Somatic mosaicism in the human genome

Genes

Volumn 5, Issue 4, 2014, Pages 1064-1094

  Freed, Donald ^a,b   Stevens, Eric L ^a,b,c   Pevsner, Jonathan ^a,b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b KENNEDY KRIEGER INSTITUTE   (United States)

^c CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

Aging; Complex disease; Germline; Mosaicism; Mutation; Neurodegeneration; Retrotransposition; Somatic

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; RAF PROTEIN; RAS PROTEIN;

AGING; AKT GENE; CANCER RISK; CYTOGENETICS; DEGENERATIVE DISEASE; DEVELOPMENTAL STAGE; GENE; GENE FREQUENCY; GENE FUNCTION; GENETIC ASSOCIATION; GENETIC VARIABILITY; GNAQ GENE; HUMAN; HUMAN GENOME; INTRACELLULAR SIGNALING; MEK GENE; MONOGENIC DISORDER; MOSAICISM; NEOPLASM; NF1 GENE; NONHUMAN; ONCOGENE RAS; PHENOTYPE; PIK3CA GENE; PTEN GENE; RAF GENE; REVIEW; SECOND GENERATION SEQUENCING; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; SOMATIC MOSAICISM; SOMATIC MUTATION; SOMATIC VARIATION; TSC1 GENE; TSC2 GENE;

EID: 84938879480     PISSN: None     EISSN: 20734425     Source Type: Journal    
DOI: 10.3390/genes5041064     Document Type: Review

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