Evidence that Myc activation depletes the epidermal stem cell compartment by modulating adhesive interactions with the local microenvironment

Development

Volumn 130, Issue 12, 2003, Pages 2793-2808

  Frye, Michaela ^a   Gardner, Clare ^b   Li, Elizabeth R ^a   Arnold, Isabel ^a,c   Watt, Fiona M ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

^c UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Cell adhesion; Differentiation; Epidermis; Myc; Stem cells

Indexed keywords

ACTIN; CYTOSKELETON PROTEIN; INTEGRIN; MYC PROTEIN; MYOSIN; SCLEROPROTEIN;

ANIMAL CELL; ANIMAL TISSUE; CELL ADHESION; CELL DIFFERENTIATION; CELL INTERACTION; CELL LINEAGE; CELL MIGRATION; CELL MOTILITY; CELL PROLIFERATION; CELL SPREADING; CONTROLLED STUDY; DOWN REGULATION; EPIDERMIS; EPIDERMIS CELL; GENE ACTIVATION; GENE CONTROL; GENE INDUCTION; GENE REPRESSION; GENETIC TRANSCRIPTION; HAIR CELL; HAIR ROOT; HEMIDESMOSOME; HUMAN; HUMAN CELL; KERATINOCYTE; MICROENVIRONMENT; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; ONCOGENE C MYC; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROCESSING; PROTEIN SYNTHESIS; REVIEW; RNA PROCESSING; RNA SYNTHESIS; STEM CELL; WOUND HEALING; ANIMAL; ARTICLE; CELL DIVISION; DNA MICROARRAY; EXTRACELLULAR MATRIX; GENE EXPRESSION REGULATION; METABOLISM; ONCOGENE MYC; PHYSIOLOGY; PRENATAL DEVELOPMENT; TRANSGENIC MOUSE; UPREGULATION;

ANIMALIA;

ANIMALS; CELL ADHESION; CELL DIFFERENTIATION; CELL DIVISION; EPIDERMIS; EXTRACELLULAR MATRIX; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, MYC; MICE; MICE, TRANSGENIC; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; STEM CELLS; UP-REGULATION; WOUND HEALING;

EID: 0042913170     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: 10.1242/dev.00462     Document Type: Review

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