Tim-3 inhibits T helper type 1-mediated auto- and alloimmune responses and promotes immunological tolerance

Nature Immunology

Volumn 4, Issue 11, 2003, Pages 1093-1101

  Sánchez Fueyo, Alberto ^a   Tian, Jane ^b   Picarella, Dominic ^b   Domenig, Christoph ^a   Zheng, Xin Xiao ^a   Sabatos, Catherine A ^a   Manlongat, Natasha ^c   Bender, Orissa ^d   Kamradt, Thomas ^d   Kuchroo, Vijay K ^a   Gutiérrez Ramos, José Carlos ^b   Coyle, Anthony J ^b   Strom, Terry B ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MILLENNIUM PHARMACEUTICALS INC   (United States)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

^d DEUTSCHES RHEUMA FORSCHUNGSZENTRUM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD40 LIGAND; IMMUNOGLOBULIN; INTERLEUKIN 2 RECEPTOR; MEMBRANE PROTEIN; MUCIN; PROTEIN TIM 3; UNCLASSIFIED DRUG;

ALLOIMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIGEN SPECIFICITY; ARTICLE; AUTOIMMUNITY; CELL SPECIFICITY; CELLULAR IMMUNITY; CONTROLLED STUDY; DIABETES MELLITUS; DOWN REGULATION; HELPER CELL; IMMUNE RESPONSE; IMMUNOLOGICAL TOLERANCE; IMMUNOSUPPRESSIVE TREATMENT; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE SUBPOPULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; TH1 CELL; TRANSPLANTATION TOLERANCE;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; IMMUNE SYSTEM; IMMUNE TOLERANCE; MICE; MICE, INBRED NOD; RECEPTORS, INTERLEUKIN-2; RECEPTORS, VIRUS; SIGNAL TRANSDUCTION; TH1 CELLS;

EID: 0242708767     PISSN: 15292908     EISSN: None     Source Type: Journal    
DOI: 10.1038/ni987     Document Type: Article

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