Expression of the eukaryotic translation initiation factors 4E and 2α in non-Hodgkin's lymphomas

American Journal of Pathology

Volumn 155, Issue 1, 1999, Pages 247-255

  Wang, Songtao ^a   Rosenwald, Igor B ^a,b   Hutzler, Michael J ^a   Pihan, German A ^a   Savas, Lou ^a   Chen, Jane Jane ^b   Woda, Bruce A ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INITIATION FACTOR 2; INITIATION FACTOR 4E;

ARTICLE; CANCER GRADING; CARCINOGENESIS; CELL PROLIFERATION; CONTROLLED STUDY; GERMINAL CENTER; HUMAN; HUMAN TISSUE; LYMPH NODE; LYMPHOCYTIC INFILTRATION; LYMPHOCYTOMA; MAJOR CLINICAL STUDY; MANTLE CELL LYMPHOMA; NONHODGKIN LYMPHOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; TRANSLATION INITIATION;

EID: 0033031044     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)65118-8     Document Type: Article

References (43)

1. Brooks RF: Continuous protein synthesis is required to maintain the probability of entry in S phase. Cell 1977, 12:311-317
2. Epifanova OI: Mechanisms underlying the differential sensitivity of proliferating and resting cells to external factors. Int Rev Cytol 1977, 5:303-335
3. Pardee AB, Dubrow R, Hamlin JL, Kletzien RF: Animal cell cycle. Ann Rev Biochem 1978, 47:715-750
4. Sonenberg N: mRNA 5′ cap-binding protein elF4E and control of cell growth. Translational Control. Edited by Hershey JWB, Mathews MB, Sonenberg N. Cold Spring Harbor, NY, Cold Spring Harbor Laboratory Press, 1996, pp 245-269
5. Morris DR: Growth control of translation in mammalian cells. Prog Nucleic Acid Res Mol Biol 1995, 51:339-363
6. Cohen RB, Boal TR, Safer B: Increased elF-2 expression in mitogen-activated primary T-lymphocytes. EMBO J 1990, 9:3831-3837
7. Mao X, Green JM, Safer B, Lindsten T, Frederickson RM, Miyamoto S, Sonenberg N, Thompson CB: Regulation of translation initiation factor gene expression during human T cell activation. J Biol Chem 1992, 267:20444-20450
8. Rosenwald IB, Rhoads DB, Callanan L, Isselbacher KJ, Schmidt EV: Increased expression of eukaryotic translation initiation factors elF-4E and elF-2α in response to growth induction by c-myc. Proc Natl Acad Sci USA 1993, 90:6175-6178
9. Rosenwald IB, Lazaris-Karatzas A, Sonenberg N, Schmidt EV: Elevated expression of cyclin Dl in response to increases in initiation factor elF-4E. Mol Cell Biol 1993, 13:7358-7363
10. Rosenwald IB, Kaspar R, Rousseau D, Gehrke L, LeBoulch P, Chen J-J, Schmidt EV, Sonenberg N, London IM: Eukaryotic translation initiation factor 4E regulates expression of cyclin Dl at transcriptional and post-transcriptional levels. J Biol Chem 1995, 270:21176-21180
11. Trachsel H: Binding of initiator methyionyl-tRNA to ribosomes. Translational Control. Edited by Hershey JWB, Mathews MB, Sonenberg N. Cold Spring Harbor, NY, Cold Spring Harbor Laboratory Press, 1996, pp 113-139
12. Rosenwald IB: Growth factor-independent expression of the gene encoding translation initiation factor 4E in transformed cell lines. Cancer Lett 1995, 98:77-82
13. Rosenwald IB: Upregulated expression of the genes encoding translation initiation factors elF-4E and elF-2α in transformed cells. Cancer Lett 1996, 102:113-123
14. Rosenwald IB: Deregulation of protein synthesis as a mechanism of neoplastic transformation. BioEssays 1996, 18:243-249
15. Lazaris-Karatzas A, Montine KS, Sonenberg N: Malignant transformation by an eukaryotic initiation factor subunit that binds to mRNA 5′ cap. Nature 1990, 345:544-547
16. De Benedetti A, Rhoads RE: Overexpression of eukaryotic protein synthesis initiation factor 4E in HeLa cells results in aberrant growth and morphology. Proc Natl Acad Sci USA 1990, 87:8212-8216
17. Donze O, Jagus R, Koromilas AE, Hershey JWB, Sonenberg N: Abrogation of translation initiation factor elF-2 phosphorylation causes malignant transformation of NIH 3T3 cells. EMBO J 1995, 14:3828-3834
18. Kadin ME, Berard CW, Nanba K, Wasaka H: Lymphoproliferative diseases in Japan and Western countries. Hum Pathol 1983, 14:745-772
19. Jones RM, Branda J, Johnston KA, Polymenis M, Gadd M, Rustgi A, Callanan L, Schmidt EV: An essential E box in the promoter of the gene encoding mRNA cap-binding protein (eukaryotic initiation factor 4E) is a target for activation by c-myc. Mol Cell Biol 1996, 16:4754-4764
20. Pileri SA, Leoncini L, Falini B: Revised European-American Lymphoma Classification, Curr Opin Oncol 1995, 7:401-407
21. Rosenwald IB, Chen J-J, Wang S, Savas L, London IM, Pullman J: Upregulation of protein synthesis initiation factor elF-4E is an early event during colon carcinogenesis. Oncogene, 1999, 18:2507-2517
22. Scorsone KA, Paniers R, Rowland AG, Henshaw EC: Phosphorylation of eukaryotic initiation factor 2 during physiological stresses which affect protein synthesis. J Biol Chem 1987, 262:14538-14543
23. Siegel S, Castellan NJ: Nonparametric Statistics for the Behavioral Sciences. Boston, McGraw-Hill, 1997 pp 128-137, 135-244
24. Braylan RC, Diamond LW, Powell ML, Harty-Golder B: Percentage of cells in the S phase of the cell cycle in human lymphoma determined by flow cytometry. Cytometry 1980, 1(3):171-174
25. Strauchen JA, May MM, Crown J: Large cell transformation of subclinical small lymphocytic leukemia/lymphoma: a variant of Richter's syndrome. Hematol Oncol 1987, 5:167-174
26. Withers DA, Harvey RC, Faust JB, Melnyk O, Carey K, Meeker TC: Characterization of a candidate bcl-1 gene. Mol Cell Biol 1991, 11: 4846-4853
27. Subar M, Neri A, Inghirami G, Knowles DM, Dalla-Favera R: Frequent c-myc oncogene activation and infrequent presence of Epstein-Barr virus genome in AIDS-associated lymphoma. Blood 1988, 72:667-671
28. Van Krieken JHJM, Medeiros LJ, Pals ST, Raffeld M Kluin PM: Diffuse aggressive B-cell lymphomas of the gastrointestinal tract: an immunophenotypic and gene rearrangement analysis of 22 cases. Am J Clin Pathol 1992, 97:170-178
29. Medeiros LJ, Bagg A, Cossman J: Molecular genetics in the diagnosis and classification of lymphoid neoplasms. Surgical Pathology of the Lymph Nodes and Related Organs, ed 2. Edited by Jaffe ES. Philadelphia, Saunders, 1995, pp 58-97
30. Locker J, Nalesnik M: Molecular genetic analysis of lymphoid tumors arising from organ transplantation. Am J Pathol 1989, 135:977-987
31. De Benedetti A, Joshi B, Graff JR, Zimmer SG: CHO cells transformed by the initiation factor elF-4E display increased c-myc expression but require overexpression of Max for tumorigenicity. Mol Cell Differ 1994, 2:347-371
32. Shantz LM, Hu R-H, Pegg AE: Regulation of ornithine decarboxylase in a transformed cell line that overexpresses translation initiation factor elF-4E. Cancer Res 1996, 56:3265-3269
33. Kevil K, Carter P, Hu B, De Benedetti A: Translational enhancement of FGF-2 by elF-4 factors and alternate utilization of CUG and AUG codons for translation initiation. Oncogene 1995, 11:2339-2348
34. Kevil CG, De Benedetti A, Payne DK, Coe LL, Laroux FS, Alexander JS: Translational regulation of vascular permeability factor by eukaryotic initiation factor 4E: implications for tumor angiogenesis. Int J Cancer 1996, 65:785-790
35. Graff JR, Boghaert ER, De Benedetti A, Tudor DL, Zimmer CC, Chan SK, Zimmer SG: Reduction of translation initiation factor 4E decreases the malignancy of ras-transformed cloned rat embryo fibroblasts. Int J Cancer 1995, 60:255-263
36. Polunovsky VA, Rosenwald IB, Thurik AT, White J, Chiang L, Sonenberg N, Bitterman PB: Translational control of programmed cell death: initiation factor 4E blocks apoptosis in growth factor restricted fibroblasts with physiologically expressed or deregulated Myc. Mol Cell Biol 1996, 16:6573-6581
37. Hanash SM, Beretta L, Bacroft CL, Sheldon S, Glover TW, Ungar D, Sonenberg N: Mapping of the gene for interferon-inducible dsRNA-dependent protein kinase to chromosome region 2p21-22: a site of rearrangements in myeloproliferative disorders. Genes Chromosomes &Cancer 1993, 3:34-37
38. Beretta L, Gabbay M, Berger R, Hanash SM, Sonenberg N: Expression of the protein kinase PKR is modulated by IRF-1 and is reduced in 5q-associated eukemias. Oncogene 1996, 12:1593-1596
39. Lu D, Yunis JJ: Cloning, expression, and localization of an RNA helicase gene from a human lymphoid cell line with chromosomal breakpoint 11q23.3. Nucleic Acid Res 1992, 20:1967-1972
40. Seto M, Yamamoto K, Takahashi T, Ueda R: Cloning and expression of a murine cDNA homologous to the human RCK/p54, a lymphoma-linked chromosomal translocation junction gene on 11q23. Gene 1995 166:293-296
41. Arai Y, Hosoda F, Kobayashi H, Arai K, Hayashi Y, Kamada N, Kaneko Y, Ohki M: The inv(11)(p15q22) chromosome translocation of de novo and therapy-related myeloid malignancies results in fusion of the nucleoporin gene, NUP98, with the putative RNA helicase gene, DDX10. Blood 1997, 89:3936-3944
42. Li BDL, Liu L, Dawson M, De Benedetti A: Overexpression of eukaryotic initiation factor 4E (elF-4E) in breast carcinoma. Cancer 1997, 79:2385-2390
43. Nathan C-AO, Liu L, Li BDL, Abreo FW, Nandy I, DeBenedetti A: Detection of the proto-oncogene elF-4E in surgical margins may predict recurrence in head and neck cancer. Oncogene 1997, 15: 579-584