-
1
-
-
0025074907
-
In vitro selection of RNA molecules that bind specific ligands
-
Ellington, A.D.; Szostak, J.W. In vitro selection of RNA molecules that bind specific ligands. Nature 1990, 346, 818-822.
-
(1990)
Nature
, vol.346
, pp. 818-822
-
-
Ellington, A.D.1
Szostak, J.W.2
-
2
-
-
0025194307
-
Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage t4 DNA polymerase
-
Tuerk, C.; Gold, L. Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage t4 DNA polymerase. Science 1990, 249, 505-510.
-
(1990)
Science
, vol.249
, pp. 505-510
-
-
Tuerk, C.1
Gold, L.2
-
3
-
-
0030221025
-
Aptamer structures from a to ζ
-
Feigon, J.; Dieckmann, T.; Smith, F.W. Aptamer structures from a to ζ. Chem. Biol. 1996, 3, 611-617.
-
(1996)
Chem. Biol.
, vol.3
, pp. 611-617
-
-
Feigon, J.1
Dieckmann, T.2
Smith, F.W.3
-
4
-
-
0031563817
-
Structure, recognition and adaptive binding in RNA aptamer complexes1
-
Patel, D.J.; Suri, A.K.; Jiang, F.; Jiang, L.; Fan, P.; Kumar, R.A.; Nonin, S. Structure, recognition and adaptive binding in RNA aptamer complexes1. J. Mol. Biol. 1997, 272, 645-664.
-
(1997)
J. Mol. Biol.
, vol.272
, pp. 645-664
-
-
Patel, D.J.1
Suri, A.K.2
Jiang, F.3
Jiang, L.4
Fan, P.5
Kumar, R.A.6
Nonin, S.7
-
5
-
-
0034603154
-
Adaptive recognition by nucleic acid aptamers
-
Hermann, T.; Patel, D.J. Adaptive recognition by nucleic acid aptamers. Science 2000, 287, 820-825.
-
(2000)
Science
, vol.287
, pp. 820-825
-
-
Hermann, T.1
Patel, D.J.2
-
6
-
-
0037325327
-
Aptamer structures: A preview into regulatory pathways?
-
Piganeau, N.; Schroeder, R. Aptamer structures: A preview into regulatory pathways? Chem. Biol. 2003, 10, 103-104.
-
(2003)
Chem. Biol.
, vol.10
, pp. 103-104
-
-
Piganeau, N.1
Schroeder, R.2
-
8
-
-
0028224199
-
High-resolution molecular discrimination by RNA
-
Jenison, R.; Gill, S.; Pardi, A.; Polisky, B. High-resolution molecular discrimination by RNA. Science 1994, 263, 1425-1429.
-
(1994)
Science
, vol.263
, pp. 1425-1429
-
-
Jenison, R.1
Gill, S.2
Pardi, A.3
Polisky, B.4
-
9
-
-
0029924638
-
RNA aptamers that bind L-arginine with sub-micromolar dissociation constants and high enantioselectivity
-
Geiger, A.; Burgstaller, P.; von der Eltz, H.; Roeder, A.; Famulok, M. RNA aptamers that bind L-arginine with sub-micromolar dissociation constants and high enantioselectivity. Nucleic Acids Res. 1996, 24, 1029-1036.
-
(1996)
Nucleic Acids Res.
, vol.24
, pp. 1029-1036
-
-
Geiger, A.1
Burgstaller, P.2
von der Eltz, H.3
Roeder, A.4
Famulok, M.5
-
10
-
-
0018788367
-
Thermal stability and protein structure
-
Argos, P.; Rossmann, M.G.; Grau, U.M.; Zuber, H.; Frank, G.; Tratschin, J.D. Thermal stability and protein structure. Biochemistry 1979, 18, 5698-5703.
-
(1979)
Biochemistry
, vol.18
, pp. 5698-5703
-
-
Argos, P.1
Rossmann, M.G.2
Grau, U.M.3
Zuber, H.4
Frank, G.5
Tratschin, J.D.6
-
11
-
-
0025741733
-
Rapid renaturation of complementary DNA strands mediated by cationic detergents: A role for high-probability binding domains in enhancing the kinetics of molecular assembly processes
-
Pontius, B.W.; Berg, P. Rapid renaturation of complementary DNA strands mediated by cationic detergents: A role for high-probability binding domains in enhancing the kinetics of molecular assembly processes. Proc. Natl. Acad. Sci. 1991, 88, 8237-8241.
-
(1991)
Proc. Natl. Acad. Sci.
, vol.88
, pp. 8237-8241
-
-
Pontius, B.W.1
Berg, P.2
-
13
-
-
0017108645
-
Deoxyribonucleic acid polymerase from the extreme thermophile thermus aquaticus
-
Chien, A.; Edgar, D.B.; Trela, J.M. Deoxyribonucleic acid polymerase from the extreme thermophile thermus aquaticus. J. Bacteriol. 1976, 127, 1550-1557.
-
(1976)
J. Bacteriol.
, vol.127
, pp. 1550-1557
-
-
Chien, A.1
Edgar, D.B.2
Trela, J.M.3
-
14
-
-
0006963422
-
13. Nucleotides. Part x. Some observations on the structure and chemical behaviour of the nucleic acids
-
Brown, D.M.; Todd, A.R. 13. Nucleotides. Part x. Some observations on the structure and chemical behaviour of the nucleic acids. J. Chem. Soc. (Resumed) 1952, 52-58.
-
(1952)
J. Chem. Soc. (Resumed)
, pp. 52-58
-
-
Brown, D.M.1
Todd, A.R.2
-
15
-
-
49149135789
-
Deoxynucleoside phosphoramidites-A new class of key intermediates for deoxypolynucleotide synthesis
-
Beaucage, S.L.; Caruthers, M.H. Deoxynucleoside phosphoramidites-A new class of key intermediates for deoxypolynucleotide synthesis. Tetrahedron Lett. 1981, 22, 1859-1862.
-
(1981)
Tetrahedron Lett.
, vol.22
, pp. 1859-1862
-
-
Beaucage, S.L.1
Caruthers, M.H.2
-
16
-
-
27844454796
-
Oligo- and poly-nucleotides: 50 years of chemical synthesis
-
Reese, C.B. Oligo- and poly-nucleotides: 50 years of chemical synthesis. Org. Biomol. Chem. 2005, 3, 3851-3868.
-
(2005)
Org. Biomol. Chem.
, vol.3
, pp. 3851-3868
-
-
Reese, C.B.1
-
17
-
-
0001120760
-
Preorganization of DNA: Design principles for improving nucleic acid recognition by synthetic oligonucleotides
-
Kool, E.T. Preorganization of DNA: Design principles for improving nucleic acid recognition by synthetic oligonucleotides. Chem. Rev. 1997, 97, 1473-1488.
-
(1997)
Chem. Rev.
, vol.97
, pp. 1473-1488
-
-
Kool, E.T.1
-
18
-
-
0034085537
-
Oligonucleotides functionalized by fluorescein and rhodamine dyes: Michael addition of methyl acrylate to 2′-deoxypseudouridine
-
Ramzaeva, N.; Rosemeyer, H.; Leonard, P.; Mühlegger, K.; Bergmann, F.; von der Eltz, H.; Seela, F. Oligonucleotides functionalized by fluorescein and rhodamine dyes: Michael addition of methyl acrylate to 2′-deoxypseudouridine. Helv. Chim. Acta 2000, 83, 1108-1126.
-
(2000)
Helv. Chim. Acta
, vol.83
, pp. 1108-1126
-
-
Ramzaeva, N.1
Rosemeyer, H.2
Leonard, P.3
Mühlegger, K.4
Bergmann, F.5
von der Eltz, H.6
Seela, F.7
-
19
-
-
0033799686
-
Preparation and applications of peptide-oligonucleotide conjugates
-
Tung, C.-H.; Stein, S. Preparation and applications of peptide-oligonucleotide conjugates. Bioconjugate Chem. 2000, 11, 605-618.
-
(2000)
Bioconjugate Chem.
, vol.11
, pp. 605-618
-
-
Tung, C.-H.1
Stein, S.2
-
20
-
-
84940190405
-
Synthesis of peptide-oligonucleotide conjugates using a heterobifunctional crosslinker
-
John Wiley & Sons, Inc.: Hoboken, NJ, USA
-
Williams, B.A.R.; Chaput, J.C. Synthesis of peptide-oligonucleotide conjugates using a heterobifunctional crosslinker. In Current Protocols in Nucleic Acid Chemistry; John Wiley & Sons, Inc.: Hoboken, NJ, USA, 2001.
-
(2001)
Current Protocols in Nucleic Acid Chemistry
-
-
Williams, B.A.R.1
Chaput, J.C.2
-
21
-
-
0036708090
-
The developments of semisynthetic DNA-protein conjugates
-
Niemeyer, C.M. The developments of semisynthetic DNA-protein conjugates. Trends Biotechnol. 2002, 20, 395-401.
-
(2002)
Trends Biotechnol.
, vol.20
, pp. 395-401
-
-
Niemeyer, C.M.1
-
22
-
-
0038719822
-
Synthesis, thermal stability and resistance to enzymatic hydrolysis of the oligonucleotides containing 5-(n-aminohexyl)carbamoyl-2′-o-methyluridines
-
Ito, T.; Ueno, Y.; Komatsu, Y.; Matsuda, A. Synthesis, thermal stability and resistance to enzymatic hydrolysis of the oligonucleotides containing 5-(n-aminohexyl)carbamoyl-2′-o-methyluridines. Nucleic Acids Res. 2003, 31, 2514-2523.
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 2514-2523
-
-
Ito, T.1
Ueno, Y.2
Komatsu, Y.3
Matsuda, A.4
-
23
-
-
0141792980
-
Aminomodified nucleobases: Functionalized nucleoside triphosphates applicable for selex
-
Schoetzau, T.; Langner, J.; Moyroud, E.; Roehl, I.; Vonhoff, S.; Klussmann, S. Aminomodified nucleobases: Functionalized nucleoside triphosphates applicable for selex. Bioconjugate Chem. 2003, 14, 919-926.
-
(2003)
Bioconjugate Chem.
, vol.14
, pp. 919-926
-
-
Schoetzau, T.1
Langner, J.2
Moyroud, E.3
Roehl, I.4
Vonhoff, S.5
Klussmann, S.6
-
24
-
-
47749138171
-
Peptide-oligonucleotide conjugates form stable and selective complexes with antibody and DNA
-
Tennilä, T.; Antopolsky, M.; Azhayev, A.; Azhayeva, E. Peptide-oligonucleotide conjugates form stable and selective complexes with antibody and DNA. Bioconjugate Chem. 2008, 19, 1361-1367.
-
(2008)
Bioconjugate Chem.
, vol.19
, pp. 1361-1367
-
-
Tennilä, T.1
Antopolsky, M.2
Azhayev, A.3
Azhayeva, E.4
-
25
-
-
64149129563
-
Analytical ancestry: "Firsts" in fluorescent labeling of nucleosides, nucleotides, and nucleic acids
-
Kricka, L.J.; Fortina, P. Analytical ancestry: "Firsts" in fluorescent labeling of nucleosides, nucleotides, and nucleic acids. Clin. Chem. 2009, 55, 670-683.
-
(2009)
Clin. Chem.
, vol.55
, pp. 670-683
-
-
Kricka, L.J.1
Fortina, P.2
-
26
-
-
0028806048
-
Quantitative monitoring of gene expression patterns with a complementary DNA microarray
-
Schena, M.; Shalon, D.; Davis, R.W.; Brown, P.O. Quantitative monitoring of gene expression patterns with a complementary DNA microarray. Science 1995, 270, 467-470.
-
(1995)
Science
, vol.270
, pp. 467-470
-
-
Schena, M.1
Shalon, D.2
Davis, R.W.3
Brown, P.O.4
-
27
-
-
0037090917
-
How to make a DNA chip
-
Pirrung, M.C. How to make a DNA chip. Angew. Chem. Int. Ed. 2002, 41, 1276-1289.
-
(2002)
Angew. Chem. Int. Ed.
, vol.41
, pp. 1276-1289
-
-
Pirrung, M.C.1
-
28
-
-
38749089860
-
DNA biosensors and microarrays
-
Sassolas, A.; Leca-Bouvier, B.D.; Blum, L.J. DNA biosensors and microarrays. Chem. Rev. 2008, 108, 109-139.
-
(2008)
Chem. Rev.
, vol.108
, pp. 109-139
-
-
Sassolas, A.1
Leca-Bouvier, B.D.2
Blum, L.J.3
-
29
-
-
80054734947
-
Magnetic bead-based multiplex DNA sequence detection of genetically modified organisms using quantum dot-encoded silicon dioxide nanoparticles
-
Zhao, Y.; Hao, C.; Ma, W.; Yong, Q.; Yan, W.; Kuang, H.; Wang, L.; Xu, C. Magnetic bead-based multiplex DNA sequence detection of genetically modified organisms using quantum dot-encoded silicon dioxide nanoparticles. J. Phys. Chem. C 2011, 115, 20134-20140.
-
(2011)
J. Phys. Chem. C
, vol.115
, pp. 20134-20140
-
-
Zhao, Y.1
Hao, C.2
Ma, W.3
Yong, Q.4
Yan, W.5
Kuang, H.6
Wang, L.7
Xu, C.8
-
30
-
-
0034802897
-
Intramers as promising new tools in functional proteomics
-
Famulok, M.; Blind, M.; Mayer, G. Intramers as promising new tools in functional proteomics. Chem. Biol. 2001, 8, 931-939.
-
(2001)
Chem. Biol.
, vol.8
, pp. 931-939
-
-
Famulok, M.1
Blind, M.2
Mayer, G.3
-
31
-
-
0042569528
-
Expressing RNA aptamers inside cells to reveal proteome and ribonome function
-
Burke, D.H.; Nickens, D.G. Expressing RNA aptamers inside cells to reveal proteome and ribonome function. Brief. Funct. Genomics Proteomics 2002, 1, 169-188.
-
(2002)
Brief. Funct. Genomics Proteomics
, vol.1
, pp. 169-188
-
-
Burke, D.H.1
Nickens, D.G.2
-
32
-
-
0036843787
-
In vivo-applied functional RNAs as tools in proteomics and genomics research
-
Famulok, M.; Verma, S. In vivo-applied functional RNAs as tools in proteomics and genomics research. Trends Biotechnol. 2002, 20, 462-466.
-
(2002)
Trends Biotechnol.
, vol.20
, pp. 462-466
-
-
Famulok, M.1
Verma, S.2
-
33
-
-
33749557373
-
Intracellular expression of the t-cell factor-1 rna aptamer as an intramer
-
Choi, K.H.; Park, M.W.; Lee, S.Y.; Jeon, M.-Y.; Kim, M.Y.; Lee, H.K.; Yu, J.; Kim, H.-J.; Han, K.; Lee, H.; et al. Intracellular expression of the t-cell factor-1 rna aptamer as an intramer. Mol. Cancer Ther. 2006, 5, 2428-2434.
-
(2006)
Mol. Cancer Ther.
, vol.5
, pp. 2428-2434
-
-
Choi, K.H.1
Park, M.W.2
Lee, S.Y.3
Jeon, M.-Y.4
Kim, M.Y.5
Lee, H.K.6
Yu, J.7
Kim, H.-J.8
Han, K.9
Lee, H.10
-
34
-
-
70349499011
-
Modulation of transcription by the peroxisome proliferator-activated receptor δ-binding RNA aptamer in colon cancer cells
-
Kwak, H.; Hwang, I.; Kim, J.H.; Kim, M.Y.; Yang, J.S.; Jeong, S. Modulation of transcription by the peroxisome proliferator-activated receptor δ-binding RNA aptamer in colon cancer cells. Mol. Cancer Ther. 2009, 8, 2664-2673.
-
(2009)
Mol. Cancer Ther.
, vol.8
, pp. 2664-2673
-
-
Kwak, H.1
Hwang, I.2
Kim, J.H.3
Kim, M.Y.4
Yang, J.S.5
Jeong, S.6
-
35
-
-
84864119483
-
Hybridoma technology for the generation of monoclonal antibodies
-
Proetzel, G., Ebersbach, H., Eds.; Humana Press: New York, NY, USA
-
Zhang, C. Hybridoma technology for the generation of monoclonal antibodies. In Antibody Methods and Protocols; Proetzel, G., Ebersbach, H., Eds.; Humana Press: New York, NY, USA, 2012; Volume 901, pp. 117-135.
-
(2012)
Antibody Methods and Protocols
, vol.901
, pp. 117-135
-
-
Zhang, C.1
-
36
-
-
84912535227
-
Mammalian cell display technology coupling with aid induced shm in vitro: An ideal approach to the production of therapeutic antibodies
-
Qin, C.-F.; Li, G.-C. Mammalian cell display technology coupling with aid induced shm in vitro: An ideal approach to the production of therapeutic antibodies. Int. Immunopharmacol. 2014, 23, 380-386.
-
(2014)
Int. Immunopharmacol.
, vol.23
, pp. 380-386
-
-
Qin, C.-F.1
Li, G.-C.2
-
37
-
-
0027180473
-
An rna motif that binds ATP
-
Sassanfar, M.; Szostak, J.W. An rna motif that binds ATP. Nature 1993, 364, 550-553.
-
(1993)
Nature
, vol.364
, pp. 550-553
-
-
Sassanfar, M.1
Szostak, J.W.2
-
38
-
-
0030878053
-
In vitro selection of dopamine RNA ligands
-
Mannironi, C.; di Nardo, A.; Fruscoloni, P.; Tocchini-Valentini, G.P. In vitro selection of dopamine RNA ligands. Biochemistry 1997, 36, 9726-9734.
-
(1997)
Biochemistry
, vol.36
, pp. 9726-9734
-
-
Mannironi, C.1
di Nardo, A.2
Fruscoloni, P.3
Tocchini-Valentini, G.P.4
-
39
-
-
0032539924
-
High affinity ligands from in vitro selection: Complex targets
-
Morris, K.N.; Jensen, K.B.; Julin, C.M.; Weil, M.; Gold, L. High affinity ligands from in vitro selection: Complex targets. Proc. Natl. Acad. Sci. USA 1998, 95, 2902-2907.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 2902-2907
-
-
Morris, K.N.1
Jensen, K.B.2
Julin, C.M.3
Weil, M.4
Gold, L.5
-
40
-
-
0035844150
-
Systematic evolution of a DNA aptamer binding to rat brain tumor microvessels: Selective targeting of endothelial regulatory protein pigpen
-
Blank, M.; Weinschenk, T.; Priemer, M.; Schluesener, H. Systematic evolution of a DNA aptamer binding to rat brain tumor microvessels: Selective targeting of endothelial regulatory protein pigpen. J. Biol. Chem. 2001, 276, 16464-16468.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 16464-16468
-
-
Blank, M.1
Weinschenk, T.2
Priemer, M.3
Schluesener, H.4
-
41
-
-
0347364648
-
A tenascin-c aptamer identified by tumor cell selex: Systematic evolution of ligands by exponential enrichment
-
Daniels, D.A.; Chen, H.; Hicke, B.J.; Swiderek, K.M.; Gold, L. A tenascin-c aptamer identified by tumor cell selex: Systematic evolution of ligands by exponential enrichment. Proc. Natl. Acad. Sci. USA 2003, 100, 15416-15421.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 15416-15421
-
-
Daniels, D.A.1
Chen, H.2
Hicke, B.J.3
Swiderek, K.M.4
Gold, L.5
-
42
-
-
0037430933
-
Single-stranded DNA aptamers that bind differentiated but not parental cells: Subtractive systematic evolution of ligands by exponential enrichment
-
Wang, C.; Zhang, M.; Yang, G.; Zhang, D.; Ding, H.; Wang, H.; Fan, M.; Shen, B.; Shao, N. Single-stranded DNA aptamers that bind differentiated but not parental cells: Subtractive systematic evolution of ligands by exponential enrichment. J. Biotechnol. 2003, 102, 15-22.
-
(2003)
J. Biotechnol.
, vol.102
, pp. 15-22
-
-
Wang, C.1
Zhang, M.2
Yang, G.3
Zhang, D.4
Ding, H.5
Wang, H.6
Fan, M.7
Shen, B.8
Shao, N.9
-
43
-
-
33746435294
-
Selection of DNA ligands for protein kinase c-[small delta]
-
Mallikaratchy, P.; Stahelin, R.V.; Cao, Z.; Cho, W.; Tan, W. Selection of DNA ligands for protein kinase c-[small delta]. Chem. Commun. 2006, 3229-3231.
-
(2006)
Chem. Commun.
, pp. 3229-3231
-
-
Mallikaratchy, P.1
Stahelin, R.V.2
Cao, Z.3
Cho, W.4
Tan, W.5
-
44
-
-
34447316180
-
Selection of aptamers for molecular recognition and characterization of cancer cells
-
Tang, Z.; Shangguan, D.; Wang, K.; Shi, H.; Sefah, K.; Mallikratchy, P.; Chen, H.W.; Li, Y.; Tan, W. Selection of aptamers for molecular recognition and characterization of cancer cells. Anal. Chem. 2007, 79, 4900-4907.
-
(2007)
Anal. Chem.
, vol.79
, pp. 4900-4907
-
-
Tang, Z.1
Shangguan, D.2
Wang, K.3
Shi, H.4
Sefah, K.5
Mallikratchy, P.6
Chen, H.W.7
Li, Y.8
Tan, W.9
-
45
-
-
46049096465
-
Molecular recognition of small-cell lung cancer cells using aptamers
-
Chen, H.W.; Medley, C.D.; Sefah, K.; Shangguan, D.; Tang, Z.; Meng, L.; Smith, J.E.; Tan, W. Molecular recognition of small-cell lung cancer cells using aptamers. ChemMedChem 2008, 3, 991-1001.
-
(2008)
ChemMedChem
, vol.3
, pp. 991-1001
-
-
Chen, H.W.1
Medley, C.D.2
Sefah, K.3
Shangguan, D.4
Tang, Z.5
Meng, L.6
Smith, J.E.7
Tan, W.8
-
46
-
-
60149090182
-
Molecular recognition of acute myeloid leukemia using aptamers
-
Sefah, K.; Tang, Z.W.; Shangguan, D.H.; Chen, H.; Lopez-Colon, D.; Li, Y.; Parekh, P.; Martin, J.; Meng, L.; Phillips, J.A.; et al. Molecular recognition of acute myeloid leukemia using aptamers. Leukemia 2009, 23, 235-244.
-
(2009)
Leukemia
, vol.23
, pp. 235-244
-
-
Sefah, K.1
Tang, Z.W.2
Shangguan, D.H.3
Chen, H.4
Lopez-Colon, D.5
Li, Y.6
Parekh, P.7
Martin, J.8
Meng, L.9
Phillips, J.A.10
-
47
-
-
64149094557
-
Generating aptamers for recognition of virus-infected cells
-
Tang, Z.; Parekh, P.; Turner, P.; Moyer, R.W.; Tan, W. Generating aptamers for recognition of virus-infected cells. Clin. Chem. 2009, 55, 813-822.
-
(2009)
Clin. Chem.
, vol.55
, pp. 813-822
-
-
Tang, Z.1
Parekh, P.2
Turner, P.3
Moyer, R.W.4
Tan, W.5
-
48
-
-
66249129385
-
Selection, characterization and application of new RNA HIV GP 120 aptamers for facile delivery of dicer substrate sirnas into hiv infected cells
-
Zhou, J.; Swiderski, P.; Li, H.; Zhang, J.; Neff, C.P.; Akkina, R.; Rossi, J.J. Selection, characterization and application of new RNA HIV GP 120 aptamers for facile delivery of dicer substrate sirnas into hiv infected cells. Nucleic Acids Res. 2009, 37, 3094-3109.
-
(2009)
Nucleic Acids Res.
, vol.37
, pp. 3094-3109
-
-
Zhou, J.1
Swiderski, P.2
Li, H.3
Zhang, J.4
Neff, C.P.5
Akkina, R.6
Rossi, J.J.7
-
49
-
-
74049140005
-
In vivo selection of tumor-targeting RNA motifs
-
Mi, J.; Liu, Y.; Rabbani, Z.N.; Yang, Z.; Urban, J.H.; Sullenger, B.A.; Clary, B.M. In vivo selection of tumor-targeting RNA motifs. Nat. Chem. Biol. 2010, 6, 22-24.
-
(2010)
Nat. Chem. Biol.
, vol.6
, pp. 22-24
-
-
Mi, J.1
Liu, Y.2
Rabbani, Z.N.3
Yang, Z.4
Urban, J.H.5
Sullenger, B.A.6
Clary, B.M.7
-
50
-
-
77958024214
-
Aptamers recognizing glycosylated hemagglutinin expressed on the surface of vaccinia virus-infected cells
-
Parekh, P.; Tang, Z.; Turner, P.C.; Moyer, R.W.; Tan, W. Aptamers recognizing glycosylated hemagglutinin expressed on the surface of vaccinia virus-infected cells. Anal. Chem. 2010, 82, 8642-8649.
-
(2010)
Anal. Chem.
, vol.82
, pp. 8642-8649
-
-
Parekh, P.1
Tang, Z.2
Turner, P.C.3
Moyer, R.W.4
Tan, W.5
-
51
-
-
79952786273
-
In vitro selection of DNA aptamers to glioblastoma multiforme
-
Bayrac, A.T.; Sefah, K.; Parekh, P.; Bayrac, C.; Gulbakan, B.; Oktem, H.A.; Tan, W. In vitro selection of DNA aptamers to glioblastoma multiforme. ACS Chem. Neurosci. 2011, 2, 175-181.
-
(2011)
ACS Chem. Neurosci.
, vol.2
, pp. 175-181
-
-
Bayrac, A.T.1
Sefah, K.2
Parekh, P.3
Bayrac, C.4
Gulbakan, B.5
Oktem, H.A.6
Tan, W.7
-
52
-
-
79551701139
-
Bioresponsive controlled release using mesoporous silica nanoparticles capped with aptamer-based molecular gate
-
Zhu, C.-L.; Lu, C.-H.; Song, X.-Y.; Yang, H.-H.; Wang, X.-R. Bioresponsive controlled release using mesoporous silica nanoparticles capped with aptamer-based molecular gate. J. Am. Chem. Soc. 2011, 133, 1278-1281.
-
(2011)
J. Am. Chem. Soc.
, vol.133
, pp. 1278-1281
-
-
Zhu, C.-L.1
Lu, C.-H.2
Song, X.-Y.3
Yang, H.-H.4
Wang, X.-R.5
-
53
-
-
84865703131
-
ATP-responsive controlled release system using aptamer-functionalized mesoporous silica nanoparticles
-
He, X.; Zhao, Y.; He, D.; Wang, K.; Xu, F.; Tang, J. ATP-responsive controlled release system using aptamer-functionalized mesoporous silica nanoparticles. Langmuir 2012, 28, 12909-12915.
-
(2012)
Langmuir
, vol.28
, pp. 12909-12915
-
-
He, X.1
Zhao, Y.2
He, D.3
Wang, K.4
Xu, F.5
Tang, J.6
-
54
-
-
84884601713
-
Aptamer-conjugated nanorods for targeted photothermal therapy of prostate cancer stem cells
-
Wang, J.; Sefah, K.; Altman, M.B.; Chen, T.; You, M.; Zhao, Z.; Huang, C.Z.; Tan, W. Aptamer-conjugated nanorods for targeted photothermal therapy of prostate cancer stem cells. Chem.-Asian J. 2013, 8, 2417-2422.
-
(2013)
Chem.-Asian J.
, vol.8
, pp. 2417-2422
-
-
Wang, J.1
Sefah, K.2
Altman, M.B.3
Chen, T.4
You, M.5
Zhao, Z.6
Huang, C.Z.7
Tan, W.8
-
55
-
-
0029938209
-
Potent antisense oligonucleotides to the human multidrug resistance-1 mRNA are rationally selected by mapping rna-accessible sites with oligonucleotide libraries
-
Peng Ho, S.; Britton, D.H.O.; Stone, B.A.; Behrens, D.L.; Leffet, L.M.; Hobbs, F.W.; Miller, J.A.; Trainor, G.L. Potent antisense oligonucleotides to the human multidrug resistance-1 mRNA are rationally selected by mapping rna-accessible sites with oligonucleotide libraries. Nucleic Acids Res. 1996, 24, 1901-1907.
-
(1996)
Nucleic Acids Res.
, vol.24
, pp. 1901-1907
-
-
Peng Ho, S.1
Britton, D.H.O.2
Stone, B.A.3
Behrens, D.L.4
Leffet, L.M.5
Hobbs, F.W.6
Miller, J.A.7
Trainor, G.L.8
-
56
-
-
52449123115
-
Selecting aptamers for a glycoprotein through the incorporation of the boronic acid moiety
-
Li, M.; Lin, N.; Huang, Z.; Du, L.; Altier, C.; Fang, H.; Wang, B. Selecting aptamers for a glycoprotein through the incorporation of the boronic acid moiety. J. Am. Chem. Soc. 2008, 130, 12636-12638.
-
(2008)
J. Am. Chem. Soc.
, vol.130
, pp. 12636-12638
-
-
Li, M.1
Lin, N.2
Huang, Z.3
Du, L.4
Altier, C.5
Fang, H.6
Wang, B.7
-
57
-
-
1342279558
-
Sialyllactose-binding modified DNA aptamer bearing additional functionality by selex
-
Mehedi Masud, M.; Kuwahara, M.; Ozaki, H.; Sawai, H. Sialyllactose-binding modified DNA aptamer bearing additional functionality by selex. Bioorg. Med. Chem. 2004, 12, 1111-1120.
-
(2004)
Bioorg. Med. Chem.
, vol.12
, pp. 1111-1120
-
-
Mehedi Masud, M.1
Kuwahara, M.2
Ozaki, H.3
Sawai, H.4
-
58
-
-
0344213748
-
Chemically modified nucleic acid aptamers for in vitro selections: Evolving evolution
-
Kusser, W. Chemically modified nucleic acid aptamers for in vitro selections: Evolving evolution. Rev. Mol. Biotechnol. 2000, 74, 27-38.
-
(2000)
Rev. Mol. Biotechnol.
, vol.74
, pp. 27-38
-
-
Kusser, W.1
-
60
-
-
0031012128
-
Potent 2[prime]-amino-, and 2[prime]-fluoro-2[prime]- deoxyribonucleotide RNA inhibitors of keratinocyte growth factor
-
Pagratis, N.C.; Bell, C.; Chang, Y.-F.; Jennings, S.; Fitzwater, T.; Jellinek, D.; Dang, C. Potent 2[prime]-amino-, and 2[prime]-fluoro-2[prime]- deoxyribonucleotide RNA inhibitors of keratinocyte growth factor. Nat. Biotechnol. 1997, 15, 68-73.
-
(1997)
Nat. Biotechnol.
, vol.15
, pp. 68-73
-
-
Pagratis, N.C.1
Bell, C.2
Chang, Y.-F.3
Jennings, S.4
Fitzwater, T.5
Jellinek, D.6
Dang, C.7
-
61
-
-
84940189654
-
Progress in chemically modified nucleic acid aptamers
-
Erdmann, V.A., Markiewicz, W.T., Barciszewski, J., Eds.; Springer Berlin Heidelberg: Berlin, Germany
-
Kuwahara, M. Progress in chemically modified nucleic acid aptamers. In Chemical Biology of Nucleic Acids; Erdmann, V.A., Markiewicz, W.T., Barciszewski, J., Eds.; Springer Berlin Heidelberg: Berlin, Germany, 2014; pp. 243-270.
-
(2014)
Chemical Biology of Nucleic Acids
, pp. 243-270
-
-
Kuwahara, M.1
-
62
-
-
0029758369
-
Mirror-image RNA that binds d-adenosine
-
Kluszmann, S.; Nolte, A.; Bald, R.; Erdmann, V.A.; Furste, J.P. Mirror-image RNA that binds d-adenosine. Nat. Biotechnol. 1996, 14, 1112-1115.
-
(1996)
Nat. Biotechnol.
, vol.14
, pp. 1112-1115
-
-
Kluszmann, S.1
Nolte, A.2
Bald, R.3
Erdmann, V.A.4
Furste, J.P.5
-
63
-
-
0142043453
-
Spiegelmers: Biostable aptamers
-
Eulberg, D.; Klussmann, S. Spiegelmers: Biostable aptamers. ChemBioChem 2003, 4, 979-983.
-
(2003)
ChemBioChem
, vol.4
, pp. 979-983
-
-
Eulberg, D.1
Klussmann, S.2
-
64
-
-
84922431782
-
Turning mirror-image oligonucleotides into drugs: The evolution of spiegelmer® therapeutics
-
Vater, A.; Klussmann, S. Turning mirror-image oligonucleotides into drugs: The evolution of spiegelmer® therapeutics. Drug Discov. Today 2015, 20, 147-155.
-
(2015)
Drug Discov. Today
, vol.20
, pp. 147-155
-
-
Vater, A.1
Klussmann, S.2
-
66
-
-
27644558626
-
Combining selex with quantitative assays to rapidly obtain accurate models of protein-DNA interactions
-
Liu, J.; Stormo, G.D. Combining selex with quantitative assays to rapidly obtain accurate models of protein-DNA interactions. Nucleic Acids Res. 2005, 33, doi: 10.1093/nar/gni139.
-
(2005)
Nucleic Acids Res.
, vol.33
-
-
Liu, J.1
Stormo, G.D.2
-
67
-
-
23944515324
-
Aptamer-based biosensors for the detection of HIV-1 Tat protein
-
Tombelli, S.; Minunni, M.; Luzi, E.; Mascini, M. Aptamer-based biosensors for the detection of HIV-1 Tat protein. Bioelectrochemistry 2005, 67, 135-141.
-
(2005)
Bioelectrochemistry
, vol.67
, pp. 135-141
-
-
Tombelli, S.1
Minunni, M.2
Luzi, E.3
Mascini, M.4
-
68
-
-
26644468823
-
Development of an automated in vitro selection protocol to obtain rna-based aptamers: Identification of a biostable substance p antagonist
-
Eulberg, D.; Buchner, K.; Maasch, C.; Klussmann, S. Development of an automated in vitro selection protocol to obtain rna-based aptamers: Identification of a biostable substance p antagonist. Nucleic Acids Res. 2005, 33, e45.
-
(2005)
Nucleic Acids Res.
, vol.33
-
-
Eulberg, D.1
Buchner, K.2
Maasch, C.3
Klussmann, S.4
-
69
-
-
33845679081
-
Methods developed for selex
-
Gopinath, S. Methods developed for selex. Anal. Bioanal. Chem. 2007, 387, 171-182.
-
(2007)
Anal. Bioanal. Chem.
, vol.387
, pp. 171-182
-
-
Gopinath, S.1
-
70
-
-
67650088525
-
Identification of an aptamer targeting hnRNP a1 by tissue slide-based selex
-
Li, S.; Xu, H.; Ding, H.; Huang, Y.; Cao, X.; Yang, G.; Li, J.; Xie, Z.; Meng, Y.; Li, X.; et al. Identification of an aptamer targeting hnRNP a1 by tissue slide-based selex. J. Pathol. 2009, 218, 327-336.
-
(2009)
J. Pathol.
, vol.218
, pp. 327-336
-
-
Li, S.1
Xu, H.2
Ding, H.3
Huang, Y.4
Cao, X.5
Yang, G.6
Li, J.7
Xie, Z.8
Meng, Y.9
Li, X.10
-
71
-
-
0028869690
-
Diversity of oligonucleotide functions
-
Gold, L.; Polisky, B.; Uhlenbeck, O.; Yarus, M. Diversity of oligonucleotide functions. Annu. Rev. Biochem. 1995, 64, 763-797.
-
(1995)
Annu. Rev. Biochem.
, vol.64
, pp. 763-797
-
-
Gold, L.1
Polisky, B.2
Uhlenbeck, O.3
Yarus, M.4
-
72
-
-
0032860385
-
Aptamers: An emerging class of molecules that rival antibodies in diagnostics
-
Jayasena, S.D. Aptamers: An emerging class of molecules that rival antibodies in diagnostics. Clin. Chem. 1999, 45, 1628-1650.
-
(1999)
Clin. Chem.
, vol.45
, pp. 1628-1650
-
-
Jayasena, S.D.1
-
73
-
-
78650917894
-
Structural prediction and binding analysis of hybridized aptamers
-
Zhou, J.; Soontornworajit, B.; Snipes, M.P.; Wang, Y. Structural prediction and binding analysis of hybridized aptamers. J. Mol. Recognit. 2011, 24, 119-126.
-
(2011)
J. Mol. Recognit.
, vol.24
, pp. 119-126
-
-
Zhou, J.1
Soontornworajit, B.2
Snipes, M.P.3
Wang, Y.4
-
74
-
-
0042121256
-
Mfold web server for nucleic acid folding and hybridization prediction
-
Zuker, M. Mfold web server for nucleic acid folding and hybridization prediction. Nucleic Acids Res. 2003, 31, 3406-3415.
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 3406-3415
-
-
Zuker, M.1
-
75
-
-
34250309191
-
Optimization and modifications of aptamers selected from live cancer cell lines
-
Shangguan, D.; Tang, Z.; Mallikaratchy, P.; Xiao, Z.; Tan, W. Optimization and modifications of aptamers selected from live cancer cell lines. ChemBioChem 2007, 8, 603-606.
-
(2007)
ChemBioChem
, vol.8
, pp. 603-606
-
-
Shangguan, D.1
Tang, Z.2
Mallikaratchy, P.3
Xiao, Z.4
Tan, W.5
-
76
-
-
78650191633
-
Aptamer-based molecular recognition for biosensor development
-
Zhou, J.; Battig, M.; Wang, Y. Aptamer-based molecular recognition for biosensor development. Anal. Bioanal. Chem. 2010, 398, 2471-2480.
-
(2010)
Anal. Bioanal. Chem.
, vol.398
, pp. 2471-2480
-
-
Zhou, J.1
Battig, M.2
Wang, Y.3
-
77
-
-
80054730117
-
Rational truncation of an rna aptamer to prostate-specific membrane antigen using computational structural modeling
-
Rockey, W.M.; Hernandez, F.J.; Huang, S.-Y.; Cao, S.; Howell, C.A.; Thomas, G.S.; Liu, X.Y.; Lapteva, N.; Spencer, D.M.; McNamara, J.O.; et al. Rational truncation of an rna aptamer to prostate-specific membrane antigen using computational structural modeling. Nucleic Acid Ther. 2011, 21, 299-314.
-
(2011)
Nucleic Acid Ther.
, vol.21
, pp. 299-314
-
-
Rockey, W.M.1
Hernandez, F.J.2
Huang, S.-Y.3
Cao, S.4
Howell, C.A.5
Thomas, G.S.6
Liu, X.Y.7
Lapteva, N.8
Spencer, D.M.9
McNamara, J.O.10
-
78
-
-
84896996881
-
Chemically modified DNA aptamers bind interleukin-6 with high affinity and inhibit signaling by blocking its interaction with interleukin-6 receptor
-
Gupta, S.; Hirota, M.; Waugh, S.M.; Murakami, I.; Suzuki, T.; Muraguchi, M.; Shibamori, M.; Ishikawa, Y.; Jarvis, T.C.; Carter, J.D.; et al. Chemically modified DNA aptamers bind interleukin-6 with high affinity and inhibit signaling by blocking its interaction with interleukin-6 receptor. J. Biol. Chem. 2014, 289, 8706-8719.
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 8706-8719
-
-
Gupta, S.1
Hirota, M.2
Waugh, S.M.3
Murakami, I.4
Suzuki, T.5
Muraguchi, M.6
Shibamori, M.7
Ishikawa, Y.8
Jarvis, T.C.9
Carter, J.D.10
-
79
-
-
84979862091
-
RNAPattMatch: A web server for RNA sequence/structure motif detection based on pattern matching with flexible gaps
-
Drory Retwitzer, M.; Polishchuk, M.; Churkin, E.; Kifer, I.; Yakhini, Z.; Barash, D. RNAPattMatch: A web server for RNA sequence/structure motif detection based on pattern matching with flexible gaps. Nucleic Acids Res. 2015, 43, doi: 10.1093/nar/gkv435.
-
(2015)
Nucleic Acids Res.
, vol.43
-
-
Drory Retwitzer, M.1
Polishchuk, M.2
Churkin, E.3
Kifer, I.4
Yakhini, Z.5
Barash, D.6
-
80
-
-
84928814984
-
Neutralization of staphylococcal enterotoxin b by an aptamer antagonist
-
Wang, K.; Gan, L.; Jiang, L.; Zhang, X.; Yang, X.; Chen, M.; Lan, X. Neutralization of staphylococcal enterotoxin b by an aptamer antagonist. Antimicrob. Agents Chemother. 2015, 59, 2072-2077.
-
(2015)
Antimicrob. Agents Chemother.
, vol.59
, pp. 2072-2077
-
-
Wang, K.1
Gan, L.2
Jiang, L.3
Zhang, X.4
Yang, X.5
Chen, M.6
Lan, X.7
-
81
-
-
0029806701
-
Inhibitory DNA ligands to platelet-derived growth factor b-chain
-
Green, L.S.; Jellinek, D.; Jenison, R.; Östman, A.; Heldin, C.-H.; Janjic, N. Inhibitory DNA ligands to platelet-derived growth factor b-chain. Biochemistry 1996, 35, 14413-14424.
-
(1996)
Biochemistry
, vol.35
, pp. 14413-14424
-
-
Green, L.S.1
Jellinek, D.2
Jenison, R.3
Östman, A.4
Heldin, C.-H.5
Janjic, N.6
-
82
-
-
1842424691
-
Structural determinants of conformationally selective, prion-binding aptamers
-
Sayer, N.M.; Cubin, M.; Rhie, A.; Bullock, M.; Tahiri-Alaoui, A.; James, W. Structural determinants of conformationally selective, prion-binding aptamers. J. Biol. Chem. 2004, 279, 13102-13109.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 13102-13109
-
-
Sayer, N.M.1
Cubin, M.2
Rhie, A.3
Bullock, M.4
Tahiri-Alaoui, A.5
James, W.6
-
83
-
-
79958865003
-
Selection and characterization of DNA aptamers against prpsc
-
Wang, P.; Hatcher, K.L.; Bartz, J.C.; Chen, S.G.; Skinner, P.; Richt, J.; Liu, H.; Sreevatsan, S. Selection and characterization of DNA aptamers against prpsc. Exp. Biol. Med. 2011, 236, 466-476.
-
(2011)
Exp. Biol. Med.
, vol.236
, pp. 466-476
-
-
Wang, P.1
Hatcher, K.L.2
Bartz, J.C.3
Chen, S.G.4
Skinner, P.5
Richt, J.6
Liu, H.7
Sreevatsan, S.8
-
84
-
-
38049048268
-
Exploring the sequence space of a DNA aptamer using microarrays
-
Katilius, E.; Flores, C.; Woodbury, N.W. Exploring the sequence space of a DNA aptamer using microarrays. Nucleic Acids Res. 2007, 35, 7626-7635.
-
(2007)
Nucleic Acids Res.
, vol.35
, pp. 7626-7635
-
-
Katilius, E.1
Flores, C.2
Woodbury, N.W.3
-
85
-
-
84887445694
-
Quantitative selection and parallel characterization of aptamers
-
Cho, M.; Soo Oh, S.; Nie, J.; Stewart, R.; Eisenstein, M.; Chambers, J.; Marth, J.D.; Walker, F.; Thomson, J.A.; Soh, H.T. Quantitative selection and parallel characterization of aptamers. Proc. Natl. Acad. Sci. USA 2013, 110, 18460-18465.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 18460-18465
-
-
Cho, M.1
Soo Oh, S.2
Nie, J.3
Stewart, R.4
Eisenstein, M.5
Chambers, J.6
Marth, J.D.7
Walker, F.8
Thomson, J.A.9
Soh, H.T.10
-
86
-
-
84872847383
-
RNA aptamers targeting cancer stem cell marker cd133
-
Shigdar, S.; Qiao, L.; Zhou, S.-F.; Xiang, D.; Wang, T.; Li, Y.; Lim, L.Y.; Kong, L.; Li, L.; Duan, W. RNA aptamers targeting cancer stem cell marker cd133. Cancer Lett. 2013, 330, 84-95.
-
(2013)
Cancer Lett.
, vol.330
, pp. 84-95
-
-
Shigdar, S.1
Qiao, L.2
Zhou, S.-F.3
Xiang, D.4
Wang, T.5
Li, Y.6
Lim, L.Y.7
Kong, L.8
Li, L.9
Duan, W.10
-
88
-
-
40849147041
-
EGFR antagonists in cancer treatment
-
Ciardiello, F.; Tortora, G. EGFR antagonists in cancer treatment. New Engl. J. Med. 2008, 358, 1160-1174.
-
(2008)
New Engl. J. Med.
, vol.358
, pp. 1160-1174
-
-
Ciardiello, F.1
Tortora, G.2
-
89
-
-
84877854501
-
Aptamer to ErbB-2/HER2 enhances degradation of the target and inhibits tumorigenic growth
-
Mahlknecht, G.; Maron, R.; Mancini, M.; Schechter, B.; Sela, M.; Yarden, Y. Aptamer to ErbB-2/HER2 enhances degradation of the target and inhibits tumorigenic growth. Proc. Natl. Acad. Sci. USA 2013, 110, 8170-8175.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 8170-8175
-
-
Mahlknecht, G.1
Maron, R.2
Mancini, M.3
Schechter, B.4
Sela, M.5
Yarden, Y.6
-
90
-
-
0035313152
-
Therapeutic antibody expression technology
-
Chadd, H.E.; Chamow, S.M. Therapeutic antibody expression technology. Curr. Opin. Biotechnol. 2001, 12, 188-194.
-
(2001)
Curr. Opin. Biotechnol.
, vol.12
, pp. 188-194
-
-
Chadd, H.E.1
Chamow, S.M.2
-
91
-
-
34347395733
-
Trastuzumab-Mechanism of action and use in clinical practice
-
Hudis, C.A. Trastuzumab-Mechanism of action and use in clinical practice. New Engl. J. Med. 2007, 357, 39-51.
-
(2007)
New Engl. J. Med.
, vol.357
, pp. 39-51
-
-
Hudis, C.A.1
-
92
-
-
38349061033
-
Aptamer directly evolved from live cells recognizes membrane bound immunoglobin heavy mu chain in burkitt's lymphoma cells
-
Mallikaratchy, P.; Tang, Z.; Kwame, S.; Meng, L.; Shangguan, D.; Tan, W. Aptamer directly evolved from live cells recognizes membrane bound immunoglobin heavy mu chain in burkitt's lymphoma cells. Mol. Cell. Proteomics 2007, 6, 2230-2238.
-
(2007)
Mol. Cell. Proteomics
, vol.6
, pp. 2230-2238
-
-
Mallikaratchy, P.1
Tang, Z.2
Kwame, S.3
Meng, L.4
Shangguan, D.5
Tan, W.6
-
93
-
-
46049086644
-
Cell-specific aptamer probes for membrane protein elucidation in cancer cells
-
Shangguan, D.; Cao, Z.; Meng, L.; Mallikaratchy, P.; Sefah, K.; Wang, H.; Li, Y.; Tan, W. Cell-specific aptamer probes for membrane protein elucidation in cancer cells. J. Proteome Res. 2008, 7, 2133-2139.
-
(2008)
J. Proteome Res.
, vol.7
, pp. 2133-2139
-
-
Shangguan, D.1
Cao, Z.2
Meng, L.3
Mallikaratchy, P.4
Sefah, K.5
Wang, H.6
Li, Y.7
Tan, W.8
-
94
-
-
84899854183
-
Identification of cell membrane protein stress-induced phosphoprotein 1 as a potential ovarian cancer biomarker using aptamers selected by cell systematic evolution of ligands by exponential enrichment
-
Van Simaeys, D.; Turek, D.; Champanhac, C.; Vaizer, J.; Sefah, K.; Zhen, J.; Sutphen, R.; Tan, W. Identification of cell membrane protein stress-induced phosphoprotein 1 as a potential ovarian cancer biomarker using aptamers selected by cell systematic evolution of ligands by exponential enrichment. Anal. Chem. 2014, 86, 4521-4527.
-
(2014)
Anal. Chem.
, vol.86
, pp. 4521-4527
-
-
Van Simaeys, D.1
Turek, D.2
Champanhac, C.3
Vaizer, J.4
Sefah, K.5
Zhen, J.6
Sutphen, R.7
Tan, W.8
-
95
-
-
0029670262
-
Molecular beacons: Probes that fluoresce upon hybridization
-
Tyagi, S.; Kramer, F.R. Molecular beacons: Probes that fluoresce upon hybridization. Nat. Biotechnol. 1996, 14, 303-308.
-
(1996)
Nat. Biotechnol.
, vol.14
, pp. 303-308
-
-
Tyagi, S.1
Kramer, F.R.2
-
96
-
-
0034677706
-
Molecular beacons: A novel approach to detect protein-DNA interactions
-
Li, J.J.; Fang, X.; Schuster, S.M.; Tan, W. Molecular beacons: A novel approach to detect protein-DNA interactions. Angew. Chem. Int. Ed. 2000, 39, 1049-1052.
-
(2000)
Angew. Chem. Int. Ed.
, vol.39
, pp. 1049-1052
-
-
Li, J.J.1
Fang, X.2
Schuster, S.M.3
Tan, W.4
-
97
-
-
0035879386
-
Aptamer beacons for the direct detection of proteins
-
Hamaguchi, N.; Ellington, A.; Stanton, M. Aptamer beacons for the direct detection of proteins. Anal. Biochem. 2001, 294, 126-131.
-
(2001)
Anal. Biochem.
, vol.294
, pp. 126-131
-
-
Hamaguchi, N.1
Ellington, A.2
Stanton, M.3
-
98
-
-
0036297293
-
Molecular aptamer beacons for real-time protein recognition
-
Li, J.J.; Fang, X.; Tan, W. Molecular aptamer beacons for real-time protein recognition. Biochem. Biophys. Res. Commun. 2002, 292, 31-40.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.292
, pp. 31-40
-
-
Li, J.J.1
Fang, X.2
Tan, W.3
-
99
-
-
0037462083
-
Structure-switching signaling aptamers
-
Nutiu, R.; Li, Y. Structure-switching signaling aptamers. J. Am. Chem. Soc. 2003, 125, 4771-4778.
-
(2003)
J. Am. Chem. Soc.
, vol.125
, pp. 4771-4778
-
-
Nutiu, R.1
Li, Y.2
-
100
-
-
84936743191
-
Structure-switching aptamer triggering hybridization chain reaction on the cell surface for activatable theranostics
-
Wang, Y.-M.; Wu, Z.; Liu, S.-J.; Chu, X. Structure-switching aptamer triggering hybridization chain reaction on the cell surface for activatable theranostics. Anal. Chem. 2015, doi:10.1021/acs.analchem.5b01634.
-
(2015)
Anal. Chem.
-
-
Wang, Y.-M.1
Wu, Z.2
Liu, S.-J.3
Chu, X.4
-
101
-
-
33745610353
-
Quantum-dot aptamer beacons for the detection of proteins
-
Levy, M.; Cater, S.F.; Ellington, A.D. Quantum-dot aptamer beacons for the detection of proteins. ChemBioChem 2005, 6, 2163-2166.
-
(2005)
ChemBioChem
, vol.6
, pp. 2163-2166
-
-
Levy, M.1
Cater, S.F.2
Ellington, A.D.3
-
102
-
-
36248973801
-
Quantum dot-aptamer conjugates for synchronous cancer imaging, therapy, and sensing of drug delivery based on bi-fluorescence resonance energy transfer
-
Bagalkot, V.; Zhang, L.; Levy-Nissenbaum, E.; Jon, S.; Kantoff, P.W.; Langer, R.; Farokhzad, O.C. Quantum dot-aptamer conjugates for synchronous cancer imaging, therapy, and sensing of drug delivery based on bi-fluorescence resonance energy transfer. Nano Lett. 2007, 7, 3065-3070.
-
(2007)
Nano Lett.
, vol.7
, pp. 3065-3070
-
-
Bagalkot, V.1
Zhang, L.2
Levy-Nissenbaum, E.3
Jon, S.4
Kantoff, P.W.5
Langer, R.6
Farokhzad, O.C.7
-
103
-
-
84864384868
-
Quantum dot-nucleic acid/aptamer bioconjugate-based fluorimetric biosensors
-
Zhou, D. Quantum dot-nucleic acid/aptamer bioconjugate-based fluorimetric biosensors. Biochem. Soc. Trans. 2012, 40, 635-639.
-
(2012)
Biochem. Soc. Trans.
, vol.40
, pp. 635-639
-
-
Zhou, D.1
-
104
-
-
37649008898
-
Aptamer biosensor for protein detection using gold nanoparticles
-
Wang, W.; Chen, C.; Qian, M.; Zhao, X.S. Aptamer biosensor for protein detection using gold nanoparticles. Anal. Biochem. 2008, 373, 213-219.
-
(2008)
Anal. Biochem.
, vol.373
, pp. 213-219
-
-
Wang, W.1
Chen, C.2
Qian, M.3
Zhao, X.S.4
-
105
-
-
79958258087
-
Gold nanoparticle-based colorimetric detection of kanamycin using a DNA aptamer
-
Song, K.-M.; Cho, M.; Jo, H.; Min, K.; Jeon, S.H.; Kim, T.; Han, M.S.; Ku, J.K.; Ban, C. Gold nanoparticle-based colorimetric detection of kanamycin using a DNA aptamer. Anal. Biochem. 2011, 415, 175-181.
-
(2011)
Anal. Biochem.
, vol.415
, pp. 175-181
-
-
Song, K.-M.1
Cho, M.2
Jo, H.3
Min, K.4
Jeon, S.H.5
Kim, T.6
Han, M.S.7
Ku, J.K.8
Ban, C.9
-
106
-
-
84923165862
-
A gold nanoparticle-based label free colorimetric aptasensor for adenosine deaminase detection and inhibition assay
-
Cheng, F.; He, Y.; Xing, X.-J.; Tan, D.-D.; Lin, Y.; Pang, D.-W.; Tang, H.-W. A gold nanoparticle-based label free colorimetric aptasensor for adenosine deaminase detection and inhibition assay. Analyst 2015, 140, 1572-1577.
-
(2015)
Analyst
, vol.140
, pp. 1572-1577
-
-
Cheng, F.1
He, Y.2
Xing, X.-J.3
Tan, D.-D.4
Lin, Y.5
Pang, D.-W.6
Tang, H.-W.7
-
107
-
-
84866239681
-
A gold nanoparticles-modified aptamer beacon for urinary adenosine detection based on structureswitching/ fluorescence-"turning on" mechanism
-
Zhang, J.-Q.; Wang, Y.-S.; Xue, J.-H.; He, Y.; Yang, H.-X.; Liang, J.; Shi, L.-F.; Xiao, X.-L. A gold nanoparticles-modified aptamer beacon for urinary adenosine detection based on structureswitching/ fluorescence-"turning on" mechanism. J. Pharm. Biomed. Anal. 2012, 70, 362-368.
-
(2012)
J. Pharm. Biomed. Anal.
, vol.70
, pp. 362-368
-
-
Zhang, J.-Q.1
Wang, Y.-S.2
Xue, J.-H.3
He, Y.4
Yang, H.-X.5
Liang, J.6
Shi, L.-F.7
Xiao, X.-L.8
-
108
-
-
84939644100
-
Highly sensitive colorimetric detection of 17[bgr]-estradiol using split DNA aptamers immobilized on unmodified gold nanoparticles
-
Liu, J.; Bai, W.; Niu, S.; Zhu, C.; Yang, S.; Chen, A. Highly sensitive colorimetric detection of 17[bgr]-estradiol using split DNA aptamers immobilized on unmodified gold nanoparticles. Sci. Rep. 2014, 4.
-
(2014)
Sci. Rep.
, pp. 4
-
-
Liu, J.1
Bai, W.2
Niu, S.3
Zhu, C.4
Yang, S.5
Chen, A.6
-
109
-
-
84881368455
-
Immunological properties of an antibody containing a fluorescent group
-
Coons, A.H.; Creech, H.J.; Jones, R.N. Immunological properties of an antibody containing a fluorescent group. Exp. Biol. Med. 1941, 47, 200-202.
-
(1941)
Exp. Biol. Med.
, vol.47
, pp. 200-202
-
-
Coons, A.H.1
Creech, H.J.2
Jones, R.N.3
-
110
-
-
0015116634
-
Enzyme-linked immunosorbent assay (elisa) quantitative assay of immunoglobulin g
-
Engvall, E.; Perlmann, P. Enzyme-linked immunosorbent assay (elisa) quantitative assay of immunoglobulin g. Immunochemistry 1971, 8, 871-874.
-
(1971)
Immunochemistry
, vol.8
, pp. 871-874
-
-
Engvall, E.1
Perlmann, P.2
-
111
-
-
3242832518
-
Immunoassay using antigen-enzyme conjugates
-
Van Weemen, B.K.; Schuurs, A.H.W.M. Immunoassay using antigen-enzyme conjugates. FEBS Lett. 1971, 15, 232-236.
-
(1971)
FEBS Lett.
, vol.15
, pp. 232-236
-
-
Van Weemen, B.K.1
Schuurs, A.H.W.M.2
-
112
-
-
84891696767
-
When tissue antigens and antibodies get along: Revisiting the technical aspects of immunohistochemistry-The red, brown, and blue technique
-
Ramos-Vara, J.A.; Miller, M.A. When tissue antigens and antibodies get along: Revisiting the technical aspects of immunohistochemistry-The red, brown, and blue technique. Vet. Pathol. Online 2014, 51, 42-87.
-
(2014)
Vet. Pathol. Online
, vol.51
, pp. 42-87
-
-
Ramos-Vara, J.A.1
Miller, M.A.2
-
113
-
-
0026575221
-
Selection of single-stranded DNA molecules that bind and inhibit human thrombin
-
Bock, L.C.; Griffin, L.C.; Latham, J.A.; Vermaas, E.H.; Toole, J.J. Selection of single-stranded DNA molecules that bind and inhibit human thrombin. Nature 1992, 355, 564-566.
-
(1992)
Nature
, vol.355
, pp. 564-566
-
-
Bock, L.C.1
Griffin, L.C.2
Latham, J.A.3
Vermaas, E.H.4
Toole, J.J.5
-
114
-
-
21844443592
-
Structural characterization of an anti-gp120 rna aptamer that neutralizes r5 strains of HIV-1
-
Dey, A.K.; Griffiths, C.; Lea, S.M.; James, W. Structural characterization of an anti-gp120 rna aptamer that neutralizes r5 strains of HIV-1. RNA 2005, 11, 873-884.
-
(2005)
RNA
, vol.11
, pp. 873-884
-
-
Dey, A.K.1
Griffiths, C.2
Lea, S.M.3
James, W.4
-
115
-
-
54849404705
-
Superparamagnetic iron oxide nanoparticle-aptamer bioconjugates for combined prostate cancer imaging and therapy
-
Wang, A.Z.; Bagalkot, V.; Vasilliou, C.C.; Gu, F.; Alexis, F.; Zhang, L.; Shaikh, M.; Yuet, K.; Cima, M.J.; Langer, R.; et al. Superparamagnetic iron oxide nanoparticle-aptamer bioconjugates for combined prostate cancer imaging and therapy. ChemMedChem 2008, 3, 1311-1315.
-
(2008)
ChemMedChem
, vol.3
, pp. 1311-1315
-
-
Wang, A.Z.1
Bagalkot, V.2
Vasilliou, C.C.3
Gu, F.4
Alexis, F.5
Zhang, L.6
Shaikh, M.7
Yuet, K.8
Cima, M.J.9
Langer, R.10
-
116
-
-
77049115176
-
Fluorescent quantum dot-labeled aptamer bioprobes specifically targeting mouse liver cancer cells
-
Zhang, J.; Jia, X.; Lv, X.-J.; Deng, Y.-L.; Xie, H.-Y. Fluorescent quantum dot-labeled aptamer bioprobes specifically targeting mouse liver cancer cells. Talanta 2010, 81, 505-509.
-
(2010)
Talanta
, vol.81
, pp. 505-509
-
-
Zhang, J.1
Jia, X.2
Lv, X.-J.3
Deng, Y.-L.4
Xie, H.-Y.5
-
117
-
-
84877119720
-
Target binding improves relaxivity in aptamer-gadolinium conjugates
-
Bernard, E.; Beking, M.; Rajamanickam, K.; Tsai, E.; DeRosa, M. Target binding improves relaxivity in aptamer-gadolinium conjugates. J. Biol. Inorg. Chem. 2012, 17, 1159-1175.
-
(2012)
J. Biol. Inorg. Chem.
, vol.17
, pp. 1159-1175
-
-
Bernard, E.1
Beking, M.2
Rajamanickam, K.3
Tsai, E.4
DeRosa, M.5
-
118
-
-
84926328039
-
A covalent approach for site-specific RNA labeling in mammalian cells
-
Li, F.; Dong, J.; Hu, X.; Gong, W.; Li, J.; Shen, J.; Tian, H.; Wang, J. A covalent approach for site-specific RNA labeling in mammalian cells. Angew. Chem. Int. Ed. 2015, 54, 4597-4602.
-
(2015)
Angew. Chem. Int. Ed.
, vol.54
, pp. 4597-4602
-
-
Li, F.1
Dong, J.2
Hu, X.3
Gong, W.4
Li, J.5
Shen, J.6
Tian, H.7
Wang, J.8
-
119
-
-
0031279943
-
In vivo imaging of inflammation using an aptamer inhibitor of human neutrophil elastase
-
Charlton, J.; Sennello, J.; Smith, D. In vivo imaging of inflammation using an aptamer inhibitor of human neutrophil elastase. Chem. Biol. 1997, 4, 809-816.
-
(1997)
Chem. Biol.
, vol.4
, pp. 809-816
-
-
Charlton, J.1
Sennello, J.2
Smith, D.3
-
120
-
-
27744539110
-
Targeted inhibition of αvβ3 integrin with an rna aptamer impairs endothelial cell growth and survival
-
Mi, J.; Zhang, X.; Giangrande, P.H.; McNamara Ii, J.O.; Nimjee, S.M.; Sarraf-Yazdi, S.; Sullenger, B.A.; Clary, B.M. Targeted inhibition of αvβ3 integrin with an rna aptamer impairs endothelial cell growth and survival. Biochem. Biophys. Res. Commun. 2005, 338, 956-963.
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.338
, pp. 956-963
-
-
Mi, J.1
Zhang, X.2
Giangrande, P.H.3
McNamara Ii, J.O.4
Nimjee, S.M.5
Sarraf-Yazdi, S.6
Sullenger, B.A.7
Clary, B.M.8
-
121
-
-
33646582037
-
Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo
-
Farokhzad, O.C.; Cheng, J.; Teply, B.A.; Sherifi, I.; Jon, S.; Kantoff, P.W.; Richie, J.P.; Langer, R. Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo. Proc. Natl. Acad. Sci. USA 2006, 103, 6315-6320.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 6315-6320
-
-
Farokhzad, O.C.1
Cheng, J.2
Teply, B.A.3
Sherifi, I.4
Jon, S.5
Kantoff, P.W.6
Richie, J.P.7
Langer, R.8
-
122
-
-
84871032411
-
Aptamer-functionalized, ultra-small, monodisperse silica nanoconjugates for targeted dual-modal imaging of lymph nodes with metastatic tumors
-
Tang, L.; Yang, X.; Dobrucki, L.W.; Chaudhury, I.; Yin, Q.; Yao, C.; Lezmi, S.; Helferich, W.G.; Fan, T.M.; Cheng, J. Aptamer-functionalized, ultra-small, monodisperse silica nanoconjugates for targeted dual-modal imaging of lymph nodes with metastatic tumors. Angew. Chem. Int. Ed. 2012, 51, 12721-12726.
-
(2012)
Angew. Chem. Int. Ed.
, vol.51
, pp. 12721-12726
-
-
Tang, L.1
Yang, X.2
Dobrucki, L.W.3
Chaudhury, I.4
Yin, Q.5
Yao, C.6
Lezmi, S.7
Helferich, W.G.8
Fan, T.M.9
Cheng, J.10
-
123
-
-
84888640357
-
Aptamer-conjugated magnetic nanoparticles enable efficient targeted detection of integrin αvβ3 via magnetic resonance imaging
-
Lim, E.-K.; Kim, B.; Choi, Y.; Ro, Y.; Cho, E.-J.; Lee, J.H.; Ryu, S.-H.; Suh, J.-S.; Haam, S.; Huh, Y.-M. Aptamer-conjugated magnetic nanoparticles enable efficient targeted detection of integrin αvβ3 via magnetic resonance imaging. J. Biomed. Mater. Res. Part A 2014, 102, 49-59.
-
(2014)
J. Biomed. Mater. Res. Part A
, vol.102
, pp. 49-59
-
-
Lim, E.-K.1
Kim, B.2
Choi, Y.3
Ro, Y.4
Cho, E.-J.5
Lee, J.H.6
Ryu, S.-H.7
Suh, J.-S.8
Haam, S.9
Huh, Y.-M.10
-
124
-
-
79952775709
-
Activatable aptamer probe for contrast-enhanced in vivo cancer imaging based on cell membrane protein-triggered conformation alteration
-
Shi, H.; He, X.; Wang, K.; Wu, X.; Ye, X.; Guo, Q.; Tan, W.; Qing, Z.; Yang, X.; Zhou, B. Activatable aptamer probe for contrast-enhanced in vivo cancer imaging based on cell membrane protein-triggered conformation alteration. Proc. Natl. Acad. Sci. USA 2011, 108, 3900-3905.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 3900-3905
-
-
Shi, H.1
He, X.2
Wang, K.3
Wu, X.4
Ye, X.5
Guo, Q.6
Tan, W.7
Qing, Z.8
Yang, X.9
Zhou, B.10
-
125
-
-
84879233534
-
2+ quantum dots for tumor-targeted fluorescence imaging in vitro and in vivo
-
2+ quantum dots for tumor-targeted fluorescence imaging in vitro and in vivo. Anal. Chem. 2013, 85, 5843-5849.
-
(2013)
Anal. Chem.
, vol.85
, pp. 5843-5849
-
-
Zhang, C.1
Ji, X.2
Zhang, Y.3
Zhou, G.4
Ke, X.5
Wang, H.6
Tinnefeld, P.7
He, Z.8
-
126
-
-
84901684196
-
Selective uptake and imaging of aptamer- and antibody-conjugated hollow nanospheres targeted to epidermal growth factor receptors overexpressed in head and neck cancer
-
Melancon, M.P.; Zhou, M.; Zhang, R.; Xiong, C.; Allen, P.; Wen, X.; Huang, Q.; Wallace, M.; Myers, J.N.; Stafford, R.J.; et al. Selective uptake and imaging of aptamer- and antibody-conjugated hollow nanospheres targeted to epidermal growth factor receptors overexpressed in head and neck cancer. ACS Nano 2014, 8, 4530-4538.
-
(2014)
ACS Nano
, vol.8
, pp. 4530-4538
-
-
Melancon, M.P.1
Zhou, M.2
Zhang, R.3
Xiong, C.4
Allen, P.5
Wen, X.6
Huang, Q.7
Wallace, M.8
Myers, J.N.9
Stafford, R.J.10
-
127
-
-
84912074059
-
A versatile activatable fluorescence probing platform for cancer cells in vitro and in vivo based on self-assembled aptamer/carbon nanotube ensembles
-
Yan, L.A.; Shi, H.; He, X.; Wang, K.; Tang, J.; Chen, M.; Ye, X.; Xu, F.; Lei, Y. A versatile activatable fluorescence probing platform for cancer cells in vitro and in vivo based on self-assembled aptamer/carbon nanotube ensembles. Anal. Chem. 2014, 86, 9271-9277.
-
(2014)
Anal. Chem.
, vol.86
, pp. 9271-9277
-
-
Yan, L.A.1
Shi, H.2
He, X.3
Wang, K.4
Tang, J.5
Chen, M.6
Ye, X.7
Xu, F.8
Lei, Y.9
-
128
-
-
84887270439
-
Aptamer-modified magnetic nanoprobe for molecular mr imaging of VEGFR2 on angiogenic vasculature
-
Kim, B.; Yang, J.; Hwang, M.; Choi, J.; Kim, H.-O.; Jang, E.; Lee, J.; Ryu, S.-H.; Suh, J.-S.; Huh, Y.-M.; et al. Aptamer-modified magnetic nanoprobe for molecular mr imaging of VEGFR2 on angiogenic vasculature. Nanoscale Res. Lett. 2013, 8, 399.
-
(2013)
Nanoscale Res. Lett.
, vol.8
, pp. 399
-
-
Kim, B.1
Yang, J.2
Hwang, M.3
Choi, J.4
Kim, H.-O.5
Jang, E.6
Lee, J.7
Ryu, S.-H.8
Suh, J.-S.9
Huh, Y.-M.10
-
129
-
-
7444223607
-
Nanoparticle-aptamer bioconjugates: A new approach for targeting prostate cancer cells
-
Farokhzad, O.C.; Jon, S.; Khademhosseini, A.; Tran, T.-N.T.; LaVan, D.A.; Langer, R. Nanoparticle-aptamer bioconjugates: A new approach for targeting prostate cancer cells. Cancer Res. 2004, 64, 7668-7672.
-
(2004)
Cancer Res.
, vol.64
, pp. 7668-7672
-
-
Farokhzad, O.C.1
Jon, S.2
Khademhosseini, A.3
Tran, T.-N.T.4
LaVan, D.A.5
Langer, R.6
-
130
-
-
80051817418
-
Aptamer-functionalized peg-plga nanoparticles for enhanced anti-glioma drug delivery
-
Guo, J.; Gao, X.; Su, L.; Xia, H.; Gu, G.; Pang, Z.; Jiang, X.; Yao, L.; Chen, J.; Chen, H. Aptamer-functionalized peg-plga nanoparticles for enhanced anti-glioma drug delivery. Biomaterials 2011, 32, 8010-8020.
-
(2011)
Biomaterials
, vol.32
, pp. 8010-8020
-
-
Guo, J.1
Gao, X.2
Su, L.3
Xia, H.4
Gu, G.5
Pang, Z.6
Jiang, X.7
Yao, L.8
Chen, J.9
Chen, H.10
-
131
-
-
66449095059
-
Current advances in research and clinical applications of plga-based nanotechnology
-
Lü, J.-M.; Wang, X.; Marin-Muller, C.; Wang, H.; Lin, P.H.; Yao, Q.; Chen, C. Current advances in research and clinical applications of plga-based nanotechnology. Expert Rev. Mol. Diagn. 2009, 9, 325-341.
-
(2009)
Expert Rev. Mol. Diagn.
, vol.9
, pp. 325-341
-
-
Lü, J.-M.1
Wang, X.2
Marin-Muller, C.3
Wang, H.4
Lin, P.H.5
Yao, Q.6
Chen, C.7
-
132
-
-
77956036859
-
Poly(ethylene glycol) in drug delivery: Pros and cons as well as potential alternatives
-
Knop, K.; Hoogenboom, R.; Fischer, D.; Schubert, U.S. Poly(ethylene glycol) in drug delivery: Pros and cons as well as potential alternatives. Angew. Chem. Int. Ed. 2010, 49, 6288-6308.
-
(2010)
Angew. Chem. Int. Ed.
, vol.49
, pp. 6288-6308
-
-
Knop, K.1
Hoogenboom, R.2
Fischer, D.3
Schubert, U.S.4
-
133
-
-
84862673737
-
Plga-based nanoparticles: An overview of biomedical applications
-
Danhier, F.; Ansorena, E.; Silva, J.M.; Coco, R.; Le Breton, A.; Préat, V. Plga-based nanoparticles: An overview of biomedical applications. J. Control. Release 2012, 161, 505-522.
-
(2012)
J. Control. Release
, vol.161
, pp. 505-522
-
-
Danhier, F.1
Ansorena, E.2
Silva, J.M.3
Coco, R.4
Le Breton, A.5
Préat, V.6
-
134
-
-
0034734990
-
Virosomes: Evolution of the liposome as a targeted drug delivery system
-
Kaneda, Y. Virosomes: Evolution of the liposome as a targeted drug delivery system. Adv. Drug Deliv. Rev. 2000, 43, 197-205.
-
(2000)
Adv. Drug Deliv. Rev.
, vol.43
, pp. 197-205
-
-
Kaneda, Y.1
-
135
-
-
14144250911
-
Recent advances with liposomes as pharmaceutical carriers
-
Torchilin, V.P. Recent advances with liposomes as pharmaceutical carriers. Nat. Rev. Drug Discov. 2005, 4, 145-160.
-
(2005)
Nat. Rev. Drug Discov.
, vol.4
, pp. 145-160
-
-
Torchilin, V.P.1
-
136
-
-
33748581303
-
Gmp production of liposomes-A new industrial approach
-
Wagner, A.; Platzgummer, M.; Kreismayr, G.; Quendler, H.; Stiegler, G.; Ferko, B.; Vecera, G.; Vorauer-Uhl, K.; Katinger, H. Gmp production of liposomes-A new industrial approach. J. Liposome Res. 2006, 16, 311-319.
-
(2006)
J. Liposome Res.
, vol.16
, pp. 311-319
-
-
Wagner, A.1
Platzgummer, M.2
Kreismayr, G.3
Quendler, H.4
Stiegler, G.5
Ferko, B.6
Vecera, G.7
Vorauer-Uhl, K.8
Katinger, H.9
-
137
-
-
84884397713
-
Selective delivery of an anticancer drug with aptamer-functionalized liposomes to breast cancer cells in vitro and in vivo
-
Xing, H.; Tang, L.; Yang, X.; Hwang, K.; Wang, W.; Yin, Q.; Wong, N.Y.; Dobrucki, L.W.; Yasui, N.; Katzenellenbogen, J.A.; et al. Selective delivery of an anticancer drug with aptamer-functionalized liposomes to breast cancer cells in vitro and in vivo. J. Mater. Chem. B 2013, 1, 5288-5297.
-
(2013)
J. Mater. Chem. B
, vol.1
, pp. 5288-5297
-
-
Xing, H.1
Tang, L.2
Yang, X.3
Hwang, K.4
Wang, W.5
Yin, Q.6
Wong, N.Y.7
Dobrucki, L.W.8
Yasui, N.9
Katzenellenbogen, J.A.10
-
138
-
-
70349898026
-
Reversible cell-specific drug delivery with aptamer-functionalized liposomes
-
Cao, Z.; Tong, R.; Mishra, A.; Xu, W.; Wong, G.C.L.; Cheng, J.; Lu, Y. Reversible cell-specific drug delivery with aptamer-functionalized liposomes. Angew. Chem. Int. Ed. 2009, 48, 6494-6498.
-
(2009)
Angew. Chem. Int. Ed.
, vol.48
, pp. 6494-6498
-
-
Cao, Z.1
Tong, R.2
Mishra, A.3
Xu, W.4
Wong, G.C.L.5
Cheng, J.6
Lu, Y.7
-
139
-
-
84888321871
-
Nucleolin targeting as1411 modified protein nanoparticle for antitumor drugs delivery
-
Wu, J.; Song, C.; Jiang, C.; Shen, X.; Qiao, Q.; Hu, Y. Nucleolin targeting as1411 modified protein nanoparticle for antitumor drugs delivery. Mol. Pharm. 2013, 10, 3555-3563.
-
(2013)
Mol. Pharm.
, vol.10
, pp. 3555-3563
-
-
Wu, J.1
Song, C.2
Jiang, C.3
Shen, X.4
Qiao, Q.5
Hu, Y.6
-
140
-
-
84925516251
-
Aptamer-functionalized lipid nanoparticles targeting osteoblasts as a novel RNA interference-based bone anabolic strategy
-
Liang, C.; Guo, B.; Wu, H.; Shao, N.; Li, D.; Liu, J.; Dang, L.; Wang, C.; Li, H.; Li, S.; et al. Aptamer-functionalized lipid nanoparticles targeting osteoblasts as a novel RNA interference-based bone anabolic strategy. Nat. Med. 2015, 21, 288-294.
-
(2015)
Nat. Med.
, vol.21
, pp. 288-294
-
-
Liang, C.1
Guo, B.2
Wu, H.3
Shao, N.4
Li, D.5
Liu, J.6
Dang, L.7
Wang, C.8
Li, H.9
Li, S.10
-
141
-
-
0021586266
-
A new class of polymers: Starburst-dendritic macromolecules
-
Tomalia, D.A.; Baker, H.; Dewald, J.; Hall, M.; Kallos, G.; Martin, S.; Roeck, J.; Ryder, J.; Smith, P. A new class of polymers: Starburst-dendritic macromolecules. Polym. J. 1985, 17, 117-132.
-
(1985)
Polym. J.
, vol.17
, pp. 117-132
-
-
Tomalia, D.A.1
Baker, H.2
Dewald, J.3
Hall, M.4
Kallos, G.5
Martin, S.6
Roeck, J.7
Ryder, J.8
Smith, P.9
-
142
-
-
18444392735
-
Birth of a new macromolecular architecture: Dendrimers as quantized building blocks for nanoscale synthetic polymer chemistry
-
Tomalia, D.A. Birth of a new macromolecular architecture: Dendrimers as quantized building blocks for nanoscale synthetic polymer chemistry. Prog. Polym. Sci. 2005, 30, 294-324.
-
(2005)
Prog. Polym. Sci.
, vol.30
, pp. 294-324
-
-
Tomalia, D.A.1
-
143
-
-
84935909642
-
Surface-engineered dendrimers in gene delivery
-
Yang, J.; Zhang, Q.; Chang, H.; Cheng, Y. Surface-engineered dendrimers in gene delivery. Chem. Rev. 2015, 115, 5274-5300.
-
(2015)
Chem. Rev.
, vol.115
, pp. 5274-5300
-
-
Yang, J.1
Zhang, Q.2
Chang, H.3
Cheng, Y.4
-
144
-
-
28744443398
-
Dendrimers in biomedical applications-Reflections on the field
-
Svenson, S.; Tomalia, D.A. Dendrimers in biomedical applications-Reflections on the field. Adv. Drug Deliv. Rev. 2005, 57, 2106-2129.
-
(2005)
Adv. Drug Deliv. Rev.
, vol.57
, pp. 2106-2129
-
-
Svenson, S.1
Tomalia, D.A.2
-
145
-
-
70449670896
-
A hybrid DNA aptamer-dendrimer nanomaterial for targeted cell labeling
-
Zhou, J.; Soontornworajit, B.; Martin, J.; Sullenger, B.A.; Gilboa, E.; Wang, Y. A hybrid DNA aptamer-dendrimer nanomaterial for targeted cell labeling. Macromol. Biosci. 2009, 9, 831-835.
-
(2009)
Macromol. Biosci.
, vol.9
, pp. 831-835
-
-
Zhou, J.1
Soontornworajit, B.2
Martin, J.3
Sullenger, B.A.4
Gilboa, E.5
Wang, Y.6
-
146
-
-
77955571891
-
A temperature-responsive antibody-like nanostructure
-
Zhou, J.; Soontornworajit, B.; Wang, Y. A temperature-responsive antibody-like nanostructure. Biomacromolecules 2010, 11, 2087-2093.
-
(2010)
Biomacromolecules
, vol.11
, pp. 2087-2093
-
-
Zhou, J.1
Soontornworajit, B.2
Wang, Y.3
-
147
-
-
80054681184
-
Targeted chemoimmunotherapy using drug-loaded aptamer-dendrimer bioconjugates
-
Lee, I.-H.; An, S.; Yu, M.K.; Kwon, H.-K.; Im, S.-H.; Jon, S. Targeted chemoimmunotherapy using drug-loaded aptamer-dendrimer bioconjugates. J. Control. Release 2011, 155, 435-441.
-
(2011)
J. Control. Release
, vol.155
, pp. 435-441
-
-
Lee, I.-H.1
An, S.2
Yu, M.K.3
Kwon, H.-K.4
Im, S.-H.5
Jon, S.6
-
148
-
-
23844514389
-
Phase i/ii combined chemoimmunotherapy with carcinoembryonic antigen-derived HLA-a2-restricted cap-1 peptide and irinotecan, 5-fluorouracil, and leucovorin in patients with primary metastatic colorectal cancer
-
Weihrauch, M.R.; Ansén, S.; Jurkiewicz, E.; Geisen, C.; Xia, Z.; Anderson, K.S.; Gracien, E.; Schmidt, M.; Wittig, B.; Diehl, V.; et al. Phase i/ii combined chemoimmunotherapy with carcinoembryonic antigen-derived HLA-a2-restricted cap-1 peptide and irinotecan, 5-fluorouracil, and leucovorin in patients with primary metastatic colorectal cancer. Clin. Cancer Res. 2005, 11, 5993-6001.
-
(2005)
Clin. Cancer Res.
, vol.11
, pp. 5993-6001
-
-
Weihrauch, M.R.1
Ansén, S.2
Jurkiewicz, E.3
Geisen, C.4
Xia, Z.5
Anderson, K.S.6
Gracien, E.7
Schmidt, M.8
Wittig, B.9
Diehl, V.10
-
149
-
-
49549123625
-
Topical cpg enhances the response of murine malignant melanoma to dacarbazine
-
Najar, H.M.; Dutz, J.P. Topical cpg enhances the response of murine malignant melanoma to dacarbazine. J. Investig. Dermatol. 2008, 128, 2204-2210.
-
(2008)
J. Investig. Dermatol.
, vol.128
, pp. 2204-2210
-
-
Najar, H.M.1
Dutz, J.P.2
-
150
-
-
84878570297
-
Phase i study of tremelimumab (cp-675[thinsp]206) plus pf-3512676 (cpg 7909) in patients with melanoma or advanced solid tumours
-
Millward, M.; Underhill, C.; Lobb, S.; McBurnie, J.; Meech, S.J.; Gomez-Navarro, J.; Marshall, M.A.; Huang, B.; Mather, C.B. Phase i study of tremelimumab (cp-675[thinsp]206) plus pf-3512676 (cpg 7909) in patients with melanoma or advanced solid tumours. Br. J. Cancer 2013, 108, 1998-2004.
-
(2013)
Br. J. Cancer
, vol.108
, pp. 1998-2004
-
-
Millward, M.1
Underhill, C.2
Lobb, S.3
McBurnie, J.4
Meech, S.J.5
Gomez-Navarro, J.6
Marshall, M.A.7
Huang, B.8
Mather, C.B.9
-
151
-
-
84900513441
-
Improved in vitro efficacy of gold nanoconstructs by increased loading of g-quadruplex aptamer
-
Dam, D.H.M.; Lee, R.C.; Odom, T.W. Improved in vitro efficacy of gold nanoconstructs by increased loading of g-quadruplex aptamer. Nano Lett. 2014, 14, 2843-2848.
-
(2014)
Nano Lett.
, vol.14
, pp. 2843-2848
-
-
Dam, D.H.M.1
Lee, R.C.2
Odom, T.W.3
-
152
-
-
84924287815
-
Single-walled carbon nanotubes functionalized with aptamer and piperazine-polyethylenimine derivative for targeted sirna delivery into breast cancer cells
-
Mohammadi, M.; Salmasi, Z.; Hashemi, M.; Mosaffa, F.; Abnous, K.; Ramezani, M. Single-walled carbon nanotubes functionalized with aptamer and piperazine-polyethylenimine derivative for targeted sirna delivery into breast cancer cells. Int. J. Pharm. 2015, 485, 50-60.
-
(2015)
Int. J. Pharm.
, vol.485
, pp. 50-60
-
-
Mohammadi, M.1
Salmasi, Z.2
Hashemi, M.3
Mosaffa, F.4
Abnous, K.5
Ramezani, M.6
-
153
-
-
79551561775
-
Reversible targeting and controlled release delivery of daunorubicin to cancer cells by aptamer-wrapped carbon nanotubes
-
Taghdisi, S.M.; Lavaee, P.; Ramezani, M.; Abnous, K. Reversible targeting and controlled release delivery of daunorubicin to cancer cells by aptamer-wrapped carbon nanotubes. Eur. J. Pharm. Biopharm. 2011, 77, 200-206.
-
(2011)
Eur. J. Pharm. Biopharm.
, vol.77
, pp. 200-206
-
-
Taghdisi, S.M.1
Lavaee, P.2
Ramezani, M.3
Abnous, K.4
-
154
-
-
84924565724
-
Photothermal therapeutic response of cancer cells to aptamer-gold nanoparticle-hybridized graphene oxide under nir illumination
-
Yang, L.; Tseng, Y.-T.; Suo, G.; Chen, L.; Yu, J.; Chiu, W.-J.; Huang, C.-C.; Lin, C.-H. Photothermal therapeutic response of cancer cells to aptamer-gold nanoparticle-hybridized graphene oxide under nir illumination. ACS Appl. Mater. Interfaces 2015, 7, 5097-5106.
-
(2015)
ACS Appl. Mater. Interfaces
, vol.7
, pp. 5097-5106
-
-
Yang, L.1
Tseng, Y.-T.2
Suo, G.3
Chen, L.4
Yu, J.5
Chiu, W.-J.6
Huang, C.-C.7
Lin, C.-H.8
-
155
-
-
80051500899
-
Image-guided prostate cancer therapy using aptamer-functionalized thermally cross-linked superparamagnetic iron oxide nanoparticles
-
Yu, M.K.; Kim, D.; Lee, I.-H.; So, J.-S.; Jeong, Y.Y.; Jon, S. Image-guided prostate cancer therapy using aptamer-functionalized thermally cross-linked superparamagnetic iron oxide nanoparticles. Small 2011, 7, 2241-2249.
-
(2011)
Small
, vol.7
, pp. 2241-2249
-
-
Yu, M.K.1
Kim, D.2
Lee, I.-H.3
So, J.-S.4
Jeong, Y.Y.5
Jon, S.6
-
156
-
-
84882815878
-
Therapeutic nanomedicine based on dual-intelligent functionalized gold nanoparticles for cancer imaging and therapy in vivo
-
Chen, W.-H.; Xu, X.-D.; Jia, H.-Z.; Lei, Q.; Luo, G.-F.; Cheng, S.-X.; Zhuo, R.-X.; Zhang, X.-Z. Therapeutic nanomedicine based on dual-intelligent functionalized gold nanoparticles for cancer imaging and therapy in vivo. Biomaterials 2013, 34, 8798-8807.
-
(2013)
Biomaterials
, vol.34
, pp. 8798-8807
-
-
Chen, W.-H.1
Xu, X.-D.2
Jia, H.-Z.3
Lei, Q.4
Luo, G.-F.5
Cheng, S.-X.6
Zhuo, R.-X.7
Zhang, X.-Z.8
-
157
-
-
11144239923
-
Pegaptanib for neovascular age-related macular degeneration
-
Gragoudas, E.S.; Adamis, A.P.; Cunningham, E.T.; Feinsod, M.; Guyer, D.R. Pegaptanib for neovascular age-related macular degeneration. New Engl. J. Med. 2004, 351, 2805-2816.
-
(2004)
New Engl. J. Med.
, vol.351
, pp. 2805-2816
-
-
Gragoudas, E.S.1
Adamis, A.P.2
Cunningham, E.T.3
Feinsod, M.4
Guyer, D.R.5
-
158
-
-
34547802193
-
Pegaptanib and ranibizumab for neovascular age-related macular degeneration: A systematic review
-
Takeda, A.L.; Colquitt, J.; Clegg, A.J.; Jones, J. Pegaptanib and ranibizumab for neovascular age-related macular degeneration: A systematic review. Br. J. Ophthalmol. 2007, 91, 1177-1182.
-
(2007)
Br. J. Ophthalmol.
, vol.91
, pp. 1177-1182
-
-
Takeda, A.L.1
Colquitt, J.2
Clegg, A.J.3
Jones, J.4
-
159
-
-
41149100730
-
Pharmacotherapy for the treatment of choroidal neovascularization due to age-related macular degeneration
-
Novack, G.D. Pharmacotherapy for the treatment of choroidal neovascularization due to age-related macular degeneration. Annu. Rev. Pharmacol. Toxicol. 2008, 48, 61-78.
-
(2008)
Annu. Rev. Pharmacol. Toxicol.
, vol.48
, pp. 61-78
-
-
Novack, G.D.1
-
160
-
-
84928780864
-
Predicting the uncertain future of aptamer-based diagnostics and therapeutics
-
Bruno, J. Predicting the uncertain future of aptamer-based diagnostics and therapeutics. Molecules 2015, 20, 6866-6887.
-
(2015)
Molecules
, vol.20
, pp. 6866-6887
-
-
Bruno, J.1
-
161
-
-
84870680921
-
Therapeutic RNA aptamers in clinical trials
-
Sundaram, P.; Kurniawan, H.; Byrne, M.E.; Wower, J. Therapeutic RNA aptamers in clinical trials. Eur. J. Pharm. Sci. 2013, 48, 259-271.
-
(2013)
Eur. J. Pharm. Sci.
, vol.48
, pp. 259-271
-
-
Sundaram, P.1
Kurniawan, H.2
Byrne, M.E.3
Wower, J.4
-
162
-
-
84907312881
-
Oligonucleotide aptamers: New tools for targeted cancer therapy
-
Sun, H.; Zhu, X.; Lu, P.Y.; Rosato, R.R.; Tan, W.; Zu, Y. Oligonucleotide aptamers: New tools for targeted cancer therapy. Mol. Ther. Nucleic Acids 2014, 3, e182.
-
(2014)
Mol. Ther. Nucleic Acids
, vol.3
-
-
Sun, H.1
Zhu, X.2
Lu, P.Y.3
Rosato, R.R.4
Tan, W.5
Zu, Y.6
-
163
-
-
34447646310
-
Programmed death-1 ligand 1 interacts specifically with the b7-1 costimulatory molecule to inhibit t cell responses
-
Butte, M.J.; Keir, M.E.; Phamduy, T.B.; Sharpe, A.H.; Freeman, G.J. Programmed death-1 ligand 1 interacts specifically with the b7-1 costimulatory molecule to inhibit t cell responses. Immunity 2007, 27, 111-122.
-
(2007)
Immunity
, vol.27
, pp. 111-122
-
-
Butte, M.J.1
Keir, M.E.2
Phamduy, T.B.3
Sharpe, A.H.4
Freeman, G.J.5
-
164
-
-
42649125225
-
Pd-1 and its ligands in tolerance and immunity
-
Keir, M.E.; Butte, M.J.; Freeman, G.J.; Sharpe, A.H. Pd-1 and its ligands in tolerance and immunity. Annu. Rev. Immunol. 2008, 26, 677-704.
-
(2008)
Annu. Rev. Immunol.
, vol.26
, pp. 677-704
-
-
Keir, M.E.1
Butte, M.J.2
Freeman, G.J.3
Sharpe, A.H.4
-
165
-
-
0028484545
-
Ctla-4 can function as a negative regulator of t cell activation
-
Walunas, T.L.; Lenschow, D.J.; Bakker, C.Y.; Linsley, P.S.; Freeman, G.J.; Green, J.M.; Thompson, C.B.; Bluestone, J.A. Ctla-4 can function as a negative regulator of t cell activation. Immunity 1994, 1, 405-413.
-
(1994)
Immunity
, vol.1
, pp. 405-413
-
-
Walunas, T.L.1
Lenschow, D.J.2
Bakker, C.Y.3
Linsley, P.S.4
Freeman, G.J.5
Green, J.M.6
Thompson, C.B.7
Bluestone, J.A.8
-
166
-
-
0029120245
-
Cd28 and ctla-4 have opposing effects on the response of t cells to stimulation
-
Krummel, M.F.; Allison, J.P. Cd28 and ctla-4 have opposing effects on the response of t cells to stimulation. J. Exp. Med. 1995, 182, 459-465.
-
(1995)
J. Exp. Med.
, vol.182
, pp. 459-465
-
-
Krummel, M.F.1
Allison, J.P.2
-
167
-
-
0035757397
-
T-cell regulation by cd28 and ctla-4
-
Alegre, M.-L.; Frauwirth, K.A.; Thompson, C.B. T-cell regulation by cd28 and ctla-4. Nat. Rev. Immunol. 2001, 1, 220-228.
-
(2001)
Nat. Rev. Immunol.
, vol.1
, pp. 220-228
-
-
Alegre, M.-L.1
Frauwirth, K.A.2
Thompson, C.B.3
-
168
-
-
70349234325
-
B7-h1 (pd-l1, cd274) Suppresses Host Immunity in T-cell Lymphoproliferative Disorders
-
Wilcox, R.A.; Feldman, A.L.; Wada, D.A.; Yang, Z.-Z.; Comfere, N.I.; Dong, H.; Kwon, E.D.; Novak, A.J.; Markovic, S.N.; Pittelkow, M.R.; et al. B7-h1 (pd-l1, cd274) Suppresses Host Immunity in T-cell Lymphoproliferative Disorders. Blood 2009, 114, 2149-2158.
-
(2009)
Blood
, vol.114
, pp. 2149-2158
-
-
Wilcox, R.A.1
Feldman, A.L.2
Wada, D.A.3
Yang, Z.-Z.4
Comfere, N.I.5
Dong, H.6
Kwon, E.D.7
Novak, A.J.8
Markovic, S.N.9
Pittelkow, M.R.10
-
169
-
-
79952816655
-
Mhc class ii transactivator ciita is a recurrent gene fusion partner in lymphoid cancers
-
Steidl, C.; Shah, S.P.; Woolcock, B.W.; Rui, L.; Kawahara, M.; Farinha, P.; Johnson, N.A.; Zhao, Y.; Telenius, A.; Neriah, S.B.; et al. Mhc class ii transactivator ciita is a recurrent gene fusion partner in lymphoid cancers. Nature 2011, 471, 377-381.
-
(2011)
Nature
, vol.471
, pp. 377-381
-
-
Steidl, C.1
Shah, S.P.2
Woolcock, B.W.3
Rui, L.4
Kawahara, M.5
Farinha, P.6
Johnson, N.A.7
Zhao, Y.8
Telenius, A.9
Neriah, S.B.10
-
170
-
-
84858206832
-
Constitutive ap-1 activity and ebv infection induce pd-l1 in hodgkin lymphomas and posttransplant lymphoproliferative disorders: Implications for targeted therapy
-
Green, M.R.; Rodig, S.; Juszczynski, P.; Ouyang, J.; Sinha, P.; O'Donnell, E.; Neuberg, D.; Shipp, M.A. Constitutive ap-1 activity and ebv infection induce pd-l1 in hodgkin lymphomas and posttransplant lymphoproliferative disorders: Implications for targeted therapy. Clin. Cancer Res. 2012, 18, 1611-1618.
-
(2012)
Clin. Cancer Res.
, vol.18
, pp. 1611-1618
-
-
Green, M.R.1
Rodig, S.2
Juszczynski, P.3
Ouyang, J.4
Sinha, P.5
O'Donnell, E.6
Neuberg, D.7
Shipp, M.A.8
-
171
-
-
36849035139
-
Targeting cytotoxic t-lymphocyte antigen-4 (ctla-4)
-
O'Day, S.J.; Hamid, O.; Urba, W.J. Targeting cytotoxic t-lymphocyte antigen-4 (ctla-4). Cancer 2007, 110, 2614-2627.
-
(2007)
Cancer
, vol.110
, pp. 2614-2627
-
-
O'Day, S.J.1
Hamid, O.2
Urba, W.J.3
-
172
-
-
70249083099
-
What is the role of cytotoxic t lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma?
-
Robert, C.; Ghiringhelli, F. What is the role of cytotoxic t lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma? Oncologist 2009, 14, 848-861.
-
(2009)
Oncologist
, vol.14
, pp. 848-861
-
-
Robert, C.1
Ghiringhelli, F.2
-
173
-
-
84879759020
-
Safety and tumor responses with lambrolizumab (anti-pd-1) in melanoma
-
Hamid, O.; Robert, C.; Daud, A.; Hodi, F.S.; Hwu, W.-J.; Kefford, R.; Wolchok, J.D.; Hersey, P.; Joseph, R.W.; Weber, J.S.; et al. Safety and tumor responses with lambrolizumab (anti-pd-1) in melanoma. New Engl. J. Med. 2013, 369, 134-144.
-
(2013)
New Engl. J. Med.
, vol.369
, pp. 134-144
-
-
Hamid, O.1
Robert, C.2
Daud, A.3
Hodi, F.S.4
Hwu, W.-J.5
Kefford, R.6
Wolchok, J.D.7
Hersey, P.8
Joseph, R.W.9
Weber, J.S.10
-
174
-
-
84924761598
-
Nivolumab in melanoma: Latest evidence and clinical potential
-
Johnson, D.B.; Peng, C.; Sosman, J.A. Nivolumab in melanoma: Latest evidence and clinical potential. Ther. Adv. Med. Oncol. 2015, 7, 97-106.
-
(2015)
Ther. Adv. Med. Oncol.
, vol.7
, pp. 97-106
-
-
Johnson, D.B.1
Peng, C.2
Sosman, J.A.3
-
175
-
-
84929150634
-
Immunologic checkpoints blockade in renal cell, prostate, and urothelial malignancies
-
Bracarda, S.; Altavilla, A.; Hamzaj, A.; Sisani, M.; Marrocolo, F.; del Buono, S.; Danielli, R. Immunologic checkpoints blockade in renal cell, prostate, and urothelial malignancies. Semin. Oncol. 2015, 42, 495-505.
-
(2015)
Semin. Oncol.
, vol.42
, pp. 495-505
-
-
Bracarda, S.1
Altavilla, A.2
Hamzaj, A.3
Sisani, M.4
Marrocolo, F.5
del Buono, S.6
Danielli, R.7
-
176
-
-
84924809260
-
Nivolumab in nsclc: Latest evidence and clinical potential
-
Sundar, R.; Cho, B.-C.; Brahmer, J.R.; Soo, R.A. Nivolumab in nsclc: Latest evidence and clinical potential. Ther. Adv. Med. Oncol. 2015, 7, 85-96.
-
(2015)
Ther. Adv. Med. Oncol.
, vol.7
, pp. 85-96
-
-
Sundar, R.1
Cho, B.-C.2
Brahmer, J.R.3
Soo, R.A.4
-
177
-
-
62149129236
-
Therapeutic antibodies: Successes, limitations and hopes for the future
-
Chames, P.; Van Regenmortel, M.; Weiss, E.; Baty, D. Therapeutic antibodies: Successes, limitations and hopes for the future. Br. J. Pharmacol. 2009, 157, 220-233.
-
(2009)
Br. J. Pharmacol.
, vol.157
, pp. 220-233
-
-
Chames, P.1
Van Regenmortel, M.2
Weiss, E.3
Baty, D.4
-
178
-
-
77953658260
-
The immunogenicity of humanized and fully human antibodies: Residual immunogenicity resides in the CDR regions
-
Harding, F.A.; Stickler, M.M.; Razo, J.; DuBridge, R.B. The immunogenicity of humanized and fully human antibodies: Residual immunogenicity resides in the CDR regions. mAbs 2010, 2, 256-265.
-
(2010)
mAbs
, vol.2
, pp. 256-265
-
-
Harding, F.A.1
Stickler, M.M.2
Razo, J.3
DuBridge, R.B.4
-
179
-
-
77957361348
-
Development trends for human monoclonal antibody therapeutics
-
Nelson, A.L.; Dhimolea, E.; Reichert, J.M. Development trends for human monoclonal antibody therapeutics. Nat. Rev. Drug Discov. 2010, 9, 767-774.
-
(2010)
Nat. Rev. Drug Discov.
, vol.9
, pp. 767-774
-
-
Nelson, A.L.1
Dhimolea, E.2
Reichert, J.M.3
-
180
-
-
84933177886
-
The development of potential antibody-based therapies for myeloma
-
Sherbenou, D.W.; Behrens, C.R.; Su, Y.; Wolf, J.L.; Martin Iii, T.G.; Liu, B. The development of potential antibody-based therapies for myeloma. Blood Rev. 2015, 29, 81-91.
-
(2015)
Blood Rev.
, vol.29
, pp. 81-91
-
-
Sherbenou, D.W.1
Behrens, C.R.2
Su, Y.3
Wolf, J.L.4
Martin Iii, T.G.5
Liu, B.6
-
181
-
-
84925759142
-
Discovery of functional antibodies targeting ion channels
-
Wilkinson, T.C.I.; Gardener, M.J.; Williams, W.A. Discovery of functional antibodies targeting ion channels. J. Biomol. Screen. 2015, 20, 454-467.
-
(2015)
J. Biomol. Screen.
, vol.20
, pp. 454-467
-
-
Wilkinson, T.C.I.1
Gardener, M.J.2
Williams, W.A.3
-
182
-
-
0242610799
-
Multivalent rna aptamers that inhibit ctla-4 and enhance tumor immunity
-
Santulli-Marotto, S.; Nair, S.K.; Rusconi, C.; Sullenger, B.; Gilboa, E. Multivalent rna aptamers that inhibit ctla-4 and enhance tumor immunity. Cancer Res. 2003, 63, 7483-7489.
-
(2003)
Cancer Res.
, vol.63
, pp. 7483-7489
-
-
Santulli-Marotto, S.1
Nair, S.K.2
Rusconi, C.3
Sullenger, B.4
Gilboa, E.5
-
183
-
-
84940211893
-
Targeting the pd-1/pd-l1 immune evasion axis with DNA aptamers as a novel therapeutic strategy for the treatment of disseminated cancers
-
Prodeus, A.; Abdul-Wahid, A.; Fischer, N.W.; Huang, E.H.B.; Cydzik, M.; Gariepy, J. Targeting the pd-1/pd-l1 immune evasion axis with DNA aptamers as a novel therapeutic strategy for the treatment of disseminated cancers. Mol. Ther. Nucleic Acids 2015, 4, e237.
-
(2015)
Mol. Ther. Nucleic Acids
, vol.4
-
-
Prodeus, A.1
Abdul-Wahid, A.2
Fischer, N.W.3
Huang, E.H.B.4
Cydzik, M.5
Gariepy, J.6
-
184
-
-
0032374052
-
Role of 4-1bb in immune responses
-
Vinay, D.S.; Kwon, B.S. Role of 4-1bb in immune responses. Semin. Immunol. 1998, 10, 481-489.
-
(1998)
Semin. Immunol.
, vol.10
, pp. 481-489
-
-
Vinay, D.S.1
Kwon, B.S.2
-
185
-
-
84940197776
-
Modulation of the immune response through 4-1bb
-
Habib, N., Ed.; Springer US: New York, NY, USA
-
Sica, G.; Chen, L. Modulation of the immune response through 4-1bb. In Cancer Gene Therapy, Habib, N., Ed.; Springer US: New York, NY, USA, 2002; Volume 465, pp. 355-362.
-
(2002)
Cancer Gene Therapy
, vol.465
, pp. 355-362
-
-
Sica, G.1
Chen, L.2
-
186
-
-
0141609073
-
Co-stimulatory members of the tnfr family: Keys to effective t-cell immunity?
-
Croft, M. Co-stimulatory members of the tnfr family: Keys to effective t-cell immunity? Nat. Rev. Immunol. 2003, 3, 609-620.
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 609-620
-
-
Croft, M.1
-
187
-
-
17644389199
-
TNF/TNFR family members in costimulation of t cell responses
-
Watts, T.H. TNF/TNFR family members in costimulation of t cell responses. Annu. Rev. Immunol. 2005, 23, 23-68.
-
(2005)
Annu. Rev. Immunol.
, vol.23
, pp. 23-68
-
-
Watts, T.H.1
-
188
-
-
38149096315
-
Multivalent 4-1bb binding aptamers costimulate cd8(+) t cells and inhibit tumor growth in mice
-
McNamara, J.O.; Kolonias, D.; Pastor, F.; Mittler, R.S.; Chen, L.; Giangrande, P.H.; Sullenger, B.; Gilboa, E. Multivalent 4-1bb binding aptamers costimulate cd8(+) t cells and inhibit tumor growth in mice. J. Clin. Investig. 2008, 118, 376-386.
-
(2008)
J. Clin. Investig.
, vol.118
, pp. 376-386
-
-
McNamara, J.O.1
Kolonias, D.2
Pastor, F.3
Mittler, R.S.4
Chen, L.5
Giangrande, P.H.6
Sullenger, B.7
Gilboa, E.8
-
189
-
-
34250719346
-
Thrombin as procoagulant and anticoagulant
-
Di Cera, E. Thrombin as procoagulant and anticoagulant. J. Thromb. Haemost. 2007, 5, 196-202.
-
(2007)
J. Thromb. Haemost.
, vol.5
, pp. 196-202
-
-
Di Cera, E.1
-
190
-
-
0032697618
-
Biochemistry and physiology of blood coagulation
-
Mann, K.G. Biochemistry and physiology of blood coagulation. Thromb. Haemost. 1999, 82, 165-174.
-
(1999)
Thromb. Haemost.
, vol.82
, pp. 165-174
-
-
Mann, K.G.1
-
192
-
-
79551638273
-
Novel oral factor Xa and thrombin inhibitors in the management of thromboembolism
-
Eriksson, B.I.; Quinlan, D.J.; Eikelboom, J.W. Novel oral factor Xa and thrombin inhibitors in the management of thromboembolism. Annu. Rev. Med. 2011, 62, 41-57.
-
(2011)
Annu. Rev. Med.
, vol.62
, pp. 41-57
-
-
Eriksson, B.I.1
Quinlan, D.J.2
Eikelboom, J.W.3
-
193
-
-
84920811343
-
New approaches to inhibiting platelets and coagulation
-
Depta, J.P.; Bhatt, D.L. New approaches to inhibiting platelets and coagulation. Annu. Rev. Pharmacol. Toxicol. 2015, 55, 373-397.
-
(2015)
Annu. Rev. Pharmacol. Toxicol.
, vol.55
, pp. 373-397
-
-
Depta, J.P.1
Bhatt, D.L.2
-
194
-
-
0028912561
-
The clot thickens: Clues provided by thrombin structure
-
Stubbs, M.T.; Bode, W. The clot thickens: Clues provided by thrombin structure. Trends Biochem. Sci. 1995, 20, 23-28.
-
(1995)
Trends Biochem. Sci.
, vol.20
, pp. 23-28
-
-
Stubbs, M.T.1
Bode, W.2
-
195
-
-
33646470969
-
An overview of the structure and function of thrombin
-
Davie, E.W.; Kulman, J.D. An overview of the structure and function of thrombin. Semin. Thromb. Hemost. 2006, 32, 003-015.
-
(2006)
Semin. Thromb. Hemost.
, vol.32
, pp. 003-015
-
-
Davie, E.W.1
Kulman, J.D.2
-
196
-
-
0027467617
-
Thrombin-binding DNA aptamer forms a unimolecular quadruplex structure in solution
-
Macaya, R.F.; Schultze, P.; Smith, F.W.; Roe, J.A.; Feigon, J. Thrombin-binding DNA aptamer forms a unimolecular quadruplex structure in solution. Proc. Natl. Acad. Sci. 1993, 90, 3745-3749.
-
(1993)
Proc. Natl. Acad. Sci.
, vol.90
, pp. 3745-3749
-
-
Macaya, R.F.1
Schultze, P.2
Smith, F.W.3
Roe, J.A.4
Feigon, J.5
-
197
-
-
0027380687
-
The tertiary structure of a DNA aptamer which binds to and inhibits thrombin determines activity
-
Wang, K.Y.; Krawczyk, S.H.; Bischofberger, N.; Swaminathan, S.; Bolton, P.H. The tertiary structure of a DNA aptamer which binds to and inhibits thrombin determines activity. Biochemistry 1993, 32, 11285-11292.
-
(1993)
Biochemistry
, vol.32
, pp. 11285-11292
-
-
Wang, K.Y.1
Krawczyk, S.H.2
Bischofberger, N.3
Swaminathan, S.4
Bolton, P.H.5
-
198
-
-
0027537022
-
A DNA aptamer which binds to and inhibits thrombin exhibits a new structural motif for DNA
-
Wang, K.Y.; McCurdy, S.; Shea, R.G.; Swaminathan, S.; Bolton, P.H. A DNA aptamer which binds to and inhibits thrombin exhibits a new structural motif for DNA. Biochemistry 1993, 32, 1899-1904.
-
(1993)
Biochemistry
, vol.32
, pp. 1899-1904
-
-
Wang, K.Y.1
McCurdy, S.2
Shea, R.G.3
Swaminathan, S.4
Bolton, P.H.5
-
199
-
-
84870535712
-
High-resolution structures of two complexes between thrombin and thrombin-binding aptamer shed light on the role of cations in the aptamer inhibitory activity
-
Russo Krauss, I.; Merlino, A.; Randazzo, A.; Novellino, E.; Mazzarella, L.; Sica, F. High-resolution structures of two complexes between thrombin and thrombin-binding aptamer shed light on the role of cations in the aptamer inhibitory activity. Nucleic Acids Res. 2012, 40, 8119-8128.
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. 8119-8128
-
-
Russo Krauss, I.1
Merlino, A.2
Randazzo, A.3
Novellino, E.4
Mazzarella, L.5
Sica, F.6
-
200
-
-
84930731789
-
2+ environments
-
2+ environments. Acta Biochim. Biophys. Sin. 2014, 46, 837-850.
-
(2014)
Acta Biochim. Biophys. Sin.
, vol.46
, pp. 837-850
-
-
Zhao, X.1
Liu, B.2
Yan, J.3
Yuan, Y.4
An, L.5
Guan, Y.6
-
201
-
-
0028950659
-
Structural and functional characterization of potent antithrombotic oligonucleotides possessing both quadruplex and duplex motifs
-
Macaya, R.F.; Waldron, J.A.; Beutel, B.A.; Gao, H.; Joesten, M.E.; Yang, M.; Patel, R.; Bertelsen, A.H.; Cook, A.F. Structural and functional characterization of potent antithrombotic oligonucleotides possessing both quadruplex and duplex motifs. Biochemistry 1995, 34, 4478-4492.
-
(1995)
Biochemistry
, vol.34
, pp. 4478-4492
-
-
Macaya, R.F.1
Waldron, J.A.2
Beutel, B.A.3
Gao, H.4
Joesten, M.E.5
Yang, M.6
Patel, R.7
Bertelsen, A.H.8
Cook, A.F.9
-
202
-
-
66149120170
-
Combinatorial synthesis of thrombin-binding aptamers containing iso-guanine
-
Nallagatla, S.R.; Heuberger, B.; Haque, A.; Switzer, C. Combinatorial synthesis of thrombin-binding aptamers containing iso-guanine. J. Comb. Chem. 2009, 11, 364-369.
-
(2009)
J. Comb. Chem.
, vol.11
, pp. 364-369
-
-
Nallagatla, S.R.1
Heuberger, B.2
Haque, A.3
Switzer, C.4
-
203
-
-
84919336419
-
5-hydroxymethyl-2′-deoxyuridine residues in the thrombin binding aptamer: Investigating anticoagulant activity by making a tiny chemical modification
-
Virgilio, A.; Petraccone, L.; Scuotto, M.; Vellecco, V.; Bucci, M.; Mayol, L.; Varra, M.; Esposito, V.; Galeone, A. 5-hydroxymethyl-2′-deoxyuridine residues in the thrombin binding aptamer: Investigating anticoagulant activity by making a tiny chemical modification. ChemBioChem 2014, 15, 2427-2434.
-
(2014)
ChemBioChem
, vol.15
, pp. 2427-2434
-
-
Virgilio, A.1
Petraccone, L.2
Scuotto, M.3
Vellecco, V.4
Bucci, M.5
Mayol, L.6
Varra, M.7
Esposito, V.8
Galeone, A.9
-
204
-
-
84888622849
-
Fluorescence enhancement upon g-quadruplex folding: Synthesis, structure, and biophysical characterization of a dansyl/cyclodextrin-tagged thrombin binding aptamer
-
De Tito, S.; Morvan, F.; Meyer, A.; Vasseur, J.-J.; Cummaro, A.; Petraccone, L.; Pagano, B.; Novellino, E.; Randazzo, A.; Giancola, C.; et al. Fluorescence enhancement upon g-quadruplex folding: Synthesis, structure, and biophysical characterization of a dansyl/cyclodextrin-tagged thrombin binding aptamer. Bioconjugate Chem. 2013, 24, 1917-1927.
-
(2013)
Bioconjugate Chem.
, vol.24
, pp. 1917-1927
-
-
De Tito, S.1
Morvan, F.2
Meyer, A.3
Vasseur, J.-J.4
Cummaro, A.5
Petraccone, L.6
Pagano, B.7
Novellino, E.8
Randazzo, A.9
Giancola, C.10
-
205
-
-
79951575374
-
Improved thrombin binding aptamer by incorporation of a single unlocked nucleic acid monomer
-
Pasternak, A.; Hernandez, F.J.; Rasmussen, L.M.; Vester, B.; Wengel, J. Improved thrombin binding aptamer by incorporation of a single unlocked nucleic acid monomer. Nucleic Acids Res. 2011, 39, 1155-1164.
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. 1155-1164
-
-
Pasternak, A.1
Hernandez, F.J.2
Rasmussen, L.M.3
Vester, B.4
Wengel, J.5
-
206
-
-
0027163099
-
In vivo Anticoagulant Properties of a Novel Nucleotide-Based Thrombin Inhibitor and Demonstration of Regional Anticoagulation in Extracorporeal Circuits
-
Griffin, L.; Tidmarsh, G.; Bock, L.; Toole, J.; Leung, L. In vivo Anticoagulant Properties of a Novel Nucleotide-Based Thrombin Inhibitor and Demonstration of Regional Anticoagulation in Extracorporeal Circuits. Blood 1993, 81, 3271-3276.
-
(1993)
Blood
, vol.81
, pp. 3271-3276
-
-
Griffin, L.1
Tidmarsh, G.2
Bock, L.3
Toole, J.4
Leung, L.5
-
207
-
-
0028097736
-
A Novel Nucleotide-Based Thrombin Inhibitor Inhibits Clot-Bound Thrombin and Reduces Arterial Platelet Thrombus Formation
-
Li, W.; Kaplan, A.; Grant, G.; Toole, J.; Leung, L. A Novel Nucleotide-Based Thrombin Inhibitor Inhibits Clot-Bound Thrombin and Reduces Arterial Platelet Thrombus Formation. Blood 1994, 83, 677-682.
-
(1994)
Blood
, vol.83
, pp. 677-682
-
-
Li, W.1
Kaplan, A.2
Grant, G.3
Toole, J.4
Leung, L.5
-
208
-
-
14544295783
-
Aptamers: An emerging class of therapeutics
-
Nimjee, S.M.; Rusconi, C.P.; Sullenger, B.A. Aptamers: An emerging class of therapeutics. Annu. Rev. Med. 2004, 56, 555-583.
-
(2004)
Annu. Rev. Med.
, vol.56
, pp. 555-583
-
-
Nimjee, S.M.1
Rusconi, C.P.2
Sullenger, B.A.3
-
209
-
-
80052228547
-
Nucleic acid aptamers: Clinical applications and promising new horizons
-
Ni, X.; Castanares, M.; Mukherjee, A.; Lupold, S.E. Nucleic acid aptamers: Clinical applications and promising new horizons. Curr. Med. Chem. 2011, 18, 4206-4214.
-
(2011)
Curr. Med. Chem.
, vol.18
, pp. 4206-4214
-
-
Ni, X.1
Castanares, M.2
Mukherjee, A.3
Lupold, S.E.4
-
210
-
-
74149094591
-
Synthetic therapeutic peptides: Science and market
-
Vlieghe, P.; Lisowski, V.; Martinez, J.; Khrestchatisky, M. Synthetic therapeutic peptides: Science and market. Drug Discov. Today 2010, 15, 40-56.
-
(2010)
Drug Discov. Today
, vol.15
, pp. 40-56
-
-
Vlieghe, P.1
Lisowski, V.2
Martinez, J.3
Khrestchatisky, M.4
-
211
-
-
84919414908
-
Measuring drug distribution in the critically ill patient
-
Deitchman, A.N.; Derendorf, H. Measuring drug distribution in the critically ill patient. Adv. Drug Deliv. Rev. 2014, 77, 22-26.
-
(2014)
Adv. Drug Deliv. Rev.
, vol.77
, pp. 22-26
-
-
Deitchman, A.N.1
Derendorf, H.2
-
212
-
-
84897942468
-
Ph-responsive mesoporous silica nanoparticles employed in controlled drug delivery systems for cancer treatment
-
Yang, K.-N.; Zhang, C.-Q.; Wang, W.; Wang, P.C.; Zhou, J.-P.; Liang, X.-J. Ph-responsive mesoporous silica nanoparticles employed in controlled drug delivery systems for cancer treatment. Cancer Biol. Med. 2014, 11, 34-43.
-
(2014)
Cancer Biol. Med.
, vol.11
, pp. 34-43
-
-
Yang, K.-N.1
Zhang, C.-Q.2
Wang, W.3
Wang, P.C.4
Zhou, J.-P.5
Liang, X.-J.6
-
213
-
-
84919935760
-
Polythiolactone-based redox-responsive layers for the reversible release of functional molecules
-
Belbekhouche, S.; Reinicke, S.; Espeel, P.; Du Prez, F.E.; Eloy, P.; Dupont-Gillain, C.; Jonas, A.M.; Demoustier-Champagne, S.; Glinel, K. Polythiolactone-based redox-responsive layers for the reversible release of functional molecules. ACS Appl. Mater. Interfaces 2014, 6, 22457-22466.
-
(2014)
ACS Appl. Mater. Interfaces
, vol.6
, pp. 22457-22466
-
-
Belbekhouche, S.1
Reinicke, S.2
Espeel, P.3
Du Prez, F.E.4
Eloy, P.5
Dupont-Gillain, C.6
Jonas, A.M.7
Demoustier-Champagne, S.8
Glinel, K.9
-
214
-
-
84867536074
-
Design of enzyme-mediated controlled release systems based on silica mesoporous supports capped with ester-glycol groups
-
Agostini, A.; Mondragón, L.; Pascual, L.; Aznar, E.; Coll, C.; Martínez-Máñez, R.; Sancenón, F.; Soto, J.; Marcos, M.D.; Amorós, P.; et al. Design of enzyme-mediated controlled release systems based on silica mesoporous supports capped with ester-glycol groups. Langmuir 2012, 28, 14766-14776.
-
(2012)
Langmuir
, vol.28
, pp. 14766-14776
-
-
Agostini, A.1
Mondragón, L.2
Pascual, L.3
Aznar, E.4
Coll, C.5
Martínez-Máñez, R.6
Sancenón, F.7
Soto, J.8
Marcos, M.D.9
Amorós, P.10
-
215
-
-
84885716472
-
Enhanced anticancer activity of nanopreparation containing an mmp2-sensitive peg-drug conjugate and cell-penetrating moiety
-
Zhu, L.; Wang, T.; Perche, F.; Taigind, A.; Torchilin, V.P. Enhanced anticancer activity of nanopreparation containing an mmp2-sensitive peg-drug conjugate and cell-penetrating moiety. Proc. Natl. Acad. Sci. USA 2013, 110, 17047-17052.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 17047-17052
-
-
Zhu, L.1
Wang, T.2
Perche, F.3
Taigind, A.4
Torchilin, V.P.5
-
216
-
-
84863653278
-
Glucose-sensitivity of boronic acid block copolymers at physiological pH
-
Roy, D.; Sumerlin, B.S. Glucose-sensitivity of boronic acid block copolymers at physiological pH. ACS Macro Lett. 2012, 1, 529-532.
-
(2012)
ACS Macro Lett.
, vol.1
, pp. 529-532
-
-
Roy, D.1
Sumerlin, B.S.2
-
217
-
-
84919948294
-
Dextran-gated, multifunctional mesoporous nanoparticle for glucose-responsive and targeted drug delivery
-
Sinha, A.; Chakraborty, A.; Jana, N.R. Dextran-gated, multifunctional mesoporous nanoparticle for glucose-responsive and targeted drug delivery. ACS Appl. Mater. Interfaces 2014, 6, 22183-22191.
-
(2014)
ACS Appl. Mater. Interfaces
, vol.6
, pp. 22183-22191
-
-
Sinha, A.1
Chakraborty, A.2
Jana, N.R.3
-
218
-
-
64549135491
-
Triply-responsive boronic acidblock copolymers: Solution self-assembly induced by changes in temperature, pH, or sugar concentration
-
Roy, D.; Cambre, J.N.; Sumerlin, B.S. Triply-responsive boronic acidblock copolymers: Solution self-assembly induced by changes in temperature, pH, or sugar concentration. Chem. Commun. 2009, 2106-2108.
-
(2009)
Chem. Commun.
, pp. 2106-2108
-
-
Roy, D.1
Cambre, J.N.2
Sumerlin, B.S.3
-
219
-
-
84892684120
-
Codendrimer from polyamidoamine (pamam) and oligoethylene dendron as a thermosensitive drug carrier
-
Guo, Y.; Zhao, Y.; Zhao, J.; Han, M.; Zhang, A.; Wang, X. Codendrimer from polyamidoamine (pamam) and oligoethylene dendron as a thermosensitive drug carrier. Bioconjugate Chem. 2014, 25, 24-31.
-
(2014)
Bioconjugate Chem.
, vol.25
, pp. 24-31
-
-
Guo, Y.1
Zhao, Y.2
Zhao, J.3
Han, M.4
Zhang, A.5
Wang, X.6
-
220
-
-
84862953020
-
Micelle-to-vesicle morphological transition via light-induced rapid hydrophilic arm detachment from a star polymer
-
Du, J.-Z.; Long, H.-Y.; Yuan, Y.-Y.; Song, M.-M.; Chen, L.; Bi, H.; Wang, J. Micelle-to-vesicle morphological transition via light-induced rapid hydrophilic arm detachment from a star polymer. Chem. Commun. 2012, 48, 1257-1259.
-
(2012)
Chem. Commun.
, vol.48
, pp. 1257-1259
-
-
Du, J.-Z.1
Long, H.-Y.2
Yuan, Y.-Y.3
Song, M.-M.4
Chen, L.5
Bi, H.6
Wang, J.7
-
221
-
-
84864875088
-
Functional mesoporous silica nanoparticles for photothermal-controlled drug delivery in vivo
-
Yan, H.; Teh, C.; Sreejith, S.; Zhu, L.; Kwok, A.; Fang, W.; Ma, X.; Nguyen, K.T.; Korzh, V.; Zhao, Y. Functional mesoporous silica nanoparticles for photothermal-controlled drug delivery in vivo. Angew. Chem. Int. Ed. 2012, 51, 8373-8377.
-
(2012)
Angew. Chem. Int. Ed.
, vol.51
, pp. 8373-8377
-
-
Yan, H.1
Teh, C.2
Sreejith, S.3
Zhu, L.4
Kwok, A.5
Fang, W.6
Ma, X.7
Nguyen, K.T.8
Korzh, V.9
Zhao, Y.10
-
222
-
-
84886292840
-
Stimuli-responsive nanocarriers for drug delivery
-
Mura, S.; Nicolas, J.; Couvreur, P. Stimuli-responsive nanocarriers for drug delivery. Nat. Mater. 2013, 12, 991-1003.
-
(2013)
Nat. Mater.
, vol.12
, pp. 991-1003
-
-
Mura, S.1
Nicolas, J.2
Couvreur, P.3
-
223
-
-
84904280441
-
Polymeric micelles with stimuli-triggering systems for advanced cancer drug targeting
-
Nakayama, M.; Akimoto, J.; Okano, T. Polymeric micelles with stimuli-triggering systems for advanced cancer drug targeting. J. Drug Target. 2014, 22, 584-599.
-
(2014)
J. Drug Target.
, vol.22
, pp. 584-599
-
-
Nakayama, M.1
Akimoto, J.2
Okano, T.3
-
224
-
-
84919779493
-
Stimuli-responsive polymeric nanoparticles for nanomedicine
-
Crucho, C.I.C. Stimuli-responsive polymeric nanoparticles for nanomedicine. ChemMedChem 2015, 10, 24-38.
-
(2015)
ChemMedChem
, vol.10
, pp. 24-38
-
-
Crucho, C.I.C.1
-
225
-
-
84921777636
-
Biodegradable stimuli-responsive polypeptide materials prepared by ring opening polymerization
-
Shen, Y.; Fu, X.; Fu, W.; Li, Z. Biodegradable stimuli-responsive polypeptide materials prepared by ring opening polymerization. Chem. Soc. Rev. 2015, 44, 612-622.
-
(2015)
Chem. Soc. Rev.
, vol.44
, pp. 612-622
-
-
Shen, Y.1
Fu, X.2
Fu, W.3
Li, Z.4
-
226
-
-
84856168201
-
Peptide-based and polypeptide-based hydrogels for drug delivery and tissue engineering
-
Deming, T., Ed.; Springer Berlin Heidelberg: Berlin, Germany
-
Altunbas, A.; Pochan, D. Peptide-based and polypeptide-based hydrogels for drug delivery and tissue engineering. In Peptide-Based Materials; Deming, T., Ed.; Springer Berlin Heidelberg: Berlin, Germany, 2012; Volume 310, pp. 135-167.
-
(2012)
Peptide-Based Materials
, vol.310
, pp. 135-167
-
-
Altunbas, A.1
Pochan, D.2
-
227
-
-
84925210055
-
High performance and reversible ionic polypeptide hydrogel based on charge-driven assembly for biomedical applications
-
Cui, H.; Zhuang, X.; He, C.; Wei, Y.; Chen, X. High performance and reversible ionic polypeptide hydrogel based on charge-driven assembly for biomedical applications. Acta Biomater. 2015, 11, 183-190.
-
(2015)
Acta Biomater.
, vol.11
, pp. 183-190
-
-
Cui, H.1
Zhuang, X.2
He, C.3
Wei, Y.4
Chen, X.5
-
228
-
-
84863230510
-
Hyaluronic acid-based hydrogels: From a natural polysaccharide to complex networks
-
Xu, X.; Jha, A.K.; Harrington, D.A.; Farach-Carson, M.C.; Jia, X. Hyaluronic acid-based hydrogels: From a natural polysaccharide to complex networks. Soft Matter 2012, 8, 3280-3294.
-
(2012)
Soft Matter
, vol.8
, pp. 3280-3294
-
-
Xu, X.1
Jha, A.K.2
Harrington, D.A.3
Farach-Carson, M.C.4
Jia, X.5
-
229
-
-
84890383173
-
Injectable polysaccharide hydrogels reinforced with cellulose nanocrystals: Morphology, rheology, degradation, and cytotoxicity
-
Yang, X.; Bakaic, E.; Hoare, T.; Cranston, E.D. Injectable polysaccharide hydrogels reinforced with cellulose nanocrystals: Morphology, rheology, degradation, and cytotoxicity. Biomacromolecules 2013, 14, 4447-4455.
-
(2013)
Biomacromolecules
, vol.14
, pp. 4447-4455
-
-
Yang, X.1
Bakaic, E.2
Hoare, T.3
Cranston, E.D.4
-
230
-
-
84870948305
-
Fabricating three-dimensional hydrogel oligonucleotide microarrays to detect single nucleotide polymorphisms
-
Liu, X.; Li, T.; Liu, D.; Wang, Z. Fabricating three-dimensional hydrogel oligonucleotide microarrays to detect single nucleotide polymorphisms. Anal. Methods 2013, 5, 285-290.
-
(2013)
Anal. Methods
, vol.5
, pp. 285-290
-
-
Liu, X.1
Li, T.2
Liu, D.3
Wang, Z.4
-
231
-
-
84924942233
-
Microfluidic linear hydrogel array for multiplexed single nucleotide polymorphism (SNP) detection
-
Jung, Y.K.; Kim, J.; Mathies, R.A. Microfluidic linear hydrogel array for multiplexed single nucleotide polymorphism (SNP) detection. Anal. Chem. 2015, 87, 3165-3170.
-
(2015)
Anal. Chem.
, vol.87
, pp. 3165-3170
-
-
Jung, Y.K.1
Kim, J.2
Mathies, R.A.3
-
232
-
-
60149111910
-
Peg hydrogels for the controlled release of biomolecules in regenerative medicine
-
Lin, C.-C.; Anseth, K. Peg hydrogels for the controlled release of biomolecules in regenerative medicine. Pharm. Res. 2009, 26, 631-643.
-
(2009)
Pharm. Res.
, vol.26
, pp. 631-643
-
-
Lin, C.-C.1
Anseth, K.2
-
233
-
-
41549148288
-
Hydrogels in drug delivery: Progress and challenges
-
Hoare, T.R.; Kohane, D.S. Hydrogels in drug delivery: Progress and challenges. Polymer 2008, 49, 1993-2007.
-
(2008)
Polymer
, vol.49
, pp. 1993-2007
-
-
Hoare, T.R.1
Kohane, D.S.2
-
234
-
-
77949420619
-
Hydrogel functionalization with DNA aptamers for sustained pdgf-bb release
-
Soontornworajit, B.; Zhou, J.; Shaw, M.T.; Fan, T.-H.; Wang, Y. Hydrogel functionalization with DNA aptamers for sustained pdgf-bb release. Chem. Commun. 2010, 46, 1857-1859.
-
(2010)
Chem. Commun.
, vol.46
, pp. 1857-1859
-
-
Soontornworajit, B.1
Zhou, J.2
Shaw, M.T.3
Fan, T.-H.4
Wang, Y.5
-
235
-
-
77955903047
-
A hybrid particle-hydrogel composite for oligonucleotide-mediated pulsatile protein release
-
Soontornworajit, B.; Zhou, J.; Wang, Y. A hybrid particle-hydrogel composite for oligonucleotide-mediated pulsatile protein release. Soft Matter 2010, 6, 4255-4261.
-
(2010)
Soft Matter
, vol.6
, pp. 4255-4261
-
-
Soontornworajit, B.1
Zhou, J.2
Wang, Y.3
-
236
-
-
79960558527
-
Affinity hydrogels for controlled protein release using nucleic acid aptamers and complementary oligonucleotides
-
Soontornworajit, B.; Zhou, J.; Snipes, M.P.; Battig, M.R.; Wang, Y. Affinity hydrogels for controlled protein release using nucleic acid aptamers and complementary oligonucleotides. Biomaterials 2011, 32, 6839-6849.
-
(2011)
Biomaterials
, vol.32
, pp. 6839-6849
-
-
Soontornworajit, B.1
Zhou, J.2
Snipes, M.P.3
Battig, M.R.4
Wang, Y.5
-
237
-
-
84866676026
-
Programmable hydrogels for controlled cell catch and release using hybridized aptamers and complementary sequences
-
Zhang, Z.; Chen, N.; Li, S.; Battig, M.R.; Wang, Y. Programmable hydrogels for controlled cell catch and release using hybridized aptamers and complementary sequences. J. Am. Chem. Soc. 2012, 134, 15716-15719.
-
(2012)
J. Am. Chem. Soc.
, vol.134
, pp. 15716-15719
-
-
Zhang, Z.1
Chen, N.2
Li, S.3
Battig, M.R.4
Wang, Y.5
-
238
-
-
83355169564
-
Cell adhesion on an artificial extracellular matrix using aptamer-functionalized peg hydrogels
-
Chen, N.; Zhang, Z.; Soontornworajit, B.; Zhou, J.; Wang, Y. Cell adhesion on an artificial extracellular matrix using aptamer-functionalized peg hydrogels. Biomaterials 2012, 33, 1353-1362.
-
(2012)
Biomaterials
, vol.33
, pp. 1353-1362
-
-
Chen, N.1
Zhang, Z.2
Soontornworajit, B.3
Zhou, J.4
Wang, Y.5
-
239
-
-
84940181679
-
Precision oncology for patients with advanced cancer: The challenges of malignant snowflakes
-
in press
-
Kurzrock, R.; Giles, F.J. Precision oncology for patients with advanced cancer: The challenges of malignant snowflakes. Cell Cycle 2015, in press.
-
(2015)
Cell Cycle
-
-
Kurzrock, R.1
Giles, F.J.2
-
240
-
-
84860359497
-
Toward Precision Medicine: A New Social Contract?
-
Desmond-Hellmann, S. Toward Precision Medicine: A New Social Contract? Sci. Transl. Med. 2012, 4, doi:10.1126/scitranslmed.3003473.
-
(2012)
Sci. Transl. Med.
, vol.4
-
-
Desmond-Hellmann, S.1
-
241
-
-
84930439209
-
The precision medicine initiative: A new national effort
-
Ashley, E.A. The precision medicine initiative: A new national effort. JAMA 2015, 313, 2119-2120.
-
(2015)
JAMA
, vol.313
, pp. 2119-2120
-
-
Ashley, E.A.1
-
242
-
-
0036107889
-
Discovery of novel tumor markers of pancreatic cancer using global gene expression technology
-
Iacobuzio-Donahue, C.A.; Maitra, A.; Shen-Ong, G.L.; van Heek, T.; Ashfaq, R.; Meyer, R.; Walter, K.; Berg, K.; Hollingsworth, M.A.; Cameron, J.L.; et al. Discovery of novel tumor markers of pancreatic cancer using global gene expression technology. Am. J. Pathol. 2002, 160, 1239-1249.
-
(2002)
Am. J. Pathol.
, vol.160
, pp. 1239-1249
-
-
Iacobuzio-Donahue, C.A.1
Maitra, A.2
Shen-Ong, G.L.3
van Heek, T.4
Ashfaq, R.5
Meyer, R.6
Walter, K.7
Berg, K.8
Hollingsworth, M.A.9
Cameron, J.L.10
-
243
-
-
84877306864
-
Metabolomics for tumor marker discovery and identification based on chromatography-mass spectrometry
-
Yin, P.; Xu, G. Metabolomics for tumor marker discovery and identification based on chromatography-mass spectrometry. Expert Rev. Mol. Diagn. 2013, 13, 339-348.
-
(2013)
Expert Rev. Mol. Diagn.
, vol.13
, pp. 339-348
-
-
Yin, P.1
Xu, G.2
-
244
-
-
84896778540
-
Discovery of tumor markers for gastric cancer by proteomics
-
Wu, J.-Y.; Cheng, C.-C.; Wang, J.-Y.; Wu, D.-C.; Hsieh, J.-S.; Lee, S.-C.; Wang, W.-M. Discovery of tumor markers for gastric cancer by proteomics. PLoS ONE 2014, 9, doi:10.1371/ journal.pone.0084158
-
(2014)
PLoS ONE
, vol.9
-
-
Wu, J.-Y.1
Cheng, C.-C.2
Wang, J.-Y.3
Wu, D.-C.4
Hsieh, J.-S.5
Lee, S.-C.6
Wang, W.-M.7
-
245
-
-
84924918503
-
Discovery of prognostic biomarkers for predicting lung cancer metastasis using microarray and survival data
-
Huang, H.-L.; Wu, Y.-C.; Su, L.-J.; Huang, Y.-J.; Charoenkwan, P.; Chen, W.-L.; Lee, H.-C.; Chu, W.C.-C.; Ho, S.-Y. Discovery of prognostic biomarkers for predicting lung cancer metastasis using microarray and survival data. BMC Bioinform. 2015, 16, 54.
-
(2015)
BMC Bioinform.
, vol.16
, pp. 54
-
-
Huang, H.-L.1
Wu, Y.-C.2
Su, L.-J.3
Huang, Y.-J.4
Charoenkwan, P.5
Chen, W.-L.6
Lee, H.-C.7
Chu, W.C.-C.8
Ho, S.-Y.9
-
246
-
-
84930520177
-
Validation of new cancer biomarkers: A position statement from the european group on tumor markers
-
Duffy, M.J.; Sturgeon, C.M.; Sölétormos, G.; Barak, V.; Molina, R.; Hayes, D.F.; Diamandis, E.P.; Bossuyt, P.M.M. Validation of new cancer biomarkers: A position statement from the european group on tumor markers. Clin. Chem. 2015, 61, 809-820.
-
(2015)
Clin. Chem.
, vol.61
, pp. 809-820
-
-
Duffy, M.J.1
Sturgeon, C.M.2
Sölétormos, G.3
Barak, V.4
Molina, R.5
Hayes, D.F.6
Diamandis, E.P.7
Bossuyt, P.M.M.8
-
247
-
-
84887114555
-
The HER2 receptor in breast cancer: Pathophysiology, clinical use, and new advances in therapy
-
Mitri, Z.; Constantine, T.; O'Regan, R. The HER2 receptor in breast cancer: Pathophysiology, clinical use, and new advances in therapy. Chemother. Res. Pract. 2012, 2012, 743193.
-
(2012)
Chemother. Res. Pract.
, vol.2012
-
-
Mitri, Z.1
Constantine, T.2
O'Regan, R.3
-
248
-
-
84856561902
-
Screening for prostate cancer: The current evidence and guidelines controversy
-
Gomella, L.G.; Liu, X.S.; Trabulsi, E.J.; Kelly, W.K.; Myers, R.; Showalter, T.; Dicker, A.; Wender, R. Screening for prostate cancer: The current evidence and guidelines controversy. Can. J. Urol. 2011, 18, 5875-5883.
-
(2011)
Can. J. Urol.
, vol.18
, pp. 5875-5883
-
-
Gomella, L.G.1
Liu, X.S.2
Trabulsi, E.J.3
Kelly, W.K.4
Myers, R.5
Showalter, T.6
Dicker, A.7
Wender, R.8
-
249
-
-
30744470421
-
New tumor markers: CA125 and beyond
-
Bast, R.C.; Badgwell, D.; Lu, Z.; Marquez, R.; Rosen, D.; Liu, J.; Baggerly, K.A.; Atkinson, E.N.; Skates, S.; Zhang, Z.; et al. New tumor markers: CA125 and beyond. Int. J. Gynecol. Cancer 2005, 15, 274-281.
-
(2005)
Int. J. Gynecol. Cancer
, vol.15
, pp. 274-281
-
-
Bast, R.C.1
Badgwell, D.2
Lu, Z.3
Marquez, R.4
Rosen, D.5
Liu, J.6
Baggerly, K.A.7
Atkinson, E.N.8
Skates, S.9
Zhang, Z.10
-
250
-
-
78149249388
-
Personalized medicine in non-small-cell lung cancer: Is K-Ras a useful marker in selecting patients for epidermal growth factor receptor-targeted therapy?
-
Roberts, P.J.; Stinchcombe, T.E.; Der, C.J.; Socinski, M.A. Personalized medicine in non-small-cell lung cancer: Is K-Ras a useful marker in selecting patients for epidermal growth factor receptor-targeted therapy? J. Clin. Oncol. 2010, 28, 4769-4777.
-
(2010)
J. Clin. Oncol.
, vol.28
, pp. 4769-4777
-
-
Roberts, P.J.1
Stinchcombe, T.E.2
Der, C.J.3
Socinski, M.A.4
-
251
-
-
77953688634
-
Clinicopathological and protein characterization of braf- and k-ras-mutated colorectal cancer and implications for prognosis
-
Zlobec, I.; Bihl, M.P.; Schwarb, H.; Terracciano, L.; Lugli, A. Clinicopathological and protein characterization of braf- and k-ras-mutated colorectal cancer and implications for prognosis. Int. J. Cancer 2010, 127, 367-380.
-
(2010)
Int. J. Cancer
, vol.127
, pp. 367-380
-
-
Zlobec, I.1
Bihl, M.P.2
Schwarb, H.3
Terracciano, L.4
Lugli, A.5
-
252
-
-
33750619876
-
Posttranslational protein modifications: Current implications for cancer detection, prevention, and therapeutics
-
Krueger, K.E.; Srivastava, S. Posttranslational protein modifications: Current implications for cancer detection, prevention, and therapeutics. Mol. Cell. Proteomics 2006, 5, 1799-1810.
-
(2006)
Mol. Cell. Proteomics
, vol.5
, pp. 1799-1810
-
-
Krueger, K.E.1
Srivastava, S.2
-
253
-
-
84864000455
-
Small changes huge impact: The role of protein posttranslational modifications in cellular homeostasis and disease
-
2011
-
Karve, T.M.; Cheema, A.K. Small changes huge impact: The role of protein posttranslational modifications in cellular homeostasis and disease. J. Amino Acids 2011, 2011.
-
(2011)
J. Amino Acids
-
-
Karve, T.M.1
Cheema, A.K.2
-
254
-
-
0029820183
-
An enzyme-linked oligonucleotide assay
-
Drolet, D.W.; Moon-McDermott, L.; Romig, T.S. An enzyme-linked oligonucleotide assay. Nat. Biotechnol. 1996, 14, 1021-1025.
-
(1996)
Nat. Biotechnol.
, vol.14
, pp. 1021-1025
-
-
Drolet, D.W.1
Moon-McDermott, L.2
Romig, T.S.3
-
255
-
-
84879128426
-
Tumor marker detection by aptamer-functionalized graphene oxide
-
Lin, M.-Y.; Lu, Y.-P.; Mihai Grumezescu, A.; Han Ho, F.; Kao, Y.-H.; Yang, Y.-S.; Yang, C.-H. Tumor marker detection by aptamer-functionalized graphene oxide. Curr. Org. Chem. 2013, 17, 132-136.
-
(2013)
Curr. Org. Chem.
, vol.17
, pp. 132-136
-
-
Lin, M.-Y.1
Lu, Y.-P.2
Mihai Grumezescu, A.3
Han Ho, F.4
Kao, Y.-H.5
Yang, Y.-S.6
Yang, C.-H.7
-
256
-
-
78650149915
-
Aptamer-based multiplexed proteomic technology for biomarker discovery
-
Gold, L.; Ayers, D.; Bertino, J.; Bock, C.; Bock, A.; Brody, E.N.; Carter, J.; Dalby, A.B.; Eaton, B.E.; Fitzwater, T.; et al. Aptamer-based multiplexed proteomic technology for biomarker discovery. PLoS ONE 2010, 5, doi:10.1371/journal.pone.0015004.
-
(2010)
PLoS ONE
, vol.5
-
-
Gold, L.1
Ayers, D.2
Bertino, J.3
Bock, C.4
Bock, A.5
Brody, E.N.6
Carter, J.7
Dalby, A.B.8
Eaton, B.E.9
Fitzwater, T.10
-
257
-
-
78650121234
-
Unlocking biomarker discovery: Large scale application of aptamer proteomic technology for early detection of lung cancer
-
Ostroff, R.M.; Bigbee, W.L.; Franklin, W.; Gold, L.; Mehan, M.; Miller, Y.E.; Pass, H.I.; Rom, W.N.; Siegfried, J.M.; Stewart, A.; et al. Unlocking biomarker discovery: Large scale application of aptamer proteomic technology for early detection of lung cancer. PLoS ONE 2010, 5, doi:10.1371/journal.pone.0015003
-
(2010)
PLoS ONE
, vol.5
-
-
Ostroff, R.M.1
Bigbee, W.L.2
Franklin, W.3
Gold, L.4
Mehan, M.5
Miller, Y.E.6
Pass, H.I.7
Rom, W.N.8
Siegfried, J.M.9
Stewart, A.10
-
258
-
-
84904288233
-
Nucleic acid aptamers for living cell analysis
-
Xiong, X.; Lv, Y.; Chen, T.; Zhang, X.; Wang, K.; Tan, W. Nucleic acid aptamers for living cell analysis. Annu. Rev. Anal. Chem. 2014, 7, 405-426.
-
(2014)
Annu. Rev. Anal. Chem.
, vol.7
, pp. 405-426
-
-
Xiong, X.1
Lv, Y.2
Chen, T.3
Zhang, X.4
Wang, K.5
Tan, W.6
-
259
-
-
84899796713
-
Aptamer-based biosensors for biomedical diagnostics
-
Zhou, W.; Huang, P.-J.; Ding, J.; Liu, J. Aptamer-based biosensors for biomedical diagnostics. Analyst 2014, 139, 2627-2640.
-
(2014)
Analyst
, vol.139
, pp. 2627-2640
-
-
Zhou, W.1
Huang, P.-J.2
Ding, J.3
Liu, J.4
-
260
-
-
84907621399
-
Aptamers as a replacement for antibodies in enzyme-linked immunosorbent assay
-
Toh, S.Y.; Citartan, M.; Gopinath, S.C.B.; Tang, T.-H. Aptamers as a replacement for antibodies in enzyme-linked immunosorbent assay. Biosens. Bioelectron. 2015, 64, 392-403.
-
(2015)
Biosens. Bioelectron.
, vol.64
, pp. 392-403
-
-
Toh, S.Y.1
Citartan, M.2
Gopinath, S.C.B.3
Tang, T.-H.4
|