PD-1 and LAG-3 inhibitory co-receptors act synergistically to prevent autoimmunity in mice

Journal of Experimental Medicine

Volumn 208, Issue 2, 2011, Pages 395-407

  Okazaki, Taku ^a,b,c   Okazaki, Il Mi ^a   Wang, Jian ^c,g   Sugiura, Daisuke ^a   Nakaki, Fumio ^c   Yoshida, Taku ^c,h   Kato, Yu ^c,h   Fagarasan, Sidonia ^d   Muramatsu, Masamichi ^e   Eto, Tomoo ^f   Hioki, Kyoji ^f   Honjo, Tasuku ^c  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c KYOTO UNIVERSITY   (Japan)

^d RIKEN   (Japan)

^e KANAZAWA UNIVERSITY   (Japan)

^f CENTRAL INSTITUTE FOR EXPERIMENTAL ANIMALS   (Japan)

^g FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^h EISAI CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION INDUCED CYTIDINE DEAMINASE; PROGRAMMED DEATH 1 RECEPTOR;

ARTICLE; AUTOIMMUNE DISEASE; AUTOIMMUNITY; BAGG ALBINO MOUSE; CONTROLLED STUDY; FEMALE; GENE MUTATION; INSULIN DEPENDENT DIABETES MELLITUS; LYMPHOCYTE ACTIVATION; MALE; MOUSE; MOUSE STRAIN; MYOCARDITIS; NONHUMAN; NONOBESE DIABETIC MOUSE; PRIORITY JOURNAL; PROTEIN DEFICIENCY; REGULATOR GENE; REGULATORY MECHANISM;

ANIMALS; ANTIGENS, CD; ANTIGENS, SURFACE; APOPTOSIS REGULATORY PROTEINS; AUTOIMMUNITY; DIABETES MELLITUS, TYPE 1; DISEASE MODELS, ANIMAL; DNA PRIMERS; FLOW CYTOMETRY; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; MICROSATELLITE REPEATS; MYOCARDITIS; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; POLYMORPHISM, SINGLE NUCLEOTIDE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; T-LYMPHOCYTES, REGULATORY;

EID: 79951684125     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20100466     Document Type: Article

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