-
1
-
-
0037810670
-
BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1
-
Watanabe, N., M. Gavrieli, J. R. Sedy, J. Yang, F. Fallarino, S. K. Loftin, M. A. Hurchla, N. Zimmerman, J. Sim, X. Zang, et al. 2003. BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1. Nat. Immunol. 4: 670-679.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 670-679
-
-
Watanabe, N.1
Gavrieli, M.2
Sedy, J.R.3
Yang, J.4
Fallarino, F.5
Loftin, S.K.6
Hurchla, M.A.7
Zimmerman, N.8
Sim, J.9
Zang, X.10
-
2
-
-
19544383401
-
The evolving crosstalk between co-stimulatory and co-inhibitory receptors: HVEM-BTLA
-
DOI 10.1016/j.it.2005.03.010, PII S1471490605000815
-
Croft, M. 2005. The evolving crosstalk between co-stimulatory and co-inhibitory receptors: HVEM-BTLA. Trends Immunol. 26: 292-294. (Pubitemid 40732659)
-
(2005)
Trends in Immunology
, vol.26
, Issue.6
, pp. 292-294
-
-
Croft, M.1
-
3
-
-
19944433635
-
B and T lymphocyte attenuator regulates T cell activation through interaction with herpesvirus entry mediator
-
DOI 10.1038/ni1144
-
Sedy, J. R., M. Gavrieli, K. G. Potter, M. A. Hurchla, R. C. Lindsley, K. Hildner, S. Scheu, K. Pfeffer, C. F. Ware, T. L. Murphy, and K. M. Murphy. 2005. B and T lymphocyte attenuator regulates T cell activation through interaction with herpesvirus entry mediator. Nat. Immunol. 6: 90-98. (Pubitemid 40136700)
-
(2005)
Nature Immunology
, vol.6
, Issue.1
, pp. 90-98
-
-
Sedy, J.R.1
Gavrieli, M.2
Potter, K.G.3
Hurchla, M.A.4
Lindsley, R.C.5
Hildner, K.6
Scheu, S.7
Pfeffer, K.8
Ware, C.F.9
Murphy, T.L.10
Murphy, K.M.11
-
4
-
-
2442477456
-
An Inhibitory Ig Superfamily Protein Expressed by Lymphocytes and APCs Is Also an Early Marker of Thymocyte Positive Selection
-
Han, P., O. D. Goularte, K. Rufner, B. Wilkinson, and J. Kaye. 2004. An inhibitory Ig superfamily protein expressed by lymphocytes and APCs is also an early marker of thymocyte positive selection. J. Immunol. 172: 5931-5939. (Pubitemid 38621192)
-
(2004)
Journal of Immunology
, vol.172
, Issue.10
, pp. 5931-5939
-
-
Han, P.1
Goularte, O.D.2
Rufner, K.3
Wilkinson, B.4
Kaye, J.5
-
5
-
-
12844268068
-
A coreceptor interaction between the CD28 and TNF receptor family members B and T lymphocyte attenuator and herpesvirus entry mediator
-
Gonzalez, L. C., K. M. Loyet, J. Calemine-Fenaux, V. Chauhan, B. Wranik, W. Ouyang, and D. L. Eaton. 2005. A coreceptor interaction between the CD28 and TNF receptor family members B and T lymphocyte attenuator and herpesvirus entry mediator. Proc. Natl. Acad. Sci. USA 102: 1116-1121.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 1116-1121
-
-
Gonzalez, L.C.1
Loyet, K.M.2
Calemine-Fenaux, J.3
Chauhan, V.4
Wranik, B.5
Ouyang, W.6
Eaton, D.L.7
-
6
-
-
33748088535
-
Balancing co-stimulation and inhibition with BTLA and HVEM
-
DOI 10.1038/nri1917, PII NRI1917
-
Murphy, K. M., C. A. Nelson, and J. R. Sedy. 2006. Balancing co-stimulation and inhibition with BTLA and HVEM. Nat. Rev. Immunol. 6: 671-681. (Pubitemid 44298216)
-
(2006)
Nature Reviews Immunology
, vol.6
, Issue.9
, pp. 671-681
-
-
Murphy, K.M.1
Nelson, C.A.2
Sedy, J.R.3
-
7
-
-
0344495270
-
Characterization of phosphotyrosine binding motifs in the cytoplasmic domain of B and T lymphocyte attenuator required for association with protein tyrosine phosphatases SHP-1 and SHP-2
-
DOI 10.1016/j.bbrc.2003.11.070
-
Gavrieli, M., N. Watanabe, S. K. Loftin, T. L. Murphy, and K. M. Murphy. 2003. Characterization of phosphotyrosine binding motifs in the cytoplasmic domain of B and T lymphocyte attenuator required for association with protein tyrosine phosphatases SHP-1 and SHP-2. Biochem. Biophys. Res. Commun. 312: 1236-1243. (Pubitemid 37490949)
-
(2003)
Biochemical and Biophysical Research Communications
, vol.312
, Issue.4
, pp. 1236-1243
-
-
Gavrieli, M.1
Watanabe, N.2
Loftin, S.K.3
Murphy, T.L.4
Murphy, K.M.5
-
8
-
-
38949214015
-
Targeting of antigen to the herpesvirus entry mediator augments primary adaptive immune responses
-
Lasaro, M. O., N. Tatsis, S. E. Hensley, J. C. Whitbeck, S. W. Lin, J. J. Rux, E. J. Wherry, G. H. Cohen, R. J. Eisenberg, and H. C. Ertl. 2008. Targeting of antigen to the herpesvirus entry mediator augments primary adaptive immune responses. Nat. Med. 14: 205-212.
-
(2008)
Nat. Med.
, vol.14
, pp. 205-212
-
-
Lasaro, M.O.1
Tatsis, N.2
Hensley, S.E.3
Whitbeck, J.C.4
Lin, S.W.5
Rux, J.J.6
Wherry, E.J.7
Cohen, G.H.8
Eisenberg, R.J.9
Ertl, H.C.10
-
9
-
-
33845232099
-
HSP70 gene fused with Hantavirus S segment DNA significantly enhances the DNA vaccine potency against hantaviral nucleocapsid protein in vivo
-
DOI 10.1016/j.vaccine.2006.07.040, PII S0264410X06009030
-
Li, J., Z. X. Ye, K. N. Li, J. H. Cui, J. Li, Y. X. Cao, Y. F. Liu, and S. J. Yang. 2007. HSP70 gene fused with Hantavirus S segment DNA significantly enhances the DNA vaccine potency against hantaviral nucleocapsid protein in vivo. Vaccine 25: 239-252. (Pubitemid 44856081)
-
(2007)
Vaccine
, vol.25
, Issue.2
, pp. 239-252
-
-
Li, J.1
Ye, Z.X.2
Li, K.N.3
Cui, J.H.4
Li, J.5
Cao, Y.X.6
Liu, Y.F.7
Yang, S.J.8
-
10
-
-
34247611546
-
A DNA vaccine against chimeric AFP enhanced by HSP70 suppresses growth of hepatocellular carcinoma
-
Lan, Y. H., Y. G. Li, Z. W. Liang, M. Chen, M. L. Peng, L. Tang, H. D. Hu, and H. Ren. 2007. A DNA vaccine against chimeric AFP enhanced by HSP70 suppresses growth of hepatocellular carcinoma. Cancer Immunol. Immunother. 56: 1009-1016.
-
(2007)
Cancer Immunol. Immunother.
, vol.56
, pp. 1009-1016
-
-
Lan, Y.H.1
Li, Y.G.2
Liang, Z.W.3
Chen, M.4
Peng, M.L.5
Tang, L.6
Hu, H.D.7
Ren, H.8
-
11
-
-
33845808853
-
An hsp70 fusion protein vaccine potentiates the immune response against Japanese encephalitis virus
-
DOI 10.1007/s00705-006-0822-z
-
Ge, F. F., Y. F. Qiu, Y. W. Yang, and P. Y. Chen. 2007. An hsp70 fusion protein vaccine potentiates the immune response against Japanese encephalitis virus. Arch. Virol. 152: 125-135. (Pubitemid 44974620)
-
(2007)
Archives of Virology
, vol.152
, Issue.1
, pp. 125-135
-
-
Ge, F.-F.1
Qiu, Y.-F.2
Yang, Y.-W.3
Chen, P.-Y.4
-
12
-
-
40449086741
-
Structural determinants of herpesvirus entry mediator recognition by murine B and T lymphocyte attenuator
-
Nelson, C. A., M. D. Fremont, J. R. Sedy, P. S. Norris, C. F. Ware, K. M. Murphy, and D. H. Fremont. 2008. Structural determinants of herpesvirus entry mediator recognition by murine B and T lymphocyte attenuator. J. Immunol. 180: 940-947.
-
(2008)
J. Immunol.
, vol.180
, pp. 940-947
-
-
Nelson, C.A.1
Fremont, M.D.2
Sedy, J.R.3
Norris, P.S.4
Ware, C.F.5
Murphy, K.M.6
Fremont, D.H.7
-
13
-
-
31144474853
-
Soluble form of T cell Ig mucin 3 is an inhibitory molecule in T cell-mediated immune response
-
Geng, H., G. M. Zhang, D. Li, H. Zhang, Y. Yuan, H. G. Zhu, H. Xiao, L. F. Han, and Z. H. Feng. 2006. Soluble form of T cell Ig mucin 3 is an inhibitory molecule in T cell-mediated immune response. J. Immunol. 176: 1411-1420. (Pubitemid 43134283)
-
(2006)
Journal of Immunology
, vol.176
, Issue.3
, pp. 1411-1420
-
-
Geng, H.1
Zhang, G.-M.2
Li, D.3
Zhang, H.4
Yuan, Y.5
Zhu, H.-G.6
Xiao, H.7
Han, L.-F.8
Feng, Z.-H.9
-
14
-
-
6344240464
-
Blocking programmed death-1 ligand-PD-1 interactions by local gene therapy results in enhancement of antitumor effect of secondary lymphoid tissue chemokine
-
He, Y. F., G. M. Zhang, X. H. Wang, H. Zhang, Y. Yuan, D. Li, and Z. H. Feng. 2004. Blocking programmed death-1 ligand-PD-1 interactions by local gene therapy results in enhancement of antitumor effect of secondary lymphoid tissue chemokine. J. Immunol. 173: 4919-4928.
-
(2004)
J. Immunol.
, vol.173
, pp. 4919-4928
-
-
He, Y.F.1
Zhang, G.M.2
Wang, X.H.3
Zhang, H.4
Yuan, Y.5
Li, D.6
Feng, Z.H.7
-
15
-
-
33646345848
-
HSP70 vaccine in combination with gene therapy with plasmid DNA encoding sPD-1 overcomes immune resistance and suppresses the progression of pulmonary metastatic melanoma
-
DOI 10.1002/ijc.21795
-
Geng, H., G. M. Zhang, H. Xiao, Y. Yuan, D. Li, H. Zhang, H. Qiu, Y. F. He, and Z. H. Feng. 2006. HSP70 vaccine in combination with gene therapy with plasmid DNA encoding sPD-1 overcomes immune resistance and suppresses the progression of pulmonary metastatic melanoma. Int. J. Cancer 118: 2657-2664. (Pubitemid 43673341)
-
(2006)
International Journal of Cancer
, vol.118
, Issue.11
, pp. 2657-2664
-
-
Geng, H.1
Zhang, G.-M.2
Xiao, H.3
Yuan, Y.4
Li, P.5
Zhang, H.6
Qiu, H.7
He, Y.-F.8
Feng, Z.-H.9
-
16
-
-
34250156711
-
Soluble PD-1 facilitates 4-1BBL - Triggered antitumor immunity against murine H22 hepatocarcinoma in vivo
-
DOI 10.1158/1078-0432.CCR-06-2154
-
Xiao, H., B. Huang, Y. Yuan, D. Li, L. F. Han, Y. Liu, W. Gong, F. H. Wu, G. M. Zhang, and Z. H. Feng. 2007. Soluble PD-1 facilitates 4-1BBL-triggered antitumor immunity against murine H22 hepatocarcinoma in vivo. Clin. Cancer Res. 13: 1823-1830. (Pubitemid 46952952)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.6
, pp. 1823-1830
-
-
Xiao, H.1
Huang, B.2
Yuan, Y.3
Li, D.4
Han, L.-F.5
Liu, Y.6
Gong, W.7
Wu, F.-H.8
Zhang, G.-M.9
Feng, Z.-H.10
-
17
-
-
38849171171
-
The inhibitory HVEM-BTLA pathway counter regulates lymphotoxin receptor signaling to achieve homeostasis of dendritic cells
-
De Trez, C., K. Schneider, K. Potter, N. Droin, J. Fulton, P. S. Norris, S. W. Ha, Y. X. Fu, T. Murphy, K. M. Murphy, et al. 2008. The inhibitory HVEM-BTLA pathway counter regulates lymphotoxin receptor signaling to achieve homeostasis of dendritic cells. J. Immunol. 180: 238-248.
-
(2008)
J. Immunol.
, vol.180
, pp. 238-248
-
-
De Trez, C.1
Schneider, K.2
Potter, K.3
Droin, N.4
Fulton, J.5
Norris, P.S.6
Ha, S.W.7
Fu, Y.X.8
Murphy, T.9
Murphy, K.M.10
-
18
-
-
44749084289
-
The TNF receptor and Ig superfamily members form an integrated signaling circuit controlling dendritic cell homeostasis
-
De Trez, C., and C. F. Ware. 2008. The TNF receptor and Ig superfamily members form an integrated signaling circuit controlling dendritic cell homeostasis. Cytokine Growth Factor Rev. 19: 277-284.
-
(2008)
Cytokine Growth Factor Rev.
, vol.19
, pp. 277-284
-
-
De Trez, C.1
Ware, C.F.2
-
20
-
-
35448936377
-
Adoptively transferred tumor-specific T cells stimulated ex vivo using herpes simplex virus amplicons encoding 4-1BBL persist in the host and show antitumor activity in vivo
-
Yi, K. H., H. Nechushtan, W. J. Bowers, G. R. Walker, Y. Zhang, D. G. Pham, E. R. Podack, H. J. Federoff, K. A. Tolba, and J. D. Rosenblatt. 2007. Adoptively transferred tumor-specific T cells stimulated ex vivo using herpes simplex virus amplicons encoding 4-1BBL persist in the host and show antitumor activity in vivo. Cancer Res. 67: 10027-10037.
-
(2007)
Cancer Res.
, vol.67
, pp. 10027-10037
-
-
Yi, K.H.1
Nechushtan, H.2
Bowers, W.J.3
Walker, G.R.4
Zhang, Y.5
Pham, D.G.6
Podack, E.R.7
Federoff, H.J.8
Tolba, K.A.9
Rosenblatt, J.D.10
-
21
-
-
36849021712
-
T cell-encoded CD80 and 4-1BBL induce autoand transcostimulation, resulting in potent tumor rejection
-
Stephan, M. T., V. Ponomarev, R. J. Brentjens, A. H. Chang, K. V. Dobrenkov, G. Heller, and M. Sadelain. 2007. T cell-encoded CD80 and 4-1BBL induce autoand transcostimulation, resulting in potent tumor rejection. Nat. Med. 13: 1440-1449.
-
(2007)
Nat. Med.
, vol.13
, pp. 1440-1449
-
-
Stephan, M.T.1
Ponomarev, V.2
Brentjens, R.J.3
Chang, A.H.4
Dobrenkov, K.V.5
Heller, G.6
Sadelain, M.7
-
22
-
-
42449147063
-
PD-1-PD-1 ligand interaction contributes to immunosuppressive microenvironment of Hodgkin lymphoma
-
Yamamoto, R., M. Nishikori, T. Kitawaki, T. Sakai, M. Hishizawa, M. Tashima, T. Kondo, K. Ohmori, M. Kurata, T. Hayashi, and T. Uchiyama. 2008. PD-1-PD-1 ligand interaction contributes to immunosuppressive microenvironment of Hodgkin lymphoma. Blood 111: 3220-3224.
-
(2008)
Blood
, vol.111
, pp. 3220-3224
-
-
Yamamoto, R.1
Nishikori, M.2
Kitawaki, T.3
Sakai, T.4
Hishizawa, M.5
Tashima, M.6
Kondo, T.7
Ohmori, K.8
Kurata, M.9
Hayashi, T.10
Uchiyama, T.11
-
23
-
-
55649120647
-
Protective effect of a RSV subunit vaccine candidate G1F/M2 was enhanced by a HSP70-like protein in mice
-
Zeng, R., Z. Zhang, X. Mei, W. Gong, and L. Wei. 2008. Protective effect of a RSV subunit vaccine candidate G1F/M2 was enhanced by a HSP70-like protein in mice. Biochem. Biophys. Res. Commun. 377: 495-499.
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.377
, pp. 495-499
-
-
Zeng, R.1
Zhang, Z.2
Mei, X.3
Gong, W.4
Wei, L.5
-
24
-
-
42249115712
-
Combination of vascular endothelial growth factor receptor/platelet- derived growth factor receptor inhibition markedly improves radiation tumor therapy
-
DOI 10.1158/1078-0432.CCR-07-1893
-
Timke, C., H. Zieher, A. Roth, K. Hauser, K. E. Lipson, K. J. Weber, J. Debus, A. Abdollahi, and P. E. Huber. 2008. Combination of vascular endothelial growth factor receptor/platelet-derived growth factor receptor inhibition markedly improves radiation tumor therapy. Clin. Cancer Res. 14: 2210-2219. (Pubitemid 351551134)
-
(2008)
Clinical Cancer Research
, vol.14
, Issue.7
, pp. 2210-2219
-
-
Timke, C.1
Zieher, H.2
Roth, A.3
Hauser, K.4
Lipson, K.E.5
Weber, K.J.6
Debus, J.7
Abdollahi, A.8
Huber, P.E.9
-
25
-
-
37549048034
-
+ T cells after intratumoral Ad5-TRAIL/CpG oligodeoxynucleotide combination therapy
-
+ T cells after intratumoral Ad5-TRAIL/CpG oligodeoxynucleotide combination therapy. Cancer Res. 67: 11980-11990.
-
(2007)
Cancer Res.
, vol.67
, pp. 11980-11990
-
-
VanOosten, R.L.1
Griffith, T.S.2
-
26
-
-
33846559124
-
Combination angiostatic therapy completely inhibits ocular and tumor angiogenesis
-
Dorrell, M. I., E. Aguilar, L. Scheppke, F. H. Barnett, and M. Friedlander. 2007. Combination angiostatic therapy completely inhibits ocular and tumor angiogenesis. Proc. Natl. Acad. Sci. USA 104: 967-972.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 967-972
-
-
Dorrell, M.I.1
Aguilar, E.2
Scheppke, L.3
Barnett, F.H.4
Friedlander, M.5
-
27
-
-
34347255017
-
A combination hybrid-based vaccination/adoptive cellular therapy to prevent tumor growth by involvement of T cells
-
DOI 10.1158/0008-5472.CAN-06-3677
-
Savai, R., R. T. Schermuly, S. S. Pullamsetti, M. Schneider, S. Greschus, H. A. Ghofrani, H. Traupe, F. Grimminger, and G. A. Banat. 2007. A combination hybrid-based vaccination/adoptive cellular therapy to prevent tumor growth by involvement of T cells. Cancer Res. 67: 5443-5453. (Pubitemid 46997285)
-
(2007)
Cancer Research
, vol.67
, Issue.11
, pp. 5443-5453
-
-
Savai, R.1
Schermuly, R.T.2
Pullamsetti, S.S.3
Schneider, M.4
Greschus, S.5
Ghofrani, H.A.6
Traupe, H.7
Grimminger, F.8
Banat, G.-A.9
-
28
-
-
34548654412
-
Efficient cross-presentation by heat shock protein 90-peptide complex-loaded dendritic cells via an endosomal pathway
-
Kurotaki, T., Y. Tamura, G. Ueda, J. Oura, G. Kutomi, Y. Hirohashi, H. Sahara, T. Torigoe, H. Hiratsuka, H. Sunakawa, et al. 2007. Efficient cross-presentation by heat shock protein 90-peptide complex-loaded dendritic cells via an endosomal pathway. J. Immunol. 179: 1803-1813.
-
(2007)
J. Immunol.
, vol.179
, pp. 1803-1813
-
-
Kurotaki, T.1
Tamura, Y.2
Ueda, G.3
Oura, J.4
Kutomi, G.5
Hirohashi, Y.6
Sahara, H.7
Torigoe, T.8
Hiratsuka, H.9
Sunakawa, H.10
-
29
-
-
33750359212
-
Enhanced immunogenicity of heat shock protein 70 peptide complexes from dendritic cell-tumor fusion cells
-
Enomoto, Y., A. Bharti, A. A. Khaleque, B. Song, C. Liu, V. Apostolopoulos, P. X. Xing, S. K. Calderwood, and J. Gong. 2006. Enhanced immunogenicity of heat shock protein 70 peptide complexes from dendritic cell-tumor fusion cells. J. Immunol. 177: 5946-5955. (Pubitemid 44628808)
-
(2006)
Journal of Immunology
, vol.177
, Issue.9
, pp. 5946-5955
-
-
Enomoto, Y.1
Bharti, A.2
Khaleque, A.A.3
Song, B.4
Liu, C.5
Apostolopoulos, V.6
Xing, P.-X.7
Calderwood, S.K.8
Gong, J.9
-
30
-
-
0036214288
-
Interaction of heat shock proteins with peptides and antigen presenting cells: Chaperoning of the innate and adaptive immune responses
-
DOI 10.1146/annurev.immunol.20.100301.064801
-
Srivastava, P. 2002. Interaction of heat shock proteins with peptides and antigen presenting cells: chaperoning of the innate and adaptive immune responses. Annu. Rev. Immunol. 20: 395-425. (Pubitemid 34293430)
-
(2002)
Annual Review of Immunology
, vol.20
, pp. 395-425
-
-
Srivastava, P.1
-
31
-
-
0037670279
-
Overcoming immune tolerance to cancer by heat shock protein vaccines
-
Liu, B., A. M. DeFilippo, and Z. Li. 2002. Overcoming immune tolerance to cancer by heat shock protein vaccines. Mol. Cancer Ther. 1: 1147-1151.
-
(2002)
Mol. Cancer Ther.
, vol.1
, pp. 1147-1151
-
-
Liu, B.1
DeFilippo, A.M.2
Li, Z.3
-
32
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor Foxp3
-
DOI 10.1126/science.1079490
-
Hori, S., T. Nomura, and S. Sakaguchi. 2003. Control of regulatory T cell development by the transcription factor Foxp3. Science 299: 1057-1061. (Pubitemid 36222930)
-
(2003)
Science
, vol.299
, Issue.5609
, pp. 1057-1061
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
33
-
-
34247271308
-
Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3
-
Williams, L. M., and A. Y. Rudensky. 2007. Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3. Nat. Immunol. 8: 277-284.
-
(2007)
Nat. Immunol.
, vol.8
, pp. 277-284
-
-
Williams, L.M.1
Rudensky, A.Y.2
-
35
-
-
45549097535
-
Regulatory T cell expression of herpesvirus entry mediator suppresses the function of B and T lymphocyte attenuator-positive effector T cells
-
Tao, R., L. Wang, K. M. Murphy, C. C. Fraser, and W. W. Hancock. 2008. Regulatory T cell expression of herpesvirus entry mediator suppresses the function of B and T lymphocyte attenuator-positive effector T cells. J. Immunol. 180: 6649-6655.
-
(2008)
J. Immunol.
, vol.180
, pp. 6649-6655
-
-
Tao, R.1
Wang, L.2
Murphy, K.M.3
Fraser, C.C.4
Hancock, W.W.5
-
36
-
-
38349094788
-
+ T cells
-
+ T cells. Nat. Immunol. 9: 122-124.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 122-124
-
-
Kaye, J.1
|