Single-Cell, Genome-wide Sequencing Identifies Clonal Somatic Copy-Number Variation in the Human Brain

Cell Reports

Volumn 8, Issue 5, 2014, Pages 1280-1289

  Cai, Xuyu ^a,b,c   Evrony, Gilad D ^a,b,c   Lehmann, Hillel S ^a,b,c   Elhosary, Princess C ^a,b,c   Mehta, Bhaven K ^a,b,c   Poduri, Annapurna ^a,b,c,d   Walsh, Christopher A ^a,b,c  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^d BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALEXANDER DISEASE; ANEUPLOIDY; ARTICLE; BRAIN DYSFUNCTION; BRAIN NERVE CELL; CHROMOSOME 15Q; CHROMOSOME 18; CHROMOSOME 1Q; CHROMOSOME ANALYSIS; CLONAL VARIATION; CONTROLLED STUDY; COPY NUMBER VARIATION; FETUS; GENE SEQUENCE; GERM LINE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOREACTIVITY; LYMPHOBLAST; NERVE CELL DIFFERENTIATION; PATHOGENESIS; SINGLE CELL ANALYSIS; SOMATIC MUTATION; TRISOMY; BRAIN; CHROMOSOME 1; CYTOLOGY; DNA SEQUENCE; GENETICS; HUMAN GENOME; LYMPHOCYTE; METABOLISM; NERVE CELL; TETRASOMY;

BRAIN; CHROMOSOMES, HUMAN, PAIR 1; CHROMOSOMES, HUMAN, PAIR 18; DNA COPY NUMBER VARIATIONS; GENOME, HUMAN; HEMIMEGALENCEPHALY; HUMANS; LYMPHOCYTES; NEURONS; SEQUENCE ANALYSIS, DNA; SINGLE-CELL ANALYSIS; TETRASOMY; TRISOMY;

EID: 84922584195     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2014.07.043     Document Type: Article

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