Beyond CTLA-4 and PD-1, the generation Z of negative checkpoint regulators

Frontiers in Immunology

Volumn 6, Issue AUG, 2015, Pages

  Le Mercier, Isabelle ^a   Lines, J Louise ^a   Noelle, Randolph J ^a  

^a DARTMOUTH HITCHCOCK MEDICAL CENTER   (United States)

Author keywords

Autoimmunity; BTLA; Cancer immunotherapy; LAG 3; Negative checkpoint regulators; TIGIT; TIM 3; VISTA

Indexed keywords

CD8ALPHA ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; ECALECTIN; GAMMA INTERFERON; HIGH MOBILITY GROUP B1 PROTEIN; INTERLEUKIN 10; INTERLEUKIN 17; MEMBRANE PROTEIN; PROGRAMMED DEATH 1 RECEPTOR; T CELL IMMUNOGLOBULIN AND MUCIN DOMAIN CONTAINING PROTEIN 3; UNCLASSIFIED DRUG;

AUTOIMMUNITY; BACTERICIDAL ACTIVITY; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL CYCLE CHECKPOINT; CELL DIFFERENTIATION; CELL EXPANSION; CELL SURVIVAL; COXSACKIEVIRUS B3; CYTOTOXIC T LYMPHOCYTE; EXHAUSTION; GENE; GENE EXPRESSION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; IMMUNOTHERAPY; INFLAMMATION; INNATE IMMUNITY; LYMPHOCYTE ACTIVATED GENE 3; NATURAL KILLER CELL; NONHUMAN; PHOSPHORYLATION; REGULATORY T LYMPHOCYTE; REVIEW; T LYMPHOCYTE ACTIVATION; TH17 CELL; TH2 CELL; TUMOR IMMUNITY; TUMOR REGRESSION; UPREGULATION;

EID: 84941280057     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2015.00418     Document Type: Review

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