-
1
-
-
0035162560
-
Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
-
Brunkow, M. E., E. W. Jeffery, K. A. Hjerrild, B. Paeper, L. B. Clark, S. A. Yasayko, J. E. Wilkinson, D. Galas, S. F. Ziegler, and F. Ramsdell. 2001. Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse. Nat. Genet. 27: 68-73.
-
(2001)
Nat. Genet.
, vol.27
, pp. 68-73
-
-
Brunkow, M.E.1
Jeffery, E.W.2
Hjerrild, K.A.3
Paeper, B.4
Clark, L.B.5
Yasayko, S.A.6
Wilkinson, J.E.7
Galas, D.8
Ziegler, S.F.9
Ramsdell, F.10
-
2
-
-
41549159660
-
Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces
-
Rubtsov, Y. P., J. P. Rasmussen, E. Y. Chi, J. Fontenot, L. Castelli, X. Ye, P. Treuting, L. Siewe, A. Roers, W. R. Henderson, Jr., et al. 2008. Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces. Immunity 28: 546-558.
-
(2008)
Immunity
, vol.28
, pp. 546-558
-
-
Rubtsov, Y.P.1
Rasmussen, J.P.2
Chi, E.Y.3
Fontenot, J.4
Castelli, L.5
Ye, X.6
Treuting, P.7
Siewe, L.8
Roers, A.9
Henderson Jr., W.R.10
-
3
-
-
34248592104
-
T cell-produced transforming growth factor-beta1 controls T cell tolerance and regulates Th1- And Th17-cell differentiation
-
Li, M. O., Y. Y. Wan, and R. A. Flavell. 2007. T cell-produced transforming growth factor-beta1 controls T cell tolerance and regulates Th1- and Th17-cell differentiation. Immunity 26: 579-591.
-
(2007)
Immunity
, vol.26
, pp. 579-591
-
-
Li, M.O.1
Wan, Y.Y.2
Flavell, R.A.3
-
4
-
-
33749132564
-
Blockade of CTLA-4 on CD4+CD25+ regulatory T cells abrogates their function in vivo
-
Read, S., R. Greenwald, A. Izcue, N. Robinson, D. Mandelbrot, L. Francisco, A. H. Sharpe, and F. Powrie. 2006. Blockade of CTLA-4 on CD4+CD25+ regulatory T cells abrogates their function in vivo. J. Immunol. 177: 4376-4383.
-
(2006)
J. Immunol.
, vol.177
, pp. 4376-4383
-
-
Read, S.1
Greenwald, R.2
Izcue, A.3
Robinson, N.4
Mandelbrot, D.5
Francisco, L.6
Sharpe, A.H.7
Powrie, F.8
-
5
-
-
53749094183
-
CTLA-4 control over Foxp3+ regulatory T cell function
-
Wing, K., Y. Onishi, P. Prieto-Martin, T. Yamaguchi, M. Miyara, Z. Fehervari, T. Nomura, and S. Sakaguchi. 2008. CTLA-4 control over Foxp3+ regulatory T cell function. Science 322: 271-275.
-
(2008)
Science
, vol.322
, pp. 271-275
-
-
Wing, K.1
Onishi, Y.2
Prieto-Martin, P.3
Yamaguchi, T.4
Miyara, M.5
Fehervari, Z.6
Nomura, T.7
Sakaguchi, S.8
-
6
-
-
0031821875
-
CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
-
Thornton, A. M., and E. M. Shevach. 1998. CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J. Exp. Med. 188: 287-296.
-
(1998)
J. Exp. Med.
, vol.188
, pp. 287-296
-
-
Thornton, A.M.1
Shevach, E.M.2
-
7
-
-
36248976097
-
CD4+ CD25+Foxp3+ regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4+ T cells
-
Pandiyan, P., L. Zheng, S. Ishihara, J. Reed, and M. J. Lenardo. 2007. CD4+ CD25+Foxp3+ regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4+ T cells. Nat. Immunol. 8: 1353-1362.
-
(2007)
Nat. Immunol.
, vol.8
, pp. 1353-1362
-
-
Pandiyan, P.1
Zheng, L.2
Ishihara, S.3
Reed, J.4
Lenardo, M.J.5
-
8
-
-
33746383248
-
Regulatory T cells in virus infections
-
Rouse, B. T., P. P. Sarangi, and S. Suvas. 2006. Regulatory T cells in virus infections. Immunol. Rev. 212: 272-286.
-
(2006)
Immunol. Rev.
, vol.212
, pp. 272-286
-
-
Rouse, B.T.1
Sarangi, P.P.2
Suvas, S.3
-
9
-
-
77951670712
-
Once a killer, always a killer: From cytotoxic T cell to memory cell
-
Lefrançois, L., and J. J. Obar. 2010. Once a killer, always a killer: from cytotoxic T cell to memory cell. Immunol. Rev. 235: 206-218.
-
(2010)
Immunol. Rev.
, vol.235
, pp. 206-218
-
-
Lefrançois, L.1
Obar, J.J.2
-
10
-
-
77951681614
-
Generating diversity: Transcriptional regulation of effector and memory CD8 T-cell differentiation
-
Rutishauser, R. L., and S. M. Kaech. 2010. Generating diversity: transcriptional regulation of effector and memory CD8 T-cell differentiation. Immunol. Rev. 235: 219-233.
-
(2010)
Immunol. Rev.
, vol.235
, pp. 219-233
-
-
Rutishauser, R.L.1
Kaech, S.M.2
-
11
-
-
41149096579
-
T-cell quality in memory and protection: Implications for vaccine design
-
Seder, R. A., P. A. Darrah, and M. Roederer. 2008. T-cell quality in memory and protection: implications for vaccine design. Nat. Rev. Immunol. 8: 247-258.
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 247-258
-
-
Seder, R.A.1
Darrah, P.A.2
Roederer, M.3
-
12
-
-
33745224089
-
Interleukin-2 signals during priming are required for secondary expansion of CD8+ memory T cells
-
Williams, M. A., A. J. Tyznik, and M. J. Bevan. 2006. Interleukin-2 signals during priming are required for secondary expansion of CD8+ memory T cells. Nature 441: 890-893.
-
(2006)
Nature
, vol.441
, pp. 890-893
-
-
Williams, M.A.1
Tyznik, A.J.2
Bevan, M.J.3
-
13
-
-
74549162832
-
Prolonged interleukin-2Ralpha expression on virus-specific CD8+ T cells favors terminal-effector differentiation in vivo
-
Kalia, V., S. Sarkar, S. Subramaniam, W. N. Haining, K. A. Smith, and R. Ahmed. 2010. Prolonged interleukin-2Ralpha expression on virus-specific CD8+ T cells favors terminal-effector differentiation in vivo. Immunity 32: 91-103.
-
(2010)
Immunity
, vol.32
, pp. 91-103
-
-
Kalia, V.1
Sarkar, S.2
Subramaniam, S.3
Haining, W.N.4
Smith, K.A.5
Ahmed, R.6
-
14
-
-
74549156399
-
CD4+ T cell regulation of CD25 expression controls development of short-lived effector CD8+ T cells in primary and secondary responses
-
Obar, J. J., M. J. Molloy, E. R. Jellison, T. A. Stoklasek, W. Zhang, E. J. Usherwood, and L. Lefrançois. 2010. CD4+ T cell regulation of CD25 expression controls development of short-lived effector CD8+ T cells in primary and secondary responses. Proc. Natl. Acad. Sci. USA 107: 193-198.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 193-198
-
-
Obar, J.J.1
Molloy, M.J.2
Jellison, E.R.3
Stoklasek, T.A.4
Zhang, W.5
Usherwood, E.J.6
Lefrançois, L.7
-
15
-
-
74549216531
-
Interleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effector cytolytic T cells
-
Pipkin, M. E., J. A. Sacks, F. Cruz-Guilloty, M. G. Lichtenheld, M. J. Bevan, and A. Rao. 2010. Interleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effector cytolytic T cells. Immunity 32: 79-90.
-
(2010)
Immunity
, vol.32
, pp. 79-90
-
-
Pipkin, M.E.1
Sacks, J.A.2
Cruz-Guilloty, F.3
Lichtenheld, M.G.4
Bevan, M.J.5
Rao, A.6
-
16
-
-
37549026844
-
Replicating and non-replicating viral vectors for vaccine development
-
Robert-Guroff, M. 2007. Replicating and non-replicating viral vectors for vaccine development. Curr. Opin. Biotechnol. 18: 546-556.
-
(2007)
Curr. Opin. Biotechnol.
, vol.18
, pp. 546-556
-
-
Robert-Guroff, M.1
-
18
-
-
9244248089
-
Modified vaccinia virus Ankara as antigen delivery system: How can we best use its potential?
-
Drexler, I., C. Staib, and G. Sutter. 2004. Modified vaccinia virus Ankara as antigen delivery system: how can we best use its potential? Curr. Opin. Biotechnol. 15: 506-512.
-
(2004)
Curr. Opin. Biotechnol.
, vol.15
, pp. 506-512
-
-
Drexler, I.1
Staib, C.2
Sutter, G.3
-
19
-
-
33748642155
-
Differences and similarities in viral life cycle progression and host cell physiology after infection of human dendritic cells with modified vaccinia virus Ankara and vaccinia virus
-
Chahroudi, A., D. A. Garber, P. Reeves, L. Liu, D. Kalman, and M. B. Feinberg. 2006. Differences and similarities in viral life cycle progression and host cell physiology after infection of human dendritic cells with modified vaccinia virus Ankara and vaccinia virus. J. Virol. 80: 8469-8481.
-
(2006)
J. Virol.
, vol.80
, pp. 8469-8481
-
-
Chahroudi, A.1
Garber, D.A.2
Reeves, P.3
Liu, L.4
Kalman, D.5
Feinberg, M.B.6
-
20
-
-
34548424032
-
Cross-competition of CD8+ T cells shapes the immunodominance hierarchy during boost vaccination
-
Kastenmuller, W., G. Gasteiger, J. H. Gronau, R. Baier, R. Ljapoci, D. H. Busch, and I. Drexler. 2007. Cross-competition of CD8+ T cells shapes the immunodominance hierarchy during boost vaccination. J. Exp. Med. 204: 2187-2198.
-
(2007)
J. Exp. Med.
, vol.204
, pp. 2187-2198
-
-
Kastenmuller, W.1
Gasteiger, G.2
Gronau, J.H.3
Baier, R.4
Ljapoci, R.5
Busch, D.H.6
Drexler, I.7
-
21
-
-
19944431356
-
Identification of poxvirus CD8+ T cell determinants to enable rational design and characterization of smallpox vaccines
-
Tscharke, D. C., G. Karupiah, J. Zhou, T. Palmore, K. R. Irvine, S. M. Haeryfar, S. Williams, J. Sidney, A. Sette, J. R. Bennink, and J. W. Yewdell. 2005. Identification of poxvirus CD8+ T cell determinants to enable rational design and characterization of smallpox vaccines. J. Exp. Med. 201: 95-104.
-
(2005)
J. Exp. Med.
, vol.201
, pp. 95-104
-
-
Tscharke, D.C.1
Karupiah, G.2
Zhou, J.3
Palmore, T.4
Irvine, K.R.5
Haeryfar, S.M.6
Williams, S.7
Sidney, J.8
Sette, A.9
Bennink, J.R.10
Yewdell, J.W.11
-
22
-
-
33745133006
-
Extrafollicular activation of lymph node B cells by antigen-bearing dendritic cells
-
Qi, H., J. G. Egen, A. Y. Huang, and R. N. Germain. 2006. Extrafollicular activation of lymph node B cells by antigen-bearing dendritic cells. Science 312: 672-1676.
-
(2006)
Science
, vol.312
, pp. 672-1676
-
-
Qi, H.1
Egen, J.G.2
Huang, A.Y.3
Germain, R.N.4
-
23
-
-
33846423147
-
Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease
-
Lahl, K., C. Loddenkemper, C. Drouin, J. Freyer, J. Arnason, G. Eberl, A. Hamann, H. Wagner, J. Huehn, and T. Sparwasser. 2007. Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease. J. Exp. Med. 204: 57-63.
-
(2007)
J. Exp. Med.
, vol.204
, pp. 57-63
-
-
Lahl, K.1
Loddenkemper, C.2
Drouin, C.3
Freyer, J.4
Arnason, J.5
Eberl, G.6
Hamann, A.7
Wagner, H.8
Huehn, J.9
Sparwasser, T.10
-
24
-
-
65549091509
-
In vivo expansion of T reg cells with IL-2-mAb complexes: Induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppression
-
Webster, K. E., S. Walters, R. E. Kohler, T. Mrkvan, O. Boyman, C. D. Surh, S. T. Grey, and J. Sprent. 2009. In vivo expansion of T reg cells with IL-2-mAb complexes: induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppression. J. Exp. Med. 206: 751-760.
-
(2009)
J. Exp. Med.
, vol.206
, pp. 751-760
-
-
Webster, K.E.1
Walters, S.2
Kohler, R.E.3
Mrkvan, T.4
Boyman, O.5
Surh, C.D.6
Grey, S.T.7
Sprent, J.8
-
25
-
-
1842681952
-
Selective expression of IL-7 receptor on memory T cells identifies early CD40L-dependent generation of distinct CD8+ memory T cell subsets
-
Huster, K. M., V. Busch, M. Schiemann, K. Linkemann, K. M. Kerksiek, H. Wagner, and D. H. Busch. 2004. Selective expression of IL-7 receptor on memory T cells identifies early CD40L-dependent generation of distinct CD8+ memory T cell subsets. Proc. Natl. Acad. Sci. USA 101: 5610-5615.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 5610-5615
-
-
Huster, K.M.1
Busch, V.2
Schiemann, M.3
Linkemann, K.4
Kerksiek, K.M.5
Wagner, H.6
Busch, D.H.7
-
26
-
-
34548027000
-
Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor
-
Joshi, N. S., W. Cui, A. Chandele, H. K. Lee, D. R. Urso, J. Hagman, L. Gapin, and S. M. Kaech. 2007. Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor. Immunity 27: 281-295.
-
(2007)
Immunity
, vol.27
, pp. 281-295
-
-
Joshi, N.S.1
Cui, W.2
Chandele, A.3
Lee, H.K.4
Urso, D.R.5
Hagman, J.6
Gapin, L.7
Kaech, S.M.8
-
27
-
-
33846485153
-
Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice
-
Kim, J. M., J. P. Rasmussen, and A. Y. Rudensky. 2007. Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice. Nat. Immunol. 8: 191-197.
-
(2007)
Nat. Immunol.
, vol.8
, pp. 191-197
-
-
Kim, J.M.1
Rasmussen, J.P.2
Rudensky, A.Y.3
-
28
-
-
41549114751
-
Pathogen-specific CD8 T cell responses are directly inhibited by IL-10
-
Biswas, P. S., V. Pedicord, A. Ploss, E. Menet, I. Leiner, and E. G. Pamer. 2007. Pathogen-specific CD8 T cell responses are directly inhibited by IL-10. J. Immunol. 179: 4520-4528.
-
(2007)
J. Immunol.
, vol.179
, pp. 4520-4528
-
-
Biswas, P.S.1
Pedicord, V.2
Ploss, A.3
Menet, E.4
Leiner, I.5
Pamer, E.G.6
-
29
-
-
55149111143
-
Diversity in the contribution of interleukin-10 to T-cell-mediated immune regulation
-
Maynard, C. L., and C. T. Weaver. 2008. Diversity in the contribution of interleukin-10 to T-cell-mediated immune regulation. Immunol. Rev. 226: 219-233.
-
(2008)
Immunol. Rev.
, vol.226
, pp. 219-233
-
-
Maynard, C.L.1
Weaver, C.T.2
-
30
-
-
68249141869
-
Opposing effects of TGF-beta and IL-15 cytokines control the number of short-lived effector CD8+ T cells
-
Sanjabi, S., M. M. Mosaheb, and R. A. Flavell. 2009. Opposing effects of TGF-beta and IL-15 cytokines control the number of short-lived effector CD8+ T cells. Immunity 31: 131-144.
-
(2009)
Immunity
, vol.31
, pp. 131-144
-
-
Sanjabi, S.1
Mosaheb, M.M.2
Flavell, R.A.3
-
31
-
-
27544481941
-
A function for interleukin 2 in Foxp3-expressing regulatory T cells
-
Fontenot, J. D., J. P. Rasmussen, M. A. Gavin, and A. Y. Rudensky. 2005. A function for interleukin 2 in Foxp3-expressing regulatory T cells. Nat. Immunol. 6: 1142-1151.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 1142-1151
-
-
Fontenot, J.D.1
Rasmussen, J.P.2
Gavin, M.A.3
Rudensky, A.Y.4
-
32
-
-
77955890953
-
Interleukin-2 receptor signaling: At the interface between tolerance and immunity
-
Malek, T. R., and I. Castro. 2010. Interleukin-2 receptor signaling: at the interface between tolerance and immunity. Immunity 33: 153-165.
-
(2010)
Immunity
, vol.33
, pp. 153-165
-
-
Malek, T.R.1
Castro, I.2
-
33
-
-
0034897188
-
The basis for IL-2-induced IL-2 receptor alpha chain gene regulation: Importance of two widely separated IL-2 response elements
-
Kim, H. P., J. Kelly, and W. J. Leonard. 2001. The basis for IL-2-induced IL-2 receptor alpha chain gene regulation: importance of two widely separated IL-2 response elements. Immunity 15: 159-172.
-
(2001)
Immunity
, vol.15
, pp. 159-172
-
-
Kim, H.P.1
Kelly, J.2
Leonard, W.J.3
-
34
-
-
77953541634
-
Inflammatory cytokines as a third signal for T cell activation
-
Curtsinger, J. M., and M. F. Mescher. 2010. Inflammatory cytokines as a third signal for T cell activation. Curr. Opin. Immunol. 22: 333-340.
-
(2010)
Curr. Opin. Immunol.
, vol.22
, pp. 333-340
-
-
Curtsinger, J.M.1
Mescher, M.F.2
-
35
-
-
68949120834
-
The initial phase of an immune response functions to activate regulatory T cells
-
O'Gorman, W. E., H. Dooms, S. H. Thorne, W. F. Kuswanto, E. F. Simonds, P. O. Krutzik, G. P. Nolan, and A. K. Abbas. 2009. The initial phase of an immune response functions to activate regulatory T cells. J. Immunol. 183: 332-339.
-
(2009)
J. Immunol.
, vol.183
, pp. 332-339
-
-
O'Gorman, W.E.1
Dooms, H.2
Thorne, S.H.3
Kuswanto, W.F.4
Simonds, E.F.5
Krutzik, P.O.6
Nolan, G.P.7
Abbas, A.K.8
-
36
-
-
33749134189
-
Cutting edge: Paracrine, but not autocrine, IL-2 signaling is sustained during early antiviral CD4 T cell response
-
Long, M., and A. J. Adler. 2006. Cutting edge: Paracrine, but not autocrine, IL-2 signaling is sustained during early antiviral CD4 T cell response. J. Immunol. 177: 4257-4261.
-
(2006)
J. Immunol.
, vol.177
, pp. 4257-4261
-
-
Long, M.1
Adler, A.J.2
-
37
-
-
78649875958
-
Single-cell quantification of IL-2 response by effector and regulatory T cells reveals critical plasticity in immune response
-
Feinerman, O., G. Jentsch, K. E. Tkach, J. W. Coward, M. M. Hathorn, M. W. Sneddon, T. Emonet, K. A. Smith, and G. Altan-Bonnet. 2010. Single-cell quantification of IL-2 response by effector and regulatory T cells reveals critical plasticity in immune response. Mol. Syst. Biol. 6: 437.
-
(2010)
Mol. Syst. Biol.
, vol.6
, pp. 437
-
-
Feinerman, O.1
Jentsch, G.2
Tkach, K.E.3
Coward, J.W.4
Hathorn, M.M.5
Sneddon, M.W.6
Emonet, T.7
Smith, K.A.8
Altan-Bonnet, G.9
-
38
-
-
77649242104
-
Competing feedback loops shape IL-2 signaling between helper and regulatory T lymphocytes in cellular microenvironments
-
Busse, D., M. De la Rosa, K. Hobiger, K. Thurley, M. Flossdorf, A. Scheffold, and T. Höfer. 2010. Competing feedback loops shape IL-2 signaling between helper and regulatory T lymphocytes in cellular microenvironments. Proc. Natl. Acad. Sci. USA 107: 3058-3063.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 3058-3063
-
-
Busse, D.1
De La Rosa, M.2
Hobiger, K.3
Thurley, K.4
Flossdorf, M.5
Scheffold, A.6
Höfer, T.7
-
39
-
-
49649106712
-
Circumvention of regulatory CD4(+) T cell activity during cross-priming strongly enhances T cellmediated immunity
-
Heit, A., F. Gebhardt, K. Lahl, M. Neuenhahn, F. Schmitz, F. Anderl, H. Wagner, T. Sparwasser, D. H. Busch, and K. Kastenmüller. 2008. Circumvention of regulatory CD4(+) T cell activity during cross-priming strongly enhances T cellmediated immunity. Eur. J. Immunol. 38: 1585-1597.
-
(2008)
Eur. J. Immunol.
, vol.38
, pp. 1585-1597
-
-
Heit, A.1
Gebhardt, F.2
Lahl, K.3
Neuenhahn, M.4
Schmitz, F.5
Anderl, F.6
Wagner, H.7
Sparwasser, T.8
Busch, D.H.9
Kastenmüller, K.10
-
40
-
-
23844469143
-
Depletion of CD25+CD4+T cells (Tregs) enhances the HBV-specific CD8+ T cell response primed by DNA immunization
-
Furuichi, Y., H. Tokuyama, S. Ueha, M. Kurachi, F. Moriyasu, and K. Kakimi. 2005. Depletion of CD25+CD4+T cells (Tregs) enhances the HBV-specific CD8+ T cell response primed by DNA immunization. World J. Gastroenterol. 11: 3772-3777.
-
(2005)
World J. Gastroenterol.
, vol.11
, pp. 3772-3777
-
-
Furuichi, Y.1
Tokuyama, H.2
Ueha, S.3
Kurachi, M.4
Moriyasu, F.5
Kakimi, K.6
-
41
-
-
0141449974
-
CD4+ CD25+ T cells regulate virus-specific primary and memory CD8+ T cell responses
-
Suvas, S., U. Kumaraguru, C. D. Pack, S. Lee, and B. T. Rouse. 2003. CD4+ CD25+ T cells regulate virus-specific primary and memory CD8+ T cell responses. J. Exp. Med. 198: 889-901.
-
(2003)
J. Exp. Med.
, vol.198
, pp. 889-901
-
-
Suvas, S.1
Kumaraguru, U.2
Pack, C.D.3
Lee, S.4
Rouse, B.T.5
-
42
-
-
8644290853
-
CD4+ CD25+ T cells regulate vaccine-generated primary and memory CD8+ T-cell responses against herpes simplex virus type 1
-
Toka, F. N., S. Suvas, and B. T. Rouse. 2004. CD4+ CD25+ T cells regulate vaccine-generated primary and memory CD8+ T-cell responses against herpes simplex virus type 1. J. Virol. 78: 13082-13089.
-
(2004)
J. Virol.
, vol.78
, pp. 13082-13089
-
-
Toka, F.N.1
Suvas, S.2
Rouse, B.T.3
-
43
-
-
0037172969
-
CD25+ CD4+ T cells contribute to the control of memory CD8+ T cells
-
Murakami, M., A. Sakamoto, J. Bender, J. Kappler, and P. Marrack. 2002. CD25+ CD4+ T cells contribute to the control of memory CD8+ T cells. Proc. Natl. Acad. Sci. USA 99: 8832-8837.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 8832-8837
-
-
Murakami, M.1
Sakamoto, A.2
Bender, J.3
Kappler, J.4
Marrack, P.5
-
44
-
-
33947640163
-
Incomplete depletion and rapid regeneration of Foxp3+ regulatory T cells following anti-CD25 treatment in malaria-infected mice
-
Couper, K. N., D. G. Blount, J. B. De Souza, I. Suffia, Y. Belkaid, and E. M. Riley. 2007. Incomplete depletion and rapid regeneration of Foxp3+ regulatory T cells following anti-CD25 treatment in malaria-infected mice. J. Immunol. 178: 4136-4146.
-
(2007)
J. Immunol.
, vol.178
, pp. 4136-4146
-
-
Couper, K.N.1
Blount, D.G.2
De Souza, J.B.3
Suffia, I.4
Belkaid, Y.5
Riley, E.M.6
-
45
-
-
79956296631
-
CD4+ CD25+ regulatory T cells control CD8+ T-cell effector differentiation by modulating IL-2 homeostasis
-
McNally, A., G. R. Hill, T. Sparwasser, R. Thomas, and R. J. Steptoe. 2011. CD4+ CD25+ regulatory T cells control CD8+ T-cell effector differentiation by modulating IL-2 homeostasis. Proc. Natl. Acad. Sci. USA 108: 7529-7534.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 7529-7534
-
-
McNally, A.1
Hill, G.R.2
Sparwasser, T.3
Thomas, R.4
Steptoe, R.J.5
-
46
-
-
79952291184
-
Regulatory T cells facilitate the nuclear accumulation of inducible cAMP early repressor (ICER) and suppress nuclear factor of activated T cell c1 (NFATc1)
-
Vaeth, M., T. Gogishvili, T. Bopp, M. Klein, F. Berberich-Siebelt, S. Gattenloehner, A. Avots, T. Sparwasser, N. Grebe, E. Schmitt, et al. 2011. Regulatory T cells facilitate the nuclear accumulation of inducible cAMP early repressor (ICER) and suppress nuclear factor of activated T cell c1 (NFATc1). Proc. Natl. Acad. Sci. USA 108: 2480-2485.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 2480-2485
-
-
Vaeth, M.1
Gogishvili, T.2
Bopp, T.3
Klein, M.4
Berberich-Siebelt, F.5
Gattenloehner, S.6
Avots, A.7
Sparwasser, T.8
Grebe, N.9
Schmitt, E.10
-
47
-
-
79952761637
-
Foxp3(+) regulatory T cells promote T helper 17 cell development in vivo through regulation of interleukin-2
-
Chen, Y., C. J. Haines, I. Gutcher, K. Hochweller, W. M. Blumenschein, T. McClanahan, G. Hämmerling, M. O. Li, D. J. Cua, and M. J. McGeachy. 2011. Foxp3(+) regulatory T cells promote T helper 17 cell development in vivo through regulation of interleukin-2. Immunity 34: 409-421.
-
(2011)
Immunity
, vol.34
, pp. 409-421
-
-
Chen, Y.1
Haines, C.J.2
Gutcher, I.3
Hochweller, K.4
Blumenschein, W.M.5
McClanahan, T.6
Hämmerling, G.7
Li, M.O.8
Cua, D.J.9
McGeachy, M.J.10
-
48
-
-
79952769679
-
CD4(+)CD25(+)Foxp3(+) regulatory T cells promote Th17 cells in vitro and enhance host resistance in mouse Candida albicans Th17 cell infection model
-
Pandiyan, P., H. R. Conti, L. Zheng, A. C. Peterson, D. R. Mathern, N. Hernández-Santos, M. Edgerton, S. L. Gaffen, and M. J. Lenardo. 2011. CD4(+)CD25(+)Foxp3(+) regulatory T cells promote Th17 cells in vitro and enhance host resistance in mouse Candida albicans Th17 cell infection model. Immunity 34: 422-434.
-
(2011)
Immunity
, vol.34
, pp. 422-434
-
-
Pandiyan, P.1
Conti, H.R.2
Zheng, L.3
Peterson, A.C.4
Mathern, D.R.5
Hernández-Santos, N.6
Edgerton, M.7
Gaffen, S.L.8
Lenardo, M.J.9
-
49
-
-
48249103057
-
Foxp3+ natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation
-
Onishi, Y., Z. Fehervari, T. Yamaguchi, and S. Sakaguchi. 2008. Foxp3+ natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation. Proc. Natl. Acad. Sci. USA 105: 10113-10118.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 10113-10118
-
-
Onishi, Y.1
Fehervari, Z.2
Yamaguchi, T.3
Sakaguchi, S.4
-
50
-
-
63049090504
-
CD4+ regulatory T cells require CTLA-4 for the maintenance of systemic tolerance
-
Friedline, R. H., D. S. Brown, H. Nguyen, H. Kornfeld, J. Lee, Y. Zhang, M. Appleby, S. D. Der, J. Kang, and C. A. Chambers. 2009. CD4+ regulatory T cells require CTLA-4 for the maintenance of systemic tolerance. J. Exp. Med. 206: 421-434.
-
(2009)
J. Exp. Med.
, vol.206
, pp. 421-434
-
-
Friedline, R.H.1
Brown, D.S.2
Nguyen, H.3
Kornfeld, H.4
Lee, J.5
Zhang, Y.6
Appleby, M.7
Der, S.D.8
Kang, J.9
Chambers, C.A.10
-
51
-
-
76249119192
-
FoxP3+ regulatory T cells essentially contribute to peripheral CD8+ T-cell tolerance induced by steady-state dendritic cells
-
Schildknecht, A., S. Brauer, C. Brenner, K. Lahl, H. Schild, T. Sparwasser, H. C. Probst, and M. Van den Broek. 2010. FoxP3+ regulatory T cells essentially contribute to peripheral CD8+ T-cell tolerance induced by steady-state dendritic cells. Proc. Natl. Acad. Sci. USA 107: 199-203.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 199-203
-
-
Schildknecht, A.1
Brauer, S.2
Brenner, C.3
Lahl, K.4
Schild, H.5
Sparwasser, T.6
Probst, H.C.7
Van Den Broek, M.8
-
52
-
-
79955529454
-
Transendocytosis of CD80 and CD86: A molecular basis for the cell-extrinsic function of CTLA-4
-
Qureshi, O. S., Y. Zheng, K. Nakamura, K. Attridge, C. Manzotti, E. M. Schmidt, J. Baker, L. E. Jeffery, S. Kaur, Z. Briggs, et al. 2011. Transendocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4. Science 332: 600-603.
-
(2011)
Science
, vol.332
, pp. 600-603
-
-
Qureshi, O.S.1
Zheng, Y.2
Nakamura, K.3
Attridge, K.4
Manzotti, C.5
Schmidt, E.M.6
Baker, J.7
Jeffery, L.E.8
Kaur, S.9
Briggs, Z.10
-
53
-
-
0027281691
-
Differential T cell costimulatory requirements in CD28-deficient mice
-
Shahinian, A., K. Pfeffer, K. P. Lee, T. M. Kündig, K. Kishihara, A. Wakeham, K. Kawai, P. S. Ohashi, C. B. Thompson, and T. W. Mak. 1993. Differential T cell costimulatory requirements in CD28-deficient mice. Science 261: 609-612.
-
(1993)
Science
, vol.261
, pp. 609-612
-
-
Shahinian, A.1
Pfeffer, K.2
Lee, K.P.3
Kündig, T.M.4
Kishihara, K.5
Wakeham, A.6
Kawai, K.7
Ohashi, P.S.8
Thompson, C.B.9
Mak, T.W.10
-
54
-
-
17144407983
-
Interferon-gamma acts directly on CD8+ T cells to increase their abundance during virus infection
-
Whitmire, J. K., J. T. Tan, and J. L. Whitton. 2005. Interferon-gamma acts directly on CD8+ T cells to increase their abundance during virus infection. J. Exp. Med. 201: 1053-1059.
-
(2005)
J. Exp. Med.
, vol.201
, pp. 1053-1059
-
-
Whitmire, J.K.1
Tan, J.T.2
Whitton, J.L.3
-
55
-
-
70349249977
-
Dynamics of peripheral tolerance and immune regulation mediated by Treg
-
Sakaguchi, S., K. Wing, and T. Yamaguchi. 2009. Dynamics of peripheral tolerance and immune regulation mediated by Treg. Eur. J. Immunol. 39: 2331-2336.
-
(2009)
Eur. J. Immunol.
, vol.39
, pp. 2331-2336
-
-
Sakaguchi, S.1
Wing, K.2
Yamaguchi, T.3
-
56
-
-
0038025292
-
Therapeutic use of IL-2 to enhance antiviral T-cell responses in vivo
-
Blattman, J. N., J. M. Grayson, E. J. Wherry, S. M. Kaech, K. A. Smith, and R. Ahmed. 2003. Therapeutic use of IL-2 to enhance antiviral T-cell responses in vivo. Nat. Med. 9: 540-547.
-
(2003)
Nat. Med.
, vol.9
, pp. 540-547
-
-
Blattman, J.N.1
Grayson, J.M.2
Wherry, E.J.3
Kaech, S.M.4
Smith, K.A.5
Ahmed, R.6
-
57
-
-
32544459770
-
Restoring function in exhausted CD8 T cells during chronic viral infection
-
Barber, D. L., E. J. Wherry, D. Masopust, B. Zhu, J. P. Allison, A. H. Sharpe, G. J. Freeman, and R. Ahmed. 2006. Restoring function in exhausted CD8 T cells during chronic viral infection. Nature 439: 682-687.
-
(2006)
Nature
, vol.439
, pp. 682-687
-
-
Barber, D.L.1
Wherry, E.J.2
Masopust, D.3
Zhu, B.4
Allison, J.P.5
Sharpe, A.H.6
Freeman, G.J.7
Ahmed, R.8
-
58
-
-
78049243425
-
Conditional regulatory T-cell depletion releases adaptive immunity preventing carcinogenesis and suppressing established tumor growth
-
Teng, M. W., S. F. Ngiow, B. Von Scheidt, N. McLaughlin, T. Sparwasser, and M. J. Smyth. 2010. Conditional regulatory T-cell depletion releases adaptive immunity preventing carcinogenesis and suppressing established tumor growth. Cancer Res. 70: 7800-7809.
-
(2010)
Cancer Res.
, vol.70
, pp. 7800-7809
-
-
Teng, M.W.1
Ngiow, S.F.2
Von Scheidt, B.3
McLaughlin, N.4
Sparwasser, T.5
Smyth, M.J.6
|