Duration of TCR stimulation determines costimulatory requirement of T cells

Immunity

Volumn 5, Issue 1, 1996, Pages 41-52

  Kündig, Thomas M ^a   Shahinian, Arda ^b   Kawai, Kazuhiro ^a   Mittrücker, Hans Willi ^a   Sebzda, Eric ^a   Bachmann, Martin F ^a   Mak, Tak W ^a,b   Ohashi, Pamela S ^a  

^a PRINCESS MARGARET HOSPITAL   (Canada)

^b AMGEN INSTITUTE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CD28 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; T LYMPHOCYTE RECEPTOR; VIRUS PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CLONAL ANERGY; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; CYTOTOXICITY; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; VESICULAR STOMATITIS VIRUS; VIRUS INFECTION; VIRUS VIRULENCE;

EID: 1842373718     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(00)80308-8     Document Type: Article

References (67)

1. Aichele, P., Brduscha-Riem, K., Zinkernagel, R.M., Hengartner, H., and Pircher, H.P. (1995). T cell priming versus T cell tolerance induced by synthetic peptides. J. Exp. Med. 182, 261-266.
2. Allison, J.P. (1994). CD28-B7 interactions in T-cell activation. Curr. Opin. Immunol. 6, 414-419.
3. Ando, K., Guidotti, L.G., Cerny, A., Ishikawa, T., and Chisari, F.V. (1994). CTL access to tissue antigen is restricted in vivo. J. Immunol. 153, 482-488.
4. Bachmann, M.F., and Kündig, T.M. (1994). In vitro vs. in vivo assays for the assessment of T-and B-cell function. Curr. Opin. Immunol. 6, 320-326.
5. Baskar, S., Ostrand-Rosenberg, S., Nabavi, N., Nadler, L.M., Freeman, G.J., and Glimcher, L.H. (1994). Constitutive expression of B7 restores immunogenicity of tumor cells expressing truncated MHC class II molecules. Proc. Natl. Acad. Sci. USA 90, 5687-5693.
6. Battegay, M., Cooper, S., Althage, A., Baenziger, J., Hengartner, H., and Zinkernagel, R.M. (1991). Quantification of lymphocytic choriomeningitis virus with an immunological focus assay in 24 or 96 well plates. J. Virol. Meth. 33, 191-198.
7. + T cells correlating with cytotoxic activity in vitro are more efficient in antivaccinia virus protection than CD4dependent interleukins. J. Immunol. 146, 4301-4307.
8. Bluestone, J.A. (1995). New perspectives of CD28-B7-mediated T cell costimulation. Immunity 2, 555-559.
9. Boehme, J., Haskins, K., Stecha, P., van Ewijk, W., LeMeur, M., Gerlinger, P., Benoist, C., and Mathis, D. (1989). Transgenic mice with I-A on islet cellsare normoglycemic but immunologically intolerant. Science 244, 1179-1183.
10. Bretscher, P., and Conn, M. (1970). A theory of self-nonself discrimination. Science 169, 1042
11. Buchmeier, M.J., Welsh, R.M., Dutko, F.J., and Oldstone, M.B.A. (1980). The virology and immunobiology of lymphocytic choriomeningitis virus infection. Adv. Immunol. 30, 275-312.
12. Buller, R.M.L., Smith, G.L., Cremer, K., Notkins, A.L., and Moss, B. (1985). Decreased virulence of recombinant vaccinia virus expression vectors is associated with athymidine-kinase negative phenotype. Nature 317, 813-815.
13. Chen, L., Asche, S., Brady, W.A., Hellström, L., Hellström, E.K., Ledbetter, J.A., McGowan, P., and Linsley, P.S. (1992). Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4. Cell 71, 1093-1102.
14. +-dependent and -independent T helper cell pathways in virus-specific and alloreactive cytotoxic T lymphocyte responses. Cell. Immunol. 125, 363-379.
15. Cobbold, S.P., Jayasuriya, A., Nash, A., Prospero, T.D., and Waldmann, H. (1984). Therapy with monoclonal antibodies by elimination of T cell subsets in vivo. Nature 372, 548-551.
16. Dialynas, D.P., Wilde, D.B., Marrack, P., Pierres, A., Wall, K.A., Havran, W., Otten, G., Loken, M.R., Pierres, M., Kappler, J.W., and Fitch, F.W. (1983). Characterization of the murine antigenic determinant, designated L3T4a, recognized by monoclonal antibody GK1.5: expression of L3T4a by functional T cell clones appears to correlate primarily with class II MHC antigen reactivity. Immunol. Rev. 74, 29-56.
17. Fearon, E.R., Pardoll, D.M., Itaya, T., Golumbek, P., Levitsky, H.I., Simons, J.W., Karasuyama, H., Vogelstein, B., and Frost, P. (1990). Interleukin-2 production by tumor cells bypasses T helper function in the generation of an antitumor response. Cell 60, 397-403.
18. Freeman, G.J., Boriello, F., Hodes, R.J., Reiser, H., Hathcock, K.S., Laszlo, G., McKnight, A.J., Kim, J., Du, L., Lombard, D.B., Gray, G.S., Nadler, L.M., and Sharpe, A.H. (1993). Uncovering of functional alternative CTLA-4 counter-receptor in B7-deficient mice. Science 262, 907-909.
19. Gansbacher, B., Zier, K., Danials, B., Cronin, K., Bannerji, R., and Gilboa, E. (1990). Interleukin-2 gene transfer into tumor cells abrogates tumorigenicitiy and induces protective immunity. J. Exp. Med. 172, 1217-1224.
20. Green, J.M., Noel, P.J., Sperling, A.I., Walunas, T.L., Gray, G.S., Bluestone, J.A., and Thompson, C.B. (1994). Absence of B7-dependent responses in CD28-deficient mice. Immunity 1, 501-508.
21. Guerder, S., Meyerhoff, J., and Flavell, R. (1994). The role of the T cell costimulator B7-1 in autoimmunity and in the induction and maintenance of tolerance to peripheral antigen. Immunity 1, 155-166.
22. Hämmerling, G., Schönrich, G., Ferber, I., and Arnold, B. (1993). Peripheral tolerance as a multi-step mechanism. Immunol. Rev. 133, 94-104.
23. Hany, M., Oehen, S., Schulz, M., Hengartner, H., Mackett, M., Bishop, D.H.L., and Zinkernagel, R.M. (1989). Anti-viral protection and prevention of lymphocytic choriomeningitis or of the local footpad swelling reaction in mice by immunisation with vaccinia-recombinant virus expressing LCMV-WE nucleoprotein or glycoprotein. Eur. J. Immunol. 19, 417-424.
24. + cytotoxic T lymphocytes in the absence of exogenous help. J. Exp. Med. 177, 1791-1796.
25. Harding, F.A., McArthur, J.G., Gross, J.A., Raulet, D.H., and Allison, J.P. (1992). CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones. Nature 356, 607-609.
26. Harlan, D.M., Hengartner, H., Huang, M.L., Kang, Y.H., Abe, R., Moreadith, R.W., Pircher, H.P., Gray, G.S., Ohashi, P.S., Freeman, G.J., Nadler, L.M., June, C.H., and Aichele, P. (1994). Mice expressing both B7 and viral glycoprotein on pancreatic beta cells along with glycoprotein-specific transgenic T cells develop diabetes due to a breakdown ot T-lymphocyte unresponsiveness. Proc. Natl. Acad. Sci. USA 97, 3137-3141.
27. Heath, W.R., Allison, J., Hoffmann, M.W., Schönrich, G., Hämmerling, G., Arnold, B., and Miller, J.F.A.P. (1992). Autoimmune disease as a consequence of locally produced IL-2. Nature 359, 547-549.
28. Janeway, C.A., Jr. (1989). Approaching the assymptote?: evolution and revolution in immunology. Cold Spring Harbor Symp. Quant. Biol. 54, 1-13.
29. June, C.H., Bluestone, J.A., Nadler, L.M., and Thompson, C.B. (1994). The B7 and CD28 receptor families. Immunol. Today 15, 321-332.
30. Karupiah, G., Coupar, B.E., Andrew, M.E., Boyle, D.B., Phillips, S.M., Mullbacher, A., Blanden, R.V., and Ramshaw, I.A. (1990). Elevated natural killer cell responses in mice infected with recombinant vaccinia virus encoding murine IL-2. J. Immunol. 144, 290-298.
31. Kawai, K., Shahinian, A., Mak, T.W., and Ohashi, P.S. (1996). Skin allograft rejection in CD28-deficient mice. Transplantation 61, 352-355.
32. Kearney, E.R., Pape, K.A., Loh, D.Y., and Jenkins, M.K. (1994). Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo. Immunity 1, 327-339.
33. Kisielow, P., Swat, W., Rocha, B., and von Boehmer, H. (1991). Induction of immunological unresponsiveness in vivo and in vitro by conventional and super-antigens in developing and mature T cells. Immunol. Rev. 122, 70-85.
34. Kündig, T., Althage, A., Hengartner, H., and Zinkernagel, R.M. (1992). A skin test to assess virus specific cytotoxic T cell activity. Proc. Natl. Acad. Sci. USA 89, 7757-7761.
35. Kündig, T.M., Bachmann, M.F., Lefrancois, L., Puddington, L., Hengartner, H., and Zinkernagel, R.M. (1993a). Nonimmunogenic tumor cells may efficiently restimulate tumor antigen-specific cytotoxic T cells. J. Immunol. 150, 4450-4456.
36. Kündig, T.M., Castelmur, I., Bachmann, M.F., Abraham, D., Binder, D., Hengartner, H., and Zinkernagel, R.M. (1993b). Fewer protective cytotoxic T cell epitopes than T-helper cell epitopes on vesicular stomatitis virus. J. Virol. 67, 3680-3683.
37. Kündig, T.M., Schorle, H., Bachmann, M.F., Hengartner, H., Zinkernagel, R.M., and Horak, I. (1993c). Immune responses in IL-2 deficient mice. Science 262, 1059-1061.
38. Kyburz, D., Aichele, P., Speiser, D.E., Hengartner, H., Zinkernagel, R.M., and Pircher, H.P. (1993). T cell immunity after a viral infection versus T cell tolerance induced by soluble viral peptides. Eur. J. Immunol. 23, 1956-1962.
39. Lafferty, K., and Woolnough, J. (1977). The origin and mechanism of allograft reaction. Immunol. Rev. 35, 231-262.
40. Lehmann-Grube, F. (1971). Lymphocytic choriomeningitis virus. Virol. Monogr. 10, 1-173.
41. Leist, T.P., Cobbold, S.P., Waldmann, H., Aguet, M., and Zinkernagel, R.M. (1987). Functional analysis of T lymphocyte subsets in antiviral host defense. J. Immunol. 138, 2278-2281.
42. Linsley, P.S., and Ledbetter, J.A. (1993). The role of the CD28 receptor during T cell responses to antigen. Annu. Rev. Immunol. 11, 191-212.
43. Lucas, P.J., Negishi, I., Nakayama, K., Fields, L.E., and Loh, D.Y. (1995). Naive CD28-deficient T calls can initiate but not sustain an in vitro antigen-specific immune response. J. Immunol. 154, 5757-5768.
44. MacDonald, H.R., Lees, R.K., Baschieri, S., Herrmann, T., and Lussow, A.R. (1993). Peripheral T-cell reactivity to bacterial superantigens in vivo: the response/anergy paradox. Immunol Rev. 133, 105-118.
45. Mackett, M., Yilma, T., Rose, J.K., and Moss, B. (1985). Vaccinia virus recombinants: expression of VSV genes and protective immunization of mice and cattle. Science 227, 433-435.
46. Marrack, P., Hugo, P., McCormack, J., and Kappler, J. (1993). Death and T cells. Immunol. Rev. 133, 119-129.
47. Migita, K., and Ochi, A. (1993). The fate of anergic T cells in vivo. J. Immunol. 150, 763-770.
48. Moskophidis, D., Assmann Wischer, U., Simon, M.M., and Lehmann Grube, F. (1987). The immune response of the mouse to lymphocytic choriomeningitis virus. V. High numbers of cytolytic T lymphocytes are generated in the spleen during acute infection. Eur. J. Immunol. 17, 937-942.
49. Oehen, S., Waldner, H.P., Kündig, T.M., Hengartner, H., and Zinkernagel, R. M. (1992). Cytotoxic T cell memory to lymphocytic choriomeningitis virus is governed by elevated CTL-P frequencies and persisting antigen. J. Exp. Med. 176, 1273-1281.
50. Ohashi, P.S., Oehen, S., Bürki, K., Pircher, H.P., Ohashi, C.T., Odermatt, B., Malissen, B., Zinkernagel, R., and Hengartner, H. (1991). Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice. Cell 65, 305-317.
51. Ohashi, P.S., Oehen, S., Aichele, P., Pircher, H., Odermatt, B., Herrera, P., Higuchi, Y., Buerki, K., Hengartner, H., and Zinkernagel, R.M. (1993). Induction of diabetes is influenced by the infectious virus and local expression of MHC class I and tumor necrosis factor alpha. J. Immunol. 150, 5185-5194.
52. Pircher, H.P., Bürki, K., Lang, R., Hengartner, H., and Zinkernagel, R. (1989). Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen. Nature 342, 559-561.
53. Pircher, H.P., Moskophidis, D., Rohrer, U., Bürki, K., Hengartner, H., and Zinkernagel, R.M. (1990). Viral escape by selection of cytotoxic T cell-resistant virus variants in vivo. Nature 346, 629-633.
54. Puddington, L., Sevan, M.J., and Lefrançois, L. (1986). N protein is the predominant antigen recognized by vesicular stomatitis virus-specific cytotoxic T cells. J. Virol. 60, 708-717.
55. + T lymphocytes on immunizing Mls-1b mice with Mls-1a expressing cells. Nature 339, 541-544.
56. Ramsdell, F., and Fowlkes, B.J. (1990). Clonal deletion versus clonal anergy: the role of the thymus in inducing self tolerance. Science 248, 1342-1348.
57. Ramsdell, F., and Fowlkes, B.J. (1992). Maintainance of in vivo tolerance by persistence of antigen. Science 257, 1130-1134.
58. Rocha, B., Tanchot, C., and von Boehmer, H. (1993). Clonal anergy blocks in vivo growth of mature T cells and can be reversed in the absence of antigen. J. Exp. Med. 177, 1517-1521.
59. Schwartz, R.H. (1990). A cell culture model for T lymphocyte clonal anergy. Science 248, 1349-1356.
60. Schwartz, R.H. (1992). Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy. Cell 71, 1065-1068.
61. Shahinian, A., Pfeffer, K., Lee, K.P., Kündig, T.M., Kishihara, K., Wakeham, A., Kawai, K., Ohashi, P.S., Thompson, C.B., and Mak, T.W. (1993). Differential costimulatory requirements in CD28-defi-cient mice. Science 261, 609-612.
62. Sprent, J., and Webb, S.R. (1995). Intrathymic and extrathymic clonal deletion of T cells. Curr. Opin. Immunol. 7, 196-205.
63. Sprent, J., Kosaka, H., Gao, E.K., Surh, C.D., and Webb, S.R. (1993). Intrathymic and extrathymic tolerance in bone marrow chimeras. Immunol. Rev. 133, 151-176.
64. + T cells by B7-transfected melanoma cells. Science 259, 368-372.
65. von Herrath, M.G., Dockter, J., and Oldstone, M.B.A. (1994). How virus induces a rapid or slow onset insulin-dependent diabetes mellitus in a transgenic model. Immunity 1, 231-242.
66. Wagner, R.R. (1987). The Rhabdoviruses (New York: Plenum Press). Widmann, C., Maryanski, J.L., Romero, P., and Corradin, G. (1991). Differential stability of antigenic MHC class I-restricted synthetic peptides. J. Immunol. 147, 3745-3751.
67. Zinkernagel, R.M., Moskophidis, D., Kündig, T.M., Oehen, S., Pircher, H., and Hengartner, H. (1993). Effector T-cell induction and T-cell memory versus peripheral deletion of T cells. Immunol. Rev. 133, 199-223.