-
1
-
-
84880794274
-
Unravelling stem cell dynamics by lineage tracing
-
Blanpain C, &, Simons BD, (2013) Unravelling stem cell dynamics by lineage tracing. Nat Rev Mol Cell Biol 14, 489-502.
-
(2013)
Nat Rev Mol Cell Biol
, vol.14
, pp. 489-502
-
-
Blanpain, C.1
Simons, B.D.2
-
2
-
-
75749146169
-
Coexistence of quiescent and active adult stem cells in mammals
-
Li L, &, Clevers H, (2010) Coexistence of quiescent and active adult stem cells in mammals. Science 327, 542-545.
-
(2010)
Science
, vol.327
, pp. 542-545
-
-
Li, L.1
Clevers, H.2
-
3
-
-
84886283477
-
Regenerating the skin: a task for the heterogeneous stem cell pool and surrounding niche
-
Solanas G, &, Benitah SA, (2013) Regenerating the skin: a task for the heterogeneous stem cell pool and surrounding niche. Nat Rev Mol Cell Biol 14, 737-748.
-
(2013)
Nat Rev Mol Cell Biol
, vol.14
, pp. 737-748
-
-
Solanas, G.1
Benitah, S.A.2
-
4
-
-
84894267586
-
In situ identification of bipotent stem cells in the mammary gland
-
Rios AC, Fu NY, Lindeman GJ, &, Visvader JE, (2015) In situ identification of bipotent stem cells in the mammary gland. Nature 506, 322-327.
-
(2015)
Nature
, vol.506
, pp. 322-327
-
-
Rios, A.C.1
Fu, N.Y.2
Lindeman, G.J.3
Visvader, J.E.4
-
5
-
-
84879796428
-
The Touch dome defines an epidermal niche specialized for mechanosensory signaling
-
Doucet YS, Woo S-H, Ruiz ME, &, Owens DM, (2013) The Touch dome defines an epidermal niche specialized for mechanosensory signaling. Cell Rep 3, 1759-1765.
-
(2013)
Cell Rep
, vol.3
, pp. 1759-1765
-
-
Doucet, Y.S.1
Woo, S.-H.2
Ruiz, M.E.3
Owens, D.M.4
-
6
-
-
80855130470
-
Distinct stem cells contribute to mammary gland development and maintenance
-
Van Keymeulen A, Rocha AS, Ousset M, Beck B, Bouvencourt G, Rock J, Sharma N, Dekoninck S, &, Blanpain C, (2012) Distinct stem cells contribute to mammary gland development and maintenance. Nature 479, 189-193.
-
(2012)
Nature
, vol.479
, pp. 189-193
-
-
Van Keymeulen, A.1
Rocha, A.S.2
Ousset, M.3
Beck, B.4
Bouvencourt, G.5
Rock, J.6
Sharma, N.7
Dekoninck, S.8
Blanpain, C.9
-
7
-
-
84886994729
-
Perspective
-
Gage FH, &, Temple S, (2013) Perspective. Neuron 80, 588-601.
-
(2013)
Neuron
, vol.80
, pp. 588-601
-
-
Gage, F.H.1
Temple, S.2
-
8
-
-
33847032960
-
The mammalian epigenome
-
Bernstein BE, Meissner A, &, Lander ES, (2007) The mammalian epigenome. Cell 128, 669-681.
-
(2007)
Cell
, vol.128
, pp. 669-681
-
-
Bernstein, B.E.1
Meissner, A.2
Lander, E.S.3
-
9
-
-
77956222562
-
Polycomb group proteins: multi-faceted regulators of somatic stem cells and cancer
-
Sauvageau M, &, Sauvageau G, (2010) Polycomb group proteins: multi-faceted regulators of somatic stem cells and cancer. Cell Stem Cell 7, 299-313.
-
(2010)
Cell Stem Cell
, vol.7
, pp. 299-313
-
-
Sauvageau, M.1
Sauvageau, G.2
-
10
-
-
84863610549
-
Polycomb in stem cells: PRC1 branches out
-
Luis NM, Morey L, Di Croce L, &, Benitah SA, (2012) Polycomb in stem cells: PRC1 branches out. Cell Stem Cell 11, 16-21.
-
(2012)
Cell Stem Cell
, vol.11
, pp. 16-21
-
-
Luis, N.M.1
Morey, L.2
Di Croce, L.3
Benitah, S.A.4
-
11
-
-
80053427396
-
Roles of the polycomb group proteins in stem cells and cancer
-
Richly H, Aloia L, &, Di Croce L, (2011) Roles of the polycomb group proteins in stem cells and cancer. Cell Death Dis 2, e204-e207.
-
(2011)
Cell Death Dis
, vol.2
, pp. e204-e207
-
-
Richly, H.1
Aloia, L.2
Di Croce, L.3
-
12
-
-
33845799903
-
Polycomb silencing mechanisms and the management of genomic programmes
-
Schwartz YB, &, Pirrotta V, (2007) Polycomb silencing mechanisms and the management of genomic programmes. Nat Rev Genet 8, 9-22.
-
(2007)
Nat Rev Genet
, vol.8
, pp. 9-22
-
-
Schwartz, Y.B.1
Pirrotta, V.2
-
13
-
-
77956202054
-
Polycomb group proteins set the stage for early lineage commitment
-
Surface LE, Thornton SR, &, Boyer LA, (2010) Polycomb group proteins set the stage for early lineage commitment. Cell Stem Cell 7, 288-298.
-
(2010)
Cell Stem Cell
, vol.7
, pp. 288-298
-
-
Surface, L.E.1
Thornton, S.R.2
Boyer, L.A.3
-
14
-
-
84892685799
-
Zrf1 is required to establish and maintain neural progenitor identity
-
Aloia L, Di Stefano B, Sessa A, Morey L, Santanach A, Gutierrez A, Cozzuto L, Benitah SA, Graf T, Broccoli V, et al,. (2014) Zrf1 is required to establish and maintain neural progenitor identity. Genes Dev 28, 182-197.
-
(2014)
Genes Dev
, vol.28
, pp. 182-197
-
-
Aloia, L.1
Di Stefano, B.2
Sessa, A.3
Morey, L.4
Santanach, A.5
Gutierrez, A.6
Cozzuto, L.7
Benitah, S.A.8
Graf, T.9
Broccoli, V.10
-
15
-
-
84876871047
-
Occupying chromatin: polycomb mechanisms for getting to genomic targets, stopping transcriptional traffic, and staying put
-
Simon JA, &, Kingston RE, (2013) Occupying chromatin: polycomb mechanisms for getting to genomic targets, stopping transcriptional traffic, and staying put. Mol Cell 49, 808-824.
-
(2013)
Mol Cell
, vol.49
, pp. 808-824
-
-
Simon, J.A.1
Kingston, R.E.2
-
16
-
-
84902127230
-
Variant PRC1 complex-dependent H2A ubiquitylation drives PRC2 recruitment and polycomb domain formation
-
Blackledge NP, Farcas AM, Kondo T, King HW, McGouran JF, Hanssen LLP, Ito S, Cooper S, Kondo K, Koseki Y, et al,. (2014) Variant PRC1 complex-dependent H2A ubiquitylation drives PRC2 recruitment and polycomb domain formation. Cell 157, 1445-1459.
-
(2014)
Cell
, vol.157
, pp. 1445-1459
-
-
Blackledge, N.P.1
Farcas, A.M.2
Kondo, T.3
King, H.W.4
McGouran, J.F.5
Hanssen, L.L.P.6
Ito, S.7
Cooper, S.8
Kondo, K.9
Koseki, Y.10
-
17
-
-
84855516244
-
Nonoverlapping functions of the polycomb group Cbx family of proteins in embryonic stem cells
-
Morey L, Pascual G, Cozzuto L, Roma G, Wutz A, Benitah SA, &, Di Croce L, (2012) Nonoverlapping functions of the polycomb group Cbx family of proteins in embryonic stem cells. Cell Stem Cell 10, 47-62.
-
(2012)
Cell Stem Cell
, vol.10
, pp. 47-62
-
-
Morey, L.1
Pascual, G.2
Cozzuto, L.3
Roma, G.4
Wutz, A.5
Benitah, S.A.6
Di Croce, L.7
-
18
-
-
84873167174
-
RYBP and Cbx7 define specific biological functions of polycomb complexes in mouse embryonic stem cells
-
Morey L, Aloia L, Cozzuto L, Benitah SA, &, Di Croce L, (2013) RYBP and Cbx7 define specific biological functions of polycomb complexes in mouse embryonic stem cells. Cell Rep 3, 60-69.
-
(2013)
Cell Rep
, vol.3
, pp. 60-69
-
-
Morey, L.1
Aloia, L.2
Cozzuto, L.3
Benitah, S.A.4
Di Croce, L.5
-
19
-
-
84862908896
-
MicroRNA regulation of Cbx7 mediates a switch of polycomb orthologs during ESC differentiation
-
O'Loghlen A, Muñoz-Cabello AM, Gaspar-Maia A, Wu H-A, Banito A, Kunowska N, Racek T, Pemberton HN, Beolchi P, Lavial F, et al,. (2012) MicroRNA regulation of Cbx7 mediates a switch of polycomb orthologs during ESC differentiation. Cell Stem Cell 10, 33-46.
-
(2012)
Cell Stem Cell
, vol.10
, pp. 33-46
-
-
O'Loghlen, A.1
Muñoz-Cabello, A.M.2
Gaspar-Maia, A.3
Wu, H.-A.4
Banito, A.5
Kunowska, N.6
Racek, T.7
Pemberton, H.N.8
Beolchi, P.9
Lavial, F.10
-
20
-
-
84902333500
-
Targeting polycomb to pericentric heterochromatin in embryonic stem cells reveals a role for H2AK119u1 in PRC2 recruitment
-
Cooper S, Dienstbier M, Hassan R, Schermelleh L, Sharif J, Blackledge NP, De Marco V, Elderkin S, Koseki H, Klose R, et al,. (2014) Targeting polycomb to pericentric heterochromatin in embryonic stem cells reveals a role for H2AK119u1 in PRC2 recruitment. Cell Rep 7, 1456-1470.
-
(2014)
Cell Rep
, vol.7
, pp. 1456-1470
-
-
Cooper, S.1
Dienstbier, M.2
Hassan, R.3
Schermelleh, L.4
Sharif, J.5
Blackledge, N.P.6
De Marco, V.7
Elderkin, S.8
Koseki, H.9
Klose, R.10
-
21
-
-
84856237597
-
Polycomb protein Ezh1 promotes RNA polymerase II elongation
-
Mousavi K, Zare H, Wang AH, &, Sartorelli V, (2012) Polycomb protein Ezh1 promotes RNA polymerase II elongation. Mol Cell 45, 255-262.
-
(2012)
Mol Cell
, vol.45
, pp. 255-262
-
-
Mousavi, K.1
Zare, H.2
Wang, A.H.3
Sartorelli, V.4
-
22
-
-
59149083658
-
Large histone H3 lysine 9 dimethylated chromatin blocks distinguish differentiated from embryonic stem cells
-
Wen B, Wu H, Shinkai Y, Irizarry RA, &, Feinberg AP, (2009) Large histone H3 lysine 9 dimethylated chromatin blocks distinguish differentiated from embryonic stem cells. Nat Genet 41, 246-250.
-
(2009)
Nat Genet
, vol.41
, pp. 246-250
-
-
Wen, B.1
Wu, H.2
Shinkai, Y.3
Irizarry, R.A.4
Feinberg, A.P.5
-
23
-
-
0037099413
-
G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis
-
Tachibana M, (2002) G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis. Genes Dev 16, 1779-1791.
-
(2002)
Genes Dev
, vol.16
, pp. 1779-1791
-
-
Tachibana, M.1
-
24
-
-
81855212627
-
Trithorax group proteins: switching genes on and keeping them active
-
Schuettengruber B, Martinez A-M, Iovino N, &, Cavalli G, (2011) Trithorax group proteins: switching genes on and keeping them active. Nat Rev Mol Cell Biol 12, 799-814.
-
(2011)
Nat Rev Mol Cell Biol
, vol.12
, pp. 799-814
-
-
Schuettengruber, B.1
Martinez, A.-M.2
Iovino, N.3
Cavalli, G.4
-
25
-
-
79951516056
-
A unique chromatin signature uncovers early developmental enhancers in humans
-
Rada-Iglesias A, Bajpai R, Swigut T, Brugmann SA, Flynn RA, &, Wysocka J, (2012) A unique chromatin signature uncovers early developmental enhancers in humans. Nature 470, 279-283.
-
(2012)
Nature
, vol.470
, pp. 279-283
-
-
Rada-Iglesias, A.1
Bajpai, R.2
Swigut, T.3
Brugmann, S.A.4
Flynn, R.A.5
Wysocka, J.6
-
26
-
-
34548413178
-
MLL has a critical role in fetal and adult hematopoietic stem cell self-renewal
-
McMahon KA, Hiew SYL, Hadjur S, Veiga-Fernandes H, Menzel U, Price AJ, Kioussis D, Williams O, &, Brady HJM, (2007) MLL has a critical role in fetal and adult hematopoietic stem cell self-renewal. Cell Stem Cell 1, 338-345.
-
(2007)
Cell Stem Cell
, vol.1
, pp. 338-345
-
-
McMahon, K.A.1
Hiew, S.Y.L.2
Hadjur, S.3
Veiga-Fernandes, H.4
Menzel, U.5
Price, A.J.6
Kioussis, D.7
Williams, O.8
Brady, H.J.M.9
-
27
-
-
77956095231
-
Active DNA demethylation: many roads lead to Rome
-
Wu SC, &, Zhang Y, (2010) Active DNA demethylation: many roads lead to Rome. Nat Rev Mol Cell Biol 11, 607-620.
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, pp. 607-620
-
-
Wu, S.C.1
Zhang, Y.2
-
28
-
-
84892763878
-
Reversing DNA methylation: mechanisms, genomics, and biological functions
-
Wu H, &, Zhang Y, (2014) Reversing DNA methylation: mechanisms, genomics, and biological functions. Cell 156, 45-68.
-
(2014)
Cell
, vol.156
, pp. 45-68
-
-
Wu, H.1
Zhang, Y.2
-
29
-
-
84871702441
-
The dynamics of genome-wide DNA methylation reprogramming in mouse primordial germ cells
-
Seisenberger S, Andrews S, Krueger F, Arand J, Walter J, Santos F, Popp C, Thienpont B, Dean W, &, Reik W, (2012) The dynamics of genome-wide DNA methylation reprogramming in mouse primordial germ cells. Mol Cell 48, 849-862.
-
(2012)
Mol Cell
, vol.48
, pp. 849-862
-
-
Seisenberger, S.1
Andrews, S.2
Krueger, F.3
Arand, J.4
Walter, J.5
Santos, F.6
Popp, C.7
Thienpont, B.8
Dean, W.9
Reik, W.10
-
30
-
-
0036803302
-
Stage- and cell-specific expression of Dnmt3a and Dnmt3b during embryogenesis
-
Watanabe D, Suetake I, Tada T, &, Tajima S, (2002) Stage- and cell-specific expression of Dnmt3a and Dnmt3b during embryogenesis. Mech Dev 118, 187-190.
-
(2002)
Mech Dev
, vol.118
, pp. 187-190
-
-
Watanabe, D.1
Suetake, I.2
Tada, T.3
Tajima, S.4
-
31
-
-
0033615717
-
DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
-
Okano M, Bell DW, Haber DA, &, Li E, (1999) DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 99, 247-257.
-
(1999)
Cell
, vol.99
, pp. 247-257
-
-
Okano, M.1
Bell, D.W.2
Haber, D.A.3
Li, E.4
-
32
-
-
84884827480
-
Dnmt3L antagonizes DNA methylation at bivalent promoters and favors DNA methylation at gene bodies in ESCs
-
Neri F, Krepelova A, Incarnato D, Maldotti M, Parlato C, Galvagni F, Matarese F, Stunnenberg HG, &, Oliviero S, (2013) Dnmt3L antagonizes DNA methylation at bivalent promoters and favors DNA methylation at gene bodies in ESCs. Cell 155, 121-134.
-
(2013)
Cell
, vol.155
, pp. 121-134
-
-
Neri, F.1
Krepelova, A.2
Incarnato, D.3
Maldotti, M.4
Parlato, C.5
Galvagni, F.6
Matarese, F.7
Stunnenberg, H.G.8
Oliviero, S.9
-
33
-
-
33947317206
-
The epigenetic regulation of mammalian telomeres
-
Blasco MA, (2007) The epigenetic regulation of mammalian telomeres. Nat Rev Genet 8, 299-309.
-
(2007)
Nat Rev Genet
, vol.8
, pp. 299-309
-
-
Blasco, M.A.1
-
34
-
-
33645702660
-
DNA methyltransferases control telomere length and telomere recombination in mammalian cells
-
Gonzalo S, Jaco I, Fraga MF, Chen T, Li E, Esteller M, &, Blasco MA, (2006) DNA methyltransferases control telomere length and telomere recombination in mammalian cells. Nat Cell Biol 8, 416-424.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 416-424
-
-
Gonzalo, S.1
Jaco, I.2
Fraga, M.F.3
Chen, T.4
Li, E.5
Esteller, M.6
Blasco, M.A.7
-
35
-
-
0036144048
-
DNA methylation patterns and epigenetic memory
-
Bird A, (2002) DNA methylation patterns and epigenetic memory. Genes Dev 16, 6-21.
-
(2002)
Genes Dev
, vol.16
, pp. 6-21
-
-
Bird, A.1
-
36
-
-
84865369147
-
DNA methylation dynamics during in vivo differentiation of blood and skin stem cells
-
Bock C, Beerman I, Lien W-H, Smith ZD, Gu H, Boyle P, Gnirke A, Fuchs E, Rossi DJ, &, Meissner A, (2012) DNA methylation dynamics during in vivo differentiation of blood and skin stem cells. Mol Cell 47, 633-647.
-
(2012)
Mol Cell
, vol.47
, pp. 633-647
-
-
Bock, C.1
Beerman, I.2
Lien, W.-H.3
Smith, Z.D.4
Gu, H.5
Boyle, P.6
Gnirke, A.7
Fuchs, E.8
Rossi, D.J.9
Meissner, A.10
-
37
-
-
84878248139
-
DNA methylation dynamics during intestinal stem cell differentiation reveals enhancers driving gene expression in the villus
-
Kaaij LT, van de Wetering M, Fang F, Decato B, Molaro A, van de Werken HJ, van Es JH, Schuijers J, de Wit E, de Laat W, et al,. (2013) DNA methylation dynamics during intestinal stem cell differentiation reveals enhancers driving gene expression in the villus. Genome Biol 14, R50.
-
(2013)
Genome Biol
, vol.14
, pp. R50
-
-
Kaaij, L.T.1
Van De Wetering, M.2
Fang, F.3
Decato, B.4
Molaro, A.5
Van De Werken, H.J.6
Van Es, J.H.7
Schuijers, J.8
De Wit, E.9
De Laat, W.10
-
38
-
-
36849072573
-
The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA
-
Sharif J, Muto M, Takebayashi S-I, Suetake I, Iwamatsu A, Endo TA, Shinga J, Mizutani-Koseki Y, Toyoda T, Okamura K, et al,. (2007) The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA. Nature 450, 908-912.
-
(2007)
Nature
, vol.450
, pp. 908-912
-
-
Sharif, J.1
Muto, M.2
Takebayashi, S.-I.3
Suetake, I.4
Iwamatsu, A.5
Endo, T.A.6
Shinga, J.7
Mizutani-Koseki, Y.8
Toyoda, T.9
Okamura, K.10
-
39
-
-
34648833002
-
UHRF1 plays a role in maintaining DNA methylation in mammalian cells
-
Bostick M, Kim JK, Esteve P-O, Clark A, Pradhan S, &, Jacobsen SE, (2007) UHRF1 plays a role in maintaining DNA methylation in mammalian cells. Science 317, 1760-1764.
-
(2007)
Science
, vol.317
, pp. 1760-1764
-
-
Bostick, M.1
Kim, J.K.2
Esteve, P.-O.3
Clark, A.4
Pradhan, S.5
Jacobsen, S.E.6
-
40
-
-
66149146320
-
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1
-
Tahiliani M, Koh KP, Shen Y, Pastor WA, Bandukwala H, Brudno Y, Agarwal S, Iyer LM, Liu DR, Aravind L, et al,. (2009) Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science 324, 930-935.
-
(2009)
Science
, vol.324
, pp. 930-935
-
-
Tahiliani, M.1
Koh, K.P.2
Shen, Y.3
Pastor, W.A.4
Bandukwala, H.5
Brudno, Y.6
Agarwal, S.7
Iyer, L.M.8
Liu, D.R.9
Aravind, L.10
-
41
-
-
32844459336
-
The polycomb group protein EZH2 directly controls DNA methylation
-
Viré E, Brenner C, Deplus R, Blanchon L, Fraga M, Didelot C, Morey L, Van Eynde A, Bernard D, Vanderwinden J-M, et al,. (2005) The polycomb group protein EZH2 directly controls DNA methylation. Nature 439, 871-874.
-
(2005)
Nature
, vol.439
, pp. 871-874
-
-
Viré, E.1
Brenner, C.2
Deplus, R.3
Blanchon, L.4
Fraga, M.5
Didelot, C.6
Morey, L.7
Van Eynde, A.8
Bernard, D.9
Vanderwinden, J.-M.10
-
42
-
-
0026708177
-
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
-
Li E, Bestor TH, &, Jaenisch R, (1992) Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 69, 915-926.
-
(1992)
Cell
, vol.69
, pp. 915-926
-
-
Li, E.1
Bestor, T.H.2
Jaenisch, R.3
-
43
-
-
84888015137
-
Super-enhancers in the control of cell identity and disease
-
Hnisz D, Abraham BJ, Lee TI, Lau A, Saint-André V, Sigova AA, Hoke HA, &, Young RA, (2013) Super-enhancers in the control of cell identity and disease. Cell 155, 934-947.
-
(2013)
Cell
, vol.155
, pp. 934-947
-
-
Hnisz, D.1
Abraham, B.J.2
Lee, T.I.3
Lau, A.4
Saint-André, V.5
Sigova, A.A.6
Hoke, H.A.7
Young, R.A.8
-
44
-
-
84876216563
-
Master transcription factors and mediator establish super-enhancers at key cell identity genes
-
Whyte WA, Orlando DA, Hnisz D, Abraham BJ, Lin CY, Kagey MH, Rahl PB, Lee TI, &, Young RA, (2013) Master transcription factors and mediator establish super-enhancers at key cell identity genes. Cell 153, 307-319.
-
(2013)
Cell
, vol.153
, pp. 307-319
-
-
Whyte, W.A.1
Orlando, D.A.2
Hnisz, D.3
Abraham, B.J.4
Lin, C.Y.5
Kagey, M.H.6
Rahl, P.B.7
Lee, T.I.8
Young, R.A.9
-
45
-
-
33847334699
-
Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome
-
Heintzman ND, Stuart RK, Hon G, Fu Y, Ching CW, Hawkins RD, Barrera LO, Van Calcar S, Qu C, Ching KA, et al,. (2007) Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome. Nat Genet 39, 311-318.
-
(2007)
Nat Genet
, vol.39
, pp. 311-318
-
-
Heintzman, N.D.1
Stuart, R.K.2
Hon, G.3
Fu, Y.4
Ching, C.W.5
Hawkins, R.D.6
Barrera, L.O.7
Van Calcar, S.8
Qu, C.9
Ching, K.A.10
-
46
-
-
84885021247
-
Epigenetic memory at embryonic enhancers identified in DNA methylation maps from adult mouse tissues
-
Hon GC, Rajagopal N, Shen Y, McCleary DF, Yue F, Dang MD, &, Ren B, (2013) Epigenetic memory at embryonic enhancers identified in DNA methylation maps from adult mouse tissues. Nat Genet 45, 1198-1206.
-
(2013)
Nat Genet
, vol.45
, pp. 1198-1206
-
-
Hon, G.C.1
Rajagopal, N.2
Shen, Y.3
McCleary, D.F.4
Yue, F.5
Dang, M.D.6
Ren, B.7
-
47
-
-
84903697261
-
Enhancer function: mechanistic and genome-wide insights come together
-
Plank JL, &, Dean A, (2014) Enhancer function: mechanistic and genome-wide insights come together. Mol Cell 55, 5-14.
-
(2014)
Mol Cell
, vol.55
, pp. 5-14
-
-
Plank, J.L.1
Dean, A.2
-
48
-
-
33644827383
-
Bone-marrow haematopoietic-stem-cell niches
-
Wilson A, &, Trumpp A, (2006) Bone-marrow haematopoietic-stem-cell niches. Nat Rev Immunol 6, 93-106.
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 93-106
-
-
Wilson, A.1
Trumpp, A.2
-
49
-
-
15944363056
-
Identification of Lin-Sca1 + kit+CD34 + Flt3 - short-term hematopoietic stem cells capable of rapidly reconstituting and rescuing myeloablated transplant recipients
-
Yang L, (2005) Identification of Lin-Sca1 + kit+CD34 + Flt3-short-term hematopoietic stem cells capable of rapidly reconstituting and rescuing myeloablated transplant recipients. Blood 105, 2717-2723.
-
(2005)
Blood
, vol.105
, pp. 2717-2723
-
-
Yang, L.1
-
50
-
-
84855469209
-
Polycomb group protein Bmi1 promotes hematopoietic cell development from embryonic stem cells
-
Ding X, Lin Q, Ensenat-Waser R, Rose-John S, &, Zenke M, (2012) Polycomb group protein Bmi1 promotes hematopoietic cell development from embryonic stem cells. Stem Cells Dev 21, 121-132.
-
(2012)
Stem Cells Dev
, vol.21
, pp. 121-132
-
-
Ding, X.1
Lin, Q.2
Ensenat-Waser, R.3
Rose-John, S.4
Zenke, M.5
-
51
-
-
33749350639
-
Differential impact of Ink4a and Arf on hematopoietic stem cells and their bone marrow microenvironment in Bmi1-deficient mice
-
Oguro H, Iwama A, Morita Y, Kamijo T, van Lohuizen M, &, Nakauchi H, (2006) Differential impact of Ink4a and Arf on hematopoietic stem cells and their bone marrow microenvironment in Bmi1-deficient mice. J Exp Med 203, 2247-2253.
-
(2006)
J Exp Med
, vol.203
, pp. 2247-2253
-
-
Oguro, H.1
Iwama, A.2
Morita, Y.3
Kamijo, T.4
Van Lohuizen, M.5
Nakauchi, H.6
-
52
-
-
77956282774
-
Opposing roles of polycomb repressive complexes in hematopoietic stem and progenitor cells
-
Majewski IJ, Ritchie ME, Phipson B, Corbin J, Pakusch M, Ebert A, Busslinger M, Koseki H, Hu Y, Smyth GK, et al,. (2010) Opposing roles of polycomb repressive complexes in hematopoietic stem and progenitor cells. Blood 116, 731-739.
-
(2010)
Blood
, vol.116
, pp. 731-739
-
-
Majewski, I.J.1
Ritchie, M.E.2
Phipson, B.3
Corbin, J.4
Pakusch, M.5
Ebert, A.6
Busslinger, M.7
Koseki, H.8
Hu, Y.9
Smyth, G.K.10
-
53
-
-
0037673984
-
Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells
-
Lessard J, &, Sauvageau G, (2003) Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells. Nature 423, 255-260.
-
(2003)
Nature
, vol.423
, pp. 255-260
-
-
Lessard, J.1
Sauvageau, G.2
-
54
-
-
77449159608
-
Poised lineage specification in multipotential hematopoietic stem and progenitor cells by the polycomb protein Bmi1
-
Oguro H, Yuan J, Ichikawa H, Ikawa T, Yamazaki S, Kawamoto H, Nakauchi H, &, Iwama A, (2010) Poised lineage specification in multipotential hematopoietic stem and progenitor cells by the polycomb protein Bmi1. Cell Stem Cell 6, 279-286.
-
(2010)
Cell Stem Cell
, vol.6
, pp. 279-286
-
-
Oguro, H.1
Yuan, J.2
Ichikawa, H.3
Ikawa, T.4
Yamazaki, S.5
Kawamoto, H.6
Nakauchi, H.7
Iwama, A.8
-
55
-
-
10344258563
-
Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1
-
Iwama A, Oguro H, Negishi M, Kato Y, Morita Y, Tsukui H, Ema H, Kamijo T, Katoh-Fukui Y, Koseki H, et al,. (2004) Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1. Immunity 21, 843-851.
-
(2004)
Immunity
, vol.21
, pp. 843-851
-
-
Iwama, A.1
Oguro, H.2
Negishi, M.3
Kato, Y.4
Morita, Y.5
Tsukui, H.6
Ema, H.7
Kamijo, T.8
Katoh-Fukui, Y.9
Koseki, H.10
-
56
-
-
33646070846
-
A bivalent chromatin structure marks key developmental genes in embryonic stem cells
-
Bernstein BE, Mikkelsen TS, Xie X, Kamal M, Huebert DJ, Cuff J, Fry B, Meissner A, Wernig M, Plath K, et al,. (2006) A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell 125, 315-326.
-
(2006)
Cell
, vol.125
, pp. 315-326
-
-
Bernstein, B.E.1
Mikkelsen, T.S.2
Xie, X.3
Kamal, M.4
Huebert, D.J.5
Cuff, J.6
Fry, B.7
Meissner, A.8
Wernig, M.9
Plath, K.10
-
57
-
-
84876485242
-
Polycomb Cbx family members mediate the balance between haematopoietic stem cell self-renewal and differentiation
-
Klauke K, Radulović V, Broekhuis M, Weersing E, Zwart E, Olthof S, Ritsema M, Bruggeman S, Wu X, Helin K, et al,. (2013) Polycomb Cbx family members mediate the balance between haematopoietic stem cell self-renewal and differentiation. Nat Cell Biol 15, 353-362.
-
(2013)
Nat Cell Biol
, vol.15
, pp. 353-362
-
-
Klauke, K.1
Radulović, V.2
Broekhuis, M.3
Weersing, E.4
Zwart, E.5
Olthof, S.6
Ritsema, M.7
Bruggeman, S.8
Wu, X.9
Helin, K.10
-
58
-
-
43249127096
-
Polycomb repressive complex 2 (PRC2) restricts hematopoietic stem cell activity
-
Majewski IJ, Blewitt ME, de Graaf CA, McManus EJ, Bahlo M, Hilton AA, Hyland CD, Smyth GK, Corbin JE, Metcalf D, et al,. (2008) Polycomb repressive complex 2 (PRC2) restricts hematopoietic stem cell activity. PLoS Biol 6, e93.
-
(2008)
PLoS Biol
, vol.6
, pp. e93
-
-
Majewski, I.J.1
Blewitt, M.E.2
De Graaf, C.A.3
McManus, E.J.4
Bahlo, M.5
Hilton, A.A.6
Hyland, C.D.7
Smyth, G.K.8
Corbin, J.E.9
Metcalf, D.10
-
59
-
-
84891740118
-
Polycomb repressive complex 2 regulates normal hematopoietic stem cell function in a developmental-stage-specific manner
-
Xie H, Xu J, Hsu JH, Nguyen M, Fujiwara Y, Peng C, &, Orkin SH, (2014) Polycomb repressive complex 2 regulates normal hematopoietic stem cell function in a developmental-stage-specific manner. Cell Stem Cell 14, 68-80.
-
(2014)
Cell Stem Cell
, vol.14
, pp. 68-80
-
-
Xie, H.1
Xu, J.2
Hsu, J.H.3
Nguyen, M.4
Fujiwara, Y.5
Peng, C.6
Orkin, S.H.7
-
60
-
-
84868340057
-
Ezh1 is required for hematopoietic stem cell maintenance and prevents senescence-like cell cycle arrest
-
Hidalgo I, Herrera-Merchan A, Ligos JM, Carramolino L, Nunez J, Martinez F, Dominguez O, Torres M, &, González S, (2012) Ezh1 is required for hematopoietic stem cell maintenance and prevents senescence-like cell cycle arrest. Cell Stem Cell 11, 649-662.
-
(2012)
Cell Stem Cell
, vol.11
, pp. 649-662
-
-
Hidalgo, I.1
Herrera-Merchan, A.2
Ligos, J.M.3
Carramolino, L.4
Nunez, J.5
Martinez, F.6
Dominguez, O.7
Torres, M.8
González, S.9
-
61
-
-
84893152923
-
The central role of EED in the orchestration of polycomb group complexes
-
Cao Q, Wang X, Zhao M, Yang R, Malik R, Qiao Y, Poliakov A, Yocum AK, Li Y, Chen W, et al,. (2014) The central role of EED in the orchestration of polycomb group complexes. Nat Commun 5, 1-13.
-
(2014)
Nat Commun
, vol.5
, pp. 1-13
-
-
Cao, Q.1
Wang, X.2
Zhao, M.3
Yang, R.4
Malik, R.5
Qiao, Y.6
Poliakov, A.7
Yocum, A.K.8
Li, Y.9
Chen, W.10
-
62
-
-
80052918929
-
Directional DNA methylation changes and complex intermediate states accompany lineage specificity in the adult hematopoietic compartment
-
Hodges E, Molaro A, Dos Santos CO, Thekkat P, Song Q, Uren PJ, Park J, Butler J, Rafii S, McCombie WR, et al,. (2011) Directional DNA methylation changes and complex intermediate states accompany lineage specificity in the adult hematopoietic compartment. Mol Cell 44, 17-28.
-
(2011)
Mol Cell
, vol.44
, pp. 17-28
-
-
Hodges, E.1
Molaro, A.2
Dos Santos, C.O.3
Thekkat, P.4
Song, Q.5
Uren, P.J.6
Park, J.7
Butler, J.8
Rafii, S.9
McCombie, W.R.10
-
63
-
-
70350654370
-
DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction
-
Bröske A-M, Vockentanz L, Kharazi S, Huska MR, Mancini E, Scheller M, Kuhl C, Enns A, Prinz M, Jaenisch R, et al,. (2009) DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction. Nat Genet 41, 1207-1215.
-
(2009)
Nat Genet
, vol.41
, pp. 1207-1215
-
-
Bröske, A.-M.1
Vockentanz, L.2
Kharazi, S.3
Huska, M.R.4
Mancini, E.5
Scheller, M.6
Kuhl, C.7
Enns, A.8
Prinz, M.9
Jaenisch, R.10
-
64
-
-
70349469788
-
DNA methyltransferase 1 is essential for and uniquely regulates hematopoietic stem and progenitor cells
-
Trowbridge JJ, Snow JW, Kim J, &, Orkin SH, (2009) DNA methyltransferase 1 is essential for and uniquely regulates hematopoietic stem and progenitor cells. Cell Stem Cell 5, 442-449.
-
(2009)
Cell Stem Cell
, vol.5
, pp. 442-449
-
-
Trowbridge, J.J.1
Snow, J.W.2
Kim, J.3
Orkin, S.H.4
-
65
-
-
34247337999
-
De novo DNA methyltransferase is essential for self-renewal, but not for differentiation, in hematopoietic stem cells
-
Tadokoro Y, Ema H, Okano M, Li E, &, Nakauchi H, (2007) De novo DNA methyltransferase is essential for self-renewal, but not for differentiation, in hematopoietic stem cells. J Exp Med 204, 715-722.
-
(2007)
J Exp Med
, vol.204
, pp. 715-722
-
-
Tadokoro, Y.1
Ema, H.2
Okano, M.3
Li, E.4
Nakauchi, H.5
-
66
-
-
84555207349
-
Dnmt3a is essential for hematopoietic stem cell differentiation
-
Challen GA, Sun D, Jeong M, Luo M, Jelinek J, Berg JS, Bock C, Vasanthakumar A, Gu H, Xi Y, et al,. (2012) Dnmt3a is essential for hematopoietic stem cell differentiation. Nat Genet 44, 23-31.
-
(2012)
Nat Genet
, vol.44
, pp. 23-31
-
-
Challen, G.A.1
Sun, D.2
Jeong, M.3
Luo, M.4
Jelinek, J.5
Berg, J.S.6
Bock, C.7
Vasanthakumar, A.8
Gu, H.9
Xi, Y.10
-
67
-
-
84891372425
-
Large conserved domains of low DNA methylation maintained by Dnmt3a
-
Jeong M, Sun D, Luo M, Huang Y, Challen GA, Rodriguez B, Zhang X, Chavez L, Wang H, Hannah R, et al,. (2014) Large conserved domains of low DNA methylation maintained by Dnmt3a. Nat Genet 46, 17-23.
-
(2014)
Nat Genet
, vol.46
, pp. 17-23
-
-
Jeong, M.1
Sun, D.2
Luo, M.3
Huang, Y.4
Challen, G.A.5
Rodriguez, B.6
Zhang, X.7
Chavez, L.8
Wang, H.9
Hannah, R.10
-
68
-
-
84899768899
-
Epigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal
-
Sun D, Luo M, Jeong M, Rodriguez B, Xia Z, Hannah R, Wang H, Le T, Faull KF, Chen R, et al,. (2014) Epigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal. Cell Stem Cell 14, 673-688.
-
(2014)
Cell Stem Cell
, vol.14
, pp. 673-688
-
-
Sun, D.1
Luo, M.2
Jeong, M.3
Rodriguez, B.4
Xia, Z.5
Hannah, R.6
Wang, H.7
Le, T.8
Faull, K.F.9
Chen, R.10
-
69
-
-
84869162797
-
G9a/GLP-dependent histone H3K9me2 patterning during human hematopoietic stem cell lineage commitment
-
Chen X, Skutt-Kakaria K, Davison J, Ou YL, Choi E, Malik P, Loeb K, Wood B, Georges G, Torok-Storb B, et al,. (2012) G9a/GLP-dependent histone H3K9me2 patterning during human hematopoietic stem cell lineage commitment. Genes Dev 26, 2499-2511.
-
(2012)
Genes Dev
, vol.26
, pp. 2499-2511
-
-
Chen, X.1
Skutt-Kakaria, K.2
Davison, J.3
Ou, Y.L.4
Choi, E.5
Malik, P.6
Loeb, K.7
Wood, B.8
Georges, G.9
Torok-Storb, B.10
-
70
-
-
84893972052
-
The methyltransferase G9a regulates HoxA9-dependent transcription in AML
-
Lehnertz B, Pabst C, Su L, Miller M, Liu F, Yi L, Zhang R, Krosl J, Yung E, Kirschner J, et al,. (2014) The methyltransferase G9a regulates HoxA9-dependent transcription in AML. Genes Dev 28, 317-327.
-
(2014)
Genes Dev
, vol.28
, pp. 317-327
-
-
Lehnertz, B.1
Pabst, C.2
Su, L.3
Miller, M.4
Liu, F.5
Yi, L.6
Zhang, R.7
Krosl, J.8
Yung, E.9
Kirschner, J.10
-
71
-
-
84861870951
-
The COMPASS family of histone H3K4 methylases: mechanisms of regulation in development and disease pathogenesis
-
Shilatifard A, (2012) The COMPASS family of histone H3K4 methylases: mechanisms of regulation in development and disease pathogenesis. Annu Rev Biochem 81, 65-95.
-
(2012)
Annu Rev Biochem
, vol.81
, pp. 65-95
-
-
Shilatifard, A.1
-
72
-
-
84901281295
-
The histone methyltransferase activityof MLL1 is dispensable for hematopoiesis and leukemogenesis
-
Mishra BP, Zaffuto KM, Artinger EL, Org T, Mikkola HKA, Cheng C, Djabali M, &, Ernst P, (2014) The histone methyltransferase activityof MLL1 is dispensable for hematopoiesis and leukemogenesis. Cell Rep 7, 1239-1247.
-
(2014)
Cell Rep
, vol.7
, pp. 1239-1247
-
-
Mishra, B.P.1
Zaffuto, K.M.2
Artinger, E.L.3
Org, T.4
Mikkola, H.K.A.5
Cheng, C.6
Djabali, M.7
Ernst, P.8
-
73
-
-
60749125436
-
Epidermal homeostasis: a balancing act of stem cells in the skin
-
Blanpain C, &, Fuchs E, (2009) Epidermal homeostasis: a balancing act of stem cells in the skin. Nat Rev Mol Cell Biol 10, 207-217.
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 207-217
-
-
Blanpain, C.1
Fuchs, E.2
-
74
-
-
84868457573
-
Chromatin regulators in mammalian epidermis
-
Frye M, &, Benitah SA, (2012) Chromatin regulators in mammalian epidermis. Semin Cell Dev Biol 23, 897-905.
-
(2012)
Semin Cell Dev Biol
, vol.23
, pp. 897-905
-
-
Frye, M.1
Benitah, S.A.2
-
75
-
-
0027195638
-
Separation of human epidermal stem cells from transit amplifying cells on the basis of differences in integrin function and expression
-
Jones PH, &, Watt FM, (1993) Separation of human epidermal stem cells from transit amplifying cells on the basis of differences in integrin function and expression. Cell 73, 713-724.
-
(1993)
Cell
, vol.73
, pp. 713-724
-
-
Jones, P.H.1
Watt, F.M.2
-
76
-
-
80052261506
-
Jarid2 regulates mouse epidermal stem cell activation and differentiation
-
Mejetta S, Morey L, Pascual G, Kuebler B, Mysliwiec MR, Lee Y, Shiekhattar R, Di Croce L, &, Benitah SA, (2011) Jarid2 regulates mouse epidermal stem cell activation and differentiation. EMBO J 30, 3635-3646.
-
(2011)
EMBO J
, vol.30
, pp. 3635-3646
-
-
Mejetta, S.1
Morey, L.2
Pascual, G.3
Kuebler, B.4
Mysliwiec, M.R.5
Lee, Y.6
Shiekhattar, R.7
Di Croce, L.8
Benitah, S.A.9
-
77
-
-
47549105128
-
Control of differentiation in a self-renewing mammalian tissue by the histone demethylase JMJD3
-
Sen GL, Webster DE, Barragan DI, Chang HY, &, Khavari PA, (2008) Control of differentiation in a self-renewing mammalian tissue by the histone demethylase JMJD3. Genes Dev 22, 1865-1870.
-
(2008)
Genes Dev
, vol.22
, pp. 1865-1870
-
-
Sen, G.L.1
Webster, D.E.2
Barragan, D.I.3
Chang, H.Y.4
Khavari, P.A.5
-
78
-
-
62149122634
-
Ezh2 orchestrates gene expression for the stepwise differentiation of tissue-specific stem cells
-
Ezhkova E, Pasolli HA, Parker JS, Stokes N, Su I-H, Hannon G, Tarakhovsky A, &, Fuchs E, (2009) Ezh2 orchestrates gene expression for the stepwise differentiation of tissue-specific stem cells. Cell 136, 1122-1135.
-
(2009)
Cell
, vol.136
, pp. 1122-1135
-
-
Ezhkova, E.1
Pasolli, H.A.2
Parker, J.S.3
Stokes, N.4
Su, I.-H.5
Hannon, G.6
Tarakhovsky, A.7
Fuchs, E.8
-
79
-
-
79952220410
-
EZH1 and EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair
-
Ezhkova E, Lien WH, Stokes N, Pasolli HA, Silva JM, &, Fuchs E, (2011) EZH1 and EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair. Genes Dev 25, 485-498.
-
(2011)
Genes Dev
, vol.25
, pp. 485-498
-
-
Ezhkova, E.1
Lien, W.H.2
Stokes, N.3
Pasolli, H.A.4
Silva, J.M.5
Fuchs, E.6
-
80
-
-
80052300618
-
Regulation of human epidermal stem cell proliferation and senescence requires polycomb-dependent and -independent functions of Cbx4
-
Luis NM, Morey L, Mejetta S, Pascual G, Janich P, Kuebler B, Cozutto L, Roma G, Nascimento E, Frye M, et al,. (2011) Regulation of human epidermal stem cell proliferation and senescence requires polycomb-dependent and -independent functions of Cbx4. Cell Stem Cell 9, 233-246.
-
(2011)
Cell Stem Cell
, vol.9
, pp. 233-246
-
-
Luis, N.M.1
Morey, L.2
Mejetta, S.3
Pascual, G.4
Janich, P.5
Kuebler, B.6
Cozutto, L.7
Roma, G.8
Nascimento, E.9
Frye, M.10
-
81
-
-
37049014475
-
Expression of Bmi-1 in epidermis enhances cell survival by altering cell cycle regulatory protein expression and inhibiting apoptosis
-
Lee K, Adhikary G, Balasubramanian S, Gopalakrishnan R, McCormick T, Dimri GP, Eckert RL, &, Rorke EA, (2007) Expression of Bmi-1 in epidermis enhances cell survival by altering cell cycle regulatory protein expression and inhibiting apoptosis. J Invest Dermatol 128, 9-17.
-
(2007)
J Invest Dermatol
, vol.128
, pp. 9-17
-
-
Lee, K.1
Adhikary, G.2
Balasubramanian, S.3
Gopalakrishnan, R.4
McCormick, T.5
Dimri, G.P.6
Eckert, R.L.7
Rorke, E.A.8
-
82
-
-
79956033054
-
p63, a story of mice and men
-
Vanbokhoven H, Melino G, Candi E, &, Declercq W, (2011) p63, a story of mice and men. J Invest Dermatol 131, 1196-1207.
-
(2011)
J Invest Dermatol
, vol.131
, pp. 1196-1207
-
-
Vanbokhoven, H.1
Melino, G.2
Candi, E.3
Declercq, W.4
-
83
-
-
84856449868
-
The histone methyltransferase Setd8 acts in concert with c-Myc and is required to maintain skin
-
Driskell I, Oda H, Blanco S, Nascimento E, Humphreys P, &, Frye M, (2012) The histone methyltransferase Setd8 acts in concert with c-Myc and is required to maintain skin. EMBO J 31, 616-629.
-
(2012)
EMBO J
, vol.31
, pp. 616-629
-
-
Driskell, I.1
Oda, H.2
Blanco, S.3
Nascimento, E.4
Humphreys, P.5
Frye, M.6
-
84
-
-
78649907734
-
Hdac1 and Hdac2 act redundantly to control p63 and p53 functions in epidermal progenitor cells
-
LeBoeuf M, Terrell A, Trivedi S, Sinha S, Epstein JA, Olson EN, Morrisey EE, &, Millar SE, (2010) Hdac1 and Hdac2 act redundantly to control p63 and p53 functions in epidermal progenitor cells. Dev Cell 19, 807-818.
-
(2010)
Dev Cell
, vol.19
, pp. 807-818
-
-
LeBoeuf, M.1
Terrell, A.2
Trivedi, S.3
Sinha, S.4
Epstein, J.A.5
Olson, E.N.6
Morrisey, E.E.7
Millar, S.E.8
-
85
-
-
79551607574
-
DeltaNp63alpha is an oncogene that targets chromatin remodeler Lsh to drive skin stem cell proliferation and tumorigenesis
-
Keyes WM, Pecoraro M, Aranda V, Vernersson-Lindahl E, Li W, Vogel H, Guo X, Garcia EL, Michurina TV, Enikolopov G, et al,. (2011) DeltaNp63alpha is an oncogene that targets chromatin remodeler Lsh to drive skin stem cell proliferation and tumorigenesis. Cell Stem Cell 8, 164-176.
-
(2011)
Cell Stem Cell
, vol.8
, pp. 164-176
-
-
Keyes, W.M.1
Pecoraro, M.2
Aranda, V.3
Vernersson-Lindahl, E.4
Li, W.5
Vogel, H.6
Guo, X.7
Garcia, E.L.8
Michurina, T.V.9
Enikolopov, G.10
-
86
-
-
84890535371
-
p63 and Brg1 control developmentally regulated higher-order chromatin remodelling at the epidermal differentiation complex locus in epidermal progenitor cells
-
Mardaryev AN, Gdula MR, Yarker JL, Emelianov VN, Poterlowicz K, Sharov AA, Sharova TY, Scarpa JA, Chambon P, Botchkarev VA, et al,. (2014) p63 and Brg1 control developmentally regulated higher-order chromatin remodelling at the epidermal differentiation complex locus in epidermal progenitor cells. Development 141, 101-111.
-
(2014)
Development
, vol.141
, pp. 101-111
-
-
Mardaryev, A.N.1
Gdula, M.R.2
Yarker, J.L.3
Emelianov, V.N.4
Poterlowicz, K.5
Sharov, A.A.6
Sharova, T.Y.7
Scarpa, J.A.8
Chambon, P.9
Botchkarev, V.A.10
-
87
-
-
80053956232
-
p63 regulates Satb1 to control tissue-specific chromatin remodeling during development of the epidermis
-
Fessing MY, Mardaryev AN, Gdula MR, Sharov AA, Sharova TY, Rapisarda V, Gordon KB, Smorodchenko AD, Poterlowicz K, Ferone G, et al,. (2011) p63 regulates Satb1 to control tissue-specific chromatin remodeling during development of the epidermis. J Cell Biol 194, 825-839.
-
(2011)
J Cell Biol
, vol.194
, pp. 825-839
-
-
Fessing, M.Y.1
Mardaryev, A.N.2
Gdula, M.R.3
Sharov, A.A.4
Sharova, T.Y.5
Rapisarda, V.6
Gordon, K.B.7
Smorodchenko, A.D.8
Poterlowicz, K.9
Ferone, G.10
-
88
-
-
39749124274
-
MYC in mammalian epidermis: how can an oncogene stimulate differentiation?
-
Watt FM, Frye M, &, Benitah SA, (2008) MYC in mammalian epidermis: how can an oncogene stimulate differentiation? Nat Rev Cancer 8, 234-242.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 234-242
-
-
Watt, F.M.1
Frye, M.2
Benitah, S.A.3
-
89
-
-
70350233471
-
Acting locally and globally: Myc's ever-expanding roles on chromatin
-
Varlakhanova NV, &, Knoepfler PS, (2009) Acting locally and globally: Myc's ever-expanding roles on chromatin. Cancer Res 69, 7487-7490.
-
(2009)
Cancer Res
, vol.69
, pp. 7487-7490
-
-
Varlakhanova, N.V.1
Knoepfler, P.S.2
-
90
-
-
0035901594
-
c-Myc activation in transgenic mouse epidermis results in mobilization of stem cells and differentiation of their progeny
-
Arnold I, &, Watt FM, (2001) c-Myc activation in transgenic mouse epidermis results in mobilization of stem cells and differentiation of their progeny. Curr Biol 11, 558-568.
-
(2001)
Curr Biol
, vol.11
, pp. 558-568
-
-
Arnold, I.1
Watt, F.M.2
-
91
-
-
0042913170
-
Evidence that Myc activation depletes the epidermal stem cell compartment by modulating adhesive interactions with the local microenvironment
-
Frye M, Gardner C, Li ER, Arnold I, &, Watt FM, (2003) Evidence that Myc activation depletes the epidermal stem cell compartment by modulating adhesive interactions with the local microenvironment. Development 130, 2793-2808.
-
(2003)
Development
, vol.130
, pp. 2793-2808
-
-
Frye, M.1
Gardner, C.2
Li, E.R.3
Arnold, I.4
Watt, F.M.5
-
92
-
-
84856161647
-
The opposing transcriptional functions of Sin3a and c-Myc are required to maintain tissue homeostasis
-
Nascimento EM, Cox CL, MacArthur S, Hussain S, Trotter M, Blanco S, Suraj M, Nichols J, Kubler B, Benitah SA, et al,. (2011) The opposing transcriptional functions of Sin3a and c-Myc are required to maintain tissue homeostasis. Nat Cell Biol 13, 1395-1405.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 1395-1405
-
-
Nascimento, E.M.1
Cox, C.L.2
MacArthur, S.3
Hussain, S.4
Trotter, M.5
Blanco, S.6
Suraj, M.7
Nichols, J.8
Kubler, B.9
Benitah, S.A.10
-
93
-
-
9244234957
-
Mouse Sin3A interacts with and can functionally substitute for the amino-terminal repression of the Myc antagonist Mxi1
-
Rao G, Alland L, Guida P, Schreiber-Agus N, Chen K, Chin L, Rochelle JM, Seldin MF, Skoultchi AI, &, DePinho RA, (1996) Mouse Sin3A interacts with and can functionally substitute for the amino-terminal repression of the Myc antagonist Mxi1. Oncogene 12, 1165-1172.
-
(1996)
Oncogene
, vol.12
, pp. 1165-1172
-
-
Rao, G.1
Alland, L.2
Guida, P.3
Schreiber-Agus, N.4
Chen, K.5
Chin, L.6
Rochelle, J.M.7
Seldin, M.F.8
Skoultchi, A.I.9
DePinho, R.A.10
-
94
-
-
0030969516
-
Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression
-
Laherty CD, Yang WM, Sun JM, Davie JR, Seto E, &, Eisenman RN, (1997) Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression. Cell 89, 349-356.
-
(1997)
Cell
, vol.89
, pp. 349-356
-
-
Laherty, C.D.1
Yang, W.M.2
Sun, J.M.3
Davie, J.R.4
Seto, E.5
Eisenman, R.N.6
-
95
-
-
0031007189
-
Histone deacetylase activity is required for full transcriptional repression by mSin3A
-
Hassig CA, Fleischer TC, Billin AN, Schreiber SL, &, Ayer DE, (1997) Histone deacetylase activity is required for full transcriptional repression by mSin3A. Cell 89, 341-347.
-
(1997)
Cell
, vol.89
, pp. 341-347
-
-
Hassig, C.A.1
Fleischer, T.C.2
Billin, A.N.3
Schreiber, S.L.4
Ayer, D.E.5
-
96
-
-
75749104729
-
DNMT1 maintains progenitor function in self-renewing somatic tissue
-
Sen GL, Reuter JA, Webster DE, Zhu L, &, Khavari PA, (2010) DNMT1 maintains progenitor function in self-renewing somatic tissue. Nature 463, 563-567.
-
(2010)
Nature
, vol.463
, pp. 563-567
-
-
Sen, G.L.1
Reuter, J.A.2
Webster, D.E.3
Zhu, L.4
Khavari, P.A.5
-
97
-
-
84870488608
-
Progressive alopecia reveals decreasing stem cell activation probability during aging of mice with epidermal deletion of DNA methyltransferase 1
-
Li J, Jiang T-X, Hughes MW, Wu P, Widelitz RB, Fan G, &, Chuong C-M, (2012) Progressive alopecia reveals decreasing stem cell activation probability during aging of mice with epidermal deletion of DNA methyltransferase 1. J Invest Dermatol 132, 2681-2690.
-
(2012)
J Invest Dermatol
, vol.132
, pp. 2681-2690
-
-
Li, J.1
Jiang, T.-X.2
Hughes, M.W.3
Wu, P.4
Widelitz, R.B.5
Fan, G.6
Chuong, C.-M.7
-
98
-
-
71149121303
-
Control of cognition and adaptive behavior by the GLP/G9a epigenetic suppressor complex
-
Schaefer A, Sampath SC, Intrator A, Min A, Gertler TS, Surmeier DJ, Tarakhovsky A, &, Greengard P, (2009) Control of cognition and adaptive behavior by the GLP/G9a epigenetic suppressor complex. Neuron 64, 678-691.
-
(2009)
Neuron
, vol.64
, pp. 678-691
-
-
Schaefer, A.1
Sampath, S.C.2
Intrator, A.3
Min, A.4
Gertler, T.S.5
Surmeier, D.J.6
Tarakhovsky, A.7
Greengard, P.8
-
99
-
-
84897392611
-
G9a influences neuronal subtype specification in striatum
-
Maze I, Chaudhury D, Dietz DM, Von Schimmelmann M, Kennedy PJ, Lobo MK, Sillivan SE, Miller ML, Bagot RC, Sun H, et al,. (2014) G9a influences neuronal subtype specification in striatum. Nat Neurosci 17, 533-539.
-
(2014)
Nat Neurosci
, vol.17
, pp. 533-539
-
-
Maze, I.1
Chaudhury, D.2
Dietz, D.M.3
Von Schimmelmann, M.4
Kennedy, P.J.5
Lobo, M.K.6
Sillivan, S.E.7
Miller, M.L.8
Bagot, R.C.9
Sun, H.10
-
100
-
-
22344449361
-
Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways
-
Molofsky AV, He S, Bydon M, Morrison SJ, &, Pardal R, (2005) Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways. Genes Dev 19, 1432-1437.
-
(2005)
Genes Dev
, vol.19
, pp. 1432-1437
-
-
Molofsky, A.V.1
He, S.2
Bydon, M.3
Morrison, S.J.4
Pardal, R.5
-
101
-
-
0242667922
-
Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation
-
Molofsky AV, Pardal R, Iwashita T, Park I-K, Clarke MF, &, Morrison SJ, (2003) Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation. Nature 425, 962-967.
-
(2003)
Nature
, vol.425
, pp. 962-967
-
-
Molofsky, A.V.1
Pardal, R.2
Iwashita, T.3
Park, I.-K.4
Clarke, M.F.5
Morrison, S.J.6
-
102
-
-
77957680712
-
Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex
-
Pereira JD, Sansom SN, Smith J, Dobenecker M-W, Tarakhovsky A, &, Livesey FJ, (2010) Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex. Proc Natl Acad Sci USA 107, 15957-15962.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 15957-15962
-
-
Pereira, J.D.1
Sansom, S.N.2
Smith, J.3
Dobenecker, M.-W.4
Tarakhovsky, A.5
Livesey, F.J.6
-
103
-
-
79953211498
-
EZH2 Regulates neuronal differentiation of mesenchymal stem cells through PIP5K1C-dependent calcium signaling
-
Yu YL, Chou RH, Chen LT, Shyu WC, Hsieh SC, Wu CS, Zeng HJ, Yeh SP, Yang DM, Hung SC, et al,. (2011) EZH2 Regulates neuronal differentiation of mesenchymal stem cells through PIP5K1C-dependent calcium signaling. J Biol Chem 286, 9657-9667.
-
(2011)
J Biol Chem
, vol.286
, pp. 9657-9667
-
-
Yu, Y.L.1
Chou, R.H.2
Chen, L.T.3
Shyu, W.C.4
Hsieh, S.C.5
Wu, C.S.6
Zeng, H.J.7
Yeh, S.P.8
Yang, D.M.9
Hung, S.C.10
-
104
-
-
33749241112
-
Transition of mouse de novo methyltransferases expression from Dnmt3b to Dnmt3a during neural progenitor cell development
-
Watanabe D, Uchiyama K, &, Hanaoka K, (2006) Transition of mouse de novo methyltransferases expression from Dnmt3b to Dnmt3a during neural progenitor cell development. Neuroscience 142, 727-737.
-
(2006)
Neuroscience
, vol.142
, pp. 727-737
-
-
Watanabe, D.1
Uchiyama, K.2
Hanaoka, K.3
-
105
-
-
24344472335
-
DNA methylation controls the timing of astrogliogenesis through regulation of JAK-STAT signaling
-
Fan G, Martinowich K, Chin MH, He F, Fouse SD, Hutnick L, Hattori D, Ge W, Shen Y, Wu H, et al,. (2005) DNA methylation controls the timing of astrogliogenesis through regulation of JAK-STAT signaling. Development 132, 3345-3356.
-
(2005)
Development
, vol.132
, pp. 3345-3356
-
-
Fan, G.1
Martinowich, K.2
Chin, M.H.3
He, F.4
Fouse, S.D.5
Hutnick, L.6
Hattori, D.7
Ge, W.8
Shen, Y.9
Wu, H.10
-
106
-
-
77954842322
-
Dnmt3a-dependent nonpromoter DNA methylation facilitates transcription of neurogenic genes
-
Wu H, Coskun V, Tao J, Xie W, Ge W, Yoshikawa K, Li E, Zhang Y, &, Sun YE, (2010) Dnmt3a-dependent nonpromoter DNA methylation facilitates transcription of neurogenic genes. Science 329, 444-448.
-
(2010)
Science
, vol.329
, pp. 444-448
-
-
Wu, H.1
Coskun, V.2
Tao, J.3
Xie, W.4
Ge, W.5
Yoshikawa, K.6
Li, E.7
Zhang, Y.8
Sun, Y.E.9
-
107
-
-
77950187447
-
Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons
-
Feng J, Zhou Y, Campbell SL, Le T, Li E, Sweatt JD, Silva AJ, &, Fan G, (2010) Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons. Nat Neurosci 13, 423-430.
-
(2010)
Nat Neurosci
, vol.13
, pp. 423-430
-
-
Feng, J.1
Zhou, Y.2
Campbell, S.L.3
Le, T.4
Li, E.5
Sweatt, J.D.6
Silva, A.J.7
Fan, G.8
-
108
-
-
79958071640
-
ICF syndrome mutations cause a broad spectrum of biochemical defects in DNMT3B-mediated de novo DNA methylation
-
Moarefi AH, &, Chédin F, (2011) ICF syndrome mutations cause a broad spectrum of biochemical defects in DNMT3B-mediated de novo DNA methylation. J Mol Biol 409, 758-772.
-
(2011)
J Mol Biol
, vol.409
, pp. 758-772
-
-
Moarefi, A.H.1
Chédin, F.2
-
109
-
-
39749152283
-
DNA methyltransferase 3B (DNMT3B) mutations in ICF syndrome lead to altered epigenetic modifications and aberrant expression of genes regulating development, neurogenesis and immune function
-
Jin B, Tao Q, Peng J, Soo HM, Wu W, Ying J, Fields CR, Delmas AL, Liu X, Qiu J, et al,. (2007) DNA methyltransferase 3B (DNMT3B) mutations in ICF syndrome lead to altered epigenetic modifications and aberrant expression of genes regulating development, neurogenesis and immune function. Hum Mol Genet 17, 690-709.
-
(2007)
Hum Mol Genet
, vol.17
, pp. 690-709
-
-
Jin, B.1
Tao, Q.2
Peng, J.3
Soo, H.M.4
Wu, W.5
Ying, J.6
Fields, C.R.7
Delmas, A.L.8
Liu, X.9
Qiu, J.10
-
110
-
-
84885945266
-
Heterogeneous clinical presentation in ICF syndrome: correlation with underlying gene defects
-
Weemaes CM, van Tol MJ, Wang J, van Ostaijen-ten Dam MM, van Eggermond MC, Thijssen PE, Aytekin C, Brunetti-Pierri N, van der Burg M, Davies EG, et al,. (2013) Heterogeneous clinical presentation in ICF syndrome: correlation with underlying gene defects. Eur J Hum Genet 21, 1219-1225.
-
(2013)
Eur J Hum Genet
, vol.21
, pp. 1219-1225
-
-
Weemaes, C.M.1
Van Tol, M.J.2
Wang, J.3
Van Ostaijen-Ten Dam, M.M.4
Van Eggermond, M.C.5
Thijssen, P.E.6
Aytekin, C.7
Brunetti-Pierri, N.8
Van Der Burg, M.9
Davies, E.G.10
-
111
-
-
79960127277
-
Tissue-specific distribution and dynamic changes of 5-hydroxymethylcytosine in mammalian genomes
-
Kinney SM, Chin HG, Vaisvila R, Bitinaite J, Zheng Y, Esteve PO, Feng S, Stroud H, Jacobsen SE, &, Pradhan S, (2011) Tissue-specific distribution and dynamic changes of 5-hydroxymethylcytosine in mammalian genomes. J Biol Chem 286, 24685-24693.
-
(2011)
J Biol Chem
, vol.286
, pp. 24685-24693
-
-
Kinney, S.M.1
Chin, H.G.2
Vaisvila, R.3
Bitinaite, J.4
Zheng, Y.5
Esteve, P.O.6
Feng, S.7
Stroud, H.8
Jacobsen, S.E.9
Pradhan, S.10
-
112
-
-
84892449532
-
Dynamic changes in DNA methylation and hydroxymethylation when hES cells undergo differentiation toward a neuronal lineage
-
Kim M, Park YK, Kang TW, Lee SH, Rhee YH, Park JL, Kim HJ, Lee D, Lee D, Kim SY, et al,. (2014) Dynamic changes in DNA methylation and hydroxymethylation when hES cells undergo differentiation toward a neuronal lineage. Hum Mol Genet 23, 657-667.
-
(2014)
Hum Mol Genet
, vol.23
, pp. 657-667
-
-
Kim, M.1
Park, Y.K.2
Kang, T.W.3
Lee, S.H.4
Rhee, Y.H.5
Park, J.L.6
Kim, H.J.7
Lee, D.8
Lee, D.9
Kim, S.Y.10
-
113
-
-
66149123748
-
The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain
-
Kriaucionis S, &, Heintz N, (2009) The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain. Science 324, 929-930.
-
(2009)
Science
, vol.324
, pp. 929-930
-
-
Kriaucionis, S.1
Heintz, N.2
-
114
-
-
84874252793
-
Dynamics of 5-hydroxymethylcytosine and chromatin marks in mammalian neurogenesis
-
Hahn MA, Qiu R, Wu X, Li AX, Zhang H, Wang J, Jui J, Jin S-G, Jiang Y, Pfeifer GP, et al,. (2013) Dynamics of 5-hydroxymethylcytosine and chromatin marks in mammalian neurogenesis. Cell Rep 3, 291-300.
-
(2013)
Cell Rep
, vol.3
, pp. 291-300
-
-
Hahn, M.A.1
Qiu, R.2
Wu, X.3
Li, A.X.4
Zhang, H.5
Wang, J.6
Jui, J.7
Jin, S.-G.8
Jiang, Y.9
Pfeifer, G.P.10
-
115
-
-
84881178902
-
Tet1 regulates adult hippocampal neurogenesis and cognition
-
Zhang R-R, Cui Q-Y, Murai K, Lim YC, Smith ZD, Jin S, Ye P, Rosa L, Lee YK, Wu H-P, et al,. (2013) Tet1 regulates adult hippocampal neurogenesis and cognition. Cell Stem Cell 13, 237-245.
-
(2013)
Cell Stem Cell
, vol.13
, pp. 237-245
-
-
Zhang, R.-R.1
Cui, Q.-Y.2
Murai, K.3
Lim, Y.C.4
Smith, Z.D.5
Jin, S.6
Ye, P.7
Rosa, L.8
Lee, Y.K.9
Wu, H.-P.10
-
116
-
-
0000642664
-
Satellite cell of skeletal muscle fibers
-
Mauro A, (1961) Satellite cell of skeletal muscle fibers. J Biophys Biochem Cytol 9, 493-495.
-
(1961)
J Biophys Biochem Cytol
, vol.9
, pp. 493-495
-
-
Mauro, A.1
-
117
-
-
34247236574
-
Stem and progenitor cells in skeletal muscle development, maintenance, and therapy
-
Péault B, Rudnicki M, Torrente Y, Cossu G, Tremblay JP, Partridge T, Gussoni E, Kunkel LM, &, Huard J, (2007) Stem and progenitor cells in skeletal muscle development, maintenance, and therapy. Mol Ther 15, 867-877.
-
(2007)
Mol Ther
, vol.15
, pp. 867-877
-
-
Péault, B.1
Rudnicki, M.2
Torrente, Y.3
Cossu, G.4
Tremblay, J.P.5
Partridge, T.6
Gussoni, E.7
Kunkel, L.M.8
Huard, J.9
-
118
-
-
84860627842
-
Tissue-specific stem cells: lessons from the skeletal muscle satellite cell
-
Brack AS, &, Rando TA, (2012) Tissue-specific stem cells: lessons from the skeletal muscle satellite cell. Cell Stem Cell 10, 504-514.
-
(2012)
Cell Stem Cell
, vol.10
, pp. 504-514
-
-
Brack, A.S.1
Rando, T.A.2
-
119
-
-
7544230144
-
The polycomb Ezh2 methyltransferase regulates muscle gene expression and skeletal muscle differentiation
-
Caretti G, Di Padova M, Micales B, Lyons GE, &, Sartorelli V, (2004) The polycomb Ezh2 methyltransferase regulates muscle gene expression and skeletal muscle differentiation. Genes Dev 18, 2627-2638.
-
(2004)
Genes Dev
, vol.18
, pp. 2627-2638
-
-
Caretti, G.1
Di Padova, M.2
Micales, B.3
Lyons, G.E.4
Sartorelli, V.5
-
120
-
-
80052571043
-
Chromatin regulated interchange between polycomb repressive complex 2 (PRC2)-Ezh2 and PRC2-Ezh1 complexes controls myogenin activation in skeletal muscle cells
-
Stojic L, Jasencakova Z, Prezioso C, Stützer A, Bodega B, Pasini D, Klingberg R, Mozzetta C, Margueron R, Puri PL, et al,. (2011) Chromatin regulated interchange between polycomb repressive complex 2 (PRC2)-Ezh2 and PRC2-Ezh1 complexes controls myogenin activation in skeletal muscle cells. Epigenetics Chromatin 4, 16.
-
(2011)
Epigenetics Chromatin
, vol.4
, pp. 16
-
-
Stojic, L.1
Jasencakova, Z.2
Prezioso, C.3
Stützer, A.4
Bodega, B.5
Pasini, D.6
Klingberg, R.7
Mozzetta, C.8
Margueron, R.9
Puri, P.L.10
-
121
-
-
79959349283
-
Genome-wide remodeling of the epigenetic landscape during myogenic differentiation
-
Asp P, Blum R, Vethantham V, Parisi F, Micsinai M, Cheng J, Bowman C, Kluger Y, &, Dynlacht BD, (2011) Genome-wide remodeling of the epigenetic landscape during myogenic differentiation. Proc Natl Acad Sci USA 108, E149-E158.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. E149-E158
-
-
Asp, P.1
Blum, R.2
Vethantham, V.3
Parisi, F.4
Micsinai, M.5
Cheng, J.6
Bowman, C.7
Kluger, Y.8
Dynlacht, B.D.9
-
122
-
-
80655132038
-
Bmi1 is expressed in postnatal myogenic satellite cells, controls their maintenance and plays an essential role in repeated muscle regeneration
-
Robson LG, Di Foggia V, Radunovic A, Bird K, Zhang X, &, Marino S, (2011) Bmi1 is expressed in postnatal myogenic satellite cells, controls their maintenance and plays an essential role in repeated muscle regeneration. PLoS One 6, e27116.
-
(2011)
PLoS One
, vol.6
-
-
Robson, L.G.1
Di Foggia, V.2
Radunovic, A.3
Bird, K.4
Zhang, X.5
Marino, S.6
-
123
-
-
84894232184
-
Geriatric muscle stem cells switch reversible quiescence into senescence
-
Sousa-Victor P, Gutarra S, García-Prat L, Rodriguez-Ubreva J, Ortet L, Ruiz-Bonilla V, Jardí M, Ballestar E, González S, Serrano AL, et al,. (2014) Geriatric muscle stem cells switch reversible quiescence into senescence. Nature 506, 316-321.
-
(2014)
Nature
, vol.506
, pp. 316-321
-
-
Sousa-Victor, P.1
Gutarra, S.2
García-Prat, L.3
Rodriguez-Ubreva, J.4
Ortet, L.5
Ruiz-Bonilla, V.6
Jardí, M.7
Ballestar, E.8
González, S.9
Serrano, A.L.10
-
124
-
-
84875734577
-
Early de novo DNA methylation and prolonged demethylation in the muscle lineage
-
Tsumagari K, Baribault C, Terragni J, Varley KE, Gertz J, Pradhan S, Badoo M, Crain CM, Song L, Crawford GE, et al,. (2013) Early de novo DNA methylation and prolonged demethylation in the muscle lineage. Epigenetics 8, 317-332.
-
(2013)
Epigenetics
, vol.8
, pp. 317-332
-
-
Tsumagari, K.1
Baribault, C.2
Terragni, J.3
Varley, K.E.4
Gertz, J.5
Pradhan, S.6
Badoo, M.7
Crain, C.M.8
Song, L.9
Crawford, G.E.10
-
125
-
-
84872867103
-
Histone H3K9 methyltransferase G9a represses PPARc expression and adipogenesis
-
Wang L, Xu S, Lee J-E, Baldridge A, Grullon S, Peng W, &, Ge K, (2012) Histone H3K9 methyltransferase G9a represses PPARc expression and adipogenesis. EMBO J 32, 45-59.
-
(2012)
EMBO J
, vol.32
, pp. 45-59
-
-
Wang, L.1
Xu, S.2
Lee, J.-E.3
Baldridge, A.4
Grullon, S.5
Peng, W.6
Ge, K.7
-
126
-
-
58049206724
-
Targeted inactivation of MLL3 histone H3-Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis
-
Lee J, Saha PK, Yang QH, Lee S, Park JY, Suh Y, Lee S-K, Lee SK, Chan L, Chan L, et al,. (2008) Targeted inactivation of MLL3 histone H3-Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis. Proc Natl Acad Sci USA 105, 19229-19234.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 19229-19234
-
-
Lee, J.1
Saha, P.K.2
Yang, Q.H.3
Lee, S.4
Park, J.Y.5
Suh, Y.6
Lee, S.-K.7
Lee, S.K.8
Chan, L.9
Chan, L.10
-
127
-
-
84896378030
-
DNA methylation is required for the control of stem cell differentiation in the small intestine
-
Sheaffer KL, Kim R, Aoki R, Elliott EN, Schug J, Burger L, Schübeler D, &, Kaestner KH, (2014) DNA methylation is required for the control of stem cell differentiation in the small intestine. Genes Dev 28, 652-664.
-
(2014)
Genes Dev
, vol.28
, pp. 652-664
-
-
Sheaffer, K.L.1
Kim, R.2
Aoki, R.3
Elliott, E.N.4
Schug, J.5
Burger, L.6
Schübeler, D.7
Kaestner, K.H.8
-
128
-
-
33645825196
-
Suppression of intestinal neoplasia by deletion of Dnmt3b
-
Lin H, Yamada Y, Nguyen S, Linhart H, Jackson-Grusby L, Meissner A, Meletis K, Lo G, &, Jaenisch R, (2006) Suppression of intestinal neoplasia by deletion of Dnmt3b. Mol Cell Biol 26, 2976-2983.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 2976-2983
-
-
Lin, H.1
Yamada, Y.2
Nguyen, S.3
Linhart, H.4
Jackson-Grusby, L.5
Meissner, A.6
Meletis, K.7
Lo, G.8
Jaenisch, R.9
-
129
-
-
36849004469
-
Dnmt3b promotes tumorigenesis in vivo by gene-specific de novo methylation and transcriptional silencing
-
Linhart HG, Lin H, Yamada Y, Moran E, Steine EJ, Gokhale S, Lo G, Cantu E, Ehrich M, He T, et al,. (2007) Dnmt3b promotes tumorigenesis in vivo by gene-specific de novo methylation and transcriptional silencing. Genes Dev 21, 3110-3122.
-
(2007)
Genes Dev
, vol.21
, pp. 3110-3122
-
-
Linhart, H.G.1
Lin, H.2
Yamada, Y.3
Moran, E.4
Steine, E.J.5
Gokhale, S.6
Lo, G.7
Cantu, E.8
Ehrich, M.9
He, T.10
-
130
-
-
84896691636
-
Broadly permissive intestinal chromatin underlies lateral inhibition and cell plasticity
-
Kim T-H, Li F, Ferreiro-Neira I, Ho L-L, Luyten A, Nalapareddy K, Long H, Verzi M, &, Shivdasani RA, (2014) Broadly permissive intestinal chromatin underlies lateral inhibition and cell plasticity. Nature 506, 511-515.
-
(2014)
Nature
, vol.506
, pp. 511-515
-
-
Kim, T.-H.1
Li, F.2
Ferreiro-Neira, I.3
Ho, L.-L.4
Luyten, A.5
Nalapareddy, K.6
Long, H.7
Verzi, M.8
Shivdasani, R.A.9
-
131
-
-
84875745673
-
Interplay between the cancer genome and epigenome
-
Shen H, &, Laird PW, (2013) Interplay between the cancer genome and epigenome. Cell 153, 38-55.
-
(2013)
Cell
, vol.153
, pp. 38-55
-
-
Shen, H.1
Laird, P.W.2
-
132
-
-
84886111619
-
DNA methylation age of human tissues and cell types
-
Horvath S, (2013) DNA methylation age of human tissues and cell types. Genome Biol 14, R115.
-
(2013)
Genome Biol
, vol.14
, pp. R115
-
-
Horvath, S.1
-
133
-
-
77955085750
-
Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders
-
Ernst T, Chase AJ, Score J, Hidalgo-Curtis CE, Bryant C, Jones AV, Waghorn K, Zoi K, Ross FM, Reiter A, et al,. (2010) Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders. Nat Genet 42, 722-726.
-
(2010)
Nat Genet
, vol.42
, pp. 722-726
-
-
Ernst, T.1
Chase, A.J.2
Score, J.3
Hidalgo-Curtis, C.E.4
Bryant, C.5
Jones, A.V.6
Waghorn, K.7
Zoi, K.8
Ross, F.M.9
Reiter, A.10
-
134
-
-
84857942952
-
Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing
-
Lohr JG, Stojanov P, Lawrence MS, Auclair D, Chapuy B, Sougnez C, Cruz-Gordillo P, Knoechel B, Asmann YW, Slager SL, et al,. (2012) Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing. Proc Natl Acad Sci USA 109, 3879-3884.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 3879-3884
-
-
Lohr, J.G.1
Stojanov, P.2
Lawrence, M.S.3
Auclair, D.4
Chapuy, B.5
Sougnez, C.6
Cruz-Gordillo, P.7
Knoechel, B.8
Asmann, Y.W.9
Slager, S.L.10
-
135
-
-
84863165348
-
Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27)
-
McCabe MT, Graves AP, Ganji G, Diaz E, Halsey WS, Jiang Y, Smitheman KN, Ott HM, Pappalardi MB, Allen KE, et al,. (2012) Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27). Proc Natl Acad Sci USA 109, 2989-2994.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 2989-2994
-
-
McCabe, M.T.1
Graves, A.P.2
Ganji, G.3
Diaz, E.4
Halsey, W.S.5
Jiang, Y.6
Smitheman, K.N.7
Ott, H.M.8
Pappalardi, M.B.9
Allen, K.E.10
-
136
-
-
77955087290
-
Somatic mutations of the histone methyltransferase gene EZH2 in myelodysplastic syndromes
-
Nikoloski G, Langemeijer SMC, Kuiper RP, Knops R, Massop M, Tönnissen ERLTM, van der Heijden A, Scheele TN, Vandenberghe P, de Witte T, et al,. (2010) Somatic mutations of the histone methyltransferase gene EZH2 in myelodysplastic syndromes. Nat Genet 42, 665-667.
-
(2010)
Nat Genet
, vol.42
, pp. 665-667
-
-
Nikoloski, G.1
Langemeijer, S.M.C.2
Kuiper, R.P.3
Knops, R.4
Massop, M.5
Tönnissen, E.6
Van Der Heijden, A.7
Scheele, T.N.8
Vandenberghe, P.9
De Witte, T.10
-
137
-
-
84870573126
-
EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations
-
McCabe MT, Ott HM, Ganji G, Korenchuk S, Thompson C, Van Aller GS, Liu Y, Graves AP, Pietra Della A III, Diaz E, et al,. (2013) EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations. Nature 492, 108-112.
-
(2013)
Nature
, vol.492
, pp. 108-112
-
-
McCabe, M.T.1
Ott, H.M.2
Ganji, G.3
Korenchuk, S.4
Thompson, C.5
Van Aller, G.S.6
Liu, Y.7
Graves, A.P.8
Pietra Della, A.9
Diaz, E.10
-
138
-
-
84884532954
-
Targeted disruption of the EZH2-EED complex inhibits EZH2-dependent cancer
-
Kim W, Bird GH, Neff T, Guo G, Kerenyi MA, Walensky LD, &, Orkin SH, (2013) Targeted disruption of the EZH2-EED complex inhibits EZH2-dependent cancer. Nat Chem Biol 9, 643-650.
-
(2013)
Nat Chem Biol
, vol.9
, pp. 643-650
-
-
Kim, W.1
Bird, G.H.2
Neff, T.3
Guo, G.4
Kerenyi, M.A.5
Walensky, L.D.6
Orkin, S.H.7
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