GPHMM: An integrated hidden Markov model for identification of copy number alteration and loss of heterozygosity in complex tumor samples using whole genome SNP arrays

Nucleic Acids Research

Volumn 39, Issue 12, 2011, Pages 4928-4941

  Li, Ao ^a,b   Liu, Zongzhi ^b   Lezon Geyda, Kimberly ^c   Sarkar, Sudipa ^b   Lannin, Donald ^b   Schulz, Vincent ^b   Krop, Ian ^d   Winer, Eric ^d   Harris, Lyndsay ^c   Tuck, David ^b  

^a UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c YALE CANCER CENTER   (United States)

^d DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALGORITHM; ARTICLE; BREAST CANCER; CANCER CELL; CANCER CELL CULTURE; CHROMOSOME 11; CHROMOSOME 17; CHROMOSOME 8; CHROMOSOME ABERRATION; COHORT ANALYSIS; CONTROLLED STUDY; FLUORESCENCE IN SITU HYBRIDIZATION; GENE DOSAGE; GENOME; GENOTYPE; GLOBAL PARAMETER HIDDEN MARKOV MODEL; HETEROZYGOSITY; HETEROZYGOSITY LOSS; HIDDEN MARKOV MODEL; HUMAN; HUMAN CELL; HUMAN TISSUE; MATHEMATICAL ANALYSIS; PRIORITY JOURNAL; QUALITY CONTROL; QUANTITATIVE ANALYSIS; SIGNAL NOISE RATIO; SINGLE NUCLEOTIDE POLYMORPHISM;

ALGORITHMS; BREAST NEOPLASMS; CELL LINE, TUMOR; DNA COPY NUMBER VARIATIONS; FEMALE; GENE DOSAGE; GENES, ERBB-2; GENOME, HUMAN; HUMANS; LOSS OF HETEROZYGOSITY; MARKOV CHAINS; NEOPLASMS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 79960268207     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkr014     Document Type: Article

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