Affinity hydrogels for controlled protein release using nucleic acid aptamers and complementary oligonucleotides

Biomaterials

Volumn 32, Issue 28, 2011, Pages 6839-6849

  Soontornworajit, Boonchoy ^a   Zhou, Jing ^a   Snipes, Matthew P ^a   Battig, Mark R ^a   Wang, Yong ^a  

^a UNIVERSITY OF CONNECTICUT   (United States)

Author keywords

Affinity; Controlled drug release; Drug delivery; Growth factor; Hydrogel

Indexed keywords

AFFINITY; APTAMERS; BOUND PROTEINS; CONTROLLED DRUG RELEASE; GROWTH FACTOR; HUMAN DISEASE; NEW STRATEGY; NUCLEIC ACID APTAMERS; PRECISE CONTROL; PROTEIN DRUGS; PROTEIN RELEASE; SYNERGISTIC EFFECT; TIME POINTS;

DISEASE CONTROL; DISSOCIATION; DRUG DELIVERY; NUCLEIC ACIDS; OLIGONUCLEOTIDES; PROTEINS;

HYDROGELS;

APTAMER; OLIGONUCLEOTIDE;

ARTICLE; BINDING AFFINITY; CONTROLLED DRUG RELEASE; DISSOCIATION; DRUG DELIVERY SYSTEM; GEL ELECTROPHORESIS; HYDROGEL; MOLECULAR HYBRIDIZATION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; PROTEIN SECRETION; SURFACE PLASMON RESONANCE;

APTAMERS, NUCLEOTIDE; BASE SEQUENCE; BIOCOMPATIBLE MATERIALS; HUMANS; HYDROGELS; MATERIALS TESTING; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; OLIGONUCLEOTIDES; POLYETHYLENE GLYCOLS; PROTEINS;

EID: 79960558527     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2011.05.074     Document Type: Article

References (58)

1. Place E.S., Evans N.D., Stevens M.M. Complexity in biomaterials for tissue engineering. Nature Mater 2009, 8:457-470.
2. Karp J.M., Langer R. Development and therapeutic applications of advanced biomaterials. Curr Opin Biotech 2007, 18:454-459.
3. Williams D.F. On the nature of biomaterials. Biomaterials 2009, 30:5897-5909.
4. Peppas N.A., Hilt J.Z., Khademhosseini A., Langer R. Hydrogels in biology and medicine: from molecular principles to bionanotechnology. Adv Mater 2006, 18:1345-1360.
5. Jia X.Q., Kiick K.L. Hybrid multicomponent hydrogels for tissue engineering. Macromol Biosci 2009, 9:140-156.
6. Lin C.C., Anseth K.S. PEG hydrogels for the controlled release of biomolecules in regenerative medicine. Pharm Res 2009, 26:631-643.
7. Prestwich G.D. Evaluating drug efficacy and toxicology in three dimensions: using synthetic extracellular matrices in drug discovery. Acc Chem Res 2008, 41:139-148.
8. Holmes T.C., de Lacalle S., Su X., Liu G., Rich A., Zhang S. Extensive neurite outgrowth and active synapse formation on self-assembling peptide scaffolds. P Natl Acad Sci USA 2000, 97:6728-6733.
9. Kisiday J., Jin M., Kurz B., Hung H., Semino C., Zhang S., et al. Self-assembling peptide hydrogel fosters chondrocyte extracellular matrix production and cell division: implications for cartilage tissue repair. P Natl Acad Sci USA 2002, 99:9996-10001.
10. Nowak A.P., Breedveld V., Pakstis L., Ozbas B., Pine D.J., Pochan D., et al. Rapidly recovering hydrogel scaffolds from self-assembling diblock copolypeptide amphiphiles. Nature 2002, 417:424-428.
11. Silva G.A., Czeisler C., Niece K.L., Beniash E., Harrington D.A., Kessler J.A., et al. Selective differentiation of neural progenitor cells by high-epitope density nanofibers. Science 2004, 303:1352-1355.
12. Guan J., Hong Y., Ma Z., Wagner W.R. Protein-reactive, thermoresponsive copolymers with high flexibility and biodegradability. Biomacromolecules 2008, 9:1283-1292.
13. Chaterji S., Kwon I.K., Park K. Smart polymeric gels: redefining the limits of biomedical devices. Prog Polym Sci 2007, 32:1083-1122.
14. Um S.H., Lee J.B., Park N., Kwon S.Y., Umbach C.C., Luo D. Enzyme-catalysed assembly of DNA hydrogel. Nat Mater 2006, 5:797-801.
15. Vepari C., Kaplan D.L. Silk as a biomaterial. Prog Polym Science 2007, 32:991-1007.
16. Hoare T.R., Kohane D.S. Hydrogels in drug delivery: progress and challenges. Polymer 2008, 49:1993-2007.
17. Lee J.B., Roh Y.H., Um S.H., Funabashi H., Cheng W.L., Cha J.J., et al. Multifunctional nanoarchitectures from DNA-based ABC monomers. Nat Nanotechnol 2009, 4:430-436.
18. Ellington A.D., Szostak J.W. In vitro selection of RNA molecules that bind specific ligands. Nature 1990, 346:818-822.
19. Tuerk C., Gold L. Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase. Science 1990, 249:505-510.
20. Soontornworajit B., Wang Y. Nucleic acid aptamers for clinical diagnosis: cell detection and molecular imaging. Anal Bioanal Chem 2011, 399:1591-1599.
21. Mayer G. The chemical biology of aptamers. Angew Chem Int Ed 2009, 48:2672-2689.
22. Wu Z.S., Zheng F., Shen G.L., Yu R.Q. A hairpin aptamer-based electrochemical biosensing platform for the sensitive detection of proteins. Biomaterials 2009, 30:2950-2955.
23. Carrasquilla C., Li Y.F., Brennan J.D. Surface immobilization of structure-switching DNA aptamers on macroporous sol-gel-derived films for solid-phase biosensing applications. Anal Chem 2011, 83:957-965.
24. Baeissa A., Dave N., Smith B.D., Liu J.W. DNA-functionalized monolithic hydrogels and gold nanoparticles for colorimetric DNA detection. Acs Appl Mater Inter 2010, 2:3594-3600.
25. Cho E.J., Collett J.R., Szafranska A.E., Ellington A.D. Optimization of aptamer microarray technology for multiple protein targets. Anal Chim Acta 2006, 564:82-90.
26. Feng L.Y., Chen Y., Ren J.S., Qu X.G. A graphene functionalized electrochemical aptasensor for selective label-free detection of cancer cells. Biomaterials 2011, 32:2930-2937.
27. Kwon O.S., Park S.J., Jang J. A high-performance VEGF aptamer functionalized polypyrrole nanotube biosensor. Biomaterials 2010, 31:4740-4747.
28. Cheng J., Teply B.A., Sherifi I., Sung J., Luther G., Gu F.X., et al. Formulation of functionalized PLGA-PEG nanoparticles for in vivo targeted drug delivery. Biomaterials 2007, 28:869-876.
29. Farokhzad O.C., Jon S.Y., Khademhosseini A., Tran T.N.T., LaVan D.A., Langer R. Nanopartide-aptamer bioconjugates: a new approach for targeting prostate cancer cells. Cancer Res 2004, 64:7668-7672.
30. Min K., Jo H., Song K., Cho M., Chun Y.S., Jon S., et al. Dual-aptamer-based delivery vehicle of doxorubicin to both PSMA (+) and PSMA (-) prostate cancers. Biomaterials 2011, 32:2124-2132.
31. Ko H.Y., Choi K.J., Lee C.H., Kim S. A multimodal nanoparticle-based cancer imaging probe simultaneously targeting nucleolin, integrin alpha(v)beta(3) and tenascin-C proteins. Biomaterials 2011, 32:1130-1138.
32. Wan Y.A., Kim Y.T., Li N., Cho S.K., Bachoo R., Ellington A.D., et al. Surface-immobilized aptamers for cancer cell isolation and microscopic cytology. Cancer Res 2010, 70:9371-9380.
33. Abelow A.E., Schepelina O., White R.J., Vallee-Belisle A., Plaxco K.W., Zharov I. Biomimetic glass nanopores employing aptamer gates responsive to a small molecule. Chem Commun 2010, 46:7984-7986.
34. Guo K.T., Scharnweber D., Schwenzer B., Ziemer G., Wendel H.P. The effect of electrochemical functionalization of Ti-alloy surfaces by aptamer-based capture molecules on cell adhesion. Biomaterials 2007, 28:468-474.
35. Phillips J.A., Xu Y., Xia Z., Fan Z.H., Tan W.H. Enrichment of cancer cells using aptamers immobilized on a microfluidic channel. Anal Chem 2009, 81:1033-1039.
36. Cao Z.H., Tong R., Mishra A., Xu W.C., Wong G.C.L., Cheng J.J., et al. Reversible cell-specific drug delivery with aptamer-functionalized liposomes. Angew Chem Int Ed 2009, 48:6494-6498.
37. Rusconi C.P., Roberts J.D., Pitoc G.A., Nimjee S.M., White R.R., Quick G., et al. Antidote-mediated control of an anticoagulant aptamer in vivo. Nat Biotechnol 2004, 22:1423-1428.
38. Rusconi C.P., Scardino E., Layzer J., Pitoc G.A., Ortel T.L., Monroe D., et al. RNA aptamers as reversible antagonists of coagulation factor IXa. Nature 2002, 419:90-94.
39. Soontornworajit B., Zhou J., Wang Y. A hybrid particle-hydrogel composite for oligonucleotide-mediated pulsatile protein release. Soft Matter 2010, 6:4255-4261.
40. Soontornworajit B., Zhou J., Zhang Z.Y., Wang Y. Aptamer-functionalized in situ injectable hydrogel for controlled protein release. Biomacromolecules 2010, 11:2724-2730.
41. Soontornworajit B., Zhou J., Shaw M.T., Fan T.H., Wang Y. Hydrogel functionalization with DNA aptamers for sustained PDGF-BB release. Chem Commun 2010, 46:1857-1859.
42. Lee K., Silva E.A., Mooney D.J. Growth factor delivery-based tissue engineering: general approaches and a review of recent developments. J R Soc Interface 2011, 8:153-170.
43. Carmeliet P. Angiogenesis in health and disease. Nat Med 2003, 9:653-660.
44. Tyagi S., Kramer F.R. Molecular beacons: probes that fluoresce upon hybridization. Nat Biotechnol 1996, 14:303-308.
45. Dittmer W.U., Reuter A., Simmel F.C. A DNA-based machine that can cyclically bind and release thrombin. Angew Chem Int Ed 2004, 43:3550-3553.
46. Yang H.H., Liu H.P., Kang H.Z., Tan W.H. Engineering target-responsive hydrogels based on aptamer - target interactions. J Am Chem Soc 2008, 130:6320-6321.
47. Wei B., Cheng I., Luo K.Q., Mi Y.L. Capture and release of protein by a reversible DNA-induced sol-gel transition system. Angew Chem Int Ed 2008, 47:331-333.
48. Zhou J., Soontornworajit B., Snipes M.P., Wang Y. Structural prediction and binding analysis of hybridized aptamers. J Mol Recognit 2011, 24:119-126.
49. Kuo C.K., Ma P.X. Ionically crosslinked alginate hydrogels as scaffolds for tissue engineering: part 1. structure, gelation rate and mechanical properties. Biomaterials 2001, 22:511-521.
50. Cha C., Kim S.Y., Cao L., Kong H. Decoupled control of stiffness and permeability with a cell-encapsulating poly(ethylene glycol) dimethacrylate hydrogel. Biomaterials 2010, 31:4864-4871.
51. Wetmur J.G., Davidson N. Kinetics of renaturation of DNA. J Mol Biol 1968, 31:349-370.
52. Lee C.S., Davis R.W., Davidson N. A physical study by electron microscopy of the terminally reptitious, circularly permuted DNA from the coliphage particles of Escherichia coli 15. J Mol Biol 1970, 48:1-22.
53. Green C., Tibbetts C. Reassociation rate limited displacement of DNA strands by branch migration. Nucleic Acids Res 1981, 9:1905-1918.
54. Jayasena S.D. Aptamers: an emerging class of molecules that rival antibodies in diagnostics. Clin Chem 1999, 45:1628-1650.
55. Gold L., Polisky B., Uhlenbeck O., Yarus M. Diversity of oligonucleotide functions. Annu Rev Biochem 1995, 64:763-797.
56. Yang Y., Kochoyan M., Burgstaller P., Westhof E., Famulok M. Structural basis of ligand discrimination by two related RNA aptamers resolved by NMR spectroscopy. Science 1996, 272:1343-1347.
57. Zhou J., Battig M.R., Wang Y. Aptamer-based molecular recognition for biosensor development. Anal Bioanal Chem 2010, 398:2471-2480.
58. Zhao H., Greenwald R.B., Reddy P., Xia J., Peng P. A new platform for oligonucleotide delivery utilizing the PEG prodrug approach. Bioconjugate Chem 2005, 16:758-766.