LAG-3, TGF-β, and cell-intrinsic PD-1 inhibitory pathways contribute to CD8 but not CD4 T-cell tolerance induced by allogeneic BMT with anti-CD40L

Blood

Volumn 117, Issue 20, 2011, Pages 5532-5540

  Lucas, Carrie L ^a   Workman, Creg J ^b   Beyaz, Semir ^a   LoCascio, Samuel ^a   Zhao, Guiling ^a   Vignali, Dario A A ^b   Sykes, Megan ^a,c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^c College of Physicians and Surgeons ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; ANTIGEN; CD40 LIGAND ANTIBODY; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; PROGRAMMED DEATH 1 RECEPTOR; PROTEIN LAG 3; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ADOPTIVE TRANSFER; ALLOGENIC BONE MARROW TRANSPLANTATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN EXPRESSION; ARTICLE; B LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; FEMALE; IMMUNOLOGICAL TOLERANCE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 79956332711     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2010-11-318675     Document Type: Article

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