An Inhibitory Ig Superfamily Protein Expressed by Lymphocytes and APCs Is Also an Early Marker of Thymocyte Positive Selection

Journal of Immunology

Volumn 172, Issue 10, 2004, Pages 5931-5939

  Han, Peggy ^a   Goularte, Olivia D ^a   Rufner, Kevin ^a   Wilkinson, Beverley ^a   Kaye, Jonathan ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; IMMUNOGLOBULIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN PRESENTING CELL; ARTICLE; B AND T LYMPHOCYTE ATTENUATOR GENE; BTLA GENE; CONTROLLED STUDY; FLUORESCENCE MICROSCOPY; GENE; GENE EXPRESSION; LYMPHOCYTE DIFFERENTIATION; MOUSE; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T LYMPHOCYTE ACTIVATION; THYMOCYTE; TRANSGENIC MOUSE;

EID: 2442477456     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.172.10.5931     Document Type: Article

References (32)

1. Starr, T. K., S. C. Jameson, and K. A. Hogquist. 2003. Positive and negative selection of T cells. Annu. Rev. Immunol. 21:139.
2. Wilkinson, B., J. Y. Chen, P. Han, K. M. Rufner, O. D. Goularte, and J. Kaye. 2002. TOX: an HMO box protein implicated in the regulation of thymocyte selection. Nat. Immunol. 3:272.
3. Watanabe, N., M. Gavrieli, J. R. Sedy, J. Yang, F. Fallarino, S. K. Loftin, M. A. Hurchla, N. Zimmerman, J. Sim, X. Zang, et al. 2003. BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1. Nat. Immunol. 4:670.
4. + T cells in transgenic mice expressing a class II MHC-restricted antigen receptor. Nature 341:746.
5. Altschul, S. F., W. Gish, W. Miller, E. W. Myers, and D. J. Lipman. 1990. Basic local alignment search tool. J. Mol. Biol. 215:403.
6. Kaye, J., and D. L. Ellenberger. 1992. Differentiation of an immature T cell line: a model of thymic positive selection. Cell 71:423.
7. Kaye, J., and C. A. Janeway, Jr. 1984. The Fab fragment of a directly activating monoclonal antibody that precipitates a disulfide-linked heterodimer from a helper T cell clone blocks activation by either allogeneic Ia or antigen and self-Ia. J. Exp. Med. 159:1397.
8. Chen, Y., T. Maguire, and R. M. Marks. 1996. Demonstration of binding of dengue virus envelope protein to target cells. J. Virol. 70:8765.
9. Kishiro, Y., M. Kagawa, I. Nalto, and Y. Sado. 1995. A novel method of preparing rat-monoclonal antibody-producing hybridomas by using rat medial iliac lymph node cells. Cell Struct. Funct. 20:151.
10. Kilmartin, J. V., B. Wright, and C. Milstein. 1982. Rat monoclonal antitubulin antibodies derived by using a new nonsecreting rat cell line. J. Cell Biol. 93:576.
11. Lutz, M. B., N. Kukutsch, A. L. Ogilvie, S. Rossner, F. Koch, N. Romani, and G. Schuler. 1999. An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow. J. Immunol. Methods 223:77.
12. Alberola-Ila, J., and G. Hernandez-Hoyos. 2003. The Ras/MAPK cascade and the control of positive selection. Immunol. Rev. 191:79.
13. Raveteh, I. V., and L. L. Lanier. 2000. Immune inhibitory receptors. Science 290:84.
14. Sayos, J., C. Wu, M. Morra, N. Wang, X. Zhang, D. Allen, S. van Schaik, L. Notarangelo, R. Geha, M. G. Roncarolo, et al. 1998. The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM. Nature 395:462.
15. Poy, F., M. B. Yaffe, J. Sayos, K. Saxena, M. Morra, J. Sumegi, L. C. Cantley, C. Terhorst, and M. J. Eck. 1999. Crystal structures of the XLP protein SAP reveal a class of SH2 domains with extended, phosphotyrosine-independent sequence recognition. Mol. Cell 4:555.
16. + thymocytes. Eur. J. Immunol. 23:739.
17. D'Ambrosio, D., D. C. Fong, and J. C. Cambier. 1996. The SHIP phosphatase becomes associated with FcγRIIB1 and is tyrosine phosphorylated during 'negative' signaling. Immunol. Lett. 54:77.
18. Villalba, M., J. Hernandez, M. Deckert, Y. Tanaka, and A. Altman. 2000. Vav modulation of the Ras/MEK/ERK signaling pathway plays a role in NFAT activation and CD69 up-regulation. Eur. J. Immunol. 30:1587.
19. Blank, C., I. Brown, R. Marks, H. Nishimura, T. Honjo, and T. F. Gajewski. 2003. Absence of programmed death receptor 1 alters thymic development and enhances generation of CD4/CD8 double-negative TCR-transgenic T cells. J. Immunol. 171:4574.
20. + suppressor T cells: more questions than answers. Nat. Rev. Immunol. 2:389.
21. Lanier, L. L. 1998. NK cell receptors. Annu. Rev. Immunol. 16:359.
22. Bates, E. E., N. Fournier, E. Garcia, J. Valladeau, I. Durand, J. J. Pin, S. M. Zorawski, S. Patel, J. S. Abrams, S. Lebecque, et al. 1999. APCs express DCIR, a novel C-type lectin surface receptor containing an immunoreceptor tyrosine-based inhibitory motif. J. Immunol. 163:1973.
23. Huang, X., Z. Yuan, G. Chen, M. Zhang, W. Zhang, Y. Yu, and X. Cao. 2001. Cloning and characterization of a novel ITIM containing lectin-like immunoreceptor LLIR and its two transmembrane region deletion variants. Biochem. Biophys. Res. Commun. 281:131.
24. Fournier, N., L. Chalus, I. Durand, E. Garcia, J. J. Pin, T. Churakova, S. Patel, C. Zlot, D. Gorman, S. Zurawski, et al. 2000. FDF03, a novel inhibitory receptor of the immunoglobulin superfamily, is expressed by human dendritic and myeloid cells. J. Immunol. 165:1197.
25. Sinclair, N. R. 1999. Why so many coinhibitory receptors? Scand J. Immunol. 50:10.
26. Vieites, J. M., R. de la Torre, M. A. Ortega, T. Montero, J. M. Peco, A. Sanchez-Pozo, A. Gil, and A. Suarez. 2003. Characterization of human cd200 glycoprotein receptor gene located on chromosome 3q12-13. Gene 311:99.
27. Wright, G. J., M. J. Puklavec, A. C. Willis, R. M. Hoek, J. D. Sedgwick, M. H. Brown, and A. N. Barclay. 2000. Lymphoid/Neuronal cell surface OX2 glycoprotein recognizes a novel receptor on macrophages implicated in the control of their function. Immunity 13:233.
28. Wright, G. J., H. Cherwinski, M. Foster-Cuevas, G. Brooke, M. J. Puklavec, M. Bigler, Y. Song, M. Jemalm, D. Gorman, T. McClanahan, et al. 2003. Characterization of the CD200 receptor family in mice and humans and their interactions with CD200. J. Immunol. 171:3034.
29. Barclay, A. N., M. J. Clark, and G. W. McCaughan. 1986. Neuronal/ Lymphoid membrane glycoprotein MRC OX-2 is a member of the immunoglobulin superfamily with a light-chain-like structure. Biochem. Soc. Symp. 51:149.
30. Wright, G. J., M. Jones, M. J. Puklavec, M. H. Brown, and A. N. Barclay. 2001. The unusual distribution of the neuronal/lymphoid cell surface CD200 (OX2) glycoprotein is conserved in humans. Immunology 102:173.
31. Hoek, R. M., S. R. Ruuls, C. A. Murphy, G. J. Wright, R. Goddard, S. M. Zorawski, B. Blom, M. E. Homola, W. J. Streit, M. H. Brown, et al. 2000. Down-regulation of the macrophage lineage through interaction with OX2 (CD200). Science 290:1768.
32. Nathan, C., and W. A. Muller. 2001. Putting the brakes on innate immunity: a regulatory role for CD200? Nat. Immunol. 2:17.