Activatable aptamer probe for contrast-enhanced in vivo cancer imaging based on cell membrane protein-triggered conformation alteration

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 10, 2011, Pages 3900-3905

  Shi, Hui ^a   He, Xiaoxiao ^a   Wang, Kemin ^a   Wu, Xu ^a   Ye, Xiaosheng ^a   Guo, Qiuping ^a   Tan, Weihong ^a   Qing, Zhihe ^a   Yang, Xiaohai ^a   Zhou, Bing ^a  

^a HUNAN UNIVERSITY   (China)

Author keywords

Activatable fluorescent molecular imaging; Cancer detection; Cell surface protein; In vivo imaging; Switchable aptamer probe

Indexed keywords

APTAMER; CELL MEMBRANE PROTEIN;

ACTIVATABLE APTAMER PROBE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL; CANCER DIAGNOSIS; CELL ACTIVATION; CELL COUNT; CONTRAST ENHANCEMENT; DNA SEQUENCE; FLOW CYTOMETRY; FLUORESCENCE IMAGING; HUMAN; HUMAN CELL; IN VIVO STUDY; MALE; MOLECULAR PROBE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN CONFORMATION; SIGNAL TRANSDUCTION;

APTAMERS, NUCLEOTIDE; BASE SEQUENCE; CELL LINE; DNA PROBES; FLOW CYTOMETRY; HUMANS; MEMBRANE PROTEINS; NEOPLASMS; PROTEIN CONFORMATION; SPECTROMETRY, FLUORESCENCE;

MUS;

EID: 79952775709     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1016197108     Document Type: Article

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