Selective uptake and imaging of aptamer- and antibody-conjugated hollow nanospheres targeted to epidermal growth factor receptors overexpressed in head and neck cancer

ACS Nano

Volumn 8, Issue 5, 2014, Pages 4530-4538

  Melancon, Marites Pasuelo ^a   Zhou, Min ^a   Zhang, Rui ^a   Xiong, Chiyi ^a   Allen, Peter ^b   Wen, Xiaoxia ^a   Huang, Qian ^a   Wallace, Michael ^a   Myers, Jeffrey N ^a   Stafford, R Jason ^a   Liang, Dong ^c   Ellington, Andrew D ^b   Li, Chun ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^c TEXAS SOUTHERN UNIVERSITY   (United States)

Author keywords

aptamer; biodistribution; epidermal growth factor receptor; head and neck cancer; hollow gold nanospheres; SPECT CT

Indexed keywords

BINDING ENERGY; DISEASES; DNA; GOLD; GOLD COATINGS; NANOSPHERES; TUMORS;

APTAMERS; BIODISTRIBUTIONS; EPIDERMAL GROWTH FACTOR RECEPTORS; GOLD NANOSPHERES; HEAD-AND-NECK CANCER; SPECT/CT;

ANTIBODIES;

ANTIBODY; EPIDERMAL GROWTH FACTOR RECEPTOR; GOLD; LIGAND; MACROGOL DERIVATIVE; METAL NANOPARTICLE; NANOSPHERE; PROTEIN BINDING; SINGLE STRANDED DNA;

ANIMAL; AREA UNDER THE CURVE; CANCER TRANSPLANTATION; CHEMISTRY; COMPUTER ASSISTED TOMOGRAPHY; HEAD AND NECK NEOPLASMS; HUMAN; MALE; METABOLISM; MOUSE; NANOTECHNOLOGY; NUDE MOUSE; PROCEDURES; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SQUAMOUS CELL CARCINOMA;

ANIMALS; ANTIBODIES; AREA UNDER CURVE; CARCINOMA, SQUAMOUS CELL; DNA, SINGLE-STRANDED; GOLD; HEAD AND NECK NEOPLASMS; HUMANS; LIGANDS; MALE; METAL NANOPARTICLES; MICE; MICE, NUDE; NANOSPHERES; NANOTECHNOLOGY; NEOPLASM TRANSPLANTATION; POLYETHYLENE GLYCOLS; PROTEIN BINDING; RECEPTOR, EPIDERMAL GROWTH FACTOR; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84901684196     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn406632u     Document Type: Article

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