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Volumn 131, Issue 6, 2011, Pages 1196-1207

P63, a story of mice and men

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53; PROTEIN P63; PROTEIN P73;

EID: 79956033054     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2011.84     Document Type: Note
Times cited : (149)

References (114)
  • 2
    • 63049136592 scopus 로고    scopus 로고
    • A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis
    • Adorno M, Cordenonsi M, Montagner M et al. (2009) A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis. Cell 137:87-98
    • (2009) Cell , vol.137 , pp. 87-98
    • Adorno, M.1    Cordenonsi, M.2    Montagner, M.3
  • 4
    • 77952886672 scopus 로고    scopus 로고
    • A genome-wide association study of cleft lip with and without cleft palate identifies risk variants near MAFB and ABCA4
    • Beaty TH, Murray JC, Marazita ML et al. (2010) A genome-wide association study of cleft lip with and without cleft palate identifies risk variants near MAFB and ABCA4. Nat Genet 42:525-9
    • (2010) Nat Genet , vol.42 , pp. 525-529
    • Beaty, T.H.1    Murray, J.C.2    Marazita, M.L.3
  • 5
    • 3242710577 scopus 로고    scopus 로고
    • Molecular evidence that AEC syndrome and Rapp-Hodgkin syndrome are variable expression of a single genetic disorder
    • DOI 10.1111/j.0009-9163.2004.00278.x
    • Bertola DR, Kim CA, Albano LM et al. (2004) Molecular evidence that AEC syndrome and Rapp-Hodgkin syndrome are variable expression of a single genetic disorder. Clin Genet 66:79-80 (Pubitemid 38960826)
    • (2004) Clinical Genetics , vol.66 , Issue.1 , pp. 79-80
    • Bertola, D.R.1    Kim, C.A.2    Albano, L.M.J.3    Scheffer, H.4    Meijer, R.5    Van Bokhoven, H.6
  • 6
    • 34250188106 scopus 로고    scopus 로고
    • Novel in vivo targets of DeltaNp63 in keratinocytes identified by a modified chromatin immunopreci-pitation approach
    • Birkaya B, Ortt K, Sinha S (2007) Novel in vivo targets of DeltaNp63 in keratinocytes identified by a modified chromatin immunopreci-pitation approach. BMC Mol Biol 8:43
    • (2007) BMC Mol Biol , vol.8 , pp. 43
    • Birkaya, B.1    Ortt, K.2    Sinha, S.3
  • 7
    • 60749125436 scopus 로고    scopus 로고
    • Epidermal home-ostasis: A balancing act of stem cells in the skin
    • Blanpain C, Fuchs E (2009) Epidermal home-ostasis: a balancing act of stem cells in the skin. Nat Rev Mol Cell Biol 10:207-17
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 207-217
    • Blanpain, C.1    Fuchs, E.2
  • 9
    • 33847023954 scopus 로고    scopus 로고
    • TAp63 and DeltaNp63 in cancer and epidermal development
    • Candi E, Dinsdale D, Rufini A et al. (2007a) TAp63 and DeltaNp63 in cancer and epidermal development. Cell Cycle 6:274-85
    • (2007) Cell Cycle , vol.6 , pp. 274-285
    • Candi, E.1    Dinsdale, D.2    Rufini, A.3
  • 10
    • 33646797744 scopus 로고    scopus 로고
    • Differential roles of p63 isoforms in epidermal development: Selective genetic complementation in p63 null mice
    • Candi E, Rufini A, Terrinoni A et al. (2006a) Differential roles of p63 isoforms in epidermal development: selective genetic complementation in p63 null mice. Cell Death Differ 13:1037-47
    • (2006) Cell Death Differ , vol.13 , pp. 1037-1047
    • Candi, E.1    Rufini, A.2    Terrinoni, A.3
  • 18
    • 0030040451 scopus 로고    scopus 로고
    • Terminal deletion of the long arm of chromosome 3 [46,XX,del(3)(q27-qter) ]
    • Chitayat D, Babul R, Silver MM et al. (1996) Terminal deletion of the long arm of chromosome 3 [46,XX,del(3)(q27-qter)]. Am J Med Genet 61:45-8
    • (1996) Am J Med Genet , vol.61 , pp. 45-48
    • Chitayat, D.1    Babul, R.2    Silver, M.M.3
  • 19
    • 77954148376 scopus 로고    scopus 로고
    • DeltaNp63 transcriptionally regulates brachyury, a gene with diverse roles in limb development, tumorigenesis and metastasis
    • Cho MS, Chan IL, Flores ER (2010) DeltaNp63 transcriptionally regulates brachyury, a gene with diverse roles in limb development, tumorigenesis and metastasis. Cell Cycle 9: 2434-41
    • (2010) Cell Cycle , vol.9 , pp. 2434-2441
    • Cho, M.S.1    Chan, I.L.2    Flores, E.R.3
  • 20
    • 77955867266 scopus 로고    scopus 로고
    • Rapp-Hodgkin and Hay-Wells ecto-dermal dysplasia syndromes represent a variable spectrum of the same genetic disorder
    • Clements SE, Techanukul T, Holden ST et al. (2010) Rapp-Hodgkin and Hay-Wells ecto-dermal dysplasia syndromes represent a variable spectrum of the same genetic disorder. Br J Dermatol 163:624-9
    • (2010) Br J Dermatol , vol.163 , pp. 624-629
    • Clements, S.E.1    Techanukul, T.2    Holden, S.T.3
  • 21
    • 77952238224 scopus 로고    scopus 로고
    • P53-family proteins and their regulators: Hubs and spokes in tumor suppression
    • Collavin L, Lunardi A, Del Sal G (2010) p53-family proteins and their regulators: hubs and spokes in tumor suppression. Cell Death Differ 17:901-11
    • (2010) Cell Death Differ , vol.17 , pp. 901-911
    • Collavin, L.1    Lunardi, A.2    Del Sal, G.3
  • 22
    • 77949894769 scopus 로고    scopus 로고
    • P63 in epithelial survival, germ cell surveillance, and neopla-sia
    • Crum CP, McKeon FD (2010) p63 in epithelial survival, germ cell surveillance, and neopla-sia. Annu Rev Pathol 5:349-71
    • (2010) Annu Rev Pathol , vol.5 , pp. 349-371
    • Crum, C.P.1    McKeon, F.D.2
  • 23
    • 77951255398 scopus 로고    scopus 로고
    • P63 short isoforms are found in invasive carcinomas only and not in benign breast conditions
    • De Biase D, Morandi L, Degli Esposti R et al. (2010) p63 short isoforms are found in invasive carcinomas only and not in benign breast conditions. Virchows Arch 456:395-401
    • (2010) Virchows Arch , vol.456 , pp. 395-401
    • De Biase, D.1    Morandi, L.2    Degli Esposti, R.3
  • 27
    • 34547753615 scopus 로고    scopus 로고
    • P63 and p73 in human cancer: Defining the network
    • DOI 10.1038/sj.onc.1210337, PII 1210337
    • Deyoung MP, Ellisen LW (2007) p63 and p73 in human cancer: defining the network. Onco-gene 26:5169-83 (Pubitemid 47237632)
    • (2007) Oncogene , vol.26 , Issue.36 , pp. 5169-5183
    • DeYoung, M.P.1    Ellisen, L.W.2
  • 28
    • 1542647605 scopus 로고    scopus 로고
    • Rapp-Hodgkin and AEC syndromes due to a new frameshift mutation in the TP63 gene
    • Dianzani I, Garelli E, Gustavsson P et al. (2003) Rapp-Hodgkin and AEC syndromes due to a new frameshift mutation in the TP63 gene. J Med Genet 40:e133
    • (2003) J Med Genet , vol.40
    • Dianzani, I.1    Garelli, E.2    Gustavsson, P.3
  • 29
    • 0034743628 scopus 로고    scopus 로고
    • P63α and ΔNp63α can induce cell cycle arrest and apoptosis and differentially regulate p53 target genes
    • DOI 10.1038/sj.onc.1204427
    • Dohn M, Zhang S, Chen X (2001) p63alpha and DeltaNp63alpha can induce cell cycle arrest and apoptosis and differentially regulate p53 target genes. Oncogene 20:3193-205 (Pubitemid 32553672)
    • (2001) Oncogene , vol.20 , Issue.25 , pp. 3193-3205
    • Dohn, M.1    Zhang, S.2    Chen, X.3
  • 30
    • 0037387599 scopus 로고    scopus 로고
    • Pathogenesis of split-hand/split-foot malformation
    • Duijf PH, Van Bokhoven H, Brunner HG (2003) Pathogenesis of split-hand/split-foot malformation. Hum Mol Genet 12 Spec No 1:R51-60
    • (2003) Hum Mol Genet , vol.12 , Issue.1
    • Duijf, P.H.1    Van Bokhoven, H.2    Brunner, H.G.3
  • 32
    • 19944432702 scopus 로고    scopus 로고
    • Fine mapping of the X-linked split-hand/split-foot malformation (SHFM2) locus to a 5.1-Mb region on Xq26.3 and analysis of candidate genes
    • Faiyaz-Ul-Haque M, Zaidi SH, King LM et al. (2005) Fine mapping of the X-linked split-hand/split-foot malformation (SHFM2) locus to a 5.1-Mb region on Xq26.3 and analysis of candidate genes. Clin Genet 67:93-7
    • (2005) Clin Genet , vol.67 , pp. 93-97
    • Faiyaz-Ul-Haque, M.1    Zaidi, S.H.2    King, L.M.3
  • 33
    • 33847048245 scopus 로고    scopus 로고
    • The roles of p63 in cancer
    • Flores ER (2007) The roles of p63 in cancer. Cell Cycle 6:300-4
    • (2007) Cell Cycle , vol.6 , pp. 300-304
    • Flores, E.R.1
  • 36
    • 70350506325 scopus 로고    scopus 로고
    • Inhibition of the c-Abl-TAp63 pathway protects mouse oocytes from chemotherapy-induced death
    • Gonfloni S, Di Tella L, Caldarola S et al. (2009) Inhibition of the c-Abl-TAp63 pathway protects mouse oocytes from chemotherapy-induced death. Nat Med 15:1179-85
    • (2009) Nat Med , vol.15 , pp. 1179-1185
    • Gonfloni, S.1    Di Tella, L.2    Caldarola, S.3
  • 38
    • 77951862285 scopus 로고    scopus 로고
    • P63 and IRF6: Brothers in arms against cleft palate
    • Gritli-Linde A (2010) p63 and IRF6: brothers in arms against cleft palate. J Clin Invest 120:1386-9
    • (2010) J Clin Invest , vol.120 , pp. 1386-1389
    • Gritli-Linde, A.1
  • 39
    • 73349088166 scopus 로고    scopus 로고
    • TAp63 induces senescence and suppresses tumorigenesis in vivo
    • Guo X, Keyes WM, Papazoglu C et al. (2009) TAp63 induces senescence and suppresses tumorigenesis in vivo. Nat Cell Biol 11:1451-7
    • (2009) Nat Cell Biol , vol.11 , pp. 1451-1457
    • Guo, X.1    Keyes, W.M.2    Papazoglu, C.3
  • 40
    • 33646365381 scopus 로고    scopus 로고
    • 2-terminally deleted (ΔN) residues, the PXXP motif, and the PPXY motif are required for the transcriptional activity of the ΔN variant of p63
    • DOI 10.1074/jbc.M507964200
    • Helton ES, Zhu J, Chen X (2006) The unique NH2-terminally deleted (DeltaN) residues, the PXXP motif, and the PPXY motif are required for the transcriptional activity of the DeltaN variant of p63. J Biol Chem 281:2533-42 (Pubitemid 43845713)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.5 , pp. 2533-2542
    • Helton, E.S.1    Zhu, J.2    Chen, X.3
  • 41
    • 0033537767 scopus 로고    scopus 로고
    • Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of Ikap-paB kinase
    • Hu Y, Baud V, Delhase M et al. (1999) Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of Ikap-paB kinase. Science 284:316-20
    • (1999) Science , vol.284 , pp. 316-320
    • Hu, Y.1    Baud, V.2    Delhase, M.3
  • 42
    • 0035809983 scopus 로고    scopus 로고
    • IKKα controls formation of the epidermis independently of NF-κB
    • DOI 10.1038/35070605
    • Hu Y, Baud V, Oga T et al. (2001) IKKalpha controls formation of the epidermis independently of NF-kappaB. Nature 410:710-4 (Pubitemid 32290360)
    • (2001) Nature , vol.410 , Issue.6829 , pp. 710-714
    • Hu, Y.1    Baud, V.2    Oga, T.3    Kim, K.I.4    Yoshida, K.5    Karin, M.6
  • 46
    • 69249088571 scopus 로고    scopus 로고
    • Rationale and background as basis for a new classification of the ectodermal dysplasias
    • Itin PH (2009) Rationale and background as basis for a new classification of the ectodermal dysplasias. Am J Med Genet A 149A:1973-6
    • (2009) Am J Med Genet A , vol.149 A , pp. 1973-1976
    • Itin, P.H.1
  • 47
    • 33645578950 scopus 로고    scopus 로고
    • Rapp-Hodgkin ectodermal dysplasia syndrome: The clinical and molecular overlap with Hay-Wells syndrome
    • Kannu P, Savarirayan R, Ozoemena L et al. (2006) Rapp-Hodgkin ectodermal dysplasia syndrome: the clinical and molecular overlap with Hay-Wells syndrome. Am J Med Genet A 140:887-91
    • (2006) Am J Med Genet A , vol.140 , pp. 887-891
    • Kannu, P.1    Savarirayan, R.2    Ozoemena, L.3
  • 48
    • 0037493688 scopus 로고    scopus 로고
    • Heterozygous mutation in the SAM domain of p63 underlies Rapp-Hodgkin ectodermal dysplasia
    • Kantaputra PN, Hamada T, Kumchai T et al. (2003) Heterozygous mutation in the SAM domain of p63 underlies Rapp-Hodgkin ectodermal dysplasia. J Dent Res 82:433-7 (Pubitemid 41766007)
    • (2003) Journal of Dental Research , vol.82 , Issue.6 , pp. 433-437
    • Kantoputra, P.N.1    Hamada, T.2    Kumchai, T.3    McGrath, J.A.4
  • 51
    • 24344447780 scopus 로고    scopus 로고
    • P63 deficiency activates a program of cellular senescence and leads to accelerated aging
    • DOI 10.1101/gad.342305
    • Keyes WM, Wu Y, Vogel H et al. (2005) p63 deficiency activates a program of cellular senescence and leads to accelerated aging. Genes Dev 19:1986-99 (Pubitemid 41247957)
    • (2005) Genes and Development , vol.19 , Issue.17 , pp. 1986-1999
    • Keyes, W.M.1    Wu, Y.2    Vogel, H.3    Guo, X.4    Lowe, S.W.5    Mills, A.A.6
  • 53
    • 18644374446 scopus 로고    scopus 로고
    • Mutations in IRF6 cause Van der Woude and popliteal pterygium syndromes
    • Kondo S, Schutte BC, Richardson RJ et al. (2002) Mutations in IRF6 cause Van der Woude and popliteal pterygium syndromes. Nat Genet 32:285-9
    • (2002) Nat Genet , vol.32 , pp. 285-289
    • Kondo, S.1    Schutte, B.C.2    Richardson, R.J.3
  • 55
    • 33847054771 scopus 로고    scopus 로고
    • Conflicting roles for p63 in skin development and carcinogenesis
    • Koster MI, Dai D, Roop DR (2007b) Conflicting roles for p63 in skin development and carcinogenesis. Cell Cycle 6:269-73
    • (2007) Cell Cycle , vol.6 , pp. 269-273
    • Koster, M.I.1    Dai, D.2    Roop, D.R.3
  • 56
    • 0942301281 scopus 로고    scopus 로고
    • P63 is the molecular switch for initiation of an epithelial stratification program
    • DOI 10.1101/gad.1165104
    • Koster MI, Kim S, Mills AA et al. (2004) p63 is the molecular switch for initiation of an epithelial stratification program. Genes Dev 18:126-31 (Pubitemid 38141780)
    • (2004) Genes and Development , vol.18 , Issue.2 , pp. 126-131
    • Koster, M.I.1    Kim, S.2    Mills, A.A.3    DeMayo, F.J.4    Roop, D.R.5
  • 57
    • 33646245191 scopus 로고    scopus 로고
    • Reactivation of developmentally expressed p63 isoforms predisposes to tumor development and progression
    • Koster MI, Lu SL, White LD et al. (2006) Reactivation of developmentally expressed p63 isoforms predisposes to tumor development and progression. Cancer Res 66:3981-6
    • (2006) Cancer Res , vol.66 , pp. 3981-3986
    • Koster, M.I.1    Lu, S.L.2    White, L.D.3
  • 58
    • 69249091010 scopus 로고    scopus 로고
    • DeltaNp63 knockdown mice: A mouse model for AEC syndrome
    • Koster MI, Marinari B, Payne AS et al. (2009) DeltaNp63 knockdown mice: A mouse model for AEC syndrome. Am J Med Genet A 149A:1942-7
    • (2009) Am J Med Genet A , vol.149 A , pp. 1942-1947
    • Koster, M.I.1    Marinari, B.2    Payne, A.S.3
  • 59
    • 77957371805 scopus 로고    scopus 로고
    • Genome-wide profiling of p63 DNA-binding sites identifies an element that regulates gene expression during limb development in the 7q21 SHFM1 locus
    • Kouwenhoven EN, Van Heeringen SJ, Tena JJ et al. (2010) Genome-wide profiling of p63 DNA-binding sites identifies an element that regulates gene expression during limb development in the 7q21 SHFM1 locus. PLoS Genet 6:e1001065
    • (2010) PLoS Genet , vol.6
    • Kouwenhoven, E.N.1    Van Heeringen, S.J.2    Tena, J.J.3
  • 61
    • 23144455530 scopus 로고    scopus 로고
    • Differential expression of p63 isoforms in female reproductive organs
    • DOI 10.1016/j.mod.2005.04.008, PII S0925477305000614
    • Kurita T, Cunha GR, Robboy SJ et al. (2005) Differential expression of p63 isoforms in female reproductive organs. Mech Dev 122:1043-55 (Pubitemid 41080028)
    • (2005) Mechanisms of Development , vol.122 , Issue.9 , pp. 1043-1055
    • Kurita, T.1    Cunha, G.R.2    Robboy, S.J.3    Mills, A.A.4    Medina, R.T.5
  • 64
    • 33745509671 scopus 로고    scopus 로고
    • A mutation of the p63 gene in non-syndromic cleft lip
    • Leoyklang P, Siriwan P, Shotelersuk V (2006) A mutation of the p63 gene in non-syndromic cleft lip. J Med Genet 43:e28
    • (2006) J Med Genet , vol.43
    • Leoyklang, P.1    Siriwan, P.2    Shotelersuk, V.3
  • 65
    • 73449139088 scopus 로고    scopus 로고
    • P63 and p73 transcriptionally regulate genes involved in DNA repair
    • Lin YL, Sengupta S, Gurdziel K et al. (2009) p63 and p73 transcriptionally regulate genes involved in DNA repair. PLoS Genet 5:e1000680
    • (2009) PLoS Genet , vol.5
    • Lin, Y.L.1    Sengupta, S.2    Gurdziel, K.3
  • 66
    • 0037385427 scopus 로고    scopus 로고
    • A role for the mesenchymal T-box gene Brachyury in AER formation during limb development
    • DOI 10.1242/dev.00354
    • Liu C, Nakamura E, Knezevic V et al. (2003) A role for the mesenchymal T-box gene Bra-chyury in AER formation during limb development. Development 130:1327-37 (Pubitemid 36410781)
    • (2003) Development , vol.130 , Issue.7 , pp. 1327-1337
    • Liu, C.1    Nakamura, E.2    Knezevic, V.3    Hunter, S.4    Thompson, K.5    Mackem, S.6
  • 67
    • 38349131679 scopus 로고    scopus 로고
    • P63 null mutation protects mouse oocytes from radio-induced apoptosis
    • Livera G, Petre-Lazar B, Guerquin MJ et al. (2008) p63 null mutation protects mouse oocytes from radio-induced apoptosis. Reproduction 135:3-12
    • (2008) Reproduction , vol.135 , pp. 3-12
    • Livera, G.1    Petre-Lazar, B.2    Guerquin, M.J.3
  • 69
    • 70350674206 scopus 로고    scopus 로고
    • Identification and functional characterization of two new transcriptional variants of the human p63 gene
    • Mangiulli M, Valletti A, Caratozzolo MF et al. (2009) Identification and functional characterization of two new transcriptional variants of the human p63 gene. Nucleic Acids Res 37:6092-104
    • (2009) Nucleic Acids Res , vol.37 , pp. 6092-6104
    • Mangiulli, M.1    Valletti, A.2    Caratozzolo, M.F.3
  • 70
    • 58149360788 scopus 로고    scopus 로고
    • IKKalpha is a p63 transcriptional target involved in the pathogenesis of ectodermal dysplasias
    • Marinari B, Ballaro C, Koster MI et al. (2009) IKKalpha is a p63 transcriptional target involved in the pathogenesis of ectodermal dysplasias. J Invest Dermatol 129:60-9
    • (2009) J Invest Dermatol , vol.129 , pp. 60-69
    • Marinari, B.1    Ballaro, C.2    Koster, M.I.3
  • 72
    • 55349124977 scopus 로고    scopus 로고
    • DeltaNp63 is essential for epidermal commitment of embryonic stem cells
    • Medawar A, Virolle T, Rostagno P et al. (2008) DeltaNp63 is essential for epidermal commitment of embryonic stem cells. PLoS ONE 3:e3441
    • (2008) PLoS ONE , vol.3
    • Medawar, A.1    Virolle, T.2    Rostagno, P.3
  • 73
    • 33847055513 scopus 로고    scopus 로고
    • P63 in skin appendage development
    • Mikkola ML (2007) p63 in skin appendage development. Cell Cycle 6:285-90
    • (2007) Cell Cycle , vol.6 , pp. 285-290
    • Mikkola, M.L.1
  • 74
    • 77449151036 scopus 로고    scopus 로고
    • Treasure or artifact: A decade of p63 research speaks for itself
    • author reply 4-6
    • Mikkola ML, Costanzo A, Thesleff I et al. (2010) Treasure or artifact: a decade of p63 research speaks for itself. Cell Death Differ 17:180-3; author reply 4-6
    • (2010) Cell Death Differ , vol.17 , pp. 180-183
    • Mikkola, M.L.1    Costanzo, A.2    Thesleff, I.3
  • 75
    • 0036193580 scopus 로고    scopus 로고
    • Conditional inactivation of p63 by Cre-mediated excision
    • DOI 10.1002/gene.10067
    • Mills AA, Qi Y, Bradley A (2002) Conditional inactivation of p63 by Cre-mediated excision. Genesis 32:138-41 (Pubitemid 34211720)
    • (2002) Genesis , vol.32 , Issue.2 , pp. 138-141
    • Mills, A.A.1    Qi, Y.2    Bradley, A.3
  • 76
    • 0033594491 scopus 로고    scopus 로고
    • P63 is a p53 homologue required for limb and epidermal morphogenesis
    • DOI 10.1038/19531
    • Mills AA, Zheng B, Wang XJ et al. (1999) p63 is a p53 homologue required for limb and epidermal morphogenesis. Nature 398:708-13 (Pubitemid 29197649)
    • (1999) Nature , vol.398 , Issue.6729 , pp. 708-713
    • Mills, A.A.1    Zheng, B.2    Wang, X.-J.3    Vogel, H.4    Roop, D.R.5    Bradley, A.6
  • 77
    • 77951865156 scopus 로고    scopus 로고
    • A regulatory feedback loop involving p63 and IRF6 links the pathogenesis of 2 genetically different human ectodermal dysplasias
    • Moretti F, Marinari B, Lo Iacono N et al. (2010) A regulatory feedback loop involving p63 and IRF6 links the pathogenesis of 2 genetically different human ectodermal dysplasias. J Clin Invest 120:1570-7
    • (2010) J Clin Invest , vol.120 , pp. 1570-1577
    • Moretti, F.1    Marinari, B.2    Lo Iacono, N.3
  • 78
    • 72249100428 scopus 로고    scopus 로고
    • Mutant p53 drives invasion by promoting integrin recycling
    • Muller PA, Caswell PT, Doyle B et al. (2009) Mutant p53 drives invasion by promoting integrin recycling. Cell 139:1327-41
    • (2009) Cell , vol.139 , pp. 1327-1341
    • Muller, P.A.1    Caswell, P.T.2    Doyle, B.3
  • 79
    • 33746353085 scopus 로고    scopus 로고
    • Derivation of the consensus DNA-binding sequence for p63 reveals unique requirements that are distinct from p53
    • DOI 10.1016/j.febslet.2006.07.004, PII S0014579306008374
    • Ortt K, Sinha S (2006) Derivation of the consensus DNA-binding sequence for p63 reveals unique requirements that are distinct from p53. FEBS Lett 580:4544-50 (Pubitemid 44118257)
    • (2006) FEBS Letters , vol.580 , Issue.18 , pp. 4544-4550
    • Ortt, K.1    Sinha, S.2
  • 81
    • 33847073407 scopus 로고    scopus 로고
    • Transcriptional programs regulated by p63 in normal epithelium and tumors
    • Perez CA, Pietenpol JA (2007) Transcriptional programs regulated by p63 in normal epithelium and tumors. Cell Cycle 6:246-54
    • (2007) Cell Cycle , vol.6 , pp. 246-254
    • Perez, C.A.1    Pietenpol, J.A.2
  • 82
    • 67349253075 scopus 로고    scopus 로고
    • A 9.3Mb microdeletion of 3q27.3q29 associated with psychomotor and growth delay, tricuspid valve dysplasia and bifid thumb
    • Pollazzon M, Grosso S, Papa FT et al. (2009) A 9.3Mb microdeletion of 3q27.3q29 associated with psychomotor and growth delay, tricuspid valve dysplasia and bifid thumb. Eur J Med Genet 52:131-3
    • (2009) Eur J Med Genet , vol.52 , pp. 131-133
    • Pollazzon, M.1    Grosso, S.2    Papa, F.T.3
  • 83
    • 63449086401 scopus 로고    scopus 로고
    • Transcriptional network of p63 in human keratinocytes
    • Pozzi S, Zambelli F, Merico D et al. (2009) Transcriptional network of p63 in human keratinocytes. PLoS ONE 4:e5008
    • (2009) PLoS ONE , vol.4
    • Pozzi, S.1    Zambelli, F.2    Merico, D.3
  • 85
    • 55049105999 scopus 로고    scopus 로고
    • Disruption of an AP-2alpha binding site in an IRF6 enhancer is associated with cleft lip
    • Rahimov F, Marazita ML, Visel A et al. (2008) Disruption of an AP-2alpha binding site in an IRF6 enhancer is associated with cleft lip. Nat Genet 40:1341-7
    • (2008) Nat Genet , vol.40 , pp. 1341-1347
    • Rahimov, F.1    Marazita, M.L.2    Visel, A.3
  • 86
    • 69249135920 scopus 로고    scopus 로고
    • Spectrum of p63 mutations in a selected patient cohort affected with ankyloblepharon-ectodermal defects-cleft lip/palate syndrome (AEC)
    • Rinne T, Bolat E, Meijer R et al. (2009) Spectrum of p63 mutations in a selected patient cohort affected with ankyloblepharon-ectodermal defects-cleft lip/palate syndrome (AEC). Am J Med Genet A 149A:1948-51
    • (2009) Am J Med Genet A , vol.149 A , pp. 1948-1951
    • Rinne, T.1    Bolat, E.2    Meijer, R.3
  • 89
    • 0036558218 scopus 로고    scopus 로고
    • The D1x5 and D1x6 homeobox genes are essential for craniofacial, axial, and appendicular skeletal development
    • DOI 10.1101/gad.988402
    • Robledo RF, Rajan L, Li X et al. (2002) The Dlx5 and Dlx6 homeobox genes are essential for craniofacial, axial, and appendicular skeletal development. Genes Dev 16:1089-101 (Pubitemid 34507198)
    • (2002) Genes and Development , vol.16 , Issue.9 , pp. 1089-1101
    • Robledo, R.F.1    Rajan, L.2    Li, X.3    Lufkin, T.4
  • 90
    • 34247252481 scopus 로고    scopus 로고
    • A functional enhancer of keratin14 is a direct transcriptional target of ΔNp63
    • DOI 10.1038/sj.jid.5700652, PII 5700652
    • Romano RA, Birkaya B, Sinha S (2007) A functional enhancer of keratin14 is a direct transcriptional target of deltaNp63. J Invest Dermatol 127:1175-86 (Pubitemid 46625134)
    • (2007) Journal of Investigative Dermatology , vol.127 , Issue.5 , pp. 1175-1186
    • Romano, R.-A.1    Birkaya, B.2    Sinha, S.3
  • 91
    • 66049096917 scopus 로고    scopus 로고
    • An active role of the DeltaN isoform of p63 in regulating basal keratin genes K5 and K14 and directing epidermal cell fate
    • Romano RA, Ortt K, Birkaya B et al. (2009) An active role of the DeltaN isoform of p63 in regulating basal keratin genes K5 and K14 and directing epidermal cell fate. PLoS ONE 4:e5623
    • (2009) PLoS ONE , vol.4
    • Romano, R.A.1    Ortt, K.2    Birkaya, B.3
  • 92
    • 77951244112 scopus 로고    scopus 로고
    • Abnormal hair follicle development and altered cell fate of follicular keratinocytes in transgenic mice expressing DeltaNp63al-pha
    • Romano RA, Smalley K, Liu S et al. (2010) Abnormal hair follicle development and altered cell fate of follicular keratinocytes in transgenic mice expressing DeltaNp63al-pha. Development 137:1431-9
    • (2010) Development , vol.137 , pp. 1431-1439
    • Romano, R.A.1    Smalley, K.2    Liu, S.3
  • 93
    • 11144322225 scopus 로고    scopus 로고
    • Strong evidence of linkage disequilibrium between polymorphisms at the IRF6 locus and nonsyndromic cleft lip with or without cleft palate, in an Italian population
    • DOI 10.1086/427344
    • Scapoli L, Palmieri A, Martinelli M et al. (2005) Strong evidence of linkage disequilibrium between polymorphisms at the IRF6 locus and nonsyndromic cleft lip with or without cleft palate, in an Italian population. Am J Hum Genet 76:180-3 (Pubitemid 40023778)
    • (2005) American Journal of Human Genetics , vol.76 , Issue.1 , pp. 180-183
    • Scapoli, L.1    Palmieri, A.2    Martinelli, M.3    Pezzetti, F.4    Carinci, P.5    Tognon, M.6    Carinci, F.7
  • 95
    • 77950521140 scopus 로고    scopus 로고
    • Interference with the p53 family network contributes to the gain of oncogenic function of mutant p53 in hepatocellular carcinoma
    • Schilling T, Kairat A, Melino G et al. (2010) Interference with the p53 family network contributes to the gain of oncogenic function of mutant p53 in hepatocellular carcinoma. Biochem Biophys Res Commun 394:817-23
    • (2010) Biochem Biophys Res Commun , vol.394 , pp. 817-823
    • Schilling, T.1    Kairat, A.2    Melino, G.3
  • 96
    • 34247511981 scopus 로고    scopus 로고
    • P63 Is Essential for the Proliferative Potential of Stem Cells in Stratified Epithelia
    • DOI 10.1016/j.cell.2007.02.045, PII S0092867407003844
    • Senoo M, Pinto F, Crum CP et al. (2007) p63 Is essential for the proliferative potential of stem cells in stratified epithelia. Cell 129:523-36 (Pubitemid 46660965)
    • (2007) Cell , vol.129 , Issue.3 , pp. 523-536
    • Senoo, M.1    Pinto, F.2    Crum, C.P.3    McKeon, F.4
  • 97
    • 40949141331 scopus 로고    scopus 로고
    • P-cadherin is a p63 target gene with a crucial role in the developing human limb bud and hair follicle
    • DOI 10.1242/dev.006718
    • Shimomura Y, Wajid M, Shapiro L et al. (2008) P-cadherin is a p63 target gene with a crucial role in the developing human limb bud and hair follicle. Development 135:743-53 (Pubitemid 351405027)
    • (2008) Development , vol.135 , Issue.4 , pp. 743-753
    • Shimomura, Y.1    Wajid, M.2    Shapiro, L.3    Christiano, A.M.4
  • 99
    • 63049131295 scopus 로고    scopus 로고
    • Regulation of p53 family members by the ubiquitin-like SUMO system
    • Stehmeier P, Muller S (2009) Regulation of p53 family members by the ubiquitin-like SUMO system. DNA Repair (Amst) 8:491-8
    • (2009) DNA Repair (Amst , vol.8 , pp. 491-498
    • Stehmeier, P.1    Muller, S.2
  • 100
    • 77958558613 scopus 로고    scopus 로고
    • TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs
    • Su X, Chakravarti D, Cho MS et al. (2010) TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs. Nature 467:986-90
    • (2010) Nature , vol.467 , pp. 986-990
    • Su, X.1    Chakravarti, D.2    Cho, M.S.3
  • 101
    • 67650461955 scopus 로고    scopus 로고
    • Rescue of key features of the p63-null epithelial phenotype by inactivation of Ink4a and Arf
    • Su X, Cho MS, Gi YJ et al. (2009a) Rescue of key features of the p63-null epithelial phenotype by inactivation of Ink4a and Arf. EMBO J 28:1904-15
    • (2009) EMBO J , vol.28 , pp. 1904-1915
    • Su, X.1    Cho, M.S.2    Gi, Y.J.3
  • 102
    • 67649159970 scopus 로고    scopus 로고
    • TAp63 prevents premature aging by promoting adult stem cell maintenance
    • Su X, Paris M, Gi YJ et al. (2009b) TAp63 prevents premature aging by promoting adult stem cell maintenance. Cell Stem Cell 5:64-75
    • (2009) Cell Stem Cell , vol.5 , pp. 64-75
    • Su, X.1    Paris, M.2    Gi, Y.J.3
  • 105
    • 77951849894 scopus 로고    scopus 로고
    • Cooperation between the transcription factors p63 and IRF6 is essential to prevent cleft palate in mice
    • Thomason HA, Zhou H, Kouwenhoven EN et al. (2010) Cooperation between the transcription factors p63 and IRF6 is essential to prevent cleft palate in mice. J Clin Invest 120:1561-9
    • (2010) J Clin Invest , vol.120 , pp. 1561-1569
    • Thomason, H.A.1    Zhou, H.2    Kouwenhoven, E.N.3
  • 106
    • 33751230475 scopus 로고    scopus 로고
    • P63 regulates proliferation and differentiation of developmentally mature keratinocytes
    • DOI 10.1101/gad.1463206
    • Truong AB, Kretz M, Ridky TW et al. (2006) p63 regulates proliferation and differentiation of developmentally mature keratinocytes. Genes Dev 20:3185-97 (Pubitemid 44790632)
    • (2006) Genes and Development , vol.20 , Issue.22 , pp. 3185-3197
    • Truong, A.B.1    Kretz, M.2    Ridky, T.W.3    Kimmel, R.4    Khavari, P.A.5
  • 107
    • 49649122346 scopus 로고    scopus 로고
    • Homozygous WNT10b mutation and complex inheritance in split-hand/foot malformation
    • Ugur SA, Tolun A (2008) Homozygous WNT10b mutation and complex inheritance in split-hand/foot malformation. Hum Mol Genet 17:2644-53
    • (2008) Hum Mol Genet , vol.17 , pp. 2644-2653
    • Ugur, S.A.1    Tolun, A.2
  • 110
    • 67650727439 scopus 로고    scopus 로고
    • The alpha/beta carboxy-terminal domains of p63 are required for skin and limb development New insights from the Brdm2 mouse which is not a complete p63 knockout but expresses p63 gamma-like proteins
    • Wolff S, Talos F, Palacios G et al. (2009) The alpha/beta carboxy-terminal domains of p63 are required for skin and limb development. New insights from the Brdm2 mouse which is not a complete p63 knockout but expresses p63 gamma-like proteins. Cell Death Differ 16:1108-17
    • (2009) Cell Death Differ , vol.16 , pp. 1108-1117
    • Wolff, S.1    Talos, F.2    Palacios, G.3
  • 112
    • 33847057887 scopus 로고    scopus 로고
    • Relationships between p63 binding, DNA sequence, transcription activity, and biological function in human cells
    • DOI 10.1016/j.molcel.2006.10.018
    • Yang A, Zhu Z, Kapranov P et al. (2006) Relationships between p63 binding, DNA sequence, transcription activity, and biological function in human cells. Mol Cell 24:593-602 (Pubitemid 350284225)
    • (2006) Molecular Cell , vol.24 , Issue.4 , pp. 593-602
    • Yang, A.1    Zhu, Z.2    Kapranov, P.3    McKeon, F.4    Church, G.M.5    Gingeras, T.R.6    Struhl, K.7
  • 113
    • 40749111551 scopus 로고    scopus 로고
    • A skin microRNA promotes differentiation by repressing 'stemness'
    • DOI 10.1038/nature06642, PII NATURE06642
    • Yi R, Poy MN, Stoffel M et al. (2008) A skin microRNA promotes differentiation by repressing "stemness". Nature 452:225-9 (Pubitemid 351380241)
    • (2008) Nature , vol.452 , Issue.7184 , pp. 225-229
    • Yi, R.1    Poy, M.N.2    Stoffel, M.3    Fuchs, E.4


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