High performance and reversible ionic polypeptide hydrogel based on charge-driven assembly for biomedical applications

Acta Biomaterialia

Volumn 11, Issue 1, 2015, Pages 183-190

  Cui, Haitao ^a,b   Zhuang, Xiuli ^a   He, Chaoliang ^a   Wei, Yen ^c   Chen, Xuesi ^a  

^a CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c TSINGHUA UNIVERSITY   (China)

Author keywords

Charge driven; Injectable hydrogel; Ionic polypeptides; Reversible response

Indexed keywords

AMINO ACIDS; BIOCOMPATIBILITY; ETHYLENE GLYCOL; MEDICAL APPLICATIONS; PHASE LOCKED LOOPS; POLYELECTROLYTES; POLYETHYLENE GLYCOLS; POLYOLS; POLYPEPTIDES;

BIOMEDICAL APPLICATIONS; CHARGE-DRIVEN; INJECTABLE HYDROGELS; IONIC POLYPEPTIDE; PERFORMANCE; POLY-(L-GLUTAMIC ACID); POLY-L-GLUTAMIC ACIDS; POLY-L-LYSINE; REVERSIBLE RESPONSE; TRIBLOCKS;

HYDROGELS;

BIOMEDICAL AND DENTAL MATERIALS; COPOLYMER; EOSIN; HEMATOXYLIN; POLY(LEVO GLUTAMIC ACID) BLOCK POLY(ETHYLENE GLYCOL) BLOCK POLY(LEVO GLUTAMIC ACID); POLY(LEVO LYSINE) BLOCK POLY(ETHYLENE GLYCOL) BLOCK POLY(LEVO LYSINE); POLYELECTROLYTE; POLYPEPTIDE; UNCLASSIFIED DRUG; HYDROGEL; MACROGOL DERIVATIVE; POLYGLUTAMIC ACID; POLYLYSINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOCOMPATIBILITY; BIODEGRADABILITY; BIOMEDICAL ENGINEERING; CELL ENCAPSULATION; CELL VIABILITY; CONJUGATE; CONTROLLED STUDY; CROSS LINKING; HYDROGEL; IN VITRO STUDY; IN VIVO STUDY; IONIC STRENGTH; MECHANICS; MOUSE; NONHUMAN; PEPTIDE SYNTHESIS; PHASE SEPARATION; PHYSICAL PARAMETERS; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN SECRETION; RAT; STAINING; ANIMAL; CELL LINE; CHEMISTRY; MATERIALS TESTING; PHARMACOLOGY; SPRAGUE DAWLEY RAT; SYNTHESIS;

RATTUS;

ANIMALS; CELL LINE; HYDROGELS; MATERIALS TESTING; MICE; POLYETHYLENE GLYCOLS; POLYGLUTAMIC ACID; POLYLYSINE; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84925210055     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2014.09.017     Document Type: Article

References (29)

1. Ko DY, Shinde UP, Yeon B, Jeong B. Recent progress of in situ formed gels for biomedical applications. Prog Polym Sci 2013;38:672-701.
2. Drury JL, Mooney DJ. Hydrogels for tissue engineering: scaffold design variables and applications. Biomaterials 2003;24:4337-51.
3. Peppas NA, Hilt JZ, Khademhosseini A, Langer R. Hydrogels in biology and medicine: from molecular principles to bionanotechnology. Adv Mater 2006;18:1345-60.
4. Gao XY, He CL, Zhuang XL, Zhao CW, Xiao CS, Chen XS. Synthesis and swelling behavior of degradable pH-sensitive hydrogels composed of poly(L-glutamic acid) and poly(acrylic acid). Acta Polym Sin 2011;11:883-8.
5. Xiao CS, Tian HY, Zhuang XL, Chen XS, Jing XB. Recent developments in intelligent biomedical polymers. Sci China Ser B Chem 2009;52:117-30.
6. Patenaude M, Hoare T. Injectable, mixed natural-synthetic polymer hydrogels with modular properties. Biomacromolecules 2012;13:369-78.
7. Li Y, Rodrigues J, Tomas H. Injectable and biodegradable hydrogels: gelation, biodegradation and biomedical applications. Chem Soc Rev 2012;41:2193-221.
8. Tsitsilianis C. Responsive reversible hydrogels from associative "smart"macromolecules. Soft Matter 2010;6:2372-88.
9. Van Tomme SR, Storm G, Hennink WE. In situ gelling hydrogels for pharmaceutical and biomedical applications. Int J Pharm 2008;355:1-18.
10. Cheng YL, He CL, Xiao CS, Ding JX, Zhuang XL, Huang YB, et al. Decisive role of hydrophobic side groups of polypeptides in thermosensitive gelation. Biomacromolecules 2012;13:2053-9.
11. Cui HT, Shao J, Wang Y, Zhang PB, Chen XS, Wei Y. PLA-PEG-PLA and its electroactive tetraaniline copolymer as multi-interactive injectable hydrogels for tissue engineering. Biomacromolecules 2013;14:1904-12.
12. Moura MJ, Faneca H, Pedroso de Lima MC, Gil MH, Figueiredo MM. In situ forming chitosan hydrogels prepared via ionic/covalent co-cross-linking. Biomacromolecules 2011;12:3275-84.
13. Matson JB, Stupp SI. Self-assembling peptide scaffolds for regenerative medicine. Chem Commun 2012;48:26-33.
14. Bajomo M, Robb I, Steinke JHG, Bismarck A. Fully reversible pH-triggered network formation of amphoteric polyelectrolyte hydrogels. Adv Funct Mater 2011;21:172-6.
15. Lemmers M, Sprakel J, Voets IK, van der Gucht J, Cohen Stuart MA. Multiresponsive reversible gels based on charge-driven assembly. Angew Chem Int Ed Engl 2010;49:708-11.
16. Hunt JN, Feldman KE, Lynd NA, Deek J, Campos LM, Spruell JM, et al. Tunable, high modulus hydrogels driven by ionic coacervation. Adv Mater 2011;23:2327-31.
17. Krogstad DV, Lynd NA, Choi S, Spruell JM, Hawker CJ, Kramer EJ, et al. Effects of polymer and salt concentration on the structure and properties of triblock copolymer coacervate hydrogels. Macromolecules 2013;46:1512-8.
18. Voets IK, Burgh S, Farago B, Fokkink R, Kovacevic D, Hellweg T, et al. Electrostatically driven coassembly of a diblock copolymer and an oppositely charged homopolymer in aqueous solutions. Macromolecules 2007;40:8476-82.
19. Priftis D, Tirrell M. Phase behaviour and complex coacervation of aqueous polypeptide solutions. Soft Matter 2012;8:9396-405.
20. Priftis D, Laugel N, Tirrell M. Thermodynamic characterization of polypeptide complex coacervation. Langmuir 2012;28:15947-57.
21. Thompson MS, Vadala TP, Vadala ML, Lin Y, Riffl JS. Synthesis and applications of heterobifunctional poly(ethylene oxide) oligomers. Polymer 2008;49:345-73.
22. Song WT, Li MQ, Tang ZH, Li QS, Yang Y, Liu HY, et al. Methoxypoly(ethylene glycol)-block-poly-(L-glutamic acid)-loaded cisplatin and a combination with iRGD for the treatment of non-small-cell lung cancers. Macromol Biosci 2012;12:1514-23.
23. Ding JX, Chen JJ, Li D, Xiao CS, Zhang JC, He CL, et al. Biocompatible reduction-responsive polypeptide micelles as nanocarriers for enhanced chemotherapy efficacy in vitro. J Mater Chem B 2013;1:69-81.
24. Cheng YL, He CL, Xiao CS, Ding JX, Cui HT, Zhuang XL, et al. Versatile biofunctionalization of polypeptide-based thermosensitive hydrogels via click chemistry. Biomacromolecules 2013;14:468-75.
25. Moon HJ, Choi BG, Park MH, Joo MK, Jeong B. Enzymatically degradable thermogelling poly(alanine-co-leucine)-poloxamer-poly(alanine-co-leucine). Biomacromolecules 2011;12:1234-42.
26. Cheng YL, He CL, Ding JX, Xiao CS, Zhuang XL, Chen XS. Thermosensitive hydrogels based on polypeptides for localized and sustained delivery of anticancer drugs. Biomaterials 2013;34:10338-47.
27. Li JG, Wang T, Wu DL, Zhang XQ, Yan JT, Du S, et al. Stimuli-responsive zwitterionic block copolypeptides: poly(N-isopropylacrylamide)-blockpoly(lysine-co-glutamic acid). Biomacromolecules 2008;9:2670-6.
28. Huang Y, Tang ZH, Zhang XF, Yu HY, Sun H, Pang X, et al. PH-Triggered charge-reversal polypeptide nanoparticles for cisplatin delivery: preparation and in vitro evaluation. Biomacromolecules 2013;14:2023-32.
29. Rinaudo M, Domard A. Circular dichroism studies on α-L-glutamic acid oligomers in solution. J Am Chem Soc 1976;98:6360-4.