메뉴 건너뛰기




Volumn 127, Issue 2, 2010, Pages 367-380

Clinicopathological and protein characterization of BRAF- and K-RAS-mutated colorectal cancer and implications for prognosis

Author keywords

BRAF; Colorectal cancer; MSI; Prognosis

Indexed keywords

B RAF KINASE; BIOLOGICAL MARKER; K RAS PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PARAFFIN; PROTEIN KINASE B; RAS PROTEIN; TRANSCRIPTION FACTOR CDX2; TRANSFORMING GROWTH FACTOR BETA; WNT PROTEIN; BRAF PROTEIN, HUMAN; KRAS PROTEIN, HUMAN; ONCOPROTEIN;

EID: 77953688634     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.25042     Document Type: Article
Times cited : (155)

References (38)
  • 1
    • 17844368327 scopus 로고    scopus 로고
    • The MAPK signalling pathways and colorectal cancer
    • Fang JY, Richardson BC. The MAPK signalling pathways and colorectal cancer. Lancet Oncol 2005;6:322-7.
    • (2005) Lancet Oncol , vol.6 , pp. 322-327
    • Fang, J.Y.1    Richardson, B.C.2
  • 3
    • 33845608798 scopus 로고    scopus 로고
    • Classification of colorectal cancer based on correlation of clinical, morphological and molecular features
    • Jass JR. Classification of colorectal cancer based on correlation of clinical, morphological and molecular features. Histopathology 2007;50:113-30.
    • (2007) Histopathology , vol.50 , pp. 113-130
    • Jass, J.R.1
  • 5
    • 67649652208 scopus 로고    scopus 로고
    • BRAF mutation in metastatic colorectal cancer
    • Tol J, Nagtegaal ID, Punt CJ. BRAF mutation in metastatic colorectal cancer. N Engl J Med 2009;361:98-9.
    • (2009) N Engl J Med , vol.361 , pp. 98-99
    • Tol, J.1    Nagtegaal, I.D.2    Punt, C.J.3
  • 9
    • 45549090492 scopus 로고    scopus 로고
    • Clinicopathologic characteristics. CpG island methylator phenotype, and BRAF mutations in microsatellite-stable colorectal cancers without chromosomal instability
    • Kakar S, Deng G, Sahai V, Matsuzaki K, Tanaka H, Miura S, Kim YS. Clinicopathologic characteristics. CpG island methylator phenotype, and BRAF mutations in microsatellite-stable colorectal cancers without chromosomal instability. Arch Pathol Lab Med 2008;132:958-64.
    • (2008) Arch Pathol Lab Med , vol.132 , pp. 958-964
    • Kakar, S.1    Deng, G.2    Sahai, V.3    Matsuzaki, K.4    Tanaka, H.5    Miura, S.6    Kim, Y.S.7
  • 11
    • 44449146998 scopus 로고    scopus 로고
    • Proximal and distal colorectal cancers show distinct gene-specific methylation profiles and clinical and molecular characteristics
    • Deng G, Kakar S, Tanaka H, Matsuzaki K, Miura S, Sleisenger MH, Kim YS. Proximal and distal colorectal cancers show distinct gene-specific methylation profiles and clinical and molecular characteristics. Eur J Cancer 2008;44:1290-301.
    • (2008) Eur J Cancer , vol.44 , pp. 1290-1301
    • Deng, G.1    Kakar, S.2    Tanaka, H.3    Matsuzaki, K.4    Miura, S.5    Sleisenger, M.H.6    Kim, Y.S.7
  • 12
    • 67650552462 scopus 로고    scopus 로고
    • Divergent oncogenic changes influence survival differences between colon and rectal adenocarcinomas
    • Kalady MF, Sanchez JA, Manilich E, Hammel J, Casey G, Church JM. Divergent oncogenic changes influence survival differences between colon and rectal adenocarcinomas. Dis Colon Rectum 2009;52:1039-45.
    • (2009) Dis Colon Rectum , vol.52 , pp. 1039-1045
    • Kalady, M.F.1    Sanchez, J.A.2    Manilich, E.3    Hammel, J.4    Casey, G.5    Church, J.M.6
  • 17
    • 63149098775 scopus 로고    scopus 로고
    • Distinct BRAF (V600E) and KRAS mutations in high microsatellite instability sporadic colorectal cancer in African Americans
    • Kumar K, Brim H, Giardiello F, Smoot DT, Nouraie M, Lee EL, Ashktorab H. Distinct BRAF (V600E) and KRAS mutations in high microsatellite instability sporadic colorectal cancer in African Americans. Clin Cancer Res 2009;15:1155-61.
    • (2009) Clin Cancer Res , vol.15 , pp. 1155-1161
    • Kumar, K.1    Brim, H.2    Giardiello, F.3    Smoot, D.T.4    Nouraie, M.5    Lee, E.L.6    Ashktorab, H.7
  • 27
    • 0022453271 scopus 로고
    • The grading of rectal cancer: Historical perspectives and a multivariate analysis of 447 cases
    • Jass JR, Atkin WS, Cuzick J, Bussey HJ, Morson BC, Northover JM, Todd IP. The grading of rectal cancer: historical perspectives and a multivariate analysis of 447 cases. Histopathology 1986;10:437-59. (Pubitemid 16039125)
    • (1986) Histopathology , vol.10 , Issue.5 , pp. 437-459
    • Jass, J.R.1    Atkin, W.S.2    Cuzick, J.3
  • 29
    • 52649176459 scopus 로고    scopus 로고
    • Role of RHAMM within the hierarchy of well-established prognostic factors in colorectal cancer
    • Zlobec I, Terracciano L, Tornillo L, Gunthert U, Vuong T, Jass JR, Lugli A. Role of RHAMM within the hierarchy of well-established prognostic factors in colorectal cancer. Gut 2008;57:1413-19.
    • (2008) Gut , vol.57 , pp. 1413-1419
    • Zlobec, I.1    Terracciano, L.2    Tornillo, L.3    Gunthert, U.4    Vuong, T.5    Jass, J.R.6    Lugli, A.7
  • 30
    • 57749112183 scopus 로고    scopus 로고
    • Differential diagnostic and functional role of the multi-marker phenotype CDX2/CK20/CK7 in colorectal cancer stratified by mismatch repair status
    • Lugli A, Tzankov A, Zlobec I, Terracciano LM. Differential diagnostic and functional role of the multi-marker phenotype CDX2/CK20/CK7 in colorectal cancer stratified by mismatch repair status. Mod Pathol 2008;21:1403-12.
    • (2008) Mod Pathol , vol.21 , pp. 1403-1412
    • Lugli, A.1    Tzankov, A.2    Zlobec, I.3    Terracciano, L.M.4
  • 31
    • 0023213901 scopus 로고
    • A new prognostic classification of rectal cancer
    • Jass JR, Love SB, Northover JM. A new prognostic classification of rectal cancer. Lancet 1987;1:1303-6.
    • (1987) Lancet , vol.1 , pp. 1303-1306
    • Jass, J.R.1    Love, S.B.2    Northover, J.M.3
  • 32
    • 33846577890 scopus 로고    scopus 로고
    • Differential significance of tumour infiltrating lymphocytes in sporadic mismatch repair deficient versus proficient colorectal cancers: A potential role for dysregulation of the transforming growth factor-beta pathway
    • DOI 10.1016/j.ejca.2006.11.012, PII S0959804906010264
    • Baker K, Zlobec I, Tornillo L, Terracciano L, Jass JR, Lugli A. Differential significance of tumour infiltrating lymphocytes in sporadic mismatch repair deficient versus proficient colorectal cancers: a potential role for dysregulation of the transforming growth factor-beta pathway. Eur J Cancer 2007;43:624-31. (Pubitemid 46178541)
    • (2007) European Journal of Cancer , vol.43 , Issue.3 , pp. 624-631
    • Baker, K.1    Zlobec, I.2    Tornillo, L.3    Terracciano, L.4    Jass, J.R.5    Lugli, A.6
  • 33
    • 4644229375 scopus 로고    scopus 로고
    • The role of Cdx genes in the mammalian gut
    • DOI 10.1136/gut.2003.038240
    • Beck F. The role of Cdx genes in the mammalian gut. Gut 2004;53:1394-6. (Pubitemid 39265253)
    • (2004) Gut , vol.53 , Issue.10 , pp. 1394-1396
    • Beck, F.1
  • 34
    • 0141869045 scopus 로고    scopus 로고
    • The Cdx2 homeobox gene has a tumour suppressor function in the distal colon in addition to a homeotic role during gut development
    • DOI 10.1136/gut.52.10.1465
    • Bonhomme C, Duluc I, Martin E, Chawengsaksophak K, Chenard MP, Kedinger M, Beck F, Freund JN, Domon-Dell C. The Cdx2 homeobox gene has a tumour suppressor function in the distal colon in addition to a homeotic role during gut development. Gut 2003;52:1465-71. (Pubitemid 37176727)
    • (2003) Gut , vol.52 , Issue.10 , pp. 1465-1471
    • Bonhomme, C.1    Duluc, I.2    Martin, E.3    Chawengsaksophak, K.4    Chenard, M.-P.5    Kedinger, M.6    Beck, F.7    Freund, J.-N.8    Domon-Dell, C.9
  • 35
    • 53149097362 scopus 로고    scopus 로고
    • BRAF, KRAS and PIK3CA mutations in colorectal serrated polyps and cancer: Primary or secondary genetic events in colorectal carcinogenesis?
    • Velho S, Moutinho C, Cirnes L, Albuquerque C, Hamelin R, Schmitt F, Carneiro F, Oliveira C, Seruca R. BRAF, KRAS and PIK3CA mutations in colorectal serrated polyps and cancer: primary or secondary genetic events in colorectal carcinogenesis? BMC Cancer 2008;8:255.
    • (2008) BMC Cancer , vol.8 , pp. 255
    • Velho, S.1    Moutinho, C.2    Cirnes, L.3    Albuquerque, C.4    Hamelin, R.5    Schmitt, F.6    Carneiro, F.7    Oliveira, C.8    Seruca, R.9
  • 36
    • 57349089198 scopus 로고    scopus 로고
    • Distinct CpG island methylation profiles and BRAF mutation status in serrated and adenomatous colorectal polyps
    • Kim YH, Kakar S, Cun L, Deng G, Kim YS. Distinct CpG island methylation profiles and BRAF mutation status in serrated and adenomatous colorectal polyps. Int J Cancer 2008;123:2587-93.
    • (2008) Int J Cancer , vol.123 , pp. 2587-2593
    • Kim, Y.H.1    Kakar, S.2    Cun, L.3    Deng, G.4    Kim, Y.S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.