Fluorescence enhancement upon G-quadruplex folding: Synthesis, structure, and biophysical characterization of a dansyl/cyclodextrin-tagged thrombin binding aptamer

Bioconjugate Chemistry

Volumn 24, Issue 11, 2013, Pages 1917-1927

  De Tito, Stefano ^a   Morvan, François ^b   Meyer, Albert ^b   Vasseur, Jean Jacques ^b   Cummaro, Annunziata ^a   Petraccone, Luigi ^a   Pagano, Bruno ^a   Novellino, Ettore ^a   Randazzo, Antonio ^a   Giancola, Concetta ^a   Montesarchio, Daniela ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b UNIVERSITÉ DE MONTPELLIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

COPPER COMPOUNDS; ENZYMES; FLUORESCENCE;

APTAMERS; AZIDE-ALKYNE CYCLOADDITION; BIOPHYSICAL CHARACTERIZATION; ENVIRONMENTALLY SENSITIVE; FLUORESCENCE ENHANCEMENT; FOLDINGS; G-QUADRUPLEXES; STRUCTURE CHARACTERIZATION; SYNTHESISED; THROMBIN BINDING;

CYCLODEXTRINS;

APTAMER; ASCORBIC ACID; AZIDE; BETA CYCLODEXTRIN; DANSYL CHLORIDE; GUANINE QUADRUPLEX; PHOSPHORAMIDOUS ACID DERIVATIVE; THROMBIN; THROMBIN BINDING APTAMER; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; ARTICLE; CIRCULAR DICHROISM; CONTROLLED STUDY; CYCLOADDITION; DIELECTRIC CONSTANT; DNA BINDING; DNA DETERMINATION; DNA STRUCTURE; DNA SYNTHESIS; FLUORESCENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROGEN BOND; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MODULATION; NUCLEAR EXPORT SIGNAL; NUCLEAR OVERHAUSER EFFECT; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STABILITY; PROTON NUCLEAR MAGNETIC RESONANCE; STOICHIOMETRY;

APTAMERS, NUCLEOTIDE; BETA-CYCLODEXTRINS; DANSYL COMPOUNDS; DNA; FLUORESCENCE; G-QUADRUPLEXES; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; NUCLEIC ACID CONFORMATION;

EID: 84888622849     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/bc400352s     Document Type: Article

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