Chromosome instability is common in human cleavage-stage embryos

Nature Medicine

Volumn 15, Issue 5, 2009, Pages 577-583

  Vanneste, Evelyne ^a   Voet, Thierry ^a   Le Caignec, Cédric ^a,b,c   Ampe, Michèle ^a   Konings, Peter ^a   Melotte, Cindy ^a   Debrock, Sophie ^a   Amyere, Mustapha ^d   Vikkula, Miikka ^d   Schuit, Frans ^e   Fryns, Jean Pierre ^a   Verbeke, Geert ^a   D'Hooghe, Thomas ^a   Moreau, Yves ^a   Vermeesch, Joris R ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b NANTES UNIVERSITY HOSPITAL   (France)

^c L INSTITUT DU THORAX   (France)

^d DE DUVE INSTITUTE   (Belgium)

^e UNIVERSITY HOSPITALS LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ANEUPLOIDY; ARTICLE; BLASTOMERE; CHROMOSOMAL INSTABILITY; CHROMOSOME DELETION; CHROMOSOME DISORDER; CHROMOSOME DUPLICATION; EMBRYO; EMBRYO DEVELOPMENT; HETEROZYGOSITY LOSS; HUMAN; MONOSOMY X; MOSAICISM; OOCYTE CLEAVAGE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; TRISOMY 21; UNIPARENTAL DISOMY;

ADULT; ANEUPLOIDY; BLASTOMERES; CHROMOSOMAL INSTABILITY; EMBRYO, MAMMALIAN; FEMALE; FERTILIZATION IN VITRO; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; LOSS OF HETEROZYGOSITY; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYMORPHISM, SINGLE NUCLEOTIDE; PREGNANCY;

EID: 66749169417     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.1924     Document Type: Article

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