IL-12 and type I interferon prolong the division of activated CD8 T cells by maintaining high-affinity IL-2 signaling in vivo

Journal of Experimental Medicine

Volumn 211, Issue 1, 2014, Pages 105-120

  Starbeck Miller, Gabriel R ^a   Xue, Hai Hui ^a   Harty, John T ^a,b  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERFERON; INTERLEUKIN 12; INTERLEUKIN 2 RECEPTOR ALPHA; PHOSPHATIDYLINOSITOL 3 KINASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FOXM1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD8+ T LYMPHOCYTE; CELL CYCLE; CELL CYCLE PROGRESSION; CELL DIVISION; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; CYTOKINE RESPONSE; ENZYME ACTIVATION; IMMUNIZATION; IN VIVO STUDY; INFLAMMATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE ACTIVATION;

ADOPTIVE TRANSFER; ANIMALS; BROMODEOXYURIDINE; CD8-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; CELL SURVIVAL; DNA PRIMERS; FORKHEAD TRANSCRIPTION FACTORS; IMMUNOBLOTTING; INTERFERON TYPE I; INTERLEUKIN-12; INTERLEUKIN-2; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICROARRAY ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

EID: 84892534048     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20130901     Document Type: Article

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