-
5
-
-
49249089425
-
Control of peripheral T-cell tolerance and autoimmunity via the CTLA-4 and PD-1 pathways
-
Fife BT, Bluestone JA (2008) Control of peripheral T-cell tolerance and autoimmunity via the CTLA-4 and PD-1 pathways. Immunol Rev 224:166-182.
-
(2008)
Immunol Rev
, vol.224
, pp. 166-182
-
-
Fife, B.T.1
Bluestone, J.A.2
-
6
-
-
14944359411
-
Consensual immunity: Success-driven development of T-helper-1 and T-helper-2 responses
-
DOI 10.1038/nri1569
-
Kalinski P, Moser M (2005) Consensual immunity: Success-driven development of T-helper-1 and T-helper-2 responses. Nat Rev Immunol 5:251-260. (Pubitemid 40364826)
-
(2005)
Nature Reviews Immunology
, vol.5
, Issue.3
, pp. 251-260
-
-
Kalinski, P.1
Moser, M.2
-
7
-
-
37349040852
-
+ T cells
-
+ T cells. Nat Immunol 9:34-41.
-
(2008)
Nat Immunol
, vol.9
, pp. 34-41
-
-
Kano, S.1
-
8
-
-
42649115767
-
TH17 cells in development: An updated view of their molecular identity and genetic programming
-
Dong C (2008) TH17 cells in development: An updated view of their molecular identity and genetic programming. Nat Rev Immunol 8:337-348.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 337-348
-
-
Dong, C.1
-
9
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor Foxp3
-
DOI 10.1126/science.1079490
-
Hori S, Nomura T, Sakaguchi S (2003) Control of regulatory T cell development by the transcription factor Foxp3. Science 299:1057-1061. (Pubitemid 36222930)
-
(2003)
Science
, vol.299
, Issue.5609
, pp. 1057-1061
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
10
-
-
34547749066
-
Emerging challenges in regulatory T cell function and biology
-
DOI 10.1126/science.1142331
-
Sakaguchi S, Powrie F (2007) Emerging challenges in regulatory T cell function and biology. Science 317:627-629. (Pubitemid 47229955)
-
(2007)
Science
, vol.317
, Issue.5838
, pp. 627-629
-
-
Sakaguchi, S.1
Powrie, F.2
-
11
-
-
0035162560
-
Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
-
Brunkow ME, et al. (2001) Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse. Nat Genet 27:68-73.
-
(2001)
Nat Genet
, vol.27
, pp. 68-73
-
-
Brunkow, M.E.1
-
12
-
-
0037383758
-
Aire regulates negative selection of organ-specific T cells
-
DOI 10.1038/ni906
-
Liston A, Lesage S, Wilson J, Peltonen L, Goodnow CC (2003) Aire regulates negative selection of organ-specific T cells. Nat Immunol 4:350-354. (Pubitemid 36432317)
-
(2003)
Nature Immunology
, vol.4
, Issue.4
, pp. 350-354
-
-
Liston, A.1
Lesage, S.2
Wilson, J.3
Peltonen, L.4
Goodnow, C.C.5
-
13
-
-
23844558032
-
The cellular mechanism of Aire control of T cell tolerance
-
DOI 10.1016/j.immuni.2005.07.005, PII S1074761305002372
-
Anderson MS, et al. (2005) The cellular mechanism of Aire control of T cell tolerance. Immunity 23:227-239. (Pubitemid 41169291)
-
(2005)
Immunity
, vol.23
, Issue.2
, pp. 227-239
-
-
Anderson, M.S.1
Venanzi, E.S.2
Chen, Z.3
Berzins, S.P.4
Benoist, C.5
Mathis, D.6
-
14
-
-
0030704726
-
+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
-
+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature 389:737-742.
-
(1997)
Nature
, vol.389
, pp. 737-742
-
-
Groux, H.1
-
15
-
-
0037018104
-
+ T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)-and Th2-inducing cytokines
-
+ T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)-and Th2-inducing cytokines. J Exp Med 195:603-616.
-
(2002)
J Exp Med
, vol.195
, pp. 603-616
-
-
Barrat, F.J.1
-
16
-
-
32644471889
-
Tr1 cells: From discovery to their clinical application
-
DOI 10.1016/j.smim.2006.01.007, PII S104453230600008X, Regulatory T Cells
-
Battaglia M, Gregori S, Bacchetta R, Roncarolo MG (2006) Tr1 cells: From discovery to their clinical application. Semin Immunol 18:120-127. (Pubitemid 43248740)
-
(2006)
Seminars in Immunology
, vol.18
, Issue.2
, pp. 120-127
-
-
Battaglia, M.1
Gregori, S.2
Bacchetta, R.3
Roncarolo, M.-G.4
-
17
-
-
34547214205
-
Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans
-
Roncarolo MG, Battaglia M (2007) Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans. Nat Rev Immunol 7:585-598.
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 585-598
-
-
Roncarolo, M.G.1
Battaglia, M.2
-
19
-
-
4644285392
-
E3 ubiquitin ligases as T cell anergy factors
-
DOI 10.1038/ni1106
-
Mueller DL (2004) E3 ubiquitin ligases as T cell anergy factors. Nat Immunol 5:883-890. (Pubitemid 39276232)
-
(2004)
Nature Immunology
, vol.5
, Issue.9
, pp. 883-890
-
-
Mueller, D.L.1
-
20
-
-
12144290293
-
Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins
-
DOI 10.1038/ni1047
-
Heissmeyer V, et al. (2004) Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins. Nat Immunol 5:255-265. (Pubitemid 38332122)
-
(2004)
Nature Immunology
, vol.5
, Issue.3
, pp. 255-265
-
-
Heissmeyer, V.1
Macian, F.2
Im, S.-H.3
Varma, R.4
Feske, S.5
Venuprasad, K.6
Gu, H.7
Liu, Y.-C.8
Dustin, M.L.9
Rao, A.10
-
21
-
-
18244375249
-
Egr-2 and Egr-3 are negative regulators of T cell activation
-
DOI 10.1038/ni1193
-
Safford M, et al. (2005) Egr-2 and Egr-3 are negative regulators of T cell activation. Nat Immunol 6:472-480. (Pubitemid 41716760)
-
(2005)
Nature Immunology
, vol.6
, Issue.5
, pp. 472-480
-
-
Safford, M.1
Collins, S.2
Lutz, M.A.3
Allen, A.4
Huang, C.-T.5
Kowalski, J.6
Blackford, A.7
Horton, M.R.8
Drake, C.9
Schwartz, R.H.10
Powell, J.D.11
-
22
-
-
0027984497
-
Krox-20 controls myelination in the peripheral nervous system
-
DOI 10.1038/371796a0
-
Topilko P, et al. (1994) Krox-20 controls myelination in the peripheral nervous system. Nature 371:796-799. (Pubitemid 24333867)
-
(1994)
Nature
, vol.371
, Issue.6500
, pp. 796-799
-
-
Topilko, P.1
Schneider-Maunoury, S.2
Levi, G.3
Baron-Van Evercooren, A.4
Younes Chennoufi, A.B.5
Seitanidou, T.6
Babinet, C.7
Charnay, P.8
-
23
-
-
0038068048
-
The CD4-related molecule, LAG-3 (CD223), regulates the expansion of activated T cells
-
Workman CJ, Vignali DA (2003) The CD4-related molecule, LAG-3 (CD223), regulates the expansion of activated T cells. Eur J Immunol 33:970-979.
-
(2003)
Eur J Immunol
, vol.33
, pp. 970-979
-
-
Workman, C.J.1
Vignali, D.A.2
-
24
-
-
2142815854
-
Lymphocyte activation gene-3 (CD223) regulates the size of the expanding T cell population following antigen activation in vivo
-
Workman CJ, et al. (2004) Lymphocyte activation gene-3 (CD223) regulates the size of the expanding T cell population following antigen activation in vivo. J Immunol 172:5450-5455.
-
(2004)
J Immunol
, vol.172
, pp. 5450-5455
-
-
Workman, C.J.1
-
25
-
-
5644263642
-
Role of LAG-3 in regulatory T cells
-
Huang CT, et al. (2004) Role of LAG-3 in regulatory T cells. Immunity 21:503-513.
-
(2004)
Immunity
, vol.21
, pp. 503-513
-
-
Huang, C.T.1
-
26
-
-
0036686408
-
Phenotypic analysis of the murine CD4-related glycoprotein, CD223 (LAG-3)
-
DOI 10.1002/1521-4141(200208)32:8<2255::AID-IMMU2255>3.0.CO;2-A
-
Workman CJ, Rice DS, Dugger KJ, Kurschner C, Vignali DA (2002) Phenotypic analysis of the murine CD4-related glycoprotein, CD223 (LAG-3). Eur J Immunol 32:2255-2263. (Pubitemid 34965888)
-
(2002)
European Journal of Immunology
, vol.32
, Issue.8
, pp. 2255-2263
-
-
Workman, C.J.1
Rice, D.S.2
Dugger, K.J.3
Kurschner, C.4
Vignali, D.A.A.5
-
28
-
-
33744990181
-
+ T cells
-
+ T cells. Nat Med 12:627-635.
-
(2006)
Nat Med
, vol.12
, pp. 627-635
-
-
Ochi, H.1
-
29
-
-
10344239897
-
+ T cells
-
+ T cells. J Immunol 173:7331-7338.
-
(2004)
J Immunol
, vol.173
, pp. 7331-7338
-
-
Harris, J.E.1
-
30
-
-
3242805018
-
Nucleosome-specific regulatory T cells engineered by triple gene transfer suppress a systemic autoimmune disease
-
Fujio K, et al. (2004) Nucleosome-specific regulatory T cells engineered by triple gene transfer suppress a systemic autoimmune disease. J Immunol 173:2118-2125. (Pubitemid 38971650)
-
(2004)
Journal of Immunology
, vol.173
, Issue.3
, pp. 2118-2125
-
-
Fujio, K.1
Okamoto, A.2
Tahara, H.3
Abe, M.4
Jiang, Y.5
Kitamura, T.6
Hirose, S.7
Yamamoto, K.8
-
31
-
-
33751567024
-
Gene therapy of arthritis with TCR isolated from the inflamed paw
-
Fujio K, et al. (2006) Gene therapy of arthritis with TCR isolated from the inflamed paw. J Immunol 177:8140-8147. (Pubitemid 44846333)
-
(2006)
Journal of Immunology
, vol.177
, Issue.11
, pp. 8140-8147
-
-
Fujio, K.1
Okamoto, A.2
Araki, Y.3
Shoda, H.4
Tahara, H.5
Tsuno, N.H.6
Takahashi, K.7
Kitamura, T.8
Yamamoto, K.9
-
32
-
-
20444396226
-
Thymic commitment of regulatory T cells is a pathway of TCR-dependent selection that isolates repertoires undergoing positive or negative selection
-
Coutinho A, Caramalho I, Seixas E, Demengeot J (2005) Thymic commitment of regulatory T cells is a pathway of TCR-dependent selection that isolates repertoires undergoing positive or negative selection. Curr Top Microbiol Immunol 293:43-71. (Pubitemid 40796129)
-
(2005)
Current Topics in Microbiology and Immunology
, vol.293
, pp. 43-71
-
-
Coutinho, A.1
Caramalho, I.2
Seixas, E.3
Demengeot, J.4
-
33
-
-
2542456800
-
Commensal bacteria (normal microflora), mucosal immunity and chronic inflammatory and autoimmune diseases
-
DOI 10.1016/j.imlet.2004.02.005, PII S0165247804000379
-
Tlaskalova-Hogenova H, et al. (2004) Commensal bacteria (normal microflora), mucosal immunity and chronic inflammatory and autoimmune diseases. Immunol Lett 93:97-108. (Pubitemid 38678650)
-
(2004)
Immunology Letters
, vol.93
, Issue.2-3
, pp. 97-108
-
-
Tlaskalova-Hogenova, H.1
Stepankova, R.2
Hudcovic, T.3
Tuckova, L.4
Cukrowska, B.5
Lodinova-Zadnikova, R.6
Kozakova, H.7
Rossmann, P.8
Bartova, J.9
Sokol, D.10
Funda, D.P.11
Borovska, D.12
Rehakova, Z.13
Sinkora, J.14
Hofman, J.15
Drastich, P.16
Kokesova, A.17
-
34
-
-
54549122338
-
Innate immunity and intestinal microbiota in the development of type 1 diabetes
-
Wen L, et al. (2008) Innate immunity and intestinal microbiota in the development of type 1 diabetes. Nature 455:1109-1113.
-
(2008)
Nature
, vol.455
, pp. 1109-1113
-
-
Wen, L.1
-
35
-
-
0031114247
-
high T cells to SCID recipients
-
high T cells to SCID recipients. J Immunol 158:3464-3473.
-
(1997)
J Immunol
, vol.158
, pp. 3464-3473
-
-
Aranda, R.1
-
36
-
-
0033523607
-
An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation
-
DOI 10.1084/jem.190.7.995
-
Asseman C, Mauze S, Leach MW, Coffman RL, Powrie F (1999) An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation. J Exp Med 190:995-1004. (Pubitemid 29480828)
-
(1999)
Journal of Experimental Medicine
, vol.190
, Issue.7
, pp. 995-1003
-
-
Asseman, C.1
Mauze, S.2
Leach, M.W.3
Coffman, R.L.4
Powrie, F.5
-
37
-
-
0035284804
-
+ T cells regulate the expansion of peripheral CD4 T cells through the production of IL-10
-
+ T cells regulate the expansion of peripheral CD4 T cells through the production of IL-10. J Immunol 166:3008-3018.
-
(2001)
J Immunol
, vol.166
, pp. 3008-3018
-
-
Annacker, O.1
-
38
-
-
33645979374
-
Transcriptional repressor Blimp-1 is essential for T cell homeostasis and self-tolerance
-
Kallies A, et al. (2006) Transcriptional repressor Blimp-1 is essential for T cell homeostasis and self-tolerance. Nat Immunol 7:466-474.
-
(2006)
Nat Immunol
, vol.7
, pp. 466-474
-
-
Kallies, A.1
-
39
-
-
33646010346
-
Transcriptional repressor Blimp-1 regulates T cell homeostasis and function
-
Martins GA, et al. (2006) Transcriptional repressor Blimp-1 regulates T cell homeostasis and function. Nat Immunol 7:457-465.
-
(2006)
Nat Immunol
, vol.7
, pp. 457-465
-
-
Martins, G.A.1
-
40
-
-
34548131112
-
- precursor cells in the absence of interleukin 10
-
- precursor cells in the absence of interleukin 10. Nat Immunol 8:931-941.
-
(2007)
Nat Immunol
, vol.8
, pp. 931-941
-
-
Maynard, C.L.1
-
41
-
-
51349095960
-
Tuning microenvironments: Induction of regulatory T cells by dendritic cells
-
Belkaid Y, Oldenhove G (2008) Tuning microenvironments: Induction of regulatory T cells by dendritic cells. Immunity 29:362-371.
-
(2008)
Immunity
, vol.29
, pp. 362-371
-
-
Belkaid, Y.1
Oldenhove, G.2
-
42
-
-
34547788180
-
+ DCs induces Foxp3+ regulatory T cells via a TGF-β- And retinoic acid-dependent mechanism
-
+ DCs induces Foxp3+ regulatory T cells via a TGF-β- and retinoic acid-dependent mechanism. J Exp Med 204:1757-1764.
-
(2007)
J Exp Med
, vol.204
, pp. 1757-1764
-
-
Coombes, J.L.1
-
43
-
-
51349158548
-
Plasmacytoid dendritic cells mediate oral tolerance
-
Goubier A, et al. (2008) Plasmacytoid dendritic cells mediate oral tolerance. Immunity 29:464-475.
-
(2008)
Immunity
, vol.29
, pp. 464-475
-
-
Goubier, A.1
-
44
-
-
34247554965
-
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis
-
Rioux JD, et al. (2007) Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat Genet 39:596-604.
-
(2007)
Nat Genet
, vol.39
, pp. 596-604
-
-
Rioux, J.D.1
-
45
-
-
84969213492
-
Genome-wide association study of 14,000 cases of sevencommondiseases and 3,000 shared controls
-
Wellcome Trust Case Control Consortium
-
Wellcome Trust Case Control Consortium (2007) Genome-wide association study of 14,000 cases of sevencommondiseases and 3,000 shared controls. Nature 447:661-678.
-
(2007)
Nature
, vol.447
, pp. 661-678
-
-
-
46
-
-
53349145748
-
Early growth response gene 2 (Egr-2) controls the self-tolerance of T cells and prevents the development of lupuslike autoimmune disease
-
Zhu B, et al. (2008) Early growth response gene 2 (Egr-2) controls the self-tolerance of T cells and prevents the development of lupuslike autoimmune disease. J Exp Med 205:2295-2307.
-
(2008)
J Exp Med
, vol.205
, pp. 2295-2307
-
-
Zhu, B.1
-
47
-
-
0029813545
-
+ TH1-like responses
-
+ TH1-like responses. J Clin Invest 98:1010-1020.
-
(1996)
J Clin Invest
, vol.98
, pp. 1010-1020
-
-
Berg, D.J.1
-
48
-
-
33847370194
-
Regulatory T cells dynamically control the primary immune response to foreign antigen
-
Haribhai D, et al. (2007) Regulatory T cells dynamically control the primary immune response to foreign antigen. J Immunol 178:2961-2972. (Pubitemid 46333175)
-
(2007)
Journal of Immunology
, vol.178
, Issue.5
, pp. 2961-2972
-
-
Haribhai, D.1
Lin, W.2
Relland, L.M.3
Truong, N.4
Williams, C.B.5
Chatila, T.A.6
-
49
-
-
0029812040
-
Constitutive class I-restricted exogenous presentation of self antigens in vivo
-
Kurts C, et al. (1996) Constitutive class I-restricted exogenous presentation of self antigens in vivo. J Exp Med 184:923-930. (Pubitemid 26313550)
-
(1996)
Journal of Experimental Medicine
, vol.184
, Issue.3
, pp. 923-930
-
-
Kurts, C.1
Heath, W.R.2
Carbone, F.R.3
Allison, J.4
Miller, J.F.A.F.5
Kosaka, H.6
Victoria7
-
50
-
-
28744458859
-
Bioconductor: Open software development for computational biology and bioinformatics
-
Gentleman RC, et al. (2004) Bioconductor: Open software development for computational biology and bioinformatics. Genome Biol 5:R80.
-
(2004)
Genome Biol
, vol.5
-
-
Gentleman, R.C.1
-
51
-
-
0034234527
-
Functional reconstitution of class II MHC-restricted T cell immunity mediated by retroviral transfer of the αβ TCR complex
-
Fujio K, et al. (2000) Functional reconstitution of class II MHC-restricted T cell immunity mediated by retroviral transfer of the αβ TCR complex. J Immunol 165:528-532. (Pubitemid 30429547)
-
(2000)
Journal of Immunology
, vol.165
, Issue.1
, pp. 528-532
-
-
Fujio, K.1
Misaki, Y.2
Setoguchi, K.3
Morita, S.4
Kawahata, K.5
Kato, I.6
Nosaka, T.7
Yamamoto, K.8
Kitamura, T.9
|