize repertoire recognition of foreign antigens
    • Mandl JN, Monteiro JP, Vrisekoop N, Germain RN. T cell-positive selection uses self-ligand binding strength to optimize repertoire recognition of foreign antigens. Immunity (2013) 38:263-74. doi:10.1016/j.immuni.2012.09.011.
    • (2013) Immunity , vol.38 , pp. 263-274
    • Mandl, J.N.1    Monteiro, J.P.2    Vrisekoop, N.3    Germain, R.N.4
  • 64
    • 84894447120 scopus 로고    scopus 로고
    • Intrinsic CD4+ T cell sensitivity and response to a pathogen are set and sustained by avidity for thymic and peripheral complexes of self peptide and MHC
    • Persaud SP, Parker CR, Lo WL, Weber KS, Allen PM. Intrinsic CD4+ T cell sensitivity and response to a pathogen are set and sustained by avidity for thymic and peripheral complexes of self peptide and MHC. Nat Immunol (2014) 15:266-74. doi:10.1038/ni.2822.
    • (2014) Nat Immunol , vol.15 , pp. 266-274
    • Persaud, S.P.1    Parker, C.R.2    Lo, W.L.3    Weber, K.S.4    Allen, P.M.5
  • 65
    • 84924979971 scopus 로고    scopus 로고
    • The TCR's sensitivity to self peptide-MHC dictates the ability of naive CD8+ T cells to respond to foreign antigens
    • Fulton RB, Hamilton SE, Xing Y, Best JA, Goldrath AW, Hogquist KA, et al. The TCR's sensitivity to self peptide-MHC dictates the ability of naive CD8+ T cells to respond to foreign antigens. Nat Immunol (2015) 16:107-17. doi:10.1038/ni.3043.
    • (2015) Nat Immunol , vol.16 , pp. 107-117
    • Fulton, R.B.1    Hamilton, S.E.2    Xing, Y.3    Best, J.A.4    Goldrath, A.W.5    Hogquist, K.A.6
  • 70
    • 0036118394 scopus 로고    scopus 로고
    • Recombinant vaccinia virus-induced T-cell immunity: quantitation of the response to the virus vector and the foreign epitope
    • Harrington LE, van der Most RG, Whitton JL, Ahmed R. Recombinant vaccinia virus-induced T-cell immunity: quantitation of the response to the virus vector and the foreign epitope. J Virol (2002) 76:3329-37. doi:10.1128/JVI.76.7.3329-3337.2002.
    • (2002) J Virol , vol.76 , pp. 3329-3337
    • Harrington, L.E.1    van der Most, R.G.2    Whitton, J.L.3    Ahmed, R.4
  • 72
    • 0037083612 scopus 로고    scopus 로고
    • CD4 and CD8 T cells are intrinsically different in their proliferative responses
    • Foulds KE, Zenewicz LA, Shedlock DJ, Jiang J, Troy AE, Shen H. CD4 and CD8 T cells are intrinsically different in their proliferative responses. J Immunol (2002) 168:1528-32. doi:10.4049/jimmunol.168.4.1528.
    • (2002) J Immunol , vol.168 , pp. 1528-1532
    • Foulds, K.E.1    Zenewicz, L.A.2    Shedlock, D.J.3    Jiang, J.4    Troy, A.E.5    Shen, H.6
  • 73
    • 0041381363 scopus 로고    scopus 로고
    • + effector and memory T cell generation
    • + effector and memory T cell generation. Nat Immunol (2003) 4:835-42. doi:10.1038/ni969.
    • (2003) Nat Immunol , vol.4 , pp. 835-842
    • Seder, R.A.1    Ahmed, R.2
  • 74
    • 1842373718 scopus 로고    scopus 로고
    • Duration of TCR stimulation determines costimulatory requirement of T cells
    • Kündig TM, Shahinian A, Kawai K, Mittrücker HW, Sebzda E, Bachmann MF, et al. Duration of TCR stimulation determines costimulatory requirement of T cells. Immunity (1996) 5:41-52. doi:10.1016/S1074-7613(00)80308-8.
    • (1996) Immunity , vol.5 , pp. 41-52
    • Kündig, T.M.1    Shahinian, A.2    Kawai, K.3    Mittrücker, H.W.4    Sebzda, E.5    Bachmann, M.F.6
  • 75
    • 0033662432 scopus 로고    scopus 로고
    • Functional flexibility in T cells: independent regulation of CD4+ T cell proliferation and effector function in vivo
    • Laouar Y, Crispe IN. Functional flexibility in T cells: independent regulation of CD4+ T cell proliferation and effector function in vivo. Immunity (2000) 13:291-301. doi:10.1016/S1074-7613(00)00029-7.
    • (2000) Immunity , vol.13 , pp. 291-301
    • Laouar, Y.1    Crispe, I.N.2
  • 76
    • 84888358815 scopus 로고    scopus 로고
    • The power of dilution: using adoptive transfer to study TCR transgenic T cells
    • Sprent J. The power of dilution: using adoptive transfer to study TCR transgenic T cells. J Immunol (2013) 191:5325-6. doi:10.4049/jimmunol.1302679.
    • (2013) J Immunol , vol.191 , pp. 5325-5326
    • Sprent, J.1
  • 77
    • 0031884839 scopus 로고    scopus 로고
    • The duration of antigenic stimulation determines the fate of naive and effector T cells
    • Iezzi G, Karjalainen K, Lanzavecchia A. The duration of antigenic stimulation determines the fate of naive and effector T cells. Immunity (1998) 8:89-95. doi:10.1016/S1074-7613(00)80461-6.
    • (1998) Immunity , vol.8 , pp. 89-95
    • Iezzi, G.1    Karjalainen, K.2    Lanzavecchia, A.3
  • 78
    • 0035348175 scopus 로고    scopus 로고
    • + T cell differentiation: initial antigen encounter triggers a developmental program in naive cells
    • + T cell differentiation: initial antigen encounter triggers a developmental program in naive cells. Nat Immunol (2001) 2:415-22. doi:10.1038/87720.
    • (2001) Nat Immunol , vol.2 , pp. 415-422
    • Kaech, S.M.1    Ahmed, R.2
  • 79
    • 0035348246 scopus 로고    scopus 로고
    • Naive CTLs require a single brief period of antigenic stimulation for clonal expansion and differentiation
    • van Stipdonk MJ, Lemmens EE, Schoenberger SP. Naive CTLs require a single brief period of antigenic stimulation for clonal expansion and differentiation. Nat Immunol (2001) 2:423-9. doi:10.1038/87730.
    • (2001) Nat Immunol , vol.2 , pp. 423-429
    • van Stipdonk, M.J.1    Lemmens, E.E.2    Schoenberger, S.P.3
  • 80
    • 0035873191 scopus 로고    scopus 로고
    • Antigen-independent CD8 T cell proliferation
    • Wong P, Pamer EG. Antigen-independent CD8 T cell proliferation. J Immunol (2001) 166:5864-8. doi:10.4049/jimmunol.166.10.5864.
    • (2001) J Immunol , vol.166 , pp. 5864-5868
    • Wong, P.1    Pamer, E.G.2
  • 82
    • 50549103806 scopus 로고    scopus 로고
    • Development of CTL memory despite arrested clonal expansion
    • van Stipdonk MJ, Sluijter M, Han WG, Offringa R. Development of CTL memory despite arrested clonal expansion. Eur J Immunol (2008) 38:1839-46. doi:10.1002/eji.200737974.
    • (2008) Eur J Immunol , vol.38 , pp. 1839-1846
    • van Stipdonk, M.J.1    Sluijter, M.2    Han, W.G.3    Offringa, R.4
  • 83
    • 33746238541 scopus 로고    scopus 로고
    • Duration of CTL activation regulates IL-2 production required for autonomous clonal expansion
    • Spierings DC, Lemmens EE, Grewal K, Schoenberger SP, Green DR. Duration of CTL activation regulates IL-2 production required for autonomous clonal expansion. Eur J Immunol (2006) 36:1707-17. doi:10.1002/eji.200635929.
    • (2006) Eur J Immunol , vol.36 , pp. 1707-1717
    • Spierings, D.C.1    Lemmens, E.E.2    Grewal, K.3    Schoenberger, S.P.4    Green, D.R.5
  • 84
    • 41949097030 scopus 로고    scopus 로고
    • The biology of interleukin-2
    • Malek TR. The biology of interleukin-2. Annu Rev Immunol (2008) 26:453-79. doi:10.1146/annurev.immunol.26.021607.090357.
    • (2008) Annu Rev Immunol , vol.26 , pp. 453-479
    • Malek, T.R.1
  • 85
    • 0842343444 scopus 로고    scopus 로고
    • Disparate in vitro and in vivo requirements for IL-2 during antigen-independent CD8 T cell expansion
    • Wong P, Pamer EG. Disparate in vitro and in vivo requirements for IL-2 during antigen-independent CD8 T cell expansion. J Immunol (2004) 172:2171-6. doi:10.4049/jimmunol.172.4.2171.
    • (2004) J Immunol , vol.172 , pp. 2171-2176
    • Wong, P.1    Pamer, E.G.2
  • 86
    • 33947667310 scopus 로고    scopus 로고
    • + T regulatory cells
    • + T regulatory cells. J Immunol (2007) 178:4062-71. doi:10.4049/jimmunol.178.7.4062.
    • (2007) J Immunol , vol.178 , pp. 4062-4071
    • Bayer, A.L.1    Yu, A.2    Malek, T.R.3
  • 87
    • 27544446622 scopus 로고    scopus 로고
    • Development and function of agonist-induced CD25+Foxp3+ regulatory T cells in the absence of interleukin 2 signaling
    • D'Cruz LM, Klein L. Development and function of agonist-induced CD25+Foxp3+ regulatory T cells in the absence of interleukin 2 signaling. Nat Immunol (2005) 6:1152-9. doi:10.1038/ni1264.
    • (2005) Nat Immunol , vol.6 , pp. 1152-1159
    • D'Cruz, L.M.1    Klein, L.2
  • 88
    • 27544481941 scopus 로고    scopus 로고
    • A function for interleukin 2 in Foxp3-expressing regulatory T cells
    • Fontenot JD, Rasmussen JP, Gavin MA, Rudensky AY. A function for interleukin 2 in Foxp3-expressing regulatory T cells. Nat Immunol (2005) 6:1142-51. doi:10.1038/ni1263.
    • (2005) Nat Immunol , vol.6 , pp. 1142-1151
    • Fontenot, J.D.1    Rasmussen, J.P.2    Gavin, M.A.3    Rudensky, A.Y.4
  • 89
    • 68949120834 scopus 로고    scopus 로고
    • The initial phase of an immune response functions to activate regulatory T cells
    • O'Gorman WE, Dooms H, Thorne SH, Kuswanto WF, Simonds EF, Krutzik PO, et al. The initial phase of an immune response functions to activate regulatory T cells. J Immunol (2009) 183:332-9. doi:10.4049/jimmunol.0900691.
    • (2009) J Immunol , vol.183 , pp. 332-339
    • O'Gorman, W.E.1    Dooms, H.2    Thorne, S.H.3    Kuswanto, W.F.4    Simonds, E.F.5    Krutzik, P.O.6
  • 93
    • 84914690072 scopus 로고    scopus 로고
    • Antigen affinity, costimulation, and cytokine inputs sum linearly to amplify T cell expansion
    • Marchingo JM, Kan A, Sutherland RM, Duffy KR, Wellard CJ, Belz GT, et al. Antigen affinity, costimulation, and cytokine inputs sum linearly to amplify T cell expansion. Science (2014) 346:1123-7. doi:10.1126/science.1260044.
    • (2014) Science , vol.346 , pp. 1123-1127
    • Marchingo, J.M.1    Kan, A.2    Sutherland, R.M.3    Duffy, K.R.4    Wellard, C.J.5    Belz, G.T.6
  • 94
    • 84892534048 scopus 로고    scopus 로고
    • IL-12 and type I interferon prolong the division of activated CD8 T cells by maintaining high-affinity IL-2 signaling in vivo
    • Starbeck-Miller GR, Xue HH, Harty JT. IL-12 and type I interferon prolong the division of activated CD8 T cells by maintaining high-affinity IL-2 signaling in vivo. J Exp Med (2014) 211:105-20. doi:10.1084/jem.20130901.
    • (2014) J Exp Med , vol.211 , pp. 105-120
    • Starbeck-Miller, G.R.1    Xue, H.H.2    Harty, J.T.3
  • 95
    • 0034671979 scopus 로고    scopus 로고
    • Early programming of T cell populations responding to bacterial infection
    • Mercado R, Vijh S, Allen SE, Kerksiek K, Pilip IM, Pamer EG. Early programming of T cell populations responding to bacterial infection. J Immunol (2000) 165:6833-9. doi:10.4049/jimmunol.165.12.6833.
    • (2000) J Immunol , vol.165 , pp. 6833-6839
    • Mercado, R.1    Vijh, S.2    Allen, S.E.3    Kerksiek, K.4    Pilip, I.M.5    Pamer, E.G.6
  • 96
    • 6344269987 scopus 로고    scopus 로고
    • Duration of infection and antigen display have minimal influence on the kinetics of the CD4+ T cell response to Listeria monocytogenes infection
    • Corbin GA, Harty JT. Duration of infection and antigen display have minimal influence on the kinetics of the CD4+ T cell response to Listeria monocytogenes infection. J Immunol (2004) 173:5679-87. doi:10.4049/jimmunol.173.9.5679.
    • (2004) J Immunol , vol.173 , pp. 5679-5687
    • Corbin, G.A.1    Harty, J.T.2
  • 97
    • 9144224291 scopus 로고    scopus 로고
    • Shortening the infectious period does not alter expansion of CD8 T cells but diminishes their capacity to differentiate into memory cells
    • Williams MA, Bevan MJ. Shortening the infectious period does not alter expansion of CD8 T cells but diminishes their capacity to differentiate into memory cells. J Immunol (2004) 173:6694-702. doi:10.4049/jimmunol.173.11.6694.
    • (2004) J Immunol , vol.173 , pp. 6694-6702
    • Williams, M.A.1    Bevan, M.J.2
  • 98
    • 0032033695 scopus 로고    scopus 로고
    • Coordinate regulation of complex T cell populations responding to bacterial infection
    • Busch DH, Pilip IM, Vijh S, Pamer EG. Coordinate regulation of complex T cell populations responding to bacterial infection. Immunity (1998) 8:353-62. doi:10.1016/S1074-7613(00)80540-3.
    • (1998) Immunity , vol.8 , pp. 353-362
    • Busch, D.H.1    Pilip, I.M.2    Vijh, S.3    Pamer, E.G.4
  • 100
    • 0035344684 scopus 로고    scopus 로고
    • The CD8 response on autopilot
    • Bevan MJ, Fink PJ. The CD8 response on autopilot. Nat Immunol (2001) 2:381-2. doi:10.1038/87676.
    • (2001) Nat Immunol , vol.2 , pp. 381-382
    • Bevan, M.J.1    Fink, P.J.2
  • 101
    • 0036302171 scopus 로고    scopus 로고
    • + T cell responses: it's all downhill after their prime
    • + T cell responses: it's all downhill after their prime. Nat Immunol (2002) 3:601-2. doi:10.1038/ni0702-601.
    • (2002) Nat Immunol , vol.3 , pp. 601-602
    • Blattman, J.N.1    Cheng, L.E.2    Greenberg, P.D.3
  • 102
    • 1542321204 scopus 로고    scopus 로고
    • The role of programming in memory T-cell development
    • Masopust D, Kaech SM, Wherry EJ, Ahmed R. The role of programming in memory T-cell development. Curr Opin Immunol (2004) 16:217-25. doi:10.1016/j.coi.2004.02.005.
    • (2004) Curr Opin Immunol , vol.16 , pp. 217-225
    • Masopust, D.1    Kaech, S.M.2    Wherry, E.J.3    Ahmed, R.4
  • 103
    • 77951692771 scopus 로고    scopus 로고
    • Plasticity in programming of effector and memory CD8 T-cell formation
    • Arens R, Schoenberger SP. Plasticity in programming of effector and memory CD8 T-cell formation. Immunol Rev (2010) 235:190-205. doi:10.1111/j.0105-2896.2010.00899.x.
    • (2010) Immunol Rev , vol.235 , pp. 190-205
    • Arens, R.1    Schoenberger, S.P.2
  • 104
    • 0242579946 scopus 로고    scopus 로고
    • CD8 T cell clonal expansion and development of effector function require prolonged exposure to antigen, costimulation, and signal 3 cytokine
    • Curtsinger JM, Johnson CM, Mescher MF. CD8 T cell clonal expansion and development of effector function require prolonged exposure to antigen, costimulation, and signal 3 cytokine. J Immunol (2003) 171:5165-71. doi:10.4049/jimmunol.171.10.5165.
    • (2003) J Immunol , vol.171 , pp. 5165-5171
    • Curtsinger, J.M.1    Johnson, C.M.2    Mescher, M.F.3
  • 105
    • 0038445969 scopus 로고    scopus 로고
    • Innate immunity together with duration of antigen persistence regulate effector T cell induction
    • Storni T, Ruedl C, Renner WA, Bachmann MF. Innate immunity together with duration of antigen persistence regulate effector T cell induction. J Immunol (2003) 171:795-801. doi:10.4049/jimmunol.171.2.795.
    • (2003) J Immunol , vol.171 , pp. 795-801
    • Storni, T.1    Ruedl, C.2    Renner, W.A.3    Bachmann, M.F.4
  • 106
    • 65249102388 scopus 로고    scopus 로고
    • + memory T cells and protective capacities in Listeria monocytogenes-infected mice upon rechallenge
    • + memory T cells and protective capacities in Listeria monocytogenes-infected mice upon rechallenge. J Immunol (2009) 182:4590-600. doi:10.4049/jimmunol.0801125.
    • (2009) J Immunol , vol.182 , pp. 4590-4600
    • Tseng, K.E.1    Chung, C.Y.2    H'Ng, W.S.3    Wang, S.L.4
  • 109
    • 33645848936 scopus 로고    scopus 로고
    • + T cells that enter the draining lymph nodes after antigen injection participate in the primary response and become central-memory cells
    • + T cells that enter the draining lymph nodes after antigen injection participate in the primary response and become central-memory cells. J Exp Med (2006) 203:1045-54. doi:10.1084/jem.20051954.
    • (2006) J Exp Med , vol.203 , pp. 1045-1054
    • Catron, D.M.1    Rusch, L.K.2    Hataye, J.3    Itano, A.A.4    Jenkins, M.K.5
  • 110
    • 38449095428 scopus 로고    scopus 로고
    • Extent of stimulation controls the formation of memory CD8 T cells
    • Quigley M, Huang X, Yang Y. Extent of stimulation controls the formation of memory CD8 T cells. J Immunol (2007) 179:5768-77. doi:10.4049/jimmunol.179.9.5768.
    • (2007) J Immunol , vol.179 , pp. 5768-5777
    • Quigley, M.1    Huang, X.2    Yang, Y.3
  • 112
    • 58149229634 scopus 로고    scopus 로고
    • A novel CD11c. DTR transgenic mouse for depletion of dendritic cells reveals their requirement for homeostatic proliferation of natural killer cells
    • Hochweller K, Striegler J, Hämmerling GJ, Garbi N. A novel CD11c. DTR transgenic mouse for depletion of dendritic cells reveals their requirement for homeostatic proliferation of natural killer cells. Eur J Immunol (2008) 38:2776-83. doi:10.1002/eji.200838659.
    • (2008) Eur J Immunol , vol.38 , pp. 2776-2783
    • Hochweller, K.1    Striegler, J.2    Hämmerling, G.J.3    Garbi, N.4
  • 113
    • 84928685251 scopus 로고    scopus 로고
    • + macrophages are sufficient for priming of CTLs with specificities left out by cross-priming dendritic cells
    • + macrophages are sufficient for priming of CTLs with specificities left out by cross-priming dendritic cells. Proc Natl Acad Sci U S A (2015) 112:5461-6. doi:10.1073/pnas.1423356112.
    • (2015) Proc Natl Acad Sci U S A , vol.112 , pp. 5461-5466
    • Bernhard, C.A.1    Ried, C.2    Kochanek, S.3    Brocker, T.4
  • 114
    • 81855203183 scopus 로고    scopus 로고
    • Dendritic cells control lymphocyte entry to lymph nodes through high endothelial venules
    • Moussion C, Girard JP. Dendritic cells control lymphocyte entry to lymph nodes through high endothelial venules. Nature (2011) 479:542-6. doi:10.1038/nature10540.
    • (2011) Nature , vol.479 , pp. 542-546
    • Moussion, C.1    Girard, J.P.2
  • 116
    • 33750823918 scopus 로고    scopus 로고
    • Differential requirement for Lck during primary and memory CD8+ T cell responses
    • Tewari K, Walent J, Svaren J, Zamoyska R, Suresh M. Differential requirement for Lck during primary and memory CD8+ T cell responses. Proc Natl Acad Sci U S A (2006) 103:16388-93. doi:10.1073/pnas.0602565103.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 16388-16393
    • Tewari, K.1    Walent, J.2    Svaren, J.3    Zamoyska, R.4    Suresh, M.5
  • 117
    • 40449088958 scopus 로고    scopus 로고
    • CD8 T cell expansion and memory differentiation are facilitated by simultaneous and sustained exposure to antigenic and inflammatory milieu
    • Shaulov A, Murali-Krishna K. CD8 T cell expansion and memory differentiation are facilitated by simultaneous and sustained exposure to antigenic and inflammatory milieu. J Immunol (2008) 180:1131-8. doi:10.4049/jimmunol.180.2.1131.
    • (2008) J Immunol , vol.180 , pp. 1131-1138
    • Shaulov, A.1    Murali-Krishna, K.2
  • 118
    • 80052665758 scopus 로고    scopus 로고
    • Duration of antigen availability influences the expansion and memory differentiation of T cells
    • Blair DA, Turner DL, Bose TO, Pham QM, Bouchard KR, Williams KJ, et al. Duration of antigen availability influences the expansion and memory differentiation of T cells. J Immunol (2011) 187:2310-21. doi:10.4049/jimmunol.1100363.
    • (2011) J Immunol , vol.187 , pp. 2310-2321
    • Blair, D.A.1    Turner, D.L.2    Bose, T.O.3    Pham, Q.M.4    Bouchard, K.R.5    Williams, K.J.6
  • 120
    • 34250797888 scopus 로고    scopus 로고
    • + T cells in the draining lymph nodes in response to pulmonary virus infection
    • + T cells in the draining lymph nodes in response to pulmonary virus infection. J Immunol (2007) 179:391-9. doi:10.4049/jimmunol.179.1.391.
    • (2007) J Immunol , vol.179 , pp. 391-399
    • Yoon, H.1    Legge, K.L.2    Sung, S.S.3    Braciale, T.J.4
  • 121
    • 70449715724 scopus 로고    scopus 로고
    • Contribution of lung-resident T cell proliferation to the overall magnitude of the antigen-specific CD8 T cell response in the lungs following murine influenza virus infection
    • McGill J, Legge KL. Contribution of lung-resident T cell proliferation to the overall magnitude of the antigen-specific CD8 T cell response in the lungs following murine influenza virus infection. J Immunol (2009) 183:4177-81. doi:10.4049/jimmunol.0901109.
    • (2009) J Immunol , vol.183 , pp. 4177-4181
    • McGill, J.1    Legge, K.L.2
  • 122
    • 46949088340 scopus 로고    scopus 로고
    • Protective influenza-specific CD8 T cell responses require interactions with dendritic cells in the lungs
    • McGill J, Van Rooijen N, Legge KL. Protective influenza-specific CD8 T cell responses require interactions with dendritic cells in the lungs. J Exp Med (2008) 205:1635-46. doi:10.1084/jem.20080314.
    • (2008) J Exp Med , vol.205 , pp. 1635-1646
    • McGill, J.1    Van Rooijen, N.2    Legge, K.L.3
  • 124
    • 84905087931 scopus 로고    scopus 로고
    • Prolonged antigen presentation by immune complex-binding dendritic cells programs the proliferative capacity of memory CD8 T cells
    • León B, Ballesteros-Tato A, Randall TD, Lund FE. Prolonged antigen presentation by immune complex-binding dendritic cells programs the proliferative capacity of memory CD8 T cells. J Exp Med (2014) 211:1637-55. doi:10.1084/jem.20131692.
    • (2014) J Exp Med , vol.211 , pp. 1637-1655
    • León, B.1    Ballesteros-Tato, A.2    Randall, T.D.3    Lund, F.E.4
  • 125
    • 79955727320 scopus 로고    scopus 로고
    • Migration of cytotoxic lymphocytes in cell cycle permits local MHC I-dependent control of division at sites of viral infection
    • Kang SS, Herz J, Kim JV, Nayak D, Stewart-Hutchinson P, Dustin ML, et al. Migration of cytotoxic lymphocytes in cell cycle permits local MHC I-dependent control of division at sites of viral infection. J Exp Med (2011) 208:747-59. doi:10.1084/jem.20101295.
    • (2011) J Exp Med , vol.208 , pp. 747-759
    • Kang, S.S.1    Herz, J.2    Kim, J.V.3    Nayak, D.4    Stewart-Hutchinson, P.5    Dustin, M.L.6
  • 126
    • 0037120052 scopus 로고    scopus 로고
    • + T cells is amplified by prolonged T cell antigen receptor triggering
    • + T cells is amplified by prolonged T cell antigen receptor triggering. J Exp Med (2002) 196:793-803. doi:10.1084/jem.20020158.
    • (2002) J Exp Med , vol.196 , pp. 793-803
    • Schrum, A.G.1    Turka, L.A.2
  • 128
    • 14744300036 scopus 로고    scopus 로고
    • Distinct temporal programming of naive CD4+ T cells for cell division versus TCR-dependent death susceptibility by antigen-presenting macrophages
    • Schrum AG, Palmer E, Turka LA. Distinct temporal programming of naive CD4+ T cells for cell division versus TCR-dependent death susceptibility by antigen-presenting macrophages. Eur J Immunol (2005) 35:449-59. doi:10.1002/eji.200425635.
    • (2005) Eur J Immunol , vol.35 , pp. 449-459
    • Schrum, A.G.1    Palmer, E.2    Turka, L.A.3
  • 129
    • 70149086749 scopus 로고    scopus 로고
    • + T cell recall responses is controlled by the duration of the secondary stimulus
    • + T cell recall responses is controlled by the duration of the secondary stimulus. J Immunol (2009) 183:2382-9. doi:10.4049/jimmunol.0900319.
    • (2009) J Immunol , vol.183 , pp. 2382-2389
    • Ravkov, E.V.1    Williams, M.A.2
  • 131
    • 27744502556 scopus 로고    scopus 로고
    • CD4 T cells integrate signals delivered during successive DC encounters in vivo
    • Celli S, Garcia Z, Bousso P. CD4 T cells integrate signals delivered during successive DC encounters in vivo. J Exp Med (2005) 202:1271-8. doi:10.1084/jem.20051018.
    • (2005) J Exp Med , vol.202 , pp. 1271-1278
    • Celli, S.1    Garcia, Z.2    Bousso, P.3
  • 133
    • 24344435571 scopus 로고    scopus 로고
    • Unexpected prolonged presentation of influenza antigens promotes CD4 T cell memory generation
    • Jelley-Gibbs DM, Brown DM, Dibble JP, Haynes L, Eaton SM, Swain SL. Unexpected prolonged presentation of influenza antigens promotes CD4 T cell memory generation. J Exp Med (2005) 202:697-706. doi:10.1084/jem.20050227.
    • (2005) J Exp Med , vol.202 , pp. 697-706
    • Jelley-Gibbs, D.M.1    Brown, D.M.2    Dibble, J.P.3    Haynes, L.4    Eaton, S.M.5    Swain, S.L.6
  • 135
    • 35448944386 scopus 로고    scopus 로고
    • Increased competition for antigen during priming negatively impacts the generation of memory CD4 T cells
    • Blair DA, Lefrancois L. Increased competition for antigen during priming negatively impacts the generation of memory CD4 T cells. Proc Natl Acad Sci U S A (2007) 104:15045-50. doi:10.1073/pnas.0703767104.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 15045-15050
    • Blair, D.A.1    Lefrancois, L.2
  • 136
    • 45549083554 scopus 로고    scopus 로고
    • Increasing the CD4+ T cell precursor frequency leads to competition for IFN-? thereby degrading memory cell quantity and quality
    • Whitmire JK, Benning N, Eam B, Whitton JL. Increasing the CD4+ T cell precursor frequency leads to competition for IFN-? thereby degrading memory cell quantity and quality. J Immunol (2008) 180:6777-85. doi:10.4049/jimmunol.180.10.6777.
    • (2008) J Immunol , vol.180 , pp. 6777-6785
    • Whitmire, J.K.1    Benning, N.2    Eam, B.3    Whitton, J.L.4
  • 137
    • 66649110510 scopus 로고    scopus 로고
    • Abortive activation of CD4 T cell responses during competitive priming in vivo
    • Weaver JM, Chaves FA, Sant AJ. Abortive activation of CD4 T cell responses during competitive priming in vivo. Proc Natl Acad Sci U S A (2009) 106:8647-52. doi:10.1073/pnas.0811584106.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 8647-8652
    • Weaver, J.M.1    Chaves, F.A.2    Sant, A.J.3
  • 140
    • 0034327174 scopus 로고    scopus 로고
    • Two distinct stages in the transition from naive CD4 T cells to effectors, early antigen-dependent and late cytokine-driven expansion and differentiation
    • Jelley-Gibbs DM, Lepak NM, Yen M, Swain SL. Two distinct stages in the transition from naive CD4 T cells to effectors, early antigen-dependent and late cytokine-driven expansion and differentiation. J Immunol (2000) 165:5017-26. doi:10.4049/jimmunol.165.9.5017.
    • (2000) J Immunol , vol.165 , pp. 5017-5026
    • Jelley-Gibbs, D.M.1    Lepak, N.M.2    Yen, M.3    Swain, S.L.4
  • 141
    • 0037083665 scopus 로고    scopus 로고
    • Repeated antigen exposure is necessary for the differentiation, but not the initial proliferation, of naive CD4+ T cells
    • BajénoffM, Wurtz O, Guerder S. Repeated antigen exposure is necessary for the differentiation, but not the initial proliferation, of naive CD4+ T cells. J Immunol (2002) 168:1723-9. doi:10.4049/jimmunol.168.4.1723.
    • (2002) J Immunol , vol.168 , pp. 1723-1729
    • Bajénoff, M.1    Wurtz, O.2    Guerder, S.3
  • 142
    • 0037083613 scopus 로고    scopus 로고
    • Continued antigen stimulation is not required during CD4+ T cell clonal expansion
    • Lee WT, Pasos G, Cecchini L, Mittler JN. Continued antigen stimulation is not required during CD4+ T cell clonal expansion. J Immunol (2002) 168:1682-9. doi:10.4049/jimmunol.168.4.1682.
    • (2002) J Immunol , vol.168 , pp. 1682-1689
    • Lee, W.T.1    Pasos, G.2    Cecchini, L.3    Mittler, J.N.4
  • 143
    • 17144422129 scopus 로고    scopus 로고
    • Repeated stimulation of CD4 effector T cells can limit their protective function
    • Jelley-Gibbs DM, Dibble JP, Filipson S, Haynes L, Kemp RA, Swain SL. Repeated stimulation of CD4 effector T cells can limit their protective function. J Exp Med (2005) 201:1101-12. doi:10.1084/jem.20041852.
    • (2005) J Exp Med , vol.201 , pp. 1101-1112
    • Jelley-Gibbs, D.M.1    Dibble, J.P.2    Filipson, S.3    Haynes, L.4    Kemp, R.A.5    Swain, S.L.6
  • 145
    • 84938397867 scopus 로고    scopus 로고
    • T-cell exhaustion, co-stimulation and clinical outcome in autoimmunity and infection
    • McKinney EF, Lee JC, Jayne DRW, Lyons PA, Smith KGC. T-cell exhaustion, co-stimulation and clinical outcome in autoimmunity and infection. Nature (2015) 523:612-6. doi:10.1038/nature14468.
    • (2015) Nature , vol.523 , pp. 612-616
    • McKinney, E.F.1    Lee, J.C.2    Jayne, D.R.W.3    Lyons, P.A.4    Smith, K.G.C.5
  • 146
    • 33750837708 scopus 로고    scopus 로고
    • Coreceptor signal strength regulates positive selection but does not determine CD4/CD8 lineage choice in a physiologic in vivo model
    • Erman B, Alag AS, Dahle O, van Laethem F, Sarafova SD, Guinter TI, et al. Coreceptor signal strength regulates positive selection but does not determine CD4/CD8 lineage choice in a physiologic in vivo model. J Immunol (2006) 177:6613-25. doi:10.4049/jimmunol.177.10.6613.
    • (2006) J Immunol , vol.177 , pp. 6613-6625
    • Erman, B.1    Alag, A.S.2    Dahle, O.3    van Laethem, F.4    Sarafova, S.D.5    Guinter, T.I.6
  • 147
    • 84884248064 scopus 로고    scopus 로고
    • Lck availability during thymic selection determines the recognition specificity of the T cell repertoire
    • Van Laethem F, Tikhonova AN, Pobezinsky LA, Tai X, Kimura MY, Le Saout C, et al. Lck availability during thymic selection determines the recognition specificity of the T cell repertoire. Cell (2013) 154:1326-41. doi:10.1016/j.cell.2013.08.009.
    • (2013) Cell , vol.154 , pp. 1326-1341
    • Van Laethem, F.1    Tikhonova, A.N.2    Pobezinsky, L.A.3    Tai, X.4    Kimura, M.Y.5    Le Saout, C.6
  • 149
    • 1542377327 scopus 로고    scopus 로고
    • Duration of TCR signaling controls CD4-CD8 lineage differentiation in vivo
    • Liu X, Bosselut R. Duration of TCR signaling controls CD4-CD8 lineage differentiation in vivo. Nat Immunol (2004) 5:280-8. doi:10.1038/ni1040.
    • (2004) Nat Immunol , vol.5 , pp. 280-288
    • Liu, X.1    Bosselut, R.2
  • 150
    • 77953629991 scopus 로고    scopus 로고
    • Regulation of Zap70 expression during thymocyte development enables temporal separation of CD4 and CD8 repertoire selection at different signaling thresholds
    • Saini M, Sinclair C, Marshall D, Tolaini M, Sakaguchi S, Seddon B. Regulation of Zap70 expression during thymocyte development enables temporal separation of CD4 and CD8 repertoire selection at different signaling thresholds. Sci Signal (2010) 3:ra23. doi:10.1126/scisignal.2000702.
    • (2010) Sci Signal , vol.3
    • Saini, M.1    Sinclair, C.2    Marshall, D.3    Tolaini, M.4    Sakaguchi, S.5    Seddon, B.6
  • 151
    • 84875493408 scopus 로고    scopus 로고
    • Memory T cell subsets, migration patterns, and tissue residence
    • Mueller SN, Gebhardt T, Carbone FR, Heath WR. Memory T cell subsets, migration patterns, and tissue residence. Annu Rev Immunol (2013) 31:137-61. doi:10.1146/annurev-immunol-032712-095954.
    • (2013) Annu Rev Immunol , vol.31 , pp. 137-161
    • Mueller, S.N.1    Gebhardt, T.2    Carbone, F.R.3    Heath, W.R.4
  • 152
    • 74549130997 scopus 로고    scopus 로고
    • T cell detection of a B-cell tropic virus infection: newly-synthesised versus mature viral proteins as antigen sources for CD4 and CD8 epitope display
    • Mackay LK, Long HM, Brooks JM, Taylor GS, Leung CS, Chen A, et al. T cell detection of a B-cell tropic virus infection: newly-synthesised versus mature viral proteins as antigen sources for CD4 and CD8 epitope display. PLoS Pathog (2009) 5:e1000699. doi:10.1371/journal.ppat.1000699.
    • (2009) PLoS Pathog , vol.5
    • Mackay, L.K.1    Long, H.M.2    Brooks, J.M.3    Taylor, G.S.4    Leung, C.S.5    Chen, A.6
  • 153
    • 0030858138 scopus 로고    scopus 로고
    • Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells
    • Cella M, Engering A, Pinet V, Pieters J, Lanzavecchia A. Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells. Nature (1997) 388:782-7. doi:10.1038/42030.
    • (1997) Nature , vol.388 , pp. 782-787
    • Cella, M.1    Engering, A.2    Pinet, V.3    Pieters, J.4    Lanzavecchia, A.5
  • 154
    • 0030869567 scopus 로고    scopus 로고
    • Developmental regulation of MHC class II transport in mouse dendritic cells
    • Pierre P, Turley SJ, Gatti E, Hull M, Meltzer J, Mirza A, et al. Developmental regulation of MHC class II transport in mouse dendritic cells. Nature (1997) 388:787-92. doi:10.1038/42039.
    • (1997) Nature , vol.388 , pp. 787-792
    • Pierre, P.1    Turley, S.J.2    Gatti, E.3    Hull, M.4    Meltzer, J.5    Mirza, A.6
  • 155
    • 33750593611 scopus 로고    scopus 로고
    • Surface expression of MHC class II in dendritic cells is controlled by regulated ubiquitination
    • Shin JS, Ebersold M, Pypaert M, Delamarre L, Hartley A, Mellman I. Surface expression of MHC class II in dendritic cells is controlled by regulated ubiquitination. Nature (2006) 444:115-8. doi:10.1038/nature05261.
    • (2006) Nature , vol.444 , pp. 115-118
    • Shin, J.S.1    Ebersold, M.2    Pypaert, M.3    Delamarre, L.4    Hartley, A.5    Mellman, I.6
  • 156
    • 33845397207 scopus 로고    scopus 로고
    • Dendritic cells regulate exposure of MHC class II at their plasma membrane by oligoubiquitination
    • van Niel G, Wubbolts R, ten Broeke T, Buschow SI, Ossendorp FA, Melief CJ, et al. Dendritic cells regulate exposure of MHC class II at their plasma membrane by oligoubiquitination. Immunity (2006) 25:885-94. doi:10.1016/j.immuni.2006.11.001.
    • (2006) Immunity , vol.25 , pp. 885-894
    • van Niel, G.1    Wubbolts, R.2    ten Broeke, T.3    Buschow, S.I.4    Ossendorp, F.A.5    Melief, C.J.6
  • 157
    • 42149179893 scopus 로고    scopus 로고
    • MHC class II stabilization at the surface of human dendritic cells is the result of maturation-dependent MARCH I down-regulation
    • De Gassart A, Camosseto V, Thibodeau J, Ceppi M, Catalan N, Pierre P, et al. MHC class II stabilization at the surface of human dendritic cells is the result of maturation-dependent MARCH I down-regulation. Proc Natl Acad Sci U S A (2008) 105:3491-6. doi:10.1073/pnas.0708874105.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 3491-3496
    • De Gassart, A.1    Camosseto, V.2    Thibodeau, J.3    Ceppi, M.4    Catalan, N.5    Pierre, P.6
  • 158
    • 84939811650 scopus 로고    scopus 로고
    • Ubiquitination by March-I prevents MHC class II recycling and promotes MHC class II turnover in antigen-presenting cells
    • Cho KJ, Walseng E, Ishido S, Roche PA. Ubiquitination by March-I prevents MHC class II recycling and promotes MHC class II turnover in antigen-presenting cells. Proc Natl Acad Sci U S A (2015) 112:10449-54. doi:10.1073/pnas.1507981112.
    • (2015) Proc Natl Acad Sci U S A , vol.112 , pp. 10449-10454
    • Cho, K.J.1    Walseng, E.2    Ishido, S.3    Roche, P.A.4
  • 160
    • 84892815323 scopus 로고    scopus 로고
    • Transcriptional programming of dendritic cells for enhanced MHC class II antigen presentation
    • Vander Lugt B, Khan AA, Hackney JA, Agrawal S, Lesch J, Zhou M, et al. Transcriptional programming of dendritic cells for enhanced MHC class II antigen presentation. Nat Immunol (2014) 15:161-7. doi:10.1038/ni.2795.
    • (2014) Nat Immunol , vol.15 , pp. 161-167
    • Vander Lugt, B.1    Khan, A.A.2    Hackney, J.A.3    Agrawal, S.4    Lesch, J.5    Zhou, M.6
  • 161
    • 84941356605 scopus 로고    scopus 로고
    • Robust anti-viral immunity requires multiple distinct T cell-dendritic cell interactions
    • EickhoffS, Brewitz A, Gerner MY, Klauschen F, Komander K, Hemmi H, et al. Robust anti-viral immunity requires multiple distinct T cell-dendritic cell interactions. Cell (2015) 162:1322-37. doi:10.1016/j.cell.2015.08.004.
    • (2015) Cell , vol.162 , pp. 1322-1337
    • Eickhoff, S.1    Brewitz, A.2    Gerner, M.Y.3    Klauschen, F.4    Komander, K.5    Hemmi, H.6
  • 163
    • 47249150250 scopus 로고    scopus 로고
    • Inhibition of ZAP-70 kinase activity via an analog-sensitive allele blocks T cell receptor and CD28 superagonist signaling
    • Levin SE, Zhang C, Kadlecek TA, Shokat KM, Weiss A. Inhibition of ZAP-70 kinase activity via an analog-sensitive allele blocks T cell receptor and CD28 superagonist signaling. J Biol Chem (2008) 283:15419-30. doi:10.1074/jbc. M709000200.
    • (2008) J Biol Chem , vol.283 , pp. 15419-15430
    • Levin, S.E.1    Zhang, C.2    Kadlecek, T.A.3    Shokat, K.M.4    Weiss, A.5
  • 164
    • 78449287872 scopus 로고    scopus 로고
    • A genetically selective inhibitor demonstrates a function for the kinase Zap70 in regulatory T cells independent of its catalytic activity
    • 1085-U95
    • Au-Yeung BB, Levin SE, Zhang C, Hsu LY, Cheng DA, Killeen N, et al. A genetically selective inhibitor demonstrates a function for the kinase Zap70 in regulatory T cells independent of its catalytic activity. Nat Immunol (2010) 11:1085-U95. doi:10.1038/ni.1955.
    • (2010) Nat Immunol , vol.11
    • Au-Yeung, B.B.1    Levin, S.E.2    Zhang, C.3    Hsu, L.Y.4    Cheng, D.A.5    Killeen, N.6
  • 165
    • 84865721122 scopus 로고    scopus 로고
    • Endogenous antigen tunes the responsiveness of naive B cells but not T cells
    • 160-U85
    • Zikherman J, Parameswaran R, Weiss A. Endogenous antigen tunes the responsiveness of naive B cells but not T cells. Nature (2012) 489:160-U85. doi:10.1038/nature11311.
    • (2012) Nature , vol.489
    • Zikherman, J.1    Parameswaran, R.2    Weiss, A.3
  • 167
    • 1542724587 scopus 로고    scopus 로고
    • Cytometry of the cell cycle: cycling through history
    • Darzynkiewicz Z, Crissman H, Jacobberger JW. Cytometry of the cell cycle: cycling through history. Cytometry (2004) 58:21-32. doi:10.1002/cyto.a.20003.
    • (2004) Cytometry , vol.58 , pp. 21-32
    • Darzynkiewicz, Z.1    Crissman, H.2    Jacobberger, J.W.3
  • 168
    • 84949234712 scopus 로고    scopus 로고
    • Assaying cell cycle status using flow cytometry
    • 28.6.1-28.6.11
    • Kim KH, Sederstrom JM. Assaying cell cycle status using flow cytometry. Curr Protoc Mol Biol (2015) 111:28.6.1-28.6.11. doi:10.1002/0471142727.mb2806s111.
    • (2015) Curr Protoc Mol Biol , vol.111
    • Kim, K.H.1    Sederstrom, J.M.2
  • 169
    • 84931437298 scopus 로고    scopus 로고
    • Initiation and termination of DNA replication during S phase in relation to cyclins D1, E and A, p21WAF1, Cdt1 and the p12 subunit of DNA polymerase d revealed in individual cells by cytometry
    • Darzynkiewicz Z, Zhao H, Zhang S, Lee MYWT, Lee EYC, Zhang Z. Initiation and termination of DNA replication during S phase in relation to cyclins D1, E and A, p21WAF1, Cdt1 and the p12 subunit of DNA polymerase d revealed in individual cells by cytometry. Oncotarget (2015) 6:11735-50. doi:10.18632/oncotarget.4149.
    • (2015) Oncotarget , vol.6 , pp. 11735-11750
    • Darzynkiewicz, Z.1    Zhao, H.2    Zhang, S.3    Lee, M.Y.W.T.4    Lee, E.Y.C.5    Zhang, Z.6
  • 170
    • 84940202961 scopus 로고    scopus 로고
    • Analysis of cell proliferation and homeostasis using EdU labeling
    • Flomerfelt FA, Gress RE. Analysis of cell proliferation and homeostasis using EdU labeling. Methods Mol Biol (2016) 1323:211-20. doi:10.1007/978-1-4939-2809-5_18.
    • (2016) Methods Mol Biol , vol.1323 , pp. 211-220
    • Flomerfelt, F.A.1    Gress, R.E.2
  • 171
    • 84901644301 scopus 로고    scopus 로고
    • Clonal selection in the germinal centre by regulated proliferation and hypermutation
    • Gitlin AD, Shulman Z, Nussenzweig MC. Clonal selection in the germinal centre by regulated proliferation and hypermutation. Nature (2014) 509:637-40. doi:10.1038/nature13300.
    • (2014) Nature , vol.509 , pp. 637-640
    • Gitlin, A.D.1    Shulman, Z.2    Nussenzweig, M.C.3
  • 172
    • 84939635025 scopus 로고    scopus 로고
    • T cell help controls the speed of the cell cycle in germinal center B cells
    • Gitlin AD, Mayer CT, Oliveira TY, Shulman Z, Jones MJ, Koren A, et al. T cell help controls the speed of the cell cycle in germinal center B cells. Science (2015) 349:643-6. doi:10.1126/science.aac4919.
    • (2015) Science , vol.349 , pp. 643-646
    • Gitlin, A.D.1    Mayer, C.T.2    Oliveira, T.Y.3    Shulman, Z.4    Jones, M.J.5    Koren, A.6
  • 173
    • 56549128268 scopus 로고    scopus 로고
    • Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair
    • Wilson A, Laurenti E, Oser G, van der Wath RC, Blanco-Bose W, Jaworski M, et al. Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair. Cell (2008) 135:1118-29. doi:10.1016/j.cell.2008.10.048.
    • (2008) Cell , vol.135 , pp. 1118-1129
    • Wilson, A.1    Laurenti, E.2    Oser, G.3    van der Wath, R.C.4    Blanco-Bose, W.5    Jaworski, M.6
  • 174
    • 38849199681 scopus 로고    scopus 로고
    • Visualizing spatiotemporal dynamics of multicellular cell-cycle progression
    • Sakaue-Sawano A, Kurokawa H, Morimura T, Hanyu A, Hama H, Osawa H, et al. Visualizing spatiotemporal dynamics of multicellular cell-cycle progression. Cell (2008) 132:487-98. doi:10.1016/j.cell.2007.12.033.
    • (2008) Cell , vol.132 , pp. 487-498
    • Sakaue-Sawano, A.1    Kurokawa, H.2    Morimura, T.3    Hanyu, A.4    Hama, H.5    Osawa, H.6
  • 176
    • 84923914366 scopus 로고    scopus 로고
    • Real-time tracking of cell cycle progression during CD8+ effector and memory T-cell differentiation
    • Kinjyo I, Qin J, Tan SY, Wellard CJ, Mrass P, Ritchie W, et al. Real-time tracking of cell cycle progression during CD8+ effector and memory T-cell differentiation. Nat Commun (2015) 6:6301. doi:10.1038/ncomms7301.
    • (2015) Nat Commun , vol.6 , pp. 6301
    • Kinjyo, I.1    Qin, J.2    Tan, S.Y.3    Wellard, C.J.4    Mrass, P.5    Ritchie, W.6
  • 177
    • 9144229104 scopus 로고    scopus 로고
    • Requirement for cyclin D3 in lymphocyte development and T cell leukemias
    • Sicinska E, Aifantis I, Le Cam L, Swat W, Borowski C, Yu Q, et al. Requirement for cyclin D3 in lymphocyte development and T cell leukemias. Cancer Cell (2003) 4:451-61. doi:10.1016/S1535-6108(03)00301-5.
    • (2003) Cancer Cell , vol.4 , pp. 451-461
    • Sicinska, E.1    Aifantis, I.2    Le Cam, L.3    Swat, W.4    Borowski, C.5    Yu, Q.6
  • 178
    • 14844353313 scopus 로고    scopus 로고
    • Opposing roles for the cyclin-dependent kinase inhibitor p27kip1 in the control of CD4+ T cell proliferation and effector function
    • Rowell EA, Walsh MC, Wells AD. Opposing roles for the cyclin-dependent kinase inhibitor p27kip1 in the control of CD4+ T cell proliferation and effector function. J Immunol (2005) 174:3359-68. doi:10.4049/jimmunol.174.6.3359.
    • (2005) J Immunol , vol.174 , pp. 3359-3368
    • Rowell, E.A.1    Walsh, M.C.2    Wells, A.D.3
  • 180
    • 78149352604 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 5 activity is required for T cell activation and induction of experimental autoimmune encephalomyelitis
    • Pareek TK, Lam E, Zheng X, Askew D, Kulkarni AB, Chance MR, et al. Cyclin-dependent kinase 5 activity is required for T cell activation and induction of experimental autoimmune encephalomyelitis. J Exp Med (2010) 207:2507-19. doi:10.1084/jem.20100876.
    • (2010) J Exp Med , vol.207 , pp. 2507-2519
    • Pareek, T.K.1    Lam, E.2    Zheng, X.3    Askew, D.4    Kulkarni, A.B.5    Chance, M.R.6
  • 181
    • 0346496026 scopus 로고    scopus 로고
    • High expression of active CDK6 in the cytoplasm of CD8 memory cells favors rapid division
    • Veiga-Fernandes H, Rocha B. High expression of active CDK6 in the cytoplasm of CD8 memory cells favors rapid division. Nat Immunol (2004) 5:31-7. doi:10.1038/ni1015.
    • (2004) Nat Immunol , vol.5 , pp. 31-37
    • Veiga-Fernandes, H.1    Rocha, B.2
  • 182
    • 77955346275 scopus 로고    scopus 로고
    • Antigen-specific clonal expansion and cytolytic effector function of CD8+ T lymphocytes depend on the transcription factor Bcl11b
    • Zhang S, Rozell M, Verma RK, Albu DI, Califano D, VanValkenburgh J, et al. Antigen-specific clonal expansion and cytolytic effector function of CD8+ T lymphocytes depend on the transcription factor Bcl11b. J Exp Med (2010) 207:1687-99. doi:10.1084/jem.20092136.
    • (2010) J Exp Med , vol.207 , pp. 1687-1699
    • Zhang, S.1    Rozell, M.2    Verma, R.K.3    Albu, D.I.4    Califano, D.5    VanValkenburgh, J.6
  • 183
    • 77949509908 scopus 로고    scopus 로고
    • FoxM1, a forkhead transcription factor is a master cell cycle regulator for mouse mature T cells but not double positive thymocytes
    • Xue L, Chiang L, He B, Zhao YY, Winoto A. FoxM1, a forkhead transcription factor is a master cell cycle regulator for mouse mature T cells but not double positive thymocytes. PLoS One (2010) 5:e9229. doi:10.1371/journal.pone.0009229.
    • (2010) PLoS One , vol.5
    • Xue, L.1    Chiang, L.2    He, B.3    Zhao, Y.Y.4    Winoto, A.5
  • 184
    • 77951929029 scopus 로고    scopus 로고
    • Differential geminin requirement for proliferation of thymocytes and mature T cells
    • Karamitros D, Kotantaki P, Lygerou Z, Veiga-Fernandes H, Pachnis V, Kioussis D, et al. Differential geminin requirement for proliferation of thymocytes and mature T cells. J Immunol (2010) 184:2432-41. doi:10.4049/jimmunol.0901983.
    • (2010) J Immunol , vol.184 , pp. 2432-2441
    • Karamitros, D.1    Kotantaki, P.2    Lygerou, Z.3    Veiga-Fernandes, H.4    Pachnis, V.5    Kioussis, D.6
  • 185
    • 84902342846 scopus 로고    scopus 로고
    • CTP synthase 1 deficiency in humans reveals its central role in lymphocyte proliferation
    • Martin E, Palmic N, Sanquer S, Lenoir C, Hauck F, Mongellaz C, et al. CTP synthase 1 deficiency in humans reveals its central role in lymphocyte proliferation. Nature (2014) 510:288-92. doi:10.1038/nature13386.
    • (2014) Nature , vol.510 , pp. 288-292
    • Martin, E.1    Palmic, N.2    Sanquer, S.3    Lenoir, C.4    Hauck, F.5    Mongellaz, C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.