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Volumn 7, Issue 2, 2012, Pages

TIM-3 expression characterizes regulatory T cells in tumor tissues and is associated with lung cancer progression

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; MEMBRANE PROTEIN; PROGRAMMED DEATH 1 RECEPTOR; T CELL IMMUNOGLOBULIN 3; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG; HAVCR2 PROTEIN, HUMAN;

EID: 84857159981     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0030676     Document Type: Article
Times cited : (325)

References (21)
  • 1
    • 33749319703 scopus 로고    scopus 로고
    • Type, density, and location of immune cells within human colorectal tumors predict clinical outcome
    • Galon J, Costes A, Sanchez-Cabo F, Kirilovsky A, Mlecnik B, et al. (2006) Type, density, and location of immune cells within human colorectal tumors predict clinical outcome. Science 313: 1960-1964.
    • (2006) Science , vol.313 , pp. 1960-1964
    • Galon, J.1    Costes, A.2    Sanchez-Cabo, F.3    Kirilovsky, A.4    Mlecnik, B.5
  • 2
    • 16844379997 scopus 로고    scopus 로고
    • Immunosuppressive networks in the tumour environment and their therapeutic relevance
    • Zou W, (2005) Immunosuppressive networks in the tumour environment and their therapeutic relevance. Nat Rev Cancer 5: 263-274.
    • (2005) Nat Rev Cancer , vol.5 , pp. 263-274
    • Zou, W.1
  • 3
    • 33645286546 scopus 로고    scopus 로고
    • Regulatory T cells, tumour immunity and immunotherapy
    • Zou W, (2006) Regulatory T cells, tumour immunity and immunotherapy. Nat Rev Immunol 6: 295-307.
    • (2006) Nat Rev Immunol , vol.6 , pp. 295-307
    • Zou, W.1
  • 4
    • 77957723967 scopus 로고    scopus 로고
    • Upregulation of Tim-3 and PD-1 expression is associated with tumor antigen-specific CD8+ T cell dysfunction in melanoma patients
    • Fourcade J, Sun Z, Benallaoua M, Guillaume P, Luescher IF, et al. (2010) Upregulation of Tim-3 and PD-1 expression is associated with tumor antigen-specific CD8+ T cell dysfunction in melanoma patients. J Exp Med 207: 2175-2186.
    • (2010) J Exp Med , vol.207 , pp. 2175-2186
    • Fourcade, J.1    Sun, Z.2    Benallaoua, M.3    Guillaume, P.4    Luescher, I.F.5
  • 5
    • 77957744369 scopus 로고    scopus 로고
    • Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity
    • Sakuishi K, Apetoh L, Sullivan JM, Blazar BR, Kuchroo VK, et al. (2010) Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity. J Exp Med 207: 2187-2194.
    • (2010) J Exp Med , vol.207 , pp. 2187-2194
    • Sakuishi, K.1    Apetoh, L.2    Sullivan, J.M.3    Blazar, B.R.4    Kuchroo, V.K.5
  • 6
    • 41549169557 scopus 로고    scopus 로고
    • Contextual regulation of inflammation: a duet by transforming growth factor-beta and interleukin-10
    • Li MO, Flavell RA, (2008) Contextual regulation of inflammation: a duet by transforming growth factor-beta and interleukin-10. Immunity 28: 468-476.
    • (2008) Immunity , vol.28 , pp. 468-476
    • Li, M.O.1    Flavell, R.A.2
  • 7
    • 44349150012 scopus 로고    scopus 로고
    • Inhibitory B7-family molecules in the tumour microenvironment
    • Zou W, Chen L, (2008) Inhibitory B7-family molecules in the tumour microenvironment. Nat Rev Immunol 8: 467-477.
    • (2008) Nat Rev Immunol , vol.8 , pp. 467-477
    • Zou, W.1    Chen, L.2
  • 8
    • 79961167936 scopus 로고    scopus 로고
    • T-cell-mediated tumor immune surveillance and expression of B7 co-inhibitory molecules in cancers of the upper gastrointestinal tract
    • Lu B, Chen L, Liu L, Zhu Y, Wu C, et al. (2011) T-cell-mediated tumor immune surveillance and expression of B7 co-inhibitory molecules in cancers of the upper gastrointestinal tract. Immunol Res 50: 269-275.
    • (2011) Immunol Res , vol.50 , pp. 269-275
    • Lu, B.1    Chen, L.2    Liu, L.3    Zhu, Y.4    Wu, C.5
  • 9
    • 36248967595 scopus 로고    scopus 로고
    • Promotion of tissue inflammation by the immune receptor Tim-3 expressed on innate immune cells
    • Anderson AC, Anderson DE, Bregoli L, Hastings WD, Kassam N, et al. (2007) Promotion of tissue inflammation by the immune receptor Tim-3 expressed on innate immune cells. Science 318: 1141-1143.
    • (2007) Science , vol.318 , pp. 1141-1143
    • Anderson, A.C.1    Anderson, D.E.2    Bregoli, L.3    Hastings, W.D.4    Kassam, N.5
  • 10
    • 70349248367 scopus 로고    scopus 로고
    • TIM-3 is expressed on activated human CD4+ T cells and regulates Th1 and Th17 cytokines
    • Hastings WD, Anderson DE, Kassam N, Koguchi K, Greenfield EA, et al. (2009) TIM-3 is expressed on activated human CD4+ T cells and regulates Th1 and Th17 cytokines. Eur J Immunol 39: 2492-2501.
    • (2009) Eur J Immunol , vol.39 , pp. 2492-2501
    • Hastings, W.D.1    Anderson, D.E.2    Kassam, N.3    Koguchi, K.4    Greenfield, E.A.5
  • 11
    • 0037203867 scopus 로고    scopus 로고
    • Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease
    • Monney L, Sabatos CA, Gaglia JL, Ryu A, Waldner H, et al. (2002) Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease. Nature 415: 536-541.
    • (2002) Nature , vol.415 , pp. 536-541
    • Monney, L.1    Sabatos, C.A.2    Gaglia, J.L.3    Ryu, A.4    Waldner, H.5
  • 12
    • 30044434075 scopus 로고    scopus 로고
    • The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity
    • Zhu C, Anderson AC, Schubart A, Xiong H, Imitola J, et al. (2005) The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity. Nat Immunol 6: 1245-1252.
    • (2005) Nat Immunol , vol.6 , pp. 1245-1252
    • Zhu, C.1    Anderson, A.C.2    Schubart, A.3    Xiong, H.4    Imitola, J.5
  • 13
    • 0242539820 scopus 로고    scopus 로고
    • Interaction of Tim-3 and Tim-3 ligand regulates T helper type 1 responses and induction of peripheral tolerance
    • Sabatos CA, Chakravarti S, Cha E, Schubart A, Sanchez-Fueyo A, et al. (2003) Interaction of Tim-3 and Tim-3 ligand regulates T helper type 1 responses and induction of peripheral tolerance. Nat Immunol 4: 1102-1110.
    • (2003) Nat Immunol , vol.4 , pp. 1102-1110
    • Sabatos, C.A.1    Chakravarti, S.2    Cha, E.3    Schubart, A.4    Sanchez-Fueyo, A.5
  • 14
    • 0242708767 scopus 로고    scopus 로고
    • Tim-3 inhibits T helper type 1-mediated auto- and alloimmune responses and promotes immunological tolerance
    • Sanchez-Fueyo A, Tian J, Picarella D, Domenig C, Zheng XX, et al. (2003) Tim-3 inhibits T helper type 1-mediated auto- and alloimmune responses and promotes immunological tolerance. Nat Immunol 4: 1093-1101.
    • (2003) Nat Immunol , vol.4 , pp. 1093-1101
    • Sanchez-Fueyo, A.1    Tian, J.2    Picarella, D.3    Domenig, C.4    Zheng, X.X.5
  • 15
    • 58149277359 scopus 로고    scopus 로고
    • Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection
    • Jones RB, Ndhlovu LC, Barbour JD, Sheth PM, Jha AR, et al. (2008) Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection. J Exp Med 205: 2763-2779.
    • (2008) J Exp Med , vol.205 , pp. 2763-2779
    • Jones, R.B.1    Ndhlovu, L.C.2    Barbour, J.D.3    Sheth, P.M.4    Jha, A.R.5
  • 16
    • 78649853665 scopus 로고    scopus 로고
    • T-bet and eomesodermin are required for T cell-mediated antitumor immune responses
    • Zhu Y, Ju S, Chen E, Dai S, Li C, et al. (2010) T-bet and eomesodermin are required for T cell-mediated antitumor immune responses. J Immunol 185: 3174-3183.
    • (2010) J Immunol , vol.185 , pp. 3174-3183
    • Zhu, Y.1    Ju, S.2    Chen, E.3    Dai, S.4    Li, C.5
  • 17
    • 34247271308 scopus 로고    scopus 로고
    • Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3
    • Williams LM, Rudensky AY, (2007) Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3. Nat Immunol 8: 277-284.
    • (2007) Nat Immunol , vol.8 , pp. 277-284
    • Williams, L.M.1    Rudensky, A.Y.2
  • 18
    • 78650635632 scopus 로고    scopus 로고
    • TIM-3: a novel regulatory molecule of alloimmune activation
    • Boenisch O, D'Addio F, Watanabe T, Elyaman W, Magee CN, et al. (2010) TIM-3: a novel regulatory molecule of alloimmune activation. J Immunol 185: 5806-5819.
    • (2010) J Immunol , vol.185 , pp. 5806-5819
    • Boenisch, O.1    D'Addio, F.2    Watanabe, T.3    Elyaman, W.4    Magee, C.N.5
  • 19
    • 48249147441 scopus 로고    scopus 로고
    • Programmed death 1 ligand signaling regulates the generation of adaptive Foxp3+CD4+ regulatory T cells
    • Wang L, Pino-Lagos K, de Vries VC, Guleria I, Sayegh MH, et al. (2008) Programmed death 1 ligand signaling regulates the generation of adaptive Foxp3+CD4+ regulatory T cells. Proc Natl Acad Sci U S A 105: 9331-9336.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 9331-9336
    • Wang, L.1    Pino-Lagos, K.2    de Vries, V.C.3    Guleria, I.4    Sayegh, M.H.5
  • 20
    • 40849120400 scopus 로고    scopus 로고
    • Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis
    • Seki M, Oomizu S, Sakata KM, Sakata A, Arikawa T, et al. (2008) Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis. Clin Immunol 127: 78-88.
    • (2008) Clin Immunol , vol.127 , pp. 78-88
    • Seki, M.1    Oomizu, S.2    Sakata, K.M.3    Sakata, A.4    Arikawa, T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.