T-cell immunoglobulin and ITIM domain (TIGIT) receptor/poliovirus receptor (PVR) ligand engagement suppresses interferon-γ production of natural killer cells via β-arrestin 2-mediated negative signaling

Journal of Biological Chemistry

Volumn 289, Issue 25, 2014, Pages 17647-17657

  Li, Man ^a,b   Xia, Pengyan ^a,b   Du, Ying ^a   Liu, Shengwu ^a,b   Huang, Guanling ^a,b   Chen, Jun ^a,b   Zhang, Honglian ^a   Hou, Ning ^c   Cheng, Xuan ^c   Zhou, Luyu ^d   Li, Peifeng ^d   Yang, Xiao ^c   Fan, Zusen ^a  

^a INSTITUTE OF BIOPHYSICS   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c BEIJING INSTITUTE OF BIOTECHNOLOGY   (China)

^d INSTITUTE OF ZOOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTICS; CELL MEMBRANES; CHEMICAL ACTIVATION; CYTOLOGY; GLYCOPROTEINS; LIGANDS; PHOSPHATASES; SHIPS; SIGNALING; T-CELLS;

ARRESTINS; AUTOUBIQUITINATION; CYTOKINE SECRETIONS; INOSITOL PHOSPHATASE; KNOCK OUTS; NATURAL KILLER CELLS; NK CELLS; TRANSGENICS;

CELL SIGNALING;

BETA ARRESTIN; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MEMBRANE PROTEIN; POLIOVIRUS RECEPTOR LIGAND; SH2 CONTAINING INOSITOL PHOSPHATASE 1; T CELL IMMUNOGLOBULIN AND ITIM DOMAIN RECEPTOR; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME REPRESSION; FEMALE; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; LASER MICROSCOPY; MOUSE; NATURAL KILLER CELL; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; UBIQUITINATION;

IMMUNOLOGY; INNATE IMMUNITY; INTERFERON; NATURAL KILLER CELLS (NK CELLS); SIGNALING;

ANIMALS; ARRESTINS; CD8-POSITIVE T-LYMPHOCYTES; CELL LINE; HUMANS; IMMUNOLOGIC CAPPING; INTERFERON-GAMMA; KILLER CELLS, NATURAL; MICE; MICE, KNOCKOUT; PHOSPHORIC MONOESTER HYDROLASES; RECEPTORS, IMMUNOLOGIC; RECEPTORS, VIRUS; SIGNAL TRANSDUCTION; TNF RECEPTOR-ASSOCIATED FACTOR 6;

EID: 84903470168     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.572420     Document Type: Article

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