메뉴 건너뛰기




Volumn 31, Issue 3, 2012, Pages 616-629

The histone methyltransferase Setd8 acts in concert with c-Myc and is required to maintain skin

Author keywords

c Myc; Setd8 PR Set7 Set8 KMT5a; skin; stem cells

Indexed keywords

HISTONE METHYLTRANSFERASE; MYC PROTEIN; PROTEIN P53; PROTEIN P63; SETD8 ENZYME; UNCLASSIFIED DRUG;

EID: 84856449868     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2011.421     Document Type: Article
Times cited : (69)

References (63)
  • 1
    • 77957378110 scopus 로고    scopus 로고
    • CRL4(Cdt2) regulates cell proliferation and histone gene expression by targeting PR-Set7/Set8 for degradation
    • Abbas T, Shibata E, Park J, Jha S, Karnani N, Dutta A (2010) CRL4(Cdt2) regulates cell proliferation and histone gene expression by targeting PR-Set7/Set8 for degradation. Mol Cell 40: 9-21
    • (2010) Mol Cell , vol.40 , pp. 9-21
    • Abbas, T.1    Shibata, E.2    Park, J.3    Jha, S.4    Karnani, N.5    Dutta, A.6
  • 2
    • 78651395627 scopus 로고    scopus 로고
    • Exploring the 'hair growth-wound healing connection': Anagen phase promotes wound re-epithelialization
    • Ansell DM, Kloepper JE, Thomason HA, Paus R, Hardman MJ (2011) Exploring the 'hair growth-wound healing connection': anagen phase promotes wound re-epithelialization. J Invest Dermatol 131: 518-528
    • (2011) J Invest Dermatol , vol.131 , pp. 518-528
    • Ansell, D.M.1    Kloepper, J.E.2    Thomason, H.A.3    Paus, R.4    Hardman, M.J.5
  • 3
    • 0035901594 scopus 로고    scopus 로고
    • C-Myc activation in transgenic mouse epidermis results in mobilization of stem cells and differentiation of their progeny
    • DOI 10.1016/S0960-9822(01)00154-3
    • Arnold I, Watt FM (2001) c-Myc activation in transgenic mouse epidermis results in mobilization of stem cells and differentiation of their progeny. Curr Biol 11: 558-568 (Pubitemid 32324758)
    • (2001) Current Biology , vol.11 , Issue.8 , pp. 558-568
    • Arnold, I.1    Watt, F.M.2
  • 4
    • 34249026300 scopus 로고    scopus 로고
    • High-resolution profiling of histone methylations in the human genome
    • DOI 10.1016/j.cell.2007.05.009, PII S0092867407006009
    • Barski A, Cuddapah S, Cui K, Roh TY, Schones DE, Wang Z, Wei G, Chepelev I, Zhao K (2007) High-resolution profiling of histone methylations in the human genome. Cell 129: 823-837 (Pubitemid 46802390)
    • (2007) Cell , vol.129 , Issue.4 , pp. 823-837
    • Barski, A.1    Cuddapah, S.2    Cui, K.3    Roh, T.-Y.4    Schones, D.E.5    Wang, Z.6    Wei, G.7    Chepelev, I.8    Zhao, K.9
  • 5
    • 0032505758 scopus 로고    scopus 로고
    • Selection and extended growth of murine epidermal stem cells in culture
    • DOI 10.1006/excr.1998.4163
    • Bickenbach JR, Chism E (1998) Selection and extended growth of murine epidermal stem cells in culture. Exp Cell Res 244: 184-195 (Pubitemid 28480866)
    • (1998) Experimental Cell Research , vol.244 , Issue.1 , pp. 184-195
    • Bickenbach, J.R.1    Chism, E.2
  • 6
    • 60749125436 scopus 로고    scopus 로고
    • Epidermal homeostasis: A balancing act of stem cells in the skin
    • Blanpain C, Fuchs E (2009) Epidermal homeostasis: a balancing act of stem cells in the skin. Nat Rev Mol Cell Biol 10: 207-217
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 207-217
    • Blanpain, C.1    Fuchs, E.2
  • 7
    • 33845666681 scopus 로고    scopus 로고
    • Structural Basis for the Methylation State-Specific Recognition of Histone H4-K20 by 53BP1 and Crb2 in DNA Repair
    • DOI 10.1016/j.cell.2006.10.043, PII S009286740601525X
    • Botuyan MV, Lee J, Ward IM, Kim JE, Thompson JR, Chen J, Mer G (2006) Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair. Cell 127: 1361-1373 (Pubitemid 44960409)
    • (2006) Cell , vol.127 , Issue.7 , pp. 1361-1373
    • Botuyan, M.V.1    Lee, J.2    Ward, I.M.3    Kim, J.-E.4    Thompson, J.R.5    Chen, J.6    Mer, G.7
  • 8
    • 0242460440 scopus 로고    scopus 로고
    • Manipulation of stem cell proliferation and lineage commitment: Visualisation of label-retaining cells in wholemounts of mouse epidermis
    • DOI 10.1242/dev.00703
    • Braun KM, Niemann C, Jensen UB, Sundberg JP, Silva-Vargas V, Watt FM (2003) Manipulation of stem cell proliferation and lineage commitment: visualisation of label-retaining cells in whole mounts of mouse epidermis. Development (Cambridge, England) 130: 5241-5255 (Pubitemid 37369682)
    • (2003) Development , vol.130 , Issue.21 , pp. 5241-5255
    • Braun, K.M.1    Niemann, C.2    Jensen, U.B.3    Sundberg, J.P.4    Silva-Vargas, V.5    Watt, F.M.6
  • 10
    • 55749086013 scopus 로고    scopus 로고
    • Dynamic regulation of retinoic acidbinding proteins in developing, adult and neoplastic skin reveals roles for beta-catenin and Notch signalling
    • Collins CA, Watt FM (2008) Dynamic regulation of retinoic acidbinding proteins in developing, adult and neoplastic skin reveals roles for beta-catenin and Notch signalling. Dev Biol 324: 55-67
    • (2008) Dev Biol , vol.324 , pp. 55-67
    • Collins, C.A.1    Watt, F.M.2
  • 11
    • 0034601372 scopus 로고    scopus 로고
    • Switch from p53 to MDM2 as differentiating human keratinocytes lose their proliferative potential and increase in cellular size
    • Dazard JE, Piette J, Basset-Seguin N, Blanchard JM, Gandarillas A (2000) Switch from p53 to MDM2 as differentiating human keratinocytes lose their proliferative potential and increase in cellular size. Oncogene 19: 3693-3705 (Pubitemid 30621174)
    • (2000) Oncogene , vol.19 , Issue.33 , pp. 3693-3705
    • Dazard, J.-E.1    Piette, J.2    Basset-Seguin, N.3    Blanchard, J.-M.4    Gandarillas, A.5
  • 14
    • 79952220410 scopus 로고    scopus 로고
    • EZH1 and EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair
    • Ezhkova E, Lien WH, Stokes N, Pasolli HA, Silva JM, Fuchs E (2011) EZH1 and EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair. Genes Dev 25: 485-498
    • (2011) Genes Dev , vol.25 , pp. 485-498
    • Ezhkova, E.1    Lien, W.H.2    Stokes, N.3    Pasolli, H.A.4    Silva, J.M.5    Fuchs, E.6
  • 16
    • 34447625911 scopus 로고    scopus 로고
    • Epigenetics and aging: The targets and the marks
    • DOI 10.1016/j.tig.2007.05.008, PII S0168952507001862
    • Fraga MF, Esteller M (2007) Epigenetics and aging: the targets and the marks. Trends Genet 23: 413-418 (Pubitemid 47088010)
    • (2007) Trends in Genetics , vol.23 , Issue.8 , pp. 413-418
    • Fraga, M.F.1    Esteller, M.2
  • 17
    • 34848864644 scopus 로고    scopus 로고
    • Epidermal stem cells are defined by global histone modifications that are altered by Myc-induced differentiation
    • Frye M, Fisher AG, Watt FM (2007) Epidermal stem cells are defined by global histone modifications that are altered by Myc-induced differentiation. PLoS ONE 2: e763
    • (2007) PLoS ONE , vol.2
    • Frye, M.1    Fisher, A.G.2    Watt, F.M.3
  • 18
    • 0042913170 scopus 로고    scopus 로고
    • Evidence that Myc activation depletes the epidermal stem cell compartment by modulating adhesive interactions with the local microenvironment
    • DOI 10.1242/dev.00462
    • Frye M, Gardner C, Li ER, Arnold I, Watt FM (2003) Evidence that Myc activation depletes the epidermal stem cell compartment by modulating adhesive interactions with the local microenvironment. Development (Cambridge, England) 130: 2793-2808 (Pubitemid 37069593)
    • (2003) Development , vol.130 , Issue.12 , pp. 2793-2808
    • Frye, M.1    Gardner, C.2    Li, E.R.3    Arnold, I.4    Watt, F.M.5
  • 19
    • 65849401051 scopus 로고    scopus 로고
    • The tortoise and the hair: Slow-cycling cells in the stem cell race
    • Fuchs E (2009) The tortoise and the hair: slow-cycling cells in the stem cell race. Cell 137: 811-819
    • (2009) Cell , vol.137 , pp. 811-819
    • Fuchs, E.1
  • 20
    • 0030778620 scopus 로고    scopus 로고
    • C-Myc promotes differentiation of human epidermal stem cells
    • Gandarillas A, Watt FM (1997) c-Myc promotes differentiation of human epidermal stem cells. Genes Dev 11: 2869-2882 (Pubitemid 27481687)
    • (1997) Genes and Development , vol.11 , Issue.21 , pp. 2869-2882
    • Gandarillas, A.1    Watt, F.M.2
  • 21
    • 0034650682 scopus 로고    scopus 로고
    • Myc induces the nucleolin and BN51 genes: Possible implications in ribosome biogenesis
    • Greasley PJ, Bonnard C, Amati B (2000) Myc induces the nucleolin and BN51 genes: possible implications in ribosome biogenesis. Nucleic Acids Res 28: 446-453 (Pubitemid 30057983)
    • (2000) Nucleic Acids Research , vol.28 , Issue.2 , pp. 446-453
    • Greasley, P.J.1    Bonnard, C.2    Amati, B.3
  • 22
    • 0345304246 scopus 로고    scopus 로고
    • Positive and negative regulation of ΔN-p63 promoter activity by p53 and ΔN-p63-α contributes to differential regulation of p53 target genes
    • DOI 10.1038/sj.onc.1207129
    • Harmes DC, Bresnick E, Lubin EA, Watson JK, Heim KE, Curtin JC, Suskind AM, Lamb J, DiRenzo J (2003) Positive and negative regulation of deltaN-p63 promoter activity by p53 and deltaNp63-alpha contributes to differential regulation of p53 target genes. Oncogene 22: 7607-7616 (Pubitemid 37464094)
    • (2003) Oncogene , vol.22 , Issue.48 , pp. 7607-7616
    • Harmes, D.C.1    Bresnick, E.2    Lubin, E.A.3    Watson, J.K.4    Heim, K.E.5    Curtin, J.C.6    Suskind, A.M.7    Lamb, J.8    DiRenzo, J.9
  • 23
    • 50349085791 scopus 로고    scopus 로고
    • Catalytic function of the PR-Set7 histone H4 lysine 20 monomethyltransferase is essential for mitotic entry and genomic stability
    • Houston SI, McManus KJ, Adams MM, Sims JK, Carpenter PB, Hendzel MJ, Rice JC (2008) Catalytic function of the PR-Set7 histone H4 lysine 20 monomethyltransferase is essential for mitotic entry and genomic stability. J Biol Chem 283: 19478-19488
    • (2008) J Biol Chem , vol.283 , pp. 19478-19488
    • Houston, S.I.1    McManus, K.J.2    Adams, M.M.3    Sims, J.K.4    Carpenter, P.B.5    Hendzel, M.J.6    Rice, J.C.7
  • 24
    • 45549087777 scopus 로고    scopus 로고
    • Direct interaction between SET8 and proliferating cell nuclear antigen couples H4-K20 methylation with DNA replication
    • Huen MS, Sy SM, van Deursen JM, Chen J (2008) Direct interaction between SET8 and proliferating cell nuclear antigen couples H4-K20 methylation with DNA replication. J Biol Chem 283: 11073-11077
    • (2008) J Biol Chem , vol.283 , pp. 11073-11077
    • Huen, M.S.1    Sy, S.M.2    Van Deursen, J.M.3    Chen, J.4
  • 26
    • 28644451449 scopus 로고    scopus 로고
    • Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis
    • DOI 10.1038/nm1328
    • Ito M, Liu Y, Yang Z, Nguyen J, Liang F, Morris RJ, Cotsarelis G (2005) Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis. Nat Med 11: 1351-1354 (Pubitemid 41752917)
    • (2005) Nature Medicine , vol.11 , Issue.12 , pp. 1351-1354
    • Ito, M.1    Liu, Y.2    Yang, Z.3    Nguyen, J.4    Liang, F.5    Morris, R.J.6    Cotsarelis, G.7
  • 28
    • 77955489664 scopus 로고    scopus 로고
    • Assaying proliferation and differentiation capacity of stem cells using disaggregated adult mouse epidermis
    • Jensen KB, Driskell RR, Watt FM (2010) Assaying proliferation and differentiation capacity of stem cells using disaggregated adult mouse epidermis. Nat Protoc 5: 898-911
    • (2010) Nat Protoc , vol.5 , pp. 898-911
    • Jensen, K.B.1    Driskell, R.R.2    Watt, F.M.3
  • 31
    • 13844269327 scopus 로고    scopus 로고
    • PR-Set7-dependent methylation of histone H4 Lys 20 functions in repression of gene expression and is essential for mitosis
    • DOI 10.1101/gad.1263005
    • Karachentsev D, Sarma K, Reinberg D, Steward R (2005) PR-Set7-dependent methylation of histone H4 Lys 20 functions in repression of gene expression and is essential for mitosis. Genes Dev 19: 431-435 (Pubitemid 40256274)
    • (2005) Genes and Development , vol.19 , Issue.4 , pp. 431-435
    • Karachentsev, D.1    Sarma, K.2    Reinberg, D.3    Steward, R.4
  • 32
    • 0034737405 scopus 로고    scopus 로고
    • A novel reporter mouse strain that expresses enhanced green fluorescent protein upon Cre-mediated recombination
    • DOI 10.1016/S0014-5793(00)01338-7, PII S0014579300013387
    • Kawamoto S, Niwa H, Tashiro F, Sano S, Kondoh G, Takeda J, Tabayashi K, Miyazaki J (2000) A novel reporter mouse strain that expresses enhanced green fluorescent protein upon Cre-mediated recombination. FEBS Lett 470: 263-268 (Pubitemid 30169275)
    • (2000) FEBS Letters , vol.470 , Issue.3 , pp. 263-268
    • Kawamoto, S.1    Niwa, H.2    Tashiro, F.3    Sano, S.4    Kondoh, G.5    Takeda, J.6    Tabayashi, K.7    Miyazaki, J.-I.8
  • 33
    • 77956880485 scopus 로고    scopus 로고
    • P63 in skin development and ectodermal dysplasias
    • Koster MI (2010) p63 in skin development and ectodermal dysplasias. J Invest Dermatol 130: 2352-2358
    • (2010) J Invest Dermatol , vol.130 , pp. 2352-2358
    • Koster, M.I.1
  • 34
    • 79954577502 scopus 로고    scopus 로고
    • The histone modifications governing TFF1 transcription mediated by estrogen receptor
    • Li Y, Sun L, Zhang Y, Wang D, Wang F, Liang J, Gui B, Shang Y (2011a) The histone modifications governing TFF1 transcription mediated by estrogen receptor. J Biol Chem 286: 13925-13936
    • (2011) J Biol Chem , vol.286 , pp. 13925-13936
    • Li, Y.1    Sun, L.2    Zhang, Y.3    Wang, D.4    Wang, F.5    Liang, J.6    Gui, B.7    Shang, Y.8
  • 35
    • 79952762476 scopus 로고    scopus 로고
    • From the Cover: Feature Article: Histone H4 Lys 20 monomethylation by histone methylase SET8 mediates Wnt target gene activation
    • Li Z, Nie F, Wang S, Li L (2011b) From the Cover: Feature Article: Histone H4 Lys 20 monomethylation by histone methylase SET8 mediates Wnt target gene activation. Proc Natl Acad Sci USA 108: 3116-3123
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 3116-3123
    • Li, Z.1    Nie, F.2    Wang, S.3    Li, L.4
  • 36
    • 0033881433 scopus 로고    scopus 로고
    • Down-regulation of p63 is required for epidermal UV-B-induced apoptosis
    • Liefer KM, Koster MI, Wang XJ, Yang A, McKeon F, Roop DR (2000) Down-regulation of p63 is required for epidermal UV-B-induced apoptosis. Cancer Res 60: 4016-4020 (Pubitemid 30636575)
    • (2000) Cancer Research , vol.60 , Issue.15 , pp. 4016-4020
    • Liefer, K.M.1    Koster, M.I.2    Wang, X.-J.3    Yang, A.4    McKeon, F.5    Roop, D.R.6
  • 37
    • 47949125557 scopus 로고    scopus 로고
    • Characterization of bipotential epidermal progenitors derived from human sebaceous gland: Contrasting roles of c-Myc and beta-catenin
    • Lo Celso C, Berta MA, Braun KM, Frye M, Lyle S, Zouboulis CC, Watt FM (2008) Characterization of bipotential epidermal progenitors derived from human sebaceous gland: contrasting roles of c-Myc and beta-catenin. Stem Cells (Dayton, Ohio) 26: 1241-1252
    • (2008) Stem Cells (Dayton, Ohio) , vol.26 , pp. 1241-1252
    • Lo Celso, C.1    Berta, M.A.2    Braun, K.M.3    Frye, M.4    Lyle, S.5    Zouboulis, C.C.6    Watt, F.M.7
  • 38
    • 0033594491 scopus 로고    scopus 로고
    • P63 is a p53 homologue required for limb and epidermal morphogenesis
    • DOI 10.1038/19531
    • Mills AA, Zheng B, Wang XJ, Vogel H, Roop DR, Bradley A (1999) p63 is a p53 homologue required for limb and epidermal morphogenesis. Nature 398: 708-713 (Pubitemid 29197649)
    • (1999) Nature , vol.398 , Issue.6729 , pp. 708-713
    • Mills, A.A.1    Zheng, B.2    Wang, X.-J.3    Vogel, H.4    Roop, D.R.5    Bradley, A.6
  • 39
    • 0021678279 scopus 로고
    • Identification of Merkel cells in human skin by specific cytokeratin antibodies: Changes of cell density and distribution in fetal and adult plantar epidermis
    • DOI 10.1111/j.1432-0436.1984.tb00277.x
    • Moll R, Moll I, Franke WW (1984) Identification of Merkel cells in human skin by specific cytokeratin antibodies: changes of cell density and distribution in fetal and adult plantar epidermis. Differentiation 28: 136-154 (Pubitemid 15167878)
    • (1984) Differentiation , vol.28 , Issue.2 , pp. 136-154
    • Moll, R.1    Moll, I.2    Franke, W.W.3
  • 41
    • 78149423004 scopus 로고    scopus 로고
    • Regulation of the histone H4 monomethylase PR-Set7 by CRL4(Cdt2)-mediated PCNA-dependent degradation during DNA damage
    • Oda H, Hubner MR, Beck DB, Vermeulen M, Hurwitz J, Spector DL, Reinberg D (2010) Regulation of the histone H4 monomethylase PR-Set7 by CRL4(Cdt2)-mediated PCNA-dependent degradation during DNA damage. Mol Cell 40: 364-376
    • (2010) Mol Cell , vol.40 , pp. 364-376
    • Oda, H.1    Hubner, M.R.2    Beck, D.B.3    Vermeulen, M.4    Hurwitz, J.5    Spector, D.L.6    Reinberg, D.7
  • 42
    • 64749106929 scopus 로고    scopus 로고
    • Monomethylation of histone H4-lysine 20 is involved in chromosome structure and stability and is essential for mouse development
    • Oda H, Okamoto I, Murphy N, Chu J, Price SM, Shen MM, Torres-Padilla ME, Heard E, Reinberg D (2009) Monomethylation of histone H4-lysine 20 is involved in chromosome structure and stability and is essential for mouse development. Mol Cell Biol 29: 2278-2295
    • (2009) Mol Cell Biol , vol.29 , pp. 2278-2295
    • Oda, H.1    Okamoto, I.2    Murphy, N.3    Chu, J.4    Price, S.M.5    Shen, M.M.6    Torres-Padilla, M.E.7    Heard, E.8    Reinberg, D.9
  • 43
    • 0036714189 scopus 로고    scopus 로고
    • Mitotic-specific methylation of histone H4 Lys 20 follows increased PR-Set7 expression and its localization to mitotic chromosomes
    • DOI 10.1101/gad.1014902
    • Rice JC, Nishioka K, Sarma K, Steward R, Reinberg D, Allis CD (2002) Mitotic-specific methylation of histone H4 Lys 20 follows increased PR-Set7 expression and its localization to mitotic chromosomes. Genes Dev 16: 2225-2230 (Pubitemid 35013085)
    • (2002) Genes and Development , vol.16 , Issue.17 , pp. 2225-2230
    • Rice, J.C.1    Nishioka, K.2    Sarma, K.3    Steward, R.4    Reinberg, D.5    David Allis, C.6
  • 44
    • 77954830569 scopus 로고    scopus 로고
    • Setting and resetting of epigenetic marks in malignant transformation and development
    • Richly H, Lange M, Simboeck E, Di Croce L (2010) Setting and resetting of epigenetic marks in malignant transformation and development. Bioessays 32: 669-679
    • (2010) Bioessays , vol.32 , pp. 669-679
    • Richly, H.1    Lange, M.2    Simboeck, E.3    Di Croce, L.4
  • 45
    • 8844248619 scopus 로고    scopus 로고
    • Methylation of histone H4 lysine 20 controls recruitment of Crb2 to sites of DNA damage
    • DOI 10.1016/j.cell.2004.11.009, PII S0092867404010530
    • Sanders SL, Portoso M, Mata J, Bahler J, Allshire RC, Kouzarides T (2004) Methylation of histone H4 lysine 20 controls recruitment of Crb2 to sites of DNA damage. Cell 119: 603-614 (Pubitemid 39535749)
    • (2004) Cell , vol.119 , Issue.5 , pp. 603-614
    • Sanders, S.L.1    Portoso, M.2    Mata, J.3    Bahler, J.4    Allshire, R.C.5    Kouzarides, T.6
  • 47
    • 57549089243 scopus 로고    scopus 로고
    • Using TESS to predict transcription factor binding sites in DNA sequence
    • Unit 2.6
    • Schug J (2008) Using TESS to predict transcription factor binding sites in DNA sequence. Curr Protoc Bioinformatics Chapter 2: Unit 2.6
    • (2008) Curr Protoc Bioinformatics Chapter , vol.2
    • Schug, J.1
  • 48
    • 0023263034 scopus 로고
    • Selective suppression of two postnatally acquired 70 kD and 65 kD keratin proteins during continuous treatment of adult mouse tail epidermis with vitamin A
    • Schweizer J, Furstenberger G, Winter H (1987) Selective suppression of two postnatally acquired 70 kD and 65 kD keratin proteins during continuous treatment of adult mouse tail epidermis with vitamin A. J Invest Dermatol 89: 125-131 (Pubitemid 17105186)
    • (1987) Journal of Investigative Dermatology , vol.89 , Issue.2 , pp. 125-131
    • Schweizer, J.1    Furstenberger, G.2    Winter, H.3
  • 49
    • 47549105128 scopus 로고    scopus 로고
    • Control of differentiation in a self-renewing mammalian tissue by the histone demethylase JMJD3
    • DOI 10.1101/gad.1673508
    • Sen GL, Webster DE, Barragan DI, Chang HY, Khavari PA (2008) Control of differentiation in a self-renewing mammalian tissue by the histone demethylase JMJD3. Genes Dev 22: 1865-1870 (Pubitemid 352008635)
    • (2008) Genes and Development , vol.22 , Issue.14 , pp. 1865-1870
    • Sen, G.L.1    Webster, D.E.2    Barragan, D.I.3    Chang, H.Y.4    Khavari, P.A.5
  • 50
    • 34247511981 scopus 로고    scopus 로고
    • P63 Is essential for the proliferative potential of stem cells in stratified epithelia
    • DOI 10.1016/j.cell.2007.02.045, PII S0092867407003844
    • Senoo M, Pinto F, Crum CP, McKeon F (2007) p63 Is essential for the proliferative potential of stem cells in stratified epithelia. Cell 129: 523-536 (Pubitemid 46660965)
    • (2007) Cell , vol.129 , Issue.3 , pp. 523-536
    • Senoo, M.1    Pinto, F.2    Crum, C.P.3    McKeon, F.4
  • 51
    • 77956659869 scopus 로고    scopus 로고
    • Returning to the stem state: Epigenetics of recapitulating pre-differentiation chromatin structure
    • Shafa M, Krawetz R, Rancourt DE (2010) Returning to the stem state: epigenetics of recapitulating pre-differentiation chromatin structure. Bioessays 32: 791-799
    • (2010) Bioessays , vol.32 , pp. 791-799
    • Shafa, M.1    Krawetz, R.2    Rancourt, D.E.3
  • 53
    • 78149281634 scopus 로고    scopus 로고
    • The histone H4 Lys 20 methyltransferase PR-Set7 regulates replication origins in mammalian cells
    • Tardat M, Brustel J, Kirsh O, Lefevbre C, Callanan M, Sardet C, Julien E (2010) The histone H4 Lys 20 methyltransferase PR-Set7 regulates replication origins in mammalian cells. Nat Cell Biol 12: 1086-1093
    • (2010) Nat Cell Biol , vol.12 , pp. 1086-1093
    • Tardat, M.1    Brustel, J.2    Kirsh, O.3    Lefevbre, C.4    Callanan, M.5    Sardet, C.6    Julien, E.7
  • 54
    • 38049025837 scopus 로고    scopus 로고
    • PR-Set7-dependent lysine methylation ensures genome replication and stability through S phase
    • Tardat M, Murr R, Herceg Z, Sardet C, Julien E (2007) PR-Set7-dependent lysine methylation ensures genome replication and stability through S phase. J Cell Biol 179: 1413-1426
    • (2007) J Cell Biol , vol.179 , pp. 1413-1426
    • Tardat, M.1    Murr, R.2    Herceg, Z.3    Sardet, C.4    Julien, E.5
  • 55
    • 33751230475 scopus 로고    scopus 로고
    • P63 regulates proliferation and differentiation of developmentally mature keratinocytes
    • DOI 10.1101/gad.1463206
    • Truong AB, Kretz M, Ridky TW, Kimmel R, Khavari PA (2006) p63 regulates proliferation and differentiation of developmentally mature keratinocytes. Genes Dev 20: 3185-3197 (Pubitemid 44790632)
    • (2006) Genes and Development , vol.20 , Issue.22 , pp. 3185-3197
    • Truong, A.B.1    Kretz, M.2    Ridky, T.W.3    Kimmel, R.4    Khavari, P.A.5
  • 56
    • 33845451555 scopus 로고    scopus 로고
    • Profile of histone lysine methylation across transcribed mammalian chromatin
    • DOI 10.1128/MCB.01529-06
    • Vakoc CR, Sachdeva MM, Wang H, Blobel GA (2006) Profile of histone lysine methylation across transcribed mammalian chromatin. Mol Cell Biol 26: 9185-9195 (Pubitemid 44904415)
    • (2006) Molecular and Cellular Biology , vol.26 , Issue.24 , pp. 9185-9195
    • Vakoc, C.R.1    Sachdeva, M.M.2    Wang, H.3    Blobel, G.A.4
  • 58
    • 39749124274 scopus 로고    scopus 로고
    • MYC in mammalian epidermis: How can an oncogene stimulate differentiation?
    • DOI 10.1038/nrc2328, PII NRC2328
    • Watt FM, Frye M, Benitah SA (2008) MYC in mammalian epidermis: how can an oncogene stimulate differentiation? Nat Rev 8: 234-242 (Pubitemid 351301841)
    • (2008) Nature Reviews Cancer , vol.8 , Issue.3 , pp. 234-242
    • Watt, F.M.1    Frye, M.2    Benitah, S.A.3
  • 59
    • 77449119710 scopus 로고    scopus 로고
    • Epidermal stem cell diversity and quiescence
    • Watt FM, Jensen KB (2009) Epidermal stem cell diversity and quiescence. EMBO Mol Med 1: 260-267
    • (2009) EMBO Mol Med , vol.1 , pp. 260-267
    • Watt, F.M.1    Jensen, K.B.2
  • 60
    • 0037377761 scopus 로고    scopus 로고
    • The ΔNp63α phosphoprotein binds the p21 and 14-3-3σ promoters in vivo and has transcriptional repressor activity that is reduced by Hay-Wells syndrome-derived mutations
    • DOI 10.1128/MCB.23.7.2264-2276.2003
    • Westfall MD, Mays DJ, Sniezek JC, Pietenpol JA (2003) The Delta Np63 alpha phosphoprotein binds the p21 and 14-3-3 sigma promoters in vivo and has transcriptional repressor activity that is reduced by Hay-Wells syndrome-derived mutations. Mol Cell Biol 23: 2264-2276 (Pubitemid 36351010)
    • (2003) Molecular and Cellular Biology , vol.23 , Issue.7 , pp. 2264-2276
    • Westfall, M.D.1    Mays, D.J.2    Sniezek, J.C.3    Pietenpol, J.A.4
  • 62
    • 0032161624 scopus 로고    scopus 로고
    • P63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities
    • Yang A, Kaghad M, Wang Y, Gillett E, Fleming MD, Dotsch V, Andrews NC, Caput D, McKeon F (1998) p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities. Mol Cell 2: 305-316 (Pubitemid 128379271)
    • (1998) Molecular Cell , vol.2 , Issue.3 , pp. 305-316
    • Yang, A.1    Kaghad, M.2    Wang, Y.3    Gillett, E.4    Fleming, M.D.5    Dotsch, V.6    Andrews, N.C.7    Caput, D.8    McKeon, F.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.