hnRNP K binds a core polypyrimidine element in the eukaryotic translation initiation factor 4E (eIF4E) promoter, and its regulation of eIF4E contributes to neoplastic transformation

Molecular and Cellular Biology

Volumn 25, Issue 15, 2005, Pages 6436-6453

  Lynch, Mary ^a   Chen, Li ^a   Ravitz, Michael J ^a   Mehtani, Sapna ^a   Korenblat, Kevin ^b   Pazin, Michael J ^c   Schmidt, Emmett V ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; CAPPED RNA; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN K; INITIATION FACTOR 4E; MESSENGER RNA; TATA BINDING PROTEIN; TRANSCRIPTION FACTOR;

AFFINITY CHROMATOGRAPHY; ARTICLE; CELL CYCLE G1 PHASE; CELL DIVISION; CELL PROLIFERATION; CELL TRANSFORMATION; CONTROLLED STUDY; CORE POLYPYRIMIDINE ELEMENT; DNA FLANKING REGION; DNA STRUCTURE; GENE OVEREXPRESSION; GROWTH REGULATION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; NEOPLASM; NONHUMAN; ONCOGENE C MYC; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; PROTEIN PROTEIN INTERACTION; REPORTER GENE; RNA INTERFERENCE; RNA SPLICING; RNA TRANSPORT; TATA BOX; TRANSCRIPTION REGULATION; TRANSLATION INITIATION;

ANIMALS; BASE SEQUENCE; BINDING SITES; CELL TRANSFORMATION, NEOPLASTIC; EUKARYOTIC INITIATION FACTOR-4E; GENE EXPRESSION REGULATION, NEOPLASTIC; HELA CELLS; HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEIN K; HUMANS; MICE; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); RATS; TATA BOX; TRANSCRIPTION, GENETIC;

EUKARYOTA;

EID: 22544464680     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.25.15.6436-6453.2005     Document Type: Article

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