-
2
-
-
77049303181
-
Somatic mosaicism for antigen A2
-
Cotterman C.W. Somatic mosaicism for antigen A2. Acta Genet. Stat. Med. 1956, 6:520-521.
-
(1956)
Acta Genet. Stat. Med.
, vol.6
, pp. 520-521
-
-
Cotterman, C.W.1
-
3
-
-
79956308553
-
Chemically induced somatic and gonadal mosaicism in Drosophila I. Sex-linked lethals
-
Carlson E.A., Southin J.L. Chemically induced somatic and gonadal mosaicism in Drosophila I. Sex-linked lethals. Genetics 1963, 48:663-675.
-
(1963)
Genetics
, vol.48
, pp. 663-675
-
-
Carlson, E.A.1
Southin, J.L.2
-
4
-
-
0013791938
-
Paramutation and somatic mosaicism in maize
-
Sastry G.R., et al. Paramutation and somatic mosaicism in maize. Genetics 1965, 52:407-424.
-
(1965)
Genetics
, vol.52
, pp. 407-424
-
-
Sastry, G.R.1
-
5
-
-
78649251520
-
The origins and implications of intratumor heterogeneity
-
Michor F., Polyak K. The origins and implications of intratumor heterogeneity. Cancer Prev. Res. (Phila) 2010, 3:1361-1364.
-
(2010)
Cancer Prev. Res. (Phila)
, vol.3
, pp. 1361-1364
-
-
Michor, F.1
Polyak, K.2
-
6
-
-
77951702343
-
Genetic heterogeneity in human disease
-
McClellan J., King M.C. Genetic heterogeneity in human disease. Cell 2010, 141:210-217.
-
(2010)
Cell
, vol.141
, pp. 210-217
-
-
McClellan, J.1
King, M.C.2
-
7
-
-
0036789093
-
Mechanisms and consequences of somatic mosaicism in humans
-
Youssoufian H., Pyeritz R.E. Mechanisms and consequences of somatic mosaicism in humans. Nat. Rev. Genet. 2002, 3:748-758.
-
(2002)
Nat. Rev. Genet.
, vol.3
, pp. 748-758
-
-
Youssoufian, H.1
Pyeritz, R.E.2
-
8
-
-
0023135430
-
Mutation rate of normal and malignant human lymphocytes
-
Seshadri R., et al. Mutation rate of normal and malignant human lymphocytes. Cancer Res. 1987, 47:407-409.
-
(1987)
Cancer Res.
, vol.47
, pp. 407-409
-
-
Seshadri, R.1
-
9
-
-
67649790837
-
Understanding what determines the frequency and pattern of human germline mutations
-
Arnheim N., Calabrese P. Understanding what determines the frequency and pattern of human germline mutations. Nat. Rev. Genet. 2009, 10:478-488.
-
(2009)
Nat. Rev. Genet.
, vol.10
, pp. 478-488
-
-
Arnheim, N.1
Calabrese, P.2
-
10
-
-
78649264297
-
De novo rates and selection of large copy number variation
-
Itsara A., et al. De novo rates and selection of large copy number variation. Genome Res. 2010, 20:1469-1481.
-
(2010)
Genome Res.
, vol.20
, pp. 1469-1481
-
-
Itsara, A.1
-
11
-
-
34347349069
-
Genomic rearrangements and sporadic disease
-
Lupski J.R. Genomic rearrangements and sporadic disease. Nat. Genet. 2007, 39:S43-47.
-
(2007)
Nat. Genet.
, vol.39
-
-
Lupski, J.R.1
-
12
-
-
16844371343
-
Frequency of new copy number variation in humans
-
van Ommen G.J. Frequency of new copy number variation in humans. Nat. Genet. 2005, 37:333-334.
-
(2005)
Nat. Genet.
, vol.37
, pp. 333-334
-
-
van Ommen, G.J.1
-
13
-
-
34447320759
-
L1 retrotransposition can occur early in human embryonic development
-
van den Hurk J.A., et al. L1 retrotransposition can occur early in human embryonic development. Hum. Mol. Genet. 2007, 16:1587-1592.
-
(2007)
Hum. Mol. Genet.
, vol.16
, pp. 1587-1592
-
-
van den Hurk, J.A.1
-
14
-
-
69349096044
-
L1 retrotransposition in human neural progenitor cells
-
Coufal N.G., et al. L1 retrotransposition in human neural progenitor cells. Nature 2009, 460:1127-1131.
-
(2009)
Nature
, vol.460
, pp. 1127-1131
-
-
Coufal, N.G.1
-
15
-
-
69449086642
-
Wnt-mediated activation of NeuroD1 and retro-elements during adult neurogenesis
-
Kuwabara T., et al. Wnt-mediated activation of NeuroD1 and retro-elements during adult neurogenesis. Nat. Neurosci. 2009, 12:1097-1105.
-
(2009)
Nat. Neurosci.
, vol.12
, pp. 1097-1105
-
-
Kuwabara, T.1
-
16
-
-
77955271952
-
LINE-1 retrotransposons: mediators of somatic variation in neuronal genomes?
-
Singer T., et al. LINE-1 retrotransposons: mediators of somatic variation in neuronal genomes?. Trends Neurosci. 2010, 33:345-354.
-
(2010)
Trends Neurosci.
, vol.33
, pp. 345-354
-
-
Singer, T.1
-
17
-
-
70349318211
-
The impact of retrotransposons on human genome evolution
-
Cordaux R., Batzer M.A. The impact of retrotransposons on human genome evolution. Nat. Rev. Genet. 2009, 10:691-703.
-
(2009)
Nat. Rev. Genet.
, vol.10
, pp. 691-703
-
-
Cordaux, R.1
Batzer, M.A.2
-
18
-
-
78751550533
-
Epigenetic control of retrotransposon expression in human embryonic stem cells
-
Macia A., et al. Epigenetic control of retrotransposon expression in human embryonic stem cells. Mol. Cell. Biol. 2011, 31:300-316.
-
(2011)
Mol. Cell. Biol.
, vol.31
, pp. 300-316
-
-
Macia, A.1
-
19
-
-
0041353551
-
LINE-mediated retrotransposition of marked Alu sequences
-
Dewannieux M., et al. LINE-mediated retrotransposition of marked Alu sequences. Nat. Genet. 2003, 35:41-48.
-
(2003)
Nat. Genet.
, vol.35
, pp. 41-48
-
-
Dewannieux, M.1
-
20
-
-
44349103084
-
Drosophila endogenous small RNAs bind to Argonaute 2 in somatic cells
-
Kawamura Y., et al. Drosophila endogenous small RNAs bind to Argonaute 2 in somatic cells. Nature 2008, 453:793-797.
-
(2008)
Nature
, vol.453
, pp. 793-797
-
-
Kawamura, Y.1
-
21
-
-
78549247463
-
L1 retrotransposition in neurons is modulated by MeCP2
-
Muotri A.R., et al. L1 retrotransposition in neurons is modulated by MeCP2. Nature 2010, 468:443-446.
-
(2010)
Nature
, vol.468
, pp. 443-446
-
-
Muotri, A.R.1
-
22
-
-
42149156593
-
DNA instability in postmitotic neurons
-
Gonitel R., et al. DNA instability in postmitotic neurons. Proc. Natl. Acad. Sci. U.S.A. 2008, 105:3467-3472.
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 3467-3472
-
-
Gonitel, R.1
-
23
-
-
0032708840
-
Msh2 deficiency prevents in vivo somatic instability of the CAG repeat in Huntington disease transgenic mice
-
Manley K., et al. Msh2 deficiency prevents in vivo somatic instability of the CAG repeat in Huntington disease transgenic mice. Nat. Genet. 1999, 23:471-473.
-
(1999)
Nat. Genet.
, vol.23
, pp. 471-473
-
-
Manley, K.1
-
24
-
-
0029101616
-
Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer
-
de Wind N., et al. Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer. Cell 1995, 82:321-330.
-
(1995)
Cell
, vol.82
, pp. 321-330
-
-
de Wind, N.1
-
25
-
-
84934874465
-
Nonhomologous DNA end joining (NHEJ) and chromosomal translocations in humans
-
Lieber M.R., et al. Nonhomologous DNA end joining (NHEJ) and chromosomal translocations in humans. Subcell. Biochem. 2010, 50:279-296.
-
(2010)
Subcell. Biochem.
, vol.50
, pp. 279-296
-
-
Lieber, M.R.1
-
26
-
-
67651098662
-
Mechanisms of change in gene copy number
-
Hastings P.J., et al. Mechanisms of change in gene copy number. Nat. Rev. Genet. 2009, 10:551-564.
-
(2009)
Nat. Rev. Genet.
, vol.10
, pp. 551-564
-
-
Hastings, P.J.1
-
27
-
-
0022559757
-
Regulation of genome rearrangement events during lymphocyte differentiation
-
Alt F.W., et al. Regulation of genome rearrangement events during lymphocyte differentiation. Immunol. Rev. 1986, 89:5-30.
-
(1986)
Immunol. Rev.
, vol.89
, pp. 5-30
-
-
Alt, F.W.1
-
28
-
-
36949037544
-
V(D)J and immunoglobulin class switch recombinations: a paradigm to study the regulation of DNA end-joining
-
Soulas-Sprauel P., et al. V(D)J and immunoglobulin class switch recombinations: a paradigm to study the regulation of DNA end-joining. Oncogene 2007, 26:7780-7791.
-
(2007)
Oncogene
, vol.26
, pp. 7780-7791
-
-
Soulas-Sprauel, P.1
-
29
-
-
65249145203
-
Mechanics of T cell receptor gene rearrangement
-
Krangel M.S. Mechanics of T cell receptor gene rearrangement. Curr. Opin. Immunol. 2009, 21:133-139.
-
(2009)
Curr. Opin. Immunol.
, vol.21
, pp. 133-139
-
-
Krangel, M.S.1
-
30
-
-
4344680935
-
Human chromosomes with shorter telomeres and large heterochromatin regions have a higher frequency of acquired somatic cell aneuploidy
-
Leach N.T., et al. Human chromosomes with shorter telomeres and large heterochromatin regions have a higher frequency of acquired somatic cell aneuploidy. Mech. Ageing Dev. 2004, 125:563-573.
-
(2004)
Mech. Ageing Dev.
, vol.125
, pp. 563-573
-
-
Leach, N.T.1
-
31
-
-
0042697343
-
The evolution of transcriptional regulation in eukaryotes
-
Wray G.A., et al. The evolution of transcriptional regulation in eukaryotes. Mol. Biol. Evol. 2003, 20:1377-1419.
-
(2003)
Mol. Biol. Evol.
, vol.20
, pp. 1377-1419
-
-
Wray, G.A.1
-
32
-
-
34347354302
-
Mutational and selective effects on copy-number variants in the human genome
-
Cooper G.M., et al. Mutational and selective effects on copy-number variants in the human genome. Nat. Genet. 2007, 39:S22-29.
-
(2007)
Nat. Genet.
, vol.39
-
-
Cooper, G.M.1
-
33
-
-
0038045576
-
Alteration of gene expression by chromosome loss in the postnatal mouse brain
-
Kaushal D., et al. Alteration of gene expression by chromosome loss in the postnatal mouse brain. J. Neurosci. 2003, 23:5599-5606.
-
(2003)
J. Neurosci.
, vol.23
, pp. 5599-5606
-
-
Kaushal, D.1
-
34
-
-
0028859379
-
Somatic intragenic recombination within the mutated locus BLM can correct the high sister-chromatid exchange phenotype of Bloom syndrome cells
-
Ellis N.A., et al. Somatic intragenic recombination within the mutated locus BLM can correct the high sister-chromatid exchange phenotype of Bloom syndrome cells. Am. J. Hum. Genet. 1995, 57:1019-1027.
-
(1995)
Am. J. Hum. Genet.
, vol.57
, pp. 1019-1027
-
-
Ellis, N.A.1
-
35
-
-
0028146998
-
Self-induced correction of the genetic defect in tyrosinemia type I
-
Kvittingen E.A., et al. Self-induced correction of the genetic defect in tyrosinemia type I. J. Clin. Invest. 1994, 94:1657-1661.
-
(1994)
J. Clin. Invest.
, vol.94
, pp. 1657-1661
-
-
Kvittingen, E.A.1
-
36
-
-
0036464720
-
Adenosine deaminase deficiency with mosaicism for a " second-site suppressor" of a splicing mutation: decline in revertant T lymphocytes during enzyme replacement therapy
-
Arredondo-Vega F.X., et al. Adenosine deaminase deficiency with mosaicism for a " second-site suppressor" of a splicing mutation: decline in revertant T lymphocytes during enzyme replacement therapy. Blood 2002, 99:1005-1013.
-
(2002)
Blood
, vol.99
, pp. 1005-1013
-
-
Arredondo-Vega, F.X.1
-
37
-
-
0035902552
-
Somatic mosaicism in Wiskott-Aldrich syndrome suggests in vivo reversion by a DNA slippage mechanism
-
Wada T., et al. Somatic mosaicism in Wiskott-Aldrich syndrome suggests in vivo reversion by a DNA slippage mechanism. Proc. Natl. Acad. Sci. U.S.A. 2001, 98:8697-8702.
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 8697-8702
-
-
Wada, T.1
-
38
-
-
0035226655
-
Retrotransposon insertions in germ cells and somatic cells
-
discussion 313-304, 317-329
-
Kazazian H.H. Retrotransposon insertions in germ cells and somatic cells. Dev. Biol. (Basel) 2001, 106:307-313. discussion 313-304, 317-329.
-
(2001)
Dev. Biol. (Basel)
, vol.106
, pp. 307-313
-
-
Kazazian, H.H.1
-
39
-
-
3042810192
-
Chemically induced increases and decreases in the rate of expansion of a CAG*CTG triplet repeat
-
Gomes-Pereira M., Monckton D.G. Chemically induced increases and decreases in the rate of expansion of a CAG*CTG triplet repeat. Nucleic Acids Res. 2004, 32:2865-2872.
-
(2004)
Nucleic Acids Res.
, vol.32
, pp. 2865-2872
-
-
Gomes-Pereira, M.1
Monckton, D.G.2
-
41
-
-
79951497419
-
The genomic complexity of primary human prostate cancer
-
Berger M.F., et al. The genomic complexity of primary human prostate cancer. Nature 2011, 470:214-220.
-
(2011)
Nature
, vol.470
, pp. 214-220
-
-
Berger, M.F.1
-
43
-
-
33845895536
-
The frequency of translational misreading errors in E. coli is largely determined by tRNA competition
-
Kramer E.B., Farabaugh P.J. The frequency of translational misreading errors in E. coli is largely determined by tRNA competition. RNA 2007, 13:87-96.
-
(2007)
RNA
, vol.13
, pp. 87-96
-
-
Kramer, E.B.1
Farabaugh, P.J.2
-
44
-
-
0036180155
-
Chromosomal mosaicism throughout human preimplantation development in vitro: incidence, type, and relevance to embryo outcome
-
Bielanska M., et al. Chromosomal mosaicism throughout human preimplantation development in vitro: incidence, type, and relevance to embryo outcome. Hum. Reprod. 2002, 17:413-419.
-
(2002)
Hum. Reprod.
, vol.17
, pp. 413-419
-
-
Bielanska, M.1
-
45
-
-
12444311753
-
Detailed FISH analysis of day 5 human embryos reveals the mechanisms leading to mosaic aneuploidy
-
Daphnis D.D., et al. Detailed FISH analysis of day 5 human embryos reveals the mechanisms leading to mosaic aneuploidy. Hum. Reprod. 2005, 20:129-137.
-
(2005)
Hum. Reprod.
, vol.20
, pp. 129-137
-
-
Daphnis, D.D.1
-
46
-
-
66749169417
-
Chromosome instability is common in human cleavage-stage embryos
-
Vanneste E., et al. Chromosome instability is common in human cleavage-stage embryos. Nat. Med. 2009, 15:577-583.
-
(2009)
Nat. Med.
, vol.15
, pp. 577-583
-
-
Vanneste, E.1
-
47
-
-
0020606517
-
Chromosomal mosaicism confined to the placenta in human conceptions
-
Kalousek D.K., Dill F.J. Chromosomal mosaicism confined to the placenta in human conceptions. Science 1983, 221:665-667.
-
(1983)
Science
, vol.221
, pp. 665-667
-
-
Kalousek, D.K.1
Dill, F.J.2
-
48
-
-
79251486355
-
Cell competition
-
Baker N.E. Cell competition. Curr. Biol. 2011, 21:R11-15.
-
(2011)
Curr. Biol.
, vol.21
-
-
Baker, N.E.1
-
49
-
-
48649094457
-
Cell competition and its possible relation to cancer
-
Baker N.E., Li W. Cell competition and its possible relation to cancer. Cancer Res. 2008, 68:5505-5507.
-
(2008)
Cancer Res.
, vol.68
, pp. 5505-5507
-
-
Baker, N.E.1
Li, W.2
-
50
-
-
77955971943
-
A tumor-suppressing mechanism in Drosophila involving cell competition and the Hippo pathway
-
Menendez J., et al. A tumor-suppressing mechanism in Drosophila involving cell competition and the Hippo pathway. Proc. Natl. Acad. Sci. U.S.A. 2010, 107:14651-14656.
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 14651-14656
-
-
Menendez, J.1
-
51
-
-
38549147654
-
Is cell competition relevant to cancer?
-
Moreno E. Is cell competition relevant to cancer?. Nat. Rev. Cancer 2008, 8:141-147.
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 141-147
-
-
Moreno, E.1
-
52
-
-
40849109768
-
Phenotypically concordant and discordant monozygotic twins display different DNA copy-number-variation profiles
-
Bruder C.E., et al. Phenotypically concordant and discordant monozygotic twins display different DNA copy-number-variation profiles. Am. J. Hum. Genet. 2008, 82:763-771.
-
(2008)
Am. J. Hum. Genet.
, vol.82
, pp. 763-771
-
-
Bruder, C.E.1
-
53
-
-
23044514669
-
Epigenetic differences arise during the lifetime of monozygotic twins
-
Fraga M.F., et al. Epigenetic differences arise during the lifetime of monozygotic twins. Proc. Natl. Acad. Sci. U.S.A. 2005, 102:10604-10609.
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 10604-10609
-
-
Fraga, M.F.1
-
54
-
-
78349249402
-
Somatic mosaicism for chromosome X and Y aneuploidies in monozygotic twins heterozygous for sickle cell disease mutation
-
Razzaghian H.R., et al. Somatic mosaicism for chromosome X and Y aneuploidies in monozygotic twins heterozygous for sickle cell disease mutation. Am. J. Med. Genet. A 2010, 152A:2595-2598.
-
(2010)
Am. J. Med. Genet. A
, vol.152 A
, pp. 2595-2598
-
-
Razzaghian, H.R.1
-
55
-
-
77955066602
-
Mosaic uniparental disomies and aneuploidies as large structural variants of the human genome
-
Rodriguez-Santiago B., et al. Mosaic uniparental disomies and aneuploidies as large structural variants of the human genome. Am. J. Hum. Genet. 2010, 87:129-138.
-
(2010)
Am. J. Hum. Genet.
, vol.87
, pp. 129-138
-
-
Rodriguez-Santiago, B.1
-
56
-
-
20544466648
-
Somatic mosaicism in neuronal precursor cells mediated by L1 retrotransposition
-
Muotri A.R., et al. Somatic mosaicism in neuronal precursor cells mediated by L1 retrotransposition. Nature 2005, 435:903-910.
-
(2005)
Nature
, vol.435
, pp. 903-910
-
-
Muotri, A.R.1
-
57
-
-
37049012350
-
Aneuploidy and confined chromosomal mosaicism in the developing human brain
-
Yurov Y.B., et al. Aneuploidy and confined chromosomal mosaicism in the developing human brain. PLoS ONE 2007, 2:e558.
-
(2007)
PLoS ONE
, vol.2
-
-
Yurov, Y.B.1
-
58
-
-
14844328676
-
The variation of aneuploidy frequency in the developing and adult human brain revealed by an interphase FISH study
-
Yurov Y.B., et al. The variation of aneuploidy frequency in the developing and adult human brain revealed by an interphase FISH study. J. Histochem. Cytochem. 2005, 53:385-390.
-
(2005)
J. Histochem. Cytochem.
, vol.53
, pp. 385-390
-
-
Yurov, Y.B.1
-
59
-
-
20044379205
-
Constitutional aneuploidy in the normal human brain
-
Rehen S.K., et al. Constitutional aneuploidy in the normal human brain. J. Neurosci. 2005, 25:2176-2180.
-
(2005)
J. Neurosci.
, vol.25
, pp. 2176-2180
-
-
Rehen, S.K.1
-
60
-
-
51549095601
-
Somatic mosaicism for copy number variation in differentiated human tissues
-
Piotrowski A., et al. Somatic mosaicism for copy number variation in differentiated human tissues. Hum. Mutat. 2008, 29:1118-1124.
-
(2008)
Hum. Mutat.
, vol.29
, pp. 1118-1124
-
-
Piotrowski, A.1
-
61
-
-
0033515256
-
-
Centers for Disease Control and Prevention (CDC) Ten great public health achievements - United States, 1900-1999. MMWR Morb. Mortal Wkly. Rep. 48
-
Centers for Disease Control and Prevention (CDC) (1999) Ten great public health achievements - United States, 1900-1999. MMWR Morb. Mortal Wkly. Rep. 48, 241-243.
-
(1999)
, pp. 241-243
-
-
-
62
-
-
0023572133
-
A search for DNA alterations in the aging mammalian genome: an experimental strategy
-
Vijg J., Uitterlinden A.G. A search for DNA alterations in the aging mammalian genome: an experimental strategy. Mech. Ageing Dev. 1987, 41:47-63.
-
(1987)
Mech. Ageing Dev.
, vol.41
, pp. 47-63
-
-
Vijg, J.1
Uitterlinden, A.G.2
-
63
-
-
0036851242
-
Genome dynamics in aging mice
-
Dolle M.E., Vijg J. Genome dynamics in aging mice. Genome Res. 2002, 12:1732-1738.
-
(2002)
Genome Res.
, vol.12
, pp. 1732-1738
-
-
Dolle, M.E.1
Vijg, J.2
-
64
-
-
0032085368
-
Accelerated accumulation of somatic mutations in the senescence-accelerated mouse
-
Odagiri Y., et al. Accelerated accumulation of somatic mutations in the senescence-accelerated mouse. Nat. Genet. 1998, 19:116-117.
-
(1998)
Nat. Genet.
, vol.19
, pp. 116-117
-
-
Odagiri, Y.1
-
65
-
-
0035964315
-
Does oxidative damage to DNA increase with age?
-
Hamilton M.L., et al. Does oxidative damage to DNA increase with age?. Proc. Natl. Acad. Sci. U.S.A. 2001, 98:10469-10474.
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 10469-10474
-
-
Hamilton, M.L.1
-
67
-
-
27844596799
-
Neuronal expression of p53 dominant-negative proteins in adult Drosophila melanogaster extends life span
-
Bauer J.H., et al. Neuronal expression of p53 dominant-negative proteins in adult Drosophila melanogaster extends life span. Curr. Biol. 2005, 15:2063-2068.
-
(2005)
Curr. Biol.
, vol.15
, pp. 2063-2068
-
-
Bauer, J.H.1
-
68
-
-
34247115941
-
Genome dynamics and transcriptional deregulation in aging
-
Busuttil R., et al. Genome dynamics and transcriptional deregulation in aging. Neuroscience 2007, 145:1341-1347.
-
(2007)
Neuroscience
, vol.145
, pp. 1341-1347
-
-
Busuttil, R.1
-
69
-
-
33846703426
-
Hallmarks of telomeres in ageing research
-
Shay J.W., Wright W.E. Hallmarks of telomeres in ageing research. J. Pathol. 2007, 211:114-123.
-
(2007)
J. Pathol.
, vol.211
, pp. 114-123
-
-
Shay, J.W.1
Wright, W.E.2
-
70
-
-
56949088692
-
Reduced telomere length variation in healthy oldest old
-
Halaschek-Wiener J., et al. Reduced telomere length variation in healthy oldest old. Mech. Ageing Dev. 2008, 129:638-641.
-
(2008)
Mech. Ageing Dev.
, vol.129
, pp. 638-641
-
-
Halaschek-Wiener, J.1
-
71
-
-
0037167855
-
Stochastic and genetic factors influence tissue-specific decline in ageing C. elegans
-
Herndon L.A., et al. Stochastic and genetic factors influence tissue-specific decline in ageing C. elegans. Nature 2002, 419:808-814.
-
(2002)
Nature
, vol.419
, pp. 808-814
-
-
Herndon, L.A.1
-
72
-
-
0033901422
-
MtDNA substitution rate and segregation of heteroplasmy in coding and noncoding regions
-
Cavelier L., et al. MtDNA substitution rate and segregation of heteroplasmy in coding and noncoding regions. Hum. Genet. 2000, 107:45-50.
-
(2000)
Hum. Genet.
, vol.107
, pp. 45-50
-
-
Cavelier, L.1
-
73
-
-
17744393686
-
Mitochondrial DNA mutations in human disease
-
Taylor R.W., Turnbull D.M. Mitochondrial DNA mutations in human disease. Nat. Rev. Genet. 2005, 6:389-402.
-
(2005)
Nat. Rev. Genet.
, vol.6
, pp. 389-402
-
-
Taylor, R.W.1
Turnbull, D.M.2
-
74
-
-
77950083955
-
Heteroplasmic mitochondrial DNA mutations in normal and tumour cells
-
He Y., et al. Heteroplasmic mitochondrial DNA mutations in normal and tumour cells. Nature 2010, 464:610-614.
-
(2010)
Nature
, vol.464
, pp. 610-614
-
-
He, Y.1
-
75
-
-
77955562856
-
Detecting heteroplasmy from high-throughput sequencing of complete human mitochondrial DNA genomes
-
Li M., et al. Detecting heteroplasmy from high-throughput sequencing of complete human mitochondrial DNA genomes. Am. J. Hum. Genet. 2010, 87:237-249.
-
(2010)
Am. J. Hum. Genet.
, vol.87
, pp. 237-249
-
-
Li, M.1
-
76
-
-
18344382135
-
Combined transcriptome and genome analysis of single micrometastatic cells
-
Klein C.A., et al. Combined transcriptome and genome analysis of single micrometastatic cells. Nat. Biotechnol. 2002, 20:387-392.
-
(2002)
Nat. Biotechnol.
, vol.20
, pp. 387-392
-
-
Klein, C.A.1
-
77
-
-
77954817961
-
Genomic neighbourhood and the regulation of gene expression
-
De S., Babu M.M. Genomic neighbourhood and the regulation of gene expression. Curr. Opin. Cell Biol. 2010, 22:326-333.
-
(2010)
Curr. Opin. Cell Biol.
, vol.22
, pp. 326-333
-
-
De, S.1
Babu, M.M.2
-
78
-
-
0032569851
-
Hsp90 as a capacitor for morphological evolution
-
Rutherford S.L., Lindquist S. Hsp90 as a capacitor for morphological evolution. Nature 1998, 396:336-342.
-
(1998)
Nature
, vol.396
, pp. 336-342
-
-
Rutherford, S.L.1
Lindquist, S.2
-
79
-
-
52949121033
-
Incapacitating the evolutionary capacitor: Hsp90 modulation of disease
-
Yeyati P.L., van Heyningen V. Incapacitating the evolutionary capacitor: Hsp90 modulation of disease. Curr. Opin. Genet. Dev. 2008, 18:264-272.
-
(2008)
Curr. Opin. Genet. Dev.
, vol.18
, pp. 264-272
-
-
Yeyati, P.L.1
van Heyningen, V.2
-
80
-
-
76349117871
-
Hsp90 prevents phenotypic variation by suppressing the mutagenic activity of transposons
-
Specchia V., et al. Hsp90 prevents phenotypic variation by suppressing the mutagenic activity of transposons. Nature 2010, 463:662-665.
-
(2010)
Nature
, vol.463
, pp. 662-665
-
-
Specchia, V.1
-
81
-
-
77951139631
-
Genome remodelling in a basal-like breast cancer metastasis and xenograft
-
Ding L., et al. Genome remodelling in a basal-like breast cancer metastasis and xenograft. Nature 2010, 464:999-1005.
-
(2010)
Nature
, vol.464
, pp. 999-1005
-
-
Ding, L.1
-
82
-
-
77951620282
-
Frequent genetic differences between matched primary and metastatic breast cancer provide an approach to identification of biomarkers for disease progression
-
Poplawski A.B., et al. Frequent genetic differences between matched primary and metastatic breast cancer provide an approach to identification of biomarkers for disease progression. Eur. J. Hum. Genet. 2010, 18:560-568.
-
(2010)
Eur. J. Hum. Genet.
, vol.18
, pp. 560-568
-
-
Poplawski, A.B.1
-
83
-
-
45149112698
-
The look-ahead effect of phenotypic mutations
-
Whitehead D.J., et al. The look-ahead effect of phenotypic mutations. Biol. Direct 2008, 3:18.
-
(2008)
Biol. Direct
, vol.3
, pp. 18
-
-
Whitehead, D.J.1
-
84
-
-
77953886431
-
Genetics of neurodegenerative diseases: insights from high-throughput resequencing
-
Tsuji S. Genetics of neurodegenerative diseases: insights from high-throughput resequencing. Hum. Mol. Genet. 2010, 19:R65-70.
-
(2010)
Hum. Mol. Genet.
, vol.19
-
-
Tsuji, S.1
-
85
-
-
45449126571
-
Mathematical models of cancer stem cells
-
Michor F. Mathematical models of cancer stem cells. J. Clin. Oncol. 2008, 26:2854-2861.
-
(2008)
J. Clin. Oncol.
, vol.26
, pp. 2854-2861
-
-
Michor, F.1
-
86
-
-
77952574849
-
Uncovering the roles of rare variants in common disease through whole-genome sequencing
-
Cirulli E.T., Goldstein D.B. Uncovering the roles of rare variants in common disease through whole-genome sequencing. Nat. Rev. Genet. 2010, 11:415-425.
-
(2010)
Nat. Rev. Genet.
, vol.11
, pp. 415-425
-
-
Cirulli, E.T.1
Goldstein, D.B.2
-
87
-
-
70349956433
-
Finding the missing heritability of complex diseases
-
Manolio T.A., et al. Finding the missing heritability of complex diseases. Nature 2009, 461:747-753.
-
(2009)
Nature
, vol.461
, pp. 747-753
-
-
Manolio, T.A.1
-
88
-
-
62549085618
-
Human genetic variation and its contribution to complex traits
-
Frazer K.A., et al. Human genetic variation and its contribution to complex traits. Nat. Rev. Genet. 2009, 10:241-251.
-
(2009)
Nat. Rev. Genet.
, vol.10
, pp. 241-251
-
-
Frazer, K.A.1
|