T cell sensing of antigen dose governs interactive behavior with dendritic cells and sets a threshold for T cell activation

Nature Immunology

Volumn 9, Issue 3, 2008, Pages 282-291

  Henrickson, Sarah E ^a   Mempel, Thorsten R ^a   Mazo, Irina B ^a   Liu, Bai ^b   Artyomov, Maxim N ^c   Zheng, Huan ^d   Peixoto, Antonio ^a   Flynn, Michael P ^a   Senman, Balimkiz ^a   Junt, Tobias ^a   Wong, Hing C ^b   Chakraborty, Arup K ^c,d   von Andrian, Ulrich H ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b Altor BioScience   (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^d Massachusetts Institute of Technology Cambridge   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN PRESENTING CELL; ARTICLE; CD8+ T LYMPHOCYTE; CELL DENSITY; CELL HOMING; CELL INTERACTION; CELLULAR IMMUNITY; CONTROLLED STUDY; CORRELATION ANALYSIS; DENDRITIC CELL; LYMPH NODE; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE HOMING; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN INDUCTION; T LYMPHOCYTE ACTIVATION;

ANIMALS; ANTIGEN-PRESENTING CELLS; ANTIGENS, SURFACE; CELLS, CULTURED; DENDRITIC CELLS; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; KINETICS; LYMPHOCYTE ACTIVATION; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; MICE; MICE, INBRED C57BL; PEPTIDE FRAGMENTS; T-LYMPHOCYTES;

EID: 39449094869     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni1559     Document Type: Article

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