-
1
-
-
77749304012
-
T-bet, a Th1 transcription factor regulates the expression of Tim-3
-
Anderson AC, Lord GM, Dardalhon V., Lee D.H., Sabatos-Peyton C.A., Glimcher L.H., Kuchroo V.K. 2010. T-bet, a Th1 transcription factor regulates the expression of Tim-3. Eur J Immunol. 40: 859-866.
-
(2010)
Eur J Immunol.
, vol.40
, pp. 859-866
-
-
Anderson, A.C.1
Lord, G.M.2
Dardalhon, V.3
Lee, D.H.4
Sabatos-Peyton, C.A.5
Glimcher, L.H.6
Kuchroo, V.K.7
-
2
-
-
33947190606
-
T Cell Immunoglobulin Mucin-3 Crystal Structure Reveals a Galectin-9-Independent Ligand-Binding Surface
-
DOI 10.1016/j.immuni.2007.01.016, PII S1074761307001781
-
Cao E, Zang X, Ramagopal U.A., Mukhopadhaya A., Fedorov A., Fedorov E., Zencheck W.D., Lary J.W., Cole J.L., Deng H., et al. 2007. T cell immunoglobulin mucin-3 crystal structure reveals a galectin-9-independent ligandbinding surface. Immunity. 26:311-321. (Pubitemid 46413908)
-
(2007)
Immunity
, vol.26
, Issue.3
, pp. 311-321
-
-
Cao, E.1
Zang, X.2
Ramagopal, U.A.3
Mukhopadhaya, A.4
Fedorov, A.5
Fedorov, E.6
Zencheck, W.D.7
Lary, J.W.8
Cole, J.L.9
Deng, H.10
Xiao, H.11
DiLorenzo, T.P.12
Allison, J.P.13
Nathenson, S.G.14
Almo, S.C.15
-
3
-
-
0036233238
-
Regulation of galectin-9 expression and release in Jurkat T cell line cells
-
Chabot S, Kashio Y, Seki M., Shirato Y., Nakamura K., Nishi N., Nakamura T., Matsumoto R., Hirashima M. 2002. Regulation of galectin-9 expression and release in Jurkat T cell line cells. Glycobiology. 12:111-118. (Pubitemid 34428934)
-
(2002)
Glycobiology
, vol.12
, Issue.2
, pp. 111-118
-
-
Chabot, S.1
Kashio, Y.2
Seki, M.3
Shirato, Y.4
Nakamura, K.5
Nishi, N.6
Nakamura, T.7
Matsumoto, R.8
Hirashima, M.9
-
4
-
-
77956409684
-
Tim-3/ galectin-9 pathway: Regulation of Th1 immunity through promotion of CD11b+Ly-6G+ myeloid cells
-
Dardalhon V, Anderson AC, Karman J., Apetoh L., Chandwaskar R., Lee D.H., Cornejo M., Nishi N., Yamauchi A., Quintana F.J., et al. 2010. Tim-3/ galectin-9 pathway: Regulation of Th1 immunity through promotion of CD11b+Ly-6G+ myeloid cells. J Immunol. 185:1383-1392.
-
(2010)
J Immunol.
, vol.185
, pp. 1383-1392
-
-
Dardalhon, V.1
Anderson, A.C.2
Karman, J.3
Apetoh, L.4
Chandwaskar, R.5
Lee, D.H.6
Cornejo, M.7
Nishi, N.8
Yamauchi, A.9
Quintana, F.J.10
-
5
-
-
77449124815
-
N- and O-glycans modulate galectin-1 binding, CD45 signaling, and T cell death
-
Earl LA, Bi S, Baum LG. 2010. N- and O-glycans modulate galectin-1 binding, CD45 signaling, and T cell death. J Biol Chem. 285:2232-2244.
-
(2010)
J Biol Chem.
, vol.285
, pp. 2232-2244
-
-
Earl, L.A.1
Bi, S.2
Baum, L.G.3
-
6
-
-
69449091993
-
Negative immune regulator Tim-3 is overexpressed on T cells in hepatitis C virus infection and its blockade rescues dysfunctional CD4+ and CD8+ T cells
-
Golden-Mason L, Palmer BE, Kassam N., Townshend-Bulson L., Livingston S., McMahon B.J., Castelblanco N., Kuchroo V., Gretch D.R., Rosen H.R. 2009. Negative immune regulator Tim-3 is overexpressed on T cells in hepatitis C virus infection and its blockade rescues dysfunctional CD4+ and CD8+ T cells. J Virol. 83:9122-9130.
-
(2009)
J Virol.
, vol.83
, pp. 9122-9130
-
-
Golden-Mason, L.1
Palmer, B.E.2
Kassam, N.3
Townshend-Bulson, L.4
Livingston, S.5
McMahon, B.J.6
Castelblanco, N.7
Kuchroo, V.8
Gretch, D.R.9
Rosen, H.R.10
-
7
-
-
70349248367
-
TIM-3 is expressed on activated human CD4+ T cells and regulates Th1 and Th17 cytokines
-
Hastings WD, Anderson DE, Kassam N., Koguchi K., Greenfield E.A., Kent S.C., Zheng X.X., Strom T.B., Hafler D.A., Kuchroo V.K. 2009. TIM-3 is expressed on activated human CD4+ T cells and regulates Th1 and Th17 cytokines. Eur J Immunol. 39:2492-2501.
-
(2009)
Eur J Immunol.
, vol.39
, pp. 2492-2501
-
-
Hastings, W.D.1
Anderson, D.E.2
Kassam, N.3
Koguchi, K.4
Greenfield, E.A.5
Kent, S.C.6
Zheng, X.X.7
Strom, T.B.8
Hafler, D.A.9
Kuchroo, V.K.10
-
8
-
-
1542367461
-
Galectin-9 in physiological and pathological conditions
-
DOI 10.1023/B:GLYC.0000014090.63206.2f
-
Hirashima M, Kashio Y, Nishi N., Yamauchi A., Imaizumi T.A., Kageshita T., Saita N., Nakamura T. 2004. Galectin-9 in physiological and pathological conditions. Glycoconj J. 19:593-600. (Pubitemid 38460942)
-
(2002)
Glycoconjugate Journal
, vol.19
, Issue.7-9
, pp. 593-600
-
-
Hirashima, M.1
Kashio, Y.2
Nishi, N.3
Yamauchi, A.4
Imaizumi, T.-A.5
Kageshita, T.6
Saita, N.7
Nakamura, T.8
-
9
-
-
58149277359
-
Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection
-
Jones RB, Ndhlovu LC, Barbour J.D., Sheth P.M., Jha A.R., Long B.R., Wong J.C., Satkunarajah M., Schweneker M., Chapman J.M., et al. 2008. Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection. J Exp Med. 205:2763-2779.
-
(2008)
J Exp Med.
, vol.205
, pp. 2763-2779
-
-
Jones, R.B.1
Ndhlovu, L.C.2
Barbour, J.D.3
Sheth, P.M.4
Jha, A.R.5
Long, B.R.6
Wong, J.C.7
Satkunarajah, M.8
Schweneker, M.9
Chapman, J.M.10
-
10
-
-
2142646543
-
A proline-rich motif in the C terminus of Akt contributes to its localization in the immunological synapse
-
Kane LP, Mollenauer MN, Weiss A 2004. A proline-rich motif in the C terminus of Akt contributes to its localization in the immunological synapse. J Immunol. 172:5441-5449. (Pubitemid 38542044)
-
(2004)
Journal of Immunology
, vol.172
, Issue.9
, pp. 5441-5449
-
-
Kane, L.P.1
Mollenauer, M.N.2
Weiss, A.3
-
11
-
-
34447267678
-
Galectin-9 inhibits CD44-hyaluronan interaction and suppresses a murine model of allergic asthma
-
DOI 10.1164/rccm.200608-1243OC
-
Katoh S, Ishii N, Nobumoto A., Takeshita K., Dai S.Y., Shinonaga R., Niki T., Nishi N., Tominaga A., Yamauchi A. 2007. Galectin-9 inhibits CD44- hyaluronan interaction and suppresses a murine model of allergic asthma. Am J Respir Crit Care Med. 176:27-35. (Pubitemid 47048051)
-
(2007)
American Journal of Respiratory and Critical Care Medicine
, vol.176
, Issue.1
, pp. 27-35
-
-
Katoh, S.1
Ishii, N.2
Nobumoto, A.3
Takeshita, K.4
Dai, S.-Y.5
Shinonaga, R.6
Niki, T.7
Nishi, N.8
Tominaga, A.9
Yamauchi, A.10
Hirashima, M.11
-
12
-
-
0022854422
-
Specificity of binding of three soluble rat lung lectins to substituted and unsubstituted mammalian β-galactosides
-
Leffler H, Barondes SH. 1986. Specificity of binding of three soluble rat lung lectins to substituted and unsubstituted mammalian beta-galactosides. J Biol Chem. 261:10119-10126. (Pubitemid 17221945)
-
(1986)
Journal of Biological Chemistry
, vol.261
, Issue.22
, pp. 10119-10126
-
-
Leffler, H.1
Barondes, S.H.2
-
13
-
-
75749101401
-
Galectins: Regulators of acute and chronic inflammation
-
Liu FT, Rabinovich GA. 2010. Galectins: Regulators of acute and chronic inflammation. Ann N Y Acad Sci. 1183:158-182.
-
(2010)
Ann N y Acad Sci.
, vol.1183
, pp. 158-182
-
-
Liu, F.T.1
Rabinovich, G.A.2
-
14
-
-
71849095178
-
Galectin-9 increases Tim-3+ dendritic cells and CD8+ T cells and enhances antitumor immunity via galectin-9-Tim-3 interactions
-
Nagahara K, Arikawa T, Oomizu S., Kontani K., Nobumoto A., Tateno H., Watanabe K., Niki T., Katoh S., Miyake M., et al. 2008. Galectin-9 increases Tim-3+ dendritic cells and CD8+ T cells and enhances antitumor immunity via galectin-9-Tim-3 interactions. J Immunol. 181:7660-7669.
-
(2008)
J Immunol.
, vol.181
, pp. 7660-7669
-
-
Nagahara, K.1
Arikawa, T.2
Oomizu, S.3
Kontani, K.4
Nobumoto, A.5
Tateno, H.6
Watanabe, K.7
Niki, T.8
Katoh, S.9
Miyake, M.10
-
15
-
-
16344392326
-
Development of highly stable galectins: Truncation of the linker peptide confers protease-resistance on tandem-repeat type galectins
-
DOI 10.1016/j.febslet.2005.02.054
-
Nishi N, Itoh A, Fujiyama A., Yoshida N., Araya S., Hirashima M., Shoji H., Nakamura T. 2005. Development of highly stable galectins: Truncation of the linker peptide confers protease-resistance on tandem-repeat type galectins. FEBS Lett. 579:2058-2064. (Pubitemid 40469670)
-
(2005)
FEBS Letters
, vol.579
, Issue.10
, pp. 2058-2064
-
-
Nishi, N.1
Itoh, A.2
Fujiyama, A.3
Yoshida, N.4
Araya, S.-I.5
Hirashima, M.6
Shoji, H.7
Nakamura, T.8
-
16
-
-
0034267915
-
Cutting edge: CD7 delivers a pro-apoptotic signal during galectin-1-induced T cell death
-
Pace KE, Hahn HP, Pang M., Nguyen J.T., Baum L.G. 2000. Cutting edge: CD7 delivers a pro-apoptotic signal during galectin-1-induced T cell death. J Immunol. 165:2331-2334. (Pubitemid 30660673)
-
(2000)
Journal of Immunology
, vol.165
, Issue.5
, pp. 2331-2334
-
-
Pace, K.E.1
Hahn, H.P.2
Pang, M.3
Nguyen, J.T.4
Baum, L.G.5
-
17
-
-
0033215424
-
Restricted receptor segregation into membrane microdomains occurs on human T cells during apoptosis induced by galectin-1
-
Pace KE, Lee C, Stewart P.L., Baum L.G. 1999. Restricted receptor segregation into membrane microdomains occurs on human T cells during apoptosis induced by galectin-1. J Immunol. 163:3801-3811. (Pubitemid 29450905)
-
(1999)
Journal of Immunology
, vol.163
, Issue.7
, pp. 3801-3811
-
-
Pace, K.E.1
Lee, C.2
Stewart, P.L.3
Baum, L.G.4
-
18
-
-
0242539820
-
Interaction of Tim-3 and Tim-3 ligand regulates T helper type 1 responses and induction of peripheral tolerance
-
DOI 10.1038/ni988
-
Sabatos CA, Chakravarti S, Cha E., Schubart A., Sanchez-Fueyo A., Zheng X. X., Coyle A.J., Strom T.B., Freeman G.J., Kuchroo V.K. 2003. Interaction of Tim-3 and Tim-3 ligand regulates T helper type 1 responses and induction of peripheral tolerance. Nat Immunol. 4:1102-1110. (Pubitemid 37428038)
-
(2003)
Nature Immunology
, vol.4
, Issue.11
, pp. 1102-1110
-
-
Sabatos, C.A.1
Chakravarti, S.2
Cha, E.3
Schubart, A.4
Sanchez-Fueyo, A.5
Zheng, X.X.6
Coyle, A.J.7
Strom, T.B.8
Freeman, G.J.9
Kuchroo, V.K.10
-
19
-
-
0242708767
-
Tim-3 inhibits T helper type 1-mediated auto- and alloimmune responses and promotes immunological tolerance
-
DOI 10.1038/ni987
-
Sanchez-Fueyo A, Tian J, Picarella D., Domenig C., Zheng X.X., Sabatos C. A., Manlongat N., Bender O., Kamradt T., Kuchroo V.K., et al. 2003. Tim-3 inhibits T helper type 1-mediated auto- and alloimmune responses and promotes immunological tolerance. Nat Immunol. 4:1093-1101. (Pubitemid 37428037)
-
(2003)
Nature Immunology
, vol.4
, Issue.11
, pp. 1093-1101
-
-
Sanchez-Fueyo, A.1
Tian, J.2
Picarella, D.3
Domenig, C.4
Zheng, X.X.5
Sabatos, C.A.6
Manlongat, N.7
Bender, O.8
Kamradt, T.9
Kuchroo, V.K.10
Gutierrez-Ramos, J.-C.11
Coyle, A.J.12
Strom, T.B.13
-
20
-
-
64849111809
-
Role of Tim-3/ galectin-9 inhibitory interaction in viral-induced immunopathology: Shifting the balance toward regulators
-
Sehrawat S, Suryawanshi A, Hirashima M., Rouse B.T. 2009. Role of Tim-3/ galectin-9 inhibitory interaction in viral-induced immunopathology: Shifting the balance toward regulators. J Immunol. 182:3191-3201.
-
(2009)
J Immunol.
, vol.182
, pp. 3191-3201
-
-
Sehrawat, S.1
Suryawanshi, A.2
Hirashima, M.3
Rouse, B.T.4
-
21
-
-
40849120400
-
Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis
-
Seki M, Oomizu S, Sakata K.M., Sakata A., Arikawa T., Watanabe K., Ito K., Takeshita K., Niki T., Saita N., et al. 2008. Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis. Clin Immunol. 127:78-88.
-
(2008)
Clin Immunol.
, vol.127
, pp. 78-88
-
-
Seki, M.1
Oomizu, S.2
Sakata, K.M.3
Sakata, A.4
Arikawa, T.5
Watanabe, K.6
Ito, K.7
Takeshita, K.8
Niki, T.9
Saita, N.10
-
22
-
-
30744445427
-
Galectin-3 and galectin-1 bind distinct cell surface glycoprotein receptors to induce T cell death
-
Stillman BN, Hsu DK, Pang M., Brewer C.F., Johnson P., Liu F.T., Baum L.G. 2006. Galectin-3 and galectin-1 bind distinct cell surface glycoprotein receptors to induce T cell death. J Immunol. 176:778-789. (Pubitemid 43099674)
-
(2006)
Journal of Immunology
, vol.176
, Issue.2
, pp. 778-789
-
-
Stillman, B.N.1
Hsu, D.K.2
Pang, M.3
Brewer, C.F.4
Johnson, P.5
Liu, F.-T.6
Baum, L.G.7
-
23
-
-
65249141172
-
Galectin-1 induces reversible phosphatidylserine exposure at the plasma membrane
-
Stowell SR, Karmakar S, Arthur C.M., Ju T., Rodrigues L.C., Riul T.B., Dias- Baruffi M., Miner J., McEver R.P., Cummings R.D. 2009. Galectin-1 induces reversible phosphatidylserine exposure at the plasma membrane. Mol Biol Cell. 20:1408-1418.
-
(2009)
Mol Biol Cell.
, vol.20
, pp. 1408-1418
-
-
Stowell, S.R.1
Karmakar, S.2
Arthur, C.M.3
Ju, T.4
Rodrigues, L.C.5
Riul, T.B.6
Dias- Baruffi, M.7
Miner, J.8
McEver, R.P.9
Cummings, R.D.10
-
24
-
-
0034677646
-
A novel transcription factor, T-bet, directs Th1 lineage commitment
-
Szabo SJ, Kim ST, Costa G.L., Zhang X., Fathman C.G., Glimcher L.H. 2000. A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell. 100:655-669.
-
(2000)
Cell.
, vol.100
, pp. 655-669
-
-
Szabo, S.J.1
Kim, S.T.2
Costa, G.L.3
Zhang, X.4
Fathman, C.G.5
Glimcher, L.H.6
-
25
-
-
34547099820
-
H-17 effector cells selectively regulates susceptibility to cell death
-
DOI 10.1038/ni1482, PII NI1482
-
Toscano MA, Bianco GA, Ilarregui J.M., Croci D.O., Correale J., Hernandez J.D., Zwirner N.W., Poirier F., Riley E.M., Baum L.G., et al. 2007. Differential glycosylation of TH1, TH2 and TH-17 effector cells selectively regulates susceptibility to cell death. Nat Immunol. 8:825-834. (Pubitemid 47099035)
-
(2007)
Nature Immunology
, vol.8
, Issue.8
, pp. 825-834
-
-
Toscano, M.A.1
Bianco, G.A.2
Ilarregui, J.M.3
Croci, D.O.4
Correale, J.5
Hernandez, J.D.6
Zwirner, N.W.7
Poirier, F.8
Riley, E.M.9
Baum, L.G.10
Rabinovich, G.A.11
-
26
-
-
0030989330
-
Developmental regulation, expression, and apoptotic potential of galectin-9, a β-galactoside binding lectin
-
Wada J, Ota K, Kumar A., Wallner E.I., Kanwar Y.S. 1997. Developmental regulation, expression, and apoptotic potential of galectin-9, a betagalactoside binding lectin. J Clin Invest. 99:2452-2461. (Pubitemid 27227724)
-
(1997)
Journal of Clinical Investigation
, vol.99
, Issue.10
, pp. 2452-2461
-
-
Wada, J.1
Ota, K.2
Kumar, A.3
Wallner, E.I.4
Kanwar, Y.S.5
-
28
-
-
30044434075
-
The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity
-
DOI 10.1038/ni1271, PII N1271
-
Zhu C, Anderson AC, Schubart A., Xiong H., Imitola J., Khoury S.J., Zheng X.X., Strom T.B., Kuchroo V.K. 2005. The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity. Nat Immunol. 6:1245-1252. (Pubitemid 43045636)
-
(2005)
Nature Immunology
, vol.6
, Issue.12
, pp. 1245-1252
-
-
Zhu, C.1
Anderson, A.C.2
Schubart, A.3
Xiong, H.4
Imitola, J.5
Khoury, S.J.6
Zheng, X.X.7
Strom, T.B.8
Kuchroo, V.K.9
|