메뉴 건너뛰기




Volumn , Issue , 2014, Pages 73-113

EIF4E and its binding proteins

Author keywords

Cancer; eIF4E; eIF4E Binding Protein (4E BP); Mitogen activated protein kinase (MAPK) pathway; mTOR pathway; Proto oncogene; Regulation of translation; Translation initiation; Tumor suppressor; Tumorigenesis

Indexed keywords


EID: 84930921990     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-94-017-9078-9_4     Document Type: Chapter
Times cited : (4)

References (259)
  • 3
    • 0030640902 scopus 로고    scopus 로고
    • TOP genes: A translationally controlled class of genes including those coding for ribosomal proteins
    • Amaldi F, Pierandrei-Amaldi P (1997) TOP genes: a translationally controlled class of genes including those coding for ribosomal proteins. Prog Mol Subcell Biol 18:1-17
    • (1997) Prog Mol Subcell Biol , vol.18 , pp. 1-17
    • Amaldi, F.1    Pierandrei-Amaldi, P.2
  • 5
    • 0033828440 scopus 로고    scopus 로고
    • Eukaryote-specific domains in translation initiation factors: Implications for translation regulation and evolution of the translation system
    • Aravind L, Koonin EV (2000) Eukaryote-specific domains in translation initiation factors: implications for translation regulation and evolution of the translation system. Genome Res 10:1172-1184
    • (2000) Genome Res , vol.10 , pp. 1172-1184
    • Aravind, L.1    Koonin, E.V.2
  • 6
    • 60149100371 scopus 로고    scopus 로고
    • Activation of host translational control pathways by a viral developmental switch
    • Arias C, Walsh D, Harbell J, Wilson AC, Mohr I (2009) Activation of host translational control pathways by a viral developmental switch. PLoS Pathog 5:e1000334
    • (2009) PLoS Pathog , vol.5 , pp. e1000334
    • Arias, C.1    Walsh, D.2    Harbell, J.3    Wilson, A.C.4    Mohr, I.5
  • 8
    • 28844448182 scopus 로고    scopus 로고
    • Oncogenic PI3K deregulates transcription and translation
    • Bader AG, Kang S, Zhao L, Vogt PK (2005) Oncogenic PI3K deregulates transcription and translation. Nat Rev Cancer 5:921-929
    • (2005) Nat Rev Cancer , vol.5 , pp. 921-929
    • Bader, A.G.1    Kang, S.2    Zhao, L.3    Vogt, P.K.4
  • 10
    • 77951811915 scopus 로고    scopus 로고
    • Distinct high resolution genome profiles of early onset and late onset colorectal cancer integrated with gene expression data identify candidate susceptibility loci
    • Berg M, Agesen TH, Thiis-Evensen E, Merok MA, Teixeira MR, Vatn MH, Nesbakken A, Skotheim RI, Lothe RA (2010) Distinct high resolution genome profiles of early onset and late onset colorectal cancer integrated with gene expression data identify candidate susceptibility loci. Mol Cancer 9:100
    • (2010) Mol Cancer , vol.9 , pp. 100
    • Berg, M.1    Agesen, T.H.2    Thiis-Evensen, E.3    Merok, M.A.4    Teixeira, M.R.5    Vatn, M.H.6    Nesbakken, A.7    Skotheim, R.I.8    Lothe, R.A.9
  • 12
    • 34547890999 scopus 로고    scopus 로고
    • Tuberous sclerosis complex proteins 1 and 2 control serum-dependent translation in a TOPdependent and-independent manner
    • Bilanges B, Argonza-Barrett R, Kolesnichenko M, Skinner C, Nair M, Chen M, Stokoe D (2007) Tuberous sclerosis complex proteins 1 and 2 control serum-dependent translation in a TOPdependent and-independent manner. Mol Cell Biol 27:5746-5764
    • (2007) Mol Cell Biol , vol.27 , pp. 5746-5764
    • Bilanges, B.1    Argonza-Barrett, R.2    Kolesnichenko, M.3    Skinner, C.4    Nair, M.5    Chen, M.6    Stokoe, D.7
  • 14
    • 79955637310 scopus 로고    scopus 로고
    • The biological and therapeutic relevance of mRNA translation in cancer
    • Blagden SP, Willis AE (2011) The biological and therapeutic relevance of mRNA translation in cancer. Nat Rev Clin Oncol 8:280-291
    • (2011) Nat Rev Clin Oncol , vol.8 , pp. 280-291
    • Blagden, S.P.1    Willis, A.E.2
  • 15
    • 52049088725 scopus 로고    scopus 로고
    • The Mnks: MAP kinase-interacting kinases (MAP kinase signal-integrating kinases)
    • Buxade M, Parra-Palau JL, Proud CG (2008) The Mnks: MAP kinase-interacting kinases (MAP kinase signal-integrating kinases) Front Biosci 13:5359-5373
    • (2008) Front Biosci , vol.13 , pp. 5359-5373
    • Buxade, M.1    Parra-Palau, J.L.2    Proud, C.G.3
  • 17
    • 33750089285 scopus 로고    scopus 로고
    • Phosphorylated 4E binding protein 1: A hallmark of cell signaling that correlates with survival in ovarian cancer
    • Castellvi J, Garcia A, Rojo F, Ruiz-Marcellan C, Gil A, Baselga J, Ramon y Cajal S (2006) Phosphorylated 4E binding protein 1: a hallmark of cell signaling that correlates with survival in ovarian cancer. Cancer 107:1801-1811
    • (2006) Cancer , vol.107 , pp. 1801-1811
    • Castellvi, J.1    Garcia, A.2    Rojo, F.3    Ruiz-Marcellan, C.4    Gil, A.5    Baselga, J.6    Ramon Cajal, S.7
  • 18
    • 84870542434 scopus 로고    scopus 로고
    • EIF4E-binding protein regulation of mRNAs with differential 5?-UTR secondary structure: A polyelectrostatic model for a component of protein-mRNA interactions
    • Cawley A, Warwicker J (2012) eIF4E-binding protein regulation of mRNAs with differential 5?-UTR secondary structure: a polyelectrostatic model for a component of protein-mRNA interactions. Nucleic Acids Research 40:7666-7675
    • (2012) Nucleic Acids Research , vol.40 , pp. 7666-7675
    • Cawley, A.1    Warwicker, J.2
  • 19
    • 79953049807 scopus 로고    scopus 로고
    • Rapamycin reverses splenomegaly and inhibits tumor development in a transgenic model of Epstein-Barr virus-related Burkitt's lymphoma
    • Cen O, Longnecker R (2011) Rapamycin reverses splenomegaly and inhibits tumor development in a transgenic model of Epstein-Barr virus-related Burkitt's lymphoma. Mol Cancer Ther 10:679-686
    • (2011) Mol Cancer Ther , vol.10 , pp. 679-686
    • Cen, O.1    Longnecker, R.2
  • 20
    • 34347369749 scopus 로고    scopus 로고
    • Notch signals positively regulate activity of the mTOR pathway in T-cell acute lymphoblastic leukemia
    • Chan SM, Weng AP, Tibshirani R, Aster JC, Utz PJ (2007) Notch signals positively regulate activity of the mTOR pathway in T-cell acute lymphoblastic leukemia. Blood 110:278-286
    • (2007) Blood , vol.110 , pp. 278-286
    • Chan, S.M.1    Weng, A.P.2    Tibshirani, R.3    Aster, J.C.4    Utz, P.J.5
  • 22
    • 1842863109 scopus 로고    scopus 로고
    • Expression of eukaryotic initiation factor 4E in gastric adenocarcinoma and its association with clinical outcome
    • Chen CN, Hsieh FJ, Cheng YM, Lee PH, Chang KJ (2004) Expression of eukaryotic initiation factor 4E in gastric adenocarcinoma and its association with clinical outcome. J Surg Oncol 86:22-27
    • (2004) J Surg Oncol , vol.86 , pp. 22-27
    • Chen, C.N.1    Hsieh, F.J.2    Cheng, Y.M.3    Lee, P.H.4    Chang, K.J.5
  • 23
    • 18844397041 scopus 로고    scopus 로고
    • A new paradigm for translational control: Inhibition via 5?-3? mRNA tethering by Bicoid and the eIF4E cognate 4EHP
    • Cho PF, Poulin F, Cho-Park YA, Cho-Park IB, Chicoine JD, Lasko P, Sonenberg N (2005) A new paradigm for translational control: inhibition via 5?-3? mRNA tethering by Bicoid and the eIF4E cognate 4EHP. Cell 121:411-423
    • (2005) Cell , vol.121 , pp. 411-423
    • Cho, P.F.1    Poulin, F.2    Cho-Park, Y.A.3    Cho-Park, I.B.4    Chicoine, J.D.5    Lasko, P.6    Sonenberg, N.7
  • 24
    • 11244309014 scopus 로고    scopus 로고
    • Proteolysis: From the lysosome to ubiquitin and the proteasome
    • Ciechanover A (2005) Proteolysis: from the lysosome to ubiquitin and the proteasome. Nat Rev Mol Cell Biol 6:79-87
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 79-87
    • Ciechanover, A.1
  • 28
    • 0033988498 scopus 로고    scopus 로고
    • Eukaryotic initiation factor-4E in superficial and muscle invasive bladder cancer and its correlation with vascular endothelial growth factor expression and tumour progression
    • Crew JP, Fuggle S, Bicknell R, Cranston DW, de Benedetti A, Harris AL (2000) Eukaryotic initiation factor-4E in superficial and muscle invasive bladder cancer and its correlation with vascular endothelial growth factor expression and tumour progression. Br J Cancer 82:161-166
    • (2000) Br J Cancer , vol.82 , pp. 161-166
    • Crew, J.P.1    Fuggle, S.2    Bicknell, R.3    Cranston, D.W.4    De Benedetti, A.5    Harris, A.L.6
  • 31
    • 1542478512 scopus 로고
    • Differential efficiencies of in vitro translation of mouse c-myc transcripts differing in the 5? untranslated region
    • Darveau A, Pelletier J, Sonenberg N (1985) Differential efficiencies of in vitro translation of mouse c-myc transcripts differing in the 5? untranslated region. Proc Natl Acad Sci U S A 82:2315-2319
    • (1985) Proc Natl Acad Sci U S A , vol.82 , pp. 2315-2319
    • Darveau, A.1    Pelletier, J.2    Sonenberg, N.3
  • 32
    • 2342489456 scopus 로고    scopus 로고
    • EIF-4E expression and its role in malignancies and metastases
    • De Benedetti A, Graff JR (2004) eIF-4E expression and its role in malignancies and metastases. Oncogene 23:3189-3199
    • (2004) Oncogene , vol.23 , pp. 3189-3199
    • De Benedetti, A.1    Graff, J.R.2
  • 33
    • 0033044355 scopus 로고    scopus 로고
    • EIF4E expression in tumors: Its possible role in progression of malignancies
    • De Benedetti A, Harris AL (1999) eIF4E expression in tumors: its possible role in progression of malignancies. Int J Biochem Cell Biol 31:59-72
    • (1999) Int J Biochem Cell Biol , vol.31 , pp. 59-72
    • De Benedetti, A.1    Harris, A.L.2
  • 35
    • 58549093201 scopus 로고    scopus 로고
    • Tumor-specific RNAi targeting eIF4E suppresses tumor growth, induces apoptosis and enhances cisplatin cytotoxicity in human breast carcinoma cells
    • Dong K, Wang R, Wang X, Lin F, Shen JJ, Gao P, Zhang HZ (2009) Tumor-specific RNAi targeting eIF4E suppresses tumor growth, induces apoptosis and enhances cisplatin cytotoxicity in human breast carcinoma cells. Breast Cancer Res Treat 113:443-456
    • (2009) Breast Cancer Res Treat , vol.113 , pp. 443-456
    • Dong, K.1    Wang, R.2    Wang, X.3    Lin, F.4    Shen, J.J.5    Gao, P.6    Zhang, H.Z.7
  • 37
    • 0023124676 scopus 로고
    • Regulated phosphorylation and low abundance of HeLa cell initiation factor eIF-4F suggest a role in translational control
    • Duncan R, Milburn SC, Hershey JW (1987) Regulated phosphorylation and low abundance of HeLa cell initiation factor eIF-4F suggest a role in translational control. Heat shock effects on eIF-4F. J Biol Chem 262:380-388
    • (1987) Heat Shock Effects on eIF-4F. J Biol Chem , vol.262 , pp. 380-388
    • Duncan, R.1    Milburn, S.C.2    Hershey, J.W.3
  • 38
    • 0020356106 scopus 로고
    • Inhibition of HeLa cell protein synthesis following poliovirus infection correlates with the proteolysis of a 220,000-dalton polypeptide associated with eucaryotic initiation factor 3 and a cap binding protein complex
    • Etchison D, Milburn SC, Edery I, Sonenberg N, Hershey JW (1982) Inhibition of HeLa cell protein synthesis following poliovirus infection correlates with the proteolysis of a 220,000-dalton polypeptide associated with eucaryotic initiation factor 3 and a cap binding protein complex. J Biol Chem 257:14806-14810
    • (1982) J Biol Chem , vol.257 , pp. 14806-14810
    • Etchison, D.1    Milburn, S.C.2    Edery, I.3    Sonenberg, N.4    Hershey, J.W.5
  • 39
    • 67650999750 scopus 로고    scopus 로고
    • Regulatory element identification in subsets of transcripts: Comparison and integration of current computational methods
    • Fan D, Bitterman PB, Larsson O (2009a) Regulatory element identification in subsets of transcripts: comparison and integration of current computational methods. RNA 15:1469-1482
    • (2009) RNA , vol.15 , pp. 1469-1482
    • Fan, D.1    Bitterman, P.B.2    Larsson, O.3
  • 40
    • 85046915181 scopus 로고    scopus 로고
    • Phosphorylated eukaryotic translation initiation factor 4 (eIF4E) is elevated in human cancer tissues
    • Fan S, Ramalingam SS, Kauh J, Xu Z, Khuri FR, Sun SY (2009b) Phosphorylated eukaryotic translation initiation factor 4 (eIF4E) is elevated in human cancer tissues. Cancer Biol Ther 8:1463-1469
    • (2009) Cancer Biol Ther , vol.8 , pp. 1463-1469
    • Fan, S.1    Ramalingam, S.S.2    Kauh, J.3    Xu, Z.4    Khuri, F.R.5    Sun, S.Y.6
  • 42
    • 84882291342 scopus 로고    scopus 로고
    • Human eIF4E promotes mRNA restructuring by stimulating eIF4A helicase activity
    • Feoktistova K, Tuvshintogs E, Do A, Fraser CS (2013) Human eIF4E promotes mRNA restructuring by stimulating eIF4A helicase activity. Proc Natl Acad Sci U S A 110:13339-13344
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 13339-13344
    • Feoktistova, K.1    Tuvshintogs, E.2    Do, A.3    Fraser, C.S.4
  • 44
    • 0031821410 scopus 로고    scopus 로고
    • The interaction of eIF4E with 4E-BP1 is an induced fit to a completely disordered protein
    • Fletcher CM, Wagner G (1998) The interaction of eIF4E with 4E-BP1 is an induced fit to a completely disordered protein. Protein Sci 7:1639-1642
    • (1998) Protein Sci , vol.7 , pp. 1639-1642
    • Fletcher, C.M.1    Wagner, G.2
  • 45
    • 84873774168 scopus 로고
    • Growth and metastasis of tumor in organ culture
    • Folkman J, Long DM Jr, Becker FF (1963) Growth and metastasis of tumor in organ culture. Cancer 16:453-467
    • (1963) Cancer , vol.16 , pp. 453-467
    • Folkman, J.1    Long, D.M.2    Becker, F.F.3
  • 51
    • 84856828353 scopus 로고    scopus 로고
    • Hepatitis C virus NS5A binds to the mRNA cap-binding eukaryotic translation initiation 4F (eIF4F) complex and up-regulates host translation initiation machinery through eIF4E-binding protein 1 inactivation
    • George A, Panda S, Kudmulwar D, Chhatbar SP, Nayak SC, Krishnan HH (2012) Hepatitis C virus NS5A binds to the mRNA cap-binding eukaryotic translation initiation 4F (eIF4F) complex and up-regulates host translation initiation machinery through eIF4E-binding protein 1 inactivation. J Biol Chem 287:5042-5058
    • (2012) J Biol Chem , vol.287 , pp. 5042-5058
    • George, A.1    Panda, S.2    Kudmulwar, D.3    Chhatbar, S.P.4    Nayak, S.C.5    Krishnan, H.H.6
  • 55
    • 78049452625 scopus 로고    scopus 로고
    • MAPK signal-integrating kinase controls cap-independent translation and cell type-specific cytotoxicity of an oncolytic poliovirus
    • Goetz C, Everson RG, Zhang LC, Gromeier M (2010) MAPK signal-integrating kinase controls cap-independent translation and cell type-specific cytotoxicity of an oncolytic poliovirus. Mol Ther 18:1937-1946
    • (2010) Mol Ther , vol.18 , pp. 1937-1946
    • Goetz, C.1    Everson, R.G.2    Zhang, L.C.3    Gromeier, M.4
  • 58
    • 0028897627 scopus 로고
    • Reduction of translation initiation factor 4E decreases the malignancy of ras-transformed cloned rat embryo fibroblasts
    • Graff JR, Boghaert ER, De Benedetti A, Tudor DL, Zimmer CC, Chan SK, Zimmer SG (1995) Reduction of translation initiation factor 4E decreases the malignancy of ras-transformed cloned rat embryo fibroblasts. Int J Cancer 60:255-263
    • (1995) Int J Cancer , vol.60 , pp. 255-263
    • Graff, J.R.1    Boghaert, E.R.2    De Benedetti, A.3    Tudor, D.L.4    Zimmer, C.C.5    Chan, S.K.6    Zimmer, S.G.7
  • 64
    • 79952749189 scopus 로고    scopus 로고
    • MAP kinase-interacting kinase 1 regulates SMAD2-dependent TGF-beta signaling pathway in human glioblastoma
    • Grzmil M, Morin P Jr, Lino MM, Merlo A, Frank S, Wang Y, Moncayo G, Hemmings BA (2011) MAP kinase-interacting kinase 1 regulates SMAD2-dependent TGF-beta signaling pathway in human glioblastoma. Cancer Res 71:2392-2402
    • (2011) Cancer Res , vol.71 , pp. 2392-2402
    • Grzmil, M.1    Morin, P.2    Lino, M.M.3    Merlo, A.4    Frank, S.5    Wang, Y.6    Moncayo, G.7    Hemmings, B.A.8
  • 65
    • 0030832026 scopus 로고    scopus 로고
    • EIF4G dramatically enhances the binding of eIF4E to the mRNA 5?-cap structure
    • Haghighat A, Sonenberg N (1997) eIF4G dramatically enhances the binding of eIF4E to the mRNA 5?-cap structure. J Biol Chem 272:21677-21680
    • (1997) J Biol Chem , vol.272 , pp. 21677-21680
    • Haghighat, A.1    Sonenberg, N.2
  • 66
    • 0028786952 scopus 로고
    • Repression of cap-dependent translation by 4E-binding protein 1: Competition with p220 for binding to eukaryotic initiation factor-4E
    • Haghighat A, Mader S, Pause A, Sonenberg N (1995) Repression of cap-dependent translation by 4E-binding protein 1: competition with p220 for binding to eukaryotic initiation factor-4E. EMBO J 14:5701-5709
    • (1995) EMBO J , vol.14 , pp. 5701-5709
    • Haghighat, A.1    Mader, S.2    Pause, A.3    Sonenberg, N.4
  • 67
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA (2000) The hallmarks of cancer. Cell 100:57-70
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 68
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D, Weinberg RA (2011) Hallmarks of cancer: the next generation. Cell 144:646-674
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 69
    • 84885603217 scopus 로고    scopus 로고
    • The eukaryotic translation initiation factor eIF4E is a direct transcriptional target of NF-kappaB and is aberrantly regulated in acute myeloid leukemia
    • Hariri F, Arguello M, Volpon L, Culjkovic-Kraljacic B, Nielsen TH, Hiscott J, Mann KK, Borden KL (2013) The eukaryotic translation initiation factor eIF4E is a direct transcriptional target of NF-kappaB and is aberrantly regulated in acute myeloid leukemia. Leukemia 27:2047-2055
    • (2013) Leukemia , vol.27 , pp. 2047-2055
    • Hariri, F.1    Arguello, M.2    Volpon, L.3    Culjkovic-Kraljacic, B.4    Nielsen, T.H.5    Hiscott, J.6    Mann, K.K.7    Borden, K.L.8
  • 72
    • 84884289188 scopus 로고    scopus 로고
    • Eukaryotic translation initiation factor 4E (eIF4E) expression is associated with breast cancer tumor phenotype and predicts survival after anthracycline chemotherapy treatment
    • Heikkinen T, Korpela T, Fagerholm R, Khan S, Aittomaki K, Heikkila P, Blomqvist C, Carpen O, Nevanlinna H (2013) Eukaryotic translation initiation factor 4E (eIF4E) expression is associated with breast cancer tumor phenotype and predicts survival after anthracycline chemotherapy treatment. Breast Cancer Res Treat 141:79-88
    • (2013) Breast Cancer Res Treat , vol.141 , pp. 79-88
    • Heikkinen, T.1    Korpela, T.2    Fagerholm, R.3    Khan, S.4    Aittomaki, K.5    Heikkila, P.6    Blomqvist, C.7    Carpen, O.8    Nevanlinna, H.9
  • 73
    • 70249117786 scopus 로고    scopus 로고
    • Predictive value of eIF4E reduction after neoadjuvant therapy in breast cancer
    • Hiller DJ, Chu Q, Meschonat C, Panu L, Burton G, Li BD (2009) Predictive value of eIF4E reduction after neoadjuvant therapy in breast cancer. J Surg Res 156:265-269
    • (2009) J Surg Res , vol.156 , pp. 265-269
    • Hiller, D.J.1    Chu, Q.2    Meschonat, C.3    Panu, L.4    Burton, G.5    Li, B.D.6
  • 74
    • 0021932863 scopus 로고
    • Immunological detection of the messenger RNA capbinding protein
    • Hiremath LS, Webb NR, Rhoads RE (1985) Immunological detection of the messenger RNA capbinding protein. J Biol Chem 260:7843-7849
    • (1985) J Biol Chem , vol.260 , pp. 7843-7849
    • Hiremath, L.S.1    Webb, N.R.2    Rhoads, R.E.3
  • 75
    • 55149110561 scopus 로고    scopus 로고
    • A prospective trial on initiation factor 4E (eIF4E) overexpression and cancer recurrence in nodenegative breast cancer
    • Holm N, Byrnes K, Johnson L, Abreo F, Sehon K, Alley J, Meschonat C, Md QC, Li BD (2008) A prospective trial on initiation factor 4E (eIF4E) overexpression and cancer recurrence in nodenegative breast cancer. Ann Surg Oncol 15:3207-3215
    • (2008) Ann Surg Oncol , vol.15 , pp. 3207-3215
    • Holm, N.1    Byrnes, K.2    Johnson, L.3    Abreo, F.4    Sehon, K.5    Alley, J.6    Meschonat, C.7    Md, Q.C.8    Li, B.D.9
  • 77
    • 84863803532 scopus 로고    scopus 로고
    • Targeting Mnks for cancer therapy
    • Hou J, Lam F, Proud C, Wang S (2012) Targeting Mnks for cancer therapy. Oncotarget 3:118-131
    • (2012) Oncotarget , vol.3 , pp. 118-131
    • Hou, J.1    Lam, F.2    Proud, C.3    Wang, S.4
  • 80
    • 79955790331 scopus 로고    scopus 로고
    • MDM2 is overexpressed and regulated by the eukaryotic translation initiation factor 4E (eIF4E) in human squamous cell carcinoma of esophagus
    • Hsu HS, Chen HW, Kao CL, Wu ML, Li AF, Cheng TH (2011) MDM2 is overexpressed and regulated by the eukaryotic translation initiation factor 4E (eIF4E) in human squamous cell carcinoma of esophagus. Ann Surg Oncol 18:1469-1477
    • (2011) Ann Surg Oncol , vol.18 , pp. 1469-1477
    • Hsu, H.S.1    Chen, H.W.2    Kao, C.L.3    Wu, M.L.4    Li, A.F.5    Cheng, T.H.6
  • 81
    • 0033594890 scopus 로고    scopus 로고
    • MRNA cap recognition: Dominant role of enhanced stacking interactions between methylated bases and protein aromatic side chains
    • Hu G, Gershon PD, Hodel AE, Quiocho FA (1999) mRNA cap recognition: dominant role of enhanced stacking interactions between methylated bases and protein aromatic side chains. Proc Natl Acad Sci U S A 96:7149-7154
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 7149-7154
    • Hu, G.1    Gershon, P.D.2    Hodel, A.E.3    Quiocho, F.A.4
  • 82
    • 80053070033 scopus 로고    scopus 로고
    • PI3K-targeted therapy can be evaded by gene amplification along the MYC-eukaryotic translation initiation factor 4E (eIF4E) axis
    • Ilic N, Utermark T, Widlund HR, Roberts TM (2011) PI3K-targeted therapy can be evaded by gene amplification along the MYC-eukaryotic translation initiation factor 4E (eIF4E) axis. Proc Natl Acad Sci U S A 108:E699-E708
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. E699-E708
    • Ilic, N.1    Utermark, T.2    Widlund, H.R.3    Roberts, T.M.4
  • 83
    • 33748153690 scopus 로고    scopus 로고
    • TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth
    • Inoki K, Ouyang H, Zhu T, Lindvall C, Wang Y, Zhang X, Yang Q, Bennett C, Harada Y, Stankunas K et al. (2006) TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth. Cell 126:955-968
    • (2006) Cell , vol.126 , pp. 955-968
    • Inoki, K.1    Ouyang, H.2    Zhu, T.3    Lindvall, C.4    Wang, Y.5    Zhang, X.6    Yang, Q.7    Bennett, C.8    Harada, Y.9    Stankunas, K.10
  • 84
    • 75149196287 scopus 로고    scopus 로고
    • The mechanism of eukaryotic translation initiation and principles of its regulation
    • Jackson RJ, Hellen CU, Pestova TV (2010) The mechanism of eukaryotic translation initiation and principles of its regulation. Nat Rev Mol Cell Biol 11:113-127
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 113-127
    • Jackson, R.J.1    Hellen, C.U.2    Pestova, T.V.3
  • 85
    • 0021111301 scopus 로고
    • Possible involvement of poly(A) in protein synthesis
    • Jacobson A, Favreau M (1983) Possible involvement of poly(A) in protein synthesis. Nucleic Acids Res 11:6353-6368
    • (1983) Nucleic Acids Res , vol.11 , pp. 6353-6368
    • Jacobson, A.1    Favreau, M.2
  • 86
    • 0037086074 scopus 로고    scopus 로고
    • Regulation of matrix metalloproteinase-9 (MMP-9) by translational efficiency in murine prostate carcinoma cells
    • Jiang Y, Muschel RJ (2002) Regulation of matrix metalloproteinase-9 (MMP-9) by translational efficiency in murine prostate carcinoma cells. Cancer Res 62:1910-1914
    • (2002) Cancer Res , vol.62 , pp. 1910-1914
    • Jiang, Y.1    Muschel, R.J.2
  • 87
    • 2942515128 scopus 로고    scopus 로고
    • Expression of constitutively active 4EBP-1 enhances p27Kip1 expression and inhibits proliferation of MCF7 breast cancer cells
    • Jiang H, Coleman J, Miskimins R, Miskimins WK (2003) Expression of constitutively active 4EBP-1 enhances p27Kip1 expression and inhibits proliferation of MCF7 breast cancer cells. Cancer Cell Int 3:2
    • (2003) Cancer Cell Int , vol.3 , pp. 2
    • Jiang, H.1    Coleman, J.2    Miskimins, R.3    Miskimins, W.K.4
  • 88
    • 84901191625 scopus 로고    scopus 로고
    • Repression of microRNA-768-3p by MEK/ERK signalling contributes to enhanced mRNA translation in human melanoma
    • Jiang CC, Croft A, Tseng HY, Guo ST, Jin L, Hersey P, Zhang XD (2014) Repression of microRNA-768-3p by MEK/ERK signalling contributes to enhanced mRNA translation in human melanoma. Oncogene 33:2577-2588
    • (2014) Oncogene , vol.33 , pp. 2577-2588
    • Jiang, C.C.1    Croft, A.2    Tseng, H.Y.3    Guo, S.T.4    Jin, L.5    Hersey, P.6    Zhang, X.D.7
  • 89
    • 49549108896 scopus 로고    scopus 로고
    • Wnt and beyond Wnt: Multiple mechanisms control the transcriptional property of beta-catenin
    • Jin T, George Fantus I, Sun J (2008) Wnt and beyond Wnt: multiple mechanisms control the transcriptional property of beta-catenin. Cell Signal 20:1697-1704
    • (2008) Cell Signal , vol.20 , pp. 1697-1704
    • Jin, T.1    George Fantus, I.2    Sun, J.3
  • 90
    • 0029772318 scopus 로고    scopus 로고
    • An essential e box in the promoter of the gene encoding the mRNA cap-binding protein (eukaryotic initiation factor 4E) is a target for activation by c-myc
    • Jones RM, Branda J, Johnston KA, Polymenis M, Gadd M, Rustgi A, Callanan L, Schmidt EV (1996) An essential E box in the promoter of the gene encoding the mRNA cap-binding protein (eukaryotic initiation factor 4E) is a target for activation by c-myc. Mol Cell Biol 16:4754-4764
    • (1996) Mol Cell Biol , vol.16 , pp. 4754-4764
    • Jones, R.M.1    Branda, J.2    Johnston, K.A.3    Polymenis, M.4    Gadd, M.5    Rustgi, A.6    Callanan, L.7    Schmidt, E.V.8
  • 91
    • 2942522541 scopus 로고    scopus 로고
    • Characterization of mammalian eIF4E-family members
    • Joshi B, Cameron A, Jagus R (2004) Characterization of mammalian eIF4E-family members. Eur J Biochem 271:2189-2203
    • (2004) Eur J Biochem , vol.271 , pp. 2189-2203
    • Joshi, B.1    Cameron, A.2    Jagus, R.3
  • 92
    • 84892486161 scopus 로고    scopus 로고
    • Mnk kinases in cytokine signaling and regulation of cytokine responses
    • Joshi S, Platanias LC (2012) Mnk kinases in cytokine signaling and regulation of cytokine responses. Biomol Concepts 3:127-139
    • (2012) Biomol Concepts , vol.3 , pp. 127-139
    • Joshi, S.1    Platanias, L.C.2
  • 93
    • 78249277326 scopus 로고    scopus 로고
    • Mechanisms of mRNA translation of interferon stimulated genes
    • Joshi S, Kaur S, Kroczynska B, Platanias LC (2010) Mechanisms of mRNA translation of interferon stimulated genes. Cytokine 52:123-127
    • (2010) Cytokine , vol.52 , pp. 123-127
    • Joshi, S.1    Kaur, S.2    Kroczynska, B.3    Platanias, L.C.4
  • 94
    • 20344387465 scopus 로고    scopus 로고
    • Active Src elevates the expression of betacatenin by enhancement of cap-dependent translation
    • Karni R, Gus Y, Dor Y, Meyuhas O, Levitzki A (2005) Active Src elevates the expression of betacatenin by enhancement of cap-dependent translation. Mol Cell Biol 25:5031-5039
    • (2005) Mol Cell Biol , vol.25 , pp. 5031-5039
    • Karni, R.1    Gus, Y.2    Dor, Y.3    Meyuhas, O.4    Levitzki, A.5
  • 95
    • 0028918259 scopus 로고
    • The proto-oncogene/translation factor eIF4E: A survey of its expression in breast carcinomas
    • Kerekatte V, Smiley K, Hu B, Smith A, Gelder F, De Benedetti A (1995) The proto-oncogene/translation factor eIF4E: a survey of its expression in breast carcinomas. Int J Cancer 64:27-31
    • (1995) Int J Cancer , vol.64 , pp. 27-31
    • Kerekatte, V.1    Smiley, K.2    Hu, B.3    Smith, A.4    Gelder, F.5    De Benedetti, A.6
  • 96
    • 0029967638 scopus 로고    scopus 로고
    • Translational regulation of vascular permeability factor by eukaryotic initiation factor 4E: Implications for tumor angiogenesis
    • Kevil CG, De Benedetti A, Payne DK, Coe LL, Laroux FS, Alexander JS (1996) Translational regulation of vascular permeability factor by eukaryotic initiation factor 4E: implications for tumor angiogenesis. Int J Cancer 65:785-790
    • (1996) Int J Cancer , vol.65 , pp. 785-790
    • Kevil, C.G.1    De Benedetti, A.2    Payne, D.K.3    Coe, L.L.4    Laroux, F.S.5    Alexander, J.S.6
  • 97
    • 84866544803 scopus 로고    scopus 로고
    • Up-regulation of translation eukaryotic initiation factor 4E in nucleophosmin 1 haploinsufficient cells results in changes in CCAAT enhancer-binding protein alpha activity: Implications in myelodysplastic syndrome and acute myeloid leukemia
    • Khanna-Gupta A, Abayasekara N, Levine M, Sun H, Virgilio M, Nia N, Halene S, Sportoletti P, Jeong JY, Pandolfi PP et al. (2012) Up-regulation of translation eukaryotic initiation factor 4E in nucleophosmin 1 haploinsufficient cells results in changes in CCAAT enhancer-binding protein alpha activity: implications in myelodysplastic syndrome and acute myeloid leukemia. J Biol Chem 287:32728-32737
    • (2012) J Biol Chem , vol.287 , pp. 32728-32737
    • Khanna-Gupta, A.1    Abayasekara, N.2    Levine, M.3    Sun, H.4    Virgilio, M.5    Nia, N.6    Halene, S.7    Sportoletti, P.8    Jeong, J.Y.9    Pandolfi, P.P.10
  • 99
    • 79952961510 scopus 로고    scopus 로고
    • Expression and phosphorylation of eukaryotic translation initiation factor 4E binding protein 1 in B-cell lymphomas and reactive lymphoid tissues
    • Kodali D, Rawal A, Ninan MJ, Patel MR, Mesa H, Knapp D, Schnitzer B, Kratzke RA, Gupta P (2011) Expression and phosphorylation of eukaryotic translation initiation factor 4E binding protein 1 in B-cell lymphomas and reactive lymphoid tissues. Arch Pathol Lab Med 135:365-371
    • (2011) Arch Pathol Lab Med , vol.135 , pp. 365-371
    • Kodali, D.1    Rawal, A.2    Ninan, M.J.3    Patel, M.R.4    Mesa, H.5    Knapp, D.6    Schnitzer, B.7    Kratzke, R.A.8    Gupta, P.9
  • 100
    • 84862881961 scopus 로고    scopus 로고
    • Attenuation of TORC1 signaling delays replicative and oncogenic RAS-induced senescence
    • Kolesnichenko M, Hong L, Liao R, Vogt PK, Sun P (2012) Attenuation of TORC1 signaling delays replicative and oncogenic RAS-induced senescence. Cell Cycle 11:2391-2401
    • (2012) Cell Cycle , vol.11 , pp. 2391-2401
    • Kolesnichenko, M.1    Hong, L.2    Liao, R.3    Vogt, P.K.4    Sun, P.5
  • 101
    • 79952223149 scopus 로고    scopus 로고
    • Therapeutic inhibition of MAP kinase interacting kinase blocks eukaryotic initiation factor 4E phosphorylation and suppresses outgrowth of experimental lung metastases
    • Konicek BW, Stephens JR, McNulty AM, Robichaud N, Peery RB, Dumstorf CA, Dowless MS, Iversen PW, Parsons S, Ellis KE et al. (2011) Therapeutic inhibition of MAP kinase interacting kinase blocks eukaryotic initiation factor 4E phosphorylation and suppresses outgrowth of experimental lung metastases. Cancer Res 71:1849-1857
    • (2011) Cancer Res , vol.71 , pp. 1849-1857
    • Konicek, B.W.1    Stephens, J.R.2    McNulty, A.M.3    Robichaud, N.4    Peery, R.B.5    Dumstorf, C.A.6    Dowless, M.S.7    Iversen, P.W.8    Parsons, S.9    Ellis, K.E.10
  • 102
    • 0026723117 scopus 로고
    • MRNAs containing extensive secondary structure in their 5? non-coding region translate efficiently in cells overexpressing initiation factor eIF-4E
    • Koromilas AE, Lazaris-Karatzas A, Sonenberg N (1992) mRNAs containing extensive secondary structure in their 5? non-coding region translate efficiently in cells overexpressing initiation factor eIF-4E. EMBO J 11:4153-4158
    • (1992) EMBO J , vol.11 , pp. 4153-4158
    • Koromilas, A.E.1    Lazaris-Karatzas, A.2    Sonenberg, N.3
  • 104
    • 34547114029 scopus 로고    scopus 로고
    • Eukaryotic translation initiation factor 4E induced progression of primary human mammary epithelial cells along the cancer pathway is associated with targeted translational deregulation of oncogenic drivers and inhibitors
    • Larsson O, Li S, Issaenko OA, Avdulov S, Peterson M, Smith K, Bitterman PB, Polunovsky VA (2007) Eukaryotic translation initiation factor 4E induced progression of primary human mammary epithelial cells along the cancer pathway is associated with targeted translational deregulation of oncogenic drivers and inhibitors. Cancer Res 67:6814-6824
    • (2007) Cancer Res , vol.67 , pp. 6814-6824
    • Larsson, O.1    Li, S.2    Issaenko, O.A.3    Avdulov, S.4    Peterson, M.5    Smith, K.6    Bitterman, P.B.7    Polunovsky, V.A.8
  • 107
    • 0025314596 scopus 로고
    • Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5? cap
    • Lazaris-Karatzas A, Montine KS, Sonenberg N (1990) Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5? cap. Nature 345:544-547
    • (1990) Nature , vol.345 , pp. 544-547
    • Lazaris-Karatzas, A.1    Montine, K.S.2    Sonenberg, N.3
  • 110
    • 0030940199 scopus 로고    scopus 로고
    • Overexpression of eukaryotic initiation factor 4E (eIF4E) in breast carcinoma
    • Li BD, Liu L, Dawson M, De Benedetti A (1997) Overexpression of eukaryotic initiation factor 4E (eIF4E) in breast carcinoma. Cancer 79:2385-2390
    • (1997) Cancer , vol.79 , pp. 2385-2390
    • Li, B.D.1    Liu, L.2    Dawson, M.3    De Benedetti, A.4
  • 111
    • 0031795848 scopus 로고    scopus 로고
    • Clinical outcome in stage i to III breast carcinoma and eIF4E overexpression
    • discussion 761-763
    • Li BD, McDonald JC, Nassar R, De Benedetti A (1998) Clinical outcome in stage I to III breast carcinoma and eIF4E overexpression. Ann Surg 227:756-761; discussion 761-763
    • (1998) Ann Surg , vol.227 , pp. 756-761
    • Li, B.D.1    McDonald, J.C.2    Nassar, R.3    De Benedetti, A.4
  • 112
    • 0036236341 scopus 로고    scopus 로고
    • Prospective study of eukaryotic initiation factor 4E protein elevation and breast cancer outcome
    • discussion 738-739
    • Li BD, Gruner JS, Abreo F, Johnson LW, Yu H, Nawas S, McDonald JC, DeBenedetti A (2002) Prospective study of eukaryotic initiation factor 4E protein elevation and breast cancer outcome. Ann Surg 235:732-738; discussion 738-739
    • (2002) Ann Surg , vol.235 , pp. 732-738
    • Li, B.D.1    Gruner, J.S.2    Abreo, F.3    Johnson, L.W.4    Yu, H.5    Nawas, S.6    McDonald, J.C.7    Debenedetti, A.8
  • 115
    • 84863229979 scopus 로고    scopus 로고
    • Elevated expression of eukaryotic translation initiation factor 4E is associated with proliferation, invasion and acquired resistance to erlotinib in lung cancer
    • Li Y, Fan S, Koo J, Yue P, Chen ZG, Owonikoko TK, Ramalingam SS, Khuri FR, Sun SY (2012) Elevated expression of eukaryotic translation initiation factor 4E is associated with proliferation, invasion and acquired resistance to erlotinib in lung cancer. Cancer Biol Ther 13:272-280
    • (2012) Cancer Biol Ther , vol.13 , pp. 272-280
    • Li, Y.1    Fan, S.2    Koo, J.3    Yue, P.4    Chen, Z.G.5    Owonikoko, T.K.6    Ramalingam, S.S.7    Khuri, F.R.8    Sun, S.Y.9
  • 116
    • 84873396333 scopus 로고    scopus 로고
    • Treatment of breast and lung cancer cells with a N-7 benzyl guanosine monophosphate tryptamine phosphoramidate pronucleotide (4Ei-1) results in chemosensitization to gemcitabine and induced eIF4E proteasomal degradation
    • Li S, Jia Y, Jacobson B, McCauley J, Kratzke R, Bitterman PB, Wagner CR (2013) Treatment of breast and lung cancer cells with a N-7 benzyl guanosine monophosphate tryptamine phosphoramidate pronucleotide (4Ei-1) results in chemosensitization to gemcitabine and induced eIF4E proteasomal degradation. Mol Pharm 10:523-531
    • (2013) Mol Pharm , vol.10 , pp. 523-531
    • Li, S.1    Jia, Y.2    Jacobson, B.3    McCauley, J.4    Kratzke, R.5    Bitterman, P.B.6    Wagner, C.R.7
  • 118
    • 0029912854 scopus 로고    scopus 로고
    • Control of the translational regulators PHAS-I and PHAS-II by insulin and cAMP in 3T3-L1 adipocytes
    • Lin TA, Lawrence JC Jr (1996) Control of the translational regulators PHAS-I and PHAS-II by insulin and cAMP in 3T3-L1 adipocytes. J Biol Chem 271:30199-30204
    • (1996) J Biol Chem , vol.271 , pp. 30199-30204
    • Lin, T.A.1    Lawrence, J.C.2
  • 119
    • 48549094467 scopus 로고    scopus 로고
    • C-Myc and eIF4F are components of a feedforward loop that links transcription and translation
    • Lin CJ, Cencic R, Mills JR, Robert F, Pelletier J (2008) c-Myc and eIF4F are components of a feedforward loop that links transcription and translation. Cancer Res 68:5326-5334
    • (2008) Cancer Res , vol.68 , pp. 5326-5334
    • Lin, C.J.1    Cencic, R.2    Mills, J.R.3    Robert, F.4    Pelletier, J.5
  • 121
    • 84889564693 scopus 로고    scopus 로고
    • Interaction of the eukaryotic initiation factor 4E with 4E-BP2 at a dynamic bipartite interface
    • Lukhele S, Bah A, Lin H, Sonenberg N, Forman-Kay JD (2013) Interaction of the eukaryotic initiation factor 4E with 4E-BP2 at a dynamic bipartite interface. Structure 21:2186-2196
    • (2013) Structure , vol.21 , pp. 2186-2196
    • Lukhele, S.1    Bah, A.2    Lin, H.3    Sonenberg, N.4    Forman-Kay, J.D.5
  • 122
    • 0942298123 scopus 로고    scopus 로고
    • Activated eIF4E-binding protein slows G1 progression and blocks transformation by c-myc without inhibiting cell growth
    • Lynch M, Fitzgerald C, Johnston KA, Wang S, Schmidt EV (2004) Activated eIF4E-binding protein slows G1 progression and blocks transformation by c-myc without inhibiting cell growth. J Biol Chem 279:3327-3339
    • (2004) J Biol Chem , vol.279 , pp. 3327-3339
    • Lynch, M.1    Fitzgerald, C.2    Johnston, K.A.3    Wang, S.4    Schmidt, E.V.5
  • 123
    • 22544464680 scopus 로고    scopus 로고
    • HnRNP K binds a core polypyrimidine element in the eukaryotic translation initiation factor 4E (eIF4E) promoter, and its regulation of eIF4E contributes to neoplastic transformation
    • Lynch M, Chen L, Ravitz MJ, Mehtani S, Korenblat K, Pazin MJ, Schmidt EV (2005) hnRNP K binds a core polypyrimidine element in the eukaryotic translation initiation factor 4E (eIF4E) promoter, and its regulation of eIF4E contributes to neoplastic transformation. Mol Cell Biol 25:6436-6453
    • (2005) Mol Cell Biol , vol.25 , pp. 6436-6453
    • Lynch, M.1    Chen, L.2    Ravitz, M.J.3    Mehtani, S.4    Korenblat, K.5    Pazin, M.J.6    Schmidt, E.V.7
  • 124
    • 0029166687 scopus 로고
    • The translation initiation factor eIF-4E binds to a common motif shared by the translation factor eIF-4 gamma and the translational repressors 4E-binding proteins
    • Mader S, Lee H, Pause A, Sonenberg N (1995) The translation initiation factor eIF-4E binds to a common motif shared by the translation factor eIF-4 gamma and the translational repressors 4E-binding proteins. Mol Cell Biol 15:4990-4997
    • (1995) Mol Cell Biol , vol.15 , pp. 4990-4997
    • Mader, S.1    Lee, H.2    Pause, A.3    Sonenberg, N.4
  • 127
    • 0030728936 scopus 로고    scopus 로고
    • Cocrystal structure of the messenger RNA 5? cap-binding protein (eIF4E) bound to 7-methyl-GDP
    • Marcotrigiano J, Gingras AC, Sonenberg N, Burley SK (1997) Cocrystal structure of the messenger RNA 5? cap-binding protein (eIF4E) bound to 7-methyl-GDP. Cell 89:951-961
    • (1997) Cell , vol.89 , pp. 951-961
    • Marcotrigiano, J.1    Gingras, A.C.2    Sonenberg, N.3    Burley, S.K.4
  • 128
    • 0033152072 scopus 로고    scopus 로고
    • Cap-dependent translation initiation in eukaryotes is regulated by a molecular mimic of eIF4G
    • Marcotrigiano J, Gingras AC, Sonenberg N, Burley SK (1999) Cap-dependent translation initiation in eukaryotes is regulated by a molecular mimic of eIF4G. Mol cell 3:707-716
    • (1999) Mol Cell , vol.3 , pp. 707-716
    • Marcotrigiano, J.1    Gingras, A.C.2    Sonenberg, N.3    Burley, S.K.4
  • 130
    • 84899982907 scopus 로고    scopus 로고
    • Accumulation of dephosphorylated 4EBP after mTOR inhibition with rapamycin is sufficient to disrupt paracrine transformation by the KSHV vGPCR oncogene
    • Martin D, Nguyen Q, Molinolo A, Gutkind JS (2014) Accumulation of dephosphorylated 4EBP after mTOR inhibition with rapamycin is sufficient to disrupt paracrine transformation by the KSHV vGPCR oncogene. Oncogene 33:2405-2412
    • (2014) Oncogene , vol.33 , pp. 2405-2412
    • Martin, D.1    Nguyen, Q.2    Molinolo, A.3    Gutkind, J.S.4
  • 131
    • 84873739231 scopus 로고    scopus 로고
    • Anti-oncogenic potential of the eIF4E-binding proteins
    • Martineau Y, Azar R, Bousquet C, Pyronnet S (2013) Anti-oncogenic potential of the eIF4E-binding proteins. Oncogene 32:671-677
    • (2013) Oncogene , vol.32 , pp. 671-677
    • Martineau, Y.1    Azar, R.2    Bousquet, C.3    Pyronnet, S.4
  • 139
    • 0030013326 scopus 로고    scopus 로고
    • Stimulation of protein synthesis, eukaryotic translation initiation factor 4E phosphorylation, and PHAS-I phosphorylation by insulin requires insulin receptor substrate 1 and phosphatidylinositol 3-kinase
    • Mendez R, Myers MG Jr, White MF, Rhoads RE (1996) Stimulation of protein synthesis, eukaryotic translation initiation factor 4E phosphorylation, and PHAS-I phosphorylation by insulin requires insulin receptor substrate 1 and phosphatidylinositol 3-kinase. Mol Cell Biol 16:2857-2864
    • (1996) Mol Cell Biol , vol.16 , pp. 2857-2864
    • Mendez, R.1    Myers, M.G.2    White, M.F.3    Rhoads, R.E.4
  • 141
    • 53049087996 scopus 로고    scopus 로고
    • Importance of C-terminal flexible region of 4E-binding protein in binding with eukaryotic initiation factor 4E
    • Mizuno A, In Y, Fujita Y, Abiko F, Miyagawa H, Kitamura K, Tomoo K, Ishida T (2008) Importance of C-terminal flexible region of 4E-binding protein in binding with eukaryotic initiation factor 4E. FEBS Lett 582:3439-3444
    • (2008) FEBS Lett , vol.582 , pp. 3439-3444
    • Mizuno, A.1    In, Y.2    Fujita, Y.3    Abiko, F.4    Miyagawa, H.5    Kitamura, K.6    Tomoo, K.7    Ishida, T.8
  • 144
    • 33646415906 scopus 로고    scopus 로고
    • Survival signaling by Notch1: Mammalian target of rapamycin (mTOR)-dependent inhibition of p53
    • Mungamuri SK, Yang X, Thor AD, Somasundaram K (2006) Survival signaling by Notch1: mammalian target of rapamycin (mTOR)-dependent inhibition of p53. Cancer Res 66:4715-4724
    • (2006) Cancer Res , vol.66 , pp. 4715-4724
    • Mungamuri, S.K.1    Yang, X.2    Thor, A.D.3    Somasundaram, K.4
  • 145
    • 33746374438 scopus 로고    scopus 로고
    • Ubiquitination and proteasome-dependent degradation of human eukaryotic translation initiation factor 4E
    • Murata T, Shimotohno K (2006) Ubiquitination and proteasome-dependent degradation of human eukaryotic translation initiation factor 4E. J Biol Chem 281:20788-20800
    • (2006) J Biol Chem , vol.281 , pp. 20788-20800
    • Murata, T.1    Shimotohno, K.2
  • 146
    • 84874106479 scopus 로고    scopus 로고
    • EIF4F suppression in breast cancer affects maintenance and progression
    • Nasr Z, Robert F, Porco JA, Jr., Muller WJ, Pelletier J (2013) eIF4F suppression in breast cancer affects maintenance and progression. Oncogene 33:861-871
    • (2013) Oncogene , vol.33 , pp. 861-871
    • Nasr, Z.1    Robert, F.2    Porco, J.A.3    Muller, W.J.4    Pelletier, J.5
  • 148
    • 0030808698 scopus 로고    scopus 로고
    • Detection of the protooncogene eIF4E in surgical margins may predict recurrence in head and neck cancer
    • Nathan CO, Liu L, Li BD, Abreo FW, Nandy I, De Benedetti A (1997b) Detection of the protooncogene eIF4E in surgical margins may predict recurrence in head and neck cancer. Oncogene 15:579-584
    • (1997) Oncogene , vol.15 , pp. 579-584
    • Nathan, C.O.1    Liu, L.2    Li, B.D.3    Abreo, F.W.4    Nandy, I.5    De Benedetti, A.6
  • 149
    • 0032857344 scopus 로고    scopus 로고
    • Analysis of surgical margins with the molecular marker eIF4E: A prognostic factor in patients with head and neck cancer
    • Nathan CO, Franklin S, Abreo FW, Nassar R, De Benedetti A, Glass J (1999a) Analysis of surgical margins with the molecular marker eIF4E: a prognostic factor in patients with head and neck cancer. J Clin Oncol 17:2909-2914
    • (1999) J Clin Oncol , vol.17 , pp. 2909-2914
    • Nathan, C.O.1    Franklin, S.2    Abreo, F.W.3    Nassar, R.4    De Benedetti, A.5    Glass, J.6
  • 151
    • 4444278397 scopus 로고    scopus 로고
    • Overexpressed eIF4E is functionally active in surgical margins of head and neck cancer patients via activation of the Akt/mammalian target of rapamycin pathway
    • Nathan CO, Amirghahari N, Abreo F, Rong X, Caldito G, Jones ML, Zhou H, Smith M, Kimberly D, Glass J (2004) Overexpressed eIF4E is functionally active in surgical margins of head and neck cancer patients via activation of the Akt/mammalian target of rapamycin pathway. Clin Cancer Res 10:5820-5827
    • (2004) Clin Cancer Res , vol.10 , pp. 5820-5827
    • Nathan, C.O.1    Amirghahari, N.2    Abreo, F.3    Rong, X.4    Caldito, G.5    Jones, M.L.6    Zhou, H.7    Smith, M.8    Kimberly, D.9    Glass, J.10
  • 156
    • 33745813943 scopus 로고    scopus 로고
    • Deregulation of eIF4E: 4E-BP1 in differentiated human papillomavirus-containing cells leads to high levels of expression of the E7 oncoprotein
    • Oh KJ, Kalinina A, Park NH, Bagchi S (2006) Deregulation of eIF4E: 4E-BP1 in differentiated human papillomavirus-containing cells leads to high levels of expression of the E7 oncoprotein. J Virol 80:7079-7088
    • (2006) J Virol , vol.80 , pp. 7079-7088
    • Oh, K.J.1    Kalinina, A.2    Park, N.H.3    Bagchi, S.4
  • 159
    • 0028034233 scopus 로고
    • Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5?-cap function
    • Pause A, Belsham GJ, Gingras AC, Donze O, Lin TA, Lawrence JC Jr, Sonenberg N (1994a) Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5?-cap function. Nature 371:762-767
    • (1994) Nature , vol.371 , pp. 762-767
    • Pause, A.1    Belsham, G.J.2    Gingras, A.C.3    Donze, O.4    Lin, T.A.5    Lawrence, J.C.6    Sonenberg, N.7
  • 160
    • 0028197298 scopus 로고
    • Dominant negative mutants of mammalian translation initiation factor eIF-4A define a critical role for eIF-4F in cap-dependent and cap-independent initiation of translation
    • Pause A, Methot N, Svitkin Y, Merrick WC, Sonenberg N (1994b) Dominant negative mutants of mammalian translation initiation factor eIF-4A define a critical role for eIF-4F in cap-dependent and cap-independent initiation of translation. EMBO J 13:1205-1215
    • (1994) EMBO J , vol.13 , pp. 1205-1215
    • Pause, A.1    Methot, N.2    Svitkin, Y.3    Merrick, W.C.4    Sonenberg, N.5
  • 161
    • 0037112055 scopus 로고    scopus 로고
    • The roles of individual eukaryotic translation initiation factors in ribosomal scanning and initiation codon selection
    • Pestova TV, Kolupaeva VG (2002) The roles of individual eukaryotic translation initiation factors in ribosomal scanning and initiation codon selection. Genes Dev 16:2906-2922
    • (2002) Genes Dev , vol.16 , pp. 2906-2922
    • Pestova, T.V.1    Kolupaeva, V.G.2
  • 162
    • 34248216623 scopus 로고    scopus 로고
    • Phosphoprotein pathway mapping: Akt/mammalian target of rapamycin activation is negatively associated with childhood rhabdomyosarcoma survival
    • Petricoin EF III, Espina V, Araujo RP, Midura B, Yeung C, Wan X, Eichler GS, Johann DJ Jr, Qualman S, Tsokos M et al. (2007) Phosphoprotein pathway mapping: Akt/mammalian target of rapamycin activation is negatively associated with childhood rhabdomyosarcoma survival. Cancer Res 67:3431-3440
    • (2007) Cancer Res , vol.67 , pp. 3431-3440
    • Petricoin, E.F.1    Espina, V.2    Araujo, R.P.3    Midura, B.4    Yeung, C.5    Wan, X.6    Eichler, G.S.7    Johann, D.J.8    Qualman, S.9    Tsokos, M.10
  • 166
    • 40449114196 scopus 로고    scopus 로고
    • MNK1 and EIF4E are downstream effectors of MEKs in the regulation of the nuclear export of HDM2 mRNA
    • Phillips A, Blaydes JP (2008) MNK1 and EIF4E are downstream effectors of MEKs in the regulation of the nuclear export of HDM2 mRNA. Oncogene 27:1645-1649
    • (2008) Oncogene , vol.27 , pp. 1645-1649
    • Phillips, A.1    Blaydes, J.P.2
  • 167
    • 84880859236 scopus 로고    scopus 로고
    • Vitronectin-alphavbeta3 Integrin Engagement Directs Hypoxia-Resistant mTOR Activity and Sustained Protein Synthesis Linked to Invasion by Breast Cancer Cells
    • Pola C, Formenti SC, Schneider RJ (2013) Vitronectin-alphavbeta3 Integrin Engagement Directs Hypoxia-Resistant mTOR Activity and Sustained Protein Synthesis Linked to Invasion by Breast Cancer Cells. Cancer Res 73:4571-4578
    • (2013) Cancer Res , vol.73 , pp. 4571-4578
    • Pola, C.1    Formenti, S.C.2    Schneider, R.J.3
  • 168
    • 84880352272 scopus 로고    scopus 로고
    • Myc and mTOR converge on a common node in protein synthesis control that confers synthetic lethality in Myc-driven cancers
    • Pourdehnad M, Truitt ML, Siddiqi IN, Ducker GS, Shokat KM, Ruggero D (2013) Myc and mTOR converge on a common node in protein synthesis control that confers synthetic lethality in Myc-driven cancers. Proc Natl Acad Sci U S A 110:11988-11993
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 11988-11993
    • Pourdehnad, M.1    Truitt, M.L.2    Siddiqi, I.N.3    Ducker, G.S.4    Shokat, K.M.5    Ruggero, D.6
  • 170
    • 0037781584 scopus 로고    scopus 로고
    • Conducting the initiation of protein synthesis: The role of eIF4G
    • Prevot D, Darlix JL, Ohlmann T (2003) Conducting the initiation of protein synthesis: the role of eIF4G. Biol Cell 95:141-156
    • (2003) Biol Cell , vol.95 , pp. 141-156
    • Prevot, D.1    Darlix, J.L.2    Ohlmann, T.3
  • 171
    • 77951589688 scopus 로고    scopus 로고
    • Cooperation between translating ribosomes and RNA polymerase in transcription elongation
    • Proshkin S, Rahmouni AR, Mironov A, Nudler E (2010) Cooperation between translating ribosomes and RNA polymerase in transcription elongation. Science 328:504-508
    • (2010) Science , vol.328 , pp. 504-508
    • Proshkin, S.1    Rahmouni, A.R.2    Mironov, A.3    Nudler, E.4
  • 172
    • 33745627305 scopus 로고    scopus 로고
    • Global alterations in mRNA polysomal recruitment in a cell model of colorectal cancer progression to metastasis
    • Provenzani A, Fronza R, Loreni F, Pascale A, Amadio M, Quattrone A (2006) Global alterations in mRNA polysomal recruitment in a cell model of colorectal cancer progression to metastasis. Carcinogenesis 27:1323-1333
    • (2006) Carcinogenesis , vol.27 , pp. 1323-1333
    • Provenzani, A.1    Fronza, R.2    Loreni, F.3    Pascale, A.4    Amadio, M.5    Quattrone, A.6
  • 173
    • 0032541425 scopus 로고    scopus 로고
    • Cooperative modulation by eIF4G of eIF4E-binding to the mRNA 5? cap in yeast involves a site partially shared by p20
    • Ptushkina M, von der Haar T, Vasilescu S, Frank R, Birkenhager R, McCarthy JE (1998) Cooperative modulation by eIF4G of eIF4E-binding to the mRNA 5? cap in yeast involves a site partially shared by p20. EMBO J 17: 4798-4808
    • (1998) EMBO J , vol.17 , pp. 4798-4808
    • Ptushkina, M.1    Von Der Haar, T.2    Vasilescu, S.3    Frank, R.4    Birkenhager, R.5    McCarthy, J.E.6
  • 174
    • 0033521535 scopus 로고    scopus 로고
    • Human eukaryotic translation initiation factor 4G (eIF4G) recruits mnk1 to phosphorylate eIF4E
    • Pyronnet S, Imataka H, Gingras AC, Fukunaga R, Hunter T, Sonenberg N (1999) Human eukaryotic translation initiation factor 4G (eIF4G) recruits mnk1 to phosphorylate eIF4E. EMBO J 18:270-279
    • (1999) EMBO J , vol.18 , pp. 270-279
    • Pyronnet, S.1    Imataka, H.2    Gingras, A.C.3    Fukunaga, R.4    Hunter, T.5    Sonenberg, N.6
  • 175
    • 0242361561 scopus 로고    scopus 로고
    • Oncogenic Ras and Akt signaling contribute to glioblastoma formation by differential recruitment of existing mRNAs to polysomes
    • Rajasekhar VK, Viale A, Socci ND, Wiedmann M, Hu X, Holland EC (2003) Oncogenic Ras and Akt signaling contribute to glioblastoma formation by differential recruitment of existing mRNAs to polysomes. Mol Cell 12:889-901
    • (2003) Mol Cell , vol.12 , pp. 889-901
    • Rajasekhar, V.K.1    Viale, A.2    Socci, N.D.3    Wiedmann, M.4    Hu, X.5    Holland, E.C.6
  • 176
    • 73449138471 scopus 로고    scopus 로고
    • Translation initiation: A critical signalling node in cancer
    • Robert F, Pelletier J (2009) Translation initiation: a critical signalling node in cancer. Expert Opin Ther Targets 13:1279-1293
    • (2009) Expert Opin Ther Targets , vol.13 , pp. 1279-1293
    • Robert, F.1    Pelletier, J.2
  • 180
    • 0027365517 scopus 로고
    • Elevated levels of cyclin D1 protein in response to increased expression of eukaryotic initiation factor 4E
    • Rosenwald IB, Lazaris-Karatzas A, Sonenberg N, Schmidt EV (1993) Elevated levels of cyclin D1 protein in response to increased expression of eukaryotic initiation factor 4E. Mol Cell Biol 13:7358-7363
    • (1993) Mol Cell Biol , vol.13 , pp. 7358-7363
    • Rosenwald, I.B.1    Lazaris-Karatzas, A.2    Sonenberg, N.3    Schmidt, E.V.4
  • 182
    • 0039656540 scopus 로고    scopus 로고
    • Upregulation of protein synthesis initiation factor eIF-4E is an early event during colon carcinogenesis
    • Rosenwald IB, Chen JJ, Wang S, Savas L, London IM, Pullman J (1999) Upregulation of protein synthesis initiation factor eIF-4E is an early event during colon carcinogenesis. Oncogene 18:2507-2517
    • (1999) Oncogene , vol.18 , pp. 2507-2517
    • Rosenwald, I.B.1    Chen, J.J.2    Wang, S.3    Savas, L.4    London, I.M.5    Pullman, J.6
  • 183
    • 0035886531 scopus 로고    scopus 로고
    • Expression of eukaryotic translation initiation factors 4E and 2alpha is increased frequently in bronchioloalveolar but not in squamous cell carcinomas of the lung
    • Rosenwald IB, Hutzler MJ, Wang S, Savas L, Fraire AE (2001) Expression of eukaryotic translation initiation factors 4E and 2alpha is increased frequently in bronchioloalveolar but not in squamous cell carcinomas of the lung. Cancer 92:2164-2171
    • (2001) Cancer , vol.92 , pp. 2164-2171
    • Rosenwald, I.B.1    Hutzler, M.J.2    Wang, S.3    Savas, L.4    Fraire, A.E.5
  • 184
    • 0030443685 scopus 로고    scopus 로고
    • The eIF4E-binding proteins 1 and 2 are negative regulators of cell growth
    • Rousseau D, Gingras AC, Pause A, Sonenberg N (1996a) The eIF4E-binding proteins 1 and 2 are negative regulators of cell growth. Oncogene 13:2415-2420
    • (1996) Oncogene , vol.13 , pp. 2415-2420
    • Rousseau, D.1    Gingras, A.C.2    Pause, A.3    Sonenberg, N.4
  • 185
    • 0030041884 scopus 로고    scopus 로고
    • Translation initiation of ornithine decarboxylase and nucleocytoplasmic transport of cyclin D1 mRNA are increased in cells overexpressing eukaryotic initiation factor 4E
    • Rousseau D, Kaspar R, Rosenwald I, Gehrke L, Sonenberg N (1996b) Translation initiation of ornithine decarboxylase and nucleocytoplasmic transport of cyclin D1 mRNA are increased in cells overexpressing eukaryotic initiation factor 4E. Proc Natl Acad Sci U S A 93:1065-1070
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 1065-1070
    • Rousseau, D.1    Kaspar, R.2    Rosenwald, I.3    Gehrke, L.4    Sonenberg, N.5
  • 186
    • 2442648845 scopus 로고    scopus 로고
    • The translation factor eIF-4E promotes tumor formation and cooperates with c-Myc in lymphomagenesis
    • Ruggero D, Montanaro L, Ma L, Xu W, Londei P, Cordon-Cardo C, Pandolfi PP (2004) The translation factor eIF-4E promotes tumor formation and cooperates with c-Myc in lymphomagenesis. Nature Med 10:484-486
    • (2004) Nature Med , vol.10 , pp. 484-486
    • Ruggero, D.1    Montanaro, L.2    Ma, L.3    Xu, W.4    Londei, P.5    Cordon-Cardo, C.6    Pandolfi, P.P.7
  • 188
    • 33646089881 scopus 로고    scopus 로고
    • Expression of the eukaryotic translation initiation factor 4E (eIF4E) and 4E-BP1 in esophageal cancer
    • Salehi Z, Mashayekhi F (2006) Expression of the eukaryotic translation initiation factor 4E (eIF4E) and 4E-BP1 in esophageal cancer. Clin Biochem 39:404-409
    • (2006) Clin Biochem , vol.39 , pp. 404-409
    • Salehi, Z.1    Mashayekhi, F.2
  • 189
    • 34548483480 scopus 로고    scopus 로고
    • Significance of eIF4E expression in skin squamous cell carcinoma
    • Salehi Z, Mashayekhi F, Shahosseini F (2007) Significance of eIF4E expression in skin squamous cell carcinoma. Cell Biol Int 31:1400-1404
    • (2007) Cell Biol Int , vol.31 , pp. 1400-1404
    • Salehi, Z.1    Mashayekhi, F.2    Shahosseini, F.3
  • 191
    • 0036438924 scopus 로고    scopus 로고
    • Does phosphorylation of the cap-binding protein eIF4E play a role in translation initiation?
    • Scheper GC, Proud CG (2002) Does phosphorylation of the cap-binding protein eIF4E play a role in translation initiation? Eur J Biochem 269:5350-5359
    • (2002) Eur J Biochem , vol.269 , pp. 5350-5359
    • Scheper, G.C.1    Proud, C.G.2
  • 192
    • 0036479313 scopus 로고    scopus 로고
    • Phosphorylation of eukaryotic initiation factor 4E markedly reduces its affinity for capped mRNA
    • Scheper GC, van Kollenburg B, Hu J, Luo Y, Goss DJ, Proud CG (2002) Phosphorylation of eukaryotic initiation factor 4E markedly reduces its affinity for capped mRNA. J Biol Chem 277:3303-3309
    • (2002) J Biol Chem , vol.277 , pp. 3303-3309
    • Scheper, G.C.1    Van Kollenburg, B.2    Hu, J.3    Luo, Y.4    Goss, D.J.5    Proud, C.G.6
  • 194
    • 0031800113 scopus 로고    scopus 로고
    • Differential expression of vascular endothelial growth factor mRNA vs protein isoform expression in human breast cancer and relationship to eIF-4E
    • Scott PA, Smith K, Poulsom R, De Benedetti A, Bicknell R, Harris AL (1998) Differential expression of vascular endothelial growth factor mRNA vs protein isoform expression in human breast cancer and relationship to eIF-4E. Br J Cancer 77:2120-2128
    • (1998) Br J Cancer , vol.77 , pp. 2120-2128
    • Scott, P.A.1    Smith, K.2    Poulsom, R.3    De Benedetti, A.4    Bicknell, R.5    Harris, A.L.6
  • 195
    • 0034306997 scopus 로고    scopus 로고
    • Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability
    • Sears R, Nuckolls F, Haura E, Taya Y, Tamai K, Nevins JR (2000) Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability. Genes Dev 14:2501-2514
    • (2000) Genes Dev , vol.14 , pp. 2501-2514
    • Sears, R.1    Nuckolls, F.2    Haura, E.3    Taya, Y.4    Tamai, K.5    Nevins, J.R.6
  • 197
    • 78049401290 scopus 로고    scopus 로고
    • Prognostic significance of expression of eukaryotic initiation factor 4E and 4E binding protein 1 in patients with pathological stage i invasive lung adenocarcinoma
    • Seki N, Takasu T, Sawada S, Nakata M, Nishimura R, Segawa Y, Shibakuki R, Hanafusa T, Eguchi K (2010) Prognostic significance of expression of eukaryotic initiation factor 4E and 4E binding protein 1 in patients with pathological stage I invasive lung adenocarcinoma. Lung Cancer 70:329-334
    • (2010) Lung Cancer , vol.70 , pp. 329-334
    • Seki, N.1    Takasu, T.2    Sawada, S.3    Nakata, M.4    Nishimura, R.5    Segawa, Y.6    Shibakuki, R.7    Hanafusa, T.8    Eguchi, K.9
  • 200
    • 80052371597 scopus 로고    scopus 로고
    • Human Merkel cell polyomavirus small T antigen is an oncoprotein targeting the 4E-BP1 translation regulator
    • Shuda M, Kwun HJ, Feng H, Chang Y, Moore PS (2011) Human Merkel cell polyomavirus small T antigen is an oncoprotein targeting the 4E-BP1 translation regulator. J Clin Invest 121:3623-3634
    • (2011) J Clin Invest , vol.121 , pp. 3623-3634
    • Shuda, M.1    Kwun, H.J.2    Feng, H.3    Chang, Y.4    Moore, P.S.5
  • 201
    • 33744961739 scopus 로고    scopus 로고
    • Stopped-flow kinetic analysis of eIF4E and phosphorylated eIF4E binding to cap analogs and capped oligoribonucleotides: Evidence for a one-step binding mechanism
    • Slepenkov SV, Darzynkiewicz E, Rhoads RE (2006) Stopped-flow kinetic analysis of eIF4E and phosphorylated eIF4E binding to cap analogs and capped oligoribonucleotides: evidence for a one-step binding mechanism. J Biol Chem 281:14927-14938
    • (2006) J Biol Chem , vol.281 , pp. 14927-14938
    • Slepenkov, S.V.1    Darzynkiewicz, E.2    Rhoads, R.E.3
  • 202
    • 54449094585 scopus 로고    scopus 로고
    • Kinetic mechanism for assembly of the m7GpppG.eIF4E.eIF4G complex
    • Slepenkov SV, Korneeva NL, Rhoads RE (2008) Kinetic mechanism for assembly of the m7GpppG.eIF4E.eIF4G complex. J Biol Chem 283:25227-25237
    • (2008) J Biol Chem , vol.283 , pp. 25227-25237
    • Slepenkov, S.V.1    Korneeva, N.L.2    Rhoads, R.E.3
  • 203
    • 42149195978 scopus 로고    scopus 로고
    • EIF4E, the mRNA cap-binding protein: From basic discovery to translational research
    • Sonenberg N (2008) eIF4E, the mRNA cap-binding protein: from basic discovery to translational research. Biochem Cell Biol 86:178-183
    • (2008) Biochem Cell Biol , vol.86 , pp. 178-183
    • Sonenberg, N.1
  • 204
    • 60149091189 scopus 로고    scopus 로고
    • Regulation of translation initiation in eukaryotes: Mechanisms and biological targets
    • Sonenberg N, Hinnebusch AG (2009) Regulation of translation initiation in eukaryotes: mechanisms and biological targets. Cell 136:731-745
    • (2009) Cell , vol.136 , pp. 731-745
    • Sonenberg, N.1    Hinnebusch, A.G.2
  • 205
    • 0018143765 scopus 로고
    • A polypeptide in eukaryotic initiation factors that crosslinks specifically to the 5?-terminal cap in mRNA
    • Sonenberg N, Morgan MA, Merrick WC, Shatkin AJ (1978) A polypeptide in eukaryotic initiation factors that crosslinks specifically to the 5?-terminal cap in mRNA. Proc Natl Acad Sci U S A 75:4843-4847
    • (1978) Proc Natl Acad Sci U S A , vol.75 , pp. 4843-4847
    • Sonenberg, N.1    Morgan, M.A.2    Merrick, W.C.3    Shatkin, A.J.4
  • 206
    • 0019808864 scopus 로고
    • Probing the function of the eucaryotic 5? cap structure by using a monoclonal antibody directed against cap-binding proteins
    • Sonenberg N, Guertin D, Cleveland D, Trachsel H (1981) Probing the function of the eucaryotic 5? cap structure by using a monoclonal antibody directed against cap-binding proteins. Cell 27:563-572
    • (1981) Cell , vol.27 , pp. 563-572
    • Sonenberg, N.1    Guertin, D.2    Cleveland, D.3    Trachsel, H.4
  • 207
    • 84155197399 scopus 로고    scopus 로고
    • Regulation of cell growth by Notch signaling and its differential requirement in normal vs tumor-forming stem cells in Drosophila
    • Song Y, Lu B (2011) Regulation of cell growth by Notch signaling and its differential requirement in normal vs. tumor-forming stem cells in Drosophila. Genes Dev 25:2644-2658
    • (2011) Genes Dev , vol.25 , pp. 2644-2658
    • Song, Y.1    Lu, B.2
  • 211
    • 33846504772 scopus 로고    scopus 로고
    • Oncolytic virotherapy synergism with signaling inhibitors: Rapamycin increases myxoma virus tropism for human tumor cells
    • Stanford MM, Barrett JW, Nazarian SH, Werden S, McFadden G (2007) Oncolytic virotherapy synergism with signaling inhibitors: Rapamycin increases myxoma virus tropism for human tumor cells. J Virol 81:1251-1260
    • (2007) J Virol , vol.81 , pp. 1251-1260
    • Stanford, M.M.1    Barrett, J.W.2    Nazarian, S.H.3    Werden, S.4    McFadden, G.5
  • 212
    • 2542445449 scopus 로고    scopus 로고
    • Translation of the radioresistance kinase TLK1B is induced by gamma-irradiation through activation of mTOR and phosphorylation of 4E-BP1
    • Sunavala-Dossabhoy G, Fowler M, De Benedetti A (2004) Translation of the radioresistance kinase TLK1B is induced by gamma-irradiation through activation of mTOR and phosphorylation of 4E-BP1. BMC Mol Biol 5:1
    • (2004) BMC Mol Biol , vol.5 , pp. 1
    • Sunavala-Dossabhoy, G.1    Fowler, M.2    De Benedetti, A.3
  • 214
    • 0035032444 scopus 로고    scopus 로고
    • The requirement for eukaryotic initiation factor 4A (elF4A) in translation is in direct proportion to the degree of mRNA 5? secondary structure
    • Svitkin YV, Pause A, Haghighat A, Pyronnet S, Witherell G, Belsham GJ, Sonenberg N (2001) The requirement for eukaryotic initiation factor 4A (elF4A) in translation is in direct proportion to the degree of mRNA 5? secondary structure. RNA 7:382-394
    • (2001) RNA , vol.7 , pp. 382-394
    • Svitkin, Y.V.1    Pause, A.2    Haghighat, A.3    Pyronnet, S.4    Witherell, G.5    Belsham, G.J.6    Sonenberg, N.7
  • 218
    • 27844576586 scopus 로고    scopus 로고
    • Structural basis for mRNA Cap-Binding regulation of eukaryotic initiation factor 4E by 4E-binding protein, studied by spectroscopic, X-ray crystal structural, and molecular dynamics simulation methods
    • Tomoo K, Matsushita Y, Fujisaki H, Abiko F, Shen X, Taniguchi T, Miyagawa H, Kitamura K, Miura K, Ishida T (2005) Structural basis for mRNA Cap-Binding regulation of eukaryotic initiation factor 4E by 4E-binding protein, studied by spectroscopic, X-ray crystal structural, and molecular dynamics simulation methods. Biochim Biophys Acta 1753:191-208
    • (2005) Biochim Biophys Acta , vol.1753 , pp. 191-208
    • Tomoo, K.1    Matsushita, Y.2    Fujisaki, H.3    Abiko, F.4    Shen, X.5    Taniguchi, T.6    Miyagawa, H.7    Kitamura, K.8    Miura, K.9    Ishida, T.10
  • 219
    • 84867434398 scopus 로고    scopus 로고
    • MRNA Translation and Energy Metabolism in Cancer: The Role of the MAPK and mTORC1 Pathways
    • Topisirovic I, Sonenberg N (2011) mRNA Translation and Energy Metabolism in Cancer: The Role of the MAPK and mTORC1 Pathways. Cold Spring Harb Symp Quant Biol 76:355-367
    • (2011) Cold Spring Harb Symp Quant Biol , vol.76 , pp. 355-367
    • Topisirovic, I.1    Sonenberg, N.2
  • 220
    • 9244228003 scopus 로고    scopus 로고
    • Phosphorylation of the eukaryotic translation initiation factor eIF4E contributes to its transformation and mRNA transport activities
    • Topisirovic I, Ruiz-Gutierrez M, Borden KL (2004) Phosphorylation of the eukaryotic translation initiation factor eIF4E contributes to its transformation and mRNA transport activities. Cancer Res 64:8639-8642
    • (2004) Cancer Res , vol.64 , pp. 8639-8642
    • Topisirovic, I.1    Ruiz-Gutierrez, M.2    Borden, K.L.3
  • 221
    • 61749103876 scopus 로고    scopus 로고
    • Stability of eukaryotic translation initiation factor 4E mRNA is regulated by HuR, and this activity is dysregulated in cancer
    • Topisirovic I, Siddiqui N, Orolicki S, Skrabanek LA, Tremblay M, Hoang T, Borden KL (2009) Stability of eukaryotic translation initiation factor 4E mRNA is regulated by HuR, and this activity is dysregulated in cancer. Mol Cell Biol 29:1152-1162
    • (2009) Mol Cell Biol , vol.29 , pp. 1152-1162
    • Topisirovic, I.1    Siddiqui, N.2    Orolicki, S.3    Skrabanek, L.A.4    Tremblay, M.5    Hoang, T.6    Borden, K.L.7
  • 223
    • 84879636044 scopus 로고    scopus 로고
    • A detailed immunohistochemical analysis of the PI3K/AKT/mTOR pathway in lung cancer: Correlation with PIK3CA, AKT1, K-RAS or PTEN mutational status and clinicopathological features
    • Trigka EA, Levidou G, Saetta AA, Chatziandreou I, Tomos P, Thalassinos N, Anastasiou N, Spartalis E, Kavantzas N, Patsouris E et al. (2013) A detailed immunohistochemical analysis of the PI3K/AKT/mTOR pathway in lung cancer: correlation with PIK3CA, AKT1, K-RAS or PTEN mutational status and clinicopathological features. Oncol Rep 30:623-636
    • (2013) Oncol Rep , vol.30 , pp. 623-636
    • Trigka, E.A.1    Levidou, G.2    Saetta, A.A.3    Chatziandreou, I.4    Tomos, P.5    Thalassinos, N.6    Anastasiou, N.7    Spartalis, E.8    Kavantzas, N.9    Patsouris, E.10
  • 224
    • 0030589726 scopus 로고    scopus 로고
    • Tissue distribution, genomic structure, and chromosome mapping of mouse and human eukaryotic initiation factor 4E-binding proteins 1 and 2
    • Tsukiyama-Kohara K, Vidal SM, Gingras AC, Glover TW, Hanash SM, Heng H, Sonenberg N (1996) Tissue distribution, genomic structure, and chromosome mapping of mouse and human eukaryotic initiation factor 4E-binding proteins 1 and 2. Genomics 38:353-363
    • (1996) Genomics , vol.38 , pp. 353-363
    • Tsukiyama-Kohara, K.1    Vidal, S.M.2    Gingras, A.C.3    Glover, T.W.4    Hanash, S.M.5    Heng, H.6    Sonenberg, N.7
  • 225
    • 77956271160 scopus 로고    scopus 로고
    • Combined deficiency for MAP kinase-interacting kinase 1 and 2 (Mnk1 and Mnk2) delays tumor development
    • Ueda T, Sasaki M, Elia AJ, Chio II, Hamada K, Fukunaga R, Mak TW (2010) Combined deficiency for MAP kinase-interacting kinase 1 and 2 (Mnk1 and Mnk2) delays tumor development. Proc Natl Acad Sci U S A 107:13984-13990
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 13984-13990
    • Ueda, T.1    Sasaki, M.2    Elia, A.J.3    Chio, I.I.4    Hamada, K.5    Fukunaga, R.6    Mak, T.W.7
  • 226
    • 80054911203 scopus 로고    scopus 로고
    • Identification and function of the second eIF4E-binding region in N-terminal domain of eIF4G: Comparison with eIF4E-binding protein
    • Umenaga Y, Paku KS, In Y, Ishida T, Tomoo K (2011) Identification and function of the second eIF4E-binding region in N-terminal domain of eIF4G: comparison with eIF4E-binding protein. Biochem Biophys Res Commun 414:462-467
    • (2011) Biochem Biophys Res Commun , vol.414 , pp. 462-467
    • Umenaga, Y.1    Paku, K.S.2    In, Y.3    Ishida, T.4    Tomoo, K.5
  • 228
    • 84896507013 scopus 로고    scopus 로고
    • Cancer cells exploit eIF4E2-directed synthesis of hypoxia response proteins to drive tumor progression
    • Uniacke J, Perera JK, Lachance G, Francisco CB, Lee S (2014) Cancer cells exploit eIF4E2-directed synthesis of hypoxia response proteins to drive tumor progression. Cancer Res 74:1379-1389
    • (2014) Cancer Res , vol.74 , pp. 1379-1389
    • Uniacke, J.1    Perera, J.K.2    Lachance, G.3    Francisco, C.B.4    Lee, S.5
  • 229
    • 33746118057 scopus 로고    scopus 로고
    • Activation of mammalian target of rapamycin signaling pathway contributes to tumor cell survival in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma
    • Vega F, Medeiros LJ, Leventaki V, Atwell C, Cho-Vega JH, Tian L, Claret FX, Rassidakis GZ (2006) Activation of mammalian target of rapamycin signaling pathway contributes to tumor cell survival in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma. Cancer Res 66:6589-6597
    • (2006) Cancer Res , vol.66 , pp. 6589-6597
    • Vega, F.1    Medeiros, L.J.2    Leventaki, V.3    Atwell, C.4    Cho-Vega, J.H.5    Tian, L.6    Claret, F.X.7    Rassidakis, G.Z.8
  • 230
    • 33748192942 scopus 로고    scopus 로고
    • The Myc oncoprotein as a therapeutic target for human cancer
    • Vita M, Henriksson M (2006) The Myc oncoprotein as a therapeutic target for human cancer. Semin Cancer Biol 16:318-330
    • (2006) Semin Cancer Biol , vol.16 , pp. 318-330
    • Vita, M.1    Henriksson, M.2
  • 231
    • 0034730734 scopus 로고    scopus 로고
    • Stabilization of eukaryotic initiation factor 4E binding to the mRNA 5?-Cap by domains of eIF4G
    • von Der Haar T, Ball PD, McCarthy JE (2000) Stabilization of eukaryotic initiation factor 4E binding to the mRNA 5?-Cap by domains of eIF4G. J Biol Chem 275:30551-30555
    • (2000) J Biol Chem , vol.275 , pp. 30551-30555
    • Von Der Haar, T.1    Ball, P.D.2    McCarthy, J.E.3
  • 232
    • 0033736202 scopus 로고    scopus 로고
    • Pronucleotides: Toward the in vivo delivery of antiviral and anticancer nucleotides
    • Wagner CR, Iyer VV, McIntee EJ (2000) Pronucleotides: toward the in vivo delivery of antiviral and anticancer nucleotides. Med Res Rev 20:417-451
    • (2000) Med Res Rev , vol.20 , pp. 417-451
    • Wagner, C.R.1    Iyer, V.V.2    McIntee, E.J.3
  • 233
    • 84870757284 scopus 로고    scopus 로고
    • Tinkering with translation: Protein synthesis in virusinfected cells
    • Walsh D, Mathews MB, Mohr I (2013) Tinkering with translation: protein synthesis in virusinfected cells. Cold Spring Harb Perspect Biol 5:a012351
    • (2013) Cold Spring Harb Perspect Biol , vol.5 , pp. a012351
    • Walsh, D.1    Mathews, M.B.2    Mohr, I.3
  • 234
    • 0033031044 scopus 로고    scopus 로고
    • Expression of the eukaryotic translation initiation factors 4E and 2alpha in non-Hodgkin's lymphomas
    • Wang S, Rosenwald IB, Hutzler MJ, Pihan GA, Savas L, Chen JJ, Woda BA (1999) Expression of the eukaryotic translation initiation factors 4E and 2alpha in non-Hodgkin's lymphomas. Am J Pathol 155:247-255
    • (1999) Am J Pathol , vol.155 , pp. 247-255
    • Wang, S.1    Rosenwald, I.B.2    Hutzler, M.J.3    Pihan, G.A.4    Savas, L.5    Chen, J.J.6    Woda, B.A.7
  • 235
    • 84877821108 scopus 로고    scopus 로고
    • Multiple functions of the RNA-binding protein HuR in cancer progression, treatment responses and prognosis
    • Wang J, Guo Y, Chu H, Guan Y, Bi J, Wang B (2013a) Multiple functions of the RNA-binding protein HuR in cancer progression, treatment responses and prognosis. Int J Mol Sci 14:10015-10041
    • (2013) Int J Mol Sci , vol.14 , pp. 10015-10041
    • Wang, J.1    Guo, Y.2    Chu, H.3    Guan, Y.4    Bi, J.5    Wang, B.6
  • 236
    • 84875218045 scopus 로고    scopus 로고
    • HPV E6 induces eIF4E transcription to promote the proliferation and migration of cervical cancer
    • Wang S, Pang T, Gao M, Kang H, Ding W, Sun X, Zhao Y, Zhu W, Tang X, Yao Y et al. (2013b) HPV E6 induces eIF4E transcription to promote the proliferation and migration of cervical cancer. FEBS Lett 587:690-697
    • (2013) FEBS Lett , vol.587 , pp. 690-697
    • Wang, S.1    Pang, T.2    Gao, M.3    Kang, H.4    Ding, W.5    Sun, X.6    Zhao, Y.7    Zhu, W.8    Tang, X.9    Yao, Y.10
  • 237
    • 84871885080 scopus 로고    scopus 로고
    • Detection of eukaryotic translation initiation factor 4E and its clinical significance in hepatocellular carcinoma
    • Wang XL, Cai HP, Ge JH, Su XF (2012) Detection of eukaryotic translation initiation factor 4E and its clinical significance in hepatocellular carcinoma. World J Gastroenterol 18:2540-2544
    • (2012) World J Gastroenterol , vol.18 , pp. 2540-2544
    • Wang, X.L.1    Cai, H.P.2    Ge, J.H.3    Su, X.F.4
  • 238
    • 0032981328 scopus 로고    scopus 로고
    • Phosphorylation of the cap-binding protein eukaryotic translation initiation factor 4E by protein kinase Mnk1 in vivo
    • Waskiewicz AJ, Johnson JC, Penn B, Mahalingam M, Kimball SR, Cooper JA (1999) Phosphorylation of the cap-binding protein eukaryotic translation initiation factor 4E by protein kinase Mnk1 in vivo. Mol Cell Biol 19:1871-1880
    • (1999) Mol Cell Biol , vol.19 , pp. 1871-1880
    • Waskiewicz, A.J.1    Johnson, J.C.2    Penn, B.3    Mahalingam, M.4    Kimball, S.R.5    Cooper, J.A.6
  • 241
    • 0029560024 scopus 로고
    • Translational upregulation of the c-myc oncogene in Bloom's syndrome cell lines
    • West MJ, Sullivan NF, Willis AE (1995) Translational upregulation of the c-myc oncogene in Bloom's syndrome cell lines. Oncogene 11:2515-2524
    • (1995) Oncogene , vol.11 , pp. 2515-2524
    • West, M.J.1    Sullivan, N.F.2    Willis, A.E.3
  • 242
    • 84871570209 scopus 로고    scopus 로고
    • EIF4E over-expresses and enhances cell proliferation and cell cycle progression in nasopharyngeal carcinoma
    • Wu M, Liu Y, Di X, Kang H, Zeng H, Zhao Y, Cai K, Pang T, Wang S, Yao Y et al. (2013) EIF4E over-expresses and enhances cell proliferation and cell cycle progression in nasopharyngeal carcinoma. Med Oncol 30:400
    • (2013) Med Oncol , vol.30 , pp. 400
    • Wu, M.1    Liu, Y.2    Di, X.3    Kang, H.4    Zeng, H.5    Zhao, Y.6    Cai, K.7    Pang, T.8    Wang, S.9    Yao, Y.10
  • 243
    • 62849126891 scopus 로고    scopus 로고
    • Requirement of RNA binding of mammalian eukaryotic translation initiation factor 4GI (eIF4GI) for efficient interaction of eIF4E with the mRNA cap
    • Yanagiya A, Svitkin YV, Shibata S, Mikami S, Imataka H, Sonenberg N (2009) Requirement of RNA binding of mammalian eukaryotic translation initiation factor 4GI (eIF4GI) for efficient interaction of eIF4E with the mRNA cap. Mol Cell Biol 29:1661-1669
    • (2009) Mol Cell Biol , vol.29 , pp. 1661-1669
    • Yanagiya, A.1    Svitkin, Y.V.2    Shibata, S.3    Mikami, S.4    Imataka, H.5    Sonenberg, N.6
  • 245
    • 33947716942 scopus 로고    scopus 로고
    • Expression levels of eIF4E, VEGF, and cyclin D1, and correlation of eIF4E with VEGF and cyclin D1 in multi-tumor tissue microarray
    • Yang SX, Hewitt SM, Steinberg SM, Liewehr DJ, Swain SM (2007) Expression levels of eIF4E, VEGF, and cyclin D1, and correlation of eIF4E with VEGF and cyclin D1 in multi-tumor tissue microarray. Oncol Rep 17:281-287
    • (2007) Oncol Rep , vol.17 , pp. 281-287
    • Yang, S.X.1    Hewitt, S.M.2    Steinberg, S.M.3    Liewehr, D.J.4    Swain, S.M.5
  • 247
    • 84879574106 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1alpha (HIF-1alpha) promotes cap-dependent translation of selective mRNAs through up-regulating initiation factor eIF4E1 in breast cancer cells under hypoxia conditions
    • Yi T, Papadopoulos E, Hagner PR, Wagner G (2013) Hypoxia-inducible factor-1alpha (HIF-1alpha) promotes cap-dependent translation of selective mRNAs through up-regulating initiation factor eIF4E1 in breast cancer cells under hypoxia conditions. J Biol Chem 288:18732-18742
    • (2013) J Biol Chem , vol.288 , pp. 18732-18742
    • Yi, T.1    Papadopoulos, E.2    Hagner, P.R.3    Wagner, G.4
  • 249
    • 51849111556 scopus 로고    scopus 로고
    • PI3K pathway alterations in cancer: Variations on a theme
    • Yuan TL, Cantley LC (2008) PI3K pathway alterations in cancer: variations on a theme. Oncogene 27:5497-5510
    • (2008) Oncogene , vol.27 , pp. 5497-5510
    • Yuan, T.L.1    Cantley, L.C.2
  • 250
    • 58149213801 scopus 로고    scopus 로고
    • Non-Smad pathways in TGF-beta signaling
    • Zhang YE (2009) Non-Smad pathways in TGF-beta signaling. Cell Res 19:128-139
    • (2009) Cell Res , vol.19 , pp. 128-139
    • Zhang, Y.E.1
  • 251
    • 79953709986 scopus 로고    scopus 로고
    • Targeting the mTOR kinase domain: The second generation of mTOR inhibitors
    • Zhang YJ, Duan Y, Zheng XF (2011) Targeting the mTOR kinase domain: the second generation of mTOR inhibitors. Drug Discov Today 16:325-331
    • (2011) Drug Discov Today , vol.16 , pp. 325-331
    • Zhang, Y.J.1    Duan, Y.2    Zheng, X.F.3
  • 252
    • 36049032764 scopus 로고    scopus 로고
    • Relationship between eukaryotic translation initiation factor 4E and malignant angiogenesis in non-Hodgkin lymphoma
    • 654
    • Zhao Y, Liu W, Zhou S, Zhou J, Sun H (2005) Relationship between eukaryotic translation initiation factor 4E and malignant angiogenesis in non-Hodgkin lymphoma. J Huazhong Univ Sci Technolog Med Sci 25:636-638, 654
    • (2005) J Huazhong Univ Sci Technolog Med Sci , vol.25 , pp. 636-638
    • Zhao, Y.1    Liu, W.2    Zhou, S.3    Zhou, J.4    Sun, H.5
  • 253
    • 6044223545 scopus 로고    scopus 로고
    • Activation of the Akt/mammalian target of rapamycin/4E-BP1 pathway by ErbB2 overexpression predicts tumor progression in breast cancers
    • Zhou X, Tan M, Stone Hawthorne V, Klos KS, Lan KH, Yang Y, Yang W, Smith TL, Shi D, Yu D (2004) Activation of the Akt/mammalian target of rapamycin/4E-BP1 pathway by ErbB2 overexpression predicts tumor progression in breast cancers. Clin Cancer Res 10:6779-6788
    • (2004) Clin Cancer Res , vol.10 , pp. 6779-6788
    • Zhou, X.1    Tan, M.2    Stone Hawthorne, V.3    Klos, K.S.4    Lan, K.H.5    Yang, Y.6    Yang, W.7    Smith, T.L.8    Shi, D.9    Yu, D.10
  • 254
    • 33749985730 scopus 로고    scopus 로고
    • Eukaryotic initiation factor 4E (eIF4E) and angiogenesis: Prognostic markers for breast cancer
    • Zhou S, Wang GP, Liu C, Zhou M (2006) Eukaryotic initiation factor 4E (eIF4E) and angiogenesis: prognostic markers for breast cancer. BMC Cancer 6:231
    • (2006) BMC Cancer , vol.6 , pp. 231
    • Zhou, S.1    Wang, G.P.2    Liu, C.3    Zhou, M.4
  • 255
    • 79959236276 scopus 로고    scopus 로고
    • Knockdown of eIF4E suppresses cell growth and migration, enhances chemosensitivity and correlates with increase in Bax/Bcl-2 ratio in triple-negative breast cancer cells
    • Zhou FF, Yan M, Guo GF, Wang F, Qiu HJ, Zheng FM, Zhang Y, Liu Q, Zhu XF, Xia LP (2011) Knockdown of eIF4E suppresses cell growth and migration, enhances chemosensitivity and correlates with increase in Bax/Bcl-2 ratio in triple-negative breast cancer cells. Med Oncol 28:1302-1307
    • (2011) Med Oncol , vol.28 , pp. 1302-1307
    • Zhou, F.F.1    Yan, M.2    Guo, G.F.3    Wang, F.4    Qiu, H.J.5    Zheng, F.M.6    Zhang, Y.7    Liu, Q.8    Zhu, X.F.9    Xia, L.P.10
  • 256
    • 24044529785 scopus 로고    scopus 로고
    • Transcriptional repression of the eukaryotic initiation factor 4E gene by wild type p53
    • Zhu N, Gu L, Findley HW, Zhou M (2005) Transcriptional repression of the eukaryotic initiation factor 4E gene by wild type p53. Biochem Biophys Res Commun 335:1272-1279
    • (2005) Biochem Biophys Res Commun , vol.335 , pp. 1272-1279
    • Zhu, N.1    Gu, L.2    Findley, H.W.3    Zhou, M.4
  • 257
    • 79958836140 scopus 로고    scopus 로고
    • Formation of the eIF4F translation-initiation complex determines sensitivity to anticancer drugs targeting the EGFR and HER2 receptors
    • Zindy P, Berge Y, Allal B, Filleron T, Pierredon S, Cammas A, Beck S, Mhamdi L, Fan L, Favre G et al. (2011) Formation of the eIF4F translation-initiation complex determines sensitivity to anticancer drugs targeting the EGFR and HER2 receptors. Cancer Res 71:4068-4073
    • (2011) Cancer Res , vol.71 , pp. 4068-4073
    • Zindy, P.1    Berge, Y.2    Allal, B.3    Filleron, T.4    Pierredon, S.5    Cammas, A.6    Beck, S.7    Mhamdi, L.8    Fan, L.9    Favre, G.10
  • 258
    • 0037273418 scopus 로고    scopus 로고
    • Phosphorylation of eIF4E attenuates its interaction with mRNA 5? cap analogs by electrostatic repulsion: Intein-mediated protein ligation strategy to obtain phosphorylated protein
    • Zuberek J, Wyslouch-Cieszynska A, Niedzwiecka A, Dadlez M, Stepinski J, Augustyniak W, Gingras AC, Zhang Z, Burley SK, Sonenberg N et al. (2003) Phosphorylation of eIF4E attenuates its interaction with mRNA 5? cap analogs by electrostatic repulsion: intein-mediated protein ligation strategy to obtain phosphorylated protein. RNA 9:52-61
    • (2003) RNA , vol.9 , pp. 52-61
    • Zuberek, J.1    Wyslouch-Cieszynska, A.2    Niedzwiecka, A.3    Dadlez, M.4    Stepinski, J.5    Augustyniak, W.6    Gingras, A.C.7    Zhang, Z.8    Burley, S.K.9    Sonenberg, N.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.