Oncogenic activation of MEK/ERK primes melanoma cells for adaptation to endoplasmic reticulum stress

Journal of Investigative Dermatology

Volumn 134, Issue 2, 2014, Pages 488-497

  Croft, Amanda ^a,b   Tay, Kwang H ^a   Boyd, Suzanah C ^c   Guo, Su T ^d   Jiang, Chen C ^a   Lai, Fritz ^a   Tseng, Hsin Yi ^a   Jin, Lei ^a   Rizos, Helen ^c   Hersey, Peter ^e   Zhang, Xu D ^a  

^a UNIVERSITY OF NEWCASTLE   (Australia)

^b CALVARY MATER NEWCASTLE HOSPITAL   (Australia)

^c WESTMEAD HOSPITAL   (Australia)

^d SHANXI CANCER HOSPITAL   (China)

^e UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; ACTIVATING TRANSCRIPTION FACTOR 6; ADENOSINE TRIPHOSPHATASE INHIBITOR; B RAF KINASE; DABRAFENIB; GLUCOSE REGULATED PROTEIN 78; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; INITIATION FACTOR 4E; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE; N [3 (5 CHLORO 1H PYRROLO[2,3 B]PYRIDINE 3 CARBONYL) 2,4 DIFLUOROPHENYL]PROPANESULFONAMIDE; PROTEIN IRE1; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; SMALL INTERFERING RNA; THAPASIGARGIN; TUNICAMYCIN; UNCLASSIFIED DRUG; VEMURAFENIB; X BOX BINDING PROTEIN 1;

ADAPTATION; APOPTOSIS; ARTICLE; CARCINOGENICITY; CELL PROLIFERATION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME INHIBITION; GENE SILENCING; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; MELANOCYTE; MELANOMA; MELANOMA CELL; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; UNFOLDED PROTEIN RESPONSE; WESTERN BLOTTING; WILD TYPE;

ACTIVATING TRANSCRIPTION FACTOR 6; ADAPTATION, PHYSIOLOGICAL; APOPTOSIS; CELL LINE, TUMOR; CELL SURVIVAL; DNA-BINDING PROTEINS; ENDOPLASMIC RETICULUM STRESS; ENDORIBONUCLEASES; HEAT-SHOCK PROTEINS; HUMANS; INDOLES; MAP KINASE SIGNALING SYSTEM; MELANOCYTES; MELANOMA; MEMBRANE PROTEINS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS B-RAF; SKIN NEOPLASMS; SULFONAMIDES; TRANSCRIPTION FACTORS;

EID: 84892832968     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2013.325     Document Type: Article

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