Ubiquitination by March-I prevents MHC class II recycling and promotes MHC class II turnover in antigen-presenting cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 33, 2015, Pages 10449-10454

  Cho, Kyung Jin ^a   Walseng, Even ^a   Ishido, Satoshi ^b   Roche, Paul A ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b SHOWA PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Antigen processing and presentation; March I; MHC class II; Recycling; Ubiquitination

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; UBIQUITIN PROTEIN LIGASE E3; UBIQUITIN PROTEIN LIGASE E3 MARCH I; UNCLASSIFIED DRUG; HLA ANTIGEN CLASS 2; LIPOPOLYSACCHARIDE; MARCH1 PROTEIN, MOUSE; PEPTIDE; UBIQUITIN; UBIQUITIN PROTEIN LIGASE;

ANIMAL CELL; ANTIGEN PRESENTING CELL; ARTICLE; B LYMPHOCYTE; BIOSYNTHESIS; CELL SURFACE; DENDRITIC CELL; ENDOCYTOSIS; INTERNALIZATION; LYSOSOME; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; PROTEIN TARGETING; TURNOVER TIME; UBIQUITINATION; ANIMAL; ANTIGEN PRESENTATION; C57BL MOUSE; CD4+ T LYMPHOCYTE; CHEMISTRY; CYTOLOGY; GENETICS; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY;

MUS;

ANIMALS; ANTIGEN PRESENTATION; ANTIGEN-PRESENTING CELLS; B-LYMPHOCYTES; CD4-POSITIVE T-LYMPHOCYTES; DENDRITIC CELLS; ENDOCYTOSIS; HISTOCOMPATIBILITY ANTIGENS CLASS II; LIPOPOLYSACCHARIDES; LYSOSOMES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PEPTIDES; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES;

EID: 84939811650     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1507981112     Document Type: Article

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