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Volumn 102, Issue 1, 2014, Pages 49-59

Aptamer-conjugated magnetic nanoparticles enable efficient targeted detection of integrin αvβ3 via magnetic resonance imaging

Author keywords

angiogenesis; aptamer; integrin avb3; magnetic nanoparticle; magnetic resonance imaging

Indexed keywords

DIAGNOSIS; MAGNETIC RESONANCE IMAGING; TUMORS;

EID: 84888640357     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.34678     Document Type: Article
Times cited : (31)

References (77)
  • 1
    • 0030940283 scopus 로고    scopus 로고
    • Alpha v integrins as receptors for tumor targeting by circulating ligands
    • Pasqualini R, Koivunen E, Ruoslahti E,. Alpha v integrins as receptors for tumor targeting by circulating ligands. Nat Biotechnol 1997; 15 (6): 542-546.
    • (1997) Nat Biotechnol , vol.15 , Issue.6 , pp. 542-546
    • Pasqualini, R.1    Koivunen, E.2    Ruoslahti, E.3
  • 2
    • 0036488589 scopus 로고    scopus 로고
    • Role of integrins in cell invasion and migration
    • Hood JD, Cheresh DA,. Role of integrins in cell invasion and migration. Nat Rev Cancer 2002; 2 (2): 91-100.
    • (2002) Nat Rev Cancer , vol.2 , Issue.2 , pp. 91-100
    • Hood, J.D.1    Cheresh, D.A.2
  • 3
    • 0026770377 scopus 로고
    • Integrins: Versatility, modulation, and signaling in cell adhesion
    • Hynes R,. Integrins: Versatility, modulation, and signaling in cell adhesion. Cell 1992; 69: 11-25.
    • (1992) Cell , vol.69 , pp. 11-25
    • Hynes, R.1
  • 4
    • 77953079442 scopus 로고    scopus 로고
    • Multimodality tumor imaging targeting integrin alphavbeta3
    • Cai W, Sam Gambhir S, Chen X,. Multimodality tumor imaging targeting integrin alphavbeta3. Biotechniques 2005; 39 (6 suppl): S14-S25.
    • (2005) Biotechniques , vol.39 , Issue.6 SUPPL.
    • Cai, W.1    Sam Gambhir, S.2    Chen, X.3
  • 7
    • 18244376347 scopus 로고    scopus 로고
    • Noninvasive visualization of the activated alphavbeta3 integrin in cancer patients by positron emission tomography and [18F]Galacto-RGD
    • Haubner R, Weber WA, Beer AJ, Vabuliene E, Reim D, Sarbia M, Becker KF, Goebel M, Hein R, Wester HJ, et al. Noninvasive visualization of the activated alphavbeta3 integrin in cancer patients by positron emission tomography and [18F]Galacto-RGD. PLoS Med 2005; 2 (3): e70.
    • (2005) PLoS Med , vol.2 , Issue.3
    • Haubner, R.1    Weber, W.A.2    Beer, A.J.3    Vabuliene, E.4    Reim, D.5    Sarbia, M.6    Becker, K.F.7    Goebel, M.8    Hein, R.9    Wester, H.J.10
  • 9
    • 0031862889 scopus 로고    scopus 로고
    • Detection of tumor angiogenesis in vivo by alphaVbeta3-targeted magnetic resonance imaging
    • Sipkins DA, Cheresh DA, Kazemi MR, Nevin LM, Bednarski MD, Li KC,. Detection of tumor angiogenesis in vivo by alphaVbeta3-targeted magnetic resonance imaging. Nat Med 1998; 4 (5): 623-626.
    • (1998) Nat Med , vol.4 , Issue.5 , pp. 623-626
    • Sipkins, D.A.1    Cheresh, D.A.2    Kazemi, M.R.3    Nevin, L.M.4    Bednarski, M.D.5    Li, K.C.6
  • 10
    • 28444471558 scopus 로고    scopus 로고
    • New multifunctional molecular conjugate vector for targeting, imaging, and therapy of tumors
    • Garanger E, Boturyn D, Jin Z, Dumy P, Favrot MC, Coll JL,. New multifunctional molecular conjugate vector for targeting, imaging, and therapy of tumors. Mol Ther 2005; 12 (6): 1168-1175.
    • (2005) Mol Ther , vol.12 , Issue.6 , pp. 1168-1175
    • Garanger, E.1    Boturyn, D.2    Jin, Z.3    Dumy, P.4    Favrot, M.C.5    Coll, J.L.6
  • 14
    • 33745495366 scopus 로고    scopus 로고
    • A review: Integrin alphavbeta3-targeted molecular imaging and therapy in angiogenesis
    • Lim EH, Danthi N, Bednarski M, Li KC,. A review: Integrin alphavbeta3-targeted molecular imaging and therapy in angiogenesis. Nanomedicine 2005; 1 (2): 110-114.
    • (2005) Nanomedicine , vol.1 , Issue.2 , pp. 110-114
    • Lim, E.H.1    Danthi, N.2    Bednarski, M.3    Li, K.C.4
  • 15
    • 77149124266 scopus 로고    scopus 로고
    • High-affinity alphavbeta3 integrin targeted optical probe as a new imaging biomarker for early atherosclerosis: Initial studies in Watanabe rabbits
    • Heroux J, Gharib AM, Danthi NS, Cecchini S, Ohayon J, Pettigrew RI,. High-affinity alphavbeta3 integrin targeted optical probe as a new imaging biomarker for early atherosclerosis: Initial studies in Watanabe rabbits. Mol Imaging Biol 2010; 12 (1): 2-8.
    • (2010) Mol Imaging Biol , vol.12 , Issue.1 , pp. 2-8
    • Heroux, J.1    Gharib, A.M.2    Danthi, N.S.3    Cecchini, S.4    Ohayon, J.5    Pettigrew, R.I.6
  • 16
    • 4544382190 scopus 로고    scopus 로고
    • RGD-modified anti-CD3 antibodies redirect cytolytic capacity of cytotoxic T lymphocytes toward alphavbeta3-expressing endothelial cells
    • Schraa AJ, Kok RJ, Botter SM, Withoff S, Meijer DK, de Leij LF, Molema G,. RGD-modified anti-CD3 antibodies redirect cytolytic capacity of cytotoxic T lymphocytes toward alphavbeta3-expressing endothelial cells. Int J Cancer 2004; 112 (2): 279-285.
    • (2004) Int J Cancer , vol.112 , Issue.2 , pp. 279-285
    • Schraa, A.J.1    Kok, R.J.2    Botter, S.M.3    Withoff, S.4    Meijer, D.K.5    De Leij, L.F.6    Molema, G.7
  • 17
    • 77955496933 scopus 로고    scopus 로고
    • MMP-2 alters VEGF expression via alphaVbeta3 integrin-mediated PI3K/AKT signaling in A549 lung cancer cells
    • Chetty C, Lakka SS, Bhoopathi P, Rao JS,. MMP-2 alters VEGF expression via alphaVbeta3 integrin-mediated PI3K/AKT signaling in A549 lung cancer cells. Int J Cancer 2010; 127 (5): 1081-1095.
    • (2010) Int J Cancer , vol.127 , Issue.5 , pp. 1081-1095
    • Chetty, C.1    Lakka, S.S.2    Bhoopathi, P.3    Rao, J.S.4
  • 18
    • 69249189472 scopus 로고    scopus 로고
    • Multifunctional magnetic nanoparticles for medical imaging applications
    • Fang C, Zhang M,. Multifunctional magnetic nanoparticles for medical imaging applications. J Mater Chem 2009; 19: 6258-6266.
    • (2009) J Mater Chem , vol.19 , pp. 6258-6266
    • Fang, C.1    Zhang, M.2
  • 19
    • 78649442434 scopus 로고    scopus 로고
    • A multimodal nanoparticle-based cancer imaging probe simultaneously targeting nucleolin, integrin alphavbeta3 and tenascin-C proteins
    • Ko HY, Choi KJ, Lee CH, Kim S,. A multimodal nanoparticle-based cancer imaging probe simultaneously targeting nucleolin, integrin alphavbeta3 and tenascin-C proteins. Biomaterials 2011; 32 (4): 1130-1138.
    • (2011) Biomaterials , vol.32 , Issue.4 , pp. 1130-1138
    • Ko, H.Y.1    Choi, K.J.2    Lee, C.H.3    Kim, S.4
  • 21
    • 46749132642 scopus 로고    scopus 로고
    • Multifunctional magnetic nanoparticles for targeted imaging and therapy
    • McCarthy JR, Weissleder R,. Multifunctional magnetic nanoparticles for targeted imaging and therapy. Adv Drug Deliv Rev 2008; 60 (11): 1241-1251.
    • (2008) Adv Drug Deliv Rev , vol.60 , Issue.11 , pp. 1241-1251
    • McCarthy, J.R.1    Weissleder, R.2
  • 22
  • 23
    • 36048993546 scopus 로고    scopus 로고
    • Nanoplatforms for targeted molecular imaging in living subjects
    • Cai W, Chen X,. Nanoplatforms for targeted molecular imaging in living subjects. Small 2007; 3 (11): 1840-1854.
    • (2007) Small , vol.3 , Issue.11 , pp. 1840-1854
    • Cai, W.1    Chen, X.2
  • 24
    • 41649110649 scopus 로고    scopus 로고
    • Imaging in the era of molecular oncology
    • Weissleder R, Pittet MJ,. Imaging in the era of molecular oncology. Nature 2008; 452 (7187): 580-589.
    • (2008) Nature , vol.452 , Issue.7187 , pp. 580-589
    • Weissleder, R.1    Pittet, M.J.2
  • 25
    • 77957946615 scopus 로고    scopus 로고
    • Self-assembled fluorescent magnetic nanoprobes for multimode-biomedical imaging
    • Lim EK, Yang J, Dinney CP, Suh JS, Huh YM, Haam S,. Self-assembled fluorescent magnetic nanoprobes for multimode-biomedical imaging. Biomaterials 2010; 31 (35): 9310-9319.
    • (2010) Biomaterials , vol.31 , Issue.35 , pp. 9310-9319
    • Lim, E.K.1    Yang, J.2    Dinney, C.P.3    Suh, J.S.4    Huh, Y.M.5    Haam, S.6
  • 28
    • 38649108163 scopus 로고    scopus 로고
    • Ultrasensitive detection and molecular imaging with magnetic nanoparticles
    • Yang J, Gunn J, Dave SR, Zhang M, Wang YA, Gao X,. Ultrasensitive detection and molecular imaging with magnetic nanoparticles. Analyst 2008; 133 (2): 154-160.
    • (2008) Analyst , vol.133 , Issue.2 , pp. 154-160
    • Yang, J.1    Gunn, J.2    Dave, S.R.3    Zhang, M.4    Wang, Y.A.5    Gao, X.6
  • 30
    • 69249173020 scopus 로고    scopus 로고
    • Antibiofouling amphiphilic polymer-coated superparamagnetic iron oxide nanoparticles: Synthesis, characterization, and use in cancer imaging in vivo
    • Park J, Yu MK, Jeong YY, Kim JW, Lee K, Phan VN, Jon S,. Antibiofouling amphiphilic polymer-coated superparamagnetic iron oxide nanoparticles: Synthesis, characterization, and use in cancer imaging in vivo. J Mater Chem 2009; 19 (35): 6412.
    • (2009) J Mater Chem , vol.19 , Issue.35 , pp. 6412
    • Park, J.1    Yu, M.K.2    Jeong, Y.Y.3    Kim, J.W.4    Lee, K.5    Phan, V.N.6    Jon, S.7
  • 32
    • 4544266019 scopus 로고    scopus 로고
    • Iron oxide nanoparticles as magnetic resonance contrast agent for tumor imaging via folate receptor-targeted delivery
    • Choi H, Choi SR, Zhou R, Kung HF, Chen IW,. Iron oxide nanoparticles as magnetic resonance contrast agent for tumor imaging via folate receptor-targeted delivery. Acad Radiol 2004; 11 (9): 996-1004.
    • (2004) Acad Radiol , vol.11 , Issue.9 , pp. 996-1004
    • Choi, H.1    Choi, S.R.2    Zhou, R.3    Kung, H.F.4    Chen, I.W.5
  • 33
    • 39749193899 scopus 로고    scopus 로고
    • MRI detection of thrombin with aptamer functionalized superparamagnetic iron oxide nanoparticles
    • Yigit MV, Mazumdar D, Lu Y,. MRI detection of thrombin with aptamer functionalized superparamagnetic iron oxide nanoparticles. Bioconjugate Chem 2008; 19: 412-417.
    • (2008) Bioconjugate Chem , vol.19 , pp. 412-417
    • Yigit, M.V.1    Mazumdar, D.2    Lu, Y.3
  • 34
    • 0029311527 scopus 로고
    • A molecular receptor-binding contrast agent for magnetic resonance imaging of the liver
    • Vera DR, Buonocore MH, Wisner ER, Katzberg RW, Stadalnik RC,. A molecular receptor-binding contrast agent for magnetic resonance imaging of the liver. Acad Radiol 1995; 2 (6): 497-506.
    • (1995) Acad Radiol , vol.2 , Issue.6 , pp. 497-506
    • Vera, D.R.1    Buonocore, M.H.2    Wisner, E.R.3    Katzberg, R.W.4    Stadalnik, R.C.5
  • 35
    • 25644452128 scopus 로고    scopus 로고
    • Comparison of ultrasmall superparamagnetic iron oxide particles and low molecular weight contrast agents to detect rejecting transplanted hearts with magnetic resonance imaging
    • Penno E, Johnsson C, Johansson L, Ahlstrom H,. Comparison of ultrasmall superparamagnetic iron oxide particles and low molecular weight contrast agents to detect rejecting transplanted hearts with magnetic resonance imaging. Invest Radiol 2005; 40 (10): 648-654.
    • (2005) Invest Radiol , vol.40 , Issue.10 , pp. 648-654
    • Penno, E.1    Johnsson, C.2    Johansson, L.3    Ahlstrom, H.4
  • 38
    • 72849132710 scopus 로고    scopus 로고
    • Self-labeled magneto nanoprobes using tri-aminated polysorbate 80 for detection of human mesenchymal stem cells
    • Lim E-K, Yang J, Suh J-S, Huh Y-M, Haam S,. Self-labeled magneto nanoprobes using tri-aminated polysorbate 80 for detection of human mesenchymal stem cells. J Mater Chem 2009; 19 (47): 8958.
    • (2009) J Mater Chem , vol.19 , Issue.47 , pp. 8958
    • Lim, E.-K.1    Yang, J.2    Suh, J.-S.3    Huh, Y.-M.4    Haam, S.5
  • 39
    • 68249116152 scopus 로고    scopus 로고
    • Superparamagnetic iron oxide nanoparticles from preparations to in vivo MRI applications
    • Qiao R, Yang C, Gao M,. Superparamagnetic iron oxide nanoparticles from preparations to in vivo MRI applications. J Mater Chem 2009; 19: 6274-6293.
    • (2009) J Mater Chem , vol.19 , pp. 6274-6293
    • Qiao, R.1    Yang, C.2    Gao, M.3
  • 40
    • 0037180413 scopus 로고    scopus 로고
    • Targeted antiproliferative drug delivery to vascular smooth muscle cells with a magnetic resonance imaging nanoparticle contrast agent: Implications for rational therapy of restenosis
    • Lanza GM,. Targeted antiproliferative drug delivery to vascular smooth muscle cells with a magnetic resonance imaging nanoparticle contrast agent: Implications for rational therapy of restenosis. Circulation 2002; 106 (22): 2842-2847.
    • (2002) Circulation , vol.106 , Issue.22 , pp. 2842-2847
    • Lanza, G.M.1
  • 41
    • 58949100319 scopus 로고    scopus 로고
    • Targeted Herceptin-dextran iron oxide nanoparticles for noninvasive imaging of HER2/neu receptors using MRI
    • Chen TJ, Cheng TH, Chen CY, Hsu SC, Cheng TL, Liu GC, Wang YM,. Targeted Herceptin-dextran iron oxide nanoparticles for noninvasive imaging of HER2/neu receptors using MRI. J Biol Inorg Chem 2009; 14 (2): 253-260.
    • (2009) J Biol Inorg Chem , vol.14 , Issue.2 , pp. 253-260
    • Chen, T.J.1    Cheng, T.H.2    Chen, C.Y.3    Hsu, S.C.4    Cheng, T.L.5    Liu, G.C.6    Wang, Y.M.7
  • 42
    • 58149242593 scopus 로고    scopus 로고
    • Smart nanoprobes for ultrasensitive detection of breast cancer via magnetic resonance imaging
    • Lee J, Yang J, Seo SB, Ko HJ, Suh JS, Huh YM, Haam S,. Smart nanoprobes for ultrasensitive detection of breast cancer via magnetic resonance imaging. Nanotechnology 2008; 19 (48): 485101.
    • (2008) Nanotechnology , vol.19 , Issue.48 , pp. 485101
    • Lee, J.1    Yang, J.2    Seo, S.B.3    Ko, H.J.4    Suh, J.S.5    Huh, Y.M.6    Haam, S.7
  • 43
    • 69249220232 scopus 로고    scopus 로고
    • Anti-epidermal growth factor receptor (anti-EGFR) antibody conjugated fluorescent nanoparticles probe for breast cancer imaging
    • Hun X, Zhang Z,. Anti-epidermal growth factor receptor (anti-EGFR) antibody conjugated fluorescent nanoparticles probe for breast cancer imaging. Spectrochim Acta A Mol Biomol Spectrosc 2009; 74 (2): 410-414.
    • (2009) Spectrochim Acta A Mol Biomol Spectrosc , vol.74 , Issue.2 , pp. 410-414
    • Hun, X.1    Zhang, Z.2
  • 45
    • 78650356355 scopus 로고    scopus 로고
    • HER2/neu antibody conjugated poly(amino acid)-coated iron oxide nanoparticles for breast cancer MR imaging
    • Yang HM, Park CW, Woo MA, Kim MI, Jo YM, Park HG, Kim JD,. HER2/neu antibody conjugated poly(amino acid)-coated iron oxide nanoparticles for breast cancer MR imaging. Biomacromolecules 2010; 11 (11): 2866-2872.
    • (2010) Biomacromolecules , vol.11 , Issue.11 , pp. 2866-2872
    • Yang, H.M.1    Park, C.W.2    Woo, M.A.3    Kim, M.I.4    Jo, Y.M.5    Park, H.G.6    Kim, J.D.7
  • 47
    • 80051640793 scopus 로고    scopus 로고
    • Dextran-coated magnetic nanoclusters as highly sensitive contrast agents for magnetic resonance imaging of inflammatory macrophages
    • Lim E-K, Jang E, Kim B, Choi J, Lee K, Suh J-S, Huh Y-M, Haam S,. Dextran-coated magnetic nanoclusters as highly sensitive contrast agents for magnetic resonance imaging of inflammatory macrophages. J Mater Chem 2011; 21 (33): 12473.
    • (2011) J Mater Chem , vol.21 , Issue.33 , pp. 12473
    • Lim, E.-K.1    Jang, E.2    Kim, B.3    Choi, J.4    Lee, K.5    Suh, J.-S.6    Huh, Y.-M.7    Haam, S.8
  • 48
    • 80051822112 scopus 로고    scopus 로고
    • Hyaluronan-modified magnetic nanoclusters for detection of CD44-overexpressing breast cancer by MR imaging
    • Lim EK, Kim HO, Jang E, Park J, Lee K, Suh JS, Huh YM, Haam S,. Hyaluronan-modified magnetic nanoclusters for detection of CD44-overexpressing breast cancer by MR imaging. Biomaterials 2011; 32 (31): 7941-7950.
    • (2011) Biomaterials , vol.32 , Issue.31 , pp. 7941-7950
    • Lim, E.K.1    Kim, H.O.2    Jang, E.3    Park, J.4    Lee, K.5    Suh, J.S.6    Huh, Y.M.7    Haam, S.8
  • 49
    • 78651464824 scopus 로고    scopus 로고
    • Affibody-based nanoprobes for HER2-expressing cell and tumor imaging
    • Gao J, Chen K, Miao Z, Ren G, Chen X, Gambhir SS, Cheng Z,. Affibody-based nanoprobes for HER2-expressing cell and tumor imaging. Biomaterials 2011; 32 (8): 2141-2148.
    • (2011) Biomaterials , vol.32 , Issue.8 , pp. 2141-2148
    • Gao, J.1    Chen, K.2    Miao, Z.3    Ren, G.4    Chen, X.5    Gambhir, S.S.6    Cheng, Z.7
  • 52
    • 0032860385 scopus 로고    scopus 로고
    • Aptamers: An emerging class of molecules that rival antibodies in diagnostics
    • Jayasena SD,. Aptamers: An emerging class of molecules that rival antibodies in diagnostics. Clin Chem 1999; 45 (9): 1628-1650.
    • (1999) Clin Chem , vol.45 , Issue.9 , pp. 1628-1650
    • Jayasena, S.D.1
  • 53
    • 77954678126 scopus 로고    scopus 로고
    • Aptamer applications for targeted cancer therapy
    • Barbas AS, Mi J, Clary BM, White RR,. Aptamer applications for targeted cancer therapy. Future Oncol 2010; 6 (7): 1117-1126.
    • (2010) Future Oncol , vol.6 , Issue.7 , pp. 1117-1126
    • Barbas, A.S.1    Mi, J.2    Clary, B.M.3    White, R.R.4
  • 54
    • 80051500899 scopus 로고    scopus 로고
    • Image-guided prostate cancer therapy using aptamer-functionalized thermally cross-linked superparamagnetic iron oxide nanoparticles
    • Yu MK, Kim D, Lee IH, So JS, Jeong YY, Jon S,. Image-guided prostate cancer therapy using aptamer-functionalized thermally cross-linked superparamagnetic iron oxide nanoparticles. Small 2011; 7 (15): 2241-2249.
    • (2011) Small , vol.7 , Issue.15 , pp. 2241-2249
    • Yu, M.K.1    Kim, D.2    Lee, I.H.3    So, J.S.4    Jeong, Y.Y.5    Jon, S.6
  • 55
    • 80054972865 scopus 로고    scopus 로고
    • Smart multifunctional nanostructure for targeted cancer chemotherapy and magnetic resonance imaging
    • Chen T, Shukoor MI, Wang R, Zhao Z, Yuan Q, Bamrungsap S, Xiong X, Tan W,. Smart multifunctional nanostructure for targeted cancer chemotherapy and magnetic resonance imaging. ACS Nano 2011; 5 (10): 7866-7873.
    • (2011) ACS Nano , vol.5 , Issue.10 , pp. 7866-7873
    • Chen, T.1    Shukoor, M.I.2    Wang, R.3    Zhao, Z.4    Yuan, Q.5    Bamrungsap, S.6    Xiong, X.7    Tan, W.8
  • 57
    • 77950051368 scopus 로고    scopus 로고
    • Prostate cancer cell death produced by the co-delivery of Bcl-xL shRNA and doxorubicin using an aptamer-conjugated polyplex
    • Kim E, Jung Y, Choi H, Yang J, Suh JS, Huh YM, Kim K, Haam S,. Prostate cancer cell death produced by the co-delivery of Bcl-xL shRNA and doxorubicin using an aptamer-conjugated polyplex. Biomaterials 2010; 31 (16): 4592-4599.
    • (2010) Biomaterials , vol.31 , Issue.16 , pp. 4592-4599
    • Kim, E.1    Jung, Y.2    Choi, H.3    Yang, J.4    Suh, J.S.5    Huh, Y.M.6    Kim, K.7    Haam, S.8
  • 58
    • 80052277179 scopus 로고    scopus 로고
    • Aptamer-assembled nanomaterials for biosensing and biomedical applications
    • Kong RM, Zhang XB, Chen Z, Tan W,. Aptamer-assembled nanomaterials for biosensing and biomedical applications. Small 2011; 7: 2428-2436.
    • (2011) Small , vol.7 , pp. 2428-2436
    • Kong, R.M.1    Zhang, X.B.2    Chen, Z.3    Tan, W.4
  • 59
    • 80052169101 scopus 로고    scopus 로고
    • In vitro selection of RNA aptamer and specific targeting of ErbB2 in breast cancer cells
    • Kim MY, Jeong S,. In vitro selection of RNA aptamer and specific targeting of ErbB2 in breast cancer cells. Nucleic Acid Ther 2011; 21 (3): 173-178.
    • (2011) Nucleic Acid Ther , vol.21 , Issue.3 , pp. 173-178
    • Kim, M.Y.1    Jeong, S.2
  • 61
    • 80051817418 scopus 로고    scopus 로고
    • Aptamer-functionalized PEG-PLGA nanoparticles for enhanced anti-glioma drug delivery
    • Guo J, Gao X, Su L, Xia H, Gu G, Pang Z, Jiang X, Yao L, Chen J, Chen H,. Aptamer-functionalized PEG-PLGA nanoparticles for enhanced anti-glioma drug delivery. Biomaterials 2011; 32 (31): 8010-8020.
    • (2011) Biomaterials , vol.32 , Issue.31 , pp. 8010-8020
    • Guo, J.1    Gao, X.2    Su, L.3    Xia, H.4    Gu, G.5    Pang, Z.6    Jiang, X.7    Yao, L.8    Chen, J.9    Chen, H.10
  • 62
    • 78651419151 scopus 로고    scopus 로고
    • Dual-aptamer-based delivery vehicle of doxorubicin to both PSMA (+) and PSMA (-) prostate cancers
    • Min K, Jo H, Song K, Cho M, Chun YS, Jon S, Kim WJ, Ban C,. Dual-aptamer-based delivery vehicle of doxorubicin to both PSMA (+) and PSMA (-) prostate cancers. Biomaterials 2011; 32 (8): 2124-2132.
    • (2011) Biomaterials , vol.32 , Issue.8 , pp. 2124-2132
    • Min, K.1    Jo, H.2    Song, K.3    Cho, M.4    Chun, Y.S.5    Jon, S.6    Kim, W.J.7    Ban, C.8
  • 66
    • 79959926354 scopus 로고    scopus 로고
    • Sensitive angiogenesis imaging of orthotopic bladder tumors in mice using a selective magnetic resonance imaging contrast agent containing VEGF121/rGel
    • Cho EJ, Yang J, Mohamedali KA, Lim EK, Kim EJ, Farhangfar CJ, Suh JS, Haam S, Rosenblum MG, Huh YM,. Sensitive angiogenesis imaging of orthotopic bladder tumors in mice using a selective magnetic resonance imaging contrast agent containing VEGF121/rGel. Invest Radiol 2011; 46 (7): 441-449.
    • (2011) Invest Radiol , vol.46 , Issue.7 , pp. 441-449
    • Cho, E.J.1    Yang, J.2    Mohamedali, K.A.3    Lim, E.K.4    Kim, E.J.5    Farhangfar, C.J.6    Suh, J.S.7    Haam, S.8    Rosenblum, M.G.9    Huh, Y.M.10
  • 67
    • 79957815663 scopus 로고    scopus 로고
    • PH-triggered drug-releasing magnetic nanoparticles for cancer therapy guided by molecular imaging by MRI
    • Lim EK, Huh YM, Yang J, Lee K, Suh JS, Haam S,. pH-triggered drug-releasing magnetic nanoparticles for cancer therapy guided by molecular imaging by MRI. Adv Mater 2011; 23 (21): 2436-2442.
    • (2011) Adv Mater , vol.23 , Issue.21 , pp. 2436-2442
    • Lim, E.K.1    Huh, Y.M.2    Yang, J.3    Lee, K.4    Suh, J.S.5    Haam, S.6
  • 68
    • 36749044732 scopus 로고    scopus 로고
    • Multifunctional magneto-polymeric nanohybrids for targeted detection and synergistic therapeutic effects on breast cancer
    • Yang J, Lee CH, Ko HJ, Suh JS, Yoon HG, Lee K, Huh YM, Haam S,. Multifunctional magneto-polymeric nanohybrids for targeted detection and synergistic therapeutic effects on breast cancer. Angew Chem Int Ed 2007; 46 (46): 8836-8839.
    • (2007) Angew Chem Int Ed , vol.46 , Issue.46 , pp. 8836-8839
    • Yang, J.1    Lee, C.H.2    Ko, H.J.3    Suh, J.S.4    Yoon, H.G.5    Lee, K.6    Huh, Y.M.7    Haam, S.8
  • 70
    • 72049089817 scopus 로고    scopus 로고
    • Smart drug-loaded polymer gold nanoshells for systemic and localized therapy of human epithelial cancer
    • Yang J, Lee J, Kang J, Oh SJ, Ko H-J, Son J-H, Lee K, Suh J-S, Huh Y-M, Haam S,. Smart drug-loaded polymer gold nanoshells for systemic and localized therapy of human epithelial cancer. Adv Mater 2009; 21 (43): 4339-4342.
    • (2009) Adv Mater , vol.21 , Issue.43 , pp. 4339-4342
    • Yang, J.1    Lee, J.2    Kang, J.3    Oh, S.J.4    Ko, H.-J.5    Son, J.-H.6    Lee, K.7    Suh, J.-S.8    Huh, Y.-M.9    Haam, S.10
  • 71
    • 79952833266 scopus 로고    scopus 로고
    • Specific near-IR absorption imaging of glioblastomas using integrin-targeting gold nanorods
    • Choi J, Yang J, Park J, Kim E, Suh J-S, Huh Y-M, Haam S,. Specific near-IR absorption imaging of glioblastomas using integrin-targeting gold nanorods. Adv Funct Mater 2011; 21 (6): 1082-1088.
    • (2011) Adv Funct Mater , vol.21 , Issue.6 , pp. 1082-1088
    • Choi, J.1    Yang, J.2    Park, J.3    Kim, E.4    Suh, J.-S.5    Huh, Y.-M.6    Haam, S.7
  • 72
    • 34547137386 scopus 로고    scopus 로고
    • Cyclic Arg-Gly-Asp peptide-labeled liposomes for targeting drug therapy of hepatic fibrosis in rats
    • Du SL, Pan H, Lu WY, Wang J, Wu J, Wang JY,. Cyclic Arg-Gly-Asp peptide-labeled liposomes for targeting drug therapy of hepatic fibrosis in rats. J Pharmacol Exp Ther 2007; 322 (2): 560-568.
    • (2007) J Pharmacol Exp Ther , vol.322 , Issue.2 , pp. 560-568
    • Du, S.L.1    Pan, H.2    Lu, W.Y.3    Wang, J.4    Wu, J.5    Wang, J.Y.6
  • 73
    • 0344256437 scopus 로고    scopus 로고
    • The RGD story: A personal account
    • Ruoslahti E,. The RGD story: A personal account. Matrix Biol 2003; 22 (6): 459-465.
    • (2003) Matrix Biol , vol.22 , Issue.6 , pp. 459-465
    • Ruoslahti, E.1
  • 74
    • 0025991563 scopus 로고
    • Vascular endothelial cell growth factor (VEGF) produced by A-431 human epidermoid carcinoma cells and identification of VEGF membrane binding sites
    • Myoken Y, Kayada Y, Okamoto T, Kan M, Sato GH, Sato JD,. Vascular endothelial cell growth factor (VEGF) produced by A-431 human epidermoid carcinoma cells and identification of VEGF membrane binding sites. Proc Natl Acad Sci USA 1991; 88 (13): 5819-5823.
    • (1991) Proc Natl Acad Sci USA , vol.88 , Issue.13 , pp. 5819-5823
    • Myoken, Y.1    Kayada, Y.2    Okamoto, T.3    Kan, M.4    Sato, G.H.5    Sato, J.D.6
  • 75
    • 84864258079 scopus 로고    scopus 로고
    • The effect of nanoparticle size, shape, and surface chemistry on biological systems
    • Albanese A, Tang PS, Chan WC,. The effect of nanoparticle size, shape, and surface chemistry on biological systems. Annu Rev Biomed Eng. 2012; 14: 1-16.
    • (2012) Annu Rev Biomed Eng. , vol.14 , pp. 1-16
    • Albanese, A.1    Tang, P.S.2    Chan, W.C.3
  • 77
    • 51049104302 scopus 로고    scopus 로고
    • Pharmacokinetics and biodistribution of nanoparticles
    • Li S-D, Huang L,. Pharmacokinetics and biodistribution of nanoparticles. Mol Pharm 2008; 5 (4): 496-504.
    • (2008) Mol Pharm , vol.5 , Issue.4 , pp. 496-504
    • Li, S.-D.1    Huang, L.2


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