-
1
-
-
34548638261
-
Structure and mechanism of helicases and nucleic acid translocases
-
Singleton M.R., Dillingham M.S., Wigley D.B. Structure and mechanism of helicases and nucleic acid translocases. Annu Rev Biochem 2007, 76(1):23-50.
-
(2007)
Annu Rev Biochem
, vol.76
, Issue.1
, pp. 23-50
-
-
Singleton, M.R.1
Dillingham, M.S.2
Wigley, D.B.3
-
2
-
-
77953024275
-
Probing the structural basis of RecQ helicase function
-
Vindigni A., Marino F., Gileadi O. Probing the structural basis of RecQ helicase function. Biophys Chem 2010, 149:67-77.
-
(2010)
Biophys Chem
, vol.149
, pp. 67-77
-
-
Vindigni, A.1
Marino, F.2
Gileadi, O.3
-
3
-
-
84944972302
-
Congenital telangiectatic erythema resembling lupus erythematosus in dwarfs
-
Bloom D. Congenital telangiectatic erythema resembling lupus erythematosus in dwarfs. Am J Dis Child 1954, 88:754-758.
-
(1954)
Am J Dis Child
, vol.88
, pp. 754-758
-
-
Bloom, D.1
-
4
-
-
0027331383
-
Bloom syndrome: a Mendelian prototype of somatic mutational disease
-
German J. Bloom syndrome: a Mendelian prototype of somatic mutational disease. Medicine 1993, 72:393-406.
-
(1993)
Medicine
, vol.72
, pp. 393-406
-
-
German, J.1
-
5
-
-
3042945232
-
Bloom's syndrome. VIII. Review of clinical and genetic aspects
-
Raven Press, New York, R.M. Goodman, A.G. Motulsky (Eds.)
-
German J. Bloom's syndrome. VIII. Review of clinical and genetic aspects. Genetic diseases among Askenazi jews 1979, 121-139. Raven Press, New York. R.M. Goodman, A.G. Motulsky (Eds.).
-
(1979)
Genetic diseases among Askenazi jews
, pp. 121-139
-
-
German, J.1
-
6
-
-
0031052108
-
Bloom's syndrome: XX. The first 100 cancers
-
German J. Bloom's syndrome: XX. The first 100 cancers. Cytogenet Cell Genet 1997, 93:100-106.
-
(1997)
Cytogenet Cell Genet
, vol.93
, pp. 100-106
-
-
German, J.1
-
7
-
-
0013907774
-
Werner's syndrome: a review of its symptomatology, natural history, pathologic features, genetics and relationship to the natural aging process
-
Epstein C.J., Martin G.M., Schultz A.L., Motulsky A.G. Werner's syndrome: a review of its symptomatology, natural history, pathologic features, genetics and relationship to the natural aging process. Medicine 1966, 45:177-221.
-
(1966)
Medicine
, vol.45
, pp. 177-221
-
-
Epstein, C.J.1
Martin, G.M.2
Schultz, A.L.3
Motulsky, A.G.4
-
8
-
-
0030691121
-
Hierarchical deterioration of body systems in Werner's syndrome: implications for normal ageing
-
Goto M. Hierarchical deterioration of body systems in Werner's syndrome: implications for normal ageing. Mech Ageing Dev 1997, 98:239-254.
-
(1997)
Mech Ageing Dev
, vol.98
, pp. 239-254
-
-
Goto, M.1
-
9
-
-
78649475037
-
Werner syndrome as a model of human aging
-
Elsevier Academic Press, Amsterdam, P.M. Conn (Ed.)
-
Monnat R.J. Werner syndrome as a model of human aging. Handbook of models for human aging 2006, 961-976. Elsevier Academic Press, Amsterdam. P.M. Conn (Ed.).
-
(2006)
Handbook of models for human aging
, pp. 961-976
-
-
Monnat, R.J.1
-
10
-
-
78649471545
-
-
On cataract in conjunction with scleroderma [Hoehn H, Trans.]. In: Salk D, Fujiwara Y, Martin GM, editors. Werner's syndrome and human aging. New York: Plenum Press
-
Werner O. On cataract in conjunction with scleroderma [Hoehn H, Trans.]. In: Salk D, Fujiwara Y, Martin GM, editors. Werner's syndrome and human aging. New York: Plenum Press; 1985. pp. 1-14.
-
(1985)
, pp. 1-14
-
-
Werner, O.1
-
11
-
-
0021171248
-
Werner's sydrome: an underdiagnosed disorder resembling premature aging
-
Tollefsbol T.O., Cohen H.J. Werner's sydrome: an underdiagnosed disorder resembling premature aging. Age 1984, 7:75-88.
-
(1984)
Age
, vol.7
, pp. 75-88
-
-
Tollefsbol, T.O.1
Cohen, H.J.2
-
12
-
-
33846289198
-
Excess of rare cancers in Werner syndrome (adult progeria)
-
Goto M., Miller R.W., Ishikawa Y., Sugano H. Excess of rare cancers in Werner syndrome (adult progeria). Cancer Epidemiol Biomarkers Prev 1996, 5:239-246.
-
(1996)
Cancer Epidemiol Biomarkers Prev
, vol.5
, pp. 239-246
-
-
Goto, M.1
Miller, R.W.2
Ishikawa, Y.3
Sugano, H.4
-
13
-
-
0034798464
-
Cancer pathogenesis in the human RecQ helicase deficiency syndromes
-
Japan Scientific Societies Press, Tokyo, Japan, M. Goto, R.W. Miller (Eds.)
-
Monnat R.J. Cancer pathogenesis in the human RecQ helicase deficiency syndromes. From premature gray hair to helicase - Werner syndrome: implications for aging and cancer 2001, 83-94. Japan Scientific Societies Press, Tokyo, Japan. M. Goto, R.W. Miller (Eds.).
-
(2001)
From premature gray hair to helicase - Werner syndrome: implications for aging and cancer
, pp. 83-94
-
-
Monnat, R.J.1
-
15
-
-
33744990645
-
The spectrum of WRN mutations in Werner syndrome patients
-
Huang S., Lee L., Hanson N.B., et al. The spectrum of WRN mutations in Werner syndrome patients. Human Mutat 2006, 27:558-567.
-
(2006)
Human Mutat
, vol.27
, pp. 558-567
-
-
Huang, S.1
Lee, L.2
Hanson, N.B.3
-
16
-
-
51249195723
-
Ueber cataracten in verbindung mit einer eigentümlichen hautdegenera-tion
-
Rothmund A. Ueber cataracten in verbindung mit einer eigentümlichen hautdegenera-tion. Arch Klin Exp Ophtal 1868, 14(1):159-182.
-
(1868)
Arch Klin Exp Ophtal
, vol.14
, Issue.1
, pp. 159-182
-
-
Rothmund, A.1
-
17
-
-
84980087875
-
Poikiloderma congenitale
-
Thomson M.S. Poikiloderma congenitale. Br J Dermatol 1936, 48:221-234.
-
(1936)
Br J Dermatol
, vol.48
, pp. 221-234
-
-
Thomson, M.S.1
-
18
-
-
3242804840
-
Rothmund's syndrome-Thomson's syndrome: congenital poikiloderma with and without juvenile cataracts. A review of the literature, report of a case, and discussion of the relationship of the two syndromes
-
Taylor W.B. Rothmund's syndrome-Thomson's syndrome: congenital poikiloderma with and without juvenile cataracts. A review of the literature, report of a case, and discussion of the relationship of the two syndromes. AMA Arch Dermatol 1957, 75:236-244.
-
(1957)
AMA Arch Dermatol
, vol.75
, pp. 236-244
-
-
Taylor, W.B.1
-
19
-
-
0035934019
-
Clinical manifestations in a cohort of 41 Rothmund-Thomson syndrome patients
-
Wang L.L., Levy M.L., Lewis R.A., et al. Clinical manifestations in a cohort of 41 Rothmund-Thomson syndrome patients. Am J Hum Genet 2001, 102:11-17.
-
(2001)
Am J Hum Genet
, vol.102
, pp. 11-17
-
-
Wang, L.L.1
Levy, M.L.2
Lewis, R.A.3
-
21
-
-
0242609126
-
Molecular defect of RAPADILINO syndrome expands the phenotype spectrum of RECQL diseases
-
Siitonen H.A., Kopra O., Kaariainen H., et al. Molecular defect of RAPADILINO syndrome expands the phenotype spectrum of RECQL diseases. Hum Mol Genet 2003, 12(21):2837-2844.
-
(2003)
Hum Mol Genet
, vol.12
, Issue.21
, pp. 2837-2844
-
-
Siitonen, H.A.1
Kopra, O.2
Kaariainen, H.3
-
22
-
-
32944476196
-
Revisiting the craniosynostosis-radial ray hypoplasia association: Baller-Gerold syndrome caused by mutations in the RECQL4 gene
-
Van Maldergem L., Siitonen H.A., Jalkh N., et al. Revisiting the craniosynostosis-radial ray hypoplasia association: Baller-Gerold syndrome caused by mutations in the RECQL4 gene. J Med Genet 2006, 43:148-152.
-
(2006)
J Med Genet
, vol.43
, pp. 148-152
-
-
Van Maldergem, L.1
Siitonen, H.A.2
Jalkh, N.3
-
23
-
-
0038288850
-
Association between osteosarcoma and deleterious mutations in the RECQL4 gene in Rothmund-Thomson syndrome
-
Wang L.L., Gannavarapu A., Kozinetz C.A., et al. Association between osteosarcoma and deleterious mutations in the RECQL4 gene in Rothmund-Thomson syndrome. J Natl Cancer Inst 2003, 95:669-674.
-
(2003)
J Natl Cancer Inst
, vol.95
, pp. 669-674
-
-
Wang, L.L.1
Gannavarapu, A.2
Kozinetz, C.A.3
-
24
-
-
69249209608
-
RecQ helicases: multifunctional genome caretakers
-
Chu W.K., Hickson I.D. RecQ helicases: multifunctional genome caretakers. Nat Rev Cancer 2009, 9(9):644-654.
-
(2009)
Nat Rev Cancer
, vol.9
, Issue.9
, pp. 644-654
-
-
Chu, W.K.1
Hickson, I.D.2
-
25
-
-
0028785586
-
The Bloom's syndrome gene product is homologous to RecQ helicases
-
Ellis N.A., Groden J., Ye T.-Z., et al. The Bloom's syndrome gene product is homologous to RecQ helicases. Cell 1995, 83:655-666.
-
(1995)
Cell
, vol.83
, pp. 655-666
-
-
Ellis, N.A.1
Groden, J.2
Ye, T.-Z.3
-
26
-
-
15844409553
-
Positional cloning of the Werner's syndrome gene
-
Yu C.-E., Oshima J., Fu Y.-H., et al. Positional cloning of the Werner's syndrome gene. Science 1996, 272:258-262.
-
(1996)
Science
, vol.272
, pp. 258-262
-
-
Yu, C.-E.1
Oshima, J.2
Fu, Y.-H.3
-
27
-
-
0026748240
-
Werner syndrome: molecular genetics and mechanistic hypotheses
-
Monnat R.J. Werner syndrome: molecular genetics and mechanistic hypotheses. Exp Gerontol 1992, 27:447-453.
-
(1992)
Exp Gerontol
, vol.27
, pp. 447-453
-
-
Monnat, R.J.1
-
28
-
-
0032939991
-
Mutations in RECQ4L cause a subset of cases of Rothmund-Thomson syndrome
-
Kitao S., Shimamoto A., Goto M., et al. Mutations in RECQ4L cause a subset of cases of Rothmund-Thomson syndrome. Nat Genet 1999, 22:82-84.
-
(1999)
Nat Genet
, vol.22
, pp. 82-84
-
-
Kitao, S.1
Shimamoto, A.2
Goto, M.3
-
29
-
-
0032535661
-
Cloning of two new human helicase genes of the RecQ family: biological significance of multiple species in higher eukaryotes
-
Kitao S., Ohsugi I., Ichikawa K., et al. Cloning of two new human helicase genes of the RecQ family: biological significance of multiple species in higher eukaryotes. Genomics 1998, 54:443-452.
-
(1998)
Genomics
, vol.54
, pp. 443-452
-
-
Kitao, S.1
Ohsugi, I.2
Ichikawa, K.3
-
30
-
-
0027942415
-
Cloning and characterization of RecQL, a potential human homologue of the Escherichia coli DNA helicase RecQ
-
Puranam K.L., Blackshear P.J. Cloning and characterization of RecQL, a potential human homologue of the Escherichia coli DNA helicase RecQ. J Biol Chem 1994, 269:29838-29845.
-
(1994)
J Biol Chem
, vol.269
, pp. 29838-29845
-
-
Puranam, K.L.1
Blackshear, P.J.2
-
31
-
-
0028061993
-
Molecular cloning of cDNA encoding human DNA helicase Q1 which has homology to Escherichia coli RecQ helicase and localization of the gene at chromosome 12p12
-
Seki M., Miyazawa H., Tada S., et al. Molecular cloning of cDNA encoding human DNA helicase Q1 which has homology to Escherichia coli RecQ helicase and localization of the gene at chromosome 12p12. Nucleic Acids Res 1994, 22:4566-4573.
-
(1994)
Nucleic Acids Res
, vol.22
, pp. 4566-4573
-
-
Seki, M.1
Miyazawa, H.2
Tada, S.3
-
32
-
-
33847228012
-
RECQL, a Member of the RecQ Family of DNA helicases, suppresses chromosomal instability
-
Sharma S., Stumpo D.J., Balajee A.S., et al. RECQL, a Member of the RecQ Family of DNA helicases, suppresses chromosomal instability. Mol Cell Biol 2007, 27(5):1784-1794.
-
(2007)
Mol Cell Biol
, vol.27
, Issue.5
, pp. 1784-1794
-
-
Sharma, S.1
Stumpo, D.J.2
Balajee, A.S.3
-
33
-
-
76749143650
-
RECQL5 helicase: connections to DNA recombination and RNA polymerase II transcription
-
Aygün O., Svejstrup J.Q. RECQL5 helicase: connections to DNA recombination and RNA polymerase II transcription. DNA Repair 2010, 9(3):345-353.
-
(2010)
DNA Repair
, vol.9
, Issue.3
, pp. 345-353
-
-
Aygün, O.1
Svejstrup, J.Q.2
-
34
-
-
76749101923
-
Distinct roles of RECQ1 in the maintenance of genomic stability
-
Wu Y., Brosh J. Distinct roles of RECQ1 in the maintenance of genomic stability. DNA Repair 2010, 9(3):315-324.
-
(2010)
DNA Repair
, vol.9
, Issue.3
, pp. 315-324
-
-
Wu, Y.1
Brosh, J.2
-
35
-
-
34247562576
-
Syndrome-causing mutations of the BLM gene in persons in the Bloom syndrome registry
-
German J., Sanz M.M., Ciocci S., Ye T.-Z., Ellis N.A. Syndrome-causing mutations of the BLM gene in persons in the Bloom syndrome registry. Human Mutat 2007, 28:743-753.
-
(2007)
Human Mutat
, vol.28
, pp. 743-753
-
-
German, J.1
Sanz, M.M.2
Ciocci, S.3
Ye, T.-Z.4
Ellis, N.A.5
-
36
-
-
0034650238
-
WRN helicase expression in Werner syndrome cell lines
-
Moser M.J., Kamath-Loeb A.S., Jacob J.E., et al. WRN helicase expression in Werner syndrome cell lines. Nucleic Acids Res 2000, 28:648-654.
-
(2000)
Nucleic Acids Res
, vol.28
, pp. 648-654
-
-
Moser, M.J.1
Kamath-Loeb, A.S.2
Jacob, J.E.3
-
37
-
-
77954025436
-
WRN mutations in Werner syndrome patients: genomic rearrangements, unusual intronic mutations and ethnic-specific alterations
-
Friedrich K., Lee L., Leistritz D., et al. WRN mutations in Werner syndrome patients: genomic rearrangements, unusual intronic mutations and ethnic-specific alterations. Human Genet 2010, 128(1):103-111.
-
(2010)
Human Genet
, vol.128
, Issue.1
, pp. 103-111
-
-
Friedrich, K.1
Lee, L.2
Leistritz, D.3
-
38
-
-
0042736696
-
LMNA mutations in atypical Werner's syndrome
-
Chen L., Lee L., Kudlow B.A., et al. LMNA mutations in atypical Werner's syndrome. Lancet 2003, 362(9382):440-445.
-
(2003)
Lancet
, vol.362
, Issue.9382
, pp. 440-445
-
-
Chen, L.1
Lee, L.2
Kudlow, B.A.3
-
39
-
-
1842685207
-
The Werner syndrome protein has separable recombination and viability functions
-
Swanson C., Saintigny Y., Emond M.J., Monnat R.J. The Werner syndrome protein has separable recombination and viability functions. DNA Repair 2004, 3:475-482.
-
(2004)
DNA Repair
, vol.3
, pp. 475-482
-
-
Swanson, C.1
Saintigny, Y.2
Emond, M.J.3
Monnat, R.J.4
-
40
-
-
0032808411
-
Cell fusion corrects the 4-nitroquinoline 1-oxide sensitivity of Werner syndrome fibroblast cell lines
-
Prince P.R., Ogburn C.E., Moser M.J., et al. Cell fusion corrects the 4-nitroquinoline 1-oxide sensitivity of Werner syndrome fibroblast cell lines. Human Genet 1999, 105:132-138.
-
(1999)
Human Genet
, vol.105
, pp. 132-138
-
-
Prince, P.R.1
Ogburn, C.E.2
Moser, M.J.3
-
41
-
-
0036308256
-
Intron-size constraint as a mutational mechanism in Rothmund-Thomson syndrome
-
Wang L.L., Worley K., Gannavarapu A., et al. Intron-size constraint as a mutational mechanism in Rothmund-Thomson syndrome. Am J Hum Genet 2002, 71(1):165-167.
-
(2002)
Am J Hum Genet
, vol.71
, Issue.1
, pp. 165-167
-
-
Wang, L.L.1
Worley, K.2
Gannavarapu, A.3
-
42
-
-
76749160296
-
Rothmund-Thomson syndrome helicase. RECQL4: on the crossroad between DNA replication and repair
-
Liu Y. Rothmund-Thomson syndrome helicase. RECQL4: on the crossroad between DNA replication and repair. DNA Repair 2010, 9:325-330.
-
(2010)
DNA Repair
, vol.9
, pp. 325-330
-
-
Liu, Y.1
-
43
-
-
11244258888
-
The enzymatic activities of the Werner syndrome protein are disabled by the amino acid polymorphism R834C
-
Kamath-Loeb A.S., Welcsh P., Waite M., Adman E.T., Loeb L.A. The enzymatic activities of the Werner syndrome protein are disabled by the amino acid polymorphism R834C. J Biol Chem 2004, 279(53):55499-55505.
-
(2004)
J Biol Chem
, vol.279
, Issue.53
, pp. 55499-55505
-
-
Kamath-Loeb, A.S.1
Welcsh, P.2
Waite, M.3
Adman, E.T.4
Loeb, L.A.5
-
44
-
-
0141567744
-
RecQ helicases: suppressors of tumorigenesis and premature aging
-
Bachrati C.Z., Hickson I.D. RecQ helicases: suppressors of tumorigenesis and premature aging. Biochem J 2003, 374:577-606.
-
(2003)
Biochem J
, vol.374
, pp. 577-606
-
-
Bachrati, C.Z.1
Hickson, I.D.2
-
45
-
-
62049085034
-
Dual DNA unwinding activities of the Rothmund-Thomson syndrome protein, RECQ4
-
Xu X., Liu Y. Dual DNA unwinding activities of the Rothmund-Thomson syndrome protein, RECQ4. EMBO J 2009, 28(5):568-577.
-
(2009)
EMBO J
, vol.28
, Issue.5
, pp. 568-577
-
-
Xu, X.1
Liu, Y.2
-
46
-
-
76749168005
-
Roles of Werner syndrome protein in protection of genome integrity
-
Rossi M.L., Ghosh A.K., Bohr V.A. Roles of Werner syndrome protein in protection of genome integrity. DNA Repair 2010, 9(3):331-344.
-
(2010)
DNA Repair
, vol.9
, Issue.3
, pp. 331-344
-
-
Rossi, M.L.1
Ghosh, A.K.2
Bohr, V.A.3
-
47
-
-
33845352895
-
Dynamic roles for G4 DNA in the biology of eukaryotic cells
-
Maizels N. Dynamic roles for G4 DNA in the biology of eukaryotic cells. Nat Struct Mol Biol 2006, 13(12):1055-1059.
-
(2006)
Nat Struct Mol Biol
, vol.13
, Issue.12
, pp. 1055-1059
-
-
Maizels, N.1
-
48
-
-
71449125359
-
Telomeric D-loops containing 8-oxo-2′-deoxyguanosine are preferred substrates for Werner and Bloom syndrome helicases and are bound by POT1
-
Ghosh A., Rossi M.L., Aulds J., Croteau D., Bohr V.A. Telomeric D-loops containing 8-oxo-2′-deoxyguanosine are preferred substrates for Werner and Bloom syndrome helicases and are bound by POT1. J Biol Chem 2009, 284(45):31074-31084.
-
(2009)
J Biol Chem
, vol.284
, Issue.45
, pp. 31074-31084
-
-
Ghosh, A.1
Rossi, M.L.2
Aulds, J.3
Croteau, D.4
Bohr, V.A.5
-
49
-
-
77955705802
-
WRN helicase unwinds Okazaki fragment-like hybrids in a reaction stimulated by the human DHX9 helicase
-
Chakraborty P., Grosse F. WRN helicase unwinds Okazaki fragment-like hybrids in a reaction stimulated by the human DHX9 helicase. Nucl Acids Res 2010, 38(14):4722-4730.
-
(2010)
Nucl Acids Res
, vol.38
, Issue.14
, pp. 4722-4730
-
-
Chakraborty, P.1
Grosse, F.2
-
50
-
-
0031686571
-
The premature aging syndrome protein, WRN, is a 3′ to 5′ exonuclease
-
Huang S., Li B., Gray M.D., et al. The premature aging syndrome protein, WRN, is a 3′ to 5′ exonuclease. Nat Genet 1998, 20:114-116.
-
(1998)
Nat Genet
, vol.20
, pp. 114-116
-
-
Huang, S.1
Li, B.2
Gray, M.D.3
-
51
-
-
0032545515
-
Werner syndrome protein I: DNA helicase and DNA exonuclease reside on the same polypeptide
-
Shen J.-C., Gray M.D., Oshima J., et al. Werner syndrome protein I: DNA helicase and DNA exonuclease reside on the same polypeptide. J Biol Chem 1998, 273:34139-34144.
-
(1998)
J Biol Chem
, vol.273
, pp. 34139-34144
-
-
Shen, J.-C.1
Gray, M.D.2
Oshima, J.3
-
52
-
-
0032545423
-
Werner syndrome protein II: characterization of the integral 3'→5' DNA exonuclease
-
Kamath-Loeb A.S., Shen J.-C., Loeb L.A., Fry M. Werner syndrome protein II: characterization of the integral 3'→5' DNA exonuclease. J Biol Chem 1998, 273:34145-34150.
-
(1998)
J Biol Chem
, vol.273
, pp. 34145-34150
-
-
Kamath-Loeb, A.S.1
Shen, J.-C.2
Loeb, L.A.3
Fry, M.4
-
53
-
-
34548759123
-
Emergence of a DNA-damage response network consisting of Fanconi anaemia and BRCA proteins
-
Wang W. Emergence of a DNA-damage response network consisting of Fanconi anaemia and BRCA proteins. Nat Rev Genet 2007, 8(10):735-748.
-
(2007)
Nat Rev Genet
, vol.8
, Issue.10
, pp. 735-748
-
-
Wang, W.1
-
54
-
-
0035377356
-
Potential role for the BLM helicase in recombinational repair via a conserved interaction with RAD51
-
Wu L., Davies S.L., Levitt N.C., Hickson I.D. Potential role for the BLM helicase in recombinational repair via a conserved interaction with RAD51. J Biol Chem 2001, 276(22):19375-19381.
-
(2001)
J Biol Chem
, vol.276
, Issue.22
, pp. 19375-19381
-
-
Wu, L.1
Davies, S.L.2
Levitt, N.C.3
Hickson, I.D.4
-
55
-
-
77649131406
-
Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis
-
Moynahan M.E., Jasin M. Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis. Nat Rev Mol Cell Biol 2010, 11(3):196-207.
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, Issue.3
, pp. 196-207
-
-
Moynahan, M.E.1
Jasin, M.2
-
56
-
-
47249106520
-
Werner protein cooperates with the XRCC4-DNA ligase IV complex in end-processing
-
Kusumoto R., Dawut L., Marchetti C., et al. Werner protein cooperates with the XRCC4-DNA ligase IV complex in end-processing. Biochemistry 2008, 47(28):7548-7556.
-
(2008)
Biochemistry
, vol.47
, Issue.28
, pp. 7548-7556
-
-
Kusumoto, R.1
Dawut, L.2
Marchetti, C.3
-
57
-
-
32644449296
-
The Werner syndrome protein operates in base excision repair and cooperates with DNA polymerase β
-
Harrigan J.A., Wilson D.M., Prasad R., et al. The Werner syndrome protein operates in base excision repair and cooperates with DNA polymerase β. Nucl Acids Res 2006, 34(2):745-754.
-
(2006)
Nucl Acids Res
, vol.34
, Issue.2
, pp. 745-754
-
-
Harrigan, J.A.1
Wilson, D.M.2
Prasad, R.3
-
58
-
-
0033621354
-
The Werner syndrome gene product co-purifies with the DNA replication complex and interacts with PCNA and topoisomerase I
-
Lebel M., Spillare E.A., Harris C.C., Leder P. The Werner syndrome gene product co-purifies with the DNA replication complex and interacts with PCNA and topoisomerase I. J Biol Chem 1999, 274:37795-37799.
-
(1999)
J Biol Chem
, vol.274
, pp. 37795-37799
-
-
Lebel, M.1
Spillare, E.A.2
Harris, C.C.3
Leder, P.4
-
59
-
-
0141480945
-
WRN interacts physically and functionally with the recombination mediator protein RAD52
-
Baynton K., Otterlei M., Bjørås M., et al. WRN interacts physically and functionally with the recombination mediator protein RAD52. J Biol Chem 2003, 278:36476-36486.
-
(2003)
J Biol Chem
, vol.278
, pp. 36476-36486
-
-
Baynton, K.1
Otterlei, M.2
Bjørås, M.3
-
60
-
-
33846141125
-
Werner syndrome protein participates in a complex with RAD51, RAD54, RAD54B and ATR in response to ICL-induced replication arrest
-
Otterlei M., Bruheim P., Ahn B., et al. Werner syndrome protein participates in a complex with RAD51, RAD54, RAD54B and ATR in response to ICL-induced replication arrest. J Cell Sci 2006, 119(24):5137-5146.
-
(2006)
J Cell Sci
, vol.119
, Issue.24
, pp. 5137-5146
-
-
Otterlei, M.1
Bruheim, P.2
Ahn, B.3
-
61
-
-
77749330814
-
The human RECQ1 and RECQ4 helicases play distinct roles in DNA replication initiation
-
Thangavel S., Mendoza-Maldonado R., Tissino E., et al. The human RECQ1 and RECQ4 helicases play distinct roles in DNA replication initiation. Mol Cell Biol 2009, 30(6):1382-1396.
-
(2009)
Mol Cell Biol
, vol.30
, Issue.6
, pp. 1382-1396
-
-
Thangavel, S.1
Mendoza-Maldonado, R.2
Tissino, E.3
-
62
-
-
70350573964
-
MCM10 mediates RECQ4 association with MCM2-7 helicase complex during DNA replication
-
Xu X., Rochette P.J., Feyissa E.A., Su T.V., Liu Y. MCM10 mediates RECQ4 association with MCM2-7 helicase complex during DNA replication. EMBO J 2009, 28(19):3005-3014.
-
(2009)
EMBO J
, vol.28
, Issue.19
, pp. 3005-3014
-
-
Xu, X.1
Rochette, P.J.2
Feyissa, E.A.3
Su, T.V.4
Liu, Y.5
-
63
-
-
36849013079
-
RECQL5/Recql5 helicase regulates homologous recombination and suppresses tumor formation via disruption of Rad51 presynaptic filaments
-
Hu Y., Raynard S., Sehorn M.G., et al. RECQL5/Recql5 helicase regulates homologous recombination and suppresses tumor formation via disruption of Rad51 presynaptic filaments. Genes Dev 2007, 21(23):3073-3084.
-
(2007)
Genes Dev
, vol.21
, Issue.23
, pp. 3073-3084
-
-
Hu, Y.1
Raynard, S.2
Sehorn, M.G.3
-
64
-
-
77952372219
-
Physical Interaction of RECQ5 helicase with RAD51 facilitates its anti-recombinase activity
-
Schwendener S., Raynard S., Paliwal S., et al. Physical Interaction of RECQ5 helicase with RAD51 facilitates its anti-recombinase activity. J Biol Chem 2010, 285(21):15739-15745.
-
(2010)
J Biol Chem
, vol.285
, Issue.21
, pp. 15739-15745
-
-
Schwendener, S.1
Raynard, S.2
Paliwal, S.3
-
65
-
-
77955738562
-
The Human WRN and BLM RecQ helicases differentially regulate cell proliferation and survival after chemotherapeutic DNA damage
-
Mao F.J., Sidorova J.M., Lauper J.M., Emond M.J., Monnat R.J. The Human WRN and BLM RecQ helicases differentially regulate cell proliferation and survival after chemotherapeutic DNA damage. Cancer Res 2010, 70(16):6548-6555.
-
(2010)
Cancer Res
, vol.70
, Issue.16
, pp. 6548-6555
-
-
Mao, F.J.1
Sidorova, J.M.2
Lauper, J.M.3
Emond, M.J.4
Monnat, R.J.5
-
66
-
-
0035871341
-
Loss of Werner syndrome protein function promotes aberrant mitotic recombination
-
Prince P.R., Emond M.J., Monnat R.J. Loss of Werner syndrome protein function promotes aberrant mitotic recombination. Genes Dev 2001, 15:933-938.
-
(2001)
Genes Dev
, vol.15
, pp. 933-938
-
-
Prince, P.R.1
Emond, M.J.2
Monnat, R.J.3
-
67
-
-
0036787870
-
Homologous recombination resolution defect in Werner syndrome
-
Saintigny Y., Makienko K., Swanson C., Emond M.J., Monnat R.J. Homologous recombination resolution defect in Werner syndrome. Mol Cell Biol 2002, 22(20):6971-6978.
-
(2002)
Mol Cell Biol
, vol.22
, Issue.20
, pp. 6971-6978
-
-
Saintigny, Y.1
Makienko, K.2
Swanson, C.3
Emond, M.J.4
Monnat, R.J.5
-
68
-
-
70350355118
-
Bloom syndrome helicase stimulates RAD51 DNA strand exchange activity through a novel mechanism
-
Bugreev D.V., Mazina O.M., Mazin A.V. Bloom syndrome helicase stimulates RAD51 DNA strand exchange activity through a novel mechanism. J Biol Chem 2009, 284(39):26349-26359.
-
(2009)
J Biol Chem
, vol.284
, Issue.39
, pp. 26349-26359
-
-
Bugreev, D.V.1
Mazina, O.M.2
Mazin, A.V.3
-
69
-
-
77955919033
-
BLM has early and late functions in homologous recombination repair in mouse embryonic stem cells
-
Chu W.K., Hanada K., Kanaar R., Hickson I.D. BLM has early and late functions in homologous recombination repair in mouse embryonic stem cells. Oncogene 2010, 29(33):4705-4714.
-
(2010)
Oncogene
, vol.29
, Issue.33
, pp. 4705-4714
-
-
Chu, W.K.1
Hanada, K.2
Kanaar, R.3
Hickson, I.D.4
-
70
-
-
55949105327
-
Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair
-
Nimonkar A.V., Özsoy A.Z., Genschel J., Modrich P., Kowalczykowski S.C. Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair. Proc Natl Acad Sci U S A 2008, 105(44):16906-16911.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.44
, pp. 16906-16911
-
-
Nimonkar, A.V.1
Özsoy, A.Z.2
Genschel, J.3
Modrich, P.4
Kowalczykowski, S.C.5
-
71
-
-
53649090109
-
DNA helicases Sgs1 and BLM promote DNA double-strand break resection
-
Gravel S., Chapman J.R., Magill C., Jackson S.P. DNA helicases Sgs1 and BLM promote DNA double-strand break resection. Genes Dev 2008, 22(20):2767-2772.
-
(2008)
Genes Dev
, vol.22
, Issue.20
, pp. 2767-2772
-
-
Gravel, S.1
Chapman, J.R.2
Magill, C.3
Jackson, S.P.4
-
72
-
-
41649103456
-
Wrestling off RAD51: a novel role for RecQ helicases
-
Wu L. Wrestling off RAD51: a novel role for RecQ helicases. BioEssays 2008, 30(4):291-295.
-
(2008)
BioEssays
, vol.30
, Issue.4
, pp. 291-295
-
-
Wu, L.1
-
73
-
-
77953590923
-
Delineation of WRN helicase function with EXO1 in the replicational stress response
-
Aggarwal M., Sommers J.A., Morris C., Brosh J. Delineation of WRN helicase function with EXO1 in the replicational stress response. DNA Repair 2010, 9(7):765-776.
-
(2010)
DNA Repair
, vol.9
, Issue.7
, pp. 765-776
-
-
Aggarwal, M.1
Sommers, J.A.2
Morris, C.3
Brosh, J.4
-
74
-
-
0347987856
-
The Bloom's syndrome helicase suppresses crossing over during homologous recombination
-
Wu L., Hickson I.D. The Bloom's syndrome helicase suppresses crossing over during homologous recombination. Nature 2003, 426:870-874.
-
(2003)
Nature
, vol.426
, pp. 870-874
-
-
Wu, L.1
Hickson, I.D.2
-
75
-
-
33746600628
-
Topoisomerase IIIα and Bloom helicase can resolve a mobile double Holliday junction substrate through convergent branch migration
-
Plank J.L., Wu J., Hsieh Ts. Topoisomerase IIIα and Bloom helicase can resolve a mobile double Holliday junction substrate through convergent branch migration. Proc Natl Acad Sci U S A 2006, 103(30):11118-11123.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, Issue.30
, pp. 11118-11123
-
-
Plank, J.L.1
Wu, J.2
Hsieh, T.3
-
76
-
-
33645242115
-
BLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediates
-
Wu L., Bachrati C.Z., Ou J., et al. BLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediates. Proc Natl Acad Sci U S A 2006, 103(11):4068-4073.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, Issue.11
, pp. 4068-4073
-
-
Wu, L.1
Bachrati, C.Z.2
Ou, J.3
-
77
-
-
77949420670
-
GEN1/Yen1 and the SLX4 complex: solutions to the problem of Holliday junction resolution
-
Svendsen J.M., Harper J.W. GEN1/Yen1 and the SLX4 complex: solutions to the problem of Holliday junction resolution. Genes Dev 2010, 24(6):521-536.
-
(2010)
Genes Dev
, vol.24
, Issue.6
, pp. 521-536
-
-
Svendsen, J.M.1
Harper, J.W.2
-
78
-
-
78149425175
-
Regulation of homologous recombination in eukaryotes
-
Heyer W.-D., Ehmsen K.T., Liu J. Regulation of homologous recombination in eukaryotes. Annu Rev Genet 2010, 44:113-139.
-
(2010)
Annu Rev Genet
, vol.44
, pp. 113-139
-
-
Heyer, W.-D.1
Ehmsen, K.T.2
Liu, J.3
-
79
-
-
2442660468
-
Linkage between Werner syndrome protein and the Mre11 complex via Nbs1
-
Cheng W.H., von Kobbe C., Opresko P.L., et al. Linkage between Werner syndrome protein and the Mre11 complex via Nbs1. J Biol Chem 2004, 279(20):21169-21176.
-
(2004)
J Biol Chem
, vol.279
, Issue.20
, pp. 21169-21176
-
-
Cheng, W.H.1
von Kobbe, C.2
Opresko, P.L.3
-
80
-
-
1842791545
-
Identification and biochemical characterization of a Werner's syndrome protein complex with Ku70/80 and poly (ADP-ribose) polymerase-1
-
Li B., Navarro S., Kasahara N., Comai L. Identification and biochemical characterization of a Werner's syndrome protein complex with Ku70/80 and poly (ADP-ribose) polymerase-1. J Biol Chem 2004, 279(14):13659-13667.
-
(2004)
J Biol Chem
, vol.279
, Issue.14
, pp. 13659-13667
-
-
Li, B.1
Navarro, S.2
Kasahara, N.3
Comai, L.4
-
81
-
-
11144233626
-
Regulation of WRN helicase activity in human base excision repair
-
Ahn B., Harrigan J.A., Indig F.E., Wilson D.M., Bohr V.A. Regulation of WRN helicase activity in human base excision repair. J Biol Chem 2004, 279(51):53465-53474.
-
(2004)
J Biol Chem
, vol.279
, Issue.51
, pp. 53465-53474
-
-
Ahn, B.1
Harrigan, J.A.2
Indig, F.E.3
Wilson, D.M.4
Bohr, V.A.5
-
82
-
-
5044247389
-
Database of mouse strains carrying targeted mutations in genes affecting biological responses to DNA damage (Version 6)
-
Friedberg E.C., Meira L.B. Database of mouse strains carrying targeted mutations in genes affecting biological responses to DNA damage (Version 6). DNA Repair 2004, 3(12):1617-1638.
-
(2004)
DNA Repair
, vol.3
, Issue.12
, pp. 1617-1638
-
-
Friedberg, E.C.1
Meira, L.B.2
-
83
-
-
53149151798
-
Roles of the Werner syndrome RecQ helicase in DNA replication
-
Sidorova J.M. Roles of the Werner syndrome RecQ helicase in DNA replication. DNA Repair 2008, 7:1776-1786.
-
(2008)
DNA Repair
, vol.7
, pp. 1776-1786
-
-
Sidorova, J.M.1
-
84
-
-
34547132330
-
Endogenous g-H2AX-ATM-Chk2 checkpoint activation in Bloom's Syndrome helicase-deficient cells is related to DNA replication arrested forks
-
Rao V.A., Conti C., Guirouilh-Barbat J., et al. Endogenous g-H2AX-ATM-Chk2 checkpoint activation in Bloom's Syndrome helicase-deficient cells is related to DNA replication arrested forks. Mol Cancer Res 2007, 5(7):713-724.
-
(2007)
Mol Cancer Res
, vol.5
, Issue.7
, pp. 713-724
-
-
Rao, V.A.1
Conti, C.2
Guirouilh-Barbat, J.3
-
85
-
-
34447115757
-
Role for BLM in replication-fork restart and suppression of origin firing after replicative stress
-
Davies S.L., North P.S., Hickson I.D. Role for BLM in replication-fork restart and suppression of origin firing after replicative stress. Nat Struct Mol Biol 2007, 14(7):677-679.
-
(2007)
Nat Struct Mol Biol
, vol.14
, Issue.7
, pp. 677-679
-
-
Davies, S.L.1
North, P.S.2
Hickson, I.D.3
-
86
-
-
42049116919
-
The RecQ helicase WRN is required for normal replication fork progression after DNA damage or replication fork arrest
-
Sidorova J.M., Li N., Folch A., Monnat R.J. The RecQ helicase WRN is required for normal replication fork progression after DNA damage or replication fork arrest. Cell Cycle 2008, 7:796-807.
-
(2008)
Cell Cycle
, vol.7
, pp. 796-807
-
-
Sidorova, J.M.1
Li, N.2
Folch, A.3
Monnat, R.J.4
-
87
-
-
36749022214
-
The DNA damage response: ten years after
-
Harper J.W., Elledge S.J. The DNA damage response: ten years after. Mol Cell 2007, 28:739-745.
-
(2007)
Mol Cell
, vol.28
, pp. 739-745
-
-
Harper, J.W.1
Elledge, S.J.2
-
88
-
-
77951974344
-
Dealing with DNA damage: relationships between checkpoint and repair pathways
-
Warmerdam D.O., Kanaar R. Dealing with DNA damage: relationships between checkpoint and repair pathways. Mut Res/Rev Mut Res 2010, 704(1-3):2-11.
-
(2010)
Mut Res/Rev Mut Res
, vol.704
, Issue.1-3
, pp. 2-11
-
-
Warmerdam, D.O.1
Kanaar, R.2
-
89
-
-
0037435026
-
Werner's syndrome protein is phosphorylated in an ATR/ATM-dependent manner following replication arrest and DNA damage induced during S-phase of the cell cycle
-
Pichierri P., Rosselli F., Franchitto A. Werner's syndrome protein is phosphorylated in an ATR/ATM-dependent manner following replication arrest and DNA damage induced during S-phase of the cell cycle. Oncogene 2003, 22:1491-1500.
-
(2003)
Oncogene
, vol.22
, pp. 1491-1500
-
-
Pichierri, P.1
Rosselli, F.2
Franchitto, A.3
-
90
-
-
1642458364
-
Phosphorylation of the Bloom's Syndrome helicase and its role in recovery from S-phase arrest
-
Davies S.L., North P.S., Dart A., Lakin N.D., Hickson I.D. Phosphorylation of the Bloom's Syndrome helicase and its role in recovery from S-phase arrest. Mol Cell Biol 2004, 24(3):1279-1291.
-
(2004)
Mol Cell Biol
, vol.24
, Issue.3
, pp. 1279-1291
-
-
Davies, S.L.1
North, P.S.2
Dart, A.3
Lakin, N.D.4
Hickson, I.D.5
-
91
-
-
73949087271
-
SUMO modification regulates BLM and RAD51 interaction at damaged replication forks
-
Ouyang K.J., Woo L.L., Zhu J., et al. SUMO modification regulates BLM and RAD51 interaction at damaged replication forks. PLoS Biol 2009, 7(12):e1000252.
-
(2009)
PLoS Biol
, vol.7
, Issue.12
-
-
Ouyang, K.J.1
Woo, L.L.2
Zhu, J.3
-
92
-
-
55549147927
-
WRN Is required for ATM activation and the S-phase checkpoint in response to interstrand cross-link-induced DNA double-strand breaks
-
Cheng W.H., Muftic D., Muftuoglu M., et al. WRN Is required for ATM activation and the S-phase checkpoint in response to interstrand cross-link-induced DNA double-strand breaks. Mol Biol Cell 2008, 19(9):3923-3933.
-
(2008)
Mol Biol Cell
, vol.19
, Issue.9
, pp. 3923-3933
-
-
Cheng, W.H.1
Muftic, D.2
Muftuoglu, M.3
-
93
-
-
0033553536
-
Mammalian telomeres end in a large duplex loop
-
Griffith J.D., Comeau L., Rosenfield S., et al. Mammalian telomeres end in a large duplex loop. Cell 1999, 97(4):503-514.
-
(1999)
Cell
, vol.97
, Issue.4
, pp. 503-514
-
-
Griffith, J.D.1
Comeau, L.2
Rosenfield, S.3
-
94
-
-
77649180958
-
Telomeres: protecting chromosomes against genomic instability
-
O'Sullivan R.J., Karlseder J. Telomeres: protecting chromosomes against genomic instability. Nat Rev Mol Cell Biol 2010, 11:171-181.
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, pp. 171-181
-
-
O'Sullivan, R.J.1
Karlseder, J.2
-
95
-
-
38949094875
-
Telomere ResQue and preservation-roles for the Werner syndrome protein and other RecQ helicases
-
Opresko P.L. Telomere ResQue and preservation-roles for the Werner syndrome protein and other RecQ helicases. Mech Ageing Dev 2008, 129(1-2):79-90.
-
(2008)
Mech Ageing Dev
, vol.129
, Issue.1-2
, pp. 79-90
-
-
Opresko, P.L.1
-
96
-
-
10344256183
-
Defective telomere lagging strand synthesis in cells lacking WRN helicase activity
-
Crabbe L., Verdun R.E., Haggblom C.I., Karlseder J. Defective telomere lagging strand synthesis in cells lacking WRN helicase activity. Science 2004, 306(5703):1951-1953.
-
(2004)
Science
, vol.306
, Issue.5703
, pp. 1951-1953
-
-
Crabbe, L.1
Verdun, R.E.2
Haggblom, C.I.3
Karlseder, J.4
-
97
-
-
33847790504
-
Telomere dysfunction as a cause of genomic instability in Werner syndrome
-
Crabbe L., Jauch A., Naeger C.M., Holtgreve-Grez H., Karlseder J. Telomere dysfunction as a cause of genomic instability in Werner syndrome. Proc Natl Acad Sci U S A 2007, 104(7):2205-2210.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, Issue.7
, pp. 2205-2210
-
-
Crabbe, L.1
Jauch, A.2
Naeger, C.M.3
Holtgreve-Grez, H.4
Karlseder, J.5
-
98
-
-
3543043128
-
Essential role of limiting telomeres in the pathogenesis of Werner syndrome
-
Chang S., Multani A.S., Cabrera N.G., et al. Essential role of limiting telomeres in the pathogenesis of Werner syndrome. Nat Genet 2004, 36(8):877-882.
-
(2004)
Nat Genet
, vol.36
, Issue.8
, pp. 877-882
-
-
Chang, S.1
Multani, A.S.2
Cabrera, N.G.3
-
99
-
-
4544301617
-
Telomere shortening exposes functions for the mouse Werner and Bloom Syndrome genes
-
Du X., Shen J., Kugan N., et al. Telomere shortening exposes functions for the mouse Werner and Bloom Syndrome genes. Mol Cell Biol 2004, 24(19):8437-8446.
-
(2004)
Mol Cell Biol
, vol.24
, Issue.19
, pp. 8437-8446
-
-
Du, X.1
Shen, J.2
Kugan, N.3
-
100
-
-
74049111326
-
Telomeres and telomerase in cancer
-
Artandi S.E., DePinho R.A. Telomeres and telomerase in cancer. Carcinogenesis 2010, 31(1):9-18.
-
(2010)
Carcinogenesis
, vol.31
, Issue.1
, pp. 9-18
-
-
Artandi, S.E.1
DePinho, R.A.2
-
101
-
-
73849113505
-
Unwinding protein complexes in ALTernative telomere maintenance
-
Bhattacharyya S., Sandy A., Groden J. Unwinding protein complexes in ALTernative telomere maintenance. J Cell Biochem 2010, 109(1):7-15.
-
(2010)
J Cell Biochem
, vol.109
, Issue.1
, pp. 7-15
-
-
Bhattacharyya, S.1
Sandy, A.2
Groden, J.3
-
102
-
-
0014816132
-
Replicative life-span of cultivated human cells. Effects of donor's age, tissue, and genotype
-
Martin G.M., Sprague C.A., Epstein C.J. Replicative life-span of cultivated human cells. Effects of donor's age, tissue, and genotype. Lab Invest 1970, 23:86-92.
-
(1970)
Lab Invest
, vol.23
, pp. 86-92
-
-
Martin, G.M.1
Sprague, C.A.2
Epstein, C.J.3
-
103
-
-
33846428068
-
Functional role of the Werner syndrome RecQ helicase in human fibroblasts
-
Dhillon K.K., Sidorova J., Saintigny Y., et al. Functional role of the Werner syndrome RecQ helicase in human fibroblasts. Aging Cell 2007, 6(1):53-61.
-
(2007)
Aging Cell
, vol.6
, Issue.1
, pp. 53-61
-
-
Dhillon, K.K.1
Sidorova, J.2
Saintigny, Y.3
-
104
-
-
34547192058
-
BLM is required for faithful chromosome segregation and its localization defines a class of ultrafine anaphase bridges
-
Chan K.L., North P.S., Hickson I.D. BLM is required for faithful chromosome segregation and its localization defines a class of ultrafine anaphase bridges. EMBO J 2007, 26(14):3397-3409.
-
(2007)
EMBO J
, vol.26
, Issue.14
, pp. 3397-3409
-
-
Chan, K.L.1
North, P.S.2
Hickson, I.D.3
-
105
-
-
77949704890
-
The Bloom syndrome protein limits the lethality associated with RAD51 deficiency
-
Lahkim Bennani-Belhaj K., Rouzeau S, Buhagiar-Labarchede G., et al. The Bloom syndrome protein limits the lethality associated with RAD51 deficiency. Mol Cancer Res 2010, 8(3):385-394.
-
(2010)
Mol Cancer Res
, vol.8
, Issue.3
, pp. 385-394
-
-
Lahkim Bennani-Belhaj, K.1
Rouzeau, S.2
Buhagiar-Labarchede, G.3
-
106
-
-
0016678691
-
Variegated translocation mosaicism in human skin fibroblast cultures
-
Hoehn H., Bryant E.M., Au K., et al. Variegated translocation mosaicism in human skin fibroblast cultures. Cytogenet Cell Genet 1975, 15:282-298.
-
(1975)
Cytogenet Cell Genet
, vol.15
, pp. 282-298
-
-
Hoehn, H.1
Bryant, E.M.2
Au, K.3
-
107
-
-
0022322386
-
Cytogenetic aspects of Werner syndrome
-
Salk D., Au K., Hoehn H., Martin G.M. Cytogenetic aspects of Werner syndrome. Adv Exp Med Biol 1985, 190:541-546.
-
(1985)
Adv Exp Med Biol
, vol.190
, pp. 541-546
-
-
Salk, D.1
Au, K.2
Hoehn, H.3
Martin, G.M.4
-
108
-
-
0033820714
-
Analysis of genomic instability using multiple assays in a patient with Rothmund-Thomson syndrome
-
Grant S., Wenger S., Latimer J., Thull D., Burke L. Analysis of genomic instability using multiple assays in a patient with Rothmund-Thomson syndrome. Clin Genet 2000, 58(3):209-215.
-
(2000)
Clin Genet
, vol.58
, Issue.3
, pp. 209-215
-
-
Grant, S.1
Wenger, S.2
Latimer, J.3
Thull, D.4
Burke, L.5
-
109
-
-
62549112664
-
Recurrent RECQL4 imbalance and increased gene expression levels are associated with structural chromosomal instability in sporadic osteosarcoma
-
Maire G., Yoshimoto M., Chilton-MacNeill S., et al. Recurrent RECQL4 imbalance and increased gene expression levels are associated with structural chromosomal instability in sporadic osteosarcoma. Neoplasia 2009, 11:260-268.
-
(2009)
Neoplasia
, vol.11
, pp. 260-268
-
-
Maire, G.1
Yoshimoto, M.2
Chilton-MacNeill, S.3
-
110
-
-
0033511453
-
Growth deficiency and malnutrition in Bloom syndrome
-
Keller C., Keller K.R., Shew S.B., Plon S.E. Growth deficiency and malnutrition in Bloom syndrome. J Pediatr 1999, 134(4):472-479.
-
(1999)
J Pediatr
, vol.134
, Issue.4
, pp. 472-479
-
-
Keller, C.1
Keller, K.R.2
Shew, S.B.3
Plon, S.E.4
-
111
-
-
34547810916
-
From broken to old: DNA damage. IGF1 endocrine suppression and aging
-
Monnat R.J. From broken to old: DNA damage. IGF1 endocrine suppression and aging. DNA Repair 2007, 6(9):1386-1390.
-
(2007)
DNA Repair
, vol.6
, Issue.9
, pp. 1386-1390
-
-
Monnat, R.J.1
-
112
-
-
55549116359
-
DNA damage and ageing: new-age ideas for an age-old problem
-
Garinis G.A., van der Horst G.T.J., Vijg J., Hoeijmakers H.J. DNA damage and ageing: new-age ideas for an age-old problem. Nat Cell Biol 2008, 10(11):1241-1247.
-
(2008)
Nat Cell Biol
, vol.10
, Issue.11
, pp. 1241-1247
-
-
Garinis, G.A.1
van der Horst, G.T.J.2
Vijg, J.3
Hoeijmakers, H.J.4
-
113
-
-
45849099050
-
Living on a break: cellular senescence as a DNA-damage response
-
Adda di Fagagna F. Living on a break: cellular senescence as a DNA-damage response. Nat Rev Cancer 2008, 8(7):512-522.
-
(2008)
Nat Rev Cancer
, vol.8
, Issue.7
, pp. 512-522
-
-
Adda di Fagagna, F.1
-
114
-
-
33846090789
-
Accumulation of senescent cells in mitotic tissue of aging primates
-
Jeyapalan J.C., Ferreira M., Sedivy J.M., Herbig U. Accumulation of senescent cells in mitotic tissue of aging primates. Mech Ageing Dev 2007, 128(1):36-44.
-
(2007)
Mech Ageing Dev
, vol.128
, Issue.1
, pp. 36-44
-
-
Jeyapalan, J.C.1
Ferreira, M.2
Sedivy, J.M.3
Herbig, U.4
-
115
-
-
77952105389
-
Inflammatory networks during cellular senescence: causes and consequences
-
Freund A., Orjalo A.V., Desprez P.Y., Campisi J. Inflammatory networks during cellular senescence: causes and consequences. Trends Mol Med 2010, 16(5):238-246.
-
(2010)
Trends Mol Med
, vol.16
, Issue.5
, pp. 238-246
-
-
Freund, A.1
Orjalo, A.V.2
Desprez, P.Y.3
Campisi, J.4
-
116
-
-
72949096792
-
Senescence in tumours: evidence from mice and humans
-
Collado M., Serrano M. Senescence in tumours: evidence from mice and humans. Nat Rev Cancer 2010, 10(1):51-57.
-
(2010)
Nat Rev Cancer
, vol.10
, Issue.1
, pp. 51-57
-
-
Collado, M.1
Serrano, M.2
-
117
-
-
0034194139
-
Genetic instability and hematologic disease risk in Werner syndrome patients and heterozygotes
-
Moser M.J., Bigbee W.L., Grant S.G., et al. Genetic instability and hematologic disease risk in Werner syndrome patients and heterozygotes. Cancer Res 2000, 60:2492-2496.
-
(2000)
Cancer Res
, vol.60
, pp. 2492-2496
-
-
Moser, M.J.1
Bigbee, W.L.2
Grant, S.G.3
-
118
-
-
0031453968
-
An apoptosis-inducing genotoxin differentiates heterozygotic carriers for Werner helicase mutations from wild-type and homozygous mutants
-
Ogburn C.E., Oshima J., Poot M., et al. An apoptosis-inducing genotoxin differentiates heterozygotic carriers for Werner helicase mutations from wild-type and homozygous mutants. Hum Genet 1997, 101:121-125.
-
(1997)
Hum Genet
, vol.101
, pp. 121-125
-
-
Ogburn, C.E.1
Oshima, J.2
Poot, M.3
-
119
-
-
0010562243
-
Werner syndrome
-
McGraw-Hill, New York, C.R. Scriver, A.L. Beaudet, W.S. Sly, D. Valle (Eds.)
-
Schellenberg G.D., Miki T., Yu C.-E., Nakura J. Werner syndrome. The Metabolic & Molecular Basis of Inherited Disease 2001, 785-797. McGraw-Hill, New York. C.R. Scriver, A.L. Beaudet, W.S. Sly, D. Valle (Eds.).
-
(2001)
The Metabolic & Molecular Basis of Inherited Disease
, pp. 785-797
-
-
Schellenberg, G.D.1
Miki, T.2
Yu, C.-E.3
Nakura, J.4
-
120
-
-
33745056414
-
Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer
-
Agrelo R., Cheng W.H., Setien F., et al. Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer. Proc Natl Acad Sci U S A 2006, 103(23):8822-8827.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, Issue.23
, pp. 8822-8827
-
-
Agrelo, R.1
Cheng, W.H.2
Setien, F.3
-
121
-
-
38649135425
-
WRN promoter methylation possibly connects mucinous differentiation, microsatellite instability and CpG island methylator phenotype in colorectal cancer
-
Kawasaki T., Ohnishi M., Suemoto Y., et al. WRN promoter methylation possibly connects mucinous differentiation, microsatellite instability and CpG island methylator phenotype in colorectal cancer. Mod Pathol 2007, 21:150-158.
-
(2007)
Mod Pathol
, vol.21
, pp. 150-158
-
-
Kawasaki, T.1
Ohnishi, M.2
Suemoto, Y.3
-
122
-
-
65349085023
-
Hitting the bull's eye: novel directed cancer therapy through helicase-targeted synthetic lethality
-
Aggarwal M., Brosh R.M. Hitting the bull's eye: novel directed cancer therapy through helicase-targeted synthetic lethality. J Cell Biochem 2009, 106:758-763.
-
(2009)
J Cell Biochem
, vol.106
, pp. 758-763
-
-
Aggarwal, M.1
Brosh, R.M.2
-
123
-
-
44449156516
-
Helicases as prospective targets for anti-cancer therapy
-
Gupta R., Brosh R.M. Helicases as prospective targets for anti-cancer therapy. Anticancer Agents Med Chem 2008, 8:390-401.
-
(2008)
Anticancer Agents Med Chem
, vol.8
, pp. 390-401
-
-
Gupta, R.1
Brosh, R.M.2
-
124
-
-
42649123980
-
Amplifying tumour-specific replication lesions by DNA repair inhibitors-a new era in targeted cancer therapy
-
Helleday T. Amplifying tumour-specific replication lesions by DNA repair inhibitors-a new era in targeted cancer therapy. Eur J Cancer 2008, 44(7):921-927.
-
(2008)
Eur J Cancer
, vol.44
, Issue.7
, pp. 921-927
-
-
Helleday, T.1
-
125
-
-
25444497278
-
The concept of synthetic lethality in the context of anticancer therapy
-
Kaelin W.G. The concept of synthetic lethality in the context of anticancer therapy. Nat Rev Cancer 2005, 5(9):689-698.
-
(2005)
Nat Rev Cancer
, vol.5
, Issue.9
, pp. 689-698
-
-
Kaelin, W.G.1
-
126
-
-
43749120045
-
DNA repair deficiency as a therapeutic target in cancer
-
Martin S.A., Lord C.J., Ashworth A. DNA repair deficiency as a therapeutic target in cancer. Curr Opin Genet Dev 2008, 18(1):80-86.
-
(2008)
Curr Opin Genet Dev
, vol.18
, Issue.1
, pp. 80-86
-
-
Martin, S.A.1
Lord, C.J.2
Ashworth, A.3
-
127
-
-
39749166975
-
DNA repair pathways as targets for cancer therapy
-
Helleday T., Petermann E., Lundin C., Hodgson B., Sharma R.A. DNA repair pathways as targets for cancer therapy. Nat Rev Cancer 2008, 8(3):193-204.
-
(2008)
Nat Rev Cancer
, vol.8
, Issue.3
, pp. 193-204
-
-
Helleday, T.1
Petermann, E.2
Lundin, C.3
Hodgson, B.4
Sharma, R.A.5
-
128
-
-
73949118293
-
Genomic instability and the selection of treatments for cancer
-
Martin S.A., Hewish M., Lord C.J., Ashworth A. Genomic instability and the selection of treatments for cancer. J Pathol 2010, 220(2):281-289.
-
(2010)
J Pathol
, vol.220
, Issue.2
, pp. 281-289
-
-
Martin, S.A.1
Hewish, M.2
Lord, C.J.3
Ashworth, A.4
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